Online Trial Tracker - Larvol Sigma

Trial + Data / Events

Status

Region

Interventions

Sponsor

Conditions

Primary compl

Study compl

hydrocortisone / Generic mfg.

NCT02270788: Crenolanib in Combination With Sorafenib in Patients With Refractory or Relapsed Hematologic Malignancies

Completed

Crenolanib, CP-868,596, IND 112201, Sorafenib, Sorafenib tosylate, BAY-43-9006, Nexavar®, methotrexate, hydrocortisone and cytarabine with leucovorin, Triple IT chemotherapy

St. Jude Children's Research Hospital, Arog Pharmaceuticals, Inc., Ohio State University

Acute Myeloid Leukemia

10/16

RELPALL, NCT03515200: Treatment With Combination Chemotherapy for Relapsed or Refractory Acute Lymphoblastic Leukemia

Terminated

Palbociclib Oral Capsule, Ibrance®, Intrathecal Triple Therapy, ITMHA, methotrexate/hydrocortisone/cytarabine, Dexamethasone, Decadron, Bortezomib, Velcade®, Dasatinib, Sprycel®, Doxorubicin, Adriamycin®, Ruxolitinib, Jakafi®

St. Jude Children's Research Hospital, Pfizer

Acute Lymphoblastic Leukemia, in Relapse, Acute Lymphoblastic Leukemia With Failed Remission

07/20

NCT03349281: Pevonedistat With VXLD Chemotherapy for Adolescent/Young Adults With Relapsed/Refractory ALL or Lymphoblastic NHL

Completed

Pevonedistat, TAK-924, MLN4924, Vincristine, Oncovin, VCR, LCR, Dexamethasone, Decadron, Hexadrol, Dexone, Dexameth, PEG-asparaginase, Oncaspar, Pegaspargase, Polyethylene Glycol Conjugated L-asparaginase-H, Doxorubicin, Adriamycin, Cytarabine, ARA-C, Methotrexate, MTX, Amethopterin, Hydrocortisone, Cortisol

Julio Barredo, MD, Takeda

Refractory Acute Lymphoblastic Leukemia, Relapsed Acute Lymphoblastic Leukemia

08/21

10/22

SELCLAX, NCT04898894: Study of Selinexor and Venetoclax in Combination With Chemotherapy in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting

Venetoclax, Venclextra®, ABT-199, Selinexor, KPT-330, Cytarabine, Cytosine arabinoside, Ara-C, Cytosar®, Fludarabine, Fludara®, Fludarabine phosphate, 2-fluoro-ara-AMP, Filgrastim, G-CSF, Methotrexate, MTX, amethopterin, Trexall®, methotrexate/hydrocortisone/cytarabine, ITMHA, Intrathecal triples

St. Jude Children's Research Hospital, Karyopharm Therapeutics Inc, AbbVie, Gateway for Cancer Research

Acute Leukemia of Ambiguous Lineage in Relapse, Acute Myeloid Leukemia, in Relapse, Refractory Acute Leukemia of Ambiguous Lineage, Refractory Acute Myeloid Leukemia

07/23

07/25

NCT06177067: Study of Revumenib, Azacitidine, and Venetoclax in Pediatric and Young Adult Patients With Refractory or Relapsed Acute Myeloid Leukemia

Recruiting

Revumenib, SNDX-5613, Venetoclax, Venclextra®, Azacitidine, VIDAZA®, 5-azacitidine, intrathecal (IT) chemotherapy, ITMHA, methotrexate/hydrocortisone/cytarabine, Cytarabine, Ara-C, Cytosar®, Methotrexate, MTX, Trexall®

St. Jude Children's Research Hospital, Syndax Pharmaceuticals

Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia, Acute Leukemia of Ambiguous Lineage

01/26

07/26

NCT02303821 / 2014-001633-84: Study of Carfilzomib in Combination With Induction Chemotherapy in Children With Relapsed or Refractory Acute Lymphoblastic Leukemia

Active, not recruiting

130

Europe, Canada, US, RoW

Carfilzomib, PR-171, PR171, Kyprolis® (carfilzomib) for Injection, Dexamethasone, Mitoxantrone, PEG-asparaginase, Vincristine, Intrathecal (IT) Methotrexate, Intrathecal Triple Therapy (Intrathecal Cytarabine, Hydrocortisone, and Methotrexate), 6-Mercaptopurine, Cyclophosphamide, Cytarabine, Daunorubicin

Amgen, Therapeutic Advances in Childhood Leukemia & Lymphoma (TACL) - Study Design & Execution Collaborator, Innovative Therapies For Children with Cancer Consortium

Acute Lymphoblastic Leukemia (ALL)

07/24



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