University Hospital Maastricht
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 53 Trials 
18 Trials

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Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Theunissen, Koen
TECTONIC, NCT06477783: Study on the Clinical Efficacy of Teclistamab

Recruiting
N/A
100
Europe
Teclistamab, Tecvayli
Universitaire Ziekenhuizen KU Leuven, Janssen Pharmaceutica
Multiple Myeloma, Hematologic Diseases
09/27
09/27
koeveringe, Gommert van
VENUS, NCT04114266: Registry for Patients Undergoing AUS Surgery for Female SUI Due to ISD

Active, not recruiting
N/A
180
Europe, RoW
Questionnaires on Urinary Incontinence-, Sex Function- and Quality of Life (ICIQ-UI-SF, ICIQ-FLUTSsex, ICIQ-LUTSqol, PGI-I)
European Association of Urology Research Foundation, Boston Scientific Corporation
Urinary Incontinence, Urinary Incontinence, Stress, Lower Urinary Tract Symptoms, Urination Disorders, Urologic Diseases
06/25
12/26
Nuijts, Rudy MMA
NCT04632784: Clinical Trial With Artiflex Presbyopic

Recruiting
N/A
140
Europe, RoW
Artiflex Presbyopic implantation
Ophtec BV
Presbyopia, Ametropia, Refractive Errors, Myopia, Hyperopia
07/23
07/25
Jobe, Blair A
NCT05591053: Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans

Recruiting
N/A
70
US
ActivSight
Activ Surgical, University of Pittsburgh Medical Center, West Penn Allegheny Health System
Esophagus Cancer, Esophageal Cancer, Esophageal Neoplasms, Esophageal Diseases, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Esophagus SCC, Esophagus Tumor, Esophagus Adenocarcinoma, Esophagus Neoplasm
01/25
01/25
Bouvy, Nicole D
MARS, NCT05424484: Mesh Augmented Reinforcement of Abdominal Wall Suture Line to Limit the Rate of Incisional Hernia Occurrence

Recruiting
N/A
120
Europe, RoW
Self-Gripping Resorbable Mesh
Medtronic - MITG
Incisional Hernia, Incisional Hernia of Midline of Abdomen, Midline Laparotomy
05/25
09/28
Vernooy, Kevin
NCT04863664: Lead EvaluAtion for Defibrillation and Reliability (LEADR) / Lead Evaluation for Defibrillation and Reliability in Left Bundle Branch Area Pacing (LEADR LBBAP)

Recruiting
N/A
975
Europe, Canada, Japan, US, RoW
Defibrillation (RV Implant), Defibrillation (LBBAP Implant)
Medtronic Cardiac Rhythm and Heart Failure
Tachyarrhythmia
06/25
02/26
CRT-DRIVE, NCT05327062: Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment

Recruiting
N/A
150
Europe, US
CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment
XSpline S.p.A.
Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block
03/25
09/25
NCT04831125: Conduction System Pacing International Registry (CONSPIRE)

Recruiting
N/A
1000
Europe, US
Data collection
University of Chicago, Biotronik SE & Co. KG
Bradyarrhythmia, Heart Failure
04/25
04/25
LEAP-pilot, NCT04595487: LVSP vs RVP in Patients With AV Conduction Disorders

Recruiting
N/A
470
Europe, RoW
Left ventricular septal pacing, Right ventricular pacing
Maastricht University, ZonMw: The Netherlands Organisation for Health Research and Development, Medtronic
Cardiac Pacing, Pacing-Induced Cardiomyopathy, Conduction System Pacing, Left Ventricular Septal Pacing, Atrioventricular Block
05/25
05/25
Gorp, Toon Van
ENGOT-EN20, NCT05611931 / 2022-002540-42: Selinexor in Maintenance Therapy After Systemic Therapy for Participants with P53 Wild-Type, Advanced or Recurrent Endometrial Carcinoma

Jul 2024 - Dec 2024: Top-line data from XPORT-EC trial in participants with TP53 wild type endometrial cancer
Recruiting
3
220
Europe, Canada, US, RoW
Selinexor, KPT-330, Matching Placebo for selinexor
Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group
Endometrial Cancer
01/25
01/28
PICCOLO, NCT05041257: Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers

Hourglass Oct 2024 - Dec 2024 : Approval for 2L+ FRα +ve PROC
Hourglass Jan 2024 - Jun 2024 : FDA action date for approval for ovarian cancer with high FRAC
Hourglass Jan 2024 - Jun 2024 : sBLA approval for ovarian cancer
Hourglass Jan 2023 - Dec 2023 : ORR data from PICCOLO trial for platinum sensitive ovarian cancer
Completed
2
79
Europe, Canada, US, RoW
Mirvetuximab soravtansine, MIRV, IMGN853
AbbVie
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
01/24
12/24
NCT05456685: Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer

Checkmark Data from trial in combination with carboplatin for platinum-sensitive epithelial ovarian cancer at IGCS 2022
Sep 2022 - Oct 2022: Data from trial in combination with carboplatin for platinum-sensitive epithelial ovarian cancer at IGCS 2022
Active, not recruiting
2
125
Europe, Canada, US, RoW
Mirvetuximab soravtansine, MIRV, IGN853, Carboplatin
AbbVie
High Grade Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer
05/26
05/26
ENGOT-ov60, NCT04625270 / 2020-004264-26: A Study of Avutometinib (VS-6766) V. Avutometinib (VS-6766) + Defactinib in Recurrent Low-Grade Serous Ovarian Cancer with and Without a KRAS Mutation

Active, not recruiting
2
225
Europe, Canada, US
avutometinib (VS-6766), avutometinib (VS-6766) and defactinib, avutometinib (VS-6766) and VS-6063
Verastem, Inc., European Network of Gynaecological Oncological Trial Groups (ENGOT), GOG Foundation
Low Grade Ovarian Serous Adenocarcinoma, Ovarian Cancer
11/24
12/26
TEDOVA, NCT04713514 / 2020-004364-25: OSE2101 Alone or in Combination With Pembrolizumab vs BSC in Patient With Platinum-sensitive Recurrent OC

Active, not recruiting
2
180
Europe
OSE2101, TEDOPI®, Pembrolizumab 25 MG/ML [Keytruda], KEYTRUDA®, MK-3475
ARCAGY/ GINECO GROUP, OSE Immunotherapeutics, Merck Sharp & Dohme LLC
Platinum-sensitive Ovarian Cancer, Relapsed Ovarian Cancer
12/25
12/25
NCT06431594: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors

Recruiting
1
240
Europe, Canada, Japan, US, RoW
GSK5733584
GlaxoSmithKline
Solid Tumors, Neoplasms
10/26
06/27
Biffi, Mauro
NCT05356546: TYRX™ Pocket Health Study

Completed
N/A
36
Europe, Canada, US
Study-required procedures include: tissue collection from device capsule, questionnaire collection, and photo collection
Medtronic Cardiac Rhythm and Heart Failure
Cardiac Disease, Healing Surgical Wounds
07/23
07/23
NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry

Recruiting
N/A
1000
Europe, Canada, US, RoW
Defibrillation using EV-ICD
Medtronic
Ventricular Arrhythmia, Tachycardia
05/30
10/37
Emans, PJ
AIR2, NCT05297175: AIR (Artificial Implant to Restore the Medial Meniscus Function)2 Clinical Investigation

Recruiting
N/A
10
Europe
Trammpolin medial meniscus prosthesis
ATRO Medical B.V., Avania
Knee Injuries and Disorders
09/24
12/24

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