| Baidal, David A |
DIAGNODE-3, NCT05018585 / 2021-002731-32: A Phase III Study to Investigate If the Study Drug Diamyd Can Preserve Insulin Production and Improve Glycemic Control in Patients Newly Diagnosed with Type 1 Diabetes |
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| Recruiting | 3 | 330 | Europe, US, RoW | Recombinant human glutamic acid decarboxylase (rhGAD65) formulated in Alhydrogel®, Diamyd, Colecalciferol 2000 IU, Divisun 2000 IU, Placebo | Diamyd Medical AB | Type 1 Diabetes Mellitus | 12/27 | 12/27 | | |
NCT05743244: Janus Kinase (JAK) Inhibitors to Preserve C-Peptide Production in New Onset Type 1 Diabetes (T1D) |
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| Recruiting | 2 | 78 | US | Abrocitinib 200 MG Oral Tablet, CIBINQO, Ritlecitinib, Placebo | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Pfizer | Diabetes Mellitus, Type 1 | 06/26 | 06/27 | | |
NCT03929601: Rituximab-pvvr and Abatacept Vs Rituximab-pvvr Alone in New Onset Type 1 Diabetes |
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| Recruiting | 2 | 74 | US, RoW | Rituximab-pvvr, Ruxience, Abatacept, Orencia, Sterile Sodium Chloride, 0.9% Sodium Chloride Water for Injection | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institutes of Health (NIH) | Type 1 Diabetes Mellitus | 10/27 | 10/29 | | |
| Active, not recruiting | 2 | 101 | US, RoW | Antithymocyte Globulin, Thymoglobulin, Placebo (for ATG) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Diabetes Mellitus, Type 1 | 12/28 | 12/29 | | |
| Completed | 1/2 | 25 | US | Cholecalciferol, Vitamin D, Omega 3 fatty acid, Omega 3 | Rodolfo Alejandro, Diabetes Research Institute Foundation | Diabetes Mellitus, Type 1, Hypoglycemia, Diabetes Mellitus, Diabetes, Autoimmune | 07/24 | 07/24 | | |
| Withdrawn | 1/2 | 45 | US | Anti-Thymocyte Globulin (ATG), Thymoglobulin, Interleukin 2, Aldesleukin; IL-2 or Proleukin®, Exenatide, Bydureon®, Adalimumab, HUMIRA®, ATG Placebo, IL-2 Placebo, Adalimumab Placebo, Exenatide Placebo | Camillo Ricordi and Jay Skyler, Diabetes Research Institute Foundation | Diabetes Mellitus, Type 1, Hypoglycemia, Autoimmune Diseases, Diabetes Mellitus | 12/28 | 12/29 | | |
NCT02846571: Pancreatic Islet Transplantation Into the Anterior Chamber of the Eye |
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| Recruiting | 1/2 | 2 | US | Human Pancreatic Islet Transplantation | Midhat H. Abdulreda, Diabetes Research Institute Foundation, Bascom Palmer Eye Institute | Diabetes | 12/26 | 12/27 | | |
| Active, not recruiting | 1/2 | 120 | US | Siplizumab, TCD 601 | National Institute of Allergy and Infectious Diseases (NIAID) | Type 1 Diabetes Mellitus | 12/26 | 12/27 | | |
NCT01999361: Prevention of de Novo Allosensitization in Islet Transplant Recipients Following Complete Graft Loss |
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| Recruiting | N/A | 18 | US | Myfortic, mycophenolic acid | Rodolfo Alejandro | Type 1 Diabetes Mellitus | 01/27 | 12/28 | | |
NCT01999374: Long Term Follow up of Recipients of Functional Islet Allografts |
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| Recruiting | N/A | 30 | US | | Rodolfo Alejandro | Type 1 Diabetes Mellitus | 03/27 | 12/28 | | |
NCT02000687: Long Term Surveillance of Islet Transplant Recipients Following Complete Graft Loss |
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| Recruiting | N/A | 60 | US | | Rodolfo Alejandro | Type 1 Diabetes Mellitus | 12/27 | 07/28 | | |
