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Serine-Threonine Kinase Inhibitors
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Phase 2
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Phase
N/A
1
2
3
4
Trials
0
7
14
21
28
35
42
49
56
63
70
alvocidib
(DSP-2033) / Sumitomo Pharma
MK-2206
/ Merck (MSD)
sapanisertib
(CB-228) / Calithera
vistusertib
(AZD2014) / AstraZeneca
sotrastaurin
(AEB071) / Novartis
7-Hydroxystaurosporine
(UCN-01) / National Cancer Institute
afuresertib
(LAE002) / Laekna Therap
Fyarro
(nanoparticle albumin-bound rapamycin) / Aadi Biosci
vactosertib
(TEW-7197) / National OncoVenture, Theragen Etex
samotolisib
(LY3023414) / Eli Lilly
ulixertinib
(BVD-523) / BioMed Valley Discoveries
onvansertib
(PCM-075) / Cardiff Oncology
uprosertib
(LAE003) / Laekna Therap
RX208
/ Suzhou NeuPharma, Fosun Pharma
ST266
/ Noveome Biotherap
apitolisib
(GDC-0980) / Roche
riviciclib
(P27600) / Piramal Phytocare
BI2536
/ Boehringer Ingelheim
bimiralisib
(PQR309) / Torqur
indisulam
(E7070) / Eisai
temuterkib
(LY3214996) / Eli Lilly
voxtalisib
(SAR245409) / Sanofi
Hocena
(antroquinonol) / Golden Biotechnology
elraglusib
(9-ING-41) / Actuate Therap
onatasertib
(ATG-008) / BMS
glecirasib
(JAB-21822) / Jacobio Pharma
roniciclib
(BAY1000394) / Bayer
silmitasertib
(CX-4945) / Senhwa Biosci, University of California
tomivosertib
(eFT508) / eFFECTOR Therap
tozasertib
(MK-0457) / Merck (MSD)
ENMD-2076
/ CASI
GLPG3970
/ Galapagos, Gilead
fadraciclib
(CYC065) / Cyclacel
miransertib
(MK-7075) / Merck (MSD)
polyinosinic:polycytidylic acid
(BO-112) / Highlight Therap
seliciclib
(CYC202) / Cyclacel, Cedars-Sinai
zotiraciclib
(TG02) / Cothera Biosci
FX 322
/ Astellas, Korro Bio
RVU120
/ Ryvu Therap
barasertib-HQPA
(AZD2811) / AstraZeneca
fulzerasib
(GFH925) / GenFleet Therap
milciclib
(TZLS-201) / Tiziana Life Sci
niclosamide topical
(ATx 201) / UNION Therap
ocifisertib
(CFI-400945) / Treadwell Therap
sonolisib
(PX 866) / Pfizer
tigilanol tiglate
(EBC-46) / Qbiotics
ABTL0812
/ Ability Pharma
AT9283
/ Otsuka
BI 1701963
/ Boehringer Ingelheim
CINelim
(terameprocol) / Erimos Pharma
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