| Turkstra, Timothy P |
NCT03992092: Video Stylet vs. Flexible Bronchoscopy for C-Spine |
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| Recruiting | N/A | 50 | Canada | C-MAC VS, Flexible Bronchoscopy | Lawson Health Research Institute | Intubation;Difficult, Intubation Complication | 12/24 | 12/24 | | |
| House, Andrew A |
| Active, not recruiting | 4 | 60 | Canada | Denosumab 60 mg/ml, Prolia, Calcium and vitamin D prophylaxis, Monitoring of post-injection calcium and phosphate | Western University, Canada, ICES, Academic Medical Organization of Southwestern Ontario, Western University, The Kidney Foundation of Canada | Kidney Diseases, Dialysis; Complications, Fragility Fracture, Chronic Kidney Disease-Mineral and Bone Disorder | 12/25 | 12/25 | | |
| Completed | N/A | 12 | Canada | Control group, SLEDD with a L-MOD | Lawson Health Research Institute | COVID-19, SARS | 12/23 | 03/24 | | |
| Silverman, Michael |
| Recruiting | 4 | 8000 | Europe, Canada, RoW | Cefazolin, Penicillin, Benzylpenicillin, Penicillin G, Clindamycin, Lincomycin, Vancomycin, Daptomycin, Effectiveness of early switch to oral antibiotics, Whole body FDG PET/CT Imaging | University of Melbourne, Berry Consultants, McGill University Health Centre/Research Institute of the McGill University Health Centre, Menzies School of Health Research, Aotearoa Clinical Trials, Queensland University of Technology, Sunnybrook Health Sciences Centre, Tan Tock Seng Hospital, Telethon Kids Institute, The Peter Doherty Institute for Infection and Immunity, The University of Queensland, UMC Utrecht, Radboud University Medical Center, King's College London, Rambam Health Care Campus, University College, London, Houston Medical Research Institute | Staphylococcus Aureus Bacteremia | 12/28 | 12/28 | | |
| Active, not recruiting | 3 | 2900 | Canada | Artesunate, Imatinib, Infliximab, Dexamethasone, LSALT Peptide | Sunnybrook Health Sciences Centre, AbbVie, Apotex Inc., World Health Organization, University of British Columbia, Arch Biopartners Inc. | COVID-19 | 03/24 | 05/24 | | |
| Recruiting | 3 | 471 | Europe, US, RoW | Namodenoson, CF102, Placebo, Inactive control | Can-Fite BioPharma, CanFite BioPharma Ltd. | Hepatocellular Carcinoma, Cirrhosis | 02/25 | 10/25 | | |
NCT04247542: ACX-362E [Ibezapolstat] for Oral Treatment of Clostridioides Difficile Infection |
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| Completed | 2 | 53 | US | Ibezapolstat, ACX-362E, Vancomycin, Vancomycin oral | Acurx Pharmaceuticals Inc. | Clostridium Difficile Infection | 10/23 | 11/23 | | |
NCT04781387: Evaluation of CRS3123 vs. Oral Vancomycin in Adult Patients With Clostridioides Difficile Infection |
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| Active, not recruiting | 2 | 108 | Canada, US | CRS3123, Active Comparator | Crestone, Inc, National Institute of Allergy and Infectious Diseases (NIAID) | Clostridioides Difficile Infection | 02/24 | 04/24 | | |
| Recruiting | 2 | 20 | RoW | Namodenoson 25mg, CF102 | Can-Fite BioPharma | Pancreatic Adenocarcinoma, Pancreatic Cancer | 07/26 | 12/26 | | |
| Recruiting | 2 | 114 | Europe, RoW | Namodenoson, CF102, Placebo, Inactive control | Can-Fite BioPharma, CanFite BioPharma Ltd. | NASH - Nonalcoholic Steatohepatitis | 04/25 | 10/25 | | |
NCT04544306: Partial Oral Antimicrobials to Treat Infective Endocarditis in People Who Inject Drugs |
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| Recruiting | N/A | 50 | Canada | Partial oral antimicrobial therapy | Lawson Health Research Institute | Infective Endocarditis | 12/24 | 06/25 | | |
| Recruiting | N/A | 1800 | US | Therapeutic Hypothermia | University of Michigan, Johns Hopkins University, Medical University of South Carolina, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS) | Cardiac Arrest, Out-Of-Hospital, Hypothermia, Induced, Hypoxia-Ischemia, Brain | 07/28 | 08/28 | | |
| Mrkobrada, Marko |
| Recruiting | 4 | 2270 | Europe, Canada, RoW | Non-vitamin K oral anticoagulant (NOAC), Apixaban, Dabigatran, Edoxaban, Rivaroxaban | Population Health Research Institute, Hamilton Health Sciences Corporation | Stroke, Atrial Fibrillation | 12/26 | 12/28 | | |
| Active, not recruiting | 3 | 1720 | Canada | Cytisine, Video Messaging | Population Health Research Institute | Smoking (Tobacco) Addiction, Smoking Cessation | 07/26 | 01/27 | | |
| Recruiting | N/A | 750 | Canada | Cardiac monitoring device | Population Health Research Institute | Atrial Fibrillation, Atrial Flutter | 08/26 | 12/26 | | |
| Weir, Matthew R |
NCT06474273: TACKLE-IT Trial - Treat Acute T Cell Rejection With Evidence and Confidence in Kidney Transplant Recipients |
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| Not yet recruiting | 4 | 540 | Canada, RoW | Methylprednisolone, IV MP, Prednisone | University of Sydney, University of Manitoba | Rejection; Transplant, Kidney, Rejection; Transplant, Pancreas | 12/29 | 12/29 | | |
| Active, not recruiting | 4 | 60 | Canada | Denosumab 60 mg/ml, Prolia, Calcium and vitamin D prophylaxis, Monitoring of post-injection calcium and phosphate | Western University, Canada, ICES, Academic Medical Organization of Southwestern Ontario, Western University, The Kidney Foundation of Canada | Kidney Diseases, Dialysis; Complications, Fragility Fracture, Chronic Kidney Disease-Mineral and Bone Disorder | 12/25 | 12/25 | | |
| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
| Recruiting | 3 | 2750 | Europe, Canada, RoW | Spironolactone 25Mg Tablet, Placebo Oral Tablet | Population Health Research Institute, Canadian Institutes of Health Research (CIHR) | Endstage Renal Disease | 07/25 | 04/26 | | |
NCT04658017: GARNETâ„¢ Filter (GARNET Device) IDE Used in Chronic Hemodialysis Patients With a Bloodstream Infection |
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| Recruiting | N/A | 15 | US | GARNET device | Boa Biomedical, Inc., Avania | Bloodstream Infection | 10/21 | 12/21 | | |
PHOSPHATE, NCT03573089: Pragmatic Randomised Trial of High Or Standard PHosphAte Targets in End-stage Kidney Disease |
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| Recruiting | N/A | 3600 | Europe, Canada, RoW | Liberal phosphate target, Intensive phosphate target | The University of Queensland, National Health and Medical Research Council, Australia, Applied Health Research Centre, Cambridge University Hospitals NHS Foundation Trust, University of Otago | Kidney Failure, Chronic, Hyperphosphatemia | 12/27 | 12/28 | | |
| Recruiting | N/A | 5000 | US | | Wake Forest University Health Sciences, National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Kidney Diseases, Kidney Failure, Kidney Disease, Chronic | 12/25 | 12/25 | | |
COPE-AKI, NCT05805709: A Patient-centered Trial of a Process-of-care Intervention in Hospitalized AKI Patients: the Trial |
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| Recruiting | N/A | 2145 | US | Study Physician/Advance Practice Provider, Nurse Navigator, Pharmacist, Patient Education | University of Pittsburgh, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Acute Kidney Injury | 06/26 | 03/27 | | |
| Howard, James |
NCT05026749: Azithromycin Treatment for Respiratory Syncytial Virus-induced Respiratory Failure in Children |
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| Recruiting | 3 | 370 | US | AZM Group, Control Group | University of Alabama at Birmingham | Respiratory Syncytial Virus Infections | 07/25 | 07/26 | | |
NCT04833894 / 2020-005841-18: Evaluating the Pharmacokinetics, Pharmacodynamics, and Safety of Efgartigimod Administered Intravenously in Children with Generalized Myasthenia Gravis |
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| Recruiting | 2/3 | 12 | Europe, Canada, US, RoW | Efgartigimod IV | argenx | Generalized Myasthenia Gravis | 03/27 | 03/27 | | |
NCT04146051: Descartes-08 CAR-T Cells in Generalized Myasthenia Gravis (MG) |
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| Recruiting | 2 | 30 | Canada, US | Descartes-08 | Cartesian Therapeutics | Myasthenia Gravis, Generalized | 03/25 | 03/26 | | |
NCT03944005: Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty. |
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| Withdrawn | N/A | 532 | Europe, Canada | Spinal Anesthesia + ACB continious catheter + iPACK + Sham LIA, Spinal Anesthesia + LIA + Sham Blocks | Western University, Canada, George Eliot Hospital NHS Trust | Knee Arthroplasty | 01/24 | 05/24 | | |
| Active, not recruiting | N/A | 31 | Canada | POROUS TIBIA BASEPLATE W/ JRNY LOCK | Canadian Radiostereometric Analysis Network | Knee Osteoarthritis | 01/25 | 02/26 | | |
| Recruiting | N/A | 37 | Europe | Cardiac MRI scan, Echocardiogram scan | Imperial College London | Diastolic Dysfunction | 12/23 | 06/24 | | |
NCT06525610: Weight-Bearing CT Periprosthetic Distal Knee Fractures |
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| Not yet recruiting | N/A | 21 | NA | Periprosthetic Fracture Knee Repaired CT Scans | Lawson Health Research Institute | Periprosthetic Fracture Around Prosthetic Joint Implant Knee | 08/25 | 08/25 | | |
CATALYSTEM, NCT06564636: A Multi-Centre Study in Patients Undergoing Total Hip Arthroplasty With the Smith+Nephew ™ Primary Hip System |
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| Enrolling by invitation | N/A | 198 | Canada, US | CATALYSTEM | Smith & Nephew, Inc. | Total Hip Arthroplasty (THA), Osteoarthritis, Degenerative Joint Disease, Inflammatory Arthritis, Avascular Necrosis, Post-traumatic Arthritis, Congenital Hip Dysplasia | 12/26 | 02/30 | | |
NCT03564730: Staged Versus Simultaneous Bilateral Knee Arthroplasty |
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| Active, not recruiting | N/A | 224 | Canada | Simultaneous Knee Arthroplasty (UKA), Staged Knee Arthroplasty (UKA) | Orthopaedic Innovation Centre | Knee Osteoarthritis | 11/25 | 12/26 | | |
| Active, not recruiting | N/A | 64 | Canada | ACTIS | Canadian Radiostereometric Analysis Network, DePuy Synthes | Hip Osteoarthritis | 12/24 | 12/24 | | |
NCT04166227: Hip Arthroscopy Versus Total Hip Arthroplasty RCT |
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| Recruiting | N/A | 160 | Canada | Hip Arthroscopy, Total Hip Arthroplasty | Western University, Canada | Hip Osteoarthritis | 01/27 | 01/28 | | |
AID-MR, NCT06061822: Artificial Intelligence Delivered Cardiac Magnetic Resonance - Prospective Validation |
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| Not yet recruiting | N/A | 150 | NA | AI-assisted cardiac magnetic resonance imaging | Imperial College London, British Heart Foundation, Medical Research Council, Rosetrees Trust | Cardiovascular Diseases, Healthy Volunteers | 12/27 | 12/27 | | |
| Naudie, Douglas |
| Active, not recruiting | N/A | 31 | Canada | POROUS TIBIA BASEPLATE W/ JRNY LOCK | Canadian Radiostereometric Analysis Network | Knee Osteoarthritis | 01/25 | 02/26 | | |
NCT03554720: RSA of the ATTUNE Knee System: RCT Comparing Traditional Vs Enhanced-Fixation Device Designs |
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| Completed | N/A | 50 | Canada | ATTUNE PS Knee, ATTUNE S+ PS Knee | Canadian Radiostereometric Analysis Network, Orthopaedic Innovation Centre, Dalhousie University, London Health Sciences Centre | Knee Osteoarthritis | 11/21 | 01/24 | | |
NCT06189872: Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement |
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| Recruiting | N/A | 30 | Canada | Attune Cementless | Canadian Radiostereometric Analysis Network | Osteo Arthritis Knee | 12/26 | 06/27 | | |
NCT03564730: Staged Versus Simultaneous Bilateral Knee Arthroplasty |
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| Active, not recruiting | N/A | 224 | Canada | Simultaneous Knee Arthroplasty (UKA), Staged Knee Arthroplasty (UKA) | Orthopaedic Innovation Centre | Knee Osteoarthritis | 11/25 | 12/26 | | |
| Active, not recruiting | N/A | 64 | Canada | ACTIS | Canadian Radiostereometric Analysis Network, DePuy Synthes | Hip Osteoarthritis | 12/24 | 12/24 | | |
| McCalden, Richard |
NCT03564730: Staged Versus Simultaneous Bilateral Knee Arthroplasty |
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| Active, not recruiting | N/A | 224 | Canada | Simultaneous Knee Arthroplasty (UKA), Staged Knee Arthroplasty (UKA) | Orthopaedic Innovation Centre | Knee Osteoarthritis | 11/25 | 12/26 | | |
| Vasarhelyi, Edward M |
NCT03944005: Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty. |
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| Withdrawn | N/A | 532 | Europe, Canada | Spinal Anesthesia + ACB continious catheter + iPACK + Sham LIA, Spinal Anesthesia + LIA + Sham Blocks | Western University, Canada, George Eliot Hospital NHS Trust | Knee Arthroplasty | 01/24 | 05/24 | | |
| Active, not recruiting | N/A | 31 | Canada | POROUS TIBIA BASEPLATE W/ JRNY LOCK | Canadian Radiostereometric Analysis Network | Knee Osteoarthritis | 01/25 | 02/26 | | |
| Recruiting | N/A | 50 | Canada | Total Knee Arthroplasty with Evolution® NitrX™ Knee System, Total Knee Arthroplasty with Evolution Knee System | Lawson Health Research Institute, MicroPort Orthopedics Inc. | Total Knee Arthroplasty, Knee Osteoarthritis, Radiostereometric Analysis | 04/24 | 11/24 | | |
NCT02177227: Attune With TruMatch TM Personalized Solutions Instruments |
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| Active, not recruiting | N/A | 194 | Canada | Attune TruMatch (TM) Patient-Specific Instrumentation, TruMatch Patient-Specific Instrumentation | Lawson Health Research Institute, DePuy Orthopaedics, Johnson & Johnson Medical Companies | Obesity, Osteoarthritis | 08/24 | 08/24 | | |
NCT06189872: Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement |
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| Recruiting | N/A | 30 | Canada | Attune Cementless | Canadian Radiostereometric Analysis Network | Osteo Arthritis Knee | 12/26 | 06/27 | | |
NCT03564730: Staged Versus Simultaneous Bilateral Knee Arthroplasty |
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| Active, not recruiting | N/A | 224 | Canada | Simultaneous Knee Arthroplasty (UKA), Staged Knee Arthroplasty (UKA) | Orthopaedic Innovation Centre | Knee Osteoarthritis | 11/25 | 12/26 | | |
| Active, not recruiting | N/A | 64 | Canada | ACTIS | Canadian Radiostereometric Analysis Network, DePuy Synthes | Hip Osteoarthritis | 12/24 | 12/24 | | |
| Teeter, Matthew |
NCT03276351: Evaluation of Fixation Achievable in Revision Total Knee Arthroplasty Implementing Latest-Generation Implant Technology |
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| Completed | N/A | 12 | Canada | Long-Stemmed with Hybrid Fixation, Short-Stemmed with Augmented Fixation | Lawson Health Research Institute | Knee Osteoarthritis, Knee Arthroplasty | 12/22 | 12/22 | | |
| Active, not recruiting | N/A | 31 | Canada | POROUS TIBIA BASEPLATE W/ JRNY LOCK | Canadian Radiostereometric Analysis Network | Knee Osteoarthritis | 01/25 | 02/26 | | |
| Recruiting | N/A | 50 | Canada | Total Knee Arthroplasty with Evolution® NitrX™ Knee System, Total Knee Arthroplasty with Evolution Knee System | Lawson Health Research Institute, MicroPort Orthopedics Inc. | Total Knee Arthroplasty, Knee Osteoarthritis, Radiostereometric Analysis | 04/24 | 11/24 | | |
| Not yet recruiting | N/A | 30 | Canada | Probiotic Formula Bacillus subtilis, DE111®, Placebo | Lawson Health Research Institute | Total Knee Arthroplasty, Inflammation, Gastrointestinal Health | 04/26 | 01/27 | | |
NCT06525610: Weight-Bearing CT Periprosthetic Distal Knee Fractures |
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| Not yet recruiting | N/A | 21 | NA | Periprosthetic Fracture Knee Repaired CT Scans | Lawson Health Research Institute | Periprosthetic Fracture Around Prosthetic Joint Implant Knee | 08/25 | 08/25 | | |
NCT06189872: Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement |
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| Recruiting | N/A | 30 | Canada | Attune Cementless | Canadian Radiostereometric Analysis Network | Osteo Arthritis Knee | 12/26 | 06/27 | | |
| Active, not recruiting | N/A | 64 | Canada | ACTIS | Canadian Radiostereometric Analysis Network, DePuy Synthes | Hip Osteoarthritis | 12/24 | 12/24 | | |
| Lanting, Brent |
NCT06267482: Using ROSA for Challenging The TKA Standard of Care |
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| Recruiting | 4 | 90 | Canada | ROSA PSA Parapatellar Approach, ROSA PSA Subvastus Approach | Lawson Health Research Institute, Zimmer Biomet | Knee Osteoarthritis | 04/25 | 06/25 | | |
PEPPER, NCT02810704: Comparative Effectiveness of Pulmonary Embolism Prevention After Hip and Knee Replacement |
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| Recruiting | 4 | 20000 | Canada, US | Enteric Coated Aspirin, Aspirin, Warfarin, Coumadin, Rivaroxaban, Xarelto | Dartmouth-Hitchcock Medical Center, Patient-Centered Outcomes Research Institute, University of Maryland, Baltimore, Brigham and Women's Hospital, Northwestern University, Medical University of South Carolina | Pulmonary Embolism, Venous Thrombosis | 07/25 | 07/25 | | |
NCT03081663: Quadriceps Sparing Versus Standard Total Knee Arthroplasty |
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| Completed | N/A | 83 | Canada | Quads-Sparing Approach, quads-sparing, Medial Para-Patellar Approach, standard | Lawson Health Research Institute | Knee Osteoarthritis, Knee Arthroplasty | 12/21 | 12/21 | | |
NCT03276351: Evaluation of Fixation Achievable in Revision Total Knee Arthroplasty Implementing Latest-Generation Implant Technology |
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| Completed | N/A | 12 | Canada | Long-Stemmed with Hybrid Fixation, Short-Stemmed with Augmented Fixation | Lawson Health Research Institute | Knee Osteoarthritis, Knee Arthroplasty | 12/22 | 12/22 | | |
NCT03944005: Comparing Two Regional Anesthesia Interventions for Knee Arthroplasty. |
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| Withdrawn | N/A | 532 | Europe, Canada | Spinal Anesthesia + ACB continious catheter + iPACK + Sham LIA, Spinal Anesthesia + LIA + Sham Blocks | Western University, Canada, George Eliot Hospital NHS Trust | Knee Arthroplasty | 01/24 | 05/24 | | |
| Active, not recruiting | N/A | 31 | Canada | POROUS TIBIA BASEPLATE W/ JRNY LOCK | Canadian Radiostereometric Analysis Network | Knee Osteoarthritis | 01/25 | 02/26 | | |
| Recruiting | N/A | 33 | Canada | Cementless Total Knee Replacement | Lawson Health Research Institute, Schulich School of Medicine and Dentistry | Knee Arthroplasty, Total, Knee Osteoarthritis, Radiostereometric Analysis | 12/24 | 12/24 | | |
| Recruiting | N/A | 80 | Canada | Computer-navigated THA surgery, Standard of care THA surgery | Lawson Health Research Institute, Smith & Nephew, Inc. | Total Hip Arthroplasty, Computer-Assisted Surgery | 03/25 | 06/25 | | |
NCT05800457: The Role of Synovectomy in Pain Reduction Following Total Knee Arthroplasty |
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| Recruiting | N/A | 300 | Canada | Partial synovectomy | Lawson Health Research Institute | Osteoarthritis, Knee | 12/24 | 12/24 | | |
SensorRCT, NCT04775719: Pilot Sensor Randomized Controlled Trial: Setting Expectations to Increase Satisfactory Outcomes After Total Knee Replacement |
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| Active, not recruiting | N/A | 40 | Canada | Patient-Specific Prediction of Functional Outcome, Standard Pre-Operative Total Knee Arthroplasty Information | Lawson Health Research Institute | Patient Satisfaction | 02/25 | 02/25 | | |
| Not yet recruiting | N/A | 30 | Canada | Probiotic Formula Bacillus subtilis, DE111®, Placebo | Lawson Health Research Institute | Total Knee Arthroplasty, Inflammation, Gastrointestinal Health | 04/26 | 01/27 | | |
NCT05893563: Corail Stability At 5-Years Post-Total Hip Arthroplasty |
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| Recruiting | N/A | 79 | Canada | Standard Post-Operative Clinic Visit, Study-Specific Outcomes | Lawson Health Research Institute | Total Hip Arthroplasty | 12/24 | 12/24 | | |
NCT06525610: Weight-Bearing CT Periprosthetic Distal Knee Fractures |
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| Not yet recruiting | N/A | 21 | NA | Periprosthetic Fracture Knee Repaired CT Scans | Lawson Health Research Institute | Periprosthetic Fracture Around Prosthetic Joint Implant Knee | 08/25 | 08/25 | | |
NCT06189872: Radiographic Migration Analysis of the ATTUNE Cementless CR Fixed-Bearing Total Knee Replacement |
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| Recruiting | N/A | 30 | Canada | Attune Cementless | Canadian Radiostereometric Analysis Network | Osteo Arthritis Knee | 12/26 | 06/27 | | |
NCT03564730: Staged Versus Simultaneous Bilateral Knee Arthroplasty |
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| Active, not recruiting | N/A | 224 | Canada | Simultaneous Knee Arthroplasty (UKA), Staged Knee Arthroplasty (UKA) | Orthopaedic Innovation Centre | Knee Osteoarthritis | 11/25 | 12/26 | | |
| Recruiting | N/A | 80 | Canada | Total Hip Arthroplasty, Total hip replacement | Western University, Canada | Osteoarthritis, Hip | 12/24 | 12/24 | | |
| Recruiting | N/A | 300 | Canada | Outpatient, Inpatient | Lawson Health Research Institute | Osteoarthritis, Knee | 12/24 | 12/25 | | |
| Active, not recruiting | N/A | 64 | Canada | ACTIS | Canadian Radiostereometric Analysis Network, DePuy Synthes | Hip Osteoarthritis | 12/24 | 12/24 | | |
| Recruiting | N/A | 7600 | Canada | XPERIENCE Advanced Surgical Irrigation, XP, Dilute Betadine, DB, Providone-Iodine | Ottawa Hospital Research Institute, Next Science TM | Hip Osteoarthritis, Hip Arthritis, Knee Osteoarthritis, Knee Arthritis | 03/27 | 12/27 | | |
NCT04166227: Hip Arthroscopy Versus Total Hip Arthroplasty RCT |
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| Recruiting | N/A | 160 | Canada | Hip Arthroscopy, Total Hip Arthroplasty | Western University, Canada | Hip Osteoarthritis | 01/27 | 01/28 | | |
| McIntyre, Christopher W |
| Recruiting | 2 | 10 | Canada | Interdialytic peritoneal ultrafiltration with 10% dextrose solution | Lawson Health Research Institute, Sequana Medical N.V. | End Stage Renal Disease on Dialysis, Hemodialysis, Peritoneal Dialysis, Nonosmotic Sodium Storage | 11/24 | 12/24 | | |
NCT05185999: Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients |
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| Completed | 1 | 10 | Canada | Icodextrin/Dextrose | Lawson Health Research Institute | Chronic Kidney Failure | 10/23 | 10/23 | | |
| Active, not recruiting | N/A | 18 | Canada | Reveal LINQ insertable cardiac monitoring system | Lawson Health Research Institute | Arrythmia, Cardiac, Sudden Cardiac Death, Hemodialysis | 09/24 | 12/24 | | |
NCT03640858: Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL |
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| Completed | N/A | 82 | Canada | Theranova Dialyzer | London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's, Baxter Healthcare Corporation | End Stage Renal Disease | 04/23 | 04/23 | | |
| Recruiting | N/A | 20 | Canada | | Lawson Health Research Institute | Chronic Kidney Disease Requiring Chronic Dialysis, Interdialytic Weight Gain | 09/24 | 12/24 | | |
| Recruiting | N/A | 200 | Canada | Sodium-23 MRI | Lawson Health Research Institute | Chronic Kidney Disease, Nephrolithiasis, ADPKD | 12/24 | 12/24 | | |
| Recruiting | N/A | 37 | Canada | RespirAct | Lawson Health Research Institute, Heart and Stroke Foundation of Canada | Chronic Kidney Failure | 12/24 | 12/24 | | |
NCT03004547: Sodium Deposition in Soft Tissues of Patients With Kidney Disease |
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| Recruiting | N/A | 400 | Canada | Measuring sodium content | Chris McIntyre | Haemodialysis Complication | 12/24 | 12/24 | | |
| Completed | N/A | 12 | Canada | Control group, SLEDD with a L-MOD | Lawson Health Research Institute | COVID-19, SARS | 12/23 | 03/24 | | |
| Recruiting | N/A | 50 | Canada | Furosemide Injection | Lawson Health Research Institute | Cardio-Renal Syndrome | 12/24 | 12/24 | | |
NCT04848636: Cardiac Tissue Sodium Assessment in CKD Patients Using Sodium MRI |
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| Recruiting | N/A | 150 | Canada | Cardiac Sodium and Proton MRI | Lawson Health Research Institute | Chronic Kidney Diseases, Dialysis; Complications, Sodium Retention | 07/25 | 12/25 | | |
NCT06032208: An Extension to Assess the Effect of Expanded Dialysis on Patient Reported Symptoms Using LEVIL |
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| Recruiting | N/A | 100 | Canada | Theranova Dialyzer | London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's, Baxter Healthcare Corporation | End Stage Renal Disease | 12/25 | 12/25 | | |
NCT06735378: Exercise Preconditioning to Protect Against Dialysis-induced Cardiac Injury |
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| Not yet recruiting | N/A | 30 | Canada | Intradialytic Cycling | London Health Sciences Centre Research Institute and Lawson Research Institute of St. Joseph's | Hemodialysis, Cardioprotection | 10/25 | 12/25 | | |
| Jog, Mandar |
NCT03343574: Cardiovascular Effects of Exercise in Patients With Parkinson's Disease |
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| Active, not recruiting | N/A | 300 | Canada | Abdominal Strengthening Exercise, Abdominal Exercise | Faizan Ahmed | Parkinson Disease, Orthostatic Hypotension | 08/20 | 11/24 | | |
NCT04429230: Non-invasive Brain Stimulation in Huntington's Disease |
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| Not yet recruiting | N/A | 15 | NA | Active Transcranial pulsed current stimulation (tPCS), Sham Transcranial pulsed current stimulation (tPCS) | Western University, Canada | Huntington Disease | 09/22 | 12/22 | | |
tPCS, NCT05625620: Cerebellar-spinal Transcranial Pulsed Current Stimulation () for Treatment of Neurodegenerative Ataxia |
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| Recruiting | N/A | 15 | Canada | Active Transcranial Pulse Current Stimulation, Sham Transcranial Pulse Current Stimulation | Western University, Canada | Cerebellar Ataxia | 06/24 | 12/24 | | |
| Somerville, Lyndsay |
| Terminated | 2 | 112 | Europe, Canada, RoW | ATX-101, bupivacaine hydrochloride without epinephrine | Allay Therapeutics, Inc. | Acute Postoperative Pain | 01/24 | 01/24 | | |
| Recruiting | N/A | 33 | Canada | Cementless Total Knee Replacement | Lawson Health Research Institute, Schulich School of Medicine and Dentistry | Knee Arthroplasty, Total, Knee Osteoarthritis, Radiostereometric Analysis | 12/24 | 12/24 | | |
| Recruiting | N/A | 80 | Canada | Computer-navigated THA surgery, Standard of care THA surgery | Lawson Health Research Institute, Smith & Nephew, Inc. | Total Hip Arthroplasty, Computer-Assisted Surgery | 03/25 | 06/25 | | |
| Not yet recruiting | N/A | 30 | Canada | Probiotic Formula Bacillus subtilis, DE111®, Placebo | Lawson Health Research Institute | Total Knee Arthroplasty, Inflammation, Gastrointestinal Health | 04/26 | 01/27 | | |
NCT05893563: Corail Stability At 5-Years Post-Total Hip Arthroplasty |
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| Recruiting | N/A | 79 | Canada | Standard Post-Operative Clinic Visit, Study-Specific Outcomes | Lawson Health Research Institute | Total Hip Arthroplasty | 12/24 | 12/24 | | |
NCT06525610: Weight-Bearing CT Periprosthetic Distal Knee Fractures |
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| Not yet recruiting | N/A | 21 | NA | Periprosthetic Fracture Knee Repaired CT Scans | Lawson Health Research Institute | Periprosthetic Fracture Around Prosthetic Joint Implant Knee | 08/25 | 08/25 | | |
| Recruiting | N/A | 80 | Canada | Total Hip Arthroplasty, Total hip replacement | Western University, Canada | Osteoarthritis, Hip | 12/24 | 12/24 | | |
| Recruiting | N/A | 300 | Canada | Outpatient, Inpatient | Lawson Health Research Institute | Osteoarthritis, Knee | 12/24 | 12/25 | | |
| Penny, Jarrin |
NCT05185999: Icodextrin Study to Test Short-Term Safety, Tolerability and Preliminary Efficacy of Sodium-Free Solution in PD Patients |
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| Completed | 1 | 10 | Canada | Icodextrin/Dextrose | Lawson Health Research Institute | Chronic Kidney Failure | 10/23 | 10/23 | | |
