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 59 Trials 
168 Trials

   

 
Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Levine, John
NCT05090384: Pediatric GVHD Low Risk Steroid Taper Trial

Recruiting
2
50
Canada, US
Prednisone
John Levine
Acute Graft vs Host Disease, Allogeneic Bone Marrow Transplantation, Adverse Effects
03/25
03/25
NCT02843347: STRIDE Biorepository

Recruiting
N/A
200
US
Blood draw
Emory University, National Heart, Lung, and Blood Institute (NHLBI)
Anemia, Sickle Cell
07/23
07/23
Hutchinson, Raymond J
NCT02879643: Vincristine Sulfate Liposome Injection (Marqibo®) in Combination With UK ALL R3 Induction Chemotherapy for Children, Adolescents, and Young Adults With Relapsed ALL

Recruiting
1
36
Canada, US, RoW
Marqibo
Therapeutic Advances in Childhood Leukemia Consortium, Spectrum Pharmaceuticals, Inc
ALL, Childhood, Lymphoblastic Leukemia, Acute, Childhood, Lymphoblastic Leukemia, Acute
08/21
12/22
NCT01120353: Childhood Cancer Survivor Study

Recruiting
N/A
50000
Canada, US
St. Jude Children's Research Hospital, National Cancer Institute (NCI), Fred Hutchinson Cancer Center, Nationwide Children's Hospital, M.D. Anderson Cancer Center, University of Southern California, Children's Hospital Medical Center, Cincinnati, University of California, San Francisco
Cancer
11/26
11/26
Miller, Bruce L
MOONSI, NCT02075775: MOON Shoulder Instability-Cohort of Patients Undergoing Operative Treatment.

Recruiting
N/A
2500
US
Carolyn M Hettrich, University of Michigan, University of California, San Francisco, University of Kentucky, Hospital for Special Surgery, New York, University of Colorado, Denver, Ohio State University, Washington University School of Medicine, Orthopedic Institute, Sioux Falls, SD, Vanderbilt University, Brigham and Women's Hospital
Other Instability, Shoulder, Dislocations, Subluxations, Recurrent Dislocation of Shoulder Region
12/22
12/42
ARC, NCT03295994: Operative Versus Non-Operative Treatment for Atraumatic Rotator Cuff Tears

Active, not recruiting
N/A
189
US
Operative, Non-Operative
University of Michigan, Patient-Centered Outcomes Research Institute, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Rotator Cuff Tear
02/25
11/26
NCT03511586: Total Shoulder Arthroplasty Multi-Center Registry

Recruiting
N/A
2500
Europe, US
Arthrex, Inc.
Shoulder Arthroplasty
07/25
11/27
Hyzy, Robert C
ACTIV-4, NCT04505774 / 2020-004285-19: Accelerating COVID-19 Therapeutic Interventions and Vaccines 4 ACUTE

Completed
4
3591
Europe, US, RoW
theraputic heparin, unfractionated heparin, Enoxaparin, Dalteparin, Tinzaparin, Heparin, prophylactic heparin, enoxaparin, dalteparin, Fondparinux, P2Y12, Ticagrelor, Prasugrel, Clopidogrel, Crizanlizumab Injection, SGLT2 inhibitor, dapagliflozin, empagliflozin, canagliflozin, ertugliflozin
Matthew Neal MD, National Heart, Lung, and Blood Institute (NHLBI)
Covid19
08/23
01/24
NCT05354141: Extracellular Vesicle Treatment for Acute Respiratory Distress Syndrome (ARDS) (EXTINGUISH ARDS)

Recruiting
3
970
US
ExoFlo, Intravenous normal saline
Direct Biologics, LLC
Acute Respiratory Distress Syndrome, ARDS
03/25
08/25
REMAP-CAP, NCT02735707 / 2015-002340-14: Randomized, Embedded, Multifactorial Adaptive Platform Trial for Community- Acquired Pneumonia

Recruiting
3
20000
Europe, Canada, Japan, US, RoW
Ceftriaxone, Moxifloxacin or Levofloxacin, Piperacillin-tazobactam, Ceftaroline, Amoxicillin-clavulanate, Standard course macrolide, Extended course macrolide, No systemic corticosteroid, Fixed-duration Hydrocortisone, Shock-dependent hydrocortisone, Fixed-duration higher dose Hydrocortisone, No antiviral agent for influenza, Five-days oseltamivir, Ten-days oseltamivir, No antiviral agent for COVID-19, Lopinavir / Ritonavir, Hydroxychloroquine, Hydroxychloroquine + lopinavir/ritonavir, Ivermectin, No immune modulation for COVID-19, Interferon beta-1a, IFN-β1a, Anakinra, Tocilizumab, Sarilumab, Local standard venous thromboprophylaxis, Therapeutic dose anticoagulation, Conventional low dose thromboprophylaxis, Intermediate dose thromboprophylaxis, Continuation of therapeutic dose anticoagulation, No immunoglobulin, Convalescent plasma, Delayed administration of convalescent plasma, No vitamin C, Vitamin C, No antiplatelet, Aspirin, acetylsalicylic acid, P2Y12 inhibitor, Clopidogrel, Prasugrel, Ticagrelor, No simvastatin, Simvastatin, Eritoran, Apremilast, Clinician-preferred mechanical ventilation strategy, Protocolised mechanical ventilation strategy, No renin-angiotensin system inhibitor, Angiotensin converting enzyme inhibitor, Ramipril, Lisinopril, Perindopril, Enalapril, Trandolapril, Captopril, Angiotensin Receptor Blockers, Losartan, Valsartan, Candesartan, Irbesartan, Telmisartan, Olmesartan, ARB + DMX-200, No cysteamine, Cysteamine, Fixed-duration dexamethasone, Baloxavir Marboxil, Five-days oseltamivir + baloxavir marboxil, Ten-days oseltamivir + baloxavir marboxil, No endothelial modulator, Imatinib, No Immune Modulator for Influenza, Baricitinib, Nirmatrelvir/ritonavir, Paxlovid, Remdesivir, Nirmatrelvir/ritonavir + remdesivir
UMC Utrecht, Australian and New Zealand Intensive Care Research Centre, Medical Research Institute of New Zealand, Unity Health, Berry Consultants, Global Coalition for Adaptive Research, University of Pittsburgh Medical Center, Intensive Care National Audit & Research Centre, St. Marianna University School of Medicine, Nat Intensive Care Surveillance - MORU, National University Hospital, Singapore
Community-acquired Pneumonia, Influenza, COVID-19
02/26
02/28
GRAIL^3, NCT04706507: Ganciclovir to Prevent Reactivation of Cytomegalovirus in Patients With Acute Respiratory Failure and Sepsis

Active, not recruiting
3
500
US
IV Ganciclovir, Cytovene
Fred Hutchinson Cancer Center, National Heart, Lung, and Blood Institute (NHLBI)
Acute Respiratory Failure
10/24
08/27
NCT06521502: The APS Phenotyping Study

Recruiting
N/A
4000
US
Blood collection, Urine Collection, Nasal, oral, and rectal swabs, Stool collection, Heat Moisture Exchange Filter collection, Tracheal Aspirate sample collection, Non-bronchoscopic bronchoalveolar lavage (NBBAL), Surveys, Short physical performance battery, Hand grip strength, CNS Vital Signs, Muscle Ultrasound, Muscle Strength, Spirometry, Lung Diffusion Testing (DLCO), Chest CT Scan
Vanderbilt University Medical Center
ARDS, Sepsis, Pneumonia
04/28
04/28
Kitko, Carrie
NCT05457556: Mismatched Related Donor Versus Matched Unrelated Donor Stem Cell Transplantation for Children, Adolescents, and Young Adults With Acute Leukemia or Myelodysplastic Syndrome

Recruiting
3
435
Canada, US, RoW
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Marrow Aspiration, Busulfan, 1, 4-Bis[methanesulfonoxy]butane, BUS, Busilvex, Bussulfam, Busulfanum, Busulfex, Busulphan, CB 2041, CB-2041, Glyzophrol, GT 41, GT-41, Joacamine, Methanesulfonic Acid Tetramethylene Ester, Methanesulfonic acid, tetramethylene ester, Mielucin, Misulban, Misulfan, Mitosan, Myeleukon, Myeloleukon, Myelosan, Mylecytan, Myleran, Sulfabutin, Tetramethylene Bis(methanesulfonate), Tetramethylene bis[methanesulfonate], WR-19508, Cyclophosphamide, (-)-Cyclophosphamide, 2H-1,3,2-Oxazaphosphorine, 2-[bis(2-chloroethyl)amino]tetrahydro-, 2-oxide, monohydrate, Asta B 518, B 518, B-518, B518, Carloxan, Ciclofosfamida, Ciclofosfamide, Cicloxal, Clafen, Claphene, CP monohydrate, CTX, CYCLO-cell, Cycloblastin, Cycloblastine, Cyclophospham, Cyclophosphamid monohydrate, Cyclophosphamide Monohydrate, Cyclophosphamidum, Cyclophosphan, Cyclophosphane, Cyclophosphanum, Cyclostin, Cyclostine, Cytophosphan, Cytophosphane, Cytoxan, Fosfaseron, Genoxal, Genuxal, Ledoxina, Mitoxan, Neosar, Revimmune, Syklofosfamid, WR 138719, WR- 138719, WR-138719, WR138719, Echocardiography, EC, Fludarabine, Fluradosa, Haploidentical Hematopoietic Cell Transplantation, Haploidentical Stem Cell Transplantation, HLA-Haploidentical Hematopoietic Cell Transplantation, Stem Cell Transplantation, Haploidentical, Lapine T-Lymphocyte Immune Globulin, Anti-Thymocyte Globulin Rabbit, Antithymocyte Globulin Rabbit, Antithymocyte globulin rabbit ATG, Grafalon, Imtix, Rabbit Anti-Human Thymocyte Globulin (RATG), Rabbit Anti-Thymocyte Globulin, Rabbit Antithymocyte Globulin, Rabbit ATG, Thymoglobulin, Lumbar Puncture, LP, Spinal Tap, Matched Unrelated Donor Hematopoietic Cell Transplantation, MUD-HCT, Melphalan, Alanine Nitrogen Mustard, CB-3025, L-PAM, L-Phenylalanine Mustard, L-Sarcolysin, L-Sarcolysin Phenylalanine mustard, L-Sarcolysine, Melphalan for Injection-Hepatic Delivery System, Melphalanum, Phenylalanine Mustard, Phenylalanine Nitrogen Mustard, Sarcoclorin, Sarkolysin, WR-19813, Methotrexate, Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, CL 14377, CL-14377, Emtexate, Emthexat, Emthexate, Farmitrexat, Fauldexato, Folex, Folex PFS, Lantarel, Ledertrexate, Lumexon, Maxtrex, Medsatrexate, Metex, Methoblastin, Methotrexate LPF, Methotrexate Methylaminopterin, Methotrexatum, Metotrexato, Metrotex, Mexate, Mexate-AQ, MTX, Novatrex, Rheumatrex, Texate, Tremetex, Trexeron, Trixilem, WR-19039, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Mycophenolate Mofetil, CellCept, MMF, Myeloablative Conditioning, Myeloablation, Myeloablative, Myeloablative Cytoreduction, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Rituximab, ABP 798, BI 695500, BI-695500, BI695500, Blitzima, C2B8 Monoclonal Antibody, Chimeric Anti-CD20 Antibody, CT-P10, IDEC 102, IDEC-102, IDEC-C2B8, IDEC-C2B8 Monoclonal Antibody, IDEC102, Ikgdar, Mabtas, MabThera, Monoclonal Antibody IDEC-C2B8, PF 05280586, PF-05280586, PF05280586, Riabni, Ritemvia, Rituxan, Rituximab ABBS, Rituximab ARRX, Rituximab Biosimilar ABP 798, Rituximab Biosimilar BI 695500, Rituximab Biosimilar CT-P10, Rituximab Biosimilar GB241, Rituximab Biosimilar IBI301, Rituximab Biosimilar JHL1101, Rituximab Biosimilar PF-05280586, Rituximab Biosimilar RTXM83, Rituximab Biosimilar SAIT101, Rituximab Biosimilar SIBP-02, rituximab biosimilar TQB2303, Rituximab PVVR, Rituximab-abbs, Rituximab-arrx, Rituximab-blit, Rituximab-pvvr, Rituximab-rite, Rituximab-rixa, Rituximab-rixi, Rixathon, Riximyo, RTXM 83, RTXM-83, RTXM83, Ruxience, Truxima, T-Cell Depletion Therapy, T-Cell Depletion, T-Lymphocyte Depletion Therapy, Tacrolimus, FK 506, FK-506, FK506, Fujimycin, Hecoria, Prograf, Protopic, Tacforius, Thiotepa, 1,1',1''-Phosphinothioylidynetrisaziridine, Girostan, N,N', N''-Triethylenethiophosphoramide, Oncotiotepa, SH 105, SH-105, SH105, STEPA, Tepadina, Tepylute, TESPA, Tespamin, Tespamine, Thio-Tepa, Thiofosfamide, Thiofozil, Thiophosphamide, Thiophosphoamide, Thiophosphoramide, Thiotef, Tifosyl, TIO TEF, Tio-tef, Triethylene Thiophosphoramide, Triethylenethiophosphoramide, Tris(1-aziridinyl)phosphine sulfide, TSPA, WR 45312, Total-Body Irradiation, SCT_TBI, TBI, Total Body Irradiation, Whole Body, Whole Body Irradiation, Whole-Body Irradiation
Children's Oncology Group
Acute Lymphoblastic Leukemia, Acute Myeloid Leukemia, Mixed Phenotype Acute Leukemia, Myelodysplastic Syndrome
12/27
12/27
NCT04198922: Acalabrutinib for the Treatment of Chronic Graft Versus Host Disease

Recruiting
2
50
US
Acalabrutinib, 1420477-60-6, ACP-196, Benzamide, Bruton Tyrosine Kinase Inhibitor ACP-196, Questionnaire Administration
Fred Hutchinson Cancer Center, AstraZeneca
Recurrent Moderate-Severe Chronic Graft Versus Host Disease, Hematopoietic and Lymphoid Cell Neoplasm
12/25
01/27
NCT05090384: Pediatric GVHD Low Risk Steroid Taper Trial

Recruiting
2
50
Canada, US
Prednisone
John Levine
Acute Graft vs Host Disease, Allogeneic Bone Marrow Transplantation, Adverse Effects
03/25
03/25
ROCKstar, NCT03640481: Efficacy and Safety of KD025 in Subjects With cGVHD After At Least 2 Prior Lines of Systemic Therapy

Checkmark Pivotal data from ROCKstar trial in cGVHD
Jul 2021 - Jul 2021: Pivotal data from ROCKstar trial in cGVHD
Checkmark Follow-up analysis data from ROCKstar trial for cGVHD at EHA 2021
Jun 2021 - Jun 2021: Follow-up analysis data from ROCKstar trial for cGVHD at EHA 2021
Checkmark Follow-up data from ROCKstar trial for cGVHD at ASH
More
Terminated
2
159
US
Belumosudil (KD025), REZUROCK
Kadmon, a Sanofi Company
Chronic Graft-versus-host-disease
12/23
12/23
CASSIOPEIA, NCT03876769 / 2017-002116-14: Study of Efficacy and Safety of Tisagenlecleucel in HR B-ALL EOC MRD Positive Patients

Calendar Jan 2025 - Dec 2025: Data from CASSIOPEIA trial for 1L acute ALL
Active, not recruiting
2
121
Europe, Canada, US
CTL019
Novartis Pharmaceuticals, Children's Oncology Group
B-Cell Acute Lymphoblastic Leukemia
10/27
10/27
NCT03842696: Vorinostat for Graft vs Host Disease Prevention in Children, Adolescents and Young Adults Undergoing Allogeneic Blood and Marrow Transplantation

Recruiting
1/2
49
US
Vorinostat, Blood and Marrow Transplant (BMT), Tacrolimus (or cyclosporine), Methotrexate, Mycophenolate Mofetil (MMF), Cyclophosphamide
University of Michigan Rogel Cancer Center, National Institutes of Health (NIH), National Center for Advancing Translational Sciences (NCATS)
Hematologic Diseases, Acute Leukemia in Remission, Chronic Myelogenous Leukemia - Chronic Phase, Chronic Myelogenous Leukemia, Accelerated Phase, Chronic Myelogenous Leukemia, Blastic Phase, Myelodysplastic Syndromes, Mantle Cell Lymphoma, Follicular Lymphoma, Diffuse Large B Cell Lymphoma, Non Hodgkin Lymphoma, Graft Vs Host Disease, Graft-versus-host-disease
06/25
06/26
NCT01590680: Expanded Access Protocol Using 131I-MIBG

Available
N/A
US
I-131 MIBG, I-131 Iobenguane, I-131 meta-iodobenzylguanidine
Jubilant DraxImage Inc.
Neuroblastoma, Pheochromocytoma, Paraganglioma
 
 
NCT04372524: Biomarker Verification in Pediatric Chronic GvHD: ABLE 2.0 / PTCTC GVH 1901 Study

Recruiting
N/A
350
Canada, US
University of British Columbia
Chronic Graft-versus-Host-Disease, Leukemia, Allogeneic Hematopoietic Stem Cell Transplantation, Blood Cancer, Non-Malignant Hematologic and Lymphocytic Disorder
01/24
01/25
NCT03718546: Identifying Predictors of Poor Health-Related Quality-of-Life Among Pediatric Hematopoietic Stem Cell Donors

Active, not recruiting
N/A
754
US
Center for International Blood and Marrow Transplant Research, University of Pittsburgh
Quality of Life
08/24
08/24
CATCH, NCT04188912: Close Assessment and Testing for Chronic Graft Versus Host Disease, Study

Active, not recruiting
N/A
273
US
Biospecimen Collection, Optical Coherence Tomography, OCT, Spirometry, Survey Administration, Digital Photography, Quality-of-Life Assessment, Quality of Life Assessment, Medical Chart Review, Chart Review
Fred Hutchinson Cancer Center, National Cancer Institute (NCI), National Institutes of Health (NIH)
Hematopoietic and Lymphoid Cell Neoplasm
10/25
10/25
Khanna, Dinesh
NCT05000216: COVID-19 Booster Vaccine in Autoimmune Disease Non-Responders

Completed
2
257
US
Moderna mRNA-1273, mRNA-1273 vaccine (Moderna), Moderna COVID-19 Vaccine, SARS-CoV-2 RNA vaccine, COVID-19 vaccine, BNT162b2, mRNA-1273 vaccine (Pfizer/BioNTech), Pfizer-BioNTech COVID-19 vaccine, Ad26.COV2.S, Janssen COVID-19 Vaccine, JNJ-78436735, Continue IS (MMF or MPA), immunosuppressive medication, mycophenolate mofetil, MMF, CellCept®, mycophenolic acid, MPA, Continue IS (MTX), methotrexate, MTX, Continue IS (B cell depletion therapy), mAbs targeting CD19 or CD20, anti-BAFF mAb, Monovalent [B.1.351] CoV2 preS dTM-AS03, Sanofi-GSK COVID-19 Vaccine, Withhold IS (MMF or MPA), Withhold IS (MTX), Withhold IS (B cell depletion therapy), Moderna mRNA-1273, Bivalent, mRNA-1273 vaccine (Moderna), Bivalent, Moderna COVID-19 Vaccine, Bivalent, SARS-CoV-2 RNA vaccine, Bivalent, COVID-19 vaccine, Bivalent, BNT162b2, Bivalent, mRNA-1273 vaccine (Pfizer/BioNTech), Bivalent, Pfizer-BioNTech COVID-19 vaccine, Bivalent
National Institute of Allergy and Infectious Diseases (NIAID), Autoimmunity Centers of Excellence, Rho Federal Systems Division, Inc.
Rheumatoid Arthritis (RA), Systemic Lupus Erythematosus (SLE), Pemphigus Vulgaris, Multiple Sclerosis (MS), Systemic Sclerosis (SSc), Pediatric SLE, Juvenile Idiopathic Arthritis (JIA), Juvenile Dermatomyositis (JDM), Pediatric-Onset Multiple Sclerosis (POMS)
06/23
03/24
CONQUEST, NCT06195072: Platform Clinical Study for Conquering Scleroderma

Recruiting
2
400
US
Amlitelimab, BI 1015550, Placebo
Scleroderma Research Foundation, Inc., Sanofi, Boehringer Ingelheim
Interstitial Lung Disease Due to Systemic Disease, Scleroderma
11/26
11/26
BRAVOS, NCT03222492: Brentuximab Vedotin for Systemic Sclerosis

Completed
1/2
17
US
Brentuximab Vedotin, Adcetris®, Placebo, Placebo for brentuximab vedotin
National Institute of Allergy and Infectious Diseases (NIAID), Immune Tolerance Network (ITN), Seagen Inc., PPD, Rho Federal Systems Division, Inc.
Diffuse Cutaneous Systemic Sclerosis, Scleroderma, dcSSc
04/23
04/23
NCT05026853: Patient-Reported Outcomes Measurement Information System Integration Into Rheumatology Clinical Practice

Completed
N/A
110
US
PRO Integration into Clinical Practice
University of Michigan, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS)
Rheumatic Diseases
02/23
05/23
Smith, Yolanda R
NCT05144386: Study of EBT-101 in Aviremic HIV-1 Infected Adults on Stable ART

Completed
1
6
US
EBT-101
Excision BioTherapeutics
HIV-1-infection
11/24
11/24
Burgess, Helen
NCT04117347: Morning Light Treatment for Traumatic Stress: The Role of Amygdala Reactivity

Completed
N/A
50
US
Light therapy A via the Re-Timer®, Re-Timer®, Light therapy B via the Re-Timer®, Light therapy C via the Re-Timer®
University of Michigan, National Institute of Mental Health (NIMH)
Stress
03/23
03/23
NCT06567886: Fibromyalgia Sleep A to ZZZ Study

Recruiting
N/A
390
US
Light Therapy, Re-Timer, Sleep Stabilization
University of Michigan, National Institute of Nursing Research (NINR)
Fibromyalgia
03/29
03/29
NCT06094608: IBD-Sleep: A Pilot Study Looking at Changes in Sleep Timing and IBD Symptoms

Recruiting
N/A
68
US
Morning light treatment, Re-Timer®, Treatment-as-usual
University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Inflammatory Bowel Diseases, Ulcerative Colitis, Crohn Disease
05/26
05/26
O'Brien, Louise M
NCT06614582: Long-term Evaluation of Nasopharyngeal Airway in Hypotonia

Enrolling by invitation
N/A
40
US
Self-Supporting Nasopharyngeal Airway (ssNPA)
University of Michigan
Hypotonia, Muscle, Obstructive Sleep Apnea, Nasal Airway Obstruction
10/26
10/26
NCT04205370: Sleep Behaviors in Pregnancy

Recruiting
N/A
500
US
Deactivated Pregnancy Coach, Active Pregnancy Coach
University of Michigan
Sleep, Pregnancy Complications
12/26
12/26
NCT05527652: Self-Supporting Nasopharyngeal Airway (ssNPA) Treating Upper Airway Obstruction in Hypotonia

Recruiting
N/A
40
US
Self-Supporting Nasopharyngeal Airway (ssNPA)
University of Michigan, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI)
Obstructive Sleep Apnea, Hypertonia, Muscle, Nasal Airway Obstruction, Tolerance, Trisomy 21, Down Syndrome
08/26
08/26
McLaughlin, Vallerie
IMPAHCT-FUL, NCT05557942 / 2021-006864-25: Inhaled Imatinib Pulmonary Arterial Hypertension Clinical Trial - Follow Up Long Term Extension

Terminated
3
186
Europe, Canada, US, RoW
AV-101
Aerovate Therapeutics, Aerovate Therapeutics Inc
Pulmonary Arterial Hypertension
08/24
08/24
IMPAHCT, NCT05036135 / 2021-001910-13: A Study of AV-101 (Dry Powder Inhaled Imatinib) in Patients With Pulmonary Arterial Hypertension (PAH)

Terminated
2/3
202
Europe, Canada, US, RoW
AV-101, Placebo
Aerovate Therapeutics, Aerovate Therapeutics, Inc.
Pulmonary Arterial Hypertension
08/24
08/24
ELEVATE 2, NCT04712669 / 2020-004971-42: A Study of Rodatristat Ethyl in Patients With Pulmonary Arterial Hypertension

Completed
2
108
Europe, Canada, US, RoW
rodatristat ethyl 300 mg tablet BID, rodatristat ethyl 600 mg BID, Placebo
Altavant Sciences GmbH
Pulmonary Arterial Hypertension
06/23
08/23
PaRTAkE-PH, NCT04254289: Pilot Randomized Trial of Ambulatory Exercise in Pulmonary Hypertension

Withdrawn
N/A
54
US
Usual Care, Home-based exercise program
University of Michigan, Actelion
Pulmonary Arterial Hypertension
06/25
12/25
Pitt, Bertram
SPIRRIT, NCT02901184 / 2016-002019-16: Spironolactone Initiation Registry Randomized Interventional Trial in Heart Failure With Preserved Ejection Fraction

Recruiting
3
2000
Europe, US
Spironolactone, Standard care
Uppsala University, Karolinska University, Duke Clinical Research Institute, National Heart, Lung, and Blood Institute (NHLBI)
Heart Failure With Preserved Ejection Fraction
12/26
12/26
Pipe, Steve
PRESent-5, NCT05605678: Hemophilia Non-Interventional Study Prior to SerpinPC Intervention

Recruiting
N/A
200
Europe, Canada, US, RoW
No Intervention
ApcinteX Ltd, Centessa Pharmaceuticals plc
Hemophilia A, Hemophilia B
11/24
11/24
Arnedt, J Todd
NCT04457674: Targeting Sleep Homeostasis to Improve Alcohol Use Disorder Treatment Outcomes (M-STAR Study)

Recruiting
N/A
150
US
Cognitive Behavioral Therapy for insomnia (CBTi), Sleep Hygiene Education (SHE)
University of Michigan, National Institute on Alcohol Abuse and Alcoholism (NIAAA)
Insomnia, Alcohol Use Disorder
08/25
08/25
Napolitano, Lena M
NCT05057221: Safety, Tolerability and Efficacy of Uproleselan (GMI-1271) in Patients With COVID-19 Pneumonia

Terminated
1/2
6
US
Uproleselan
Lena Napolitano, MD, GlycoMimetics Incorporated
COVID-19 Pneumonia
03/22
03/22
MIRO-01-001, NCT06285253: MiroliverELAP® for the Treatment of Acute Liver Failure: a Phase 1 Trial

Recruiting
1
15
US
miroliverELAP treatment
Miromatrix Medical Inc.
Acute Liver Failure, Acute Liver Injury, Drug Induced
01/25
02/25
Alam, Hasan
NCT06062888: FFP in Traumatic BRAin INjury (FIT-BRAIN) Trial

Not yet recruiting
2/3
357
NA
Fresh Frozen Plasma (FFP)
Northwestern University, Vanderbilt University Medical Center, University of Southern California, Oregon Health and Science University, Medical College of Wisconsin, University of Texas Southwestern Medical Center, University of California, Davis, University of Alabama at Birmingham
Moderate to Severe Traumatic Brain Injury
02/28
09/28
TRIAD, NCT05887414: Appendicitis Decision-making Surveys

Recruiting
N/A
3000
US
Baseline, 30 Day Follow Up
University of Washington, Patient-Centered Outcomes Research Institute
Appendicitis
10/24
10/25
Lumeng, Julie C
NCT04114123: The Development of Reward Response to Food in Infancy

Completed
N/A
1166
US
University of Michigan, American Heart Association
Eating Behavior
06/24
06/24
NCT06358729: Pre-Pregnancy Weight Loss and Baby Behavior Study

Not yet recruiting
N/A
30
US
Typical Nipple, Challenging Nipple
University of Michigan
Obesity; Familial, Pregnancy Related, Infant Behavior
04/27
04/27
NCT04723264: The Development of Eating Behavior in Infancy: Associations With Behavior, Diet, and Growth at School Age

Recruiting
N/A
400
US
Food protocols
University of Michigan, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Eating Behavior
07/26
07/26
NCT06039878: Mother-Baby Study - Observational

Recruiting
N/A
240
US
Bonding-Evoked Oxytocin, Distress Relieving Effects of Sucrose, Hedonic Response to Sucrose, Typical versus Challenging Feeding-Social, Caloric Compensation-Social, Ability to Delay Gratification for Food in Infants-Social Task (ATDG-FIT-Social)
University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Obesity, Childhood, Obesity
12/27
12/27
NCT06072664: Mother-Baby Study - Caloric Compensation Index (COMPX)

Recruiting
N/A
120
US
Caloric Compensation Index (COMPX)
University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Eating Behavior
01/28
01/28
NCT06072651: Mother-Baby Study - Relative Reinforcing Value (RRV)

Recruiting
N/A
120
US
Relative Reinforcing Value of Food
University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Eating Behavior
01/28
01/28
NCT06072638: Mother-Baby Study - Eating in the Absence of Hunger (EAH)

Recruiting
N/A
120
US
Eating in Absence of Hunger
University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Eating Behavior
01/28
01/28
Lugt, Mark Vander
ACCESS, NCT04904588: HLA-Mismatched Unrelated Donor Hematopoietic Cell Transplantation With Post-Transplantation Cyclophosphamide

Recruiting
2
300
US
Busulfan, Busulfex®, Fludarabine, Fludara®, Total-body irradiation, TBI, Cyclophosphamide, Cytoxan®, Melphalan, PBSC Hematopoietic Stem Cell Transplantation (HSCT), PBSC HSCT, PBSC HCT, PBSC Transplantation, Bone Marrow Hematopoietic Stem Cell Transplantation, BM HSCT, BM HCT, Bone Marrow Transplantation, Post-transplant Cyclophosphamide, Mesna, Mesnex®, Tacrolimus, Mycophenolate Mofetil, MMF, Cellcept®, Patient-Reported Outcomes
Center for International Blood and Marrow Transplant Research, National Marrow Donor Program
Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Mixed Phenotype Acute Leukemia, Acute Leukemia, Myelodysplastic Syndromes, Chronic Myelogenous Leukemia, Chronic Lymphocytic Leukemia, Lymphoma
07/24
07/24
NCT04965597: Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Recruiting
2
40
US
Treosulfan, Dihydroxybusulfan, Ovastat, Treosulphan, Tresulfon, Trecondi, Fludarabine Phosphate, 2-fluoro-9-(5-O-phosphono-.beta.-D-arabinofuranosyl)-, 9H-purin-6-amine, 2-fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl), Beneflur, Fludara, Fludarabine-5'-Monophosphate, SH T 586, Tacrolimus, FK 506, Fujimycin, Hecoria, Prograf, Protopic, Methotrexate, Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, Emthexat, Emtexate, Farmitrexat, Methotrexate LPF, Methylaminopterin, Methotrexatum, Metotrexato, Novatrex, Rheumatrex, Texate, Tremetex, Trexeron, Trixilem, WR-19039, Lapine T-Lymphocyte Immune Globulin, Anti-Thymocyte Globulin Rabbit, Grafalon, Rabbit Anti-Human Thymocyte Globulin (RATG), Rabbit Anti-Thymocyte Globulin, Rabbit Antithymocyte Globulin, Rabbit ATG, rATG, Thymoglobulin, Antithymocyte globulin rabbit ATG, Imtix, Peripheral Blood Stem Cell Transplantation, PBPC transplantation, PBSCT, Peripheral Blood Progenitor Cell Transplantation, PERIPHERAL BLOOD STEM CELL TRANSPLANT, peripheral stem cell support, Peripheral Stem Cell Transplant, peripheral stem cell transplantation, Allogeneic Bone Marrow Transplantation, Allo BMT, Allogeneic Blood and Marrow Transplantation, Allogeneic BMT, Quality-of-Life Assessment, Quality of Life Assessment, Echocardiography, EC, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, Multi-Gated Acquisition Scan, MUGA Scan, Radionuclide Ventriculogram Scan, Radionuclide ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Bone Marrow Biopsy, Bone Marrow Aspiration, Biospecimen Collection, Biological Sample Collection, X-Ray Imaging, Conventional X-Ray, Diagnostic Radiology, Computed Tomography, Computed Axial Tomography, CAT Scan, CT Scan
Fred Hutchinson Cancer Center, Blood and Marrow Transplant Clinical Trials Network, National Cancer Institute (NCI), National Marrow Donor Program, National Heart, Lung, and Blood Institute (NHLBI)
Bone Marrow Failure Syndrome, Congenital Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Hereditary Sideroblastic Anemia, Paroxysmal Nocturnal Hemoglobinuria, Shwachman-Diamond Syndrome, Hematologic Neoplasm With Germline GATA2 Mutation, Hematologic Neoplasm With Germline SAMD9 Mutation, Hematologic Neoplasm With Germline SAMD9L Mutation
12/25
12/26
CSIDE, NCT03619551: Conditioning SCID Infants Diagnosed Early

Recruiting
2
64
Canada, US
Busulfan, Cell processing for TCRαβ+/CD19+ depletion, CliniMACS
Michael Pulsipher, MD
SCID
08/26
08/26
RESKUE, NCT04693598: Gene Transfer Clinical Trial for Krabbe Disease

Active, not recruiting
1/2
6
US
FBX-101, AAVrh.10-hGALC
Forge Biologics, Inc
Krabbe Disease
07/24
07/24
REKLAIM, NCT05739643: Gene Transfer Clinical Trial for Infantile and Late Infantile Krabbe Disease Treated Previously With HSCT

Active, not recruiting
1/2
9
US
FBX-101, AAVrh.10-hGALC
Forge Biologics, Inc
Krabbe Disease
11/26
11/26
NCT03601442: CTL019 Out of Specification MAP for ALL or DLBCL Patients

Available
N/A
Canada, US, RoW
CTL019, tisagenlecleucel, Kymriah
Novartis Pharmaceuticals
Acute Lymphoblastic Leukemia (ALL), Diffuse Large B-cell Lymphoma (DLBCL)
 
 
NCT06308718: Long-term Follow-up Study to Evaluate Safety and Efficacy of FBX-101 in Krabbe Patients

Active, not recruiting
N/A
25
US
FBX-101
Forge Biologics, Inc
Krabbe Disease
11/26
11/26
Richardson, James
NCT05586490: Development of a Multifunctional Rehabilitation Device for Persons With Parkinson's Disease

Completed
N/A
38
US
Multifunctional RehabilitationDevice (MRD), MRD, existing standard rehabilitation device
University of Michigan, National Institute of Neurological Disorders and Stroke (NINDS)
Parkinson Disease
12/23
12/23
COMPLETE-2, NCT05701358: Physiology-guided vs Angiography-guided Non-culprit Lesion Complete Revascularization for Acute MI & Multivessel Disease

Recruiting
N/A
5100
Europe, Canada, US
Physiology-guided NCL PCI, Angiography-guided NCL PCI
Population Health Research Institute
Acute Myocardial Infarction, Coronary Artery Disease
06/28
06/28
Braley, Tiffany J
NCT05269628: Mechanisms of Cannabidiol in Persons With MS: the Role of Sleep and Pain Phenotype

Recruiting
2
166
US
Cannabidiol (CBD), Epidiolex®, Tetrahydrocannabinol (THC), Marinol®, dronabinol, Placebo CBD, Placebo THC
Tiffany J. Braley, MD, MS, National Center for Complementary and Integrative Health (NCCIH)
Multiple Sclerosis, Sleep, Pain
06/26
06/26
TREAT-MS, NCT03500328: Traditional Versus Early Aggressive Therapy for Multiple Sclerosis Trial

Recruiting
N/A
900
US
Natalizumab, Alemtuzumab, Ocrelizumab, Rituximab, Cladribine, Ofatumumab, Ublituximab-xiiy, Tysabri, Lemtrada, Ocrevus, Rituxan, Mavenclad, Kesimpta, Briumvi, Glatiramer acetate, Interferons (intramuscular, subcutaneous, pegylated) Teriflunomide, Fumarates (dimethyl, diroximel, monomethyl) Fingolimod, Siponimod, Ozanimod, Ponesimod, Copaxone, Glatopa, Avonex, Betaseron, Extavia, Rebif, Plegridy, Aubagio, Tecfidera, Vumerity, Bafiertam, Gilenya, Mayzent, Zeposia, Ponvory, Tascenso
Johns Hopkins University, Patient-Centered Outcomes Research Institute, National Multiple Sclerosis Society
Multiple Sclerosis, Relapsing-Remitting
08/25
08/25
Chang, Tammy
NCT05000645: Grocery Delivery and Healthy Weight Gain Among Low-income Pregnant Young Women

Recruiting
N/A
570
US
Grocery delivery, Unsweetened beverage delivery
University of Michigan, Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Pregnancy, Weight Gain
10/26
10/26
Varani, James
NCT03869905: Aquamin® as an Adjuvant Intervention for Ulcerative Colitis

Active, not recruiting
2
40
US
Aquamin®, Nutritional, Placebo first then Aquamin®, Maltodextrin
James Varani
Ulcerative Colitis
04/26
09/26
NCT04855799: GI Permeability Change in Response to Aquamin®

Completed
2
33
US
Aquamin, Nutritional
James Varani
Ulcerative Colitis, Healthy, Irritable Bowel Syndrome With Diarrhea
03/24
03/24
NCT05058638: Effectiveness of Aquamin® in Mitigating Halitosis

Recruiting
2
10
US
Aquamin, Nutritional
University of Michigan
Healthy, Halitosis
07/25
10/25
Nallamothu, Brahmajee K
myBPmyLife, NCT05154929: Improving Blood Pressure Control Through the mHealth Application

Completed
N/A
608
US
Dietary and physical activity JITAI delivered through the myBPmyLife app, Control Group
University of Michigan, American Heart Association
Hypertension
01/24
01/24
NCT05396001: LowSalt4Life: A Mobile Application to Reduce Sodium Intake And Blood Pressure

Recruiting
N/A
400
US
LowSalt4Life Application, Just-In-time Adaptive Intervention (JITAI)
University of Michigan, National Heart, Lung, and Blood Institute (NHLBI)
Hypertension, Blood Pressure
11/25
11/25
MCNAIR, NCT05933083: Study: coMparative effeCtiveness of iN-person and teleheAlth cardIac Rehabilitation

Recruiting
N/A
516
US
In-person cardiac rehabilitation, Telehealth cardiac rehabilitation
University of California, San Francisco, Patient-Centered Outcomes Research Institute, Mayo Clinic, University of Michigan, University of Pittsburgh, Johns Hopkins University
Myocardial Infarction, Heart Failure, Systolic, Heart Valve Diseases, Angina, Stable, Coronary Artery Disease, Heart Transplant
10/26
10/27
Aslam, Muhammad F
VAST-D II, NCT05554627: VA Aripiprazole vs Esketamine for Treatment Resistant Depression

Withdrawn
4
940
US
Esketamine, Spravato (for depression), Ketanest (for anesthesia), Aripiprazole, Abilify, Aristada
VA Office of Research and Development
Depressive Disorder, Major
10/23
10/23
NCT02436707: Novel Combination Therapy in the Treatment of Relapsed and Refractory Aggressive B-Cell Lymphoma

Recruiting
2
320
Canada
Ibrutinib, Rituximab, Gemcitabine, Dexamethasone, Cisplatin, Mesna, Cyclophosphamide, Etoposide, G-CSF, Selinexor
Canadian Cancer Trials Group, Janssen, LP, Roche Pharma AG, Karyopharm Therapeutics Inc
Lymphoma
12/25
12/26
NCT06327152: Caffeine Use in the Management of Preterm Infants

Recruiting
2
40
US
Caffeine, Sterile Water Placebo
University of California, Irvine
Apnea of Prematurity
12/26
12/26
NCT03869905: Aquamin® as an Adjuvant Intervention for Ulcerative Colitis

Active, not recruiting
2
40
US
Aquamin®, Nutritional, Placebo first then Aquamin®, Maltodextrin
James Varani
Ulcerative Colitis
04/26
09/26
NCT04855799: GI Permeability Change in Response to Aquamin®

Completed
2
33
US
Aquamin, Nutritional
James Varani
Ulcerative Colitis, Healthy, Irritable Bowel Syndrome With Diarrhea
03/24
03/24
NCT05058638: Effectiveness of Aquamin® in Mitigating Halitosis

Recruiting
2
10
US
Aquamin, Nutritional
University of Michigan
Healthy, Halitosis
07/25
10/25
NCT04894461: Efficacy of Moxibustion in Diabetes Peripheral Neuropathy

Not yet recruiting
N/A
40
NA
Moxibustion, Moxa stick
Xiamen University
Peripheral Neuropathy, Diabetic Neuropathies
09/23
12/23
Gipson, Debbie
NCT04009668: Tumor Necrosis Factor Inhibition in Focal Segmental Glomerulosclerosis and Treatment Resistant Minimal Change Disease

Completed
2
7
US
adalimumab, Humira
University of Michigan
FSGS, MCD, Focal Segmental Glomerulosclerosis, Minimal Change Disease
09/23
10/23
NEPTUNE, NCT01209000: Nephrotic Syndrome Study Network

Recruiting
N/A
1200
Canada, US
Kidney Biopsy
University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), The NephCure Foundation
Minimal Change Disease (MCD), Membranous Nephropathy, Glomerulosclerosis, Focal Segmental
06/26
06/26
NEPTUNE Match, NCT04571658: Study

Enrolling by invitation
N/A
375
US
Communication
University of Michigan, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Nephrotic Syndrome in Children, Focal Segmental Glomerulosclerosis, Minimal Change Disease, Minimal Change Nephrotic Syndrome, Membranous Nephropathy, FSGS, MCD, MCD - Minimal Change Disease
06/26
06/26
RESOLVE, NCT05650619: Recurrence Post-transplant Observational Study in Focal Segmental Glomerulosclerosis and Minimal Change Disease

Recruiting
N/A
300
US
Biospecimen collection, Data collection
University of Michigan
Focal Segmental Glomerulosclerosis, Minimal Change Disease, FSGS, MCD
12/26
12/26
C-PROBE, NCT01016613: Clinical Phenotyping Resource and Biobank Core of the Michigan O'Brien Renal Center

Recruiting
N/A
1800
US
University of Michigan, St. John Health System, Michigan, Temple University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
Chronic Kidney Disease, Glomerulopathy
07/30
07/30
Prepare-NS, NCT05505500: Interview Study of Adult and Child Patients and Parents of Children with Swelling Due to Nephrotic Syndrome.

Recruiting
N/A
150
US
Interview
University of Michigan, Northwestern University, Food and Drug Administration (FDA)
Fluid Overload, Glomerulosclerosis, Focal Segmental, Edema, Membranous Nephropathy, Minimal Change Disease, Minimal Change Nephrotic Syndrome, IgM Nephropathy, Nephrotic Syndrome, Glomerular Disease, Nephrotic Syndrome, Minimal Change, Nephrotic Syndrome in Children, Nephrotic Syndrome with Edema (Diagnosis), FSGS
04/26
04/26
Fox, Sarah E
NCT06185088: MENDD Tolerance Assessment Study

Terminated
N/A
1
US
Coda® Balloon Catheters, Double Balloon Endoscope (DBE)
University of Michigan
Short Bowel Syndrome
06/23
06/23
Chen, Emily
NCT05156047: A Phase 3 Study to Assess the Safety and Efficacy of Pitolisant in Adult Patients With Idiopathic Hypersomnia

Completed
3
214
US
Open-label pitolisant, Double-blind placebo, Double-blind pitolisant
Harmony Biosciences, LLC
Idiopathic Hypersomnia
09/23
09/23
NCT04698343: Noninvasive Peripheral Nerve Stimulation for Restless Legs Syndrome During Opioid Medication Reduction

Completed
N/A
21
US
Noninvasive Peripheral Nerve Stimulation (NPNS)
Noctrix Health, Inc., National Institute of Neurological Disorders and Stroke (NINDS)
Restless Legs Syndrome
02/23
03/23
Herreshoff, Emily
DOSA, NCT06043440: Oxygen Therapy in Children and Adolescents With Down Syndrome and Obstructive Sleep Apnea

Recruiting
2
230
US
Oxygen
Brigham and Women's Hospital, Children's Hospital Medical Center, Cincinnati, Children's Hospital of Philadelphia, Rainbow Babies and Children's Hospital, University of Michigan, Children's Hospital Los Angeles, Children's Hospital of The King's Daughters, Seattle Children's Hospital, University of Southern California
Down Syndrome, Obstructive Sleep Apnea
08/27
12/27
Hudetz, Anthony G
NCT06403852: Investigating Near-Threshold Perception During Anesthetic Sedation

Recruiting
2
28
US
Functional Magnetic Resonance Imaging (fMRI) with propofol
University of Michigan, National Institute of General Medical Sciences (NIGMS)
Propofol, Anesthesia, fMRI
11/25
12/25
NCT05495945: Ultrasonic Deep Brain Stimulation During Anesthetic Sedation

Recruiting
2
100
NA
Low-intensity focused ultrasound pulsation (LIFUP), Functional Magnetic Resonance Imaging (fMRI) using Propofol, Diprivan
University of Michigan
Mental Function
08/26
08/26
NCT06083493: Neuromodulation of Conscious Perception: Investigating Thalamic Roles Through Ultrasonic Stimulation

Enrolling by invitation
N/A
60
US
LIFUP excitation, LIFUP inhibition
University of Michigan
Thalamus
10/24
10/24
Varner, Connie
PAVO, NCT02445222 / 2014-001673-14: CAR-T Long Term Follow Up (LTFU) Study

Recruiting
3
1400
Europe, Canada, Japan, US, RoW
Previously treated CAR-T patients
Novartis Pharmaceuticals, University of Pennsylvania
Long Term Safety of Patients Receiving CAR-T in an Eligible Clinical Trial or Managed Access Program
02/36
02/36
NCT04965597: Treosulfan-Based Conditioning Regimen Before a Blood or Bone Marrow Transplant for the Treatment of Bone Marrow Failure Diseases (BMT CTN 1904)

Recruiting
2
40
US
Treosulfan, Dihydroxybusulfan, Ovastat, Treosulphan, Tresulfon, Trecondi, Fludarabine Phosphate, 2-fluoro-9-(5-O-phosphono-.beta.-D-arabinofuranosyl)-, 9H-purin-6-amine, 2-fluoro-9-(5-O-phosphono-beta-D-arabinofuranosyl), Beneflur, Fludara, Fludarabine-5'-Monophosphate, SH T 586, Tacrolimus, FK 506, Fujimycin, Hecoria, Prograf, Protopic, Methotrexate, Abitrexate, Alpha-Methopterin, Amethopterin, Brimexate, Emthexat, Emtexate, Farmitrexat, Methotrexate LPF, Methylaminopterin, Methotrexatum, Metotrexato, Novatrex, Rheumatrex, Texate, Tremetex, Trexeron, Trixilem, WR-19039, Lapine T-Lymphocyte Immune Globulin, Anti-Thymocyte Globulin Rabbit, Grafalon, Rabbit Anti-Human Thymocyte Globulin (RATG), Rabbit Anti-Thymocyte Globulin, Rabbit Antithymocyte Globulin, Rabbit ATG, rATG, Thymoglobulin, Antithymocyte globulin rabbit ATG, Imtix, Peripheral Blood Stem Cell Transplantation, PBPC transplantation, PBSCT, Peripheral Blood Progenitor Cell Transplantation, PERIPHERAL BLOOD STEM CELL TRANSPLANT, peripheral stem cell support, Peripheral Stem Cell Transplant, peripheral stem cell transplantation, Allogeneic Bone Marrow Transplantation, Allo BMT, Allogeneic Blood and Marrow Transplantation, Allogeneic BMT, Quality-of-Life Assessment, Quality of Life Assessment, Echocardiography, EC, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, Multi-Gated Acquisition Scan, MUGA Scan, Radionuclide Ventriculogram Scan, Radionuclide ventriculography, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Bone Marrow Biopsy, Bone Marrow Aspiration, Biospecimen Collection, Biological Sample Collection, X-Ray Imaging, Conventional X-Ray, Diagnostic Radiology, Computed Tomography, Computed Axial Tomography, CAT Scan, CT Scan
Fred Hutchinson Cancer Center, Blood and Marrow Transplant Clinical Trials Network, National Cancer Institute (NCI), National Marrow Donor Program, National Heart, Lung, and Blood Institute (NHLBI)
Bone Marrow Failure Syndrome, Congenital Amegakaryocytic Thrombocytopenia, Diamond-Blackfan Anemia, Hereditary Sideroblastic Anemia, Paroxysmal Nocturnal Hemoglobinuria, Shwachman-Diamond Syndrome, Hematologic Neoplasm With Germline GATA2 Mutation, Hematologic Neoplasm With Germline SAMD9 Mutation, Hematologic Neoplasm With Germline SAMD9L Mutation
12/25
12/26
CSIDE, NCT03619551: Conditioning SCID Infants Diagnosed Early

Recruiting
2
64
Canada, US
Busulfan, Cell processing for TCRαβ+/CD19+ depletion, CliniMACS
Michael Pulsipher, MD
SCID
08/26
08/26
RV-BOS, NCT05250037: The Longitudinal Impact of Respiratory Viruses on Bronchiolitis Obliterans Syndrome After Allogeneic Hematopoietic Cell Transplantation (The Study)

Recruiting
N/A
250
US
Home spirometry, SPIROMETRY, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Questionnaire Administration
Fred Hutchinson Cancer Center, National Heart, Lung, and Blood Institute (NHLBI)
Bronchiolitis Obliterans Syndrome, Hematopoietic and Lymphoid Cell Neoplasm
12/27
06/28
Tapper, Elliot
LCN RESCU, NCT05832229: Liver Cirrhosis Network Rosuvastatin Efficacy and Safety for Cirrhosis in the United States

Recruiting
2
256
US
Rosuvastatin, Rosuvastatin 20 mg, Rosuvastatin 10 mg
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), The Cleveland Clinic, Columbia University, Weill Medical College of Cornell University, Duke University, Mayo Clinic, University of Miami, University of Michigan, University of California, San Diego, University of California, San Francisco, LAC+USC Medical Center, Virginia Commonwealth University, National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Cancer Institute (NCI), University of Southern California
Cirrhosis, Cirrhosis, Liver, Cirrhosis Early, Cirrhosis Due to Hepatitis B, Cirrhosis Advanced, Cirrhosis Infectious, Cirrhosis Alcoholic, Cirrhosis Due to Hepatitis C
11/26
11/26
NCT04675775: The BRAINFOOD Trial to Prevent Recurrent Hepatic Encephalopathy.

Completed
N/A
17
US
Medically-tailored meals (MTM), Protein supplements, Nutrition education handout
University of Michigan, National Institute on Aging (NIA)
Cirrhosis, Ascites, Liver Diseases, Frailty, Sarcopenia, Hepatic Encephalopathy
11/22
03/23
RELAX, NCT05457322: The Trial: Nonpharmaceutical Intervention for Nocturnal Muscle Cramps

Completed
N/A
99
US
Behavioral intervention one, Behavioral intervention two
University of Michigan
Cramps, Muscle Cramp
08/23
08/23
NCT06136221: Testing LiverWatch, a Home-Based Remote-Monitoring Intervention for Advanced Liver Disease

Recruiting
N/A
110
US
LiverWatch Intervention
University of Pennsylvania, Pennsylvania Department of Health
Cirrhosis, Liver, End Stage Liver DIsease, Symptoms and Signs, Physical Inactivity, Muscle Loss
05/25
05/26
LCN-C, NCT05740358: Liver Cirrhosis Network Cohort Study

Recruiting
N/A
1200
US
Northwestern University, The Cleveland Clinic, Columbia University, Weill Medical College of Cornell University, Duke University, Mayo Clinic, University of Miami, University of Michigan, University of California, San Diego, University of California, San Francisco, LAC+USC Medical Center, Virginia Commonwealth University, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), National Institute on Alcohol Abuse and Alcoholism (NIAAA), National Cancer Institute (NCI), University of Southern California, Central Virginia Veterans Healthcare System
Cirrhosis, Cirrhosis, Liver, Cirrhosis Early, Cirrhosis Due to Hepatitis B, Cirrhosis Advanced, Cirrhosis Infectious, Cirrhosis Alcoholic, Cirrhosis, Biliary, Cirrhosis Cryptogenic, Cirrhosis Due to Hepatitis C, Cirrhosis Due to Primary Sclerosing Cholangitis
09/27
09/28
Wong, Jane
NCT05057221: Safety, Tolerability and Efficacy of Uproleselan (GMI-1271) in Patients With COVID-19 Pneumonia

Terminated
1/2
6
US
Uproleselan
Lena Napolitano, MD, GlycoMimetics Incorporated
COVID-19 Pneumonia
03/22
03/22
Yessayan, Lenar
SARCA, NCT05339139: SAfety of Regional Citrate Anticoagulation ( Study)

Recruiting
3
50
US
Dialysis
Fresenius Medical Care North America
Acute Kidney Injury, ESRD
11/24
03/25
 

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