| risperidone / Generic mfg. |
NCT00253110: A Comparison of Risperidone With Haloperidol in Patients With Schizophrenia and Schizoaffective Disorder |
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| Completed | 4 | 396 | US | risperidone, haloperidol | Janssen, LP | Schizophrenia, Schizoaffective Disorder | | 09/98 | | |
NCT00378183: A Study Comparing Three Strategies to Switch Patients With Schizophrenia or Schizoaffective Disorder to Risperidone After Unsuccessful Treatment With Olanzapine. |
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| Completed | 4 | 120 | US | risperidone | Janssen, LP | Schizoaffective Disorder, Schizophrenia | | 05/02 | | |
NCT00034905: A Comparison of Seroquel vs. Risperidone in Schizophrenia |
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| Completed | 4 | | US | quetiapine fumarate vs risperidone | AstraZeneca | Schizophrenia | 09/02 | 09/02 | | |
NCT00237861: Effectiveness of Atypical Versus Conventional Antipsychotics in Treating Schizophrenia |
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| Completed | 4 | | US | risperidone, olanzapine, quetiapine | Yale University, National Institute of Mental Health (NIMH) | Schizophrenia | 12/02 | | | |
NCT00249171: A Study of Risperidone in Combination With Lorazepam Compared With Standard Therapy for Emergency Treatment of Schizophrenic Patients |
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| Completed | 4 | 226 | Europe | risperidone | Janssen Pharmaceutica N.V., Belgium | Schizophrenia, Psychotic Disorders, Emergency Treatment | | 02/03 | | |
NCT00236379: A Study of the Effects of Risperidone and Olanzapine on Blood Glucose (Sugar) in Patients With Schizophrenia or Schizoaffective Disorder |
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| Completed | 4 | 59 | US | Olanzapine, Risperidone | Janssen, LP | Schizophrenia, Diabetes Mellitus | | 08/03 | | |
NCT00485498: Managing Acute Schizophrenia, a Comparison Between Two Atypical Antipsychotics |
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| Completed | 4 | 122 | RoW | Olanzapine Hydrochloride, Risperidone | Eli Lilly and Company | Schizophrenia | | 12/03 | | |
NCT00061802: Efficacy and Safety of Two Atypical Antipsychotics vs. Placebo in Patients With an Acute Exacerbation of Either Schizophrenia or Schizoaffective Disorder |
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| Completed | 4 | 225 | US, Europe, RoW | risperidone, quetiapine | Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Janssen, LP | Schizophrenia, Schizoaffective Disorder | | 02/04 | | |
| Completed | 4 | | US | Risperidone, Olanzapine, Quetiapine | US Department of Veterans Affairs | Schizophrenia | | 09/04 | | |
NCT00261430: A 2-year Study of Patients With Schizophrenia Who Are Treated With Long-acting Injectable Risperidone. |
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| Completed | 4 | 650 | US | GAIN Acceptance Approach | Janssen, LP | Schizophrenia | | 10/04 | | |
| Completed | 4 | 1600 | US | perphenazine, olanzapine, quetiapine, risperidone, ziprasidone, clozapine, fluphenazine decanoate | National Institute of Mental Health (NIMH) | Schizophrenia | | 12/04 | | |
NCT00848432: Risperidone Maintenance Treatment in Schizophrenia |
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| Completed | 4 | 404 | RoW | risperidone, Risperdal | Capital Medical University | Schizophrenia | 12/04 | 12/04 | | |
NCT00159081: One Year Drug Treatment in First-Episode Schizophrenia |
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| Completed | 4 | 159 | Europe | Haloperidol, Risperidone (drug) | Heinrich-Heine University, Duesseldorf, German Federal Ministry of Education and Research, German Research Network On Schizophrenia, Janssen-Cilag Ltd., University of Bonn, Humboldt-Universität zu Berlin, University of München, University of Göttingen, University of Cologne, Mainz University, University Hospital Tuebingen, Universität Duisburg-Essen, University of Mannheim, University of Jena, Martin-Luther-Universität Halle-Wittenberg, RWTH Aachen University, University of Wuerzburg | Schizophrenia | 06/05 | 06/05 | | |
NCT00208143: Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia |
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| Completed | 4 | 20 | US | Quetiapine, Risperidone | Creighton University, AstraZeneca | Schizophrenia, Schizoaffective Disorder, Substance Abuse, Substance Dependence | | 12/05 | | |
NCT00108368: The Effects of Risperidone and Olanzapine on Thinking |
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| Completed | 4 | | US | Risperidone, Olanzapine | US Department of Veterans Affairs, Janssen, LP | Schizophrenia, Psychotic Disorders | | 03/06 | | |
NCT00254241: Safety and Efficacy of Seroquel in First Episode Schizophrenia |
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| Completed | 4 | 80 | Europe | Seroquel and Risperidone | AstraZeneca | Schizophrenia | | 06/06 | | |
| Completed | 4 | 500 | RoW | Aripiprazole, Solian, Olanzapine, Seroquel, Risperidone | Korea Otsuka Pharmaceutical Co., Ltd. | Schizophrenia | 06/06 | 10/07 | | |
NCT00224315: Clozapine-Augmentation With Ziprasidone or Risperidone, a Randomized, Prospective Trial |
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| Completed | 4 | 24 | Europe | ziprasidone, risperidone | Central Institute of Mental Health, Mannheim | Schizophrenia, Schizoaffective Disorder | | 09/06 | | |
NCT00203788: Improving Work Outcome in People With Recent-onset Schizophrenia |
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| Completed | 4 | 87 | US | Individual Placement and Support, Workplace Fundamentals Module, Brokered Vocational Rehabilitation, Oral risperidone, Risperdal, Skills training group | University of California, Los Angeles, National Institute of Mental Health (NIMH) | Schizophrenia | 12/06 | 12/06 | | |
NCT00314613: Functional Brain Imaging and Employment in First-Episode Psychotic Patients Treated With Risperdal |
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| Terminated | 4 | 30 | US | Antipsychotic/Risperidone Consta | Duke University, Janssen, LP | Schizophrenia | 12/06 | | | |
NCT00289861: Risperidone Augmentation in Patients With Schizophrenia |
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| Completed | 4 | 24 | US | Risperidone, placebo | Massachusetts General Hospital, Stanley Medical Research Institute | Schizophrenia | 03/07 | 03/07 | | |
NCT00232687: A Switch Study of BMS-337039 in Schizophrenic Out-patients |
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| Completed | 4 | 450 | Europe | Aripiprazole, Abilify | Otsuka Pharmaceutical Development & Commercialization, Inc., Otsuka America Pharmaceutical | Schizophrenia | 04/07 | 04/07 | | |
| Completed | 4 | 125 | US | Olanzapine, Risperidone | Northwell Health, National Institute of Mental Health (NIMH), The Zucker Hillside Hospital | Schizophrenia | 05/07 | 05/07 | | |
| Completed | 4 | 116 | US | Risperidone, Risperdal, Olanzapine (enrollment closed in this treatment), Zyprexa, Molindone, Moban | University of North Carolina, Chapel Hill, National Institute of Mental Health (NIMH) | Schizophrenia | 05/07 | 05/07 | | |
NCT00216632: A Study of Treatment Success in Changing From Olanzapine to Long-acting Injectable Risperidone (RISPERDAL® CONSTA™) |
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| Completed | 4 | 99 | Europe | risperidone | Janssen Pharmaceutica N.V., Belgium | Schizophrenia, Psychotic Disorders | 07/07 | 07/07 | | |
NCT00231335: Efficacy and Safety Study of Escitalopram Augmentation in Treatment Resistant Schizophrenia |
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| Completed | 4 | 30 | US | escitalopram | Emory University, Forest Laboratories | Schizophrenia, Schizoaffective Disorder | | 07/07 | | |
NCT00287820: Comparative Effects of Chronic Treatment With Olanzapine and Risperidone on Glucose and Lipid Metabolism |
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| Completed | 4 | 46 | US | Olanzapine, ayprexa, olanzapine, zyprexa, risperidone, riperidal | Nathan Kline Institute for Psychiatric Research, Eli Lilly and Company | Schizophrenia, Diabetes, Metabolic Syndrome, Hyperglycemia | | 09/07 | | |
| Completed | 4 | 48 | RoW | Risperidone, Respidon, risperidone, Citalopram, Citopam, Placebo | National Institute of Mental Health and Neuro Sciences, India | Schizophrenia, Negative Symptoms | 09/07 | 09/07 | | |
NCT00325689: Aripiprazole Used as Dual Therapy in the Treatement of Patients With Chronic Stable Schizophrenia or Schizoaffective Disorder. |
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| Completed | 4 | 323 | US | Quetiapine or Risperidone + Aripiprazole, Abilify, Quetiapine or Risperidone + placebo | Otsuka Pharmaceutical Development & Commercialization, Inc., Otsuka America Pharmaceutical | Schizophrenia, Schizoaffective Disorder | 10/07 | 10/07 | | |
ACPIOS, NCT00654576: Effectiveness of Antipsychotic Combination With Psychosocial Intervention on Outcome of Patients With Schizophrenia |
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| Completed | 4 | 1400 | RoW | Chlorpromazine, Sulpiride, Clozapine, Olanzapine, Risperidone, Quetiapine, Aripitrazole, psychosocial intervention | Central South University, Shanghai Mental Health Center, Sichuan University, Capital Medical University, Nanjing Medical University, Jiangxi Mental Hospital, Hunan Mental Hospital, Guangzhou Mental Hospital, Chongqing Metal Institute, Henan Mental Hospital | Schizophrenia | 12/07 | 12/07 | | |
NCT00337662: Efficacy Study of Early Onset of Antipsychotic Drug Action in Schizophrenia |
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| Completed | 4 | 628 | US, RoW | olanzapine, LY170053, Zyprexa, risperidone | Eli Lilly and Company | Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder | 12/07 | 12/07 | | |
NCT00140166: Treatment of Acute Schizophrenia With Vitamin Therapy |
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| Completed | 4 | 55 | RoW | niacinamide, pyridoxine, ascorbate | Beersheva Mental Health Center, Supported by a Hilton Family Foundation grant to, International Schizophrenia Foundation | Acute Schizophrenia | | 05/08 | | |
NCT00190749: Safety Study of Olanzapine and a Comparator in Patients With Schizophrenia and Schizoaffective Disorder |
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| Completed | 4 | 130 | US | olanzapine, LY170053, Zyprexa, risperidone | Eli Lilly and Company | Schizophrenia, Schizoaffective Disorder | 06/08 | 06/08 | | |
NCT00535132: Study to Measure Drug Satisfaction of Patients With Schizophrenia After Switching From Risperidone to Paliperidone |
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| Completed | 4 | 201 | US, Europe, RoW | Oral Risperidone, Paliperidone ER | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Schizophrenia | 07/08 | 07/08 | | |
NCT00498004: Quality of Life (QOL) in Female Patient With Schizophrenia |
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| Terminated | 4 | 100 | RoW | Quetiapine, Risperidone | Inje University | Schizophrenia | 09/08 | 09/08 | | |
NCT00206102: A Study of the Cataractogenic Potential of Seroquel and Risperdal in the Treatment of Participants With Schizophrenia or Schizoaffective Disorder |
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| Completed | 4 | 1098 | US | quetiapine fumarate, Seroquel, ICI 204,636, risperidone | AstraZeneca | Schizophrenia, Schizoaffective Disorder | 10/08 | 10/08 | | |
NCT00299702: Evaluation of Effectiveness of Risperdal® Consta® Compared to Abilify® Over a Two-year Period in Patients With Schizophrenia |
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| Completed | 4 | 355 | US | Abilify, Risperidal Consta | Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Janssen, LP | Schizophrenia, Psychotic Disorders | 01/09 | 01/09 | | |
NCT00508157 / 2007-001217-42: A Phase 4 Study to Assess the Effects of Aripiprazole Versus Other Atypical Antipsychotics in the Treatment of Schizophrenic Patients With Metabolic Syndrome |
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| Terminated | 4 | 125 | Europe, RoW | Aripiprazole, Abilify, BMS-337039, Continued Antipsychotic (Risperidone or Quetiapine or Olanzapine) | Bristol-Myers Squibb, Otsuka America Pharmaceutical | Metabolic Syndrome, Schizophrenia | 03/09 | 03/09 | | |
NCT00859872: Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol Intramuscular (IM) Injection for Treatment of Acute Psychotic Agitation in Schizophrenia |
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| Completed | 4 | 198 | RoW | risperidone oral solution, haloperidol | Central South University, Wuhan Mental Health Institute, Capital Medical University, Shanghai Mental Health Center, Guangzhou Mental Hospital, Chongqing Mental Hospital | Schizophrenia | 03/09 | 03/09 | | |
NCT00998608: Comparison of the Efficacy and Safety of Risperidone Versus Risperidone Plus Low Dose of Haloperidol in the Treatment of Schizophrenia |
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| Terminated | 4 | 88 | RoW | risperidone | Kaohsiung Kai-Suan Psychiatric Hospital | Schizophrenia | 07/09 | 10/09 | | |
CAMP, NCT00423878: Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective Disorder |
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| Completed | 4 | 215 | US | Risperidone, Risperdal, Olanzapine, Zyprexa, Quetiapine, Seroquel, Aripiprazole, Abilify | National Institute of Mental Health (NIMH) | Schizophrenia, Schizoaffective Disorder | 10/09 | 03/10 | | |
NCT00418873: Zotepine Versus Risperidone in Aggressive Schizophrenic Patients of Acute Ward |
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| Terminated | 4 | 39 | RoW | Zotepine, Lodopin®, Zoleptil®, Nipolept®, Risperidone, Risperdal® | Astellas Pharma Inc, Astellas Pharma Taiwan, Inc. | Schizophrenia | 12/09 | 12/09 | | |
NCT01010776: A Study to Evaluate Participants Satisfaction, Quality of Life and Effectiveness of Flexible-Dose of Paliperidone Extended Release (ER) in Participants With Schizophrenia, Previously Treated With Risperidone |
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| Completed | 4 | 223 | RoW | Paliperidone Extended Release (ER) | Janssen-Cilag Farmaceutica Ltda. | Schizophrenia | 12/09 | 12/09 | | |
NCT00934635: A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls |
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| Terminated | 4 | 2 | Europe | Paliperidone ER, Oral risperidone, PET Scan | Janssen-Cilag G.m.b.H | Schizophrenia | 12/09 | 12/09 | | |
NCT00932529: Use, Effects and Side-effects of Second-generation Antipsychotics in a Naturalistic Setting |
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| Completed | 4 | 226 | Europe | Olanzapine, Zyprexa, Quetiapine, Seroquel, Risperidone, Risperdal, Ziprasidone, Zeldox, Geodon | University of Bergen | Psychotic Disorders | 01/10 | 01/10 | | |
| Completed | 4 | 37 | Europe | amisulpride and risperidone | Sanofi | Schizophrenia | 01/10 | 01/10 | | |
NCT00946985: 28-30 Month Study Comparing Paliperidone Palmitate With Oral Risperidone for Treating Adults Diagnosed With Schizophrenia Within the Past 5 Years |
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| Terminated | 4 | 163 | US, Canada, Europe, RoW | paliperidone palmitate, oral risperidone | Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 03/10 | 03/10 | | |
NCT00817648: A Study to Evaluate the Efficacy and Safety of Seroquel in Chinese Han Patients With Schizophrenia |
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| Completed | 4 | 120 | RoW | Quetiapine, Seroquel, risperidone, Risperdal | Shanghai Mental Health Center | Schizophrenia | 05/10 | 05/10 | | |
NCT01284959: Different Safety Profile of Risperidone and Paliperidone Extended-release |
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| Completed | 4 | 34 | RoW | risperidone, Rispedal, paliperidone ER, Invega, placebo | Chonbuk National University Hospital, AstraZeneca, Janssen Korea, Ltd., Korea, Korea Otsuka Pharmaceutical Co., Ltd., Sanofi-Synthelabo | Schizophrenia | 07/10 | 12/10 | | |
NCT00245206: Side Effects of Newer Antipsychotics in Older Adults |
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| Completed | 4 | 406 | US | Aripiprazole, Olanzapine, Risperidone, Risperidal | Veterans Medical Research Foundation, National Institute of Mental Health (NIMH) | Schizophrenia, Alzheimer's Disease, Dementia | 10/10 | 10/10 | | |
| Completed | 4 | 30 | Canada | Risperidone | University of British Columbia, Riverview Hospital | Psychosis, Schizophrenia | 10/10 | 10/10 | | |
| Completed | 4 | 87 | Europe | ketamine, ketalar, risperidone, risperdal, saline, placebo risperidone, placebo risperdal | University of Manchester, Cardiff University, King's College London, P1vital Limited | Healthy Volunteers, Schizophrenia | 11/10 | 12/10 | | |
NCT00827840: Paliperidone Extended-Release (ER) Versus Risperidone for Neurocognitive Function in Patients With Schizophrenia |
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| Completed | 4 | 58 | RoW | Paliperidone ER, Invega, Risperidone, Risperdal | Chonnam National University Hospital, Janssen Korea, Ltd., Korea, Ministry of Health, Republic of Korea | Schizophrenia | 02/11 | 02/11 | | |
NCT00417482: Antipsychotic Discontinuation in Alzheimer's Disease |
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| Completed | 4 | 180 | US | risperidone, Risperdal | New York State Psychiatric Institute, National Institute on Aging (NIA), Columbia University | Alzheimer Disease, Psychotic Disorders, Agitation, Aggression | 04/11 | 04/11 | | |
NCT01050582: A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in Children |
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| Completed | 4 | 244 | US, Europe | Risperidone, Other atypical antipsychotic drugs | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Schizophrenia, Bipolar Disorder, Autistic Disorder, Conduct and Other Disruptive Behavior Disorders | 07/11 | 07/11 | | |
NCT00975611: Study of Amantadine for Risperidone Consta or Paliperidone Treated Patients to Decrease Prolactin Elevation |
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| Terminated | 4 | 6 | US | Amantadine Hydrochloride, USP, Symmetrel, Placebo, Symmetrel placebo | David C. Henderson, MD, Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia, Schizoaffective Disorder | 01/12 | 01/12 | | |
| Completed | 4 | 501 | US | iloperidone, Fanapt™ | Novartis | Schizophrenia | 01/12 | 01/12 | | |
NCT02075528: Early Prediction of Clinical Response in Patients With Schizophrenia Treated by Paliperidone ER |
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| Completed | 4 | 41 | RoW | Paliperidone ER, 9-hydroxyrisperidone | Taipei City Hospital, Johnson & Johnson Taiwan Ltd, Taipei Institute of Pathology | Schizophrenia, Schizoaffective Disorder | 05/12 | 07/12 | | |
NCT01193166: Twelve Month Study Comparing Paliperidone Palmitate and Select Oral Antipsychotics in Adults With Schizophrenia Who Have Been Recently Discharged From an Inpatient Psychiatric Hospital |
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| Withdrawn | 4 | 0 | US | paliperidone palmitate, risperidone, olanzapine, aripiprazole, haloperidole, quetiapine, perphenazine, paliperidone | Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 09/12 | 09/12 | | |
NCT01109147 / 2009-017673-38: Comparison of the Effects of Aripiprazole and Risperidone on the Pattern of Brain Activation in Schizophrenic Patients |
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| Completed | 4 | 67 | Europe | Imagery, pharmacogenetic sampling | Qualissima | Schizophrenia, Undifferentiated Type | 01/13 | 05/13 | | |
NCT01592201: A Comparative Study of Patient Satisfaction Between Continued Administration of Previous Antipsychotics Versus Switched Administration to Paliperidone ER in Non-satisfied Patients With Previous Antipsychotic Drug |
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| Terminated | 4 | 13 | RoW | Paliperdidone ER, Aripiprazole, olanzapine and risperidone (Antipsychotics) | Janssen Korea, Ltd., Korea | Schizophrenia | 06/13 | 06/13 | | |
NCT01157351: 15 Month Study for Adults Who Have Been Diagnosed With Schizophrenia and Incarcerated |
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| Completed | 4 | 450 | US | paliperidone, risperidone, haloperidole, perphenazine, aripiprazole, quetiapine, paliperidone palmitate, olanzapine | Janssen Scientific Affairs, LLC | Schizophrenia | 12/13 | 12/13 | | |
IMPACT, NCT00806234: Reducing Weight Gain and Improving Metabolic Function in Children Being Treated With Antipsychotics |
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| Completed | 4 | 127 | US | Aripiprazole or Perphenazine, Abilify, Trilafon, Metformin, Glucophage, Olanzapine, quetiapine, risperidone, ziprasidone, aripiprazole, asenapine, iloperidone, lurasidone, paliperidone, or olanzapine/fluoxetine, Zyprexa, Seroquel, Risperdal, Geodon, Abilify, Saphris, Sycrest, Fanapt, Fanapta, Zomaril, Latuda, Invega, Symbyax | Johns Hopkins University, National Institute of Mental Health (NIMH), University of Maryland, University of North Carolina, Chapel Hill, The Zucker Hillside Hospital | Psychotic Disorders | 03/14 | 03/14 | | |
NCT01458379: Brain Myelination Effects of Paliperidone Palmitate Versus Oral Risperidone in First Episode Schizophrenia |
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| Not yet recruiting | 4 | 50 | US | Paliperidone Palmitate, Risperidone | University of California, Los Angeles, Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 10/14 | 12/15 | | |
NCT00320671: Comparison of Aripiprazole and Risperidone for the Treatment of People With First-Episode Psychosis |
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| Completed | 4 | 198 | US | Aripiprazole, Abilify, Risperidone, Risperdal | Northwell Health, National Institute of Mental Health (NIMH) | Schizophrenia | 12/14 | 12/15 | | |
NCT01670071: A Study to Evaluate the Effect of Oral Paliperidone Extended-Release and Oral Risperidone Immediate-Release on Cognitive Function in Clinically Stable Patients With Schizophrenia |
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| Terminated | 4 | 17 | RoW | Paliperidone extended-release, Paliperidone, Risperidone immediate-release, Risperidone IR | Johnson & Johnson Taiwan Ltd | Schizophrenia | 06/15 | 06/15 | | |
NCT02307396: Evaluation of the Necessity of Long-term Pharmacological Treatment With Antipsychotics in Schizophrenic Patients |
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| Completed | 4 | 21 | Europe | Olanzapine, Amisulpride, Risperidone, Haloperidol, Quetiapine, Perphenazine, Sulpiride, bromperidol, Zuclopenthixol, Thioridazine, Paliperidone, Ziprasidone, Benperidol, Fluspirilene, Pimozide, Perazine, Fluphenazine, Flupentixole, Sertindole | Technische Universität München | Schizophrenia, Schizophrenia and Disorders With Psychotic Features, Schizoaffective Disorders | 06/16 | 06/16 | | |
