Online Trial Tracker - Larvol Sigma

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

Comtan (entacapone) / Novartis, Orion Corp

2008-003581-26: Pharmacokinetics of levodopa using duodenal levodopa/carbidopa infusion with and without oral COMT inhibitors

Ongoing

Europe

Duodopa, Comtess, Tasmar, Duodopa, Comtess, Tasmar

Dept of Neuroscience, Uppsala University

Parkinson\'s disease (G20.9), advanced, patients presently on Duodopa treatment.

NCT00262470: Treatment of Orthostatic Intolerance

Active, not recruiting

1/2

150

Acetazolamide, Diamox, Atomoxetine, Strattera, NO Drug, Clonidine, Catapres, Entacapone, Comtan, Entacapone & Propranolol, Inderal, Atomoxetine & Propranolol, Indomethacin, Indocin, Mecamylamine, inversine, Isosorbide Dinitrate, Isordil, Melatonin, Midodrine, pro-amatine, Modafinil, provigil, Octreotide, sandostatin, Placebo, Propranolol, Modafinil & Propranolol, Provigil, Sertraline, Zoloft, IV Saline, NaCl solution (0.9%), Drinking Water, Breathing Device, memantine, Namenda, Abdominal binder

Satish R. Raj, National Center for Advancing Translational Sciences (NCATS)

Tachycardia, Chronic Orthostatic Intolerance

12/25

NCT04006769: Entacapone Combination With Imatinib for Treatment of GIST

Completed

RoW

Entacapone, Comtan, Comtess, Imatinib Mesylate, Gleevec

Xiangya Hospital of Central South University

Gastrointestinal Stromal Tumor, Malignant

08/22

NCT05976737: Bioequivalence Study of Entacapone,Levodopa and Carbidopa Tablets in Healthy Chinese Subjects

Not yet recruiting

Test (T) Entacapone,Levodopa and Carbidopa Tablets (II), Reference (R) Entacapone,Levodopa and Carbidopa Tablets (II)

The Affiliated Hospital of Qingdao University

Healthy

09/23

07/24

NCT06180720: Bioequivalence Study of Entacapone,Levodopa and Carbidopa Tablets in the Postprandial State in Healthy Chinese Subjects

Not yet recruiting

Test (T) Entacapone,Levodopa and Carbidopa Tablets (II), Reference (R) Entacapone,Levodopa and Carbidopa Tablets (II)

The Affiliated Hospital of Qingdao University

Healthy

01/24

11/24

NCT04246437: [18F]F-DOPA Imaging in Patients With Autonomic Failure

Recruiting

[18F]FDOPA, Carbidopa 200mg oral dose, Lodosyn, Entacapone 400mg oral dose, Comtan

Daniel Claassen

Autonomic Failure, Pure Autonomic Failure, Parkinson Disease, Multiple System Atrophy, Dementia With Lewy Bodies

02/25

ChiCTR1900022534: Efficacy of entacapone and pramipexole for non-motor symptoms of Parkinson’s disease: a prospective randomized controlled trial

Not yet recruiting

N/A

388

Patients in the entacapone group will be administered entacapone (Novartis; import drug registration certificate number: H20160680), 10 times per day, 200 mg each time, for 3 weeks. ;Patients in the pramipexole group will be administered pramipexole (Boehringer-Ingelheim; import drug registration certificate number: 20140918) , 3 times per day, 1 mg each time, for 3 weeks.

Geriatric Hospital of Hainan; Geriatric Hospital of Hainan, Self-funded

non-motor symptoms of Parkinson’s disease



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