| Conway, Charles R |
| Recruiting | N/A | 100 | US | Sham-stimulation, Active-stimulation | Abbott Medical Devices | Treatment Resistant Depression | 04/27 | 04/29 | | |
UNCOVER, NCT04753385: The RECOVER sUb-study, Which Leverages quaNtitative and Credible Research tOols From Verily, Will providE Assessment measuRes for Depressive Episodes |
|
|
| Terminated | N/A | 138 | US | | LivaNova | Treatment Resistant Depression | 09/24 | 09/24 | | |
RECOVER, NCT03887715: A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression |
|
|
| Recruiting | N/A | 6800 | US | Vagus Nerve Stimulation (VNS), VNS | LivaNova | Treatment Resistant Depression | 02/28 | 12/30 | | |
| Lucey, Brendan |
NCT05728736: Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau |
|
|
| Withdrawn | 2 | 30 | US | Lemborexant 25 mg, Dayvigo, Placebo, inactive pill, sugar pil | Brendan Lucey, Eisai Inc. | Alzheimer Disease | 09/23 | 10/23 | | |
| Recruiting | 2 | 201 | US | Lemborexant 10 mg, DAYVIGO, Lemborexant 20mg, Placebo | Washington University School of Medicine, National Institutes of Health (NIH), Eisai Inc., National Institute on Aging (NIA) | Alzheimer Disease | 03/29 | 03/29 | | |
| Recruiting | 2 | 200 | US | Suvorexant 20 mg, Belsomra, Placebo, inactive pill, sugar pill | Washington University School of Medicine, Good Ventures, Merck Sharp & Dohme LLC | Sleep, Alzheimer Disease | 05/26 | 05/26 | | |
| Toedebusch, Cristina |
NCT05728736: Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau |
|
|
| Withdrawn | 2 | 30 | US | Lemborexant 25 mg, Dayvigo, Placebo, inactive pill, sugar pil | Brendan Lucey, Eisai Inc. | Alzheimer Disease | 09/23 | 10/23 | | |
| Recruiting | 2 | 201 | US | Lemborexant 10 mg, DAYVIGO, Lemborexant 20mg, Placebo | Washington University School of Medicine, National Institutes of Health (NIH), Eisai Inc., National Institute on Aging (NIA) | Alzheimer Disease | 03/29 | 03/29 | | |
| Recruiting | 2 | 200 | US | Suvorexant 20 mg, Belsomra, Placebo, inactive pill, sugar pill | Washington University School of Medicine, Good Ventures, Merck Sharp & Dohme LLC | Sleep, Alzheimer Disease | 05/26 | 05/26 | | |
