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46 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Infertility
ChiCTR-TRC-12002059: Study on effects of transcutaneous acupoint electrical stimulation at different acupoints on pregnant outcomes in women undergoing In Vitro Fertilization Pre-Embryo Transfer

Completed
2
800
 
blank ;TEAS in 4 acupoints in limbs ;TEAS in 4 acupoints in abdomen ;TEAS in 4 acupoints in abdomen
Neuroscience Research Institute, Peking University; National Natural Science Foundation of China, National Natural Science Foundation of China
infertility
 
 
2010-020196-23: A phase II, multicentre, open label, prospective, interventional study to evaluate the sperm DNA fragmentation in idiopathic male infertility before and after treatment with Gonal-f PEN 900 IU.

Ongoing
2
120
Europe
GONAL F 150, GONAL F 150
MERCK SERONO SPA
Idiophatic male infertility
 
 
2016-003993-42: Clinical study to investigate the effectiveness and safety of PKB171 in couples with infertility due to reduced sperm mobility who wish to conceive. Ensayo clínico para investigar la eficacia y la seguridad de PKB171 en parejas con infertilidad debido a una reducción en la mobilidad del esperma, que desean concebir.

Ongoing
2
72
Europe
Gel PKB171, Vaginal gel
Prokrea BCN S.L., Prokrea BCN S.L.
Asthenozoospermia Astenozoospermia, Infertility due to reduced sperm mobility. Infertilidad debida a movilidad reducida del esperma., Diseases [C] - Male diseases of the urinary and reproductive systems [C12]
 
 
2016-002385-31: Treatment of abnormal vaginal flora in patients attending in vitro fertilization treatment

Ongoing
2
333
Europe
Clindamycin "Alternova", Lactin-V, 37826, Capsule, hard, Vaginal delivery system, Clindamycin "Alternova"
Professor Peter Humaidan, The Fertility Clinic Skive, Statens Serum Institut, Aarhus University, Osel. inc
Infertility, infertile women attending in vitro fertilization treatment, Diseases [C] - Bacterial Infections and Mycoses [C01]
 
 
NCT03762967: Autologous Adipose-Derived Adult Stromal Vascular Cell Administration for Male Patients With Infertility

Enrolling by invitation
2
40
RoW
Lipoaspiration and SVF introduction., Standard therapy., healthy diet, physical exertion eliminate. hormone therapy.
State-Financed Health Facility "Samara Regional Medical Center Dinasty"
Azoospermia, Oligozoospermia
12/20
12/21
NCT03030196 / 2016-003546-84: Denosumab and Male Infertility: a RCT

Completed
2
95
Europe
Denosumab, Prolia
Martin Blomberg Jensen
Infertility, Male
01/21
05/23
NCT05143723: Luteal Phase Support With Daily Administration of Gonadotropin-releasing Hormone Agonist Compared to Progesterone/Estradiol in IVF/ICSI Cycles With Ovulation Triggering With GnRH-a

Active, not recruiting
2
102
RoW
Gonadotropin-releasing hormone agonist
Kuban State Medical University
Infertility
04/21
06/22
ChiCTR1900026669: The Clinical Observation for Chinese Medicine and Moxibustion in the treatment of low testosterone Oligoasthenozoospermia

Not yet recruiting
2
90
 
Moxibustion at Shenque (RN8), Guanyuan (RN4), Shenshu (BL23) and Sanyinjiao (SP6) ;Take 'Qizhenziyin-Mixture', 25 ml Oral liquid, tid ;Take 'Qizhenziyin-Mixture', 25 ml Oral liquid, tid., Moxibustion at Shenque (RN8), Guanyuan (RN4), Shenshu (BL23) and Sanyinjiao (SP6)
Longhua Hospital Shanghai University of Traditional Chinese Medicine; Longhua Hospital Shanghai University of Traditional Chinese Medicine, Shanghai Committee of Science and Technology, China
male infertility
 
 
2021-003451-42: FITMI - First In Treating Male Infertility

Not yet recruiting
2
282
Europe
Denosumab, Solution for injection, Prolia (Denosumab)
Dept. of Growth and Reproduction, BioInnation Institute, Rigshospitalet, Vaekstfonden, Novo Nordisk Fonden, Forskningsraadet for sundhed og sygdom
Male infertility, Poor semen quality, Diseases [C] - Male diseases of the urinary and reproductive systems [C12]
 
 
2021-004254-37: A trial to compare efficacy and safety of follitropin delta versus placebo (inactive treatment) in the treatment of men with idiopathic infertility (unexplained reduction of semen quality).

Ongoing
2
400
Europe
Solution for injection in pre-filled pen, REKOVELLE
Ferring Pharmaceuticals A/S, Ferring Pharmaceuticals A/S
Idiopathic male infertility (including oligoasthenozoospermia), Unexplained reduction of semen quality in men, Diseases [C] - Male diseases of the urinary and reproductive systems [C12]
 
 
NCT05105724: Autologous Platelet-rich Plasma to Improve Responsiveness and Embryo Quality in Patients With Poor Ovarian Response

Recruiting
2
50
RoW
PRP
Nanjing University
Infertility
07/22
07/22
2022-000753-80: Clinical research study to learn about the effect and safety of different doses of FE 999302 when given as a single dose for final development of the eggs after ovarian stimulation Estudio de investigación clínica para conocer el efecto y la seguridad de diferentes dosis de FE 999302 cuando se administra como dosis única para el desarrollo final de los óvulos después de la estimulación ovárica

Ongoing
2
500
Europe
NOVAREL, OVITRELLE, FE 999302, FE 999086, Solution for injection, Powder and solvent for solution for injection, Solution for injection in pre-filled pen, Solution for injection in pre-filled syringe, NOVAREL, OVITRELLE
Ferring Pharmaceuticals A/S, Ferring Pharmaceuticals A(S
Infertility Infertilidad, Infertility Infertilidad, Body processes [G] - Reproductive physiologi cal processes [G08]
 
 
NCT05804149: Effect of Acupuncture and Low Caloric Diet on Primary Hypothyroidism and Irregular Menstruation in Infertile Women

Completed
2
60
RoW
acupuncture, Thyroxine, levothyroxine, low caloric diet
Cairo University
Primary Hypothyroidism, Acupuncture, Irregular Menstruation, PCO
09/22
02/23
PROGEX, NCT03701490 / 2018-002897-27: Prolutex in Frozen Embryo Transfer Cycles at the Blastocyst Stage

Completed
2
213
Europe
Progesterone subcutaneous, Progesterone Vaginal Product
IBSA Institut Biochimique SA
Infertility
09/22
12/22
NCT05200663: Efficacy Comparison of Tamoxifen and Tamoxifen With Antioxidants on Semen Quality of Male With Idiopathic Infertility

Recruiting
2
110
RoW
Tab Tamoxifen 10 mg, Group A, Tab Tamoxifen 10mg,Cap vitamin E 400mg, Group B
Sharif Medical Research Center
Oligoasthenoteratozoospermia, Male Infertility
10/22
10/22
NCT05847257: Impact of Co Enzyme Q10 as Adjuvant Therapy to Letrozole on Spermiogram

Completed
2
74
RoW
Letrozole tablets, Coenzyme Q10 table
Al-Mustansiriyah University, Al-Nahrain University
Male Reproductive Problem, Infertility, Male
10/22
10/22
ChiCTR2000038030: Phase II/III clinical trial of recombinant human follicle-stimulating hormone -CTP fusion protein injection in patients undergoing assisted reproductive technology (ART)

Recruiting
2
374
 
recombinant human follicle-stimulating hormone -CTP fusion protein injection +Recombinant Human Follitropin Alfa Solution for Injection ;Recombinant Human Follitropin Alfa Solution for Injection
The First Affiliated Hospital of Anhui Medical University; Suzhou Centergene Pharmaceuticals Co., Ltd., Fully self-raised
infertility
 
 
2022-003879-42: randomized, controlled, double-blind clinical trial evaluating the effect of METformin treatment on endometrial function in women diagnosed with Idiopathic Infertility Badanie efektywności metforminy w leczeniu idiopatycznej niepłodności

Not yet recruiting
2
200
Europe
Tablet, Glucophage
Medical Univeristy of Bialystok, Medical University of Bialystok
Potential causes of idiopathic infertility include in particular: abnormal function of the endometrium, including implantation disorders and immunological abnormalities, genetic abnormalities and the functioning of reproductive cells and embryos, functional abnormalities of reproductive cells and embryos, dysfunctions and discreet anatomical anomalies of the fallopian tubes transport of reproductive cells and embryos. Potencjalne podłoże niepłodności idiopatycznej wymienia się w szczególności: nieprawidłową funkcję endometrium, w tym zaburzenia implantacji oraz nieprawidłowości immunologiczne, nieprawidłowości genetyczne i funkcjonowanie komórek rozrodczych i zarodków, nieprawidłowości funkcjonalne komórek rozrodczych i zarodków, zaburzenia funkcji oraz dyskretne anomalie anatomiczne jajowodów (pomimo zachowanej drożności) zaburzające transport komórek rozrodczych oraz zarodków., Idiopathic infertility is diagnosed after all other medically known symptoms of infertility are excluded. This category includes 5 - 10% of all infertile couples. Niepłodność diopatyczną rozpoznaje się po wykluczeniu wszystkich innych medycznie znanych objawów niepłodności. Ta kategoria obejmuje 5 - 10% wszystkich niepłodnych par., Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13]
 
 
NCT04938011: A Randomized Controlled Study of Prolonging the Time of Progesterone Supplementation to Improve the Pregnancy Outcome of Single Day 6 Blastocyst Transfer of Freeze-thaw Cycle

Not yet recruiting
2
900
RoW
progesterone
Nanjing University
Infertility
06/23
06/24
EFFECT, NCT04039204: Elagolix for Fertility Enhancement Clinical Trial

Completed
2
10
US
Elagolix, Orilissa, Oral Contraceptive
Wake Forest University Health Sciences, University of North Carolina, Chapel Hill, Stanford University
Endometriosis, Unexplained Infertility
08/23
08/23
NCT05166746: The Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal Microbiota

Recruiting
2
333
Europe
Clindamycin, LACTIN-V, Placebo
Peter Humaidan
Bacterial Vaginoses, Infertility, Female
10/23
10/23
OXOART2, NCT05076032 / 2021-000001-25: Phase II Clinical Trial to Evaluate the Ongoing Pregnancy Rate With OXO-001 in IVF/ICSI With Donor Oocytes.

Completed
2
408
Europe, RoW
OXO-001, Placebo
OXOLIFE
Infertility, Female, Infertility
08/23
12/23
Doubtrig, NCT06146413: Triggering Oocyte Maturation in Normoresponders Using Double Trigger or HCG Trigger

Not yet recruiting
2
150
RoW
Double trigger, Augmented trigger, HCG trigger, Conventional trigger
Bedaya Hospital
Infertility
03/25
12/25
PRO_ART, NCT03727971: Treatment With the Anti-IgE Monoclonal Antibody Omalizumab in Women With Asthma Undergoing Fertility Treatment. - A Proof of Concept Study.

Active, not recruiting
2
66
Europe
Omalizumab Injection, NaCl
Rigshospitalet, Denmark, Novartis, Hvidovre University Hospital, Herlev Hospital, Zealand University Hospital
Asthma, Infertility, Female
12/23
12/29
NCT05290558: The Therapeutic Effects of Bu Shen Yi Jing Pill on Semen Quality in Sub Fertile Males: a Randomized Controlled Trial

Recruiting
2
200
RoW
Bu Shen Yi Jing Pill, BSYJ Pill, Placebo Drug, Control drug
KK Women's and Children's Hospital
Male Infertility, Infertility, Traditional Chinese Medication (TCM), Reproductive Issues
12/23
12/24
NCT04955574: Probiotic and Antibiotic Therapies in Women With Unexplained Infertility

Withdrawn
2
39
NA
SH-DS01 + Antibiotic Placebo, SH-DS01 + Metronidazole, Probiotic Placebo + Antibiotic Placebo
McMaster University, One Fertility
Unexplained Infertility, Endometriosis
01/24
12/24
NCT06212102: Dydrogesterone Versus GnRH Antagonist in Poor Responders Undergoing Double Ovarian Stimulation

Not yet recruiting
2
120
RoW
Progestin primed ovarian stimulation, GnRH antagonist
Bedaya Hospital
Infertility
03/26
12/26
ChiCTR2300068556: Linggui Yangyuan Paste for patients with male infertility: a study protocol for a multicenter, double-blind, double-dummy, randomized controlled trial

Not yet recruiting
2
162
 
Ling-Gui-Yang-Yuan Gel and Wu-Zi-Yan-Zong oral solution mimetics ;Wu-Zi-Yan-Zong oral solution and Ling-Gui-Yang-Yuan Gel mimetics
Xiyuan Hospital of China Academy of Chinese Medical Sciences, Beijing, China; Xiyuan Hospital of China Academy of Chinese Medical Sciences, Scientific and Technological Innovation Project of China Academy of Chinese Medical Sciences
male infertility (asthenozoospermia and oligoasthenozoospermia)
 
 
NCT03989778: Vitamin D and Polycystic Ovarian Syndrome (PCOS)

Recruiting
2
300
RoW
Vitamin D
Aga Khan University
Infertility, Female, Infertility, Vitamin D Deficiency
06/24
06/25
ChiCTR2300071064: Clinical efficacy evaluation of treating kidney-yang asthenospermia with Guilutianjing Capsules based on the theory of "kidney master reproduction"

Not yet recruiting
2
72
 
Therapeutic drugs: turtle deer capsules filled with essence; Administration method: Orally, twice a day, 5 capsules in the morning and evening; Course of treatment: 90 days. ;Therapeutic drugs: Wu Zi Yan Zong Pill; Administration method: Orally, twice a day, 6g in the morning and evening; Course of treatment: 90 days.
Hospital of Chengdu University of Traditional Chinese Medicine; Hospital of Chengdu University of Traditional Chinese Medicine, Science and Technology Development Fund of Hospital of Chengdu University of Traditional Chinese Medicine
Male infertility
 
 
NCT05212337: FITMI - First In Treating Male Infertility

Recruiting
2
282
Europe
Denosumab, Prolia, Sodium chloride, NaCl
Martin Blomberg Jensen
Infertility, Male
12/24
09/25
FertEnhancer, NCT06091969: Supplementation for Male Subfertility

Not yet recruiting
2
64
Canada
Active multi-ingredient supplement (Fertility Enhancer, FE), Inactive placebo (Placebo; PLA)
Hamilton Health Sciences Corporation, One Fertility
Male Infertility
02/25
02/25
NCT05403476: A Trial to Compare Efficacy and Safety of Follitropin Delta Versus Placebo (Inactive Treatment) in the Treatment of Men With Idiopathic Infertility (Unexplained Reduction of Semen Quality) (ADAM)

Recruiting
2
400
Europe, US
FE 999049, REKOVELLE, Follitropin Delta, Placebo
Ferring Pharmaceuticals
Male Idiopathic Infertility
07/26
07/26
METIN, NCT06012682: Clinical Trials Evaluating the Effect of Metformin Treatment on Function Endometrium in Women Diagnosed With Idiopathic Infertility

Not yet recruiting
2
200
NA
Metformin Hydrochloride, Placebo
Medical University of Bialystok, Medical Research Agency, Poland
Infertility, Female
09/27
09/27
NCT03527043: Impact of Escitalopram on Sperm DNA Fragmentation

Recruiting
2
70
US
Escitalopram, Placebo
Weill Medical College of Cornell University
Sperm DNA Fragmentation, Infertility, Male
12/28
02/29
ChiCTR-TRC-10000869: A Phase II, Randomized, Double-Blind, Placebo-Controlled Study to Investigate the Efficacy and Safety of L-O-M MCS-5 in Treating Male Oligoasthenospermia

Completed
1/2
115
 
MCS-5 5mg per day, for 16 weeks ;MCS-5 10mg per day, for 16 weeks ;MCS-5 20mg per day, for 16 weeks ;MCS-5 20mg per day, for 16 weeks
Renji Hospital Affliated to Shanghai Jiaotong University; Health Ever Bio-Tech Co., Ltd(Shanghai), Health Ever Bio-Tech Co., Ltd(Shanghai)
Infertility, Male
 
 
ChiCTR-TRC-11001780: Effect of transcutaneous acupoint electrical stimulation on pregnant outcomes in women undergoing in Embryo Transfer- a multi-center randomized placebo-controlled trial

Completed
1/2
704
 
blank ;mock TEAS ;2 Hz TEAS ;100 Hz TEAS
Neuroscience Research Institute, Peking University; National Natural Science Foundation of China, National Natural Science Foundation of China
infertility
 
 
CS-EOSP-ICSI, NCT04071574: Comparative Study on the Efficacy of Ovarian Stimulation Protocols on the Success Rate of ICSI in Female Infertility

Completed
1/2
200
RoW
Human Chorionic Gonadotropin (hCG), OVITRELLE / PREGNYL, Gonadotropins, MENOPUR, GNRH-A Triptorelin, DECAPEPTYL, GnRH antagonist, CETROTIDE / ORGULATRON
Lebanese University
Female Infertility, Female Infertility Due to Ovulatory Disorder, Premature Ovarian Failure, Polycystic Ovary Syndrome, Female Infertility of Tubal Origin, Ectopic Pregnancy, Salpingitis, Female Infertility Due to Tubal Block, Female Infertility Due to Tubal Occlusion, Hydrosalpinx, Female Infertility - Cervical/Vaginal, Female Infertility Endocrine, Endometriosis, Fibroids, Congenital Uterine Anomaly, Infections Uterine, Female Infertility of Other Origin
08/19
05/23
NCT04268563: Comparing the Effect of Sitagliptin/Metformin and Metformin in PCOS Patients

Recruiting
1/2
80
RoW
placebo, rehydration solution, metformin, Glucophage, Sitagliptin, JANUVIA, Sitagliptin/metformin, JANUMET
Shahid Beheshti University of Medical Sciences
Polycystic Ovary Syndrome, Infertility, ART
07/21
07/21
NCT05103982: Testing a New Self-help Intervention for Infertility Related Distress: a Pilot Study

Recruiting
1/2
20
Canada
Coping with Infertility Program
University of Regina
Infertility, Female
03/22
04/22
NCT05183568: Mindful Self-Compassion (MSC) for Infertility Related Distress

Recruiting
1/2
50
Canada
Mindful Self-Compassion
University of Regina
Infertility, Female, Distress, Emotional, Depressive Symptoms, Anxiety
03/22
05/22
NCT01662466: Effect of Testosterone Treatment on Embryo Quality

Recruiting
1/2
180
US
Testosterone cream (0.5mg per gram), Testosterone, DHEA, Dehydroepiandrosterone, Placebo, Carrier cream without added testosterone
Center for Human Reproduction, Foundation for Reproductive Medicine
Primary Ovarian Insufficiency, Female Infertility Due to Diminished Ovarian Reserve
06/22
12/22
NCT04233892: Clinical Study of in Situ Regeneration of Endometrium

Recruiting
1/2
345
RoW
CBD-bFGF, Collagen/BMMNCs, Estrogen
Yali Hu, Chinese Academy of Sciences
Infertility, Female, of Uterine Origin, Endometrial Fibrosis
12/22
12/24
NCT05279768: Stem Cells and Secretomes for Infertility Therapy in Polycystic Ovary Syndrome (PCOS) Patients With Insulin Resistance.

Recruiting
1/2
40
RoW
UC-MSCs, Secretomes, UC-MSCs and Secretomes, Control
PT. Prodia Stem Cell Indonesia
Polycystic Ovary Syndrome
12/23
12/23
NAPO, NCT06300229: - Novel Approach for Oligospermia

Not yet recruiting
1/2
42
Europe
Denosumab, Prolia, sodium chloride, sodium chloride (NaCl)
Martin Blomberg Jensen
Infertility, Male
12/24
12/25
NCT06379659: Effectiveness of Intrauterine Growth Hormone Administration as an add-on Therapy to Conventional Hormone Therapy Compared to Placebo in Patients With Thin Endometrium Undergoing Frozen Thawed Embryo Transfer

Recruiting
1/2
54
RoW
Growh hormone, Placebo
Isfahan University of Medical Sciences
Thin Endometrium, Infertility Female, Infertility
07/24
11/24

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