| Wang, Lin Wei |
NCT06285370: A Study to Evaluate the Efficacy and Safety of KW-0761 in Chinese Subjects With Mycosis Fungoides or Sézary Syndrome Previously Treated With Systemic Therapy |
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| Recruiting | 4 | 20 | RoW | Mogamulizumab | Kyowa Kirin China Pharmaceutical Co., Ltd. | Cutaneous T-Cell Lymphoma | 10/25 | 01/26 | | |
NCT05950646: Mini-dose Dexmedetomidine-Esketamine Infusion and Perioperative Sleep Quality |
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| Recruiting | 4 | 154 | RoW | Dexmedetomidine, Esketamine, Normal saline | Peking University First Hospital, Beijing Hospital | Old Age, Knee Replacement Surgery, Hip Replacement Surgery, Dexmedetomidine, Esketamine, Sleep Quality | 12/24 | 12/27 | | |
NCT05043870: Combined Immunosuppression for Pediatric Crohn's Disease |
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| Recruiting | 4 | 128 | RoW | Infliximab and immunosuppressives, IFX, IMMs, AZA, MTX, Infliximab, IFX | Children's Hospital of Fudan University | Crohn Disease, Infliximab, Immunosuppression, Children, Only | 10/25 | 12/25 | | |
NCT05525637: Safety and Efficacy Study of YZJ-1139 in Insomnia Disorder |
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| Recruiting | 3 | 1041 | RoW | YZJ-1139 20mg, YZJ-1139 40mg, Placebo | Shanghai Haiyan Pharmaceutical Technology Co., Ltd. | Insomnia Disorder | 12/24 | 12/24 | | |
| Recruiting | 3 | 918 | Europe, Canada, Japan, RoW | Zanidatamab, ZW25, JZP598, Tislelizumab, Trastuzumab, Herceptin®, Capecitabine, Oxaliplatin, Cisplatin, 5-Fluorouracil | Jazz Pharmaceuticals, BeiGene, Ltd. | Gastric Neoplasms, Gastroesophageal Adenocarcinoma, Esophageal Adenocarcinoma | 05/25 | 05/26 | | |
| Recruiting | 3 | 778 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Crohn's Disease | 11/24 | 12/26 | | |
| Recruiting | 3 | 400 | Europe, Canada, Japan, US, RoW | tucatinib, TUKYSA, ONT-380, ARRY-380, PF-07265792, trastuzumab, Herceptin, bevacizumab, Avastin, cetuximab, Erbitux, oxaliplatin, leucovorin, levoleucovorin, fluorouracil | Seagen Inc., Merck Sharp & Dohme LLC | Colorectal Neoplasms | 08/25 | 04/28 | | |
NCT06004856: Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Chronic Primary Immune Thrombocytopenia |
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| Recruiting | 3 | 195 | RoW | Orelabrutinib, Placebo | Beijing InnoCare Pharma Tech Co., Ltd. | Chronic Primary Immune Thrombocytopenia (ITP) | 12/25 | 04/26 | | |
NCT03221036: Efficacy and Safety of Vedolizumab IV in Chinese Participants With Ulcerative Colitis |
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| Recruiting | 3 | 402 | RoW | Vedolizumab IV, Placebo | Takeda | Moderately to Severely Active Ulcerative Colitis | 05/28 | 07/28 | | |
NCT05145907: Study to Evaluate Safety and Efficacy of TJ107 Combine With PD-1 in Patients With Solid Tumors |
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| Active, not recruiting | 2 | 133 | RoW | TJ107 +Pembrolizumab | TJ Biopharma Co., Ltd. | Triple-negative Breast Cancer, Head and Neck Squamous Cell Carcinoma | 06/24 | 12/24 | | |
NCT06233461: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease |
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| Recruiting | 2 | 268 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Crohn's Disease | 09/26 | 07/27 | | |
TranStar102, NCT04495296: A Trial to Evaluate Safety, Tolerability, Pharmacokinetics and Preliminary Efficacy of TST001 in Advanced or Metastatic Solid Tumors |
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| Recruiting | 1/2 | 320 | RoW | TST001, Oxaliplatin, Capecitabine, Paclitaxel, Gemcitabine, Cisplatin, Nivolumab | Suzhou Transcenta Therapeutics Co., Ltd., Bristol-Myers Squibb | Advanced Cancer | 02/25 | 05/25 | | |
NCT05690581: Safety, Tolerability, Pharmacokinetic Characteristics, and Efficacy of CM369 in Advanced Solid Tumors & Hematologic Malignancies |
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| Recruiting | 1 | 146 | RoW | CM369 | Beijing InnoCare Pharma Tech Co., Ltd. | Advanced Solid Tumors and Hematologic Malignancies | 10/25 | 02/26 | | |
| Recruiting | N/A | 10254 | RoW | | Limeng Chen | Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder | 12/24 | 12/24 | | |
NCT06256315: Hyper-ERAS Program for Highly Selective Colorectal Cancer Patients |
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| Recruiting | N/A | 160 | RoW | Hyper-ERAS Program | Peking University Cancer Hospital & Institute | Colorectal Cancer, ERAS | 06/25 | 08/25 | | |
NCT06256627: The Maintenance Treatment of "ITIVA" in AML Patients |
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| Recruiting | N/A | 130 | RoW | recombinant human interference'- α- 1b, interleukin-2, thalidomide, Venentoclax and Azacitidine | Henan Cancer Hospital | Acute Myeloid Leukemia, Maintenance Treatment, Minor Residue Disease, Interferon-α-1b, Interleukin-2, Thalidomide, Venentoclax, Azacitidine | 03/25 | 05/27 | | |
NCT05246007: Nocturnal Low-dose Dexmedetomidine Infusion and Perioperative Sleep Quality |
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| Not yet recruiting | N/A | 432 | RoW | Dexmedetomidine, Dexmedetomidine for infusion, Normal Saline, Normal Saline for infusion | Peking University First Hospital, Beijing Hospital | Old Age, Knee Replacement Surgery, Hip Replacement Surgery, Dexmedetomidine, Sleep Quality | 12/23 | 12/26 | | |
NCT06209099: Organ Preservation First Strategy and Intentional Watch and Wait for MRI Defined Low-risk Rectal Cancer |
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| Recruiting | N/A | 67 | RoW | Nonoperative Management (NOM), Local Excision (LE), Total Mesorectal Excision (TME) | Peking University Cancer Hospital & Institute | Rectal Cancer | 09/25 | 11/25 | | |
| Recruiting | N/A | 1247 | Europe, Canada, US | Edwards PASCAL System, Transcatheter Mitral Valve repair (TMVr), Abbott Mitraclip System | Edwards Lifesciences | Degenerative Mitral Valve Disease, Mitral Regurgitation, Mitral Insufficiency, Functional Mitral Regurgitation | 01/25 | 04/30 | | |
NCT05782881: High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program |
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| Recruiting | N/A | 16000 | RoW | phone calls and encouraging patients' lifestyle change and medication adherence, Statin, Angiotensin-converting enzyme inhibitor, Angiotensin receptor neprilysin inhibitor, Glucagon-like peptide-1, Sodium-dependent glucose transporters 2 | Wuhan Union Hospital, China, Peking University First Hospital | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Coronary Disease | 12/23 | 12/24 | | |
| Not yet recruiting | N/A | 1500 | RoW | adrenal venous sampling | Chinese Academy of Medical Sciences, Fuwai Hospital | Hyperaldosteronism | 12/26 | 12/26 | | |
EHCONSGDMC, NCT05911893: the Effect of High Caloric Oral Nutritional Supplements on Growth and Development of Malnourished Children |
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| Not yet recruiting | N/A | 800 | RoW | high caloric oral nutritional supplements, high-energy total nutrition formula, nutritional education, dietary guidance | Children's Hospital of Chongqing Medical University, Anhui Provincial Children's Hospital, Baoji Maternity and Child Healthcare Hospital, Chengdu Women's and Children's Central Hospital, Guiyang Maternity and Child Health Care Hospital, Guangzhou Women and Children's Medical Center, Hunan Children's Hospital, Jiangxi Maternal and Child Health Hospital, Kunming Children's Hospital, Nanjing Maternity and Child Health Care Hospital, Children's Hospital of The Capital Institute of Pediatrics, Xianyang Children's Hospital, Nestle Health Science | Malnutrition, Child, Malnourishment, Nutritional Deficiency, Undernutrition | 02/25 | 06/25 | | |
TALENTop, NCT04649489: A Study to Evaluate Efficacy and Safety of Hepatic Resection for Liver Cancer with PVTT, HVTT or IVCTT After Initial Ate/Bev |
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| Active, not recruiting | N/A | 501 | RoW | Atezolizumab, Bevacizumab, Surgery | Jia Fan | Venous Thrombosis | 08/27 | 03/28 | | |
NCT05670275: Microecology and Host Immunity in Patients With Severe COVID-19 Infection |
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| Recruiting | N/A | 200 | RoW | | Chinese PLA General Hospital | Microbiome,Immune Function, Critically Ill | 06/23 | 06/23 | | |
| Gao, Feng |
NCT04683406: A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A |
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| Completed | 3 | 750 | RoW | ZSP1273 600 mg, Placebo to Oseltamivir, Oseltamivir(oral), Placebo to ZSP1273 | Guangdong Raynovent Biotech Co., Ltd | Influenza A | 04/23 | 05/23 | | |
| Recruiting | 3 | 2100 | Europe, Canada, Japan, US, RoW | Rimegepant/BHV3000, Matching placebo | Pfizer | Pediatric Migraine | 01/29 | 01/29 | | |
| Recruiting | 2/3 | 104 | RoW | B007, Placebo | Shanghai Jiaolian Drug Research and Development Co., Ltd, Shanghai Pharmaceuticals Holding Co., Ltd | Generalized Myasthenia Gravis | 06/26 | 06/26 | | |
NCT06413654: A Clinical Study of B001 Injection in the Treatment of Neuromyelitis Optica Spectrum Disorders(NMOSD) |
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| Recruiting | 2/3 | 132 | RoW | B001, Placebo | Shanghai Jiaolian Drug Research and Development Co., Ltd, Shanghai Pharmaceuticals Holding Co., Ltd | Neuromyelitis Optica Spectrum Disorders | 10/27 | 02/29 | | |
NCT04543279: Fostamatinib as a Single Agent or in Combination With Ruxolitinib for Treatment of Patients With Myelofibrosis With Severe Thrombocytopenia |
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| Terminated | 2 | 3 | US | Fostamatinib, Tavalisse, Ruxolitinib, Jakafi | Washington University School of Medicine, Rigel Pharmaceuticals | Myelofibrosis, Thrombocytopenia | 07/22 | 07/22 | | |
NCT06483100: Measurable Residual Disease-Guided Post-Transplant Elranatamab Maintenance |
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| Recruiting | 2 | 65 | US | Elrantamab, clonoSEQ | Washington University School of Medicine, National Comprehensive Cancer Network, Pfizer, Rapid Novor | Multiple Myeloma | 12/31 | 12/31 | | |
NCT06445166: Propranolol for the Treatment of Kaposi Sarcoma in Adults |
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| Not yet recruiting | 2 | 25 | US | Propranolol Hydrochloride | Washington University School of Medicine | Kaposi Sarcoma | 06/27 | 12/27 | | |
CNS-PHLAT, NCT06687772: CNS-Relapse Prevention in High-Risk Diffuse Large B-cell Lymphoma with Thiotepa-based Autologous Stem Cell Transplant |
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| Not yet recruiting | 2 | 36 | US | Thiotepa, Carmustine, Autologous Stem Cell Transplant, ASCT, Anthracycline-based induction chemotherapy | Washington University School of Medicine | Diffuse Large B Cell Lymphoma | 08/27 | 08/29 | | |
NCT06044350: A Clinical Trial of BAT4406F Injection in Patients with Neuromyelitis Optica Spectrum Disorders |
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| Recruiting | 2 | 162 | RoW | BAT4406F Injection, BAT4406F Placebos | Bio-Thera Solutions | Optic Neuromyelitis Spectrum Disease | 05/25 | 05/26 | | |
NCT04354025: Cytokine-induced Memory-like NK Cells in Combination With Chemotherapy in Pediatric Patents With Refractory or Relapsed AML |
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| Withdrawn | 2 | 48 | NA | Cytokine induced memory-like NK cells, CIML NK cells, Fludarabine, Ara-C, Cytarabine, G-CSF, Filgrastim, Interleukin-2, IL-2, Leukapheresis | Washington University School of Medicine | Refractory Acute Myeloid Leukemia, Relapsed Acute Myeloid Leukemia | 09/26 | 07/28 | | |
NCT05820763: Selinexor and Lenalidomide for Consolidation and Maintenance Treatment in Multiple Myeloma Post-transplant |
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| Withdrawn | 2 | 35 | NA | Selinexor, EXPOVIO, KPT-330, Lenalidomide, Revlimid, Dexamethasone, Decadron | Washington University School of Medicine, Karyopharm Therapeutics Inc | Multiple Myeloma, Myeloma-Associated Amyloidosis | 01/27 | 01/27 | | |
NCT05483010: Statins in Patients With Clonal Cytopenia of Undetermined Significance (CCUS) and Myelodysplastic Syndromes (MDS) |
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| Recruiting | 2 | 16 | US | Atorvastatin, Lipitor, Rosuvastatin, Crestor | Washington University School of Medicine | Clonal Cytopenia of Undetermined Significance, Myelodysplastic Syndromes | 05/27 | 05/27 | | |
NCT02756962: Improving Risk Assessment of AML With a Precision Genomic Strategy to Assess Mutation Clearance |
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| Active, not recruiting | 2 | 107 | US | Cytarabine, Ara-C, Cytosar-U, Tarabine-PFS, AraC, Allogeneic stem cell transplant, AlloSCT, Bone marrow aspiration, Punch skin biopsy, ClinSeq | Washington University School of Medicine, The Leukemia and Lymphoma Society, American Society of Hematology | Acute Myeloid Leukemia | 07/29 | 07/29 | | |
ABCD-NK, NCT06158828: Pilot Study of Memory-like Natural Killer (ML NK) Cells After TCRαβ T Cell Depleted Haploidentical Transplant in AML |
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| Recruiting | 1/2 | 48 | US | Rabbit Anti thymocyte globulin, rATG, Busulfan, Fludarabine, Thiotepa, Melphalan, Evolema, Alkeran, TCR alpha beta / CD19+ depleted haploidentical hematopoietic progenitor cell graft, TCRab/CD19+ depleted haploidentical HPC graft, memory-like natural killer cells, ML NK cells, IL-2, Plerixafor, Granulocyte Colony-Stimulating Factor, G-CSF, CliniMACS | Washington University School of Medicine, The Leukemia and Lymphoma Society, Rising Tide Foundation, St. Louis Children's Hospital Foundation | AML, Childhood, Aml, Acute Myeloid Leukemia, Pediatric, Acute Myeloid Leukemia | 09/28 | 05/30 | | |
PRiME II, NCT06639607: PEP-CMV + Nivolumab for Newly Diagnosed Diffuse Midline Glioma/High-grade Glioma and Recurrent Diffuse Midline Glioma/High-grade Glioma, Medulloblastoma, and Ependymoma |
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| Not yet recruiting | 1/2 | 68 | US | PEP-CMV vaccine, Tetanus booster, Td booster, Nivolumab, Temozolomide | Washington University School of Medicine, National Cancer Institute (NCI) | Diffuse Midline Glioma, Diffuse Midline High-grade Glioma, Medulloblastoma, Ependymoma | 07/30 | 05/42 | | |
NCT04077866: B7-H3 CAR-T for Recurrent or Refractory Glioblastoma |
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| Recruiting | 1/2 | 40 | RoW | Temozolomide, TMZ, B7-H3 CAR-T | Second Affiliated Hospital, School of Medicine, Zhejiang University, Ningbo Yinzhou People's Hospital, Huizhou Municipal Central Hospital, BoYuan RunSheng Pharma (Hangzhou) Co., Ltd. | Recurrent Glioblastoma, Refractory Glioblastoma | 06/25 | 08/25 | | |
NCT06185751: Safety and Efficacy of CS1 CAR-T (WS-CART-CS1) in Subjects With Multiple Myeloma |
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| Recruiting | 1 | 25 | US | WS-CART-CS1, Lymphodepleting chemotherapy | Washington University School of Medicine, Paula C. & Rodger O. Riney Blood Cancer Research | Multiple Myeloma | 08/29 | 08/40 | | |
NCT06623630: Lymphodepleting Total Body Irradiation (TBI) Plus Cyclophosphamide Prior to Ciltacabtagene Autoleucel (Carvykti; Cilta-cel) for Multiple Myeloma (MM) Patients With Impaired Renal Function |
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| Recruiting | 1 | 12 | US | Cyclophosphamide, Ciltacabtagene Autoleucel, Carvykti, cilta-cel, Total body irradiation, TBI | Washington University School of Medicine, American Cancer Society, Inc., Cures Within Reach | Multiple Myeloma | 04/26 | 03/27 | | |
NCT05743595: Neoantigen-based Personalized DNA Vaccine With Retifanlimab PD-1 Blockade Therapy in Patients With Newly Diagnosed, Unmethylated Glioblastoma |
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| Recruiting | 1 | 12 | US | Personalized Neoantigen DNA vaccine, Retifanlimab, INCMGA00012, MGA012, TDS-IM v 2.0 electroporation device | Washington University School of Medicine, Incyte Corporation, PapiVax Biotech, Inc., The Foundation for Barnes-Jewish Hospital | Unmethylated Glioblastoma | 01/26 | 10/28 | | |
NCT06523699: Impact of Recombinant Human Interleukin-7 (CYT107) on Tumor Clearance and Immune Reconstitution in Multiple Myeloma Patients After Autologous Hematopoietic Cell Transplant |
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| Not yet recruiting | 1 | 30 | US | Recombinant glycosylated human interleukin-7, CYT107, r-hIL-7, Melphalan, Autologous hematopoietic cell transplant, AHCT | Washington University School of Medicine, Revimmune | Multiple Myeloma | 01/29 | 01/29 | | |
NCT06529822: Personalized Cancer Vaccine (PCV) Strategy in Patients With Solid Tumors and Molecular Residual Disease |
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| Not yet recruiting | 1 | 16 | US | Synthetic long peptide personalized cancer vaccine, PCV, Poly ICLC, Hiltonol, Signatera assay | Washington University School of Medicine, Natera, Inc. | Muscle-Invasive Bladder Carcinoma | 09/28 | 08/33 | | |
NCT05044039: Duvelisib Following Chimeric Antigen Receptor T-Cell Therapy |
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| Recruiting | 1 | 43 | US | Duvelisib | Washington University School of Medicine, SecuraBio, The Foundation for Barnes-Jewish Hospital, National Cancer Institute (NCI) | Non-hodgkin Lymphoma, Acute Lymphocytic Leukemia | 12/25 | 05/30 | | |
NCT05412290: Mosunetuzumab Consolidation Therapy After autoSCT in r/r Aggressive B Cell Lymphoma |
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| Recruiting | 1 | 15 | US | Mosunetuzumab, RO7030816, BTCT4465A | Washington University School of Medicine, Genentech, Inc. | B Cell Lymphoma, Aggressive Lymphoma, Diffuse Large B Cell Lymphoma, High-grade B-cell Lymphoma, Transformed Lymphoma, Follicular Lymphoma Grade 3 | 07/27 | 06/29 | | |
NCT05111353: Neoantigen Vaccines in Pancreatic Cancer in the Window Prior to Surgery |
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| Recruiting | 1 | 36 | US | Optimized neoantigen synthetic long peptide vaccine, Poly-ICLC, Hiltonol | Washington University School of Medicine, National Cancer Institute (NCI), Leidos, UNICO Foundation | Pancreas Cancer, Pancreatic Cancer, Cancer of the Pancreas | 12/25 | 12/27 | | |
NCT06008808: Ruxolitinib for the Prophylaxis of Graft-Versus-Host Disease and Cytokine Release Syndrome After T-cell Replete Haploidentical Peripheral Blood Hematopoietic Cell Transplantation |
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| Recruiting | 1 | 49 | US | Ruxolitinib, Jakafi | Washington University School of Medicine, Incyte Corporation | Graft Vs Host Disease, Graft-versus-host-disease, Graft Versus Host Disease | 09/26 | 12/26 | | |
NCT05377827: Dose-Escalation and Dose-Expansion Study to Evaluate the Safety and Tolerability of Anti-CD7 Allogeneic CAR T-Cells (WU-CART-007) in Patients With CD7+ Hematologic Malignancies |
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| Recruiting | 1 | 54 | US | WU-CART-007 | Washington University School of Medicine, Wugen, Inc. | T-Cell Non-Hodgkin Lymphoma, Acute Myeloid Leukemia, Angioimmunoblastic T-cell Lymphoma, Enteropathy-Associated T-Cell Lymphoma, Monomorphic Epitheliotropic Intestinal T-Cell Lymphoma, Peripheral T Cell Lymphoma, Anaplastic Large Cell Lymphoma, Adult T Cell Leukemia, Adult T Cell Lymphoma, T Cell Prolymphocytic Leukemia, Extranodal NK/T-cell Lymphoma, Transformed Mycosis Fungoides, Sezary Syndrome, Primary Cutaneous Gamma-Delta T-Cell Lymphoma, Hepatosplenic T-cell Lymphoma | 04/26 | 04/26 | | |
NCT05187182: CA-4948 in Combination With FOLFOX/PD-1 Inhibitor +/- Trastuzumab for Untreated Unresectable Gastric and Esophageal Cancer |
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| Recruiting | 1 | 42 | US | CA-4948, Nivolumab, Opdivo, Pembrolizumab, Keytruda, Trastuzumab, Herceptin, mFOLFOX7 | Washington University School of Medicine, Curis, Inc., The Foundation for Barnes-Jewish Hospital | Gastric Cancer, Esophageal Cancer, Stomach Cancer, Esophagus Cancer, Gastroesophageal Junction Cancer | 09/27 | 06/28 | | |
NCT05011422: Haploidentical Hematopoietic Stem Cell Transplantation With Ex Vivo TCR Alpha/Beta and CD19 Depletion in Pediatric Hematologic Malignancies |
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| Recruiting | 1 | 32 | US | Ex Vivo T-cell receptor alpha-beta and CD19+ Depletion using CliniMACs Plus | Washington University School of Medicine | Pediatric Hematologic Malignancies | 11/27 | 11/27 | | |
NCT05629546: Memory-Like Natural Killer Cells With Nivolumab and Relatlimab in Advanced or Metastatic Melanoma After Progression on Checkpoint Inhibitors |
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| Recruiting | 1 | 33 | US | Cytokine-induced memory-like natural killer cells, ML NK cells, CIML, Relatilmab, Opdualag, Nivolumab | Washington University School of Medicine, Melanoma Research Alliance, Rising Tide Foundation | Advanced Melanoma, Metastatic Melanoma | 02/29 | 11/30 | | |
| Recruiting | N/A | 25000 | RoW | | Second Affiliated Hospital, School of Medicine, Zhejiang University, The People's Hospital of Haiyan, Taizhou First People's Hospital, The First People's Hospital of Pinghu, The 2nd People's Hospital of Quzhou | Stroke, Intracerebral Hemorrhage | 12/30 | 12/33 | | |
NCT05472025: Clinical Study of Combined Carotid Artery With Inferior Vena Cava Ultrasonography to Predict Hypotension After Induction of General Anesthesia |
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| Recruiting | N/A | 106 | RoW | | Tongji Hospital | Ultrasound Guidance | 04/23 | 04/23 | | |
ANGEL-REBOOT, NCT05122286: Randomized Study of Bailout Intracranial Angioplasty Following Thrombectomy for Acute Large Vessel Occlusion |
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| Completed | N/A | 348 | RoW | Bailout angioplasty, Standard therapy | Beijing Tiantan Hospital | Acute Ischemic Stroke | 06/23 | 08/23 | | |
NCT04614987: Serum Neurofilament Light (NfL) as a Marker for Brain Injury in Individuals Undergoing Chimeric Antigen Receptor-modified T Therapy |
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| Terminated | N/A | 17 | US | | Washington University School of Medicine, McDonnell Center, Paula and Roger Riney Blood Cancer Research | Neurotoxicity | 09/23 | 09/23 | | |
NCT05556889: Safety and Analgesic Efficacy of a Modified Auriculotemporal Nerve Block |
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| Recruiting | N/A | 252 | RoW | a modified auriculotemporal nerve blockade, Traditional auriculotemporal nerve blockade | Tongji Hospital | Safety and Efficacy, Scalp Nerve Block | 12/24 | 12/24 | | |
| Completed | N/A | 336 | RoW | Esketamine, Es group, Normal saline, Ns group | Ailin Luo, Maternal and Child Health Hospital of Hubei Province, Jingmen No.1 People's Hospital | Esketamine, Postpartum Depression | 03/24 | 03/24 | | |
NCT05972252: First-in-man Study of the Cerebrovascular Interventional Procedural Control System |
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| Recruiting | N/A | 10 | RoW | Cerebrovascular Interventional Procedural Control System | Hangzhou Dinova Neuroscience Technology Co., Ltd | Acute Ischemic Stroke | 12/23 | 03/24 | | |
CSILS, NCT04527861: Oncologic Outcomes of Single-incision Versus Conventional Laparoscopic Surgery for Colorectal Cancer |
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| Recruiting | N/A | 710 | RoW | Single-incision Laparoscopic Surgery, SILS, Conventional Laparoscopic Surgery, CLS | Ruijin Hospital, Dongfang Hospital Affiliated to Tongji University, Fudan University, Changhai Hospital, Shengjing Hospital, RenJi Hospital, Liaoning Cancer Hospital & Institute, Zhejiang Provincial People's Hospital, Shandong Provincial Hospital, The General Hospital of Western Theater Command, Shanghai Jiao Tong University School of Medicine | Colorectal Cancer, Colon Cancer, Rectal Cancer | 04/24 | 04/29 | | |
NCT04703712: Lens Extraction Combined With Goniosynechialysis Versus Trabeculectomy |
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| Recruiting | N/A | 316 | RoW | Lens extraction combined with goniosynechialysis, Trabeculectomy surgery | Eye & ENT Hospital of Fudan University | Glaucoma, Angle-Closure | 12/24 | 12/24 | | |
NCT05352074: STOPS Trial: Total vs Subtotal Colectomy for Slow Transit Constipation |
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| Recruiting | N/A | 202 | RoW | subtotal colectomy with cecal-rectal anastomosis, total colectomy with ileorectal anastomosis | Third Military Medical University | Slow Transit Constipation, Surgery | 12/24 | 12/26 | | |
| Not yet recruiting | N/A | 20 | US | SkinScan3D camera, SS3D | Washington University School of Medicine, National Cancer Institute (NCI), Pensievision | Kaposi Sarcoma | 04/26 | 04/26 | | |
NCT05582551: Patients At Risk for Sensory Screening (HPARSS) to Enhance Sensory Deficit Screening in Childhood Cancer Survivors |
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| Recruiting | N/A | 146 | US | Highlighting Patients at Risk for Sensory Screening (HPARSS) | Washington University School of Medicine, St. Jude Children's Research Hospital | Childhood Cancer | 05/25 | 05/25 | | |
ANGEL-BAO, NCT06101667: Efficacy and Safety of Endovascular Recanalization for Acute Basilar Artery Occlusion With Extended Time Window |
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| Recruiting | N/A | 224 | RoW | Best medical management, Endovascular treatment | Beijing Tiantan Hospital | Acute Ischemic Stroke, Basilar Artery Occlusion | 09/25 | 12/25 | | |
| Recruiting | N/A | 856 | RoW | | Second Affiliated Hospital, School of Medicine, Zhejiang University | Intracerebral Hemorrhage | 12/25 | 12/26 | | |
NCT04995159: Optimized Antiplatelet Therapy in Patients With CHD After Implantation of NeoVasâ„¢ BRS System |
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| Not yet recruiting | N/A | 2150 | RoW | Single anti-platelet therapy, SAPT strategy, Dual anti-platelet therapy, DAPT strategy | Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Heart Disease | 01/26 | 01/28 | | |
NCT05864976: Neurosurgical Neuronavigation Using Resting State MRI and Machine Learning |
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| Recruiting | N/A | 100 | US | Support Vector Machine | Washington University School of Medicine, National Cancer Institute (NCI) | Glioblastoma Multiforme | 01/30 | 01/30 | | |
| Recruiting | N/A | 10000 | RoW | | Second Affiliated Hospital, School of Medicine, Zhejiang University | Intracerebral Hemorrhage | 10/21 | 10/25 | | |
CATCH, NCT05502874: Multicenter Registry for Assessment of Markers of Early Neurological Deterioration in Primary Intracerebral Hemorrhage |
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| Not yet recruiting | N/A | 1600 | RoW | | Second Affiliated Hospital, School of Medicine, Zhejiang University | Intracerebral Hemorrhage, Neurologic Deficits, Hemorrhagic Stroke, Hemorrhage | 12/24 | 10/25 | | |
| Xu, Hongzhi |
NCT04835246: Evaluating Diagnostic Performance of Spectra IMDx System for Detection of Gastric Cancer and Precancerous Lesions |
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| Recruiting | N/A | 185 | RoW | Spectra IMDx system | Endofotonics Pte Ltd, Zhongshan Hospital Xiamen University | Gastric Cancer, Gastric Precancerous Lesion | 05/21 | 07/21 | | |
NCT05637021: Effect of Carbon Dioxide Insufflation and Appendix on the Restoration of Intestinal Microecology After Colonoscopy. |
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| Active, not recruiting | N/A | 38 | RoW | Carbon dioxide insufflated during colonoscopy | Zhongshan Hospital Xiamen University | Colonoscopy, Gastrointestinal Microbiome, Appendix, Carbon Dioxide Insufflation | 07/22 | 12/22 | | |
NCT04989153: Nasal Endoscopic Screening and Risk Assessment for Early Gastric Cancer |
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| Recruiting | N/A | 5000 | RoW | pepsinogen | Second Affiliated Hospital, School of Medicine, Zhejiang University, Jilin City People's Hospital, No. 924 Hospital of the People's Liberation Army of China, Kunshan Hospital of Traditional Chinese Medicine, Chinese PLA General Hospital, Sichuan Provincial People's Hospital, Affiliated Hospital of Southwest Medical University, Zhongshan Hospital Xiamen University, Jingzhou Hospital of Traditional Chinese Medicine, Changhai Hospital | Gastric Cancer, Precancerous Lesion, Helicobacter Pylori Infection | 12/22 | 12/23 | | |
| Xiao, Li |
NCT06010693: A Study of Daridorexant in Chinese Patients With Insomnia Disorder |
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| Completed | 3 | 206 | RoW | Daridorexant, Placebo | Jiangsu Simcere Pharmaceutical Co., Ltd. | Insomnia Disorder | 04/24 | 05/24 | | |
NCT05274191: An Exploratory Basket Study of Pyrotinib Maleate Tablets in HER2 Mutated or Amplified of Metastatic Solid Tumors |
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| Not yet recruiting | 2 | 60 | NA | Pyrotinib Maleate, standard regimen | Zhongshan Hospital Xiamen University | Solid Tumor | 03/22 | 03/24 | | |
NCT04590625: Apatinib Combined With Abraxane and Carboplatin or Cisplatinum as First-line Treatment for Epithelial Ovarian Cancer |
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| Recruiting | 2 | 58 | RoW | Apatinib Mesylate, Abraxane, Cis Platinum, Carboplatin | Zhongshan Hospital Xiamen University | Ovarian Cancer | 10/22 | 12/23 | | |
NCT05441254: Camrelizumab Combined With Intraperitoneal Infusion of Nab-paclitaxel, Intravenous Chemotherapy and S-1 in the Treatment of Advanced Gastric Cancer With Peritoneal Metastasis：Single-arm, Prospective Clinical Study |
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| Not yet recruiting | 2 | 33 | NA | Camrelizumab; Nab-paclitaxel; S-1, Arm PD-1 | Zhongshan Hospital Xiamen University, Jiangsu Hengrui Pharmaceutical Co., Ltd. | Stage IV Gastric Cancer With Metastasis | 06/23 | 12/23 | | |
| Heringh, Zsanett |
| Recruiting | 3 | 612 | Europe, Canada, US, RoW | ABX464, Obefazimod, Placebo | Abivax S.A. | Ulcerative Colitis | 03/25 | 04/25 | | |
LUCENT-URGE, NCT05767021: A Study of Mirikizumab (LY3074828) in Participants With Moderately to Severely Active Ulcerative Colitis |
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| Active, not recruiting | 3 | 160 | Europe, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Ulcerative Colitis, Ulcerative Colitis Chronic | 08/24 | 09/25 | | |
| Recruiting | 3 | 778 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Crohn's Disease | 11/24 | 12/26 | | |
| Recruiting | 3 | 1050 | Europe, Canada, Japan, US, RoW | ABX464, Obefazimod, Placebo | Abivax S.A. | Ulcerative Colitis | 01/26 | 01/30 | | |
| Fan, Yanyun |
NCT06233461: A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease |
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| Recruiting | 2 | 268 | Europe, Canada, Japan, US, RoW | TAK-279, Zasocitinib, Placebo | Takeda | Crohn's Disease | 09/26 | 07/27 | | |
NCT04521205: A Multicenter Clinical Trial: Efficacy, Safety of Fecal Microbiota Transplantation for Inflammatory Bowel Disease |
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| Recruiting | 1 | 200 | RoW | fecal microbiota capsule | Zhongshan Hospital Xiamen University | Inflammatory Bowel Disease, Ulcerative Colitis Type | 12/23 | 04/24 | | |
NCT03426683: The Effect of Intestinal Microbiota Transplantation for Inflammatory Bowel Diseases |
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| Completed | N/A | 35 | RoW | Intestinal Microbiota Transplantation | Zhongshan Hospital Xiamen University | Inflammatory Bowel Disease(IBD) | 10/21 | 12/22 | | |
| Cai, Shuntian |
NCT04590625: Apatinib Combined With Abraxane and Carboplatin or Cisplatinum as First-line Treatment for Epithelial Ovarian Cancer |
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| Recruiting | 2 | 58 | RoW | Apatinib Mesylate, Abraxane, Cis Platinum, Carboplatin | Zhongshan Hospital Xiamen University | Ovarian Cancer | 10/22 | 12/23 | | |
| Kyrychenko, Olga |
| Recruiting | 3 | 778 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Crohn's Disease | 11/24 | 12/26 | | |
| Duan, Hongbing |
NCT04848753: Perioperative Toripalimab (JS001) Combined With Neoadjuvant Chemotherapy in Patients With Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma |
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| Active, not recruiting | 3 | 663 | RoW | Toripalimab combined with cisplatin and paclitaxel, Placebo combined with cisplatin and paclitaxel | Shanghai Junshi Bioscience Co., Ltd. | Resectable Locally Advanced Thoracic Esophageal Squamous Cell Carcinoma | 05/27 | 05/27 | | |
| Xue, Yuan |
NCT05247216: A Phase 2 Study of Hemay007 in Patients With Rheumatoid Arthritis |
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| Completed | 2 | 140 | RoW | Hemay007 800 mg QD group, Hemay007 1200 mg QD group, Hemay007 600 mg QD group, Hemay007 placebo group | Tianjin Hemay Pharmaceutical Co., Ltd | Rheumatoid Arthritis | 06/23 | 06/23 | | |
NCT06250062: A Clinical Study of JS005 in Patients With Ankylosing Spondylitis |
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| Recruiting | 2 | 261 | RoW | Recombinant humanized IL-17A Monoclonal Antibody（JS005）, Placebo（JS005） | Shanghai Junshi Bioscience Co., Ltd., Sponsor GmbH | Ankylosing Spondylitis | 02/25 | 10/25 | | |
| Ishigami, Keisuke |
| Recruiting | 3 | 778 | Europe, Canada, Japan, US, RoW | Mirikizumab, LY3074828 | Eli Lilly and Company | Crohn's Disease | 11/24 | 12/26 | | |
| Li, Xiuji |
| Recruiting | N/A | 10254 | RoW | | Limeng Chen | Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder | 12/24 | 12/24 | | |
| Guan, Tianjun |
| Recruiting | 2 | 140 | RoW | WS016 3g, WS016 6g, WS016 12g, Matching Placebo | Waterstone Pharmaceutical (Wuhan) Co., LTD. | Hyperkalemia | 04/24 | 08/24 | | |
| Recruiting | N/A | 10254 | RoW | | Limeng Chen | Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder | 12/24 | 12/24 | | |
| Guo, Xiaodan |
| Recruiting | N/A | 10254 | RoW | | Limeng Chen | Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder | 12/24 | 12/24 | | |
