| Eriksson, Jan |
| Active, not recruiting | 4 | 2067 | Europe | Metformin, Dapagliflozin 10 MG | Uppsala University, Uppsala University Hospital, Swedish Healthcare Regions, Swedish National Board of Health and Welfare, The Swedish National Diabetes Register | Type 2 Diabetes | 10/25 | 10/25 | | |
| Terminated | 2 | 1 | Europe | ILP100-Topical (emilimogene sigulactibac) 5x10^7 CFU/cm^2, ILP100-Topical, ILP100-Topical (emilimogene sigulactibac) 1x10^9 CFU/cm^2, Placebo | Ilya Pharma, European Commission | Wound Heal, Wound Healing Disturbance of, Wound Healing Disorder, Wound Healing Delayed, Diabetic Foot Ulcer, Diabetic Foot Ulcer Mixed | 12/24 | 12/24 | | |
| Johansson, Elias P |
| Recruiting | 3 | 1260 | Europe | Imatinib 400mg, Placebo Oral Tablet | Niaz Ahmed | Acute Ischaemic Stroke | 12/22 | 06/23 | | |
| Andersen, Peter |
| Recruiting | 3 | 150 | Europe, Canada, Japan, US, RoW | Tofersen, BIIB067, QALSODY, Placebo | Biogen | Amyotrophic Lateral Sclerosis Associated With a SOD1 Gene Mutation | 08/27 | 08/27 | | |
NCT05039099 / 2020-005971-11: A Study to Evaluate, Safety, Tolerability, Pharmacodynamic (PD) Markers and Pharmacokinetics (PK) of AP-101 in Participants With Amyotrophic Lateral Sclerosis (ALS) |
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| Active, not recruiting | 2 | 63 | Europe, Canada, US, RoW | AP-101, Placebo | AL-S Pharma, AL-S Pharma | Amyotrophic Lateral Sclerosis | 12/24 | 10/25 | | |
TENPLA, NCT04891549: Tension Band Versus Locking Plate Fixation for the Treatment of Patella Fractures |
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| Recruiting | N/A | 122 | Europe | Tension band fixation, Plate fixation | Rasmus Elsøe, Aarhus University Hospital, Randers Regional Hospital, Regional Hospital Hjoerring, Regional Hospital Kolding, Viborg Regional Hospital | Patella Fracture, Surgery, Orthopedic Disorder | 09/24 | 09/26 | | |
| Haapamäki, Markku M |
NEAPE, NCT01347697: Collagen Implant (Biological Mesh) Versus GM Flap for Reconstruction of Pelvic Floor After ELAPE in Rectal Cancer |
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| Active, not recruiting | N/A | 91 | Europe | Reconstruction with an acellular porcine dermal collagen implant (biological mesh), Reconstruction with a gluteus maximus myocutaneous flap | Umeå University, The Swedish Society of Medicine, Västerbotten County Council, Sweden | Rectal Cancer, Defect of Floor of Lesser Pelvis | 09/23 | 09/24 | | |
| Strigård, Karin |
| Recruiting | N/A | 100 | Europe | Endostomal three-dimensional ultrasonography, Computerized tomography of the abdomen, Clinical examination, Evaluation at laparotomy/laparoscopy | Umeå University | Parastomal Hernia | 12/21 | 12/21 | | |
| Completed | N/A | 85 | Europe | Physical activity | Umeå University, Västerbotten County Council, Sweden | Colon Cancer, Physical Activity | 02/24 | 02/24 | | |
SFINX, NCT06763861: Sacral Neuromodulation and Faecal Incontinence and Its Unknown Effect on the External Anal Sphincter |
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| Recruiting | N/A | 15 | Europe | Biopsy | Umeå University | Fecal Incontinence | 12/26 | 12/28 | | |
NCT02306382: Multicenter Study for Diagnosis and Treatment of Perianal Abscesses |
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| Recruiting | N/A | 200 | Europe | Perianal abscess drainage, 1, 3D ultrasonography, 2 | University Hospital, Umeå | Perianal Abscess, Anal Fistulas, Incontinence | 12/25 | 12/28 | | |
| Recruiting | N/A | 90 | Europe | Repair of parastomal hernia | Umeå University | Parastomal Hernia | 12/25 | 12/25 | | |
| Boniface, Jana M de |
SENOMAC, NCT02240472: Sentinel Node Biopsy in Breast Cancer: Omission of Axillary Clearance After Macrometastases. A Randomized Trial. |
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| Active, not recruiting | N/A | 2700 | Europe | Omission of axillary clearance | Karolinska Institutet, The Swedish Research Council, Swedish Cancer Foundation, Nordic Cancer Union | Breast Cancer | 12/21 | 12/26 | | |
SENOMIC, NCT02049632: Sentinel Node Biopsy in Breast Cancner: Omission of Axillary Clearance After Micrometastasis |
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| Completed | N/A | 805 | Europe | Omission of axillary clearance | Karolinska Institutet, Centrallasarettet Västerås, Uppsala University | Breast Cancer | 12/22 | 12/22 | | |
| Recruiting | N/A | 712 | Europe, RoW | Physical training | Karolinska Institutet | Breast Cancer | 12/25 | 12/27 | | |
OPBC-02PREPEC, NCT04293146: Pre- Versus Sub-pectoral Implant-based Breast Reconstruction After Skin-sparing Mastectomy or Nipple-sparing Mastectomy |
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| Active, not recruiting | N/A | 382 | Europe, US | pre-pectoral IBBR, sub-pectoral IBBR | University Hospital, Basel, Switzerland, Swiss National Science Foundation | Breast Reconstruction, Implant-Based Breast Reconstruction (IBBR) | 05/25 | 02/33 | | |
| Mukka, Sebastian S |
DAICY, NCT05164081: Dual vs. Single-Antibiotic Impregnated Cement in Hemiarthroplasty for Femoral Neck Fracture |
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| Recruiting | 3 | 7000 | Europe | antibiotic loaded bone cement (gentamicin+clindamycin) COPAL G+C (Heraeus)., antibiotic loaded bone cement (gentamicin) Paladins R+G (Heraeus) or Refobacin (Biomet). | Umeå University, Region Västerbotten | Femoral Neck Fractures, Prosthetic Infection | 01/26 | 01/27 | | |
HipSTHeR, NCT03966716: Hips Screws or (Total) Hip Replacement for Undisplaced Femoral Neck Fractures in Elderly Patients |
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| Recruiting | N/A | 1440 | Europe | Arthroplasty, Internal Fixation | Uppsala University, The Swedish Research Council | Femoral Neck Fractures, Undisplaced Fracture | 12/25 | 09/26 | | |
| Active, not recruiting | N/A | 202 | Europe | Surgical stabilization | Uppsala University, Sahlgrenska University Hospital, Uppsala University Hospital, University Hospital, Umeå, University Hospital, Linkoeping, Skane University Hospital, Region Örebro County, Stockholm South General Hospital, Karolinska University Hospital, Oslo University Hospital, Haukeland University Hospital, Helse Stavanger HF, University Hospital, Akershus, Kalmar County Hospital, Ryhov County Hospital, Halmstad County Hospital, Centrallasarettet Västerås, St. Olavs Hospital | Thoracolumbar Burst Fracture | 02/26 | 12/36 | | |
| Active, not recruiting | N/A | 70 | Europe | MobilLINK TrabecuLINK cup, Pinnacle Gription cup | Umeå University, University Hospital, Umeå, Region Västerbotten | Osteoarthritis, Hip | 09/26 | 09/39 | | |
| Ryden, Lisa |
SENOMAC, NCT02240472: Sentinel Node Biopsy in Breast Cancer: Omission of Axillary Clearance After Macrometastases. A Randomized Trial. |
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| Active, not recruiting | N/A | 2700 | Europe | Omission of axillary clearance | Karolinska Institutet, The Swedish Research Council, Swedish Cancer Foundation, Nordic Cancer Union | Breast Cancer | 12/21 | 12/26 | | |
| Sund, Malin |
SENOMAC, NCT02240472: Sentinel Node Biopsy in Breast Cancer: Omission of Axillary Clearance After Macrometastases. A Randomized Trial. |
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| Active, not recruiting | N/A | 2700 | Europe | Omission of axillary clearance | Karolinska Institutet, The Swedish Research Council, Swedish Cancer Foundation, Nordic Cancer Union | Breast Cancer | 12/21 | 12/26 | | |
SENOMIC, NCT02049632: Sentinel Node Biopsy in Breast Cancner: Omission of Axillary Clearance After Micrometastasis |
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| Completed | N/A | 805 | Europe | Omission of axillary clearance | Karolinska Institutet, Centrallasarettet Västerås, Uppsala University | Breast Cancer | 12/22 | 12/22 | | |
| Zackrisson, Björn |
ARTSCAN VI, NCT06248996: a Multicentre Phase III Study of Risk-based Treatment Intensification With Hyperfractionated Radiotherapy in Head and Neck Cancer Patients |
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| Recruiting | 3 | 308 | Europe | Hyperfractionated radiotherpy, HFX-RT, Control group, standard treatment | Lund University Hospital | Head and Neck Squamous Cell Carcinoma | 03/28 | 03/33 | | |
| Completed | N/A | 118 | Europe | | Umeå University, Lund University | Squamous Carcinoma, Head and Neck Cancer, Anal Cancer, Lung Cancer, Esophageal Cancer, Cervix Cancer | 05/23 | 05/23 | | |
| Recruiting | N/A | 100 | Europe | Proton radiotherapy, Intensity modulated proton therapy (IMPT), Photon radiotherapy, Volumetric arc therapy (VMAT), Intensity modulated radiotherapy (IMRT), helical tomotherapy | Umeå University, Region Västerbotten | Anal Cancer Squamous Cell | 04/25 | 03/30 | | |
| Recruiting | N/A | 100 | Europe | Radiotherapy | Lund University Hospital | Tonsil Cancer | 01/28 | 01/28 | | |
| Rutegård, Martin |
| Recruiting | N/A | 100 | Europe | | Region Västerbotten | Rectal Cancer, Lymph Node Metastases | 12/21 | 12/23 | | |
| Recruiting | N/A | 20 | Europe | Defunctioning left-sided loop colostomy | Umeå University, Sunderby Hospital, Östersund Hospital, Sundsvall Hospital | Rectal Cancer | 12/24 | 12/25 | | |
| Not yet recruiting | N/A | 212 | NA | selective approach defunctioning stoma | Skane University Hospital, Umeå University, Lund University, Göteborg University, Ersta Hospital, Sweden, Copenhagen University Hospital at Herlev, Linkoeping University, Oslo University Hospital, Örebro University, Sweden | Rectal Cancer | 12/27 | 12/30 | | |
| Behndig, Anders |
| Active, not recruiting | N/A | 26 | Europe | PiXL | Umeå University, Glaukos Corporation | Myopia, Refractive Errors | 06/24 | 06/24 | | |
NCT04668924: Epi-on PiXL for the Treatment of Progressive Keratoconus. |
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| Active, not recruiting | N/A | 32 | Europe | Epi-on PiXL in high oxygen | Umeå University, Glaukos Corporation | Keratoconus, Corneal Crosslinking, Corneal Densitometry, Scheimpflug Photography, Corneal Disorder, Eye Diseases | 02/26 | 02/26 | | |
NCT03990506: Photorefractive Intrastromal Crosslinking (PiXL) for the Treatment of Progressive Keratoconus |
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| Completed | N/A | 32 | Europe | Epi-on PiXL, Epi-Off PiXL | Umeå University, Glaukos Corporation | Keratoconus, Corneal Crosslinking, Corneal Biomechanics, Corneal Densitometry, Scheimpflug Photography, Corneal Disease, Eye Diseases | 01/23 | 01/23 | | |
| Gustafsson, Maria |
NCT03671629: Clinical Pharmacist Intervention to Reduce Drug-related Readmissions Among Older People |
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| Recruiting | N/A | 700 | Europe | Enhanced clinical pharmacist service | Umeå University | Drug Use | 12/26 | 12/26 | | |
MTO, NCT05629936: Improving Medication Therapy Through a Digital Interdisciplinary Medicine Therapy Optimisation Model |
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| Active, not recruiting | N/A | 8 | Europe | Digital interdisciplinary intervention | Umeå University, Region Västerbotten | Drug Use | 12/25 | 12/26 | | |
| Sandberg, Camilla Sandberg |
NCT05454254: Effect of Muscle Strengthening Training in Adults with Fontan Circulation |
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| Completed | N/A | 20 | Europe | Individualised muscle strengthening exercise training protocol. | Umeå University | Congenital Heart Disease, Univentricular Heart | 11/23 | 11/23 | | |
| Recruiting | N/A | 90 | Europe | REMOTE-CR, Control | Umeå University | Heart Defects, Congenital | 12/23 | 02/24 | | |
NCT05339477: The Physical Activity Post Myocardial Infarction SWEDEHEART Prospective Cohort Study |
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| Recruiting | N/A | 4000 | Europe | Accelerometer measurement | Sahlgrenska University Hospital, Sweden, Gothia Forum - Center for Clinical Trial | Myocardial Infarction | 04/24 | 04/27 | | |
| Schwarzkopf, Ran |
| Recruiting | 4 | 412 | US | Dual mobility implant, Traditional, Single-bearing hip implant | Rush University Medical Center, New York University, Rothman Institute Orthopaedics, Keck School of Medicine of USC | Dislocation, Hip | 02/25 | 02/35 | | |
| Active, not recruiting | 4 | 404 | US | Dexamethasone 4mg, Group 1, Dexamethasone 8 Mg/mL Injectable Suspension, Group 2, Dexamethasone 16mg, Group 3 | Rush University Medical Center | Total Knee Arthroplasty | 01/25 | 02/25 | | |
| Recruiting | 4 | 322 | US | Dual Mobility Implant, Conventional, single-bearing implant | Rush University Medical Center, Rothman Institute Orthopaedics, Keck School of Medicine of USC, NYU Langone Health | Dislocation, Hip | 03/25 | 03/35 | | |
NCT03283878: Antibiotic Prophylaxis in Patients Undergoing Elective TKA- Multi-center Trial |
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| Active, not recruiting | 4 | 1770 | US | Cefazolin, Ancef | Duke University, American Association of Hip and Knee Surgeons, Orthopedic Research and Education Foundation | Arthropathy of Knee, Antibiotic Prophylaxis | 11/24 | 08/25 | | |
NCT06636669: Probiotics in the Prevention of Recurrent Prosthetic Joint Infection of the Hip and Knee |
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| Not yet recruiting | 4 | 152 | US | Probiotic, Culturelle, Standard of care | Boston Medical Center, American Association of Hip and Knee Surgeons | Prosthetic-joint Infection, Dysbiosis | 03/26 | 03/26 | | |
| Completed | 2 | 76 | US | VT-X7 Treatment System, Two-stage exchange arthroplasty, SOC Antibiotics, Experimental Antibiotics | Osteal Therapeutics, Inc. | Prosthetic-joint Infection | 05/24 | 10/24 | | |
NCT04075526: Vancomycin Powder and Dilute Povidone Iodine Lavage for Infection Prophylaxis in High Risk Total Joint Arthroplasty |
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| Active, not recruiting | 1 | 2129 | US | Povidone iodine, Vancomycin powder, Conventional | NYU Langone Health | Osteoarthritis | 01/24 | 01/26 | | |
NCT02276495: Can Single-Injection Adductor Canal Blocks Improve PostOp Pain Relief in Patients Undergoing Total Knee Arthroplasty? |
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| Completed | N/A | 55 | US | ACB Control - 20 ml saline injection for ACB, ACB Study - 20 ml 0.5% Ropivacaine for Adductor Canal Block, Local infiltration - 100 mLs of a solution containing: Ropivacaine + Epinephrine + Ketorolac + Clonidine + 0.9% Normal saline | University of California, Irvine | Pain Management | 06/20 | 09/24 | | |
NCT04403919: Knotless Suture in Revision Total Joint Arthroplasty |
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| Completed | N/A | 81 | US | Conventional Closure: Knee, Barbed suture closure: Knee, Conventional Closure: Hip, Barbed suture closure: Hip | NYU Langone Health | Arthroplasty | 06/23 | 06/23 | | |
NCT04210284: Oral Nutritional Optimization in Total Joint Arthroplasty |
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| Recruiting | N/A | 372 | US | Ensure | NYU Langone Health | Osteoarthritis | 07/25 | 12/25 | | |
NCT05197036: A Global Clinical Study Investigating the Safety and Effectiveness of Smith and Nephew's Porous Knee System in Patients Who Need a Total Knee Replacement Due to Degenerative Arthritis, Post-traumatic Arthritis or Inflammatory Arthritis |
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| Active, not recruiting | N/A | 299 | Europe, Canada, US, RoW | Total Knee Arthroplasty, Total Knee Replacement | Smith & Nephew, Inc. | Osteoarthritis, Post-traumatic Arthritis, Rheumatoid Arthritis | 12/25 | 12/28 | | |
| Active, not recruiting | N/A | 47 | Europe, Canada, US, RoW | LEGION Hinge Knee System, LEGION HK | Smith & Nephew, Inc. | Knee Arthroplasty, Total | 12/27 | 08/28 | | |
| Not yet recruiting | N/A | 192 | US | Core Decompression, Core Decompression Procedure with Autologous Bone Marrow Aspirate Concentrate | Johns Hopkins University, Stanford University, Sinai Hospital of Baltimore, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Osteonecrosis of the Femoral Head, Avascular Necrosis of the Femoral Head | 04/28 | 08/28 | | |
| Active, not recruiting | N/A | 177 | Canada, US, RoW | Primary Total Hip Arthroplasty, Revision Total Hip Arthroplasty | Smith & Nephew, Inc. | Advanced Degeneration of the Hip Joint, Revision of the Hip Joint | 12/26 | 01/35 | | |
| Coordinator, Research |
| Recruiting | 4 | 292 | US | Amnion-Intermediate-Chorion, AIC, Amnion-Chorion-Amnion, ACA, Standard of Care, SOC | Cellution Biologics, SerenaGroup, Inc., LifeCell | Diabetic Foot Ulcer, Venous Leg Ulcer | 12/26 | 07/27 | | |
| Recruiting | 4 | 2650 | US | Zoledronic Acid 5Mg/Bag 100Ml Inj, Reclast, Placebo | California Pacific Medical Center Research Institute, National Institute on Aging (NIA), University of California, San Francisco, Duke University, University of Pittsburgh, Parkinson's Foundation | Parkinson Disease, Osteoporosis, Parkinsonism, Parkinson's Disease and Parkinsonism, Atypical Parkinsonism, Progressive Supranuclear Palsy, Multiple System Atrophy, Vascular Parkinsonism, Dementia With Lewy Bodies | 10/25 | 10/25 | | |
NCT05078827: Therapeutic Equivalence of Fluorouracil Cream, 5% Compared With Fluorouracil 5% Topical Cream of MylanPharmaceuticals Inc., U.S.A in the Treatment of Actinic Keratosis |
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| Completed | 3 | 458 | US | Test Product (A): Fluorouracil Cream, 5% topical cream, Experimental, Reference Product (B): Fluorouracil 5% Topical Cream of Mylan Pharmaceuticals Inc., Morgantown, WV 26505 U.S.A., Active Comparator, Placebo Product (C): Test vehicle cream for fluorouracil 5% of Encube Ethicals Pvt. Ltd., India, Placebo Comparator | Encube Ethicals Pvt. Ltd., CBCC Global Research | Actinic Keratoses | 11/22 | 12/22 | | |
| Completed | 3 | 558 | US | ReMMi-D Digital Therapeutic | Click Therapeutics, Inc. | Migraine, Episodic Migraine, Headache, Headache, Migraine | 05/24 | 05/24 | | |
OPERA-T, NCT05238116 / 2021-004554-32: Safety and Efficacy of PC945 (Opelconazole) in Combination With Other Antifungal Therapy for the Treatment of Refractory Invasive Pulmonary Aspergillosis ( Study) |
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| Recruiting | 3 | 123 | Europe, Canada, US, RoW | PC945, Placebo | Pulmocide Ltd | Refractory IPA | 03/26 | 04/26 | | |
NCT06004388: Study of Two Digital Therapeutics for the Prevention of Episodic Migraine Receiving CGRP Therapy (ReMMiD-C) |
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| Completed | 3 | 110 | US | Click Digital Therapeutic | Click Therapeutics, Inc. | Migraine, Episodic Migraine, Headache, Headache, Migraine | 05/24 | 06/24 | | |
SKOAP, NCT04504812: A Sequenced Strategy for Improving Outcomes in People With Knee Osteoarthritis Pain |
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| Active, not recruiting | 3 | 1800 | US | Duloxetine, Cymbalta, Intra-Articular Injection, Nerve Procedure with long acting blocks, Nerve Procedure with nerve ablation, Pain Coping Skills Training, Best Practices | Johns Hopkins University, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Knee Osteoarthritis | 03/25 | 03/25 | | |
CONVOKE, NCT05838625: Study of Two Digital Therapeutics for the Treatment of Experiential Negative Symptoms of Schizophrenia |
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| Recruiting | 3 | 432 | US | Digital Therapeutic | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia | 06/25 | 07/25 | | |
NCT06067984: An Extension Study of a Second Course of a Digital Therapeutic for the Treatment of Experiential Negative Symptoms of Schizophrenia |
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| Active, not recruiting | 3 | 75 | US | Study App | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia, Negative Symptoms in Schizophrenia | 04/25 | 05/25 | | |
| Active, not recruiting | 2/3 | 1500 | US | ABBV-CLS-7262, DNL343 | Merit E. Cudkowicz, MD, Massachusetts General Hospital | Amyotrophic Lateral Sclerosis | 07/25 | 04/26 | | |
NCT06365437: A Dose Escalation Study of TCD601 Compared to ATG in de Novo Renal Transplantation |
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| Completed | 2 | 33 | Europe | TCD601, Siplizumab, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG | ITB-Med LLC | Kidney Transplantation | 12/24 | 12/24 | | |
| Recruiting | 2 | 25 | Europe, Canada, Japan, US, RoW | nedosiran, DCR-PHXC | Dicerna Pharmaceuticals, Inc., a Novo Nordisk company | Primary Hyperoxaluria, Primary Hyperoxaluria Type 1, Primary Hyperoxaluria Type 2, Primary Hyperoxaluria Type 3 | 12/24 | 12/24 | | |
NCT03651700: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Chronic Aphasia |
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| Completed | 2 | 86 | US | Active TMS, Sham TMS, CILT, Constraint Induced Language Therapy | H. Branch Coslett, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD) | Aphasia | 08/24 | 08/24 | | |
CHASE, NCT05727878: Trial to Evaluate Safety and Efficacy of KPI-012 Ophthalmic Solution in Participants With PCED |
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| Recruiting | 2 | 90 | US, RoW | KPI-012, KPI-012 Vehicle | Combangio, Inc, Kala Pharmaceuticals, Inc. | Persistent Corneal Epithelial Defect | 03/25 | 10/25 | | |
NCT05733546: A Phase II, Multicentre, Randomised, Double-blind, Controlled Study to Investigate the Safety, Tolerability, Pharmacokinetics, and Efficacy of COMP360 in Participants With Recurrent Major Depressive Disorder |
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| Recruiting | 2 | 102 | US | Psilocybin, COMP360 | COMPASS Pathways | Major Depressive Disorder | 10/24 | 11/24 | | |
NCT04270175: Daratumumab, Pomalidomide, and Dexamethasone (DPd) in Relapsed/Refractory Light Chain Amyloidosis Patients Previously Exposed to Daratumumab |
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| Recruiting | 2 | 21 | US | Daratumumab SC, Faspro, Pomalidomide, Dexamethasone | Weill Medical College of Cornell University, Janssen Scientific Affairs, LLC | Amyloid, AL Amyloidosis, Refractory AL Amyloidosis | 12/25 | 12/29 | | |
NCT04803058: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PERSPECTIVE) |
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| Recruiting | 2 | 18 | US, RoW | TCD601 | ITB-Med LLC | Kidney Transplantation | 03/27 | 03/30 | | |
| Not yet recruiting | 2 | 20 | US | Sodium Thiosulfate (STS) | Robyn T. Domsic, MD, MPH, National Institute of Arthritis and Musculoskeletal and Skin Diseases (NIAMS) | Systemic Sclerosis (SSc), Dermatomyositis, Mixed Connective Tissue Disease (MCTD), Calcinosis | 05/25 | 11/25 | | |
| Active, not recruiting | 2 | 96 | Europe | TCD601, Placebo | ITB-Med LLC | Diabetes Mellitus, Type 1 | 01/25 | 01/25 | | |
| Not yet recruiting | 2 | 30 | Canada | AMT-143 hydrogel containing containing ropivacaine, AMT-143, Ropivacaine, Placebo | AmacaThera Inc. | Hernia, Hernia, Abdominal | 03/26 | 05/26 | | |
| Recruiting | 2 | 90 | US | TCD601, siplizumab, belatacept, ATG, antithymocyte globulin, TAC, tacrolimus, MPA, mycophenolic acid, Corticosteroids | ITB-Med LLC | Renal Transplantation | 07/25 | 10/26 | | |
NCT04311632: A Dose Escalation Study in de Novo Renal Transplantation |
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| Completed | 2 | 13 | US | TCD601, Tacrolimus (TAC), Corticosteroids (CS), Mycophenolate Mofetil (MMF), ATG | ITB-Med LLC | Kidney Transplantation | 10/23 | 10/23 | | |
NCT04464980: Optimizing Retention, Duration and Discontinuation Strategies for Opioid Use Disorder Pharmacotherapy (RDD) |
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| Recruiting | 2 | 2190 | US | SL-BUP, sublingual buprenorphine, Suboxone, XR-BUP, extended-release buprenorphine, CAM2038, Brixadi, XR-NTX, extended-release naltrexone, Vivitrol, MM, MMR, MMD | NYU Langone Health, New York State Psychiatric Institute, Columbia University, Harvard Medical School (HMS and HSDM), Mclean Hospital, National Institute on Drug Abuse (NIDA), The Emmes Company, LLC | Opioid Use Disorder (OUD) | 07/26 | 12/26 | | |
NCT04803006: A Study of TCD601 in the Induction of Tolerance in Renal Transplantation (PANORAMA) |
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| Recruiting | 2 | 18 | US | TCD601 | ITB-Med LLC | Kidney Transplantation | 07/27 | 07/30 | | |
NCT04892251: Ketamine Assisted Psychotherapy for Opioid Use Disorder |
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| Recruiting | 1/2 | 60 | US | MORE+KAP, MORE | University of Utah | Opioid-use Disorder | 12/23 | 05/24 | | |
NCT04482179: Transcranial Magnetic Stimulation and Constraint Induced Language Therapy for Alzheimer Disease |
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| Completed | 1 | 23 | US | Active TMS, CILT, Constraint Induced Language Therapy, Sham TMS | University of Pennsylvania, National Institutes of Health (NIH), National Institute on Deafness and Other Communication Disorders (NIDCD) | Alzheimer Disease | 08/24 | 08/24 | | |
AURORA, NCT06453668: A Study of TCD601 (Siplizumab) in Newly Diagnosed Adult Amyotrophic Lateral Sclerosis (ALS) Patients |
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| Active, not recruiting | 1 | 48 | Europe | TCD601, siplizumab | ITB-Med LLC | ALS | 11/26 | 11/26 | | |
| Recruiting | 1 | 15 | US | PBA-0405, PB004.22.0405.aF | Pure Biologics S.A., Presage Biosciences | Head and Neck Squamous Cell Carcinoma, Soft Tissue Sarcoma Adult, Triple Negative Breast Cancer | 03/25 | 03/25 | | |
MST01-AZN-05, NCT06366451: PBI-MST-01 (NCT04541108) Substudy AZN-05: Intratumoral Microdosing of Rilvegostomig, Volrustomig, and Sabestomig in HNSCC |
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| Recruiting | 1 | 15 | US | Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, Pembrolizumab, Keytruda, MK-3475 | Presage Biosciences, AstraZeneca | Head and Neck Squamous Cell Carcinoma | 12/24 | 03/25 | | |
| Recruiting | 1 | 155 | US, RoW | OP-1250, Ribociclib, KISQALI®, Alpelisib, PIQRAY®, Everolimus | Olema Pharmaceuticals, Inc., Novartis | Metastatic Breast Cancer, Advanced Breast Cancer, ER-positive Breast Cancer, HER2-negative Breast Cancer, Breast Cancer | 05/26 | 06/26 | | |
NCT06798454: Single Ascending Dose Study to Evaluate Safety Tolerability, Pharmacokinetics, and Pharmacodynamics of PVT201 in Healthy Subjects and Patients (PBC/PSC) |
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| Recruiting | 1 | 30 | RoW | PVT201, Navacim, Placebo, normal saline, 0.9% NaCl | Parvus Therapeutics, Inc., Avance Clinical Pty Ltd. | Primary Biliary Cholangitis (PBC) | 02/25 | 02/25 | | |
NCT04541108: Phase 0 Master Protocol for CIVO Intratumoral Microdosing of Anti-Cancer Therapies |
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| Recruiting | 1 | 15 | US | Rilvegostomig, AZD2936, Volrustomig, MEDI5752, Sabestomig, AZD7789, Pembrolizumab, Keytruda, MK-3475 | Presage Biosciences, Merck Sharp & Dohme LLC | Solid Tumor | 12/31 | 12/31 | | |
NCT06802328: Treatment Protocol: Intermediate-Size Patient Population Expanded Access |
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| Available | N/A | | US | Foralumab TZLS-401 50 µg | Tiziana Life Sciences LTD | Non-Active Secondary Progressive Multiple Sclerosis | | | | |
NCT06129084: A Study to Compare the Results of FGFR Testing by Either CtDNA Blood Testing or Standard Tumor Tissue Testing |
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| Recruiting | N/A | 260 | Canada | FGFR Testing | Bernie Eigl, Vancouver Prostate Centre, Lady Davis Institute, Bladder Cancer Canada | Metastatic Bladder Cancer, Metastatic Urothelial Carcinoma | 03/25 | 05/25 | | |
| Completed | N/A | 199 | US | Cigarette flavor type, Experimental cigarette smoking | University of Oklahoma | Smoking, Cigarette | 12/22 | 01/23 | | |
NCT03869463: Computerized Cognitive Training in Young Adults With Depression |
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| Terminated | N/A | 28 | US | Computerized Cognitive Training, Control | Queens College, The City University of New York | Depressive Symptoms | 03/23 | 03/23 | | |
NCT03495011: MRI Characterization of Mammographically Detected DCIS |
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| Active, not recruiting | N/A | 122 | US | Breast MRI, Laboratory Biomarker Analysis, Oncotype Dx | University of Washington, National Cancer Institute (NCI), National Institutes of Health (NIH) | Breast Cancer, Stage 0 | 04/23 | 04/32 | | |
| Recruiting | N/A | 35 | US | MRI, blood draw, Clinical assessments | University of Vermont, National Institute of General Medical Sciences (NIGMS) | Stroke, Acute, Gait, Hemiplegic | 05/23 | 05/23 | | |
NCT04902339: Near-infrared Spectroscopy-based Neurofeedback as Adjunct to Mindfulness-Oriented Recovery Enhancement in Persons With Chronic Pain |
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| Recruiting | N/A | 75 | US | Mindfulness-Oriented Recovery Enhancement, Neurofeedback, Supportive Psychotherapy | University of Utah | Chronic Pain Syndrome, Opioid Use | 05/23 | 08/23 | | |
NCT04088773: Biomarkers of Intestinal Fibrosis in Small Bowel Crohn's Disease |
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| Active, not recruiting | N/A | 232 | US | blood biomarkers, stool biomarkers, MRI imaging | Children's Hospital Medical Center, Cincinnati, The Leona M. and Harry B. Helmsley Charitable Trust | Crohn Disease | 09/23 | 09/24 | | |
NCT06136936: A Study to Evaluate the Overall Effects of Treatment With Abbreviated CT-156 in People With Schizophrenia |
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| Completed | N/A | 53 | US | CT-156-C-001 | Click Therapeutics, Inc., Boehringer Ingelheim | Schizophrenia | 01/24 | 02/24 | | |
| Recruiting | N/A | 20 | US | Prototypes of breast shield and Freedom Double Electric Breast Pump | Momtech Inc. | Healthy, Breast Pumping | 09/24 | 11/24 | | |
NCT06136923: An Exploratory Study to Evaluate Attention Biases in Adults With Multiple Sclerosis, Breast Cancer, and Lung Cancer |
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| Completed | N/A | 194 | US | CT-100-D-004-A, CT-100-D-004-B | Click Therapeutics, Inc. | Multiple Sclerosis, Lung Cancer, Breast Cancer | 04/24 | 05/24 | | |
NCT05465395: Upper Cervical and Thoracic Chiropractic Adjustment |
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| Suspended | N/A | 40 | US | Upper Cervical Adjustemnt, Thoracic Adjustemnt | Life University | Stress | 11/23 | 11/23 | | |
| Completed | N/A | 314 | US | FemaSeed Localized Directional Insemination | Femasys Inc. | Infertility, Male Factor | 12/23 | 04/24 | | |
CT-100-D-003, NCT06275659: An Exploratory Study to Evaluate a Digital Intervention to Disrupt Scratching in Atopic Dermatitis and Psoriasis |
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| Active, not recruiting | N/A | 120 | US | CT-100-004-A, CT-100-004-B | Click Therapeutics, Inc. | Psoriasis, Atopic Dermatitis | 02/24 | 03/24 | | |
NCT05617300: Mindfulness-based Dementia Care Partner Program to Reduce Depressive Symptoms |
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| Completed | N/A | 130 | US | Mindfulness-Based Dementia Caregiving | HealthPartners Institute | Dementia | 12/23 | 03/24 | | |
NCT04685044: Testing a 32-channel Transmit/Receive MRI Head Array |
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| Active, not recruiting | N/A | 15 | Canada | IH 1Tx32Rx Head Array | Lawson Health Research Institute | Magnetic Resonance Imaging | 12/23 | 12/23 | | |
