Infertility |
ACTRN12612001289808: The use of EmbryoGen in recurrent miscarriage and/or implantation failure patients |
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| Not yet recruiting | 4 | 100 | | | PIVET Medical Centre, PIVET Medical Centre | Infertility, Recurrent miscarriage, Implantation failure | | | | |
ACTRN12616000643471: Comparison of the probability of live birth after elective freezing of all embryos versus standard fresh embryo transfer in patients undergoing in-vitro fertilisation (IVF) |
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| Not yet recruiting | 4 | 400 | | | IVFAustralia Pty L.t.d., IVFAustralia Pty L.t.d., Melbourne IVF, Virtus Health Limited | Subfertility | | | | |
ACTRN12612000740897: A pilot study to assess low dose ovarian stimulation using local anaesthetic to collect oocytes for women having IVF treatment |
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| Recruiting | 4 | 20 | | | Adelaide Fertility Centre Pty Ltd | infertility | | | | |
2008-002689-68: Comparing different ways of preparing patients for frozen-thawed embryo transfer Onderzoek naar verschillende wijzen van voorbereiding op het terugplaatsen van gecryopreserveerde embryo’s. |
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| Ongoing | 4 | 1150 | Europe | progynova, utrogestan, RVG 05311., RVG 11473, Tablet, progynova | Isala Klinieken, location Sophia, MSD | Subfertility in need of IVF and IVF-ICSI treatment., Subfertility in need of IVF and IVF-ICSI treatment., Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
2012-001708-39: Prospective randomized trial concerning three different stimulation methods in IVF/ICSI treatment in poor responders Prospectief gerandomiseerd onderzoek van drie verschillende stimulatiemethodes bij POOR RESPONDERS tijdens een IVF/ICSI behandeling. |
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| Ongoing | 4 | 50 | Europe | Puregon, Injection, Elonva, Puregon | University Hospital Leuven, University Hospital Leuven | Subfertility, Subfertility, Body processes [G] - Reproductive physiologi cal processes [G08] | | | | |
2013-001034-18: Stimulating ovaria in intrauterine insemination: FSH or Clomifene citrate |
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| Ongoing | 4 | 382 | Europe | gonal-f, fostimon, menopur, puregon, clomifeen citraat, Injection, Chewable tablet, Gonal-f Fostimon Menopur Puregon, clomifeen citraat | AMC Amsterdam, ZonMW | Women diagnosed with unexplained subfertility or mild male factor subfertility with an indication for intra uterine insemination, Women diagnosed with unexplained subfertility or mild male factor subfertility with an indication for intra uterine insemination, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR-TRC-12002494: Clinical efficacy of COH with letrozole vs. clomiphene citrate for infertile women after Laparoscopic surgery treatment of minimal to mild endometriosis |
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| Completed | 4 | 210 | | Laparoscopic surgery only ;COH with Letrozole after surgery ;COH with clomiphene citrate after surgery | Reproductive Endocrinology, Department of Obstetrics & Gynecology, West China Second University Hospital; West China Second University Hospital, At our own expense | Endometriosis | | | | |
ChiCTR-TRC-11001820: The Therapeutic Effectiveness of Combination of Laparoscopic Surgery and Medications for Infertile Women with early stage of Endometriosis |
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| Completed | 4 | 156 | | laparoscopic surgery combined with Marvelon ;laparoscopic surgery combined with Marvelon and Dan'e Mixture ;laparoscopic surgery only | West China Second University Hospital of Sichuan University; West China Second University Hospital, Sichuan University, self-raised | Endometriosis | | | | |
2014-000448-13: The exogenous progesterone free luteal phase after GnRHa trigger – a randomized controlled pilot study in high-responder IVF patients |
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| Ongoing | 4 | 100 | Europe | Pregnyl, Lutinus, G03D, Concentrate for solution for injection, Vaginal tablet, Pregnyl, Lutinus | The Fertility Clinic, Skive Regional Hospital, MSD | Infertility, Infertility, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR-TRC-12002246: The effect of FSH administration at the time of triggering ovulation with HCG on the outcome of IVF/ICSI |
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| Completed | 4 | 710 | | give FSH with the dose of 450 IU at the time of triggering ovulation with HCG ;give placebo with dose of 450 IU at the time of triggering ovulation with HCG | Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Science Technology Research Project of Guangdong Province (S2011010004662) | infertility | | | | |
ChiCTR-TRC-14004552: A multicenter, prospective, randomize control study to compare the impact of high purity hMG (HP-HMG) plus recombinant human follicle-stimulating hormone (rFSH) versus mono use of recombinant human follicle-stimulating hormone (rFSH) on HCG day’s progesterone level based on GnRHa long protocol |
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| Completed | 4 | 600 | | high purity hMG (HP-HMG) plus recombinant human follicle-stimulating hormone (rFSH) ;mono use of recombinant human follicle-stimulating hormone (rFSH) | Jiangsu Provincial Hospital; Level of the institution:, Project In Science And Education of Department of Public Health of Jiangsu Province | Infertility | | | | |
2013-003304-39: Assisted reproduction and the early luteal phase The effect of ovulation induction on the endocrine profile Assisteret reproduktion og den tidlige luteal fase Ovulationsinduktionens påvirkning af den endokrine profil |
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| Ongoing | 4 | 179 | Europe | Lentogest, Crinone, Solution for injection, Vaginal gel, Lentogest | Fertilitycenter Odense, Nordic InfuCare, IBSA | Infertility, particularly the luteal phase during IVF, Infertility, particularly the luteal phase during IVF, Body processes [G] - Reproductive physiologi cal processes [G08] | | | | |
ChiCTR-OCH-14004176: Clinical observation of MPA and HMG used for controlled ovarian stimulation in patients with diminshed ovarian reserve |
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| Completed | 4 | 182 | | MPA and HMG ;natural cycle | Shanghai Ninth People's Hospital; Level of the institution:, national natural science foundation | infertility | | | | |
ChiCTR-IPR-14005262: Efficiency of Postoperative Ovulation Induction on Infertile Woman with Minimal-mild Endometriosis |
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| Not yet recruiting | 4 | 130 | | The experimental group was administrated timely ov ;The control group was treated with expectant treat | West China Second Hospital, Sichuan University; West China Second Hospital, Sichuan University, Self-financing | Endometreosis | | | | |
| Recruiting | 4 | 250 | | MPA oral 10mg/d ;MPA+CC | Shanghai Nineth people's hospital; Shanghai Nineth people's hospital, the Natural Science Foundation of Shanghai | infertility | | | | |
ChiCTR-TRC-14004642: Neuromuscular Electrical stimulation (NMES) and biofeedback therapy to improve endometrial growth in Infertile patients with thin endometrium: Prospective randomized controlled study |
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| Recruiting | 4 | 1090 | | NMES ;NMES | Memorial Hospital of Sun Yat-Sen University, IVF Center; Level of the institution:, Science and Technology Planning Project of Guangdong Province, China | thin endometrium | | | | |
| Not yet recruiting | 4 | 230 | | HP-HMG ;HP-HMG | Northwest Women's and Children's Hospital; Northwest Women's and Children's Hospital, Northwest Women's and Children's Hospital ART center | infertility | | | | |
2006-000194-29: In Vitro Maturation (IVM) as part of the treatment of infertility in women with polycystic ovaries (PCO).Is priming with hCG favourable? A prospective randomized study. |
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| Ongoing | 4 | 200 | Europe | Ovitrelle, hCG, Ovitrelle, Ovitrelle | Fertility Clinic, dept. of Obstetrics and gynecology, OUH. | Infertility in women with polycystic ovaries (PCO). | | | | |
2006-001143-59: A prospective, randomised study comparing two fixed daily doses (150 IU versus 225 IU) of recombinant FSH for ovarian stimulation during in-vitro fertilisation treatment in predicted low and intermediate responders based on antral follicle count on 3D ultrasound |
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| Ongoing | 4 | 184 | Europe | Gonal F, Gonal F | School of Human Development | Infertility needing In-Vitro fertilisation treatment | | | | |
2009-012847-40: A Randomised Study Comparing Two Different Regimens of Ovarian Stimulation Using Pergoveris and Cetrorelix for Controlled Ovarian Superovulation in Assisted Conception Treatment. |
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| Ongoing | 4 | 80 | Europe | Pergoveris, Cetrotide, Pergoveris, Cetrotide, Pergoveris, Cetrotide | NHS Lothian, The University of Edinburgh | Subfertility | | | | |
2009-012666-31: The role of progesterone support and genetic polymorphisms for inflammatory cytokines on the risk of developing ovarian hyperstimulation syndrome (OHSS) in women undergoing In-Vitro fertilisation/Intracytoplasmic sperm injection (IVF, IVF−ICSI) treatment for infertility. |
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| Ongoing | 4 | 360 | Europe | Gestone, Cyclogest, Gestone, CYCLOGEST, Gestone, CYCLOGEST | Leeds Teaching Hospitals and University of Leeds | Ovarian Hyperstimulation syndrome | | | | |
ChiCTR-OPC-15005883: Exploration of luteal phase ovarian stimulation in women with poor ovarian response, with optimal pregnancy outcomes in frozen-thawed embryo transfer cycles |
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| Recruiting | 4 | 60 | | luteal phase ovarian stimulation ;luteal phase ovarian stimulation ;luteal phase ovarian stimulation | Linyi People's Hospital Shandong Province; Linyi People's Hospital, no | infertility | | | | |
ChiCTR-IPC-15005870: Clinical study of Fukeyangrong capsules in the treatment of kidney deficiency and blood stasis type of ovarian reserve dysfunction infertility |
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| Not yet recruiting | 4 | 150 | | Fukeyangyan Capsul ;Fukeyangyan Capsul + Hormone replacement therapy ;Hormone replacement therapy | General Hospital of Ningxia Medical University; Level of the institution:, self-financing | The ovarian reserve function decline; Sterility | | | | |
| Not yet recruiting | 4 | 40 | | 60mg,Oral Intake on Demand,3 Months of Treatment ;30mg,Oral Intake on Demand,3 Months of Treatment | China-Japan Friendship Hospital; China-Japan Friendship Hospital, A.Menarini(China)Holding Co,Ltd | Male Infertility;Premature Ejaculation | | | | |
| Not yet recruiting | 4 | 844 | | Oral prednisolone 20 mg/day ;Placebo | Reproductive & Genetic Hospital of CITIC-XIANGYA; Reproductive & Genetic Hospital of CITIC-XIANGYA, Reproductive & Genetic Hospital of CITIC-XIANGYA | infertility | | | | |
ChiCTR-OCH-12002155: Studies on the correlation associated with Follicle-stimulating hormone receptor polymorphism and ovarian response |
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| Recruiting | 4 | 600 | | follicle-stimulating hormone | Central South University; Hunan Provincial Department of Finance, Hunan Provincial Department of Finance | infertility | | | | |
2015-004233-27: Vitamin D Supplementation on Assisted Reproduction Technology (ART) outcomes: arandomized clinical controlled trial and an investigation of the involved biological mechanisms Supplementazione di Vitamina D durante le procedure di Fecondazione in Vitro (IVF): studio controllato randomizzato ed analisi dei meccanismi biologici coinvolti |
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| Ongoing | 4 | 630 | Europe | COLICALCIFEROLO-VITAMINA D3, VITAMINA D, Oral solution, DIBASE - 300.000 UI/ML SOLUZIONE INIETTABILE PER USO ORALE E INTRAMUSCOLARE 2 FIALE 1 ML | FONDAZIONE IRCCS CA' GRANDA OSPEDALE MAGGIORE POLICLINICO, MINISTERO DELLA SALUTE (RF-2013)) | in vitro fertilization infertilità di coppia, al fine di comprendere se la supplementazione di vitamina D (colecalciferolo) nelle donne comporti un aumento in termini di tasso di gravidanza clinica, in vitro fertilization infertilità coniugale trattata con fecondazione in vitro; lo studio vuole verificare se la supplementazione di vitamina D nelle donne possa aumentare i tassi di successo, Body processes [G] - Reproductive physiologi cal processes [G08] | | | | |
ChiCTR-IPR-14005678: A comparison of outcomes from ART cycles stimulated with recombinant follicle stimulating hormone and highly purified human menopausal gonadotropin |
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| Recruiting | 4 | 300 | | rFSH ;Hp-HMG | Maternal & Child Health Care Hospital of Shanxi Province; Maternal & Child Health Care Hospital of Shanxi Province, self-collected | infertility | | | | |
ChiCTR-OIN-16008529: The clinical outcome of MPA and Duphaston and Utrogestan in Primed-progesterone ovarian stimulation protocol for advanced endometriosis patients undergoing IVF cycle |
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| Recruiting | 4 | 450 | | HMG+MPA ;HMG+Duphaston ;HMG+Utrogestan | The Shanghai Ninth People's Hospital affiliated of Shanghai JiaoTong University of medical school; Shanghai Nineth People's Hospital, the Natural Science Foundation of Shanghai | infertility | | | | |
ChiCTR-IPR-15006909: Does DHEA treatment for 12 weeks before in-vitro fertilization improve the live birth rate in poor ovarian responder? |
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| Not yet recruiting | 4 | 710 | | DHEA 3 tablets daily for 12 weeks ;Placebo 3 tablets daily for 12 weeks | Center for Reproductive Medicine, Shandong University; Center for Reproductive Medicine, Shandong University, Nil | Infertility, poor ovarian response | | | | |
| Not yet recruiting | 4 | 1224 | | Embryo cultured and assessed by the GERI time lapse system ;Embryo cultured in the conventional incubator and assessed by the bench-top microscope | Chongqing Health Center for Women and Children; Level of the institution:, Grant from Merck Serono Co., Ltd. | Infertility | | | | |
ChiCTR-IPR-16008329: Comparison of Different Gonadotropins in Non-PCOS Patients with High Ovarian Reserve undergoing in vitro Fertilization: A Randomized Controlled Trial |
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| Recruiting | 4 | 332 | | rFSH as gonadotropin ;HP-HMG as gonadotropin | Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Nil | infertility,High Ovarian Reserve | | | | |
ChiCTR-IPR-17011629: Effect of preconceptional orlistat treatment on in-vitro fertilization outcome in overweight women: a double-blind, placebo randomized clinical trial |
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| Not yet recruiting | 4 | 836 | | Orlistat treatment for 1-3 months ;Placebo treatment for 1-3 months | Center for Reproductive Medicine Affiliated to Shandong University; Center for Reproductive Medicine Affiliated to Shandong University, None | Infertility, obesity | | | | |
2017-004429-34: Changes at the level of the endometrium caused by Lipiodol intrauterine flush. |
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| Not yet recruiting | 4 | 20 | Europe | Lipiodol, Intrauterine solution, Lipiodol | UZ Brussel, UZ Brussel | Female subfertility, Female subfertility, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
2018-000689-13: Pregnancy rate with 1 week versus 2 weeks of hormonal therapy |
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| Not yet recruiting | 4 | 150 | Europe | progynova, utrogestan, RVG 05311., RVG 11473, Tablet, Capsule, progynova, utrogestan | University hospital Brussel, University hospital Brussel | Subfertility in need of IVF and IVF-ICSI treatment, Subfertility in need of IVF and IVF-ICSI treatment, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR-IPR-17012964: The effect of clomiphene citrate on clinical outcome in Progestin-Primed Ovarian Stimulation in women with polycystic ovarian syndrome undergoing IVF cycle |
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| Recruiting | 4 | 320 | | HMG+Duphaston ;HMG+Duphaston+CC | Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine; The Shanghai Ninth People's Hospital, the Natural Science Foundation of Shanghai | infertility | | | | |
ChiCTR-IPR-17012998: The clinical outcomes of MPA and Duphaston and Utrogestan in Primed-progesterone ovarian stimulation protocol for patients with polycystic ovarian syndrome undergoing IVF cycle |
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| Recruiting | 4 | 390 | | HMG+MPA ;HMG+Duphaston ;HMG+Utrogestan | Shanghai Ninth People's Hospital, Shanghai Jiaotong University School of Medicine; None, the Natural Science Foundation of Shanghai | infertility | | | | |
| Not yet recruiting | 4 | 650 | | PGS ;ICSI | International Peace Maternity & Child Health Hospital; International Peace Maternity & Child Health Hospital, Shanghai shen-kang hospital development center | Male factor infertility | | | | |
ChiCTR-IPR-17014076: The effect of Letrozole on clinical outcome in Progestin-Primed Ovarian Stimulation in women with polycystic ovarian syndrome undergoing IVF cycle |
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| Recruiting | 4 | 300 | | Follicular stage HMG combined with progestin ;HMG + progestin + letrozole | Shanghai Ninth People’s Hospital, Shanghai Jiaotong University School of Medicine; None, the Natural Science Foundation of China | infertility | | | | |
ChiCTR1800018250: Clinlical effect of emergency ovum pick-up in the IVF/ICSI cycles with pre-ovulatory serum E2 decrease: a randomized controlled trial |
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| Recruiting | 4 | 70 | | Emergency OPU ;Scheduled OPU | Shanghai East Hospital, Tongji University School of Medicine; Shanghai East Hospital, Tongji University School of Medicine, Shanghai Natural Science Foundation | Infertility | | | | |
2018-002000-13: Effect of recombinant FSH dosing following corifollitropin alfa in patients undergoing IVF/ICSI in a GnRH antagonist protocol: a randomized controlled dose-finding study. |
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| Not yet recruiting | 4 | 261 | Europe | Elonva, Puregon, EU/1/09/609/002, Solution for injection, Elonva, Puregon | University hospital Brussel, MSD Belgium | Subfertility in need of IVF and IVF-ICSI treatment, Subfertility in need of IVF and IVF-ICSI treatment, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR1800014346: The effect of metformin on improving the fecundity of minimal/mild endometriosis-associated infertility patient: A prospective, randomized controlled trial |
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| Not yet recruiting | 4 | 200 | | metformin ;Observation | West China Second University Hospital, Sichuan University; West China Second University Hospital, Sichuan University, National key research and development program | endometriosis | | | | |
ChiCTR1800014347: Metformin Improves the fecundity of PCOS Infertile Patients with Insulin Resistance: A Randomized Controlled Trial |
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| Not yet recruiting | 4 | 200 | | metformin ;Observation | West China Second University Hospital, Sichuan University; West China Second University Hospital, Sichuan University, self-fund | Polycystic ovarian syndrome | | | | |
ChiCTR1800018434: Cancelled by the investigator Effect of intraoperative intravenous ketamine on depression in infertility and pregnancy loss patients |
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| Suspended | 4 | 130 | | 10ml intravenous injection of 0.5mg/kg ketamine when anesthesia induction ;10ml intravenous injection of 0.9% saline when anesthesia induction | Shenzhen Maternity and Child Healthcare Hospital; Shenzhen Maternity and Child Healthcare Hospital, Self-funding | Depression | | | | |
ChiCTR-IPR-17010584: Clinical Study of Kuntai Capsule on Follicular Development of Diminished Ovarian Reserve Patients With Infertility |
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| Not yet recruiting | 4 | 58 | | Heyan Kuntai capsule ;DHEA | West China Second Hospital; Sichuan University; West China Second Hospital; Sichuan University, Shanghai Haitian Pharmaceutical Technology Development Co Ltd | decline in ovarian reserve | | | | |
ChiCTR1800014348: Metformin Improves the fecundity of PCOS Infertile Patients with Insulin Resistance in IVF-ET: A Randomized Controlled Trial |
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| Not yet recruiting | 4 | 200 | | Metformin ;Observation | West China Second University Hospital, Sichuan University; West China Second University Hospital, Sichuan University, self-fund | Polycystic ovarian syndrome | | | | |
2018-000105-23: Support of the implantation of the embryo after transferring to the uterus in IVF/ICSI: a comparison between taking progesterone by mouth or vaginal. |
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| Not yet recruiting | 4 | 30 | Europe | Film-coated tablet, Vaginal capsule, soft, Duphaston 10, filmomhulde tabletten 10 mg, Utrogestan | UZ Brussel, UZ Brussel | Female infertility, Female inability to conceive a child, Body processes [G] - Reproductive physiologi cal processes [G08] | | | | |
ACTRN12616001539426: Effect of ovarian stimulation on oocyte quality and embryonic aneuploidy: a prospective, randomised controlled trial |
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| Completed | 4 | 240 | | | University New South Wales - Medicine, Ferring Pharmaceuticals | Subfertility | | | | |
ChiCTR-IIR-17011033: A multicenter, prospective, randomize control study to compare the impact of Letrozole plus Urofollitropin versus mono use of Urofollitropin on live birth rate after intrauterine insemination (IUI) |
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| Recruiting | 4 | 12502 | | Letrozole plus Urofollitropin ;Urofollitropin | Jiangsu Provincial Hospital; Jiangsu Provincial Hospital, Jiangsu Qiang Wei project (zx201110) | Infertility | | | | |
2018-003556-20: How do different ovarian stimulation protocols affect endometrial receptivity during a fresh in vitro fertilization attempt? Avaliação do efeito de diferentes protocolos de estimulação ovárica na recetividade endometrial após um tratamento de fertilização in vitro |
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| Not yet recruiting | 4 | 24 | Europe | Injection, Elonva, Puregon | INSTITUTO VALENCIANO DE INFERTILIDADE - CLÍNICA DE REPRODUÇÃO ASSISTIDA, LDA, Organon Portugal, Sociedade Unipessoal, Lda | Women with a clinical indication to undergo Assisted Reproductive Technologies for infertility with a predicted normal response to Ovarian Stimulation and planned for a single blastocyst transfer, Women with a clinical indication to undergo Assisted Reproductive Technologies for infertility with a predicted normal response to Ovarian Stimulation and planned for a single blastocyst transfer, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
| Not yet recruiting | 4 | 46 | Europe | Elonva, Puregon, Solution for injection, Elonva, Puregon | UZ Brussel, MSD | infertility, infertility, Analytical, Diagnostic and Therapeutic Techniques and Equipment [E] - Surgical Procedures, Operative [E04] | | | | |
2018-004153-24: What is the best moment for performing an HSG in women with a unfulfilled childwish? Wat is het beste moment voor het verrichten van een HSG bij vrouwen met een onvervulde kinderwens? |
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| Ongoing | 4 | 554 | Europe | Lipiodol Ultrafluid, Injection, Lipiodol | Amsterdam UMC - location Vrije Universiteit Amsterdam, Amsterdam UMC - location Vrije Universiteit Amsterdam | The research population consists of infertile women aged between 18 and 39 years of age, who have a spontaneous menstrual cycle and with a perceived low risk for tubal pathology, undergoing fertility work-up, Women with an unfulfilled childwish between 18 and 39 years of age, who have a spontaneous menstrual cycle and at low risk for tubal pathology, undergoing fertility work-up., Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR-IPR-17012194: Effect of rhGH and DHEA adjuvant therapy on poor ovarian response and elderly patients undergoing IVF-ET |
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| Recruiting | 4 | 100 | | rhGH+DHEA ;rhGH | The First Affiliated Hospital of Anhui Medical University; The First Affiliated Hospital of Anhui Medical University, Self-financing | infertility | | | | |
2018-004192-12: Oil- based versus water-based contrast media for hysterosalpingography (HSG) in women with an unfulfilled childwish with ovulation disorders, at high risk for tubal pathology or above 38 years of age. |
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| Ongoing | 4 | 930 | Europe | Lipiodol Ultrafluid, Visipaque, Injection, Lipiodol UltraFluid, Visipaque | Amsterdam UMC, location VU medical Center, Amsterdam UMC - location Vrije Universiteit Amsterdam | The research population consists of infertile couples who have tried to conceive for at least 12 months, or have oligo- or anovulation. We will focus on women with ovulation disorders, or at high risk for tubal pathology or above 38 years of age., The research population consists of infertile couples who have tried to conceive for at least 12 months or have an irregular menstrual cycle or at high risk for tubal pathology or >38 years of age., Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
2019-001539-29: The effect of adding extra rectally progesterone when the serum progesterone level is too low during infertility treatment with thawed embryos. Effekten af at tilføre ekstra progesteron via endetarmen til kvinder med lavt progesteron niveau under fertilitetsbehandling med optøede æg. |
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| Ongoing | 4 | | Europe | Cyclogest, Vaginal capsule, Cyclogest | The Fertility Clinic, Skive Regional Hospital, The Fertility Clinic, Skive Regional Hospital | Infertility, Infertility Barnløshed, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
2019-003468-27: A study investigating whether progesterone supplementation in otherwise unmedicated, natural menstrual cycles can improve live birth rates |
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| Not yet recruiting | 4 | 200 | Europe | Cyclogest, Pessary, Cyclogest | Homerton University Hospital NHS Trust, LD Collins & Co. Ltd, SPD Development Company Limited | Unexplained infertility, Couples having difficulty conceiving despite normal test results, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
2018-003484-56: Corifolitropin alfa for double ovarian stimulation in low responders Corifolitropina alfa para doble estimulación en bajas respondedoras |
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| Not yet recruiting | 4 | 292 | Europe | Solution for injection, ELONVA 150 microgramos solución inyectable | Miguel Caballero Campo, None | Infertility in patients requiring in vitro fertilization treatment with poor ovarian response profile, defined by Bologna Criteria. Infertilidad en pacientes tributarias de tratamiento con fecundación in vitro y con perfil de baja respuesta a la estimulación definido según Criterios de Bolonia., Low ovarian reserve in infertile patients Baja reserva funcional ovárica asociada a infertilidad, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR-IPR-16010209: Application of Growth Hormone in Patients with Non-ovarian Hyporesponsiveness and Poor Embryonic Development |
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| Not yet recruiting | 4 | 252 | | Growth hormone ;No | Assisted Reproduction Center, Northwest Women and Children's Hospital; Northwest Women and Children's Hospital, Special Fund for Clinical Medical Research of Chinese Medical Association | Infertility Disease | | | | |
ChiCTR-IPR-17010906: The effects of preventing premature LH surge in ovarian poor responders using GnRH antagonist and MPA: a RCT |
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| Recruiting | 4 | 340 | | GnRH antagonist ;MPA | Shanghai Ninth People's Hospital affiliated Shanghai Jiaotong University School of Medicine; Shanghai Ninth People's Hospital affiliated Shanghai Jiaotong University School of Medicine, National Nature Science Foundation of China | infertility | | | | |
ChiCTR1800015958: The effect of oral progesterone capsule for luteal phase support on pregnancy rate: a randomized controlled trial |
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| Recruiting | 4 | 1311 | | oral progesterone capsule 200mg bid for luteal phase support ;Oral progesterone capsule 200mg tid for luteal phase support ;Vaginal Crinone gel 90mg/d for luteal phase support | The Reproductive Medical Center, Shandong University; The Center of Reproductive Medicine, Shandong University, Zhejiang Xianju Pharmaceutical Co., Ltd. | Infertility | | | | |
ChiCTR1800019730: Effect of three day antagonist pretreatment before superovulation initiation on outcome of in vitro fertilization-embryo transfer treatment with antagonist protocol: a randomized controlled trial |
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| Recruiting | 4 | 136 | | GnRH-ant pretreatment was used on the 2nd to 4th day of menstruation ;No GnRH-ant pretreatment was used on the 2nd to 4th day of menstruation | The People's Hospital of Guangxi Zhuang Autonomous Region; the People's Hospital of Guangxi Zhuang Autonomous Region, Hospital youth fund | infertility | | | | |
ChiCTR1900027963: Study for Yimaxin for luteal phase support in assisted reproduction |
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| Not yet recruiting | 4 | 100 | | A1 Dydrogesterone10mg/bid +A2 Yimaxin100mg/bid +A3 Yimaxin100mg/tid ;B1 crinone90mg/qd + B2 Yimaxin100mg/tid + B3 Yimaxin200mg/bid | Ningxia Medical Genral Hospital; Ningxia Medical Genral Hospital, Self | Fmale infertility | | | | |
ChiCTR1900022631: Addition of luteal estradiol supplementation in GnRH antagonist IVF/ICSI cycles: a randomized controlled study |
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| Recruiting | 4 | 472 | | 17β-estradiol supplementation vaginally +Crinone supplementation vaginally+ Duphaston p.o. ;Crinone supplementation vaginally+ Duphaston p.o. | Women’s Hospital, Zhejiang University School of Medicine; Women’s Hospital, Zhejiang University School of Medicine, National Key R&D Program of China (2018YFC1004900) | female infertility | | | | |
2020-000201-84: Iron deficiency in fertility treatment Eisenmangel in der Kinderwunschbehandlung |
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| Not yet recruiting | 4 | 48 | Europe | Ferinject, Ferretab, 13811-051-30, Solution for infusion, Capsule, hard, Ferinject, Ferretab | Das Kinderwunsch Institut Schenk GmbH, Das Kinderwunsch Institut Schenk GmbH | infertility Unfruchtbarkeit, infertility Unfruchtbarkeit, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
2019-002040-24: Iron defiency as an ignored cause of infertility Rautavaje hedelmättömyyden osatekijänä |
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| Not yet recruiting | 4 | 62 | Europe | Ferinject, Infusion, Ferinject | Dextra fertility clinic, Annika Tulenheimo-Silfvast, Dextra fertility clinic, Dextra Fdertility Clinic, Vifor AG | Infertility Lapsettomuus potilailla , joilla rautavaje, Infertility Lapsettomuus potilailla , joilla rautavaje, Diseases [C] - Hormonal diseases [C19] | | | | |
ChiCTR1900022333: Effects of Atosiban on clinical outcomes of in vitro fertilization-embryo transfer |
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| Not yet recruiting | 4 | 1100 | | atosiban versus placebo | Northwest Women's and Children's Hospital; Northwest Women's and Children's Hospital, Northwest Women's and Children's Hospital | infertility | | | | |
ChiCTR1800020269: Research for the treatment of infertility with traditional Chinese medicine |
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| Recruiting | 4 | 225 | | Zi Gui Nv Zhen capsule ;Zi Gui Nv Zhen capsule | Beijing Obstetrics and Gynecology Hospital, Capital Medical University; Beijing Obstetrics and Gynecology Hospital, Capital Medical University, Association for maternal and child health studies | Infertility | | | | |
2020-001218-39: Estradiol levels in early pregnancy after natural, estradiol + progesterone or gonadotrophin stimulated frozen embryo transfer (FET) cycle Østradiol-niveauer i tidlig graviditet efter naturlig, østradiol + progesteron eller gonadotropin-stimuleret frysecyklus. |
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| Not yet recruiting | 4 | 300 | Europe | estradiol, bemfola, cyclogest, ovitrelle, 30158EU/1/00/165/007( marketing code), Tablet, Solution for injection/infusion, Vaginal tablet, Suspension for injection in pre-filled pen, Estradiol, bemfola, Cyclogest, ovitrelle | fertility clinic, Herlev university hospital, Fertilti clinic Hvidovre University hospital, Fertility clinic Herlev University Hospital, Fertility clinic Hvidovre University Hospital | Infertile women Infertile kvinder, Infertile women Ufrivilligt barnløse kvinder, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR2000029169: The effect of Letrozole on clinical outcome in Progestin-Primed Ovarian Stimulation in women in normalovulatory women undergoing IVF cycle |
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| Recruiting | 4 | 300 | | A组 ;B组 | Shanghai Ninth People's Hospital; Shanghai Ninth People's Hospital, the Natural Science Foundation of China | infertility | | | | |
ChiCTR-INR-17010809: A multicenter, randomized, controlled clinical trial of the traditional Chinese medicine of Tonifying the kidney (Zishen yutai pills) in the assisted reproductive frozen thawed embryo transfer |
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| Recruiting | 4 | 880 | | taking Zishen Yutai Pill ;taking placebo | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University; Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Guangzhou Science Technology and Innovation Commission | Infertility | | | | |
ChiCTR-IPR-17010630: The application of Zishen Yutai Pill in aged women undergoing in vitro fertilization-embryo transfer: a multi-center double-blind randomized controlled trial |
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| Not yet recruiting | 4 | 1466 | | taking Zishen Yutai Pill ;taking placebo | Sun Yat-sen Memorial Hospital, Sun Yat-sen University; Sun Yat-sen Memorial Hospital, Sun Yat-sen University, Nil | infertility | | | | |
2020-005552-38: Vaginal progesterone as luteal support for improvement of live birth in frozen/thawed in-vitro fertilization natural cycles; a multicenter, open, randomized trial |
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| Not yet recruiting | 4 | 1800 | Europe | Lutinus, Vaginal tablet, Lutinus | Västragötalandsregionen, Sahlgrenska Universitetssjukhuset, ALF medel | infertility, infertility, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR2000029341: A prospective randomized controlled study on the effect of growth hormone (GH) combined with metformin (Met) in improving the reproductive outcome of assisted pregnancy in infertile patients with low ovarian reserve function |
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| Not yet recruiting | 4 | 442 | | GH combined with Metformin, COS ;COS | West China Second University Hospital, Sichuan University; West China Second University Hospital, Sichuan University, Clinical research fund of West China Second University Hospital Sichuan University | Infertility, DOR | | | | |
2020-004491-17: Oral versus vaginal progesterone for luteal phase support in frozen embryo transfer cycles. |
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| Not yet recruiting | 4 | 150 | Europe | Tablet, Capsule, soft, Duphaston 10 mg, Utrogestan Vaginal 200 mg | UZ Brussel, Abbott | progesterone as luteal phase supplementation in frozen embryo transfer cycles, frozen embryo transfer cycles for infertility treatment, Body processes [G] - Reproductive physiologi cal processes [G08] | | | | |
2020-002135-30: A study concerning the influence of tubal flushing with oil on pregnancy and live birth in women with fertility problems. |
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| Not yet recruiting | 4 | 736 | Europe | Solution for injection, Lipiodol® Ultra Fluide | Antwerp University Hospital (UZA), Beglian Health Care Knowledge Center (KCE | Infertility defined as lack of conception despite 12 months of unprotected intercourse, or three cycles of donor insemination without pregnancy or three ovulatory ovulation induction cycles without pregnancy, Infertility, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
NCT03169166: The Use of GnRH Agonist Trigger for Final Follicle Maturation in Women Undergoing Assisted Reproductive Technologies |
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| Completed | 4 | 277 | RoW | Triptorelin, Gonapeptyl | American University of Beirut Medical Center | Sterility, Infertility | 07/21 | 10/21 | | |
2021-000941-42: INTEnsity of ovariaN Stimulation and Embryo Quality Intensidad de la estimulación ovárica y calidad embrionaria |
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| Ongoing | 4 | 100 | Europe | Solution for injection in pre-filled pen, Solution for injection, Capsule, soft, , Ovaleap 900 UI/1,5 ml solucion inyectable, Ovaleap 450 UI/0,75 ml solucion inyectable, Ovaleap 300 UI/0,5 ml solucion inyectable, Orgalutran 0,25 mg/0,5 ml solución inyectable, Ovitrelle 250 microgramos solución inyectable en pluma precargada., Decapeptyl diario 0,1 mg polvo y disolvente para solución inyectable, utrogestan 200 mg cápsulas blandas, Omifin 50 mg comprimidos | Fundacion Santiago Dexeus Font, Fundación Santiago Dexeus Font | To compare the number of GQB and the morphokinetic parameters of early embryo development in infertile suboptimal patients undergoing two different intensities of ovarian stimulation, a milder approach ( Clomiphene Citrate (CC) 50mg/day plus 150IU daily dose of rFSH) and a more intense approach (300IU daily dose of rFSH). Comparar el número de embriones buena calidad y los parámetros morfocinéticos de desarrollo temprano de embriones en pacientes infértiles subóptimas sometidas a dos intensidades de estimulación ovárica diferentes, una más suave (Citrato de Clomifeno más 150 UI FSHr diariamente) y una mas intensa (300 UI FSHr diariamente), To compare the two stimulation groups of Clomiphene Citrate (CC) 50mg/day plus rFSH 150IU vs. 300IU regarding the number of good quality blastocysts (GQB) in suboptimal patients. Comparar los dos grupos de estimulación de Citrato de Clomifeno más 150 UI FSHr vs. 300UI FSHr en cuanto al número de blastocistos de buena calidad en pacientes subóptimas, Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
NCT03619707: Oral Versus Vaginal Progesterone in the Luteal Support in Cryo-warmed Embryo Transfer Cycles |
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| Completed | 4 | 157 | RoW | Progesterone | American University of Beirut Medical Center | Sterility, Infertility | 08/21 | 10/21 | | |
2020-002453-26: Eight weeks of pre-treatment with hCG before in vitro fertilization in women with low ovarian reserve. |
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| Not yet recruiting | 4 | 20 | Europe | Solution for injection in pre-filled syringe, Ovitrelle | Rigshospitalet, Gedeon Richter | Female Infertility, Infertility is a term doctors use if a woman hasn't been able to get pregnant after at least one year of trying., Diseases [C] - Female diseases of the urinary and reproductive systems and pregancy complications [C13] | | | | |
ChiCTR1900025084: A randomized, controlled, and multicentric clinical study for the quality, safety and fertility promotion of hysterosalpingography in infertile women by X-ray and contrast-enhanced ultrasonography |
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| Not yet recruiting | 4 | 400 | | Ultrasonic imaging ;X-ray imaging | Army Specialty Medical Center; Army Specialty Medical Center, self-raised | infertility | | | | |
NCT04727671: Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes in Polycystic Ovary Syndrome Patients. |
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| Completed | 4 | 50 | RoW | Triptorelin acetate, Cetrorelix, recombinant-FSH or recombinant-FSH + human Menopausal Gonadotropin, Human Chorionic Gonadotropin (hCG) | Damascus University | In Vitro Fertilization, Intracytoplasmic Sperm Injection, Infertility, Polycystic Ovary Syndrome | 08/21 | 12/21 | | |
ChiCTR1800018246: GnRH antagonist and progestin used for preventing premature ovulation in infertile women during IVF/ICSI treatment: a prospective randomized controlled trial |
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| Recruiting | 4 | 348 | | PPOS protocol ;GnRH-A protocol | Shanghai East Hospital, Tongji University School of Medicine; Shanghai East Hospital, Tongji University School of Medicine, Shanghai Natural Science Foundation | Infertility | | | | |
ChiCTR1800017931: Effect of Luteal estrogen pre-treatment in sub-optimal responders in GnRH antagonist protocol: a prospective randomized trial |
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| Recruiting | 4 | 370 | | Luteal estrogen pre-treatment ;no pre-treatment | Shenzhen Zhongshan Urology Hospital; Shenzhen Zhongshan Urology Hospital, Clinical research fund of Shenzhen Zhongshan Urology Hospital | Female infertility | | | | |
2021-001835-22: A randomized comparison of one controlled ovarian stimulation with corifollitropin alfa (CFA) versus up to three modified natural cycles (MNC) in expected and established poor responders |
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| Not yet recruiting | 4 | 300 | Europe | Solution for injection, Solution for injection in pre-filled syringe, ELONVA, Puregon, Ovitrelle, Orgalutran | Ghent University Hospital, N.V. Organon | this study will compare the efficacy of two different strategies for the management of predicted low prognosis patients under stimulation for IVF/ICSI: up to three MNCs (Modified Natural Cycle) (control group) versus a single GnRH antagonist CFA (corifollitropin alfa) (intervention group).The study population is aimed at women with a clinical indication for Assisted Reproductive Technology (ART) with an expected low response to ovarian stimulation., Subfertility, Body processes [G] - Reproductive physiologi cal processes [G08] | | | | |
NCT03701750: Effect of LMWH on Pregnancy Outcome in Women With Multiple Failures of IVF-ET |
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| Recruiting | 4 | 240 | RoW | Low Molecular Weight Heparin (enoxaparin sodium) | Shenzhen Zhongshan Urology Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Renmin Hospital of Wuhan University | Infertility | 10/21 | 10/22 | | |
ChiCTR1800019565: The effects of Tadalafil on the clinical outcome in women undergoing frozen embryo transfer: a randomized controlled trial |
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| Recruiting | 4 | 172 | | Tadalafil supplementation in cycle regimens to prepare the womb lining for ovulation induction cycle FET ;ovulation induction cycle FET | Shanghai Orient Hospital, Tongji University School of Medicine; Shanghai Orient Hospital, Tongji University School of Medicine, Shanghai Natural Science Foundation | Infertility | | | | |
ChiCTR1900027338: To compare effect of two protocol in hormone-replacement cycle for frozen-thawed embryo transfer: a single center, randomized, prospective, open-label study |
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| Not yet recruiting | 4 | 800 | | 90 mg progesterone vaginal gel plus 10mg dydrogesterone BID (20mg) ;90 mg progesterone vaginal gel plus 20mg dydrogesterone BID (40mg) | The First Affiliated Hospital of Sun Yat-sen University; The First Affiliated Hospital of Sun Yat-sen University, China health promotion foundation | infertility | | | | |
ChiCTR2000040464: the role of LMWH on regulating uterine immune microenviroment and its application in patients |
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| Recruiting | 4 | 200 | | low molecular weight heparin | Ruijin Hospital affilited to Medical school of Shanghai Jiaotong University; Ruijin Hospital affilited to Medical school of Shanghai Jiaotong University, Horizontal project funding | infertility | | | | |
NCT04510870: Iron Deficiency as an Ignored Cause of Infertility |
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| Not yet recruiting | 4 | 62 | Europe | Ferric Carboxymaltose Injection, Ferinject, NaCl infusion | Dextra Fertility Clinic | Iron Deficiency, Infertility | 12/21 | 02/22 | | |
ChiCTR2100041849: Study on the effect of hysterosalpingography with opium poppy lipiodol on infertility patients |
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| Recruiting | 4 | 468 | | Hysterosalpingography with poppy lipiodol ;Hysterosalpingography with ioverol | The Second Hospital of Hebei Medical University; The Second Hospital of Hebei Medical University, China Health Promotion Foundation | Infertility | | | | |
ChiCTR2100045253: A single-center randomized controlled safety and efficacy research of tadalafil in the treatment of infertile patients with ED |
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| Recruiting | 4 | 72 | | Tadalafil ;Placebo | Shanghai General Hospital; Shanghai General Hospital, Qilu Pharmaceutical (Hainan) Co., Ltd. | Male infertility | | | | |
NCT04724343: Effect of GnRH Agonist vs GnRH Antagonist on IVF/ICSI Outcomes. |
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| Completed | 4 | 50 | RoW | Triptorelin acetate, Cetrorelix, recombinant-FSH or recombinant-FSH + human Menopausal Gonadotropin, Human Chorionic Gonadotropin (hCG) | Damascus University | In Vitro Fertilization, Intracytoplasmic Sperm Injection, Infertility | 01/22 | 07/22 | | |
| Recruiting | 4 | 165 | Europe | Desogestrel 0.075 MG, Orgalutran | Casa di Cura Privata Villa Mafalda | IVF, Infertility | 01/22 | 02/22 | | |
PPOS, NCT04654741: The Rate of Embryo Euploidy in Progestin-primed Ovarian Stimulation Cycles |
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| Recruiting | 4 | 396 | Europe | Medroxyprogesterone Acetate, Farlutal, Ganirelix Acetate, Orgalutran | Casa di Cura Privata Villa Mafalda | IVF, Infertility | 02/22 | 12/22 | | |
NCT04727684: Effect of GnRH Agonist vs GnRH Antagonist on Oocyte Morphology in Polycystic Ovary Syndrome Patients During IVF/ICSI |
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| Completed | 4 | 50 | RoW | Triptorelin acetate, Cetrorelix, recombinant-FSH or recombinant-FSH + human Menopausal Gonadotropin, Human Chorionic Gonadotropin (hCG) | Damascus University | In Vitro Fertilization, Infertility, Intracytoplasmic Sperm Injection, Polycystic Ovary Syndrome | 02/22 | 05/22 | | |
ChiCTR2100043606: The effect of recombinant Luteinizing Hormone (LH) supplementation in controlled ovarian hyperstimulation outcome in women with low LH concentration during mid- and late-follicular phase: a single-center, prospective, randomized controlled study |
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| Recruiting | 4 | 110 | | rFSH ;rFSH+rLH | West China Second Hospital, Sichuan University; West China Second Hospital, Sichuan University, China health promotion fund for research in reproductive sciences, 20H08189 | Infertility | | | | |
NCT04724486: Effect of GnRH Agonist vs GnRH Antagonist on Oocyte Morphology During IVF/ICSI |
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| Completed | 4 | 50 | RoW | Triptorelin acetate, Cetrorelix, recombinant-FSH or recombinant-FSH + human Menopausal Gonadotropin, Human Chorionic Gonadotropin (hCG) | Damascus University | In Vitro Fertilization, Intracytoplasmic Sperm Injection, Infertility | 03/22 | 07/22 | | |
ChiCTR2000031788: The Efficacy of Dydrogesterone on Pregnancy Outcomes After Surgery for Endometriosis-Associated Infertility: a Multicentre Prospective Randomized Controlled Trial |
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| Not yet recruiting | 4 | 504 | | dydrogesterone ;GnRH-a ;dydrogesterone ;GnRH-a | Guangzhou Women and Children’s Medical Center; Guangzhou Women and Children's Medical Center, Bethune Charitable Foundation | endometriosis | | | | |
PE-PMA, NCT04695483: Reduction of Progesterone Elevation at Trigger in POR After Long Acting COS Compared With Daily COS: a Prospective Randomized Trial |
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| Completed | 4 | 110 | Europe | Corifollitropin alfa, Follitropin Beta | IRCCS San Raffaele | Infertility | 01/24 | 05/24 | | |
ChiCTR1900024192: Endometrial preparation for frozen embryo transfer: a randomized controlled trial comparing modified natural regimen versus hormone therapy regimen |
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| Recruiting | 4 | 800 | | hCG 10000U for ovulation ;Progynova | Shenzhen Maternity and Child Healthcare Hospital; Shenzhen Maternity and Child Healthcare Hospital, No funding | Infertility | | | | |