| Schouten, Harry |
NCT00603330: Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft Function |
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| Recruiting | 2 | 100 | Europe | Mesenchymal stem cells | University of Liege, KU Leuven, Maastricht University Medical Center, Ziekenhuis Netwerk Antwerpen (ZNA), University Hospital, Antwerp, University Hospital, Ghent, AZ-VUB, AZ Sint-Jan AV, Cliniques universitaires Saint-Luc- Université Catholique de Louvain, University Hospital of Mont-Godinne, Jolimont Hospital Haine Saint Paul, Queen Fabiola Children's University Hospital | Graft-versus-host Disease, Poor Graft Function, Low Donor T-cell Chimerism | 08/24 | 08/24 | | |
| Theunissen, Koen |
NCT00603330: Mesenchymal Stem Cell Infusion as Treatment for Steroid-Resistant Acute Graft Versus Host Disease (GVHD) or Poor Graft Function |
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| Recruiting | 2 | 100 | Europe | Mesenchymal stem cells | University of Liege, KU Leuven, Maastricht University Medical Center, Ziekenhuis Netwerk Antwerpen (ZNA), University Hospital, Antwerp, University Hospital, Ghent, AZ-VUB, AZ Sint-Jan AV, Cliniques universitaires Saint-Luc- Université Catholique de Louvain, University Hospital of Mont-Godinne, Jolimont Hospital Haine Saint Paul, Queen Fabiola Children's University Hospital | Graft-versus-host Disease, Poor Graft Function, Low Donor T-cell Chimerism | 08/24 | 08/24 | | |
| Recruiting | N/A | 100 | Europe | Teclistamab, Tecvayli | Universitaire Ziekenhuizen KU Leuven, Janssen Pharmaceutica | Multiple Myeloma, Hematologic Diseases | 09/27 | 09/27 | | |
| Poeze, Martijn |
| Recruiting | N/A | 115 | Europe | Permissive Weight Bearing group, Early Weight Bearing, Restricted Weight Bearing group, Non Weight Bearing | Maastricht University Medical Center | Calcaneus Fracture, Displaced Intra-Articular Fracture of Calcaneus (Diagnosis), Trauma Injury | 07/25 | 01/26 | | |
NCT04112992: An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects |
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| Recruiting | N/A | 600 | Europe, US, RoW | Any treatment that is used for a defect of any long bone | AO Innovation Translation Center | Limb Fracture, Bone Loss | 05/28 | 03/29 | | |
| koeveringe, Gommert van |
| Active, not recruiting | N/A | 180 | Europe, RoW | Questionnaires on Urinary Incontinence-, Sex Function- and Quality of Life (ICIQ-UI-SF, ICIQ-FLUTSsex, ICIQ-LUTSqol, PGI-I) | European Association of Urology Research Foundation, Boston Scientific Corporation | Urinary Incontinence, Urinary Incontinence, Stress, Lower Urinary Tract Symptoms, Urination Disorders, Urologic Diseases | 06/25 | 12/26 | | |
| Heymans, Stephane |
| Recruiting | N/A | 1600 | Europe | | Institut National de la Santé Et de la Recherche Médicale, France | Cardiomyopathy, Diabetic | 10/27 | 10/27 | | |
| Nuijts, Rudy MMA |
| Active, not recruiting | N/A | 94 | Europe | remote monitoring after cataract surgery | UMC Utrecht, Health Holland | Cataract | 05/23 | 07/23 | | |
| Completed | N/A | 32 | Europe | Acunex Vario intraocular lens, Alcon AcrySof IQ Vivity intraocular lens | Maastricht University Medical Center | Cataract Bilateral, Lens, Intraocular, Lens Implantation, Intraocular, Pseudophakia, Visual Acuity | 06/23 | 06/23 | | |
| Recruiting | N/A | 140 | Europe, RoW | Artiflex Presbyopic implantation | Ophtec BV | Presbyopia, Ametropia, Refractive Errors, Myopia, Hyperopia | 07/23 | 07/25 | | |
| Greve, Jan Willem M |
| Not yet recruiting | 4 | 152 | NA | Placebo, Semaglutide 2.4 MG/0.75 ML Subcutaneous Solution [WEGOVY], Wegovy, Semaglutide | Zuyderland Medisch Centrum, Nederlandse Obestias Kliniek (NOK) | Obesity, Obesity, Morbid, Weight Gain | 02/26 | 09/26 | | |
NCT04902625: Use of Mysimba in Patients With Weight Regain After Bariatric Surgery |
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| Recruiting | 4 | 116 | Europe | Naltrexone-Bupropion Combination, Mysimba, Contrave | Zuyderland Medisch Centrum, Nederlandse Obesitas Kliniek | Obesity, Morbid, Bariatric Surgery Candidate, Medication Persistence | 03/25 | 03/25 | | |
| Jobe, Blair A |
NCT05591053: Utility and Usability of ActivSight™ Laser Speckle Imaging in Visualization of Tissue Perfusion and Blood Flow During Esophageal Surgery in Humans |
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| Recruiting | N/A | 70 | US | ActivSight | Activ Surgical, University of Pittsburgh Medical Center, West Penn Allegheny Health System | Esophagus Cancer, Esophageal Cancer, Esophageal Neoplasms, Esophageal Diseases, Esophageal Adenocarcinoma, Esophageal Squamous Cell Carcinoma, Esophagus SCC, Esophagus Tumor, Esophagus Adenocarcinoma, Esophagus Neoplasm | 01/25 | 01/25 | | |
NCT04695171: LINX Reflux Management System or Fundoplication Clinical Study in Patients With Hiatal Hernia >3 cm |
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| Recruiting | N/A | 450 | US | LINX Reflux Management System, Magnetic Augmentation System, Magnetic Sphincter Augmentation Device, MSAD, Magnetic Sphincter Augmentation, MSA, Fundoplication, Nissen fundoplication, Partial fundoplication, Toupet fundoplication, Watson fundoplication, Dor fundoplication | Foregut Research Foundation | Hiatal Hernia Large, Gastro Esophageal Reflux, Hiatal Hernia, Hiatal Hernia, Paraesophageal, Reflux, Gastroesophageal, Reflux Acid | 01/27 | 01/28 | | |
| Bouvy, Nicole D |
| Active, not recruiting | N/A | 650 | Europe | Pain tracking app | Radboud University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development | Adhesions Abdominal, Adhesions Pelvic, Surgery Induced Tissue Adhesions, Chronic Pain | 07/24 | 07/25 | | |
PROMISS, NCT03750942: PROphylactic Mesh to Prevent Incisional Hernias at the Former Stoma Site: the -trial |
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| Not yet recruiting | N/A | 130 | Europe | Adhesix® monofilament polypropylene mesh (Bard Davol) | Maastricht University Medical Center | Incisional Hernia | 03/23 | 03/23 | | |
MARS, NCT05424484: Mesh Augmented Reinforcement of Abdominal Wall Suture Line to Limit the Rate of Incisional Hernia Occurrence |
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| Recruiting | N/A | 120 | Europe, RoW | Self-Gripping Resorbable Mesh | Medtronic - MITG | Incisional Hernia, Incisional Hernia of Midline of Abdomen, Midline Laparotomy | 05/25 | 09/28 | | |
NCT04883294: Validation of the Diagnostic Accuracy of the Electronic Nose in the Detection of Thyroid Cancer |
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| Not yet recruiting | N/A | 1500 | NA | Electronic Nose, AeonoseTM | Maastricht University Medical Center | Thyroid Neoplasm | 01/24 | 01/25 | | |
| Beets, Geerard L |
NCT03426397: "Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer |
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| Recruiting | N/A | 220 | Europe | | The Netherlands Cancer Institute, Dutch Cancer Society | Rectal Neoplasms | 06/21 | 06/26 | | |
| Everdingen, Marieke HJ van den Beuken-van |
NCT05506137: Xerostomia in Patients With a Life-limiting Condition or Frailty |
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| Not yet recruiting | 3 | 120 | NA | Pilocarpine, Placebo | Maastricht University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development | Xerostomia, Dry Mouth | 02/25 | 06/25 | | |
| Vernooy, Kevin |
| Recruiting | N/A | 130 | Europe | CARTBox | UMC Utrecht, CART-Tech B.V., ZonMw: The Netherlands Organisation for Health Research and Development, Health Holland | Heart Failure | 04/23 | 02/25 | | |
ISOLATION, NCT04342312: Intensive Molecular and Electropathological Characterization of Patients Undergoing Atrial Fibrillation Ablation |
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| Recruiting | N/A | 500 | Europe | Pulmonary vein isolation, atrial fibrillation ablation, AF ablation | Maastricht University, Maastricht University Medical Center, Radboud University | Atrial Fibrillation, Atrial Fibrillation Paroxysmal, Atrial Fibrillation, Persistent | 05/23 | 05/24 | | |
NCT04863664: Lead EvaluAtion for Defibrillation and Reliability (LEADR) / Lead Evaluation for Defibrillation and Reliability in Left Bundle Branch Area Pacing (LEADR LBBAP) |
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| Recruiting | N/A | 975 | Europe, Canada, Japan, US, RoW | Defibrillation (RV Implant), Defibrillation (LBBAP Implant) | Medtronic Cardiac Rhythm and Heart Failure | Tachyarrhythmia | 06/25 | 02/26 | | |
CRT-DRIVE, NCT05327062: Cardiac Resynchronization Therapy Delivery Guided Non-Invasive Electrical and Venous Anatomy Assessment |
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| Recruiting | N/A | 150 | Europe, US | CRT implantation guided by XSpline, a non-invasive electrical and venous anatomy assessment | XSpline S.p.A. | Cardiac Resynchronization Therapy, Chronic Heart Failure, Left Bundle-Branch Block | 03/25 | 09/25 | | |
RACE-8-HF, NCT04342832: Cryoballoon Ablation Versus Medical Therapy in Patients With Heart Failure and Atrial Fibrillation |
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| Recruiting | N/A | 600 | Europe | Cryoballoon ablation, Pulmonary vein isolation, PVI, CBA | Maastricht University | Atrial Fibrillation, Heart Failure, Heart Failure With Reduced Ejection Fraction, Heart Failure, Systolic | 09/24 | 09/24 | | |
ABACUS, NCT06207383: Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation with Conduction System Pacing in Heart Failure |
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| Recruiting | N/A | 220 | Europe | Conduction system pacing, Atrioventricular nodal ablation, Atrial fibrillation ablation | University Hospital, Geneva, Swiss National Science Foundation | Atrial Fibrillation, Persistent, Heart Failure | 06/28 | 12/28 | | |
NCT06324188: Early Atrial Fibrillation Ablation for Stroke Prevention in Patients with High Comorbidity Burden (EASThigh-AFNET 11) |
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| Recruiting | N/A | 2312 | Europe, Canada, RoW | Early atrial fibrillation ablation, Usual Care | Atrial Fibrillation Network | Atrial Fibrillation | 02/30 | 05/30 | | |
NCT04831125: Conduction System Pacing International Registry (CONSPIRE) |
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| Recruiting | N/A | 1000 | Europe, US | Data collection | University of Chicago, Biotronik SE & Co. KG | Bradyarrhythmia, Heart Failure | 04/25 | 04/25 | | |
| Recruiting | N/A | 470 | Europe, RoW | Left ventricular septal pacing, Right ventricular pacing | Maastricht University, ZonMw: The Netherlands Organisation for Health Research and Development, Medtronic | Cardiac Pacing, Pacing-Induced Cardiomyopathy, Conduction System Pacing, Left Ventricular Septal Pacing, Atrioventricular Block | 05/25 | 05/25 | | |
| Not yet recruiting | N/A | 1500 | NA | | Maastricht University Medical Center, Maastricht University | Atrial Fibrillation | 08/28 | 08/28 | | |
| Breukink, Stephanie O |
NCT03426397: "Wait-and-see" Policy for Complete Responders After Chemoradiotherapy for Rectal Cancer |
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| Recruiting | N/A | 220 | Europe | | The Netherlands Cancer Institute, Dutch Cancer Society | Rectal Neoplasms | 06/21 | 06/26 | | |
NCT04101773: Napoleon Trial: Optimal Treatment for Recurrent Haemorrhoidal Disease |
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| Not yet recruiting | N/A | 558 | Europe | RBL versus sutured mucopexy versus haemorrhoidectomy. | Maastricht University Medical Center, ZonMw: The Netherlands Organisation for Health Research and Development | Hemorrhoids | 03/23 | 03/23 | | |
| Gorp, Toon Van |
| Recruiting | 3 | 220 | Europe, Canada, US, RoW | Selinexor, KPT-330, Matching Placebo for selinexor | Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group | Endometrial Cancer | 01/25 | 01/28 | | |
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PICCOLO, NCT05041257: Mirvetuximab Soravtansine Monotherapy in Platinum-Sensitive Epithelial, Peritoneal, and Fallopian Tube Cancers |
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| Completed | 2 | 79 | Europe, Canada, US, RoW | Mirvetuximab soravtansine, MIRV, IMGN853 | AbbVie | Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer | 01/24 | 12/24 | | |
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NCT05456685: Mirvetuximab Soravtansine (MIRV) With Carboplatin in Second-line Treatment of Folate Receptor Alpha (FRα) Expressing, Platinum-sensitive Epithelial Ovarian Cancer |
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| Active, not recruiting | 2 | 125 | Europe, Canada, US, RoW | Mirvetuximab soravtansine, MIRV, IGN853, Carboplatin | AbbVie | High Grade Ovarian Cancer, Primary Peritoneal Cancer, Fallopian Tube Cancer | 05/26 | 05/26 | | |
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| Active, not recruiting | 2 | 225 | Europe, Canada, US | avutometinib (VS-6766), avutometinib (VS-6766) and defactinib, avutometinib (VS-6766) and VS-6063 | Verastem, Inc., European Network of Gynaecological Oncological Trial Groups (ENGOT), GOG Foundation | Low Grade Ovarian Serous Adenocarcinoma, Ovarian Cancer | 11/24 | 12/26 | | |
| Active, not recruiting | 2 | 180 | Europe | OSE2101, TEDOPI®, Pembrolizumab 25 MG/ML [Keytruda], KEYTRUDA®, MK-3475 | ARCAGY/ GINECO GROUP, OSE Immunotherapeutics, Merck Sharp & Dohme LLC | Platinum-sensitive Ovarian Cancer, Relapsed Ovarian Cancer | 12/25 | 12/25 | | |
NCT06431594: A Study to Evaluate the Safety, Tolerability, Pharmacokinetics and Clinical Activity of GSK5733584 for Injection in Participants With Advanced Solid Tumors |
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| Recruiting | 1 | 240 | Europe, Canada, Japan, US, RoW | GSK5733584 | GlaxoSmithKline | Solid Tumors, Neoplasms | 10/26 | 06/27 | | |
| Kooi, M E |
| Active, not recruiting | 3 | 10 | Europe | 18F-choline PET-CT imaging, 18F-fluormethylcholine, [F18] choline, [F18] fluormethylcholine | Maastricht University Medical Center, Center for Translational Molecular Medicine | Plaque, Atherosclerotic | 12/15 | 12/15 | | |
| Recruiting | 3 | 14 | Europe | 18F-choline PET-MR imaging, PET-MRI | Maastricht University Medical Center | Plaque, Atherosclerotic | 03/24 | 03/24 | | |
| Voo, S A |
| Active, not recruiting | 3 | 10 | Europe | 18F-choline PET-CT imaging, 18F-fluormethylcholine, [F18] choline, [F18] fluormethylcholine | Maastricht University Medical Center, Center for Translational Molecular Medicine | Plaque, Atherosclerotic | 12/15 | 12/15 | | |
| Biffi, Mauro |
| Recruiting | N/A | 640 | Europe | Conventional 3-lead CRT defibrillator system implantation, 2-lead CRT defibrillator system implantation | Associazione Portatori Dispositivi Impiantabili Cardiaci | Heart Failure, Cardiac Resynchronization Therapy | 04/25 | 04/25 | | |
| Recruiting | N/A | 500 | Europe | Subcutaneous Implantable Cardioverter Defibrillator | Luigi Sacco University Hospital | Sudden Cardiac Death, Cardiac Arrest, Ventricular Arrythmia, Implantable Cardiac Defibrillator | 12/22 | 12/22 | | |
TREEBEARD, NCT06324682: ConTempoRary Cardiac Stimulation in Clinical practicE: lEft, BivEntriculAr, Right, and conDuction System Pacing |
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| Recruiting | N/A | 8400 | Europe | Cardiac pacing - Conventional RV pacing, Cardiac defibrillation - Conventional RV pacing, Cardiac pacing - Conduction System Pacing, Cardiac defibrillation - Conduction System Pacing, Cardiac pacing - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD), Cardiac defibrillation - Cardiac resynchronization therapy (pacing - CRTP - or defibrillation - CRTD), Cardiac pacing - Epicardial pacing, Cardiac defibrillation - Epicardial pacing, Cardiac pacing - Leadless pacing, Cardiac defibrillation - Leadless pacing | University Hospital of Ferrara | Arrhythmias, Cardiac, Atrioventricular Block, Reduced Systolic Function, Atrial Fibrillation, Bradyarrhythmia, Ventricular Tachycardia, Ventricular Dysfunction, Ventricular Fibrillation, Ventricular Arrythmia, Atrioventricular Nodal Disease, Atrioventricular Conduction Defects, Atrioventricular Block Complete, Atrioventricular Block Incomplete, Atrioventricular Junctional Rhythm, Bundle-Branch Block, Left Bundle-Branch Block, Heart Failure, Systolic, Block;Atrioventricular, Block; Arrhythmic, Block; Mobitz, Block, Heart, Block, Fascicular, Block Branch Bundle Left, Heart Failure，Congestive, Heart Arrhythmia | 12/33 | 12/34 | | |
| Completed | N/A | 36 | Europe, Canada, US | Study-required procedures include: tissue collection from device capsule, questionnaire collection, and photo collection | Medtronic Cardiac Rhythm and Heart Failure | Cardiac Disease, Healing Surgical Wounds | 07/23 | 07/23 | | |
ABACUS, NCT06207383: Atrial Fibrillation Ablation Versus Atrioventricular Nodal Ablation with Conduction System Pacing in Heart Failure |
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| Recruiting | N/A | 220 | Europe | Conduction system pacing, Atrioventricular nodal ablation, Atrial fibrillation ablation | University Hospital, Geneva, Swiss National Science Foundation | Atrial Fibrillation, Persistent, Heart Failure | 06/28 | 12/28 | | |
| Recruiting | N/A | 2000 | Europe | Leadless Pacemaker (Micra) | Luigi Sacco University Hospital, Università degli Studi di Brescia, Centro Cardiologico Monzino, University Hospital, Zürich, Azienda Ospedaliera Cardinale G. Panico, Azienda Ospedaliera San Gerardo di Monza, IRCCS Azienda Ospedaliero-Universitaria di Bologna, San Raffaele University Hospital, Italy, Ospedale V. Fazzi, Ospedali Riuniti Ancona, Universitair Ziekenhuis Brussel, Università degli Studi di Ferrara, University of Padova | Block Complete Heart, Atrial Fibrillation | 12/24 | 12/24 | | |
NCT06048731: Enlighten Study: The EV-ICD Post Approval Registry |
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| Recruiting | N/A | 1000 | Europe, Canada, US, RoW | Defibrillation using EV-ICD | Medtronic | Ventricular Arrhythmia, Tachycardia | 05/30 | 10/37 | | |
| Faber, Karin G |
| Completed | 1 | 6 | Europe | autologous mesoangioblasts | Maastricht University | Mitochondrial Myopathies | 09/22 | 12/22 | | |
| Emans, PJ |
AIR2, NCT05297175: AIR (Artificial Implant to Restore the Medial Meniscus Function)2 Clinical Investigation |
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| Recruiting | N/A | 10 | Europe | Trammpolin medial meniscus prosthesis | ATRO Medical B.V., Avania | Knee Injuries and Disorders | 09/24 | 12/24 | | |
