| risperidone / Generic mfg. |
ACTRN12610000954022: An open randomised clinical trial involving Haloperidol, Olanzapine, Quetiapine, Risperidone, and Ziprasidone in first episode never-treated psychosis |
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| Completed | 4 | 150 | | | Lilly, Fundacio La Marato TV3 | Antipsychotic discontinuation in first episode psychosis | | | | |
NCT00253110: A Comparison of Risperidone With Haloperidol in Patients With Schizophrenia and Schizoaffective Disorder |
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| Completed | 4 | 396 | US | risperidone, haloperidol | Janssen, LP | Schizophrenia, Schizoaffective Disorder | | 09/98 | | |
NCT00378183: A Study Comparing Three Strategies to Switch Patients With Schizophrenia or Schizoaffective Disorder to Risperidone After Unsuccessful Treatment With Olanzapine. |
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| Completed | 4 | 120 | US | risperidone | Janssen, LP | Schizoaffective Disorder, Schizophrenia | | 05/02 | | |
NCT00034580: Olanzapine Versus Active Comparator in the Treatment of Bipolar I Disorder |
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| Completed | 4 | 326 | US | olanzapine, risperidone | Eli Lilly and Company | Bipolar Disorder | | 08/02 | | |
NCT00034905: A Comparison of Seroquel vs. Risperidone in Schizophrenia |
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| Completed | 4 | | US | quetiapine fumarate vs risperidone | AstraZeneca | Schizophrenia | 09/02 | 09/02 | | |
NCT00237861: Effectiveness of Atypical Versus Conventional Antipsychotics in Treating Schizophrenia |
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| Completed | 4 | | US | risperidone, olanzapine, quetiapine | Yale University, National Institute of Mental Health (NIMH) | Schizophrenia | 12/02 | | | |
NCT00249171: A Study of Risperidone in Combination With Lorazepam Compared With Standard Therapy for Emergency Treatment of Schizophrenic Patients |
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| Completed | 4 | 226 | Europe | risperidone | Janssen Pharmaceutica N.V., Belgium | Schizophrenia, Psychotic Disorders, Emergency Treatment | | 02/03 | | |
NCT00331825: Risperidone and Olanzapine for the Schizophrenic Patients With Neuroleptic-Induced Acute Dystonia or Parkinsonism |
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| Completed | 4 | 70 | RoW | Risperidone and Olanzapine | Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan, Department of Health | Schizophrenia, Extrapyramidal Syndrome | | 07/03 | | |
NCT00236379: A Study of the Effects of Risperidone and Olanzapine on Blood Glucose (Sugar) in Patients With Schizophrenia or Schizoaffective Disorder |
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| Completed | 4 | 59 | US | Olanzapine, Risperidone | Janssen, LP | Schizophrenia, Diabetes Mellitus | | 08/03 | | |
NCT00621998: Risperidone and Olanzapine for the Schizophrenic Patients With Neuroleptic-Induced Tardive Dyskinesia |
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| Completed | 4 | 60 | RoW | risperidone, olanzapine | Taoyuan Psychiatric Center, Ministry of Health and Welfare, Executive Yuan, R.O.C. Taiwan, Department of Health | Neuroleptic-Induced Tardive Dyskinesia | 12/03 | 06/04 | | |
NCT00485498: Managing Acute Schizophrenia, a Comparison Between Two Atypical Antipsychotics |
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| Completed | 4 | 122 | RoW | Olanzapine Hydrochloride, Risperidone | Eli Lilly and Company | Schizophrenia | | 12/03 | | |
NCT00272584: CARE Study: Improving Treatment for the Most Severely Ill With Schizophrenia |
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| Completed | 4 | 100 | Canada | Risperidone | University of British Columbia | Psychosis, Schizophrenia | | 01/04 | | |
NCT00177567: Treatment of Geriatric Bipolar Mood Disorders: A Pilot Study |
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| Completed | 4 | 60 | US | lithium carbonate, Depakote-ER, risperidone, olanzapine, paroxetine, bupropion, lamotrigine, venlafaxine, tranylcypromine, mirtazapine | University of Pittsburgh | Bipolar Disorder | | 01/04 | | |
NCT00182013: Open-Label Comparative Study of Risperidone Versus Olanzapine Versus Quetiapine for Mania in Children and Adolescents With Bipolar I and Bipolar II Disorder |
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| Completed | 4 | 106 | US | Risperidone, Olanzapine, Quetiapine | Massachusetts General Hospital | Bipolar Spectrum Disorder | 02/04 | | | |
NCT00061802: Efficacy and Safety of Two Atypical Antipsychotics vs. Placebo in Patients With an Acute Exacerbation of Either Schizophrenia or Schizoaffective Disorder |
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| Completed | 4 | 225 | US, Europe, RoW | risperidone, quetiapine | Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Janssen, LP | Schizophrenia, Schizoaffective Disorder | | 02/04 | | |
NCT00308360: Risperidone Alone Vs. Risperidone Plus Valproate in the Treatment of Patients With Schizophrenia and Hostility |
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| Completed | 4 | 46 | US | Risperidone, divalproex | Nathan Kline Institute for Psychiatric Research, Janssen, LP, Research Foundation for Mental Hygiene, Inc. | Schizophrenia | | 04/04 | | |
NCT00181935: Risperidone Versus Olanzapine for Mania in Preschool Children 4 to 6 Years of Age With Bipolar Disorder |
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| Completed | 4 | 40 | US | risperidone (Risperdal), olanzapine (Zyprexa) | Massachusetts General Hospital | Bipolar Disorder, Mania | | 07/04 | | |
NCT00208182: Risperidone in the Treatment of PTSD in Women Survivors of Domestic Abuse and Rape Trauma |
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| Completed | 4 | 20 | US | Risperidone | Creighton University, Janssen, LP | Post-Traumatic Stress Disorder | | 08/04 | | |
| Completed | 4 | | US | Risperidone, Olanzapine, Quetiapine | US Department of Veterans Affairs | Schizophrenia | | 09/04 | | |
NCT00261430: A 2-year Study of Patients With Schizophrenia Who Are Treated With Long-acting Injectable Risperidone. |
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| Completed | 4 | 650 | US | GAIN Acceptance Approach | Janssen, LP | Schizophrenia | | 10/04 | | |
NCT00157378: Optimization of Acute Treatment in First Episode Schizophrenia |
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| Unknown status | 4 | 300 | Europe | Risperidone, Haloperidol | Ludwig-Maximilians - University of Munich, Janssen-Cilag Ltd., German Research Network On Schizophrenia, Department of Psychiatry University of Bonn, Heinrich-Heine University, Duesseldorf, Department of Psychiatry University FU Berlin, University of Göttingen, University of Cologne, Mainz University, University Hospital Tuebingen, Universität Duisburg-Essen, University of Mannheim, University of Jena, Martin-Luther-Universität Halle-Wittenberg, RWTH Aachen University, University of Wuerzburg | Schizophrenia, First-Episode | | 12/04 | | |
| Completed | 4 | 1600 | US | perphenazine, olanzapine, quetiapine, risperidone, ziprasidone, clozapine, fluphenazine decanoate | National Institute of Mental Health (NIMH) | Schizophrenia | | 12/04 | | |
NCT00848432: Risperidone Maintenance Treatment in Schizophrenia |
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| Completed | 4 | 404 | RoW | risperidone, Risperdal | Capital Medical University | Schizophrenia | 12/04 | 12/04 | | |
NCT00297739: Risperidone Augmentation for Treatment-Resistant Aggression in ADHD |
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| Completed | 4 | 25 | US | Risperidone | Armenteros, Jorge L., M.D., P.A., Janssen, LP | Aggression | | 04/05 | | |
NCT00183625: Supported Employment and Skills Training in Conjunction With Pharmacotherapy in Schizophrenia Patients |
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| Completed | 4 | 107 | US | Individual Placement and Support (Supported Employment), Social Skills Training, Olanzapine, Risperidone | University of California, Los Angeles, National Institute of Mental Health (NIMH), US Department of Veterans Affairs | Schizophrenia | 06/05 | 09/06 | | |
NCT00159081: One Year Drug Treatment in First-Episode Schizophrenia |
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| Completed | 4 | 159 | Europe | Haloperidol, Risperidone (drug) | Heinrich-Heine University, Duesseldorf, German Federal Ministry of Education and Research, German Research Network On Schizophrenia, Janssen-Cilag Ltd., University of Bonn, Humboldt-Universität zu Berlin, University of München, University of Göttingen, University of Cologne, Mainz University, University Hospital Tuebingen, Universität Duisburg-Essen, University of Mannheim, University of Jena, Martin-Luther-Universität Halle-Wittenberg, RWTH Aachen University, University of Wuerzburg | Schizophrenia | 06/05 | 06/05 | | |
ACTRN12605000247673: Second generation intervention research in the pre-psychotic phase of illness in schizophrenia and related psychoses |
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| Completed | 4 | 200 | | | Janssen-Cilag Pharmaceuticals, Janssen-Cilag Pharmaceuticals | Schizophrenia and other psychotic disorders | | | | |
NCT00208143: Seroquel Therapy for Substance Use Disorders Comorbid With Schizophrenia |
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| Completed | 4 | 20 | US | Quetiapine, Risperidone | Creighton University, AstraZeneca | Schizophrenia, Schizoaffective Disorder, Substance Abuse, Substance Dependence | | 12/05 | | |
NCT00108368: The Effects of Risperidone and Olanzapine on Thinking |
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| Completed | 4 | | US | Risperidone, Olanzapine | US Department of Veterans Affairs, Janssen, LP | Schizophrenia, Psychotic Disorders | | 03/06 | | |
NCT00178854: Risperidone (Risperdal) Augmentation in Depressed Partial Responders to SRI Treatment |
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| Withdrawn | 4 | 0 | US | Risperidone | Vanderbilt University Medical Center, Janssen, LP | Treatment Resistant Depression | 03/06 | 03/06 | | |
NCT00216554: The Safety and Efficacy of Risperidone as Adjunctive Therapy to Mood Stabilizers in the Long-term Treatment of Bipolar Mania |
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| Completed | 4 | 118 | RoW | risperidone | Janssen Korea, Ltd., Korea | Bipolar Disorder | | 03/06 | | |
NCT00203723: Use of Risperidone in ECT for Treatment Resistant Depression |
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| Terminated | 4 | 45 | US | Risperidone | University of California, Los Angeles, Janssen, LP | Major Depression | | 05/06 | | |
NCT00254241: Safety and Efficacy of Seroquel in First Episode Schizophrenia |
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| Completed | 4 | 80 | Europe | Seroquel and Risperidone | AstraZeneca | Schizophrenia | | 06/06 | | |
| Completed | 4 | 500 | RoW | Aripiprazole, Solian, Olanzapine, Seroquel, Risperidone | Korea Otsuka Pharmaceutical Co., Ltd. | Schizophrenia | 06/06 | 10/07 | | |
NCT00048802: Treatment and Outcome of Early Onset Bipolar Disorder |
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| Completed | 4 | 40 | US | Lithium, Olanzapine, Divalproex, Risperidone, Quetiapine, Ziprasidone, Aripriprazole | Northwell Health, National Institute of Mental Health (NIMH) | Bipolar Disorder | 08/06 | 08/06 | | |
NCT00167479: A Study of Risperidone Monotherapy in Bipolar Anxiety |
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| Completed | 4 | 60 | US | risperidone (Risperdal) | University of South Florida, Janssen, LP | Bipolar Disorder, Panic Disorder, Generalized Anxiety Disorder | | 09/06 | | |
NCT00224315: Clozapine-Augmentation With Ziprasidone or Risperidone, a Randomized, Prospective Trial |
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| Completed | 4 | 24 | Europe | ziprasidone, risperidone | Central Institute of Mental Health, Mannheim | Schizophrenia, Schizoaffective Disorder | | 09/06 | | |
NCT00294255: Risperidone Plus Mood Stabilizer in Treatment of Mixed Mania |
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| Completed | 4 | 45 | US | Risperidone, risperdal | The University of Texas Health Science Center at San Antonio, Janssen, LP | Bipolar Disorder | 10/06 | 10/06 | | |
NCT00203788: Improving Work Outcome in People With Recent-onset Schizophrenia |
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| Completed | 4 | 87 | US | Individual Placement and Support, Workplace Fundamentals Module, Brokered Vocational Rehabilitation, Oral risperidone, Risperdal, Skills training group | University of California, Los Angeles, National Institute of Mental Health (NIMH) | Schizophrenia | 12/06 | 12/06 | | |
NCT00314613: Functional Brain Imaging and Employment in First-Episode Psychotic Patients Treated With Risperdal |
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| Terminated | 4 | 30 | US | Antipsychotic/Risperidone Consta | Duke University, Janssen, LP | Schizophrenia | 12/06 | | | |
NCT00203528: Divalproex ER vs. Risperidone for Bipolar Disorder With Comorbid Substance Use Disorder |
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| Completed | 4 | 30 | US | divalproex sodium ER, risperidone | Tuscaloosa Research & Education Advancement Corporation, Abbott | Substance Abuse, Bipolar Depression | | 02/07 | | |
NCT00289861: Risperidone Augmentation in Patients With Schizophrenia |
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| Completed | 4 | 24 | US | Risperidone, placebo | Massachusetts General Hospital, Stanley Medical Research Institute | Schizophrenia | 03/07 | 03/07 | | |
NCT00232687: A Switch Study of BMS-337039 in Schizophrenic Out-patients |
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| Completed | 4 | 450 | Europe | Aripiprazole, Abilify | Otsuka Pharmaceutical Development & Commercialization, Inc., Otsuka America Pharmaceutical | Schizophrenia | 04/07 | 04/07 | | |
2006-004891-10: Future strategies for vocational rehabilitation schizophrenia |
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| Ongoing | 4 | 100 | Europe | Ziprasidon, Risperidon, Capsule, hard, Film-coated tablet, Zeldox Hartkapseln, Risperdal | Charité - Universitätsmedizin Berlin | The social implications and long-term consequences of mental disorders regarding sick days at work, unemployment rates and early retirement are considerable. This trial is being conducted to understand whether and how atypical antipsychotic treatment effects long-term job rehabilitation in daily life and 2) and whether, how and which social psychiatric strategies (job consulting, vocational services, work rehabilitation, individual cognitive training) support or amplify these beneficial effects. | | | | |
| Completed | 4 | 125 | US | Olanzapine, Risperidone | Northwell Health, National Institute of Mental Health (NIMH), The Zucker Hillside Hospital | Schizophrenia | 05/07 | 05/07 | | |
| Completed | 4 | 116 | US | Risperidone, Risperdal, Olanzapine (enrollment closed in this treatment), Zyprexa, Molindone, Moban | University of North Carolina, Chapel Hill, National Institute of Mental Health (NIMH) | Schizophrenia | 05/07 | 05/07 | | |
NCT00208819: A Comparison of Two Standard Therapies in the Management of Dementia With Agitation |
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| Completed | 4 | 50 | US | risperidone, quetiapine, olanzapine, divalproex | Emory University, Abbott | Senile Dementia, Alzheimer Type, Dementia, Alzheimer Type, Alzheimer Disease, Dementia | | 07/07 | | |
NCT00216632: A Study of Treatment Success in Changing From Olanzapine to Long-acting Injectable Risperidone (RISPERDAL® CONSTA™) |
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| Completed | 4 | 99 | Europe | risperidone | Janssen Pharmaceutica N.V., Belgium | Schizophrenia, Psychotic Disorders | 07/07 | 07/07 | | |
NCT00231335: Efficacy and Safety Study of Escitalopram Augmentation in Treatment Resistant Schizophrenia |
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| Completed | 4 | 30 | US | escitalopram | Emory University, Forest Laboratories | Schizophrenia, Schizoaffective Disorder | | 07/07 | | |
NCT00287820: Comparative Effects of Chronic Treatment With Olanzapine and Risperidone on Glucose and Lipid Metabolism |
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| Completed | 4 | 46 | US | Olanzapine, ayprexa, olanzapine, zyprexa, risperidone, riperidal | Nathan Kline Institute for Psychiatric Research, Eli Lilly and Company | Schizophrenia, Diabetes, Metabolic Syndrome, Hyperglycemia | | 09/07 | | |
| Completed | 4 | 48 | RoW | Risperidone, Respidon, risperidone, Citalopram, Citopam, Placebo | National Institute of Mental Health and Neuro Sciences, India | Schizophrenia, Negative Symptoms | 09/07 | 09/07 | | |
NCT00204347: Effective Measurement of Risperidone Treatment Outcome for Persons With Borderline Personality Disorder |
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| Completed | 4 | 20 | US | risperidone | University of Alabama at Birmingham, Janssen Pharmaceutica | Borderline Personality Disorder | 10/07 | 10/07 | | |
NCT00325689: Aripiprazole Used as Dual Therapy in the Treatement of Patients With Chronic Stable Schizophrenia or Schizoaffective Disorder. |
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| Completed | 4 | 323 | US | Quetiapine or Risperidone + Aripiprazole, Abilify, Quetiapine or Risperidone + placebo | Otsuka Pharmaceutical Development & Commercialization, Inc., Otsuka America Pharmaceutical | Schizophrenia, Schizoaffective Disorder | 10/07 | 10/07 | | |
NCT00056498: Risperidone Treatment in Schizophrenia Patients Who Are Currently Taking Clozapine |
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| Completed | 4 | 65 | US | Placebo, Risperdal, Risperidone | University of Maryland, Baltimore, National Institute of Mental Health (NIMH), Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 12/07 | 12/07 | | |
| Unknown status | 4 | 80 | US | atypical antipsychotics:oral vs. long-acting route, Family Psychoeducation | State University of New York - Downstate Medical Center, Janssen, LP | Schizophrenia | | 12/07 | | |
ACPIOS, NCT00654576: Effectiveness of Antipsychotic Combination With Psychosocial Intervention on Outcome of Patients With Schizophrenia |
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| Completed | 4 | 1400 | RoW | Chlorpromazine, Sulpiride, Clozapine, Olanzapine, Risperidone, Quetiapine, Aripitrazole, psychosocial intervention | Central South University, Shanghai Mental Health Center, Sichuan University, Capital Medical University, Nanjing Medical University, Jiangxi Mental Hospital, Hunan Mental Hospital, Guangzhou Mental Hospital, Chongqing Metal Institute, Henan Mental Hospital | Schizophrenia | 12/07 | 12/07 | | |
NCT00337662: Efficacy Study of Early Onset of Antipsychotic Drug Action in Schizophrenia |
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| Completed | 4 | 628 | US, RoW | olanzapine, LY170053, Zyprexa, risperidone | Eli Lilly and Company | Schizophrenia, Schizoaffective Disorder, Schizophreniform Disorder | 12/07 | 12/07 | | |
2007-004857-27: Ventral striatal function in patients with schizophrenia before and under medication with atypical antipsychotics: a comparison of sertindole and risperidone |
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| Ongoing | 4 | 50 | Europe | Sertindol, Risperidon, Tablet, Serdolect, Risperdal | Department of Psychiatry and Psychotherapy, Ludwig-Maximilians-University Munich | schizophrenic patients (F20.0, F20.1, F20.2, F20.3, F20.5, F20.6, F20.8, F20.9) and healthy controls | | | | |
NCT00626613: The Relationship Between Risperdal Treatment and Quality of Life in Patients With Alzheimer's Disease and Behavioural and Psychological Symptoms of Dementia (BPSD) |
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| Unknown status | 4 | | RoW | Risperdal,reminyl | Jinan Mental Hospital, Johnson & Johnson | Dementia, Alzheimer's Disease | | | | |
NCT00140166: Treatment of Acute Schizophrenia With Vitamin Therapy |
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| Completed | 4 | 55 | RoW | niacinamide, pyridoxine, ascorbate | Beersheva Mental Health Center, Supported by a Hilton Family Foundation grant to, International Schizophrenia Foundation | Acute Schizophrenia | | 05/08 | | |
NCT00190749: Safety Study of Olanzapine and a Comparator in Patients With Schizophrenia and Schizoaffective Disorder |
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| Completed | 4 | 130 | US | olanzapine, LY170053, Zyprexa, risperidone | Eli Lilly and Company | Schizophrenia, Schizoaffective Disorder | 06/08 | 06/08 | | |
NCT00535132: Study to Measure Drug Satisfaction of Patients With Schizophrenia After Switching From Risperidone to Paliperidone |
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| Completed | 4 | 201 | US, Europe, RoW | Oral Risperidone, Paliperidone ER | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Schizophrenia | 07/08 | 07/08 | | |
NCT00498004: Quality of Life (QOL) in Female Patient With Schizophrenia |
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| Terminated | 4 | 100 | RoW | Quetiapine, Risperidone | Inje University | Schizophrenia | 09/08 | 09/08 | | |
NCT00206102: A Study of the Cataractogenic Potential of Seroquel and Risperdal in the Treatment of Participants With Schizophrenia or Schizoaffective Disorder |
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| Completed | 4 | 1098 | US | quetiapine fumarate, Seroquel, ICI 204,636, risperidone | AstraZeneca | Schizophrenia, Schizoaffective Disorder | 10/08 | 10/08 | | |
BEST, NCT00712270: Best Event Schizophrenia Trial--A Randomized Double-Blind Trial of Aripiprazole and Risperidone in Schizophrenia |
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| Terminated | 4 | 21 | US | Aripiprazole, Abilify, Risperidone, Risperdal | Kettering Health Network | Schizophrenia | 12/08 | 11/10 | | |
NCT00299702: Evaluation of Effectiveness of Risperdal® Consta® Compared to Abilify® Over a Two-year Period in Patients With Schizophrenia |
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| Completed | 4 | 355 | US | Abilify, Risperidal Consta | Johnson & Johnson Pharmaceutical Research & Development, L.L.C., Janssen, LP | Schizophrenia, Psychotic Disorders | 01/09 | 01/09 | | |
| Completed | 4 | 50 | US | Risperdal (risperidone) Consta, Risperidone long-acting injectible, Treatment as usual, Usual care | Vanderbilt University, Ortho-McNeil Janssen Scientific Affairs, LLC | Bipolar Disorder | 02/09 | 02/09 | | |
NCT00508157 / 2007-001217-42: A Phase 4 Study to Assess the Effects of Aripiprazole Versus Other Atypical Antipsychotics in the Treatment of Schizophrenic Patients With Metabolic Syndrome |
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| Terminated | 4 | 125 | Europe, RoW | Aripiprazole, Abilify, BMS-337039, Continued Antipsychotic (Risperidone or Quetiapine or Olanzapine) | Bristol-Myers Squibb, Otsuka America Pharmaceutical | Metabolic Syndrome, Schizophrenia | 03/09 | 03/09 | | |
NCT00622011: Risperidone and Zotepine in the Treatment of Delirium |
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| Terminated | 4 | 5 | RoW | Risperidone and Zotepine for delirium, risperidone( Risperdal), zotepine( Lodopine) | Changhua Christian Hospital | Delirium | 03/09 | 03/09 | | |
NCT00859872: Efficacy and Safety of Risperidone Oral Solution Combination Clonazepam Versus Haloperidol Intramuscular (IM) Injection for Treatment of Acute Psychotic Agitation in Schizophrenia |
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| Completed | 4 | 198 | RoW | risperidone oral solution, haloperidol | Central South University, Wuhan Mental Health Institute, Capital Medical University, Shanghai Mental Health Center, Guangzhou Mental Hospital, Chongqing Mental Hospital | Schizophrenia | 03/09 | 03/09 | | |
NCT00998608: Comparison of the Efficacy and Safety of Risperidone Versus Risperidone Plus Low Dose of Haloperidol in the Treatment of Schizophrenia |
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| Terminated | 4 | 88 | RoW | risperidone | Kaohsiung Kai-Suan Psychiatric Hospital | Schizophrenia | 07/09 | 10/09 | | |
CAMP, NCT00423878: Comparison of Antipsychotics for Metabolic Problems in Schizophrenia or Schizoaffective Disorder |
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| Completed | 4 | 215 | US | Risperidone, Risperdal, Olanzapine, Zyprexa, Quetiapine, Seroquel, Aripiprazole, Abilify | National Institute of Mental Health (NIMH) | Schizophrenia, Schizoaffective Disorder | 10/09 | 03/10 | | |
ChiCTR-TCC-09000584: Study of clinical efficacy and side effects of risperidone in the treatment of schizophrenics |
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| Completed | 4 | 60 | | Risperidone 2-8mg/d, taken once daily for 6 weeks ;Alimentary control for 1-2 days before sampling (low protein, low fat, no eggs, no meat and no milk) | The Second Xiangya Hospital of Central South University; The Second Xiangya Hospital of Central South University, Director's research fund | Schizophrenia | | | | |
NCT00338949: Ziprasidone for Improving Insulin Sensitivity in People With Schizophrenia Who Are at Risk for Diabetes |
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| Completed | 4 | 77 | US | Switch, ziprasidone, Control, risperidone, olanzapine | Veterans Medical Research Foundation, National Institute of Mental Health (NIMH), Pfizer | Schizophrenia, Metabolic Syndrome X, Insulin Resistance | 12/09 | 12/09 | | |
NCT00418873: Zotepine Versus Risperidone in Aggressive Schizophrenic Patients of Acute Ward |
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| Terminated | 4 | 39 | RoW | Zotepine, Lodopin®, Zoleptil®, Nipolept®, Risperidone, Risperdal® | Astellas Pharma Inc, Astellas Pharma Taiwan, Inc. | Schizophrenia | 12/09 | 12/09 | | |
NCT01010776: A Study to Evaluate Participants Satisfaction, Quality of Life and Effectiveness of Flexible-Dose of Paliperidone Extended Release (ER) in Participants With Schizophrenia, Previously Treated With Risperidone |
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| Completed | 4 | 223 | RoW | Paliperidone Extended Release (ER) | Janssen-Cilag Farmaceutica Ltda. | Schizophrenia | 12/09 | 12/09 | | |
NCT00934635: A Positron-Emission-Tomography (PET) Study to Measure the Blockade of Dopamine Receptors (D2) in Specific Areas of the Brain in Relation to the Plasma Concentrations of Paliperidone Extended Release (ER) and Oral Risperidone in Schizophrenia Patients and Healthy Controls |
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| Terminated | 4 | 2 | Europe | Paliperidone ER, Oral risperidone, PET Scan | Janssen-Cilag G.m.b.H | Schizophrenia | 12/09 | 12/09 | | |
NCT00932529: Use, Effects and Side-effects of Second-generation Antipsychotics in a Naturalistic Setting |
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| Completed | 4 | 226 | Europe | Olanzapine, Zyprexa, Quetiapine, Seroquel, Risperidone, Risperdal, Ziprasidone, Zeldox, Geodon | University of Bergen | Psychotic Disorders | 01/10 | 01/10 | | |
NCT00305474: Identification and Treatment of the Liability to Develop Schizophrenia |
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| Unknown status | 4 | 100 | RoW | Risperidone | Central South University, Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 01/10 | | | |
| Completed | 4 | 37 | Europe | amisulpride and risperidone | Sanofi | Schizophrenia | 01/10 | 01/10 | | |
2008-003340-11: The “therapeutic window” of the "atypical” antipsychotic paliperidone ER - A Positron Emission Tomography study with [18F]fallypride as the radiotracer |
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| Terminated | 4 | 34 | Europe | [18F]fallypride, R076477, Injection*, Prolonged-release tablet, Film-coated tablet, INVEGA 6 mg Retardtabletten, INVEGA 9 mg Retardtabletten, RISPERDAL 3 mg, RISPERDAL 4 mg | JANSSEN-CILAG GmbH | subchronic schizophrenia | | | | |
NCT00946985: 28-30 Month Study Comparing Paliperidone Palmitate With Oral Risperidone for Treating Adults Diagnosed With Schizophrenia Within the Past 5 Years |
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| Terminated | 4 | 163 | US, Canada, Europe, RoW | paliperidone palmitate, oral risperidone | Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia | 03/10 | 03/10 | | |
EscBPSD, NCT01119638: Escitalopram Treatment for BPSD in Alzheimer's Disease in Comparison to Risperidone |
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| Completed | 4 | 40 | RoW | Escitalopram, Cipralex, Risperidone, Risperdal | Abarbanel Mental Health Center | Agitation, Psychosis, Alzheimer's Disease | 04/10 | 05/10 | | |
NCT00817648: A Study to Evaluate the Efficacy and Safety of Seroquel in Chinese Han Patients With Schizophrenia |
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| Completed | 4 | 120 | RoW | Quetiapine, Seroquel, risperidone, Risperdal | Shanghai Mental Health Center | Schizophrenia | 05/10 | 05/10 | | |
NCT00937261: Contrasting the Brain Effects of Risperidone and Invega With Functional Magnetic Resonance Imaging (fMRI) and Positron Emission Tomography (PET) Scanning |
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| Unknown status | 4 | 96 | US | Risperidone, Risperdal, Paliperidone, Invega | University of California, Irvine, Janssen, LP | Schizophrenia | 07/10 | 01/11 | | |
NCT01284959: Different Safety Profile of Risperidone and Paliperidone Extended-release |
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| Completed | 4 | 34 | RoW | risperidone, Rispedal, paliperidone ER, Invega, placebo | Chonbuk National University Hospital, AstraZeneca, Janssen Korea, Ltd., Korea, Korea Otsuka Pharmaceutical Co., Ltd., Sanofi-Synthelabo | Schizophrenia | 07/10 | 12/10 | | |
NCT00245206: Side Effects of Newer Antipsychotics in Older Adults |
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| Completed | 4 | 406 | US | Aripiprazole, Olanzapine, Risperidone, Risperidal | Veterans Medical Research Foundation, National Institute of Mental Health (NIMH) | Schizophrenia, Alzheimer's Disease, Dementia | 10/10 | 10/10 | | |
| Completed | 4 | 30 | Canada | Risperidone | University of British Columbia, Riverview Hospital | Psychosis, Schizophrenia | 10/10 | 10/10 | | |
| Completed | 4 | 87 | Europe | ketamine, ketalar, risperidone, risperdal, saline, placebo risperidone, placebo risperdal | University of Manchester, Cardiff University, King's College London, P1vital Limited | Healthy Volunteers, Schizophrenia | 11/10 | 12/10 | | |
NCT00352339: The New Strategy for Pharmacological Treatment in People With Schizophrenia |
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| Unknown status | 4 | 90 | RoW | Rispridoen and Aripiprazole, Risperidne, Abilify, abilify is a generic name of aripiprazole | Inje University | Schizophrenia | 12/10 | 12/10 | | |
| Completed | 4 | 149 | Europe | Risperidone, ATC code N05AX 08, Escitalopram, ATC code N06AB 10, Citalopram, ATC code N06AB 04, Sertraline, ATC code N06AB 06, Paroxetine, ATC code N06AB 05 | Sykehuset Innlandet HF, Ullevaal University Hospital, Eikertun Nursing Home, University of Bergen, Innlandet Hospital Trust, Sanderud, Innlandet Hospital Trust, Reinsvoll, Diakonhjemmet Hospital, Sykehuset Telemark, The Nordmøre and Romsdal Hospital Trust, Songdalstunet Nursing Home, Sykehuset Buskerud HF, Kroken Nursing Home, Tromsø, Kløveråsen, Bodø, Bjørgene Omsorgssenter, Haugesund, Alesund Hospital | Dementia | 12/10 | 12/10 | | |
ChiCTR-TNRC-10001112: The study on clinical and biological characters of bipolar depression and the treatment scheme optimizing |
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| Completed | 4 | 640 | | Lithium, Sodium valproate, Lamotrigine, MECT, Sertraline, Citalopram, Escitalopram, venlafaxine, Quetiapine, Olanzapine, Risperidone, sulpiride | Guangzhou Scientific and Technological Bureau, Guangzhou Board of Health; Guangzhou first people's hospital, The Tackling Key Problems of Guangzhou Scientific and Technological Project | bipolar depressive disorder | | | | |
ChiCTR-RNC-09000522: The genetic association study on individual difference of therapeutic effects of antipsychotic medication |
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| Completed | 4 | 900 | | Risperidone 2-6mg/d; Olanzapine 5-20mg/d; Aripiprazole 10-30mg/d | the Sixth Hospital, Peking University; Ministry of Science and Technology of the People′s Republic of China, Ministry of Science and Technology of the People′s Republic of China | schizophrenia | | | | |
NCT00827840: Paliperidone Extended-Release (ER) Versus Risperidone for Neurocognitive Function in Patients With Schizophrenia |
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| Completed | 4 | 58 | RoW | Paliperidone ER, Invega, Risperidone, Risperdal | Chonnam National University Hospital, Janssen Korea, Ltd., Korea, Ministry of Health, Republic of Korea | Schizophrenia | 02/11 | 02/11 | | |
| Completed | 4 | 144 | US | risperidone, Risperdal, olanzapine, Zyprexa, aripiprazole, Abilify | Washington University School of Medicine, National Institute of Mental Health (NIMH) | Aggression, Attention Deficit-Hyperactivity, Oppositional Defiant Disorder, Pervasive Development Disorders, Bipolar Disorder | 03/11 | 07/11 | | |
NCT00417482: Antipsychotic Discontinuation in Alzheimer's Disease |
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| Completed | 4 | 180 | US | risperidone, Risperdal | New York State Psychiatric Institute, National Institute on Aging (NIA), Columbia University | Alzheimer Disease, Psychotic Disorders, Agitation, Aggression | 04/11 | 04/11 | | |
NCT01050582: A Study to Evaluate the Safety and the Effects of Risperidone Compared With Other Atypical Antipsychotic Drugs on the Growth and Sexual Maturation in Children |
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| Completed | 4 | 244 | US, Europe | Risperidone, Other atypical antipsychotic drugs | Johnson & Johnson Pharmaceutical Research & Development, L.L.C. | Schizophrenia, Bipolar Disorder, Autistic Disorder, Conduct and Other Disruptive Behavior Disorders | 07/11 | 07/11 | | |
NCT00480844: Comparison of Cognitive Functions of Schizophrenic Patients Treated With Sertindole Versus Risperidone |
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| Unknown status | 4 | 60 | RoW | Sertindole, Serdolect, Risperidone, Rispond, Risperdal, Risperidex | Sheba Medical Center | Schizophrenia | 10/11 | | | |
| Completed | 4 | 3000 | | Perphenazine 16-64 mg/d (N=250) or Haloperidol 6-20 mg/d (N=250) ;Risperidone 2-6mg/d ;Olanzapine 5-20 mg/d ;Quetiapine 400-750mg/d ;Aripiperazole 10~30 mg/d ;Ziprasidone 80-160 mg/d | The Sixth Hospital / Institute of Mental Health, Peking University; The Ministry of Science and Technology, The National High Technology Research and Development Program of China (863 program) | Schizophrenia | | | | |
NCT00975611: Study of Amantadine for Risperidone Consta or Paliperidone Treated Patients to Decrease Prolactin Elevation |
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| Terminated | 4 | 6 | US | Amantadine Hydrochloride, USP, Symmetrel, Placebo, Symmetrel placebo | David C. Henderson, MD, Ortho-McNeil Janssen Scientific Affairs, LLC | Schizophrenia, Schizoaffective Disorder | 01/12 | 01/12 | | |
