| Luketich, James D |
NCT01345539: Radiosurgery for Patients With Oligometastatic Disease at Initial Presentation |
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| Terminated | 2 | 24 | US | Stereotactic Radiosurgery (SRS), CyberKnife, Trilogy, True Beam, Chemotherapy | Steven Burton | Oligometastatic Disease | 05/22 | 10/22 | | |
NCT03740542: Pyloroplasty Versus No Pyloroplasty in Patients Undergoing Esophagectomy |
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| Active, not recruiting | N/A | 140 | US | Esophagectomy, Pyloroplasty | University of Pittsburgh | Esophagectomy | 02/23 | 01/25 | | |
NCT05591053: Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans |
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| Recruiting | N/A | 70 | US | ActivSight | Activ Surgical, University of Pittsburgh Medical Center, West Penn Allegheny Health System | Esophagus Cancer, Esophageal Cancer, Esophageal Neoplasms, Esophageal Diseases, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Esophagus SCC, Esophagus Tumor, Esophagus Adenocarcinoma, Esophagus Neoplasm | 01/25 | 01/25 | | |
| Recruiting | N/A | 6000 | US | Biopsy of the major carinal area, Biopsy of abnormal & suspicious areas of the bronchial tree, Evaluation of the tumor for DNA mutations, Bronchoalveolar Lavage (BAL) for cytokine analysis, Correlation of flow cytometric & RT PCR for TNM stage, Analysis of lymph nodes | University of Pittsburgh, National Institutes of Health (NIH) | Lung Cancer | 12/50 | 12/50 | | |
NCT00260572: Outcomes After Medical and Surgical Treatment of Gastroesophageal Reflux Disease |
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| Recruiting | N/A | 2500 | US | Questionnaires to evaluate QOL, Questionnaires to evaluate heartburn and quality of life, Questionnaire to evaluate satisfaction with treatment, Questionnaire to evaluate presence or absence of pain | University of Pittsburgh | Gastroesophageal Reflux Disease | 12/50 | 12/50 | | |
NCT00260559: Outcomes After Esophagectomy with a Focus on Minimally Invasive Esophagectomy and Quality of Life |
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| Recruiting | N/A | 3500 | US | Questionnaires | University of Pittsburgh | Esophagectomy, Esophageal Cancer | 12/50 | 12/50 | | |
| Recruiting | N/A | 7000 | US | Survey of client health, personal habits, family history, Blood specimen for non-DNA and DNA parts, Biopsy of esophageal/stomach tissue, lymph nodes, tumor, Biopsies, oral (saliva) and/or secretions, washings or mucosal scrapings/brushing from routine clinical surveillance endoscopies | University of Pittsburgh, National Institutes of Health (NIH), National Cancer Institute (NCI) | Esophageal Cancer, Gastroesophageal Reflux Disease (GERD), Esophageal Diseases, Hiatal Hernia, Esophageal Achalasia | 12/50 | 12/50 | | |
| Buysse, Daniel J |
| Completed | 4 | 155 | US | Zolpidem, Ambien, Internet Cognitive Behavioral Therapy for Insomnia (CBT-I), SHUTi, Trazodone, Desyrel | California Pacific Medical Center Research Institute, Patient-Centered Outcomes Research Institute, University of Pittsburgh, University of Arizona, University of Virginia, University of Illinois at Chicago | Chronic Insomnia | 06/24 | 06/24 | | |
SLAB, NCT05604222: Effect of Behavioral Sleep Intervention on Lower Urinary Tract Symptoms in Older Women |
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| Recruiting | 4 | 120 | US | Mirabegron 50 MG, Myrbetriq, Brief Behavioral Treatment for Insomnia, BBTI | Shachi Tyagi, National Institute on Aging (NIA) | Urgency Urinary Incontinence, Nocturia | 05/26 | 03/27 | | |
ALPS, NCT05138848: Time-in-bed Restriction in Older Adults With Sleep Difficulties With and Without Risk for Alzheimer's Disease |
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| Recruiting | 1 | 116 | US | Time in Bed Restriction, Sleep Schedule | University of Pittsburgh, National Institute on Aging (NIA) | Alzheimer Disease, Late Onset, Mild Cognitive Impairment, Sleep, Cognitive Change, Amyloid | 05/26 | 05/26 | | |
| Not yet recruiting | N/A | 420 | US | Treatment As Usual, Active Condition, Active Comparator | University of Pittsburgh, Emory University, University of California, Berkeley, University of California, Los Angeles, Augusta University, National Institutes of Health (NIH), National Institute of Mental Health (NIMH) | Depression, Suicidality, Sleep | 08/29 | 08/30 | | |
| Jacobs, Charlotte D |
| Recruiting | 3 | 272 | Europe, Canada, US, RoW | Lung Surgery, SR, Radiation therapy, SAbR | University of Texas Southwestern Medical Center | Non-Small Cell Lung Cancer | 12/28 | 12/28 | | |
| Ritterband, Lee M |
| Recruiting | 2 | 160 | US | Migraine Manager | Children's Hospital Medical Center, Cincinnati | Migraine, Migraine Disorders | 04/25 | 05/25 | | |
NCT05030753: iSIPsmarter: An RCT to Evaluate the Efficacy of a Technology-based Behavioral Intervention to Reduce Sugary Beverages Among Rural Appalachian Adults |
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| Active, not recruiting | N/A | 245 | US | iSIPsmarter, Patient Education (PE) | University of Virginia, University of North Carolina | Diet Habit, Sugar-Sweetened Beverages | 12/23 | 12/24 | | |
NCT06184737: iSIPsmarter: A Pilot RCT to Evaluate a Web-based Behavioral Intervention to Reduce Sugary Beverages Among Black Adults |
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| Recruiting | N/A | 24 | US | iSIPsmarter, Patient Education (PE) | University of Virginia, University of North Carolina | Diet Habit, Sugar-Sweetened Beverages | 08/25 | 01/26 | | |
| Smith, Kenneth J |
| Recruiting | 4 | 45 | Europe | Semaglutide Pen Injector [Ozempic], Very-low Calorie Diet | University of Nottingham, Medical Research Council | Type 2 Diabetes Mellitus in Obese | 07/23 | 07/23 | | |
PoEMS, NCT05997095: Post-operative Electrical Muscle Stimulation to Stimulate Muscle Protein Synthesis in Humans |
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| Active, not recruiting | N/A | 10 | Europe | Neuromuscular electrical stimulation (NMES/0 | University of Nottingham | Skeletal Muscle Atrophy | 09/24 | 12/24 | | |
NCT04185935: Molecular Genetics Studies of Cancer Patients and Their Relatives |
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| Recruiting | N/A | 999999 | US, RoW | Biospecimen Collection, Questionnaire Administration | City of Hope Medical Center, National Cancer Institute (NCI) | Malignant Neoplasm | 08/33 | 08/33 | | |
| Slaughter, Mark |
AMIOMEND, NCT06730828: Amiodarone-Infused CardiaMend Patches for the Prevention of New-Onset POAF in Cardiac Surgery Subjects |
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| Recruiting | 1/2 | 80 | US | The intervention includes Amiodarone-Infused CardiaMend patches (70mg, 150mg and 300mg) | Helios Cardio Inc. | Atrial Fibrillation, Postoperative | 11/25 | 05/26 | | |
COMPETENCE, NCT01187368: Prospective Multi-Center Randomized Study for Evaluating the EVAHEART®2 Left Ventricular Assist System |
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| Suspended | N/A | 399 | US | EVAHEART Left Ventricular Assist System (LVAS), EVA2, HeartMate 3, HM3 | Evaheart, Inc. | Heart Failure | 07/27 | 07/28 | | |
| Recruiting | N/A | 650 | Europe, Canada, Japan, US, RoW | Medtronic Evolut PRO+ TAVR System, or Evolut FX TAVR System, and guideline-directed management and therapy (GDMT) | Medtronic Cardiovascular | Moderate Aortic Valve Stenosis | 02/26 | 12/34 | | |
NCT05427370: The Canadian CABG or PCI in Patients With Ischemic Cardiomyopathy Trial (STICH3C) |
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| Recruiting | N/A | 754 | Europe, Canada, US, RoW | Revascularization by PCI, Revascularization by CABG | Sunnybrook Health Sciences Centre, Canadian Institutes of Health Research (CIHR), Weill Medical College of Cornell University | Coronary Artery Disease, Heart Failure Systolic | 04/29 | 12/29 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
| Toler, Becky |
NCT05113381: The Purpose of This Study is to Determine Whether CerebroFlo™ EVD Catheter is Effective During the Treatment of IVH |
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| Recruiting | N/A | 109 | US | CerebroFlo™ EVD Catheter | Integra LifeSciences Corporation | Intraventricular Hemorrhage, Subarachnoid Hemorrhage | 10/24 | 12/24 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
| Robich, Michael |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
| Sultan, Ibrahim |
| Active, not recruiting | N/A | 800 | Europe, Canada, US, RoW | Evolut™ PRO and Evolut™ PRO+ System (Evolut™ FX System for the addendum) | Medtronic Cardiovascular | Symptomatic Aortic Stenosis | 12/23 | 12/24 | | |
| Recruiting | N/A | 150 | US | Penditure™ Left Atrial Appendage (LAA) Exclusion System | Medtronic Cardiac Surgery | Left Atrial Appendage Exclusion | 11/25 | 02/29 | | |
| Active, not recruiting | N/A | 115 | US | AMDS | Artivion Inc., Syneos Health | Acute Aortic Dissection | 12/23 | 12/29 | | |
NCT03735667: ACURATE IDE: Safety and Effectiveness Study of ACURATE Valve for Transcatheter Aortic Valve Replacement |
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| Active, not recruiting | N/A | 1948 | Canada, US | ACURATE neo2™ Transfemoral TAVR System, Medtronic CoreValve TAVR System, Edwards SAPIEN 3 TAVR System, ACURATE Prime™ Transfemoral TAVR System XL | Boston Scientific Corporation | Aortic Stenosis | 06/24 | 09/34 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MitraClip™ device implantation, Mitral Valve Repair Surgery | Abbott Medical Devices | Mitral Valve Regurgitation | 04/26 | 04/34 | | |
APOLLO, NCT03242642: Transcatheter Mitral Valve Replacement With the Medtronic Intrepid™ TMVR System in Patients With Severe Symptomatic Mitral Regurgitation. |
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| Recruiting | N/A | 1056 | Europe, Canada, US | Medtronic Intrepid Transcatheter Mitral Valve Replacement System (TMVR) | Medtronic Cardiovascular | Mitral Valve Regurgitation | 10/26 | 09/36 | | |
ENVISION, NCT05932615: IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation |
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| Enrolling by invitation | N/A | 1500 | Canada, US | Navitor Transcatheter Aortic Valve Implantation (TAVI) System, Any Commercially Available Transcatheter Aortic Valve (CAV) System | Abbott Medical Devices | Aortic Valve Stenosis, Heart Valve Diseases, Aortic Valve Disease, Heart Disease Structural Disorder | 04/27 | 04/36 | | |
| Recruiting | N/A | 500 | Europe, Canada, US | MITRIS RESILIA Mitral Valve, Model 11400M | Edwards Lifesciences | Mitral Stenosis, Mitral Valve Insufficiency | 01/28 | 12/35 | | |
| Recruiting | N/A | 1100 | US | TEVAR, Guideline directed medical therapy and surveillance of dissection | Duke University, The University of Texas Health Science Center, Houston, State University of New York - Downstate Medical Center, Oregon Health and Science University, National Heart, Lung, and Blood Institute (NHLBI) | Type B Aortic Dissection | 06/30 | 06/30 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
| Recruiting | N/A | 200 | Europe, US | Thoraflex Hybrid, RelayPro NBS | Vascutek Ltd., Bolton Medical | Thoracic Diseases, Aortic Aneurysm, Aortic Dissection, Thoracic Aortic Aneurysm, Thoracic Aortic Dissection | 12/35 | 12/36 | | |
| Robinson, Zyriah |
| Recruiting | 3 | 3200 | Europe, Canada, US | Antiplatelet-only strategy, Oral Anticoagulant plus background antiplatelet therapy | Icahn School of Medicine at Mount Sinai, National Heart, Lung, and Blood Institute (NHLBI), Vanderbilt University Medical Center | Atrial Fibrillation, Stroke, Bleeding | 06/25 | 06/25 | | |
SCAD, NCT06310174: Study Examining the Effect of a Novel Cannulation Knife on User Satisfaction and Common Central Venous Catheter Insertion Complications |
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| Recruiting | N/A | 144 | US | | Johns Hopkins University | Central Venous Catheter Exit Site Infection | 03/26 | 05/27 | | |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
| Valchar, Kristin Konopka |
| Recruiting | N/A | 6500 | Europe, Canada, US | AtriClip LAA Exclusion System | AtriCure, Inc., Population Health Research Institute | Ischemic Stroke, Systemic Embolism | 12/31 | 04/32 | | |
