| DURIF, Franck |
| Active, not recruiting | 3 | 134 | Europe | Apomorphine, Apokinon, Best Medical Treatment | Rennes University Hospital | Parkinson's Disease | 12/23 | 01/25 | | |
PIMPARK, NCT03947216: Randomized Placebo Controlled Trial Evaluating the Efficacy of Pimavanserin, a Selective Serotonin 5-HydroxyTryptamine-2A (5HT2A) Inverse Agonist, to Treat Impulse Control Disorders in Parkinson's Disease. |
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| Completed | 2 | 117 | Europe | Active drug: pimavanserin 17mg (2 strength tablets), Placebo: 2 tablets containing same excipients except active compound, Assessment of severity of ICD (impulse control disorders), Assessment of motor and non-motors symptoms of PD Evaluation of hyper- and hypodopaminergic behaviors, Assessment of quality of life, Assessment of depression, Assessment of cognition, Assessment of severity of Parkinson Disease, Blood analysis, Cardiac monitoring | University Hospital, Strasbourg, France, NS-PARK, EUCLID Clinical Trial Platform, F-CRIN, ACADIA Pharmaceuticals Inc. | Parkinson Disease | 04/24 | 06/24 | | |
| Completed | N/A | 130 | Europe | FN scale auto-questionnaire | University Hospital, Grenoble, University Hospital, Clermont-Ferrand | Parkinson Disease, Fluctuating Mood Symptoms | 03/23 | 03/23 | | |
| Abergel, Armand |
NCT03695796: French Cohort for the Study of Non-invasive Tests of Liver Lesions in NAFLD/NASH (FreSH Cohort) |
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| Recruiting | N/A | 1000 | Europe | biopsy-proven NAFLD patients with non-invasive tests of liver fibrosis (blood tests, elastography devices) and biobank | University Hospital, Angers | NAFLD | 11/24 | 12/24 | | |
NCT03625726: Rôle of the Soluble Endothelial Protein C Receptor in Cirrhosis-associated Hypercoagulability State (EXERCISE) |
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| Recruiting | N/A | 300 | Europe | Thrombin generation assay (in vitro) | University Hospital, Clermont-Ferrand | Cirrhosis | 08/24 | 08/24 | | |
| Recruiting | N/A | 720 | Europe | Post-transplant addiction intervention | University Hospital, Montpellier | Alcohol Associated Liver Disease, Liver Transplantation | 09/26 | 09/28 | | |
| Recruiting | N/A | 800 | Europe | Blood draw for the laboratory assessment | ANRS, Emerging Infectious Diseases | Hepatitis D, Chronic, Hepatitis B, Chronic | 12/27 | 06/28 | | |
| CHABANNE, Russell |
NIPA, NCT05008926: The Study Naloxegol Administration to Prevent Opioids Induced Gastrointestinal Motility Disturbance in Brain Injured PAtients |
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| Recruiting | 3 | 370 | Europe | Naloxegol, Placebo | University Hospital, Brest | Brain Injuries | 10/25 | 04/26 | | |
HAP-DEX, NCT06269900: Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype |
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| Recruiting | 3 | 450 | Europe | Dexamethasone, Placebo | Nantes University Hospital | Hospital Acquired Pneumonia | 03/26 | 08/26 | | |
TREAT-HAP, NCT05914584: "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. |
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| Not yet recruiting | 3 | 450 | Europe | Baricitinib 4 MG | Nantes University Hospital | Hospital-acquired Pneumonia | 08/25 | 12/25 | | |
| Terminated | 2 | 92 | Europe, Japan, US, RoW | BIIB093, Glibenclamide, CIRARA, RP 1127, Placebo | Remedy Pharmaceuticals, Inc. | Brain Contusion | 06/23 | 06/23 | | |
| Recruiting | 2 | 50 | Europe | HYPERCAPNIA, NORMOCAPNIA | University Hospital, Clermont-Ferrand | Ischemic Stroke, Acute, Thrombectomy, Anesthesia, General, Cerebrovascular Circulation, Carbon Dioxide | 06/24 | 10/24 | | |
| Terminated | N/A | 37 | Europe | Deep sedation by Sevoflurane on the Morphotype of ARDS in ICU patieNts | University Hospital, Clermont-Ferrand | Acute Respiratory Distress Syndrome | 12/21 | 01/22 | | |
| Completed | N/A | 227 | Europe | Pleural drainage procedure with Seldinger procedure, Pleural drainage procedure with surgical-like technique | University Hospital, Clermont-Ferrand | Pleural Effusion, Pneumothorax, Hemothorax | 04/23 | 06/23 | | |
| Recruiting | N/A | 660 | Europe | Extubation readiness clinical score, Standard of care | University Hospital, Clermont-Ferrand, AZUREA Network (www.azurea.org), ANARLF Network, Direction Générale de l'Offre de Soin (DGOS) | Mechanical Ventilator Weaning, Acute Brain Injury, Altered Level of Consciousness, Mechanical Ventilation, Airway Control | 02/27 | 10/27 | | |
| CAMILLERI, Lionel |
| Terminated | N/A | 2758 | Europe, Canada, US, RoW | | Corcym S.r.l | Aortic Valve Disease, Aortic Stenosis | 03/21 | 03/21 | | |
| LECOMTE, Bénédicte Ms |
EPIREMED, NCT02757794: Long-term Effects of Visual Spatial Working Memory Training Program Performed at Preschool Age in Very Preterm Infants With Visual Spatial Working Memory Deficit. A Randomized Controlled Trial |
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| Completed | N/A | 166 | Europe | computerized cognitive remediation program, standard remediation | Assistance Publique Hopitaux De Marseille | Children Born Extremely Premature, Disturbance of Visuo-spatial Working Memory | 08/19 | 08/19 | | |
| PONS, Maguelonne |
LaparoDAN, NCT04174807: Prospective Study of Antenatal Diagnostic Criteria for Digestive Complications of Gastroschisis |
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| Recruiting | N/A | 200 | Europe, RoW | | University Hospital, Angers | Gastroschisis, Intestinal Occlusion | 05/22 | 05/22 | | |
CortECS, NCT04972734: Cohort of Premature Newborns for Charaterization of the Digestive Microbiota in Ulcerative Necrotizing Enterocolitis in Premature Infants |
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| Recruiting | N/A | 400 | Europe | premature newborns developing a NEC, premature newborns without NEC | University Hospital, Clermont-Ferrand, MEDIS Laboratory, QUAPA, ENTeRisk | Necrotizing Enterocolitis, Premature Birth | 01/25 | 01/25 | | |
PECUNIA, NCT06727877: Predictive Diagnosis of Ulcero-Necrotizing EnteroColitis in Premature Babies Using an Artificial Intelligence Approach Based on Early Analysis of the Fecal Microbiota |
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| Not yet recruiting | N/A | 1000 | Europe | Ability of early digestive microbiota analysis (using artificial intelligence) to predict the occurrence of NEC diagnosed according to the Bell classification. | University Hospital, Clermont-Ferrand | Necrotizing Enterocolitis (NEC), Healthy Control | 06/26 | 06/26 | | |
| Chauvet |
MISC-TRAIN, NCT06647849: Interest of Simulation Training on the Announcement of Early Pregnancy Loss on the Psychological Impact of the Patients |
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| Recruiting | N/A | 1000 | Europe | centers whose interns receive simulation training in the announcement of early spontaneous miscarriage between the 2 inclusion phases, centers with standard in-house management of spontaneous miscarriage/pregnancy arrested in the emergency department | University Hospital, Angers, Direction Générale de l'Offre de Soins | Early Pregnancy Loss, Spontaneous Miscarriage | 05/25 | 06/26 | | |
