| O'Toole, Robert |
TOBRA, NCT04597008: Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: |
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| Recruiting | 3 | 1900 | US | Treatment group, Treatment, Control group, Control | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 06/25 | 12/26 | | |
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT |
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| Recruiting | 3 | 1200 | US | Standard of care, Vancomycin and Tobramycin | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 09/24 | 03/25 | | |
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation |
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| Recruiting | 3 | 250 | US | Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics | Major Extremity Trauma Research Consortium, United States Department of Defense | Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect | 09/25 | 09/26 | | |
MBTK, NCT04047030: The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma |
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| Recruiting | N/A | 450 | US | None- Observational Study | Major Extremity Trauma Research Consortium | Gait | 12/23 | 08/24 | | |
NCT05595148: Immediate Weightbearing Vs Delayed Weightbearing |
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| Enrolling by invitation | N/A | 100 | US | Immediate WBAT, No Intervention: Delayed WBAT | University of Maryland, Baltimore | Rehabilitation | 12/25 | 12/25 | | |
NCT04028414: Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures |
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| Active, not recruiting | N/A | 450 | US | Early Weight Bearing | Major Extremity Trauma Research Consortium | Rehabilitation | 10/24 | 03/25 | | |
| Slobogean, Gerard |
| Completed | 4 | 8485 | Canada, US | DuraPrep, ChloraPrep | University of Maryland, Baltimore, McMaster University, Patient-Centered Outcomes Research Institute | Surgical Site Infection, Unplanned Fracture-Related Reoperation, Open Appendicular Fracture, Closed Lower Extremity Fracture, Pelvic Fracture | 03/23 | 02/24 | | |
| Recruiting | 3 | 312 | Canada, US | Antibiotic Cement Bead Pouch, Negative Pressure Wound Therapy | University of Maryland, Baltimore, McMaster University | Open Tíbia Fracture | 03/25 | 10/25 | | |
NCT04403204: ICG Fluorescence Imaging in Post-traumatic Infection |
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| Recruiting | N/A | 170 | US | Immunofluorescence Imaging, DCE-MRI | Dartmouth-Hitchcock Medical Center, Dartmouth College, University of Maryland, Baltimore, University of California, Irvine | Trauma Injury | 12/24 | 12/25 | | |
COPE, NCT04274530: Cognitive Behavioural Therapy to Optimize Post-Operative Recovery Trial |
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| Recruiting | N/A | 1000 | Canada, US | Cognitive Behavioural Therapy, CBT | McMaster University, Orthopaedic Trauma Association, Canadian Institutes of Health Research (CIHR) | Pain, Postoperative, Pain, Acute, Pain, Chronic, Fractures, Closed, Fractures, Open | 08/25 | 08/25 | | |
NCT06249126: Primary Subtalar Arthrodesis for Calcaneal Fractures |
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| Recruiting | N/A | 218 | US | Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA), Open Reduction Internal Fixation (ORIF) only | Wake Forest University Health Sciences | Calcaneus Fracture | 12/26 | 12/26 | | |
NCT04416412: ICG Fluorescence Imaging in Open Fracture Trauma Patients |
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| Recruiting | N/A | 180 | US | Immunofluorescence Imaging | Dartmouth-Hitchcock Medical Center, Dartmouth College, United States Department of Defense, Brigham and Women's Hospital, University of California, Irvine, University of Maryland, Baltimore | Trauma Injury | 01/25 | 01/26 | | |
| Recruiting | N/A | 1100 | Europe, Canada, US, RoW | Accelerated medical clearance and surgery | Population Health Research Institute, Canadian Institutes of Health Research (CIHR), National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Hip Fractures, Myocardial Injury | 02/27 | 05/27 | | |
NCT05947058: Minimally Displaced Femoral Neck Fracture Pilot Study |
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| Recruiting | N/A | 40 | Europe, Canada, US | Arthroplasty, Internal Fixation | University of Maryland, Baltimore, Orthopaedic Trauma Association, McMaster University, University of Southern California | Femoral Neck Fractures | 12/25 | 12/25 | | |
| Matuszewski, Paul E |
NCT05421741: Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial |
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| Recruiting | 4 | 484 | US | Antibiotic coated intramedullary Nail, Local Gentamicin 560 Powder, Vancomycin 2gm Liquid, Standard Intramedullary Nail | Wake Forest University Health Sciences | Osteomyelitis Tibia, Tibial Fractures, Open Tibia Fracture | 12/26 | 12/27 | | |
NCT05766670: Intramedullary Calcium Sulfate Antibiotic Depot |
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| Recruiting | 3 | 497 | US | Vancomycin Hydrochloride, antibacterial prescription medicine, Gentamicin, injection is used to treat certain serious infections that are caused by bacteria such as meningitis, Standard Intramedullary Nail, metal rod that is inserted into the medullary cavity of a bone and across the fracture in order to provide a solid support for the fractured bone | Wake Forest University Health Sciences | Open tíbia Fracture, Osteomyelitis Tibia, Tibial Fractures | 01/27 | 01/28 | | |
MBTK, NCT04047030: The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma |
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| Recruiting | N/A | 450 | US | None- Observational Study | Major Extremity Trauma Research Consortium | Gait | 12/23 | 08/24 | | |
NCT06249126: Primary Subtalar Arthrodesis for Calcaneal Fractures |
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| Recruiting | N/A | 218 | US | Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA), Open Reduction Internal Fixation (ORIF) only | Wake Forest University Health Sciences | Calcaneus Fracture | 12/26 | 12/26 | | |
NCT06024304: InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery |
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| Not yet recruiting | N/A | 30 | NA | Synthes TFNA, Trigen InterTAN | Paul E. Matuszewski | Fracture of Hip | 01/26 | 01/27 | | |
| Pensy, Raymond |
| Active, not recruiting | 3 | 395 | Canada, US | Lactose Placebo, Ketotifen Fumarate 2mg, Ketotifen Fumarate 5mg | University of Calgary, United States Department of Defense | Elbow Fracture, Elbow Injury, Elbow Dislocation | 09/24 | 12/25 | | |
| Manson, Theodore |
NCT04630262: ATTUNE Cementless FB Tibial Base Clinical Study |
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| Terminated | N/A | 80 | US | ATTUNE Cementless CR Fixed Bearing, ATTUNE Cementless PS Fixed Bearing | DePuy Orthopaedics | Osteoarthritis of the Knee | 03/23 | 03/23 | | |
| Sciadini, Marcus |
NCT04730739: FastFrame Knee Spanning and Damage Control Kit PMCF |
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| Terminated | N/A | 36 | US | FastFrame External Fixation System - Knee Spanning or Damage Control Kit | Zimmer Biomet | Fracture, Fractures, Bone, Fractures, Closed, Fractures, Open | 06/24 | 07/24 | | |
| Howe, Andrea |
NCT06249126: Primary Subtalar Arthrodesis for Calcaneal Fractures |
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| Recruiting | N/A | 218 | US | Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA), Open Reduction Internal Fixation (ORIF) only | Wake Forest University Health Sciences | Calcaneus Fracture | 12/26 | 12/26 | | |
| Rudnicki, Joshua |
| No trials found |
