University Health Network, Princess Margaret Cancer Center
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 14 Trials 
26 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Wong, Rebecca
NCT05661409: Sugammadex as Rescue Therapy

Completed
4
71
US
Sugammadex, Placebo
Emory University, National Center for Advancing Translational Sciences (NCATS), Georgia Clinical & Translational Science Alliance (CTSA)
Neuromuscular Blockade
08/24
08/24
NCT04084548: Perioperative Lidocaine and Ketamine in Abdominal Surgery

Active, not recruiting
3
420
US
Lidocaine and ketamine, Lidocaine, Ketamine, Placebo
The Cleveland Clinic
Postoperative Pain
12/24
12/24
TALES, NCT03011684: Fertility Preservation Using Tamoxifen and Letrozole in Estrogen Sensitive Tumors Trial

Recruiting
3
144
US
Tamoxifen, Letrozole
University of California, San Francisco
Infertility
01/25
01/25
NatPro, NCT04551807: Natural Versus Programmed Frozen Embryo Transfer

Active, not recruiting
3
788
US
Modified natural cycle, Programmed cycle
JHSPH Center for Clinical Trials
Pregnancy Related, Pre-Eclampsia
04/25
08/25
ACTION-1, NCT05477576 / 2022-000507-12: Study of RYZ101 Compared with SOC in Pts W Inoperable SSTR+ Well-differentiated GEP-NET That Has Progressed Following 177Lu-SSA Therapy

Recruiting
3
288
Europe, Canada, US, RoW
RYZ101, Everolimus, Sunitinib, Octreotide, Lanreotide
RayzeBio, Inc., RayzeBio, Inc.
GEP-NET, Gastroenteropancreatic Neuroendocrine Tumor, Gastroenteropancreatic Neuroendocrine Tumor Disease, Neuroendocrine Tumors, Carcinoid, Carcinoid Tumor, Pancreatic NET
12/25
07/28
NCT01761929: 5 Fraction Stereotactic Body Radiation Therapy for Oligometastases Regimen, for Extra-Cranial Oligometastases

Completed
2
138
Canada
Radiation: 50Gy in 5 fr (max) to 25 Gy in 5 fr (min). Dose adapted to deliver the highest dose level while respecting normal tissue tolerance
University Health Network, Toronto, Princess Margaret Hospital, Canada
Solid Tumors With Oligometastatic Spread
02/23
02/23
ASPIRE, NCT06588686: A Trial to Evaluate Efficacy and Safety of Buloxibutid in People With Idiopathic Pulmonary Fibrosis.

Recruiting
2
270
Europe, Canada, US, RoW
Buloxibutid, C21, Placebo
Vicore Pharma AB, Population Services International
Idiopathic Pulmonary Fibrosis (IPF)
02/27
03/27
NCT04467515: A Study to Evaluate Safety, Tolerability, Dosimetry, and Preliminary Efficacy of the HER2 Directed Radioligand CAM-H2 in Patients With Advanced/Metastatic HER2-Positive Breast, Gastric, and Gastro-Esophageal Junction (GEJ) Cancer

Terminated
1/2
13
Canada, US
CAM-H2
Precirix
Advanced/Metastatic HER2-positive Breast, Gastric, Gastroesophageal Junction Cancer With Disease Progression Following Anti-HER2 Standard of Care Treatment
12/23
12/23
NCT01428895: Femoral Bone Metastases

Recruiting
N/A
180
Canada
Surgery Alone, Combined Surgery and Radiation therapy
University Health Network, Toronto
Cancer, Metastatic Malignant Neoplasm to Femur, Risk of Fracture
02/25
02/25
S-C-PATHY, NCT06390657: Radiotherapy Treatment Planning Comparison Using SBRT-PATHY (Photons) Versus CARBON-PATHY for Unresectable Bulky Tumors

Not yet recruiting
N/A
20
Europe
Planning CT, MRI
EBG MedAustron GmbH, The Princess Margaret Cancer Foundation
Cancer
12/25
12/25
MDS & PRRT, NCT06510868: Evaluating Myelodysplastic Syndrome Risks in NET Patients Planned for Peptide Radionuclide Therapy

Not yet recruiting
N/A
45
Canada
Peptide receptor radionuclide therapy (PRRT), Blood collection
University Health Network, Toronto
Myelodysplastic Syndrome, Acute Myeloid Leukemia
04/28
06/29
NCT01279408: Observing Patients With Palliative Asymptomatic Centrally Located Advanced Non-small Cell Lung Carcinoma (NSCLC)

Active, not recruiting
N/A
46
Canada
None: Questionnaire Study
University Health Network, Toronto
Non-small Cell Lung Carcinoma
11/28
11/28
Kim, John
QWINT-1, NCT05662332: A Study of Insulin Efsitora Alfa (LY3209590) Compared to Glargine in Adult Participants With Type 2 Diabetes Who Are Starting Basal Insulin for the First Time

Completed
3
795
US, RoW
Insulin Efsitora Alfa, LY3209590 and Basal Insulin-FC, Insulin Glargine
Eli Lilly and Company
Type 2 Diabetes, T2D
07/24
07/24
ACHIEVE-1, NCT05971940: A Study of Orforglipron (LY3502970) in Adult Participants With Type 2 Diabetes and Inadequate Glycemic Control With Diet and Exercise Alone

Active, not recruiting
3
520
Japan, US, RoW
Orforglipron, LY3502970, Placebo
Eli Lilly and Company
Type 2 Diabetes
04/25
04/25
ACHIEVE-3, NCT06045221: A Study of Orforglipron (LY3502970) Compared With Semaglutide in Participants With Type 2 Diabetes Inadequately Controlled With Metformin

Active, not recruiting
3
1576
Japan, US, RoW
Orforglipron, LY3502970, Semaglutide
Eli Lilly and Company
Type 2 Diabetes
09/25
09/25
NRG-HN001, NCT02135042: Individualized Treatment in Treating Patients With Stage II-IVB Nasopharyngeal Cancer Based on EBV DNA

Active, not recruiting
2/3
685
Canada, US, RoW
Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Clinical Observation, Fluorouracil, 5-Fluoro-2,4(1H, 3H)-pyrimidinedione, 5-Fluorouracil, 5-Fluracil, 5-FU, AccuSite, Actino-Hermal, Adrucil, Arumel, Cytosafe, Efudex, Efurix, Fiverocil, Fluoro Uracil, Fluoroplex, Fluouracil, Flurablastin, Fluracedyl, Fluracil, Fluril, Fluroblastin, Flurox, Ribofluor, Ro 2-9757, Ro-2-9757, Timazin, Gemcitabine Hydrochloride, dFdCyd, Difluorodeoxycytidine Hydrochloride, Gemzar, LY-188011, Intensity-Modulated Radiation Therapy, IMRT, Intensity Modulated RT, Intensity-Modulated Radiotherapy, Laboratory Biomarker Analysis, Paclitaxel, Anzatax, Asotax, Bristaxol, Praxel, Taxol, Taxol Konzentrat, Quality-of-Life Assessment, Quality of Life Assessment
NRG Oncology, National Cancer Institute (NCI)
Epstein-Barr Virus Infection, Stage II Nasopharyngeal Carcinoma, Stage III Nasopharyngeal Carcinoma, Stage IVA Nasopharyngeal Carcinoma, Stage IVB Nasopharyngeal Carcinoma
02/26
02/31
NEPTUNE-17, NCT05838755: A Study to Evaluate Efficacy and Safety of GSK3858279 in Diabetic Peripheral Neuropathic Pain

Active, not recruiting
2
145
Europe, Canada, Japan, US, RoW
GSK3858279, Placebo
GlaxoSmithKline
Pain
10/24
01/25
NCT00937248: Cone Beam Computed Tomography (CT) (CBCT) With and Without a Customized Vacuum Immobilization Device (CVID)

Completed
N/A
20
Canada
prone pillow and simple ankle fixation device, Customized Vacuum Immobilization Device (CVID)
University Health Network, Toronto
Rectal Cancer
04/23
04/23
NCT03472768: The Impact of Age-dependent Haptoglobin Deficiency on Plasma Free Hemoglobin Levels During Extracorporeal Membrane Oxygenation Support

Active, not recruiting
N/A
90
US
Plasma Haptoglobin Concentration
University of Colorado, Denver
Respiratory Failure
09/24
09/24
NCT05763745: Bedside Ultrasonic Assessment for Gastric Content in Patients With Upper GI Bleeding Undergoing Endoscopy: a Pilot Study

Recruiting
N/A
50
US
Point of Care Ultrasound
Loma Linda University
Upper GI Bleeding, Point of Care Ultrasound, Upper Endoscopy, Gastric Content, GI Bleed
12/24
12/24
NCT06323876: The Role of Quantitative CT and Radiomic Biomarkers for Precision Medicine in Pulmonary Fibrosis

Recruiting
N/A
160
US
HRCT, Blood Draw
University of Virginia, National Heart, Lung, and Blood Institute (NHLBI)
Idiopathic Pulmonary Fibrosis
05/28
05/29
TITRE, NCT05405426: Trial of Indication-Based Transfusion of Red Blood Cells in ECMO

Recruiting
N/A
228
Canada, US, RoW
Red blood cell transfusion
Boston Children's Hospital
Extracorporeal Membrane Oxygenation, Red Blood Cell Transfusion, Organ Failure, Multiple
10/24
12/25
ACT-IPF, NCT03901534: Assessment of Continuous Positive Airway Pressure Therapy in OSA and ILD

Terminated
N/A
2021
US
Continuous positive airway pressure (CPAP) therapy, Nox A1 Recorder
Columbia University, National Heart, Lung, and Blood Institute (NHLBI)
Interstitial Lung Disease, Obstructive Sleep Apnea
10/23
10/23
NCT05716022: Hiatal Hernia and Pulmonary Involvement

Active, not recruiting
N/A
100
US
Blood Collection, Bronchoscopy
University of Virginia, CHEST Foundation
Hiatal Hernia, Interstitial Lung Disease
03/24
01/25
ASCEND, NCT05388708: ARDS in Children and ECMO Initiation Strategies Impact on Neurodevelopment

Recruiting
N/A
550
Europe, Canada, US, RoW
ECMO support, PROSpect protocolized therapies
University of Michigan, National Heart, Lung, and Blood Institute (NHLBI)
Acute Respiratory Distress Syndrome, Extracorporeal Membrane Oxygenation
09/27
09/27
NCT02678884: Head and Neck Squamous Cell Carcinoma (HNSCC)PET-CT Pilot Study

Recruiting
N/A
20
Canada
18-F FDG
University Health Network, Toronto
Head and Neck Squamous Cell Carcinoma
11/28
11/28

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