| Stein, Deborah |
| Recruiting | 2 | 20 | US | Emergency preservation and resuscitation, Standard resuscitation | University of Maryland, Baltimore, Cook County Health | Cardiac Arrest From Trauma | 12/25 | 12/25 | | |
| Completed | N/A | 69 | US | Acupuncture | University of Maryland, Baltimore, United States Department of Defense | Spinal Cord Injuries | 12/22 | 02/23 | | |
NCT05780918: A Communication Tool to Improve Communication in the ICU |
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| Enrolling by invitation | N/A | 7600 | US | Best Case/Worst Case-ICU Communication Tool | University of Wisconsin, Madison, National Institute on Aging (NIA), Shock Trauma - University of Maryland Medical Center, University of California, Davis, Harborview Injury Prevention and Research Center, Lehigh Valley Health Network, Grady Memorial Hospital, Froedtert Hospital, University of Alabama at Birmingham, Rhode Island Hospital, American College of Surgeons, Coalition for National Trauma Research | Serious Injury, Communication | 09/25 | 12/25 | | |
| Castillo, Renan |
TOBRA, NCT04597008: Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: |
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| Recruiting | 3 | 1900 | US | Treatment group, Treatment, Control group, Control | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 06/25 | 12/26 | | |
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT |
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| Recruiting | 3 | 1200 | US | Standard of care, Vancomycin and Tobramycin | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 09/24 | 03/25 | | |
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation |
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| Recruiting | 3 | 250 | US | Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics | Major Extremity Trauma Research Consortium, United States Department of Defense | Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect | 09/25 | 09/26 | | |
UNION, NCT05143476: Serum-Protein-Based Indices for the Progression of Fracture Healing and Nonunion |
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| Active, not recruiting | N/A | 45 | US | | Major Extremity Trauma Research Consortium, United States Department of Defense | Humerus Fractures | 05/24 | 09/24 | | |
| O'Toole, Robert |
TOBRA, NCT04597008: Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: |
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| Recruiting | 3 | 1900 | US | Treatment group, Treatment, Control group, Control | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 06/25 | 12/26 | | |
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT |
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| Recruiting | 3 | 1200 | US | Standard of care, Vancomycin and Tobramycin | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 09/24 | 03/25 | | |
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation |
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| Recruiting | 3 | 250 | US | Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics | Major Extremity Trauma Research Consortium, United States Department of Defense | Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect | 09/25 | 09/26 | | |
MBTK, NCT04047030: The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma |
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| Recruiting | N/A | 450 | US | None- Observational Study | Major Extremity Trauma Research Consortium | Gait | 12/23 | 08/24 | | |
NCT05595148: Immediate Weightbearing Vs Delayed Weightbearing |
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| Enrolling by invitation | N/A | 100 | US | Immediate WBAT, No Intervention: Delayed WBAT | University of Maryland, Baltimore | Rehabilitation | 12/25 | 12/25 | | |
NCT04028414: Effects of Early Weight Bearing on Rehabilitation Outcomes in Patients With Traumatic Ankle and Tibial Plateau Fractures |
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| Active, not recruiting | N/A | 450 | US | Early Weight Bearing | Major Extremity Trauma Research Consortium | Rehabilitation | 10/24 | 03/25 | | |
| Allen, Lauren |
NCT05881564: Blood Conservation in Patients (3.5-12kg) Undergoing Congenital Cardiac Surgery |
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| Recruiting | N/A | 150 | US | blood use for priming cardiopulmonary bypass circuit, clear prime for cardiopulmonary bypass | Augusta University | Congenital Heart Disease | 05/25 | 05/26 | | |
| Matuszewski, Paul E |
NCT05421741: Prophylactic Antibiotic Coated Nail to Prevent Infection: A Clinical Trial |
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| Recruiting | 4 | 484 | US | Antibiotic coated intramedullary Nail, Local Gentamicin 560 Powder, Vancomycin 2gm Liquid, Standard Intramedullary Nail | Wake Forest University Health Sciences | Osteomyelitis Tibia, Tibial Fractures, Open Tibia Fracture | 12/26 | 12/27 | | |
NCT05766670: Intramedullary Calcium Sulfate Antibiotic Depot |
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| Recruiting | 3 | 497 | US | Vancomycin Hydrochloride, antibacterial prescription medicine, Gentamicin, injection is used to treat certain serious infections that are caused by bacteria such as meningitis, Standard Intramedullary Nail, metal rod that is inserted into the medullary cavity of a bone and across the fracture in order to provide a solid support for the fractured bone | Wake Forest University Health Sciences | Open tÃbia Fracture, Osteomyelitis Tibia, Tibial Fractures | 01/27 | 01/28 | | |
MBTK, NCT04047030: The Mobility Toolkit: Electronically Augmented Assessment of Functional Recovery Following Lower-extremity Trauma |
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| Recruiting | N/A | 450 | US | None- Observational Study | Major Extremity Trauma Research Consortium | Gait | 12/23 | 08/24 | | |
NCT06249126: Primary Subtalar Arthrodesis for Calcaneal Fractures |
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| Recruiting | N/A | 218 | US | Primary Fusion (Open Reduction Internal Fixation (ORIF) + Primary Subtalar Arthrodesis (PSTA), Open Reduction Internal Fixation (ORIF) only | Wake Forest University Health Sciences | Calcaneus Fracture | 12/26 | 12/26 | | |
NCT06024304: InterTAN: Integrated Dual Screw Design Improve Biomechanics/Function Following Fixation Surgery |
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| Not yet recruiting | N/A | 30 | NA | Synthes TFNA, Trigen InterTAN | Paul E. Matuszewski | Fracture of Hip | 01/26 | 01/27 | | |
| Carlini, Anthony |
TOBRA, NCT04597008: Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: |
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| Recruiting | 3 | 1900 | US | Treatment group, Treatment, Control group, Control | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 06/25 | 12/26 | | |
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT |
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| Recruiting | 3 | 1200 | US | Standard of care, Vancomycin and Tobramycin | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 09/24 | 03/25 | | |
| Degani, Yasmin |
TOBRA, NCT04597008: Topical Antibiotic Therapy to Reduce Infection After Operative Treatment of Fractures At High Risk of Infection: |
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| Recruiting | 3 | 1900 | US | Treatment group, Treatment, Control group, Control | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 06/25 | 12/26 | | |
NCT04678154: Evaluation of a New Strategy for Protocolized Antibiotic Care for Severe Open Fractures: SEXTANT |
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| Recruiting | 3 | 1200 | US | Standard of care, Vancomycin and Tobramycin | Major Extremity Trauma Research Consortium, United States Department of Defense | Post Operative Surgical Site Infection | 09/24 | 03/25 | | |
POvIV2, NCT05699174: PO vs IV Antibiotics for the Treatment of Infected Nonunion of Fractures After Fixation |
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| Recruiting | 3 | 250 | US | Standard of Care PO (oral) antibiotics, Standard of Care Intravenous (IV) antibiotics | Major Extremity Trauma Research Consortium, United States Department of Defense | Infections, Infected Wound, Nonunion of Fracture, Injury Leg, Amputation, Internal Fixation; Complications, Infection or Inflammation, Fracture, Lower Extremity Fracture, Antibiotic Side Effect | 09/25 | 09/26 | | |
