risperidone / Generic mfg. |
2006-004891-10: Future strategies for vocational rehabilitation schizophrenia |
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| Ongoing | 4 | 100 | Europe | Ziprasidon, Risperidon, Capsule, hard, Film-coated tablet, Zeldox Hartkapseln, Risperdal | Charité - Universitätsmedizin Berlin | The social implications and long-term consequences of mental disorders regarding sick days at work, unemployment rates and early retirement are considerable. This trial is being conducted to understand whether and how atypical antipsychotic treatment effects long-term job rehabilitation in daily life and 2) and whether, how and which social psychiatric strategies (job consulting, vocational services, work rehabilitation, individual cognitive training) support or amplify these beneficial effects. | | | | |
2007-004857-27: Ventral striatal function in patients with schizophrenia before and under medication with atypical antipsychotics: a comparison of sertindole and risperidone |
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| Ongoing | 4 | 50 | Europe | Sertindol, Risperidon, Tablet, Serdolect, Risperdal | Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich | schizophrenic patients (F20.0, F20.1, F20.2, F20.3, F20.5, F20.6, F20.8, F20.9) and healthy controls | | | | |
ChiCTR-TCC-09000584: Study of clinical efficacy and side effects of risperidone in the treatment of schizophrenics |
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| Completed | 4 | 60 | | Risperidone 2-8mg/d, taken once daily for 6 weeks ;Alimentary control for 1-2 days before sampling (low protein, low fat, no eggs, no meat and no milk) | The Second Xiangya Hospital of Central South University; The Second Xiangya Hospital of Central South University, Director's research fund | Schizophrenia | | | | |
ChiCTR-TNRC-10001112: The study on clinical and biological characters of bipolar depression and the treatment scheme optimizing |
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| Completed | 4 | 640 | | Lithium, Sodium valproate, Lamotrigine, MECT, Sertraline, Citalopram, Escitalopram, venlafaxine, Quetiapine, Olanzapine, Risperidone, sulpiride | Guangzhou Scientific and Technological Bureau, Guangzhou Board of Health; Guangzhou first people's hospital, The Tackling Key Problems of Guangzhou Scientific and Technological Project | bipolar depressive disorder | | | | |
ChiCTR-RNC-09000522: The genetic association study on individual difference of therapeutic effects of antipsychotic medication |
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| Completed | 4 | 900 | | Risperidone 2-6mg/d; Olanzapine 5-20mg/d; Aripiprazole 10-30mg/d | the Sixth Hospital, Peking University; Ministry of Science and Technology of the People′s Republic of China, Ministry of Science and Technology of the People′s Republic of China | schizophrenia | | | | |
| Completed | 4 | 3000 | | Perphenazine 16-64 mg/d (N=250) or Haloperidol 6-20 mg/d (N=250) ;Risperidone 2-6mg/d ;Olanzapine 5-20 mg/d ;Quetiapine 400-750mg/d ;Aripiperazole 10~30 mg/d ;Ziprasidone 80-160 mg/d | The Sixth Hospital / Institute of Mental Health, Peking University; The Ministry of Science and Technology, The National High Technology Research and Development Program of China (863 program) | Schizophrenia | | | | |
2013-001315-71: Dopaminergic genotype of schizophrenic patients and the benefit of adjunctive aripiprazole to risperidone treatment. The effect on hormonal and metabolic measures Perfil dopaminérgico de los pacientes esquizofrénicos que se beneficiarán de la adición de aripiprazol al tratamiento con risperidona/paliperidona. Efecto sobre parámetros hormonales y metabólicos |
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| Ongoing | 4 | 110 | Europe | Tablet, ABILIFY | Mercedes Zumarraga Ortiz, Fundación Vasca de Investigación Sanitaria (Bioef) | schizophrenia Esquizofrenia, schizophrenia Esquizofrenia, Psychiatry and Psychology [F] - Psychological processes [F02] | | | | |
ChiCTR-RNC-09000521: The genetic association study on individual difference of therapeutic effects of antipsychotic medication |
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| Completed | 4 | 2100 | | Risperidone 2-6mg/d; Olanzapine 5-20mg/d; Qutiapine 400-750mg/d; Ziprasidone 80-160 mg/d; Aripiprazole 10-30mg/d; Clozapine 200-600 mg/d; Perphenazine 20-60 mg/d | Sixth Hospital, Peking University; Ministry of Health, China, Ministry of Health, China. | schizophrenia | | | | |
NCT01458379: Brain Myelination Effects of Paliperidone Palmitate Versus Oral Risperidone in First Episode Schizophrenia |
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| Not yet recruiting | 4 | 50 | US | Paliperidone Palmitate, Risperidone | University of California, Los Angeles, Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 10/14 | 12/15 | | |
2014-003651-54: Off-label risperidone in children and adolescents (ORCA): Discontinuation study Off-label risperidon bij kinderen en adolescenten (ORKA): afbouw studie |
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| Ongoing | 4 | 120 | Europe | risperidone, Oral solution | UMCG, ZonMW | no specific condition, we will investigate children who have been using risperidone on an off-label basis for at least one year., no specific condition, we will investigate children who have been using risperidone on an off-label basis for at least one year., Psychiatry and Psychology [F] - Behavioral Disciplines and Activities [F04] | | | | |
2004-004482-15: Hirnaktivierung während Gedächtnisaufgaben bei Patienten mit Schizophrenie unter Behandlung von Ziprasidon oder Risperidon. Eine FMRT-Untersuchung. |
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| Ongoing | 4 | 28 | Europe | Ziprasidon (Zeldox), Risperidon (Risperdal) Tablette, Risperidon (Risperdal) Lösung, Risperidon (Risperdal) Quicklet, Risperidon (Risperdal) Consta, Zeldox, Risperidon (Risperdal), Zeldox, Risperidon (Risperdal) | Universitätsklinikum Aachen, Klinik f. Psychiatrie und Psychotherapie | Patienten mit DSM-IVTR diagnostizierter Schizophrenie | | | | |
2006-005394-22: ESCITALOPRAM MONOTHERAPY COMPARED TO COMBINATION OF ESCITALOPRAM AND RISPERIDONE IN THE TREATMENT OF ACUTE PSYCHOTIC DEPRESSION |
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| Ongoing | 4 | 50 | Europe | Cipralex, Risperdal, Cipralex, Risperdal, Cipralex, Risperdal | Turku university hospital | ICD-10 diagnosis F32.3; psykoottinen masennus, F 33.3; toistuva psykoottinen masennus. | | | | |
2006-007019-25: Pilot open trial of efficacy of Risperidone in Delusional Parasitosis |
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| Ongoing | 4 | 22 | Europe | Risperidone, Risperidone | Barts and the London NHS Trust | Delusional Parasitosis | | | | |
2007-004897-26: Memantine for the Long Term Management of Neuropsychiatric Symptoms in Alzheimer\'s disease - MAIN-AD |
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| Ongoing | 4 | 300 | Europe | Memantine, Risperidone, Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary), Ebixa, Risperdal, Zyprexa, Seroquel, Haloperidol (proprietary) | King\'s College London, North Essex Partnership NHS Foundation Trust | Alzheimer\'s disease | | | | |
2014-003718-10: off-label use of risperidone in people with intellectual disability: A discontinuation study Off-label gebruik van risperidon door mensen met een verstandelijke beperking: een afbouwstudie |
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| Ongoing | 4 | 120 | Europe | Risperidone, | UMCG, ZonMW, Het Zorgondersteuningsfonds | no specific condition, we will investigate people with intellectual disability who have been using risperidone on an off-label basis for at least one year. | | | | |
ChiCTR1900027504: Effect of different dosage of aripiprazole on preventing risperidone-induced hyperprolactinemia: a 8-week, multicenter, randomized, open-label, controlled trial |
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| Completed | 4 | 105 | | Patients treated with risperidone alone for 8 weeks ;Patients treated with risperidone and 5 mg/day aripiprazole for 8 weeks ;Patients treated with risperidone and 10 mg/day aripiprazole for 8 weeks | Shandong Mental Health Center; ShanDong Mental Health Center, Self financing | Schizophrenia | | | | |
2017-002406-12: HAMLETT. Handling Antipsychotic Medication: Long-term Evaluation of Targeted Treatment. A study comparing continuation versus discontinuation/dose reduction of antipsychotic medication in patients remitted after a first episode of psychosis HAMLETT. Handling Antipsychotic Medication: Lange termijn evaluatie van specifiek toegepaste medicatie. Vergelijking tussen het doorgaan met antipsychotische medicatie bij patiënten die hersteld zijn van eerste psychotische episode en vroegtijdig afbouwen/stoppen. |
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| Not yet recruiting | 4 | 512 | Europe | RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE, CID5073, CID135398745, CID5002, CID60795, CID3559, CID5355, CID115237, CID16362, CID213046, CID135398737, CID2159, CID5467, CID60149, CID667467, CIS5311507, Tablet, RISPERIDONE, OLANZAPINE, QUETIAPINE, ARIPIPRAZOLE, HALOPERIDOL, SULPIRIDE, PALIPERIDONE, PIMOZIDE, LURASIDONE, CLOZAPINE, AMISULPRIDE, TIAPRIDE, SERTINDOLE, CHLORPROTHIXENE | University Medical Center Groningen, ZonMw | HAMLETT compares regular treatment guidelines for patients in remission after a first episode of psychosis, namely continuation with antipsychotic medication for at least one year, with early dose reduction/discontinuation. HAMLETT vergelijkt de reguliere behandeling van patiënten in remissie na een eerste psychotische episode zoals beschreven in de richtlijnen, namelijk het continueren van antipsychotica voor minstens 1 jaar, met het vroegtijdig afbouwen/stoppen met medicatie., HAMLETT compares continuation versus early discontinuation of antipsychotic medication in patients who have recovered from their first episode of psychosis. HAMLETT vergelijkt de reguliere behandeling van patiënten die hersteld zijn van een eerste psychose, namelijk minimaal 1 jaar antipsychotica gebruiken, met vroegtijdig afbouwen/stoppn met medicatie, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Not yet recruiting | 4 | 60 | Europe | DM-Aripiprazole, DM-Olanzapine, DM- Quetiapine, DM-Risperidone, Tablet, Aripiprazole, Olanzapine, Quetiapine, Risperidone | Otsuka Pharmaceutical, Otsuka Pharmaceutical | Schizophrenia, Schizoaffective Disorder, or First Episode Psychosis, Schizophrenia, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
ChiCTR1800016707: Effects of Four Antipsychotics on Social Cognitive Function and Metabolism in Patients with Stable Schizophrenia |
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| Recruiting | 4 | 275 | | clozapine ;chlorpromazine ;risperidone ;olanzapine ;no | Mental Health Center of Xuhui District Shanghai; Mental Health Center of Xuhui District Shanghai, Shanghai Municipal Commission of Health and Family Planning | schizophrenia | | | | |
ChiCTR1900022365: Tropisetron plus standard care versus placebo to improvement of cognitive impairment for people with schizophrenia: a randomized controlled trial |
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| Not yet recruiting | 4 | 40 | | Tropisetron combined with Risperidone ;Placebo combined with Risperidone | Beijing An'ding Hospital, Capital Medical University; Beijing An'ding Hospital, Capital Medical University, Beijing Municipal Administration of Hospitals'Youth Programme ' Talent cultivation in Beijing Anding Hospital (subject nova) | schizophrenia | | | | |
| Recruiting | 4 | 2000 | | Risperidone ;Olanzapine ;Aripiperazole ;Quetiapine | 国家科技部; Peking University Sixth Hospital, The Ministry of Science and Technology | Schizophrenia | | | | |
2020-005450-18: Can we improve antipsychotic medication safety by measuring medication blood concentration in children and adolescents. |
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| Ongoing | 4 | 140 | Europe | Tablet, Risperidone | Erasmus MC, Erasmus MC | irritability in autism spectrum disorder, Irritability and aggression in children with autism., Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
2021-003588-85: Individualized care with antipsychotics in patients suffering from schizophrenia spectrum disorders |
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| Not yet recruiting | 4 | 100 | Europe | Olanzapine, Risperidone, Tablet, , Aripiprazole, Olanzapine, Risperidone | UCLouvain, FNRS | Schizophrenia, schizoaffective disorders,psychosis not otherwise specified, and dellusional disorders, psychosis, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
| Recruiting | 4 | 400 | RoW | methylphenidate, fluoxetin, risperidone | The Chaim Sheba Medical Center | Velocardiofacial Syndrome, Williams Syndrome, Fragile X Syndrome | 08/24 | 08/24 | | |
NCT04446234: Atypical Antipsychotics Influence on the Safety of the Heart and Monitoring Indicators Model Building |
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| Not yet recruiting | 4 | 350 | RoW | Risperidone, Aripiprazole, Ziprasidone, Amisulpride, Quetiapine | Shanghai Mental Health Center, Shanghai Jiao Tong University School of Medicine | Schizophrenia | 12/22 | 12/22 | | |
2022-001582-12: Open, multicenter, randomized clinical trial to evaluate the efficacy and safety of aripiprazole vs paliperidone / risperidone using multi-omics data in patients with a first psychotic episode. Ensayo clínico abierto, multicéntrico, aleatorizado para evaluar la eficacia y seguridad de aripiprazol vs paliperidona / risperidona mediante datos multi-ómicos en pacientes con un primer episodio psicótico. |
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| Ongoing | 4 | 244 | Europe | Injection, Abilify Maintena, Xeplion | Consorcio Centro de Investigacion Biomedica en Red (CIBER), Instituto de Salud Carlos III | First episode SZ-spectrum individuals Pacientes con un primer episodio psicótico, First episode SZ-spectrum individuals Pacientes con un primer episodio psicótico, Psychiatry and Psychology [F] - Mental Disorders [F03] | | | | |
NCT03323437: Biomarkers of Conversion Risk and Treatment Response in Early-Stage Schizophrenia |
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| Completed | 4 | 26 | US | Risperidone | Weill Medical College of Cornell University, New York State Psychiatric Institute, Columbia University, National Institute of Mental Health (NIMH) | Schizophrenia Spectrum and Other Psychotic Disorders | 05/23 | 05/23 | | |
ChiCTR2200066865: The strategy of use, efficacy and safety of Rykindo in the treatment of schizophrenia spectrum disorders:a prospective, single-arm, multicenter real-world study |
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| Recruiting | 4 | 300 | | Long-acting injectable risperidone | Beijing Huilongguan Hospital; Beijing Huilongguan Hospital, Corporate Grants | Schizophrenia spectrum disorders | | | | |
NCT06236451: Atypical Antipsychotic-induced Mitochondrial Dysfunction in Patients With Schizophrenia |
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| Recruiting | 4 | 60 | RoW | Aripiprazole, Risperidone | All India Institute of Medical Sciences, Bhubaneswar | Schizophrenia | 08/25 | 09/25 | | |
| Recruiting | 4 | 140 | Europe | Therapeutic Drug Monitoring, Risperidone plasma level | Erasmus Medical Center, Stichting de Merel, ZonMw: The Netherlands Organisation for Health Research and Development | Autism Spectrum Disorder | 05/24 | 05/24 | | |
CASPAR, NCT04940039: A Study to Assess the Treatment of Schizophrenia With Paliperidone Palmitate in Rwandan Healthcare Settings |
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| Completed | 4 | 93 | RoW | Risperidone 3 mg, Paliperidone Palmitate 50 mg eq., R092670, Paliperidone Palmitate 75 mg eq., Paliperidone Palmitate 100 mg eq., Paliperidone Palmitate 150 mg eq., Paliperidone Palmitate 175 mg eq., Paliperidone Palmitate 263 mg eq., Paliperidone Palmitate 350 mg eq., Paliperidone Palmitate 525 mg eq. | Janssen-Cilag International NV | Schizophrenia | 04/24 | 04/24 | | |
NCT04903353: Pragmatic Trial Comparing Weight Gain in Children With Autism Taking Risperidone Versus Aripiprazole |
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| Recruiting | 4 | 350 | US | Comparison of Risperidone and Aripiprazole | Vanderbilt University Medical Center | Weight Gain, Autism Spectrum Disorder, Medication Side Effect | 07/24 | 07/25 | | |
| Terminated | 4 | 5 | US | Lumateperone, Caplyta, Risperidone, Risperdol | University of New Mexico | Psychosis | 02/24 | 02/24 | | |
SchizOMICS, NCT06060886: Multidisciplinary Design to Optimize Schizophrenia Treatment Based on Multi-omics Data and Systems Biology Analysis |
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| Not yet recruiting | 4 | 244 | NA | Aripiprazole, Paliperidone | Consorcio Centro de Investigación Biomédica en Red (CIBER), Instituto de Salud Carlos III | Schizophrenia, Treatment-resistant Schizophrenia, Side Effect, Lipid Metabolism Disorders, Diabetes, NAFLD, Psychosis | 06/25 | 12/25 | | |
| Recruiting | 4 | 524 | US | clozapine, Clozaril, risperidone, Risperdal | University of Texas Southwestern Medical Center, National Institute of Mental Health (NIMH), Beth Israel Deaconess Medical Center, Hartford Hospital, University of Georgia, University of Chicago | Schizophrenia, Schizoaffective Disorder, Bipolar 1 Disorder | 12/25 | 03/26 | | |
NCT05741502: An Exploratory Analysis of Immune and Inflammatory Response Associated With Clozapine |
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| Recruiting | 4 | 60 | US | Clozapine, Antipsychotics,Other (non-Clozapine), Including Olanzapine, Risperidone, Paliperidone, Quetiapine, Aripiprazole, Ziprasidone, Lurasidone, Cariprazine, and all Typical antipsychotics | Ohio State University | Treatment-resistant Schizophrenia | 03/26 | 06/26 | | |
NCT05737511: Efficacy of Hydroxyzine for Patients With Panic Disorder |
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| Not yet recruiting | 4 | 80 | NA | Hydroxyzine, Atarax, Vistaril, Escitalopram Oxalate, citalopram, fluoxetine, fluvoxamine, paroxetine, paroxetine CR, sertraline, venlafaxine XR,, Alprazolam, clomipramine, clonazepam, diazepam, imipramine, lorazepam, mirtazapine, reboxetine, Bupropion SR, divalproex, duloxetine, gabapentin, levetiracetam, milnacipran, moclobemide, olanzapine, phenelzine, quetiapine, risperidone, tranylcypromine | Sultan Qaboos University | Panic Disorder | 12/26 | 12/26 | | |
NCT04478838: "Extended" (Alternate Day) Antipsychotic Dosing |
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| Recruiting | 4 | 120 | Canada | Risperidone, Risperdal, Olanzapine, Zyprexa, Apo-Olanzapine, Sandoz-Olanzapine | Centre for Addiction and Mental Health | Schizophrenia and Related Disorders, Drug Administration Schedule, Drug Therapy, Antipsychotic Agents | 09/27 | 09/28 | | |
2010-021884-34: Relapse prevention in children and adolescents with aggressive anti-social behavior treated with risperidone: a randomized double blind, placebo-controlled, discontinuation study. |
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| Ongoing | 3/4 | 80 | Europe | Risperidone, 6000803, Risperidone, Risperidone | Radboud University Medical Centre Nijmegen, Radboud University, Radboud University Medical Centre Nijmegen, Comisión Europea | Conduct Disorder DSM-IV-TR; 312.8x, APA 2000 | | | | |
2011-000567-26: A randomized double-blind, placebo-controlled study of risperidone in the treatment of aggressive antisocial behavior in youth. |
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| Ongoing | 3/4 | 88 | Europe | Risperidone, 6000803, Risperidone, Risperidone | Radboud University Medical Centre Nijmegen, Radboud University Medical Centre Nijmegen, Comisión Europea | Conduct Disorder DSM-IV-TR; 312.8x¸ APA, 2000 | | | | |