Conway, Charles R |
| Enrolling by invitation | 1 | 50 | US | Nitrous Oxide, Laughing Gas, Placebo gas | Washington University School of Medicine, American Foundation for Suicide Prevention | Major Depressive Disorder, Depression, Mood Disorders, Suicidal Ideation | 06/24 | 07/24 | | |
| Active, not recruiting | N/A | 25 | US | tDCS | Washington University School of Medicine | Depressive Disorder, Treatment-Resistant | 06/24 | 06/24 | | |
| Recruiting | N/A | 100 | US | Sham-stimulation, Active-stimulation | Abbott Medical Devices | Treatment Resistant Depression | 04/27 | 04/29 | | |
UNCOVER, NCT04753385: The RECOVER sUb-study, Which Leverages quaNtitative and Credible Research tOols From Verily, Will providE Assessment measuRes for Depressive Episodes |
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| Terminated | N/A | 138 | US | | LivaNova | Treatment Resistant Depression | 09/24 | 09/24 | | |
RECOVER, NCT03887715: A Prospective, Multi-center, Randomized Controlled Blinded Trial Demonstrating the Safety and Effectiveness of VNS Therapy® System as Adjunctive Therapy Versus a No Stimulation Control in Subjects With Treatment-Resistant Depression |
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| Recruiting | N/A | 6800 | US | Vagus Nerve Stimulation (VNS), VNS | LivaNova | Treatment Resistant Depression | 02/28 | 12/30 | | |
Lucey, Brendan |
NCT05728736: Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau |
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| Withdrawn | 2 | 30 | US | Lemborexant 25 mg, Dayvigo, Placebo, inactive pill, sugar pil | Brendan Lucey, Eisai Inc. | Alzheimer Disease | 09/23 | 10/23 | | |
| Recruiting | 2 | 201 | US | Lemborexant 10 mg, DAYVIGO, Lemborexant 20mg, Placebo | Washington University School of Medicine, National Institutes of Health (NIH), Eisai Inc., National Institute on Aging (NIA) | Alzheimer Disease | 03/29 | 03/29 | | |
| Recruiting | 2 | 200 | US | Suvorexant 20 mg, Belsomra, Placebo, inactive pill, sugar pill | Washington University School of Medicine, Good Ventures, Merck Sharp & Dohme LLC | Sleep, Alzheimer Disease | 05/26 | 05/26 | | |
Neuman, Brian J |
NCT06368245: Durability of Suppl. Rod Constructs-SuppleMentAry Rod Technique for Long-segment Posterior Instrumented Spinal Fusions |
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| Not yet recruiting | N/A | 1244 | Europe, Canada, Japan, US, RoW | long-segment posterior TL instrumented fusion | AO Foundation, AO Spine | Spinal Fusion | 12/27 | 07/29 | | |
Toedebusch, Cristina |
NCT05728736: Acute Effect of Lemborexant on CSF Amyloid-Beta and Tau |
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| Withdrawn | 2 | 30 | US | Lemborexant 25 mg, Dayvigo, Placebo, inactive pill, sugar pil | Brendan Lucey, Eisai Inc. | Alzheimer Disease | 09/23 | 10/23 | | |
| Recruiting | 2 | 201 | US | Lemborexant 10 mg, DAYVIGO, Lemborexant 20mg, Placebo | Washington University School of Medicine, National Institutes of Health (NIH), Eisai Inc., National Institute on Aging (NIA) | Alzheimer Disease | 03/29 | 03/29 | | |
| Recruiting | 2 | 200 | US | Suvorexant 20 mg, Belsomra, Placebo, inactive pill, sugar pill | Washington University School of Medicine, Good Ventures, Merck Sharp & Dohme LLC | Sleep, Alzheimer Disease | 05/26 | 05/26 | | |