| cyclosporine / Generic mfg. |
NCT00006055: Autologous Peripheral Blood Stem Cell Transplantation in Patients With Life Threatening Autoimmune Diseases |
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| Unknown status | N/A | 10 | US | anti-thymocyte globulin, cyclophosphamide, cyclosporine, filgrastim, methylprednisolone, prednisone, Autologous Peripheral Blood Stem Cell Transplantation | Fairview University Medical Center | Purpura, Schoenlein-Henoch, Graft Versus Host Disease, Anemia, Hemolytic, Autoimmune, Rheumatoid Arthritis, Churg-Strauss Syndrome, Hypersensitivity Vasculitis, Wegener's Granulomatosis, Systemic Lupus Erythematosus, Giant Cell Arteritis, Pure Red Cell Aplasia, Juvenile Rheumatoid Arthritis, Polyarteritis Nodosa, Autoimmune Thrombocytopenic Purpura, Takayasu Arteritis | | | | |
NCT00017654: Study of Allogeneic Bone Marrow and T-Cell Depleted, CD34+ Peripheral Blood Stem Cell Transplantation in Patients With Aplastic Anemia |
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| Unknown status | N/A | 3 | US | anti-thymocyte globulin, cyclophosphamide, cyclosporine, methylprednisolone, Allogeneic Bone Marrow Transplantation | Northwestern Memorial Hospital | Graft Versus Host Disease, Aplastic Anemia | | | | |
NCT00290628: Donor Umbilical Cord Blood Transplant in Treating Patients With Hematologic Cancer |
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| Terminated | N/A | 43 | US | anti-thymocyte globulin, busulfan, cyclophosphamide, cyclosporine, filgrastim, melphalan, methylprednisolone, mycophenolate mofetil, radiation therapy, umbilical cord blood transplantation | Masonic Cancer Center, University of Minnesota, National Cancer Institute (NCI) | Chronic Myeloproliferative Disorders, Diamond-blackfan Anemia, Fanconi Anemia, Graft Versus Host Disease, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm, Myelodysplastic Syndromes, Myelodysplastic/Myeloproliferative Diseases | 04/07 | 04/07 | | |
NCT02028416: Comparison of Two Different Doses of Rabbit ATG-Fresenius With Cyclosporin in the Treatment of Acquired Aplastic Anaemia |
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| Unknown status | N/A | 60 | RoW | ATG-fresenius, Rabbit ATG, ATG-F | National Institute of Blood Disease Center, Pakistan | Aplastic Anemia | 12/17 | 12/17 | | |
ChiCTR-IOR-17011653: A prospective, randomized, controlled clinical study of non transfusion dependent non severe aplastic anemia treated with cyclosporine, androgen and levamisole hydrochloride |
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| Not yet recruiting | N/A | 248 | | none ;levamisole hydrochloride | The First affiliated Hospital of Zhejiang Chinese Medical University; The First affiliated Hospital of Zhejiang Chinese Medical University, raise independently | Aplastic anemia | | | | |
NCT03218657: Clinical Study of Non Severe Aplastic Anemia Treated With Cyclosporine, Androgen and Levamisole |
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| Unknown status | N/A | 248 | RoW | levamisole hydrochloride, levamisole, Androgens, Cyclosporins | Shengyun Lin | Aplastic Anemia | 07/19 | 07/22 | | |
ChiCTR1900023476: Multicenter, prospective and open clinical study for rapamycin in the treatment of autoimmune hemolytic anemia |
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| Not yet recruiting | N/A | 80 | | glucocorticoid ;glucocorticoid ＆ Ciclosporin ;glucocorticoid ＆ rapamycin ;rapamycin | Tianjin Medical University General Hospital; Tianjin Medical University General Hospital, Clinical Founding | Autoimmune | | | | |
ChiCTR-IOR-16008738: A single center, randomized, controlled, opened label study for evaluating Cyclosporin alone or combined with Stanozolol in the treatment of aplastic anemia |
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| Recruiting | N/A | 200 | | Cyclosporin ;Cyclosporin and Stanozolol | The First Affiliated Hospital of Zhengzhou University; The First Affiliated Hospital of Zhengzhou University, The First Affiliated Hospital of Zhengzhou University Dr.Scientific Research Foundation | aplastic anemia | | | | |
ChiCTR1800019487: A clinical study for different infusion methods of mesenchymal stem cells in the treatment of aplastic anemia |
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| Recruiting | N/A | 60 | | Treatment regimen of ATG combined with cyclosporin immunosuppression ;MSCs+Treatment regimen of ATG combined with cyclosporin immunosuppression | Jiangmen Central Hospital; Jiangmen Central Hospital, Wu Jieping medical association foundation | Aplastic anemia | | | | |
ChiCTR2000038744: To explore the intervention effect of Xiaoyu Xiezhuo Yin on chronic cyclosporin nephropathy in patients with aplastic anemia based on autophagy and ACE2-Ang(1-7)-Mas axis |
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| Not yet recruiting | N/A | 60 | | none ;none ;Conventional treatment ;Conventional treatment+traditional Chinese medicine | The First Affiliated Hospital of ZheJiang Chinese Medical University; The First Affiliated Hospital of ZheJiang Chinese Medical University, Self-funded | Chronic cyclosporine nephropathy | | | | |
ChiCTR1900027553: Clinical therapies for patients in subtypes of non-severe aplastic anemia |
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| Not yet recruiting | N/A | 490 | | Cyclosporine ;Cyclosporine ;Cyclosporine+Danazol ;CSA+TPO+G-CSF | Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences; Institute of Hematology & Hospital of Blood Diseases, Chinese Academy of Medical Sciences, Tianjin Major Disease Prevention and Control Science and Technology Project | non-severe aplastic anemia | | | | |
NCT05571332: Efficacy and Safety of Avatrombopag Combined With IST for the Treatment of HAAA and SAA With Abnormal Liver Function |
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| Recruiting | N/A | 39 | RoW | Avatrombopag 20 MG Oral Tablet, porcine ATG, Cyclosporine(CsA) | Institute of Hematology & Blood Diseases Hospital | Aplastic Anemia | 12/23 | 06/24 | | |
NCT02845596: Unrelated Donor Transplant Versus Immune Therapy in Pediatric Severe Aplastic Anemia |
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| Active, not recruiting | N/A | 40 | US | cyclosporine, Matched Unrelated Donor Hematopoietic Stem Cell Transplant, horse anti-thymocyte globulin (ATG), ATGAM, rabbit anti-thymocyte globulin (ATG), Thymoglobulin, methotrexate, fludarabine, cyclophosphamide, low-dose total body irradiation (TBI), Immunosuppressive Therapy (IST) | Michael Pulsipher, MD | Severe Aplastic Anemia | 04/24 | 04/24 | | |
