University of North Carolina (UNC) Project-Malawi
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 5 Trials 
6 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Chinula, Lameck
COVENANT, NCT03284866: HPV Vaccine Therapy in Reducing High-Grade Cervical Lesions in Patients With HIV and HPV

Active, not recruiting
3
536
RoW
Laboratory Biomarker Analysis, Recombinant Human Papillomavirus Nonavalent Vaccine, Gardasil 9, Nonavalent HPV VLP Vaccine, Recombinant HPV Nonavalent Vaccine, Recombinant Human Papillomavirus 9-valent Vaccine, Recombinant HPV 9-valent Vaccine, Saline, Sodium Chloride 0.9%
AIDS Malignancy Consortium, National Cancer Institute (NCI), University of Arkansas, AIDS and Cancer Specimen Resource, Merck Sharp & Dohme LLC, The Emmes Company, LLC, University of California, Los Angeles
AIDS-Related Human Papillomavirus Infection, High Grade Cervical Squamous Intraepithelial Neoplasia, HIV Infection
12/24
03/27
NCT03601806: Pomalidomide in Treating Patients With Kaposi Sarcoma and Human Immunodeficiency Virus Infection

Active, not recruiting
2
26
RoW
Laboratory Biomarker Analysis, Pomalidomide, 4-Amino thalidomide, Actimid, CC-4047, Imnovid, Pomalyst
AIDS Malignancy Consortium, National Cancer Institute (NCI), The Emmes Company, LLC, University of Arkansas, Montefiore Medical Center, University of Stellenbosch, Weill Medical College of Cornell University, University of California, Los Angeles
Human Immunodeficiency Virus 1 Positive, Skin Kaposi Sarcoma
11/24
01/26
NCT05797662: A Study of Propranolol to Treat Kaposi Sarcoma

Not yet recruiting
2
25
RoW
Propranolol
AIDS Malignancy Consortium, National Cancer Institute (NCI)
Kaposi Sarcoma
08/28
08/29
NCT05362955: 5-fluorouracil Following Cervical Intraepithelial Neoplasia Treatment Among HIV-positive Women in East Africa

Completed
1
12
RoW
Intravaginal 5-Fluorouracil (5-FU)
UNC Lineberger Comprehensive Cancer Center
CIN 2/3, HIV Infections
02/24
02/24
NCT04092257: HPV-Based Screen-and-Treat Demonstration Project in Lilongwe

Active, not recruiting
N/A
1250
RoW
VIA and thermocoagulation
UNC Lineberger Comprehensive Cancer Center, National Cancer Institute (NCI), United States Agency for International Development (USAID)
HPV Infection, Cervical Cancer, HIV Infections
02/24
02/25
NJIRA, NCT06200545: Improving HIV Prevention Among Heterosexual Cisgender Men Seeking STI Services in Malawi

Enrolling by invitation
N/A
215
RoW
PrEP eligibility assessment, Rapid HIV antibody testing prior to provision and/or refill of PrEP, PrEP follow-up with a PrEP nurse in accordance with contemporary PrEP guidelines, Evaluation of barriers and facilitators to ongoing PrEP use, Point of contact STI testing to inform counseling regarding ongoing PrEP care engagement, Tracing for any missed PrEP visits, Offering a PrEP "restart" kit for cisgender men who choose to discontinue PrEP during the follow-up period
HIV Prevention Trials Network, Division of AIDS, US National Institute of Allergy and Infectious Diseases, National Institute of Allergy and Infectious Diseases (NIAID)
HIV Infection, Sexually Transmitted Infections, Pre-exposure Prophylaxis, Systems Navigation
06/25
06/25

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