University of Iowa Health Care
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 43 Trials 
120 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Haas, David
NCT04636437: Doravirine for Persons With Excessive Weight Gain on Integrase Inhibitors and Tenofovir Alafenamide

Active, not recruiting
4
222
US
Doravirine 100 Mg, Tenofovir alafenamide/emtricitabine, tenofovir alafenamide/lamivudine, Integrase strand transfer inhibitors, tenofovir disproxil fumarate/emtricitabine, tenofovir disproxil fumarate/lamivudine
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
11/24
11/24
STOMP, NCT05534984: Study of Tecovirimat for Human Mpox Virus

Active, not recruiting
3
719
Japan, US, RoW
Tecovirimat Oral Capsule, Placebo, Tecovirimat Oral Capsule (Open Label)
National Institute of Allergy and Infectious Diseases (NIAID), SIGA Technologies
MPOX
10/24
09/25
NCT05033743: Suppressive Antibacterial Therapy With Once-Weekly Secnidazole Granules to Prevent Recurrent Bacterial Vaginosis; A Pilot Study

Completed
2/3
24
US
Secnidazole 2 GM Oral Granules
Indiana University, Lupin Pharmaceuticals, Inc.
Recurrent Bacterial Vaginosis
10/22
10/22
NCT05630885: A Study to Evaluate the Effects of Cenicriviroc Mesylate on Arterial Inflammation in People Living With HIV

Completed
2
110
US
CVC 150 mg, CVC 300 mg, Placebo for CVC 150 mg, Placebo for CVC 300 mg
National Institute of Allergy and Infectious Diseases (NIAID), AbbVie
HIV-1-infection
06/24
06/24
MedMilk, NCT05099484: Medications in Breast Milk: A Convenience Pharmacokinetic Study

Completed
N/A
30
US
The MedMilk study
Indiana University
Pregnancy Related
09/22
09/22
NCT06445270: Evidence-informed Trial of Lifestyle Interventions to Improve Glycemic Parameters and Reduce Gestational Diabetes in High-risk Pregnant Individuals

Not yet recruiting
N/A
100
US
GDM Prevention Program
Indiana University, Northeastern University, University of Texas
Gestational Diabetes, Pregnancy Complications
04/29
12/30
NCT03696368: The Hoosier Moms Cohort

Completed
N/A
411
US
Indiana University
Pregnancy Related, Gestational Diabetes
01/23
01/23
NCT05492708: The Heartland Study

Recruiting
N/A
2600
US
Heartland Health Research Alliance, Indiana University School of Medicine
Pregnancy Related, Pregnancy Complications, Birth Defect, Gestational Age and Weight Conditions, Spontaneous Abortion, Miscarriage, Exposure to Herbicides
01/27
01/29
NCT00031408: Consent for Use of Stored Patient Specimens for Future Testing

Recruiting
N/A
30000
US
Advancing Clinical Therapeutics Globally for HIV/AIDS and Other Infections, National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infections
12/27
12/27
Hull, Andrew D
NCT01429389: Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

Recruiting
N/A
2000
Canada, US
Sequenom, Inc.
Down Syndrome, Fetal Aneuploidy
12/25
03/26
Tumlin, James A
MRA-ACE, NCT03502031: Safety and Efficacy of Two Year of RAAS Alone or in Combination With Spironolactone Therapy

Recruiting
4
72
US
Renin-Angiotensin (RAAS) alone, Lispril, Enalapril, Perindopril, Losarta, Valsar etc.,, Renin-Angiotensin (RAAS) blockers in combination with Spironolactone, Lisinopril, Enalapril, Perindopril, Losartan, Valsartan, or Spironolactone
James A. Tumlin, MD, Nelson Kopyt, MD
Renal Insufficiency, Chronic, Diabetic Nephropathy Type 2
10/22
10/24
ADAPT, NCT05535920: A Prospective, Randomized, Open-Label, Cross-Over Study of Lokelma to Control Interdialytic Hyperkalemia

Completed
4
88
US
LOKELMA 5 GM Powder for Oral Suspension
NephroNet, Inc., AstraZeneca
Hyperkalemia
04/24
04/24
FACT, NCT05546047: A Study of Acthar Gel Alone or With Tacrolimus to Reduce Proteinuria in Fibrillary Glomerulopathy Patients

Active, not recruiting
4
34
US
Acthar Gel 80 UNT/ML Injectable Solution, Tacrolimus 1.0 mg
NephroNet, Inc., Mallinckrodt
Fibrillary Glomerulonephritis
10/23
10/24
FALCON, NCT03918447 / 2018-004651-20: A Trial of Bardoxolone Methyl in Patients With ADPKD -

Terminated
3
667
Europe, Japan, US, RoW
Bardoxolone methyl oral capsule, RTA 402, Placebo oral capsule
Reata, a wholly owned subsidiary of Biogen, Reata Pharmaceuticals, Inc., REATA PHARMACEUTICALS, INC
Autosomal Dominant Polycystic Kidney, ADPKD
08/23
08/23
ALIGN, NCT04573478: Atrasentan in Patients With IgA Nephropathy

Active, not recruiting
3
404
Europe, Canada, Japan, US, RoW
Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo
Chinook Therapeutics, Inc.
IgA Nephropathy, Immunoglobulin A Nephropathy
12/26
12/26
DREAM-T2D, NCT04854512 / 2020-000763-23: Investigational Study of Delayed Release Metformin

Suspended
3
675
Europe, Canada, US, RoW
Metformin DR, ANJ900, MetDR, Metformin IR, Metformin DR Placebo, Metformin IR placebo
Anji Pharma
Diabetes Mellitus, Type 2
12/23
06/24
NCT03955445 / 2018-004253-24: Long-term Efficacy, Safety and Tolerability of Iptacopan in C3G or IC-MPGN

Recruiting
3
183
Europe, Canada, Japan, US, RoW
LNP023, iptacopan
Novartis Pharmaceuticals, Novartis Pharma AG
C3 Glomerulopathy, Idiopathic Immune-complex-membranoproliferative Glomerulonephritis
03/33
04/33
HUMAXX, NCT05908084: To Compare the Efficacy and Safety of the HAV With AVF in Female Patients With End-Stage Renal Disease Requiring Hemodialysis

Recruiting
3
150
US
HAV, AVF
Humacyte, Inc.
End Stage Renal Disease (ESRD)
10/26
10/27
APPEAR-C3G, NCT04817618 / 2020-004589-21: Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

Hourglass Jul 2024 - Dec 2024 : Submission for the adult C3G
Hourglass Jul 2024 - Dec 2024 : Submission in US for the adult C3G
Recruiting
3
98
Europe, Canada, Japan, US, RoW
Placebo, iptacopan, LNP023
Novartis Pharmaceuticals, Novartis Pharma AG
C3G
03/26
07/26
NCT06150924: Efficacy and Safety of Lorundrostat in Addition to Sodium-Glucose Cotransporter-2 Inhibitors (SGLT2i) in Subjects with Hypertension and Chronic Kidney Disease (CKD) with Albuminuria

Recruiting
2
60
US
Lorundrostat 25mg+SGLT2i QD, Washout, Placebo+SGLT2i QD, Placebo QD + SGLT2i QD, Washout, Lorundrostat 25mg+SGLT2i QD
Mineralys Therapeutics Inc.
Chronic Kidney Disease
02/25
05/25
BREAKOUT, NCT05709444: A Phase IIb, Multicenter, Open-Label, Prospective Study of Bremelanotide in Diabetic Kidney Disease

Completed
2
16
US
Bremelanotide, Bremelanotide acetate, RAAS inhibition therapy, Angiotensin-converting enzyme (ACE) inhibitors, Angiotensin II receptor blockers (ARBs)
Palatin Technologies, Inc
Kidney Disease
04/24
04/24
AFFINITY, NCT04573920: Atrasentan in Patients With Proteinuric Glomerular Diseases

Active, not recruiting
2
103
Europe, US, RoW
Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627
Novartis Pharmaceuticals
IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease, Diabetic Nephropathy Type 2, Immunoglobulin A Nephropathy
07/24
07/26
TRIDENT, NCT02986984: Transformative Research in Diabetic Nephropathy

Recruiting
N/A
400
US
There is no intervention, There are no interventions
University of Pennsylvania, MOUNT SINAI HOSPITAL, University of North Carolina, Northwestern University, University of New Mexico, Stanford University, The University of Texas Health Science Center at San Antonio, Ohio State University, Yale University, Albert Einstein College of Medicine, Oregon Health and Science University, Lehigh Valley Health Network, University of Arkansas, University of Southern California, University of Virginia, Regeneron Pharmaceuticals, Boehringer Ingelheim, GlaxoSmithKline, Gilead Sciences, Juvenile Diabetes Research Foundation, Novo Nordisk A/S
Diabetic Nephropathies, Diabetic Glomerulosclerosis
01/25
06/25
Lafayette, Richard
ALIGN, NCT04573478: Atrasentan in Patients With IgA Nephropathy

Active, not recruiting
3
404
Europe, Canada, Japan, US, RoW
Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo
Chinook Therapeutics, Inc.
IgA Nephropathy, Immunoglobulin A Nephropathy
12/26
12/26
AFFINITY, NCT04573920: Atrasentan in Patients With Proteinuric Glomerular Diseases

Active, not recruiting
2
103
Europe, US, RoW
Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627
Novartis Pharmaceuticals
IgA Nephropathy, Focal Segmental Glomerulosclerosis, Alport Syndrome, Diabetic Kidney Disease, Diabetic Nephropathy Type 2, Immunoglobulin A Nephropathy
07/24
07/26
REBOOT, NCT03949855: Belimumab With Rituximab for Primary Membranous Nephropathy

Recruiting
2
58
Canada, US
Belimumab, Benlysta®, Placebo for Belimumab, Belimumab placebo, Rituximab, Rituxan®
National Institute of Allergy and Infectious Diseases (NIAID), Immune Tolerance Network (ITN), GlaxoSmithKline, PPD DEVELOPMENT, LP, Rho Federal Systems Division, Inc.
Membranous Nephropathy, Nephrotic Syndrome
03/29
03/30
NCT06422923: A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

Recruiting
1/2
10
US
NRTX-1001, GABA-secreting interneurons
Neurona Therapeutics
Epilepsy, Temporal Lobe
07/26
07/40
MTLE, NCT05135091: FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

Recruiting
1/2
40
US
NRTX-1001, GABA-secreting interneurons, Sham Comparator
Neurona Therapeutics, California Institute for Regenerative Medicine (CIRM)
Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis
05/25
05/26
TRIDENT, NCT02986984: Transformative Research in Diabetic Nephropathy

Recruiting
N/A
400
US
There is no intervention, There are no interventions
University of Pennsylvania, MOUNT SINAI HOSPITAL, University of North Carolina, Northwestern University, University of New Mexico, Stanford University, The University of Texas Health Science Center at San Antonio, Ohio State University, Yale University, Albert Einstein College of Medicine, Oregon Health and Science University, Lehigh Valley Health Network, University of Arkansas, University of Southern California, University of Virginia, Regeneron Pharmaceuticals, Boehringer Ingelheim, GlaxoSmithKline, Gilead Sciences, Juvenile Diabetes Research Foundation, Novo Nordisk A/S
Diabetic Nephropathies, Diabetic Glomerulosclerosis
01/25
06/25
NEPTUNE, NCT01209000: Nephrotic Syndrome Study Network

Recruiting
N/A
1200
Canada, US
Kidney Biopsy
University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), The NephCure Foundation
Minimal Change Disease (MCD), Membranous Nephropathy, Glomerulosclerosis, Focal Segmental
06/26
06/26
McNamara, Patrick
IMGN632-0802, NCT04086264: IMGN632 as Monotherapy or With Venetoclax and/or Azacitidine for Participants With CD123-Positive Acute Myeloid Leukemia

Active, not recruiting
1/2
218
Europe, US
Azacitidine, Vidaza, Decitabine, IMGN632, CD123-targeted ADC, Venetoclax, Venclexta, Venclyxto
AbbVie, Jazz Pharmaceuticals
Acute Myeloid Leukemia
04/26
04/26
NCT05314647: Lutein Supplementation in Healthy Children

Active, not recruiting
N/A
59
US
lutein, FloraGLO Lutein, placebo
Northcentral University
Eye Fatigue, Diet, Healthy, Cognitive Change
03/24
05/24
Bender, David P
NRG-GY019, NCT04095364: Letrozole With or Without Paclitaxel and Carboplatin in Treating Patients With Stage II-IV Ovarian, Fallopian Tube, or Primary Peritoneal Cancer

Recruiting
3
450
Europe, Canada, US, RoW
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Imaging Technique, Diagnostic Imaging Technique, Image Type, Imaging, Imaging (procedure), imaging procedure, Imaging Procedures, imaging type, IMAGING_METHOD, imaging_type, Medical Imaging, Type of imaging, Letrozole, CGS 20267, Femara, Fempro, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat
NRG Oncology, National Cancer Institute (NCI)
Low Grade Fallopian Tube Serous Adenocarcinoma, Ovarian Low Grade Serous Adenocarcinoma, Primary Peritoneal Low Grade Serous Adenocarcinoma, Stage II Fallopian Tube Cancer AJCC v8, Stage II Ovarian Cancer AJCC v8, Stage II Primary Peritoneal Cancer AJCC v8, Stage III Fallopian Tube Cancer AJCC v8, Stage III Ovarian Cancer AJCC v8, Stage III Primary Peritoneal Cancer AJCC v8, Stage IV Fallopian Tube Cancer AJCC v8, Stage IV Ovarian Cancer AJCC v8, Stage IV Primary Peritoneal Cancer AJCC v8
02/27
02/28
GLORIOSA, NCT05445778: Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer

Recruiting
3
418
Europe, Canada, US, RoW
Mirvetuximab soravtansine plus Bevacizumab, MIRV, Bevacizumab
AbbVie, GOG Foundation
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
03/27
04/29
NRG-GY026, NCT05256225: Testing the Addition of Trastuzumab or Trastuzumab/Pertuzumab to the Usual Chemotherapy for HER2 Positive Endometrial Cancer

Recruiting
2/3
525
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Echocardiography, EC, High-Dose-Rate Vaginal Cuff Brachytherapy, HDR-VCB, Hyaluronidase-zzxf/Pertuzumab/Trastuzumab, Pertuzumab and Trastuzumab hyaluronidase, Pertuzumab, Trastuzumab, and Hyaluronidase-zzxf, Pertuzumab/Trastuzumab/Hyaluronidase-zzxf, Phesgo, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, MUGA, Radionuclide Ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Quality-of-Life Assessment, Quality of Life Assessment, Trastuzumab/Hyaluronidase-oysk, Herceptin Hylecta, Trastuzumab and Hyaluronidase, Trastuzumab and Hyaluronidase-oysk, Trastuzumab and Recombinant Human Hyaluronidase PH20, Trastuzumab and rHuPH20, Trastuzumab-Hyaluronidase-oysk
National Cancer Institute (NCI), NRG Oncology
Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma, Endometrial Endometrioid Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Endometrial Undifferentiated Carcinoma, Uterine Corpus Carcinosarcoma
10/27
10/27
NRG-GY029, NCT05295589: Comparing Standard of Care Chemotherapy Treatment to the Combination of Copanlisib and Olaparib for Recurrent Platinum Resistant Ovarian Cancer That Has Progressed Through PARP Inhibitor Therapy

Withdrawn
2
96
US
Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, CT, CT Scan, tomography, Copanlisib Hydrochloride, 5-Pyrimidinecarboxamide, 2-Amino-N-(2,3-dihydro-7-methoxy-8-(3-(4-morpholinyl)propoxy)imidazo(1,2-C)quinazolin-5-yl)-, Hydrochloride (1:2), Aliqopa, BAY 80-6946 Dihydrochloride, BAY-80-6946 Dihydrochloride, Copanlisib Dihydrochloride, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, Olaparib, AZD 2281, AZD-2281, AZD2281, KU-0059436, Lynparza, PARP Inhibitor AZD2281, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Pegylated Liposomal Doxorubicin Hydrochloride, ATI-0918, Caelyx, Dox-SL, Doxil, Doxilen, Doxorubicin HCl Liposomal, Doxorubicin HCl Liposome, Doxorubicin Hydrochloride Liposome, Duomeisu, Evacet, LipoDox, Lipodox 50, Liposomal Adriamycin, Liposomal Doxorubicin Hydrochloride, Liposomal-Encapsulated Doxorubicin, Pegylated Doxorubicin HCl Liposome, S-Liposomal Doxorubicin, Stealth Liposomal Doxorubicin, TLC D-99, Topotecan Hydrochloride, Hycamptamine, Hycamtin, SKF S-104864-A, Topotecan HCl, topotecan hydrochloride (oral)
National Cancer Institute (NCI), NRG Oncology
Platinum-Refractory Fallopian Tube Carcinoma, Platinum-Refractory Ovarian Carcinoma, Platinum-Refractory Primary Peritoneal Carcinoma, Recurrent Fallopian Tube Endometrioid Adenocarcinoma, Recurrent Fallopian Tube High Grade Serous Adenocarcinoma, Recurrent Ovarian Endometrioid Adenocarcinoma, Recurrent Ovarian High Grade Serous Adenocarcinoma, Recurrent Platinum-Resistant Fallopian Tube Carcinoma, Recurrent Platinum-Resistant Ovarian Carcinoma, Recurrent Platinum-Resistant Primary Peritoneal Carcinoma, Recurrent Primary Peritoneal Endometrioid Adenocarcinoma, Recurrent Primary Peritoneal High Grade Serous Adenocarcinoma
03/23
03/23
NRG-GY033, NCT06169124: Study to Test the Drug Darolutamide Along With the Drugs Leuprolide Acetate and Exemestane in Patients With Recurrent Ovarian Granulosa Cell Tumors

Suspended
2
37
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Chest Radiography, Chest X-ray, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Darolutamide, Antiandrogen ODM-201, BAY 1841788, BAY-1841788, BAY1841788, Nubeqa, ODM 201, ODM-201, ODM201, Exemestane, Aromasin, FCE-24304, Leuprolide Acetate, A 43818, A-43818, A43818, Abbott 43818, Abbott-43818, Carcinil, Depo-Eligard, Eligard, Enanton, Enantone, Enantone-Gyn, Fensolvi, Ginecrin, LEUP, Leuplin, Leuprorelin Acetate, Lucrin, Lucrin Depot, Luprodex Depot, Lupron, Lupron Depot, Lupron Depot-3 Month, Lupron Depot-4 Month, Lupron Depot-Ped, Lutrate, Procren, Procrin, Prostap, TAP 144, TAP-144, TAP144, Trenantone, Uno-Enantone, Viadur, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT
National Cancer Institute (NCI), NRG Oncology
Adult Ovarian Granulosa Cell Tumor
05/27
05/27
NCI-2017-01672, NCT03660826: Testing the Combination of Olaparib and Durvalumab, Cediranib and Durvalumab, Olaparib and Capivasertib, and Cediranib Alone in Recurrent or Refractory Endometrial Cancer Following the Earlier Phase of the Study That Tested Olaparib and Cediranib in Comparison to Cediranib Alone, and Olaparib Alone

Active, not recruiting
2
286
Canada, US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspirate, BONE MARROW, LIQUID, Human Bone Marrow Aspirate, Bone Marrow Biopsy, Biopsy of Bone Marrow, Biopsy, Bone Marrow, Capivasertib, AZD 5363, AZD-5363, AZD5363, Truqap, Cediranib, AZ-D2171, AZD 2171, AZD2171, Cediranib Maleate, AZD2171 Maleate, Recentin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Durvalumab, Imfinzi, Immunoglobulin G1, Anti-(Human Protein B7-H1) (Human Monoclonal MEDI4736 Heavy Chain), Disulfide with Human Monoclonal MEDI4736 Kappa-chain, Dimer, MEDI 4736, MEDI-4736, MEDI4736, Echocardiography, EC, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNV Scan, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Olaparib, AZD 2281, AZD-2281, AZD2281, KU 0059436, KU-0059436, KU0059436, Lynparza, Olanib, Olaparix, PARP Inhibitor AZD2281
National Cancer Institute (NCI), NRG Oncology
Endometrial Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Serous Adenocarcinoma, Endometrial Undifferentiated Carcinoma, Endometrioid Adenocarcinoma, Stage IV Uterine Corpus Carcinoma or Carcinosarcoma AJCC v8
12/24
01/26
NRG-GY025, NCT05112601: Testing Nivolumab With or Without Ipilimumab in Deficient Mismatch Repair System (dMMR) Recurrent Endometrial Carcinoma

Recruiting
2
90
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Ipilimumab, Anti-Cytotoxic T-Lymphocyte-Associated Antigen-4 Monoclonal Antibody, BMS 734016, BMS-734016, BMS734016, Ipilimumab Biosimilar CS1002, MDX 010, MDX-010, MDX-CTLA4, MDX010, Yervoy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo
National Cancer Institute (NCI), NRG Oncology
Endometrial Adenocarcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Dedifferentiated Carcinoma, Endometrial Endometrioid Adenocarcinoma, Endometrial Mixed Cell Adenocarcinoma, Endometrial Mucinous Adenocarcinoma, Endometrial Undifferentiated Carcinoma, Endometrioid Adenocarcinoma, Recurrent Endometrial Carcinoma
04/26
04/26
VB-C-04, NCT06099418: Efficacy and Safety of VB10.16 Alone or in Combination With Atezolizumab in Patients With Advanced Cervical Cancer.

Withdrawn
2
130
NA
VB10.16, Atezolizumab Injection [Tecentriq], Placebo
Nykode Therapeutics ASA, Roche Pharma AG, GOG Foundation
HPV-Related Cervical Carcinoma, HPV-Related Malignancy, Cervical Cancer
05/27
05/28
NRG-GY028, NCT05538897: Testing the Addition of the AKT Inhibitor, Ipatasertib, to Treatment With the Hormonal Agent Megestrol Acetate for Recurrent or Metastatic Endometrial Cancers

Recruiting
1/2
96
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Ipatasertib, GDC 0068, GDC-0068, GDC0068, RG 7440, RG-7440, RG7440, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Megestrol Acetate, 17-Hydroxy-6-methylpregna-4,6-diene-3,20-dione acetate, 17.alpha.-Acetoxy-6-methylpregna-4,6-diene-3,20-dione, 6-Dehydro-6-methyl-17.alpha.-acetoxyprogesterone, 6-Methyl-6-dehydro-17.alpha.-acetoxyprogesterone, BDH 1298, BDH-1298, Maygace, Megace, Megestat, Megestil, Niagestin, Ovaban, Pallace, SC 10363, SC-10363
National Cancer Institute (NCI), NRG Oncology
FIGO Grade 1 Endometrial Endometrioid Adenocarcinoma, FIGO Grade 2 Endometrial Endometrioid Adenocarcinoma, Metastatic Endometrial Endometrioid Adenocarcinoma, Recurrent Endometrial Endometrioid Adenocarcinoma
01/27
01/27
NXP800-101, NCT05226507: A Phase 1 Clinical Study of NXP800 in Subjects with Advanced Cancers and Expansion in Subjects with Ovarian Cancer

Recruiting
1
61
Europe, US
NXP800
Nuvectis Pharma, Inc., European Network for Gynaecological Oncological Trial Groups, Gynecologic Oncology Group Foundation
Advanced Solid Tumor, Ovarian Cancer, Ovarian Clear Cell Carcinoma, Ovarian Clear Cell Tumor, Ovarian Clear Cell Adenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian Endometrioid Tumor, ARID1A Gene Mutation
05/25
12/25
NRG-GY031, NCT05950464: Testing Different Amounts of the Combination of Drugs M1774 and ZEN-3694 for the Treatment of Recurrent Ovarian and Endometrial Cancer

Recruiting
1
60
US
BET Bromodomain Inhibitor ZEN-3694, BETi ZEN-3694, ZEN 3694, ZEN-3694, ZEN003694, Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Electrocardiography, ECG, EKG, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Tuvusertib, ATR Kinase Inhibitor M1774, M 1774, M-1774, M1774, X-Ray Imaging, Conventional X-Ray, Diagnostic Radiology, Medical Imaging, X-Ray, Plain film radiographs, Radiographic Imaging, Radiographic imaging procedure (procedure), Radiography, RG, Static X-Ray, X-Ray
National Cancer Institute (NCI), NRG Oncology
Endometrial Carcinoma, Endometrial Clear Cell Adenocarcinoma, Endometrial Endometrioid Adenocarcinoma, Endometrial Low Grade Endometrioid Adenocarcinoma, Ovarian Clear Cell Adenocarcinoma, Ovarian Endometrioid Adenocarcinoma, Ovarian High Grade Serous Adenocarcinoma, Ovarian Low Grade Endometrioid Adenocarcinoma, Platinum-Resistant Ovarian Carcinoma
04/26
04/26
SOROCk, NCT04251052: A Study to Compare Two Surgical Procedures in Individuals With BRCA1 Mutations to Assess Reduced Risk of Ovarian Cancer

Recruiting
N/A
2262
Canada, US, RoW
Bilateral Salpingectomy, Bilateral Salpingectomy with Oophorectomy, bilateral salpingo-oophorectomy, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Transvaginal Ultrasound, transvaginal sonography, TVS, TVU, Ultrasound Imaging, 2-Dimensional Grayscale Ultrasound Imaging, 2-Dimensional Ultrasound Imaging, 2D-US, Ultrasonography, Ultrasound, Ultrasound Test, Ultrasound, Medical, US
NRG Oncology, National Cancer Institute (NCI)
Ovarian Carcinoma
06/36
06/37
O'Dorisio, Thomas M
NCT03335670: Gallium 68 Pentixafor in Patients With Neuroendocrine Tumors

Active, not recruiting
1
30
US
[68Ga]Pentixafor, (68Ga)pentixafor
Yusuf Menda, National Cancer Institute (NCI), National Institutes of Health (NIH), Holden Comprehensive Cancer Center
Neuroendocrine Tumors
12/26
12/27
Truwit, Jonathon
NCT03808922 / 2018-004318-16: Phase III DAS181 Lower Tract PIV Infection in Immunocompromised Subjects (Substudy: DAS181 for COVID-19): RCT Study

Recruiting
3
274
Europe, US, RoW
DAS181, Placebo, DAS181 COVID-19, DAS181 OL
Ansun Biopharma, Inc.
Lower Respiratory Tract Infection, Parainfluenza, Immunocompromised, COVID-19
08/25
08/25
Schlegel, Nicole
NCT02122562: Ketamine Alcohol (in Treatment-Resistant Depression)

Recruiting
2
60
US
Ketamine
Mark Niciu, National Institute of Mental Health (NIMH)
Magnetic Resonance Imaging, Major Depression, Alcoholism
09/26
09/26
Sluka, Kathleen A
FM-TIPS, NCT04683042: Fibromyalgia TENS in Physical Therapy Study (TIPS): an Embedded Pragmatic Clinical Trial

Active, not recruiting
3
450
US
Transcutaneous Electrical Nerve Stimulation (TENS) with PT, PT only
Kathleen Sluka
Fibromyalgia
03/25
03/25
QUANTIFY, NCT06803056: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers

Not yet recruiting
N/A
120
US
Clinical exam, Ultrasound imaging, Magnetic Resonance Imaging
Ruth Chimenti, National Center for Complementary and Integrative Health (NCCIH), Rochester Institute of Technology
Plantar Fasciopathy, Achilles Tendinopathy, Controls
07/26
08/26
Holmes, James F
NCT03564795: Effectiveness of KeraStat Gel for Improved Cosmesis of Partial Thickness Burns

Terminated
N/A
14
US
KeraStat Gel, Silver Sulfadiazine, SSD
KeraNetics, LLC, Wake Forest University, United States Department of Defense
Partial-thickness Burn
03/23
03/23
STAT, NCT04368117: Standard Therapy Plus Active Therapy

Recruiting
N/A
166
US
Physical Therapy
American Burn Association, United States Department of Defense
Burn Injury, Physical Injury, Thermal Burn
08/25
09/25
ABRUPT2, NCT04356859: The Acute Burn ResUscitation Multicenter Prospective Trial

Recruiting
N/A
400
Canada, US
Albumin Human, albumin
American Burn Association, United States Department of Defense
Burn Injury
08/25
09/25
QUANTIFY, NCT06803056: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers

Not yet recruiting
N/A
120
US
Clinical exam, Ultrasound imaging, Magnetic Resonance Imaging
Ruth Chimenti, National Center for Complementary and Integrative Health (NCCIH), Rochester Institute of Technology
Plantar Fasciopathy, Achilles Tendinopathy, Controls
07/26
08/26
NCT05704062: Quantitative MRI Assessment of Breast Cancer Therapy Response

Recruiting
N/A
135
US
Diffusion Weighted Imaging, Diffusion Weighted MRI, Diffusion-Weighted Magnetic Resonance Imaging, Diffusion-Weighted MR Imaging, Diffusion-Weighted MRI, DW-MRI, DWI, DWI MRI, DWI-MRI, MR Diffusion-Weighted Imaging, Dynamic Contrast-Enhanced Magnetic Resonance Imaging, DCE, DCE MRI, DCE-MRI, DYNAMIC CONTRAST ENHANCED MRI
OHSU Knight Cancer Institute, National Cancer Institute (NCI), University of Washington, University of Iowa, Oregon Health and Science University
Breast Cancer
11/26
11/26
FAST, NCT05910567: A Research Study of Abdominal Ultrasound () in Children With Blunt Torso Trauma

Recruiting
N/A
4346
US
Focused Assessment with Sonography for Trauma (FAST) Examination, Abdominal Ultrasound, No Intervention: Standard of Care - Without the FAST Examination
James F. Holmes, MD, MPH, Pediatric Emergency Care Applied Research Network, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Blunt Trauma to Abdomen, Wounds and Injuries, Abdomen Injury, Abdominal Injury, Abdomen, Acute
04/27
04/27
Borowski, Kristi
NCT01429389: Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

Recruiting
N/A
2000
Canada, US
Sequenom, Inc.
Down Syndrome, Fetal Aneuploidy
12/25
03/26
Seering, Melinda
NCT05486416: Safety and Efficacy of HSK3486 Compared to Propofol for Induction of General Anesthesia in Adults With Elective Surgery

Completed
3
466
Europe, US
HSK3486, Propofol, Diprivan
Haisco-USA Pharmaceuticals, Inc.
General Anesthesia
07/24
07/24
NCT06559969: IV vs Epidural Opioids + Epidural Local Anesthetic for Laparotomy Analgesia

Recruiting
2/3
80
US
Intravenous administered opioid, hydromorphone IV, Epidural administered opioid, Hydromorphone epidural
University of Iowa
Laparotomy
05/25
08/25
NCT05868330: Comparison of Interscalene Catheter to Single Injection Interscalene Blocks for Total Shoulder Arthroplasties

Recruiting
N/A
56
US
Interscalene Catheter, Exparel Single Shot Interscalene Block
Melinda Seering
Post Operative Pain, Anesthesia, Nerve Block, Shoulder Osteoarthritis
10/24
01/25
Smith, Richard JH
NCT00200486: Molecular and Genomic Profiling of Head and Neck Tumors

Recruiting
N/A
1000
US
Montefiore Medical Center, National Institutes of Health (NIH), National Institute of Dental and Craniofacial Research (NIDCR)
Head and Neck Neoplasms
12/25
12/25
Feely, Shawna
INC-6603, NCT01203085: Development of Charcot Marie Tooth Disease (CMT) Pediatric Scale for Children With CMT

Recruiting
N/A
500
Europe, US, RoW
University of Iowa, National Institute of Neurological Disorders and Stroke (NINDS), Muscular Dystrophy Association, University of Rochester, Children's Hospital of Philadelphia, University College London Hospitals, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Sydney Children's Hospitals Network, Nemours Children's Clinic
Charcot Marie Tooth Disease
12/24
12/24
INC-6601, NCT01193075: Natural History Evaluation of Charcot Marie Tooth Disease (CMT) Types CMT1B, CMT2A, CMT4A, CMT4C, and Others

Recruiting
N/A
5000
Europe, Canada, US, RoW
Michael Shy, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Johns Hopkins University, National Institute of Neurological Disorders and Stroke (NINDS), King's College Hospital NHS Trust, Nemours Children's Hospital, Stanford University, University of Pennsylvania, University of Rochester, Children's Hospital of Philadelphia, Sydney Children's Hospitals Network, Rare Diseases Clinical Research Network, Muscular Dystrophy Association, National Institutes of Health (NIH), Charcot-Marie-Tooth Association, Massachusetts General Hospital, Cedars-Sinai Medical Center, University of Miami, University of Minnesota, Connecticut Children's Medical Center, University of Colorado, Denver, The National Hospital for Neurology and Neurosurgery, Dubowitz Neuromuscular Centre
Charcot Marie Tooth Disease
12/26
12/26
INC-6602, NCT01193088: Genetics of Charcot Marie Tooth (CMT) - Modifiers of CMT1A, New Causes of CMT2

Recruiting
N/A
1050
Europe, US, RoW
University of Iowa, National Institute of Neurological Disorders and Stroke (NINDS), Muscular Dystrophy Association, University of Rochester, University of Pennsylvania, King's College Hospital NHS Trust, Sydney Children's Hospitals Network, Children's Hospital of Philadelphia, University of Miami, Johns Hopkins University, Fondazione I.R.C.C.S. Istituto Neurologico Carlo Besta, Cedars-Sinai Medical Center, Nemours Children's Clinic, Stanford University, University of Minnesota, Massachusetts General Hospital, University of Colorado, Denver, Children's National Research Institute, University of Michigan, St. Jude Children's Research Hospital, Connecticut Children's Medical Center, Seattle Children's Hospital, The Hospital for Sick Children
Charcot-Marie-Tooth Disease, Type Ia (Disorder), HMSN
12/26
12/26
Paredes, Ana
OSOPOLAR, NCT04924868: Ursodeoxycolic Acid for the Prevention of Relapsing Complications After Gallstone Acute Pancreatitis

Not yet recruiting
3
332
Europe
Ursodeoxycholic Acid, Placebo
Hospital General Universitario de Alicante, Instituto de Salud Carlos III
Acute Pancreatitis Due to Gallstones
07/25
07/25
APPEAR-C3G, NCT04817618 / 2020-004589-21: Study of Efficacy and Safety of Iptacopan in Patients With C3 Glomerulopathy.

Hourglass Jul 2024 - Dec 2024 : Submission for the adult C3G
Hourglass Jul 2024 - Dec 2024 : Submission in US for the adult C3G
Recruiting
3
98
Europe, Canada, Japan, US, RoW
Placebo, iptacopan, LNP023
Novartis Pharmaceuticals, Novartis Pharma AG
C3G
03/26
07/26
PENINSULA, NCT06409741: PrEveNtion of Biliary Events After Acute Pancreatitis in NonSUrgicaL PAtients: Trial

Enrolling by invitation
N/A
126
Europe
Biliary sphincterotomy
Hospital General Universitario de Alicante, Hospital Universitario Ramon y Cajal, Hospital del Rio Hortega, Hospital Universitario Reina Sofia de Cordoba, Hospital Clínico Universitario de Valencia
Acute Pancreatitis Due to Gallstones, Acute Pancreatitis
07/27
07/27
Fleener, Diedre
NCT01429389: Specimen Collection from Pregnant Women At Increased Risk for Fetal Aneuploidy

Recruiting
N/A
2000
Canada, US
Sequenom, Inc.
Down Syndrome, Fetal Aneuploidy
12/25
03/26
Chimenti, Ruth L
QUANTIFY, NCT06803056: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers

Not yet recruiting
N/A
120
US
Clinical exam, Ultrasound imaging, Magnetic Resonance Imaging
Ruth Chimenti, National Center for Complementary and Integrative Health (NCCIH), Rochester Institute of Technology
Plantar Fasciopathy, Achilles Tendinopathy, Controls
07/26
08/26
PACE, NCT06736795: Progressive Achilles Loading Via Clinician E-support

Not yet recruiting
N/A
160
US
Exercise, Education
Ruth Chimenti, C.R.Darnall Army Medical Center, United States Department of Defense
Achilles Tendon Pain, Achilles Tendinopathy
06/28
07/28
Danielson, Jessica
QUANTIFY, NCT06803056: Quantitative Understanding of Advanced Novel Techniques for Imaging Fasciitis and Yielding Biomarkers

Not yet recruiting
N/A
120
US
Clinical exam, Ultrasound imaging, Magnetic Resonance Imaging
Ruth Chimenti, National Center for Complementary and Integrative Health (NCCIH), Rochester Institute of Technology
Plantar Fasciopathy, Achilles Tendinopathy, Controls
07/26
08/26
PACE, NCT06736795: Progressive Achilles Loading Via Clinician E-support

Not yet recruiting
N/A
160
US
Exercise, Education
Ruth Chimenti, C.R.Darnall Army Medical Center, United States Department of Defense
Achilles Tendon Pain, Achilles Tendinopathy
06/28
07/28
NCT03505476: Optimizing the Previs Device for Prediction of Postoperative Ileus

Recruiting
N/A
225
US
Entac Medical device application, Patient Daily Assessment, Patient Discharge Assessment
Jennifer Hrabe
Ileus
05/25
12/25
COSMID, NCT04095663: Comparison of Surgery and Medicine on the Impact of Diverticulitis () Trial

Recruiting
N/A
250
US
Partial Colectomy, Medical Management
University of Washington, Patient-Centered Outcomes Research Institute
Diverticulitis
10/26
11/26
Williams, Terry
MIRROR, NCT06074510: PYLARIFY® PET/CT or PET/MRI in Men with Favorable Intermediate Risk (FIR) Prostate Cancer

Recruiting
4
274
US
Piflufolastat F 18 Intravenous Solution [PYLARIFY], PYLARIFY, 18F-DCFPyL
Lantheus Medical Imaging
Prostate Cancer
11/26
11/26
VERACITY, NCT04844749: Efficacy Evaluation of VERU-111 for mCRPC in Patients Who Have Failed at Least One Androgen Receptor Targeting Agent

Terminated
3
105
US
VERU-111, Sabizabulin, Enzalutamide, Abiraterone, XTANDI, Zytiga
Veru Inc.
Metastatic Castration-resistant Prostate Cancer, Androgen Resistant Prostatic Cancer
05/23
05/23
NCT05156047: A Phase 3 Study to Assess the Safety and Efficacy of Pitolisant in Adult Patients With Idiopathic Hypersomnia

Completed
3
214
US
Open-label pitolisant, Double-blind placebo, Double-blind pitolisant
Harmony Biosciences, LLC
Idiopathic Hypersomnia
09/23
09/23
LEGEND study, NCT04752722: LEGEND Study: EG-70 in NMIBC Patients BCG-Unresponsive and High-Risk NMIBC Incompletely Treated With BCG or BCG-Naïve

Recruiting
1/2
222
Canada, US
EG-70 (phase 1), Phase 1, EG-70 (phase 2), Phase 2
enGene, Inc.
Superficial Bladder Cancer, Non-muscle Invasive Bladder Cancer With Carcinoma in Situ
06/25
05/27
Borus, Linda
GLORIOSA, NCT05445778: Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer

Recruiting
3
418
Europe, Canada, US, RoW
Mirvetuximab soravtansine plus Bevacizumab, MIRV, Bevacizumab
AbbVie, GOG Foundation
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
03/27
04/29
Niciu, Mark J
NCT02122562: Ketamine Alcohol (in Treatment-Resistant Depression)

Recruiting
2
60
US
Ketamine
Mark Niciu, National Institute of Mental Health (NIMH)
Magnetic Resonance Imaging, Major Depression, Alcoholism
09/26
09/26
NCT04480918: University of Iowa Interventional Psychiatry Service Patient Registry

Recruiting
N/A
1000
US
Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Ketamine, Esketamine, Deep Transcranial Magnetic Stimulation (dTMS)
Mark Niciu
Treatment Resistant Depression, Major Depressive Episode, Major Depression, Major Depressive Disorder, Bipolar Disorder, Bipolar Depression, Obsessive-Compulsive Disorder
08/50
08/50
Trapp, Nicholas T
NCT03378570: rTMS for MDD: 5.5cm Rule vs. F3 Targeting

Completed
N/A
123
US
Repetitive transcranial magnetic stimulation
Nicholas Trapp
Major Depressive Disorder, Depression
09/22
09/22
RAPID, NCT04441008: Accelerated iTBS for Depression and Suicidality

Not yet recruiting
N/A
50
NA
Accelerated Intermittent Theta Burst (aiTBS), SAINT Protocol, accelerated TMS, Electroconvulsive therapy (ECT)
University of Iowa
Major Depressive Disorder, Suicide
12/27
07/29
NCT04480918: University of Iowa Interventional Psychiatry Service Patient Registry

Recruiting
N/A
1000
US
Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Ketamine, Esketamine, Deep Transcranial Magnetic Stimulation (dTMS)
Mark Niciu
Treatment Resistant Depression, Major Depressive Episode, Major Depression, Major Depressive Disorder, Bipolar Disorder, Bipolar Depression, Obsessive-Compulsive Disorder
08/50
08/50
Pace, Benjamin
NCT06462820: SAINT for MDD in an Inpatient Setting Follow-on

Recruiting
2/3
100
US
Active SAINT Stimulation, Sham SAINT Stimulation
Magnus Medical
Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
12/25
02/26
NCT03693105: The Effects of SAINT® Neuromodulation System on Explicit and Implicit Suicidal Cognition

Recruiting
2/3
100
US
Active SAINT Stimulation, Sham SAINT Stimulation
Magnus Medical, National Institute of Mental Health (NIMH)
Major Depressive Disorder, Major Depressive Episode, Suicidal Ideation
12/25
02/26
NCT03378570: rTMS for MDD: 5.5cm Rule vs. F3 Targeting

Completed
N/A
123
US
Repetitive transcranial magnetic stimulation
Nicholas Trapp
Major Depressive Disorder, Depression
09/22
09/22
NCT04480918: University of Iowa Interventional Psychiatry Service Patient Registry

Recruiting
N/A
1000
US
Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Ketamine, Esketamine, Deep Transcranial Magnetic Stimulation (dTMS)
Mark Niciu
Treatment Resistant Depression, Major Depressive Episode, Major Depression, Major Depressive Disorder, Bipolar Disorder, Bipolar Depression, Obsessive-Compulsive Disorder
08/50
08/50
Neki, Poonam
NCT05481151: A Study to Assess Efficacy, Safety, and Tolerability of P1101 in Adult Patients With PV

Hourglass Feb 2024 - Dec 2024 : Topline data for adults with PV
Active, not recruiting
3
111
Canada, US
P1101 (Ropeginterferon alfa-2b-njft), Ropeginterferon alfa-2b-njft (P1101)
PharmaEssentia
Polycythemia Vera
12/24
07/25
GLORIOSA, NCT05445778: Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer

Recruiting
3
418
Europe, Canada, US, RoW
Mirvetuximab soravtansine plus Bevacizumab, MIRV, Bevacizumab
AbbVie, GOG Foundation
Ovarian Cancer, Peritoneal Cancer, Fallopian Tube Cancer
03/27
04/29
Mundisev, Amy
NCT06107374: Imaging Advanced NSCLC Patients Undergoing PD-1/PD-L1 Directed Therapy Using [18F]-FARAG

Recruiting
2
20
US
[18F]F-AraG
CellSight Technologies, Inc.
Advanced Non Small Cell Lung Cancer
12/25
03/26
NCT06084806: Test-retest Evaluation of [18F]F-AraG PET

Recruiting
2
10
US
[18F]F-ARAG PET
CellSight Technologies, Inc., University of Iowa
Non-small Cell Lung Cancer
10/25
10/25
NCT05759013: Pivotal Evaluation of Abdominal Neuromuscular Electrical Stimulation (VentFree) for Weaning from Mechanical Ventilation

Enrolling by invitation
N/A
272
Europe, US, RoW
Breath synchronized abdominal FES, VentFree Respiratory Muscle Stimulator, Sham breath synchronized abdominal FES
Liberate Medical, United States Department of Defense
Respiration, Artificial, Ventilators, Mechanical
12/25
03/26
Correia, Marcelo L
ACHIEVE-4, NCT05803421: A Study of Daily Oral Orforglipron (LY3502970) Compared With Insulin Glargine in Participants With Type 2 Diabetes and Obesity or Overweight at Increased Cardiovascular Risk

Active, not recruiting
3
2749
Europe, US, RoW
Orforglipron, LY3502970, Insulin Glargine
Eli Lilly and Company
Type 2 Diabetes, Obesity, Overweight or Obesity, Overweight, Cardiovascular Diseases, Chronic Kidney Disease
09/25
01/26
NCT04861571: Effect of VLCD on the Reduction of Liver Steatosis and Fibrosis in Subjects With Obesity and NAFLD

Recruiting
N/A
20
US
Dietary intervention with very low calorie diet (VLCD), VLCD Arm, Control Arm
University of Iowa
NAFLD
07/26
12/26
Buch, Vivek
NCT06422923: A Phase 1/2 Study of NRTX-1001 Neuronal Cell Therapy in Drug-Resistant Bilateral Mesial Temporal Lobe Epilepsy (MTLE)

Recruiting
1/2
10
US
NRTX-1001, GABA-secreting interneurons
Neurona Therapeutics
Epilepsy, Temporal Lobe
07/26
07/40
MTLE, NCT05135091: FIH Study of NRTX-1001 Neural Cell Therapy in Drug-Resistant Unilateral Mesial Temporal Lobe Epilepsy

Recruiting
1/2
40
US
NRTX-1001, GABA-secreting interneurons, Sham Comparator
Neurona Therapeutics, California Institute for Regenerative Medicine (CIRM)
Mesial Temporal Lobe Epilepsy With Hippocampal Sclerosis
05/25
05/26
NCT02844465: Stereotactic Laser Ablation for Temporal Lobe Epilepsy (Slate)

Completed
N/A
167
US
Visualase MRI-Guided Laser Ablation, Visualase System, Visualase procedure, Laser interstitial thermal therapy, Stereotactic laser ablation
MedtronicNeuro
Temporal Lobe Epilepsy
12/23
12/23
NCT06028477: Vibrotactile Coordinated Reset in Parkinson's Disease - Proof of Concept Study

Not yet recruiting
N/A
34
US
Stanford Glove
Stanford University
Parkinson Disease
12/26
03/27
NCT06052124: Augmented Reality for Subdural Drain Placement

Not yet recruiting
N/A
100
US
Augmented Reality Device
Stanford University
Subdural Hematoma
12/25
12/25
Badheka, Aditya
ECSTATIC, NCT05796557: ECMO Hemostatic Transfusions in Children

Active, not recruiting
4
50
US, RoW
Platelet Transfusion
Yale University, Weill Medical College of Cornell University, University of Utah, National Heart, Lung, and Blood Institute (NHLBI), Columbia University, Virginia Commonwealth University, University of Rochester, Children's Hospital and Health System Foundation, Wisconsin, Duke University, Johns Hopkins All Children's Hospital, University of Iowa, Emory University, Schneider Medical Children's Center, Israel
Extracorporeal Membrane Oxygenation Complication, Hemorrhage, Thromboembolism, Transfusion Adverse Reaction
01/25
03/25
 

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