MD First Research
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 15 Trials 
30 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Beck, James D
NCT04994015: Parkinson's Foundation PD GENEration Genetic Registry

Recruiting
N/A
25000
Canada, US, RoW
Lab Assay for seven genetic variants for Parkinson's Disease
Parkinson's Foundation, Indiana University, Fulgent Genetics, The Parkinson Study Group
Parkinson's Disease
12/24
06/25
NCT05066763: Parkinson's Foundation Surveys

Recruiting
N/A
1000000
US
Non-interventional
Parkinson's Foundation
Parkinson Disease
12/30
12/30
Levine, Todd D
NIMBLE, NCT05070858 / 2020-003272-41: A Study to Examine the Efficacy and Safety of Pozelimab and Cemdisiran Combination Therapy in Adult Patients With Symptomatic Generalized Myasthenia Gravis

Recruiting
3
235
Europe, Canada, Japan, US, RoW
Pozelimab + Cemdisiran, Cemdisiran, ALN-CC5, Placebo, Pozelimab, REGN3918
Regeneron Pharmaceuticals
Generalized Myasthenia Gravis
08/25
03/28
ENSURE-2, NCT05201638: Study to Evaluate the Efficacy, Safety and Tolerability of IMU-838 in Patients With Relapsing Multiple Sclerosis

Recruiting
3
1050
Europe, US, RoW
IMU-838 tablets, Vidofludimus calcium, Placebo matching IMU-838 tablets, Placebo matching vidofludimus calcium
Immunic AG
Multiple Sclerosis, Relapsing-Remitting
10/24
10/32
ENVISION, NCT05310071: A Study to Verify the Clinical Benefit of Aducanumab in Participants With Early Alzheimer's Disease

Active, not recruiting
3
1512
Europe, Canada, Japan, US, RoW
Aducanumab, BIIB037, Aducanumab-avwa, Aduhelm, Placebo
Biogen
Alzheimer's Disease
12/25
10/26
ATLAS, NCT04856982 / 2020-004590-51: A Study of BIIB067 (Tofersen) Initiated in Clinically Presymptomatic Adults With a Confirmed Superoxide Dismutase 1 Mutation

Recruiting
3
150
Europe, Canada, Japan, US, RoW
Tofersen, BIIB067, QALSODY, Placebo
Biogen
Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation
08/27
08/27
ALKIVIA, NCT05523167 / 2021-001277-23: A Study to Investigate the Efficacy and Safety of Efgartigimod PH20 SC in Adult Participants With Active Idiopathic Inflammatory Myopathy.

Recruiting
2/3
240
Europe, Canada, US, RoW
EFG PH20 SC, PBO
argenx, argenx BV
Active Idiopathic Inflammatory Myopathy, Myositis, Dermatomyositis, Polymyositis, Immune-Mediated Necrotizing Myopathy, Antisynthetase Syndrome
12/26
02/27
NCT05650567: Study of M5049 in DM and PM Participants (NEPTUNIA)

Recruiting
2
40
Europe, US, RoW
M5049 high dose, Enpatoran, Placebo
EMD Serono Research & Development Institute, Inc., Merck KGaA, Darmstadt, Germany
Dermatomyositis, Polymyositis
07/24
12/24
ARDA+, NCT05405361 / 2021-004998-32: A Clinical Trial to Investigate the Long-term Safety and Tolerability, Efficacy, Pharmacodynamics, Pharmacokinetics, and Immunogenicity of ARGX-117 in Adults With Multifocal Motor Neuropathy

Recruiting
2
48
Europe, Canada, US
ARGX-117, Placebo
argenx, argenx BV
Multifocal Motor Neuropathy (MMN)
11/25
10/26
CELIA, NCT05399888: A Study to Learn About the Safety of BIIB080 and Whether it Can Improve Symptoms of Participants With Mild Cognitive Impairment Due to Alzheimer's Disease (AD) or Mild AD Dementia Between 50 to 80 Years of Age

Recruiting
2
735
Europe, Canada, Japan, US, RoW
BIIB080, ISIS 814907, BIIB080-matching placebo
Biogen
Mild Cognitive Impairment Due to Alzheimer's Disease, Alzheimer's Disease Dementia
11/27
02/30
NCT04700722: Synuclein-One Study

Completed
N/A
428
US
Skin Biopsy
CND Life Sciences
Parkinson Disease, Multiple System Atrophy, Dementia With Lewy Bodies, Pure Autonomic Failure
12/22
11/23
NCT05479552: A Diagnostic Test for Dementia With Lewy Bodies

Recruiting
N/A
80
US
Syn-One Test
CND Life Sciences, National Institute on Aging (NIA)
MCI-AD, Early Stage Alzheimer's Disease, MCI-DLB, Early Stage Dementia With Lewy Bodies
03/24
03/24
NCT05757206: The Syn-Sleep Study

Recruiting
N/A
80
US
Syn-One Test
CND Life Sciences
REM Sleep Behavior Disorder (iRBD)
08/25
08/25
Jensen, Alexandra D
LIVERCARE, NCT03253536: Prospective Observational Trial to Evaluate Quality of Life After Stereotactic Ablative Radiation Therapy in Patients With Hepatocellular Carcinoma

Recruiting
N/A
100
Europe
observational
Ludwig-Maximilians - University of Munich
Hepatocellular Cancer, Quality of Life, Stereotactic Body Radiation Therapy, Observational
07/22
07/27
NCT05757206: The Syn-Sleep Study

Recruiting
N/A
80
US
Syn-One Test
CND Life Sciences
REM Sleep Behavior Disorder (iRBD)
08/25
08/25
Alcalay, Roy
PDGENE, NCT04057794: PDGeneration: Mapping the Future of Parkinson's Disease

Active, not recruiting
N/A
1982
US
Lab Assay for seven genetic variants for Parkinson's Disease
Parkinson's Foundation, Fulgent Laboratories, Indiana University, The Parkinson Study Group, Navitas Clinical Research, Inc
Parkinson's Disease and Parkinsonism
12/21
04/25
NCT04239079: Autoimmune Features of Neurodegenerative Disorders

Recruiting
N/A
120
US
Columbia University
Parkinson Disease, Alzheimer Disease, Mild Cognitive Impairment
06/24
06/24
NCT05718739: Assessing and Understanding Freezing of Gait at Home: FOG@Home

Not yet recruiting
N/A
30
RoW
AX6 6-axis logging accelerometer, AX6
Tel-Aviv Sourasky Medical Center
Parkinson Disease, Freezing of Gait
05/24
12/24
NCT04994015: Parkinson's Foundation PD GENEration Genetic Registry

Recruiting
N/A
25000
Canada, US, RoW
Lab Assay for seven genetic variants for Parkinson's Disease
Parkinson's Foundation, Indiana University, Fulgent Genetics, The Parkinson Study Group
Parkinson's Disease
12/24
06/25
Pandey, Hemant
TRAILBLAZER-ALZ 6, NCT05738486: A Study of Different Donanemab (LY3002813) Dosing Regimens in Adults With Early Alzheimer's Disease

Recruiting
3
800
Europe, US
Donanemab, LY3002813, Placebo
Eli Lilly and Company
Alzheimer's Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders
06/24
05/25
RETHINK-1, NCT04994483: Simufilam 100 mg for Mild-to-Moderate Alzheimer's Disease

Active, not recruiting
3
750
Canada, US, RoW
Simufilam, PTI-125, Placebo
Cassava Sciences, Inc., Premier Research Group plc
Alzheimer Disease
10/24
10/24
TRAILRUNNER-ALZ 1, NCT05463731: A Study of Remternetug (LY3372993) in Participants With Alzheimer's Disease

Recruiting
3
600
Japan, US
Remternetug (IV), LY3372993, Remternetug (SC), Placebo
Eli Lilly and Company
Alzheimer's Disease
10/25
10/26
NCT04845178: Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adults

Active, not recruiting
2
797
Canada, US, RoW
ABP-450, prabotulinumtoxinA, Placebo, 0.9% sodium chloride, saline
AEON Biopharma, Inc., PPD
Migraine
06/24
09/24
NCT04994015: Parkinson's Foundation PD GENEration Genetic Registry

Recruiting
N/A
25000
Canada, US, RoW
Lab Assay for seven genetic variants for Parkinson's Disease
Parkinson's Foundation, Indiana University, Fulgent Genetics, The Parkinson Study Group
Parkinson's Disease
12/24
06/25
NCT05757206: The Syn-Sleep Study

Recruiting
N/A
80
US
Syn-One Test
CND Life Sciences
REM Sleep Behavior Disorder (iRBD)
08/25
08/25
Guardado, Sean
NCT04845178: Investigation of Safety and Efficacy of ABP-450 for Migraine Prevention in Adults

Active, not recruiting
2
797
Canada, US, RoW
ABP-450, prabotulinumtoxinA, Placebo, 0.9% sodium chloride, saline
AEON Biopharma, Inc., PPD
Migraine
06/24
09/24
NCT04994015: Parkinson's Foundation PD GENEration Genetic Registry

Recruiting
N/A
25000
Canada, US, RoW
Lab Assay for seven genetic variants for Parkinson's Disease
Parkinson's Foundation, Indiana University, Fulgent Genetics, The Parkinson Study Group
Parkinson's Disease
12/24
06/25
Gomez, Aleksander
NCT04994015: Parkinson's Foundation PD GENEration Genetic Registry

Recruiting
N/A
25000
Canada, US, RoW
Lab Assay for seven genetic variants for Parkinson's Disease
Parkinson's Foundation, Indiana University, Fulgent Genetics, The Parkinson Study Group
Parkinson's Disease
12/24
06/25
NCT01574053: Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

Recruiting
N/A
35000
Europe, Canada, US, RoW
CHDI Foundation, Inc.
Huntington's Disease
01/62
01/62
Rush, Angela
NCT05757206: The Syn-Sleep Study

Recruiting
N/A
80
US
Syn-One Test
CND Life Sciences
REM Sleep Behavior Disorder (iRBD)
08/25
08/25

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