Sarcoma  >>  Leukine (sargramostim)  >>  Phase 1
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7 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Leukine (sargramostim) / Partner Therap
NCT00000694: A Phase I Trial of Recombinant Human Granulocyte-Macrophage Colony Stimulating Factor (rHuGM-CSF), Recombinant Alpha Interferon and Azidothymidine (AZT) in AIDS-Associated Kaposi's Sarcoma

Completed
1
18
US
Interferon alfa-2b, Zidovudine, Sargramostim
National Institute of Allergy and Infectious Diseases (NIAID)
Sarcoma, Kaposi, HIV Infections
 
08/92
NCT00000681: A Phase I Study of the Combination of Recombinant GM-CSF, AZT, and Chemotherapy (ABV) (Adriamycin, Bleomycin, Vincristine) in AIDS and Kaposi's Sarcoma

Completed
1
24
US
Bleomycin sulfate, Vincristine sulfate, Doxorubicin hydrochloride, Zidovudine, Sargramostim
National Institute of Allergy and Infectious Diseases (NIAID)
Sarcoma, Kaposi, HIV Infections
 
10/93
NCT00027911: Vaccine Therapy and Sargramostim in Treating Patients With Soft Tissue Sarcoma

Terminated
1
US
NY-ESO-1 peptide vaccine, sargramostim
Columbia University, National Cancer Institute (NCI)
Sarcoma
06/05
06/05
NCT00069940: Vaccine Therapy and Sargramostim in Treating Patients With Sarcoma or Brain Tumor

Completed
1
US
sargramostim, telomerase: 540-548 peptide vaccine
Dana-Farber Cancer Institute, National Cancer Institute (NCI)
Brain and Central Nervous System Tumors, Gastrointestinal Stromal Tumor, Sarcoma
08/06
08/08
NCT00623077: MT2004-30: Tomotherapy for Solid Tumors

Terminated
1
23
US
filgrastim, G-CSF, Sargramostim, busulfan, Busulfex, Myleran, etoposide, Eposin, VP-16, ifosfamide, Mitoxana, Ifex, melphalan, Alkeran, thiotepa, stem cell transplantation, HPC infusion, tomotherapy, total marrow irradiation, Mesna, Uromitexan®, Mesnex, Whole lung radiation
Masonic Cancer Center, University of Minnesota
Brain and Central Nervous System Tumors, Kidney Cancer, Liver Cancer, Retinoblastoma, Sarcoma
07/12
10/16
NCT01250470: Vaccine Therapy and Sargramostim in Treating Patients With Malignant Glioma

Completed
1
9
US
Laboratory Biomarker Analysis, Montanide ISA-51/Survivin Peptide Vaccine, Sargramostim, 23-L-Leucinecolony-Stimulating Factor 2, DRG-0012, Leukine, Prokine, rhu GM-CFS, Sagramostim, Sargramostatin
Roswell Park Cancer Institute, National Cancer Institute (NCI)
Anaplastic Astrocytoma, Anaplastic Oligoastrocytoma, Anaplastic Oligodendroglioma, Giant Cell Glioblastoma, Glioblastoma, Gliosarcoma, Mixed Glioma, Recurrent Brain Neoplasm
05/14
05/14
NCT02444546: Wild-Type Reovirus in Combination With Sargramostim in Treating Younger Patients With High-Grade Relapsed or Refractory Brain Tumors

Completed
1
6
US
Laboratory Biomarker Analysis, Sargramostim, 23-L-Leucinecolony-Stimulating Factor 2, DRG-0012, Leukine, Prokine, rhu GM-CFS, Sagramostim, Sargramostatin, Wild-type Reovirus, Reolysin
Mayo Clinic, National Cancer Institute (NCI)
Childhood Astrocytoma, Childhood Atypical Teratoid/Rhabdoid Tumor, Diffuse Intrinsic Pontine Glioma, Glioma, Recurrent Childhood Anaplastic Oligodendroglioma, Recurrent Childhood Brain Neoplasm, Recurrent Childhood Glioblastoma, Recurrent Childhood Medulloblastoma, Recurrent Primitive Neuroectodermal Tumor, Refractory Brain Neoplasm
07/18
11/22

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