| Granholm, Eric L |
NCT04486677: Caring Cards to and From Veterans: A Peer Approach to Suicide Prevention |
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| Completed | N/A | 80 | US | Caring Cards Group, Caring Cards Recipients | VA Office of Research and Development | Feasibility, Acceptability, Thwarted Belongingness, Perceived Burdensomeness, Suicide Risk, Social Connectedness | 09/22 | 11/22 | | |
mSITE, NCT05660070: Context-Aware Mobile Intervention for Social Recovery in Serious Mental Illness |
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| Completed | N/A | 46 | US | mobile Social Interaction Therapy by Exposure (mSITE) | University of California, San Diego | Schizophrenia, Schizoaffective Disorder, Mood Disorder, Psychotic | 09/24 | 09/24 | | |
| Recruiting | N/A | 50 | Canada, US | E-CBSST | University of California, San Diego, Centre for Addiction and Mental Health | Schizophrenia, Schizoaffective Disorder | 11/25 | 11/25 | | |
| Chang, Eric L |
NCT04305743: Post-procedural Pain Associated With 5 Versus 20 Intravesical Injections of Onabotulinumtoxin A |
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| Recruiting | 4 | 60 | US | OnabotulinumtoxinA 100 UNT, BOTOX | University of South Florida, Medstar Health Research Institute | Urinary Bladder, Overactive, Incontinence, Urge, Incontinence, Urinary, Urinary Urge Incontinence, Urinary Frequency More Than Once at Night, Nocturia | 01/21 | 06/21 | | |
| Recruiting | 4 | 61 | US | Surgical tumor resection, GammaTile radiation therapy implantation, Stupp protocol (EBRT and Temozolamide) | GT Medical Technologies, Inc. | Glioblastoma | 07/27 | 12/27 | | |
NCT04114981: Single Fraction Stereotactic Radiosurgery Compared with Fractionated Stereotactic Radiosurgery in Treating Patients with Resected Metastatic Brain Disease |
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| Active, not recruiting | 3 | 242 | Canada, US | Single Fraction Stereotactic Radiosurgery, Stereotactic Radiosurgery, Fractionated Stereotactic Radiosurgery, Quality-of-Life Assessment, Questionnaire Administration | Alliance for Clinical Trials in Oncology, National Cancer Institute (NCI) | Metastatic Malignant Neoplasm in the Brain | 03/26 | 03/28 | | |
NRG-BN003, NCT03180268: Observation or Radiation Therapy in Treating Patients With Newly Diagnosed Grade II Meningioma That Has Been Completely Removed by Surgery |
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| Recruiting | 3 | 148 | Canada, Japan, US, RoW | Clinical Observation, Radiation Therapy, Cancer Radiotherapy, Irradiate, Irradiated, Irradiation, RADIATION, Radiotherapeutics, Radiotherapy, RT, Therapy, Radiation | NRG Oncology, National Cancer Institute (NCI) | Grade II Meningioma, Intracranial Meningioma | 06/27 | 08/27 | | |
NCT04725838: Differential Target Multiplexed Spinal Cord Stimulation (DTM-SCS®) Real World Outcomes |
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| Completed | N/A | 255 | US | Medtronic Intellis™ and Vanta™ | Celéri Health, Inc., Medtronic | Chronic Pain | 07/23 | 07/23 | | |
| Morland, Leslie A |
| Active, not recruiting | 4 | 700 | US | Selective serotonin reuptake inhibitor, Serotonin-norepinephrine reuptake inhibitor, Written Exposure Therapy | University of Washington, Stanford University, Boston University, Washington State University, Patient-Centered Outcomes Research Institute | PTSD | 08/24 | 12/25 | | |
NCT04961190: A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD |
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| Recruiting | 4 | 300 | US | Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR, Pharmacotherapy with Paxil or Effexor XR | University of Pennsylvania, Patient-Centered Outcomes Research Institute, Corporal Michael J. Crescenz VA Medical Center, Coatesville VA Medical Center, Milwaukee VA Medical Center, North Texas Veterans Healthcare System, San Diego Veterans Healthcare System, VA Palo Alto Health Care System, Birmingham VA Health Care System | Posttraumatic Stress Disorder | 07/26 | 07/26 | | |
| Recruiting | 3 | 16 | US | 3,4-methylenedioxymethamphetamine (MDMA), Brief Cognitive Behavioral Conjoint Therapy (bCBCT) | Dr. Leslie Morland, Healing Breakthrough, Lykos Therapeutics, San Diego Veterans Healthcare System | PTSD, Relational Problems | 12/24 | 12/24 | | |
| Recruiting | 3 | 10 | US | 3,4 Methylenedioxymethamphetamine, MDMA, Prolonged Exposure, PE | Healing Breakthrough, San Diego Veterans Healthcare System, National Center for PTSD, White River Junction VA Medical Center, Lykos Therapeutics | Post-Traumatic Stress Disorder | 01/26 | 01/26 | | |
CBCT+OT, NCT05207436: Brief Cognitive Behavioral Conjoint Therapy for PTSD With Adjunctive Intranasal Oxytocin |
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| Completed | 2 | 20 | US | Oxytocin nasal spray, Pitocin, Brief Cognitive-Behavioral Conjoint Therapy, B-CBCT | San Diego Veterans Healthcare System | Post Traumatic Stress Disorder, Relational Problems | 09/22 | 12/22 | | |
| Recruiting | 2 | 240 | US | Oxytocin nasal spray, Pitocin, Saline nasal spray, Brief Cognitive-Behavioral Conjoint Therapy, bCBCT | VA Office of Research and Development | Post-Traumatic Stress Disorder (PTSD) | 04/28 | 04/28 | | |
| Recruiting | N/A | 144 | US | VA Standard Suicide Intervention, Treatment for Relationships and Safety Together (TR&ST) | VA Office of Research and Development | Suicide, Interpersonal Relations | 03/26 | 03/26 | | |
| Ross, Robert |
NAIAD, NCT01907295: National Cohort Study of Idiopathic and Heritable Pulmonary Arterial Hypertension |
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| Recruiting | N/A | 3600 | Europe | | University of Cambridge, British Heart Foundation, Medical Research Council | Pulmonary Arterial Hypertension | 12/22 | 12/22 | | |
| Recruiting | N/A | 200 | Canada | Low amount, low intensity exercise, Low amount, high intensity exercise, High amount, high intensity exercise | Queen's University | Exercise, Cardiorespiratory Fitness | 09/25 | 09/26 | | |
| Stein, Murray B |
| Completed | 2 | 63 | US | Cannabidiol, Epidiolex, Placebo | University of California, San Diego | Social Anxiety, Social Anxiety Disorder | 08/24 | 08/24 | | |
NCT02256644: Genomics of Posttraumatic Stress Disorder in Veterans |
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| Completed | N/A | 20000 | US | | VA Office of Research and Development | PTSD | 08/14 | 09/24 | | |
NCT04602806: Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Precision Medicine Phase 2 Option 1 |
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| Completed | N/A | 50 | US | | University of California, San Francisco, U.S. Army Medical Research and Development Command | Traumatic Brain Injury | 11/22 | 01/23 | | |
| Stepnowsky, Carl J |
| Completed | N/A | 270 | US | Sleep Apnea Self-Management Program, SASMP | VA Office of Research and Development | Obstructive Sleep Apnea | 03/23 | 04/23 | | |
| Recruiting | N/A | 240 | US | OMT Exercises, Nasal Breathing Exercises, Use of Nasal Lavage | VA Office of Research and Development | Obstructive Sleep Apnea | 03/25 | 06/25 | | |
| Daniels, Gregory A |
IGNYTE-3, NCT06264180: VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs |
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| Recruiting | 3 | 400 | US | Vusolimogene Oderparepvec, VO, RP1, Nivolumab, Opdivo, Nivolumab + Relatlimab, Opdualag, Pembrolizumab, Keytruda, Single-agent chemotherapy | Replimune Inc. | Advanced Melanoma | 01/29 | 08/34 | | |
| Recruiting | 2 | 25 | US | Binimetinib, Binimetinib Oral, Mektovi, ARRY-162, MEK162, Imatinib, Imatinib Mesylate | University of California, San Francisco, Array BioPharma | Melanoma Stage III, Melanoma Stage IV | 07/25 | 03/27 | | |
NCT03991130: High Dose IL-2 in Combination With Anti-PD-1 to Overcome Anti-PD-1 Resistance in Metastatic Melanoma and Renal Cell Carcinoma |
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| Recruiting | 2 | 25 | US | IL-2 and Nivolumab, High Dose IL-2, Anti-PD-1 | Gregory Daniels | Melanoma Stage Iv, Renal Cell Carcinoma, Metastatic | 08/24 | 08/26 | | |
| Recruiting | 2 | 340 | Europe, US | RP1, nivolumab, Opdivo | Replimune Inc., Bristol-Myers Squibb | Cancer, Melanoma (Skin), Mismatch Repair Deficiency, Microsatellite Instability, Non-melanoma Skin Cancer, Cutaneous Melanoma, NSCLC | 12/25 | 12/28 | | |
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NCT04157517: A Study of Modakafusp Alfa (TAK-573) Given by Itself and Together With Pembrolizumab in Adults With Advanced or Metastatic Solid Tumors |
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| Terminated | 1/2 | 45 | US, RoW | Modakafusp Alfa, TAK-573, Pembrolizumab | Takeda | Neoplasms, Melanoma | 12/23 | 12/23 | | |
| Active, not recruiting | 1/2 | 189 | US | XTX202 | Xilio Development, Inc., Xilio Development, Inc | Advanced Solid Tumor | 02/26 | 02/26 | | |
| Completed | 1/2 | 29 | Europe, US | ANV419, Pembrolizumab, Ipilimumab | Anaveon AG, Anaveon AG | Melanoma (Skin), Cutaneous Melanoma, Adult Disease, Advanced Solid Tumor, Metastatic Melanoma | 08/24 | 08/24 | | |
NCT05580770: Mirdametinib + BGB-3245 in Advanced Solid Tumors |
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| Active, not recruiting | 1/2 | 23 | US, RoW | Mirdametinib, PD-0325901, BGB-3245 | SpringWorks Therapeutics, Inc. | Advanced Solid Tumor | 10/26 | 06/27 | | |
ARTACUS, NCT04349436: A Phase 1B/2 Study of RP1 in Solid Organ Transplant Patients With Advanced Cutaneous Malignancies |
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| Recruiting | 1/2 | 65 | US | RP1, intra-tumoral injection, oncolytic virus | Replimune Inc. | Cutaneous Squamous Cell Carcinoma, Merkel Cell Carcinoma, Basal Cell Carcinoma, Melanoma | 09/27 | 01/28 | | |
NCT03991741: Adoptive Cell Transfer of Autologous Tumor Infiltrating Lymphocytes and High-Dose Interleukin 2 in Select Solid Tumors |
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| Recruiting | 1 | 24 | US | Autologous Tumor Infiltrating Lymphocytes, High-Dose Interleukin 2 | Gregory Daniels, Immunotherapy Foundation | Metastatic Melanoma, Locally Advanced Refractory/Recurrent Melanoma, Metastatic Head and Neck Cancer, Locally Advanced Refractory/Recurrent Head and Neck Cancer | 08/24 | 08/26 | | |
MAST, NCT05346484: A Study of CF33-hNIS (VAXINIA), an Oncolytic Virus, as Monotherapy or in Combination With Pembrolizumab in Adults With Metastatic or Advanced Solid Tumors |
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| Recruiting | 1 | 100 | US, RoW | CF33-hNIS, VAXINIA, HOV2, Pembrolizumab, KEYTRUDA® | Imugene Limited | Solid Tumor, Solid Carcinoma, Solid Tumor, Adult, Metastatic Cancer, Advanced Solid Tumor, Cholangiocarcinoma, Bile Duct Cancer | 12/24 | 01/25 | | |
| Leung, Albert |
NCT05351801: Proof of Concept Trial of Cannabis Derivatives in Neuropathic Pain |
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| Recruiting | 2 | 320 | US | THC (Syndros), CBD (Epidolex), THC + CBD (Nabiximols), Placebo | VA Office of Research and Development | Diabetic Neuropathic Pain, Peripheral Neuropathic Pain | 06/27 | 06/27 | | |
NCT03314584: Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic Stimulation |
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| Completed | N/A | 179 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation, Magnetic resonance imaging (MRI) | VA Office of Research and Development | Traumatic Brain Injury (TBI) | 09/23 | 01/24 | | |
NCT04182659: Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms |
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| Recruiting | N/A | 150 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation | Veterans Medical Research Foundation, United States Department of Defense | Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain, Joint Pain | 09/23 | 09/23 | | |
NCT05176392: Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches |
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| Recruiting | N/A | 240 | US | Active rTMS, Headache Management Therapy, Sham rTMS, Headache Education Control | Veterans Medical Research Foundation | TBI (Traumatic Brain Injury), Headache, Depression | 08/25 | 08/25 | | |
NCT04046536: rTMS in Alleviating Pain and Co-Morbid Symptoms in Gulf War Veterans Illness (GWVI) |
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| Recruiting | N/A | 80 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation | VA Office of Research and Development | Gulf War Illness, Depression | 09/25 | 09/25 | | |
| Wachsman, William |
NCT02799485: sEphB4-HSA in Treating Patients With Kaposi Sarcoma |
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| Active, not recruiting | 2 | 23 | US | Laboratory Biomarker Analysis, Pharmacological Study, Quality-of-Life Assessment, Quality of Life Assessment, Recombinant EphB4-HSA Fusion Protein, sEphB4-HSA | AIDS Malignancy Consortium, National Cancer Institute (NCI), Vasgene Therapeutics, Inc, The Emmes Company, LLC, University of Arkansas | Skin Kaposi Sarcoma | 12/25 | 06/26 | | |
| Norman, Sonya |
| Completed | 2/3 | 100 | US | topiramate, prolonged exposure, placebo | VA Office of Research and Development, University of California, San Diego | PTSD and Alcohol Use Disorder | 10/22 | 09/23 | | |
| Recruiting | N/A | 188 | US | Trauma Informed Guilt Reduction Therapy, Supportive Care Therapy | Veterans Medical Research Foundation, United States Department of Defense, Brown University, Seattle Institute for Biomedical and Clinical Research, White River Junction Veterans Affairs Medical Center, San Diego Veterans Healthcare System, Providence VA Medical Center, National Center for PTSD | Guilt, Shame, Post-traumatic Stress Disorders | 10/22 | 10/23 | | |
| Completed | N/A | 426 | US | Prolonged Exposure Therapy, Cognitive Processing Therapy, Present Centered Therapy | Center for Veterans Research and Education, Patient-Centered Outcomes Research Institute, Minneapolis Veterans Affairs Medical Center | Stress Disorders, Post-Traumatic, Substance Use Disorders | 04/24 | 04/24 | | |
| Not yet recruiting | N/A | 200 | US | Prolonged Exposure Therapy | Veterans Medical Research Foundation, University of Minnesota, Center for Veterans Research and Education | Stress Disorders, Post-Traumatic, Substance Use Disorders | 07/27 | 08/27 | | |
| Recruiting | N/A | 158 | US | Trauma Informed Guilt Reduction Therapy, TrIGR, Cognitive Processing Therapy, CPT | VA Office of Research and Development | PTSD | 03/27 | 09/27 | | |
| Twamley, Elizabeth W |
PACT, NCT04560946: Personalized, Augmented Cognitive Training () for Service Members and Veterans with a History of TBI |
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| Completed | N/A | 107 | US | Personalized Augmented Cognitive Training (PACT), Enhanced Treatment As Usual | Veterans Medical Research Foundation, United States Naval Medical Center, San Diego | Traumatic Brain Injury | 09/23 | 09/23 | | |
NCT03225482: Cognitive Rehabilitation Therapy for Mild Cognitive Impairment |
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| Completed | N/A | 193 | US | Motivationally Enhanced Compensatory Cognitive Training, ME-CCT, Goal-focused Supportive Contact, SC | VA Office of Research and Development, Portland VA Medical Center | Mild Cognitive Impairment | 06/24 | 06/24 | | |
NCT05985356: Neuromodulation for Comorbid Hoarding Disorder and Depression |
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| Recruiting | N/A | 12 | US | iTBS, rTMS | University of California, San Diego | Hoarding Disorder, Hoarding, Depression | 01/25 | 01/25 | | |
NCT05682677: Combined Neuromodulation and Cognitive Training for Post-mTBI Depression |
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| Recruiting | N/A | 72 | US | iTBS, sham iTBS, Personalized, Augmented Cognitive Training (PACT) | University of California, San Diego, San Diego Veterans Healthcare System | Depression, Mild Traumatic Brain Injury, Concussion, Brain | 06/26 | 06/26 | | |
| Shah, Nilesh |
| Recruiting | 4 | 7410 | US | Metformin XR, Placebo | VA Office of Research and Development | Prediabetic State, Atherosclerosis, Metformin | 03/29 | 03/29 | | |
| Recruiting | 3 | 170 | Europe | XyloCore Low Strenght, XyloCore Medium Strenght, XyloCore High Strenght, XyloCore 0.7 or 1.5 or 2.0, 1.36%, 1.5%, 2.27%, 2.5%, 3.86%, 2.25% Glucose PD Solution, Physioneal 40 or 35, Fixioneal 40 or 35, Dianeal, Balance, Bicavera, Bicanova, Equibalance | Iperboreal Pharma Srl, Iperboreal Pharma Srl, | End Stage Renal Disease | 12/24 | 12/24 | | |
| Afari, Niloofar |
NCT03029507: An ACT-enhanced Weight Management and Fitness Program for Navy Personnel |
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| Active, not recruiting | N/A | 178 | US | ACT Enhanced ShipShape, Standard ShipShape (SS) | Veterans Medical Research Foundation, San Diego Veterans Healthcare System, United States Naval Medical Center, San Diego | Obesity, Overweight | 07/22 | 07/22 | | |
| Completed | N/A | 126 | US | Mindful Action for Pain, MAP, Cognitive Behavioral Therapy for Chronic Pain, CBT-CP | VA Office of Research and Development | Chronic Pain | 09/23 | 03/24 | | |
| Grubbs, Kathleen M |
NCT04961190: A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD |
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| Recruiting | 4 | 300 | US | Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR, Pharmacotherapy with Paxil or Effexor XR | University of Pennsylvania, Patient-Centered Outcomes Research Institute, Corporal Michael J. Crescenz VA Medical Center, Coatesville VA Medical Center, Milwaukee VA Medical Center, North Texas Veterans Healthcare System, San Diego Veterans Healthcare System, VA Palo Alto Health Care System, Birmingham VA Health Care System | Posttraumatic Stress Disorder | 07/26 | 07/26 | | |
| Sarmiento, Kathleen F |
| Recruiting | N/A | 2413 | US | | VA Office of Research and Development, San Francisco Veterans Affairs Medical Center | Obstructive Sleep Apnea (OSA) | 09/25 | 09/25 | | |
| McCarthy, Michael J |
| Recruiting | 3 | 220 | Europe, Canada, US, RoW | Selinexor, KPT-330, Matching Placebo for selinexor | Karyopharm Therapeutics Inc, GOG Foundation, European Network of Gynaecological Oncological Trial Groups (ENGOT), Belgium and Luxembourg Gynaecological Oncology Group, North Eastern German Society of Gynaecological Oncology, Multicentre Italian Trials in Ovarian Cancer and Gynecologic Malignancies, Spanish Research Group in Ovarian Cancer, The Central and Eastern European Gynecologic Oncology Group, Israeli Society of Gynecologic Oncology, Australia New Zealand Gynaecological Oncology Group | Endometrial Cancer | 01/25 | 01/28 | | |
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| Sakamoto, Kyoko |
NCT04943380: Efficacy and Utility of Cxbladder Tests in Hematuria Patients |
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| Active, not recruiting | N/A | 684 | US | Cxbladder | Pacific Edge Limited | Hematuria, Urothelial Carcinoma | 01/24 | 12/25 | | |
| Mudaliar, Sunder R |
| Active, not recruiting | 3 | 2779 | US | DPPOS Group Lifestyle, Metformin, Glucophage, DPPOS Boost Lifestyle, Intensive Lifestyle Group Session, Intensive lifestyle session (ILS) | National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD), National Institute on Aging (NIA), National Institute on Minority Health and Health Disparities (NIMHD), National Heart, Lung, and Blood Institute (NHLBI), National Cancer Institute (NCI), National Eye Institute (NEI), National Center for Research Resources (NCRR), Office of Research on Women's Health (ORWH), Centers for Disease Control and Prevention, American Diabetes Association, Indian Health Service, General Clinical Research Program, US Department of Veterans Affairs | Diabetes Mellitus, Cancer, CVD | 10/24 | 01/25 | | |
| Pettus, Jeremy |
| Active, not recruiting | 2 | 140 | Europe, US, RoW | Ladarixin, allosteric inhibitor of CXCL8 (IL-8), CXCR1 and CXCR2 receptors, Placebo | Dompé Farmaceutici S.p.A, Dompe farmaceutici s.p.a. | Recent Onset type1 Diabetes | 04/24 | 04/26 | | |
COBRA, NCT05281614: Immune Effects of Vedolizumab With or Without Anti-TNF Pre-treatment in T1D |
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| Completed | 1 | 20 | US | Etanercept, Enbrel, Vedolizumab, Entyvio | Benaroya Research Institute, University of California, San Diego | Type 1 Diabetes | 01/24 | 01/24 | | |
| Not yet recruiting | 1 | 30 | US | THC, Cannabis, Placebo | University of California, San Diego, Center for Medicinal Cannabis Research | Type 2 Diabetes | 02/27 | 06/27 | | |
NCT03310359: Clinical Trial of Anti-oxidant Astaxanthin in Insulin-resistant Subjects |
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| Completed | N/A | 34 | US | Astaxanthin, Haematococcus pluvialis, Placebo | University of California, San Diego | Metabolic Syndrome X | 03/21 | 12/22 | | |
AID4MDI, NCT06627517: Safety and Effectiveness of the Luna System in People with Type 1 Diabetes Mellitus |
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| Recruiting | N/A | 130 | US | Episodic overnight patch pump | Luna Diabetes | Type 1 Diabetes Mellitus, Sleep Quality | 05/25 | 08/25 | | |
| Not yet recruiting | N/A | 324 | Europe, US, RoW | Omnipod 5 or Medtronic 780G, My HypoCOMPaSS Education, HARPdoc Education | Milton S. Hershey Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Minnesota, University of Kentucky, University of Pennsylvania, AdventHealth, University of Leicester, University of Sheffield, University of Melbourne, Jaeb Center for Health Research, University of California, San Diego | Diabetes Mellitus, Type 1 | 06/27 | 12/27 | | |
| Rutledge, Thomas |
| Not yet recruiting | 3 | 450 | NA | TM, PCT | David Lynch Foundation | Ptsd, Depressive Symptoms, Suicidal Ideation, Alcohol Use, Unspecified | 12/23 | 12/23 | | |
NCT05634291: Effects of the Nottingham Augmented Reality (AR) App for Arthritis Hand Joint Pain |
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| Completed | N/A | 36 | US | Standard of care, Nottingham AR smartphone app with active intervention | VRx Medical Inc, National Institute on Drug Abuse (NIDA), San Diego Veterans Healthcare System | Chronic Pain, Arthritis Hand, Opioid Use | 06/23 | 07/23 | | |
| Colvonen, Peter |
NCT05242367: Electrical Vestibular Nerve Stimulation (VeNS) As a Treatment for PTSD |
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| Completed | N/A | 381 | US | Modius Spero active device, Sham device | Neurovalens Ltd., University of California, San Diego, Clinical Trial Mentors | Post Traumatic Stress Disorder | 12/24 | 12/24 | | |
NCT06470035: Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD) |
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| Not yet recruiting | N/A | 170 | Europe, US | Active VeNS Device, Modius Mood, Sham VeNS Device | Neurovalens Ltd. | Major Depressive Disorder \(MDD, Depressive Disorder, Major | 04/27 | 04/27 | | |
NCT05156112: OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit |
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| Recruiting | N/A | 194 | US | Positive Airway Pressure Device, PAP; CPAP; Auto-PAP | VA Office of Research and Development | Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program | 05/27 | 05/27 | | |
| Han, Frederick |
LESS-VT, NCT03490201: FLExAbility Sensor Enabled Substrate Targeted Ablation for the Reduction of VT Study |
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| Completed | N/A | 592 | Europe, US, RoW | Market Approved RF Ablation System, FlexAbility SE Ablation Catheter | Abbott Medical Devices | Ventricular Tachycardia | 04/24 | 04/24 | | |
| Active, not recruiting | N/A | 200 | Europe, Canada, US | Adagio AF Cryoablation System (iCLAS™) | Adagio Medical | Persistent Atrial Fibrillation | 08/23 | 08/24 | | |
| Modir, Royya |
| Recruiting | 2 | 300 | US | TS23 | Translational Sciences, Inc., University of Cincinnati, National Institute of Neurological Disorders and Stroke (NINDS), Medical University of South Carolina, University of Arizona | Ischemic Stroke | 07/27 | 12/27 | | |
| Rifkin, Dena Evette |
| Recruiting | 2 | 200 | US | Pirfenidone, ESBRIET, matching placebo | Veterans Medical Research Foundation, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), San Diego Veterans Healthcare System, University of California, San Diego, University of California, San Francisco, Genentech, Inc. | Chronic Kidney Disease | 05/24 | 12/24 | | |
NCT03224624: Self-management of Blood Pressure Medication for Hypertensive Veterans |
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| Completed | N/A | 232 | US | self-management protocol for hypertension care | VA Office of Research and Development | Hypertension | 03/23 | 03/23 | | |
| Schulteis, Gerhard H |
NCT05634291: Effects of the Nottingham Augmented Reality (AR) App for Arthritis Hand Joint Pain |
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| Completed | N/A | 36 | US | Standard of care, Nottingham AR smartphone app with active intervention | VRx Medical Inc, National Institute on Drug Abuse (NIDA), San Diego Veterans Healthcare System | Chronic Pain, Arthritis Hand, Opioid Use | 06/23 | 07/23 | | |
NCT04506164: Effectiveness and Implementation of eScreening in Post 9/11 Transition Programs |
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| Active, not recruiting | N/A | 69 | US | Multicomponent Implementation Strategy, eScreening | VA Office of Research and Development | Depression, Stress Disorders, Post-Traumatic, Suicide | 12/23 | 12/24 | | |
| Completed | N/A | 25 | US | Sleep-SMART | VA Office of Research and Development | Insomnia, Mild Cognitive Impairment | 12/23 | 12/23 | | |
SOA, NCT05994482: Surveillance Colonoscopy in Older Adults: The SurvOlderAdults Study |
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| Recruiting | N/A | 130000 | US | adenoma vs no adenoma, colonoscopy vs no colonoscopy, survey and expert panel | VA Office of Research and Development | Colorectal Cancer | 10/25 | 09/27 | | |
NCT05724498: Brief Versus Standard Cognitive Behavioral Therapy for Insomnia in Veterans |
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| Recruiting | N/A | 250 | US | Brief CBT-I, Standard CBT-I | VA Office of Research and Development, VA Finger Lakes Healthcare System | Insomnia | 07/26 | 10/26 | | |
| Recruiting | N/A | 158 | US | Trauma Informed Guilt Reduction Therapy, TrIGR, Cognitive Processing Therapy, CPT | VA Office of Research and Development | PTSD | 03/27 | 09/27 | | |
NCT05156112: OSA PAP Treatment for Veterans With SUD and PTSD on Residential Treatment Unit |
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| Recruiting | N/A | 194 | US | Positive Airway Pressure Device, PAP; CPAP; Auto-PAP | VA Office of Research and Development | Post Traumatic Stress Disorder, Obstructive Sleep Apnea, Substance Use Disorder, Residential Treatment Program | 05/27 | 05/27 | | |
AID-CCT, NCT05770479: Assessing and Improving the Durability of Compensatory Cognitive Training for Older Veterans |
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| Enrolling by invitation | N/A | 28 | US | Motivationally-Enhanced Compensatory Cognitive Training (ME-CCT) Booster Modules, ME-CCT Booster, Treatment As Usual, TAU | VA Office of Research and Development | Mild Cognitive Impairment | 06/28 | 06/28 | | |
WB, NCT05963607: RCT of a Weighted Blanket to Reduce Pain in Veterans With Chronic Pain |
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| Recruiting | N/A | 160 | US | Weighted blanket | VA Office of Research and Development | Chronic Pain, Sleep Disturbance | 04/29 | 09/29 | | |
| Krummen, David E |
NCT02169037: Substrate Versus Trigger Ablation for Paroxysmal Atrial Fibrillation |
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| Recruiting | N/A | 120 | US | FIRM Ablation, Conventional AF ablation with PVI | University of California, San Diego, National Institutes of Health (NIH), National Heart, Lung, and Blood Institute (NHLBI) | Atrial Fibrillation | 07/22 | 07/22 | | |
RECONFIRM, NCT02456233: Evaluation of Conventional Ablation With or Without Focal Impulse and Rotor Modulation to Eliminate Human AF |
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| Recruiting | N/A | 120 | US | Conventional AF Ablation with PVI, FIRM-guided ablation plus PVI | Stanford University | Atrial Fibrillation | 03/25 | 12/25 | | |
| Ix, Joachim H |
| Recruiting | 2 | 200 | US | Pirfenidone, ESBRIET, matching placebo | Veterans Medical Research Foundation, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), San Diego Veterans Healthcare System, University of California, San Diego, University of California, San Francisco, Genentech, Inc. | Chronic Kidney Disease | 05/24 | 12/24 | | |
| Active, not recruiting | N/A | 28 | US | AMIA with SHARESOURCE Connectivity Platform, Baxter AMIA, SHARESOURCE, HomeChoice PRO, Baxter HomeChoice PRO | University of California, San Diego, Baxter Healthcare Corporation, Scripps Health, Home Dialysis Therapies of San Diego | Efficacy, Safety Issues | 11/21 | 04/22 | | |
| Kunnel, Alphonsa |
NCT03314584: Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic Stimulation |
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| Completed | N/A | 179 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation, Magnetic resonance imaging (MRI) | VA Office of Research and Development | Traumatic Brain Injury (TBI) | 09/23 | 01/24 | | |
| Gardetto, Nancy J |
DETECT-HF, NCT06378632: AN INTERNATIONAL, OBSERVATIONAL, BLINDED STUDY TO ASSESS THE PERFORMANCE OF THE CORDIO HEARO SYSTEM |
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| Recruiting | N/A | 500 | Europe, US, RoW | Hearo App | Cordio Medical | Heart Failure | 01/25 | 03/25 | | |
| Castro, Erick O |
| Recruiting | 2 | 200 | US | Pirfenidone, ESBRIET, matching placebo | Veterans Medical Research Foundation, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), San Diego Veterans Healthcare System, University of California, San Diego, University of California, San Francisco, Genentech, Inc. | Chronic Kidney Disease | 05/24 | 12/24 | | |
| Ho, Gordon |
| Not yet recruiting | N/A | 36 | US | Functional Substrate-Only Mapping without VT Induction, Isochronal late activation mapping (ILAM), peak frequency analysis, Standard-of-Care Mapping/Imaging | VA Office of Research and Development | Ventricular Tachycardia, Sudden Cardiac Death | 03/28 | 09/28 | | |
| Collin, Lauren M |
NCT03314584: Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic Stimulation |
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| Completed | N/A | 179 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation, Magnetic resonance imaging (MRI) | VA Office of Research and Development | Traumatic Brain Injury (TBI) | 09/23 | 01/24 | | |
NCT04182659: Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms |
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| Recruiting | N/A | 150 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation | Veterans Medical Research Foundation, United States Department of Defense | Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain, Joint Pain | 09/23 | 09/23 | | |
NCT05176392: Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches |
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| Recruiting | N/A | 240 | US | Active rTMS, Headache Management Therapy, Sham rTMS, Headache Education Control | Veterans Medical Research Foundation | TBI (Traumatic Brain Injury), Headache, Depression | 08/25 | 08/25 | | |
NCT04046536: rTMS in Alleviating Pain and Co-Morbid Symptoms in Gulf War Veterans Illness (GWVI) |
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| Recruiting | N/A | 80 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation | VA Office of Research and Development | Gulf War Illness, Depression | 09/25 | 09/25 | | |
| Lopez, Caleb |
NCT03314584: Managing Mild Traumatic Brain Injury Related Headaches With Repetitive Transcranial Magnetic Stimulation |
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| Completed | N/A | 179 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation, Magnetic resonance imaging (MRI) | VA Office of Research and Development | Traumatic Brain Injury (TBI) | 09/23 | 01/24 | | |
NCT04182659: Long Term Efficacy of Neuronavigation Guided rTMS in Alleviating Gulf War Illness Related Headaches and Pain Symptoms |
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| Recruiting | N/A | 150 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation | Veterans Medical Research Foundation, United States Department of Defense | Gulf War Syndrome, Gulf War Illness, Headache, Muscle Pain, Joint Pain | 09/23 | 09/23 | | |
NCT05176392: Combined Transcranial Magnetic Stimulation and Therapy for MTBI Related Headaches |
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| Recruiting | N/A | 240 | US | Active rTMS, Headache Management Therapy, Sham rTMS, Headache Education Control | Veterans Medical Research Foundation | TBI (Traumatic Brain Injury), Headache, Depression | 08/25 | 08/25 | | |
NCT04046536: rTMS in Alleviating Pain and Co-Morbid Symptoms in Gulf War Veterans Illness (GWVI) |
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| Recruiting | N/A | 80 | US | Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation | VA Office of Research and Development | Gulf War Illness, Depression | 09/25 | 09/25 | | |
| Puhalla, Alexander |
NCT04961190: A Comparison of Prolonged Exposure Therapy, Pharmacotherapy, and Their Combination for PTSD |
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| Recruiting | 4 | 300 | US | Prolonged Exposure Therapy, Pharmacotherapy with paroxetine or venlafaxine XR, Pharmacotherapy with Paxil or Effexor XR | University of Pennsylvania, Patient-Centered Outcomes Research Institute, Corporal Michael J. Crescenz VA Medical Center, Coatesville VA Medical Center, Milwaukee VA Medical Center, North Texas Veterans Healthcare System, San Diego Veterans Healthcare System, VA Palo Alto Health Care System, Birmingham VA Health Care System | Posttraumatic Stress Disorder | 07/26 | 07/26 | | |
| Looney, David |
| Recruiting | 3 | 852 | Europe, Canada, US, RoW | VE303, Placebo | Vedanta Biosciences, Inc. | Clostridium Difficile, Clostridium Difficile Infections, Clostridium Difficile Infection Recurrence, Clostridioides Difficile Infection, Clostridioides Difficile Infection Recurrence, CDI, C. Diff Infection, Recurrent Clostridium Difficile Infection, C.Difficile Diarrhea, Diarrhea Infectious | 06/27 | 10/27 | | |
