| Leung, Wai K |
NCT05133544: Endocuff With or Without AI-assisted Colonoscopy |
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| Recruiting | N/A | 656 | RoW | Endocuff with AI, AI alone | The University of Hong Kong | Colonic Adenoma, Colonic Polyp, Colonic Cancer | 12/23 | 02/24 | | |
JCJoyAge2, NCT04863300: Collaborative Stepped-Care and Productive Ageing Program for Older People With Depressive Symptoms |
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| Recruiting | N/A | 3000 | RoW | Collaborative stepped care and peer support | The University of Hong Kong, Aberdeen Kai-fong Welfare Association Social Service, Caritas Medical Centre, Hong Kong, Christian Family Service Centre, Haven of Hope Hospital, Hong Kong Christian Service, Hong Kong Sheng Kung Hui Lady MacLehose Centre, Hong Kong Sheng Kung Hui Welfare Council Limited, Hong Kong Young Women's Christian Association (YWCA), New Life Psychiatric Rehabilitation Association, St James' Settlement (Hong Kong), The Hong Kong Society for the Aged, The Mental Health Association of Hong Kong, The Neighbourhood Advice-Action Council, Tung Wah Group of Hospitals | Depressive Symptoms | 12/23 | 06/24 | | |
NCT06482333: Timing of Resumption of Direct Oral Anticoagulants Following Polypectomy |
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| Recruiting | N/A | 194 | RoW | Time for resumption of DOAC | The University of Hong Kong | Postpolypectomy Bleeding | 08/26 | 12/26 | | |
| Yau, Thomas |
PANOVA-3, NCT03377491: Effect of Tumor Treating Fields (TTFields, 150 kHz) as Front-Line Treatment of Locally-advanced Pancreatic Adenocarcinoma Concomitant With Gemcitabine and Nab-paclitaxel |
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| Completed | 3 | 571 | Europe, Canada, US, RoW | NovoTTF-200T, TTFields, Gemcitabine, nab paclitaxel | NovoCure Ltd. | Pancreas Adenocarcinoma | 10/24 | 10/24 | | |
| Active, not recruiting | 2 | 240 | Europe, US, RoW | CAB-AXL-ADC, BA3011, PD-1 inhibitor | BioAtla, Inc., BioAtla Inc. | Non-Small-Cell Lung Cancer | 08/25 | 08/25 | | |
| Active, not recruiting | 1/2 | 300 | US, RoW | CAB-AXL-ADC, PD-1 inhibitor | BioAtla, Inc. | Undifferentiated Pleomorphic Sarcoma, Myxofibrosarcoma | 01/25 | 01/25 | | |
MYCHELANGELO I, NCT05497453: A Phase 1/2 Study to Evaluate OTX-2002 in Patients with Hepatocellular Carcinoma and Other Solid Tumor Types Known for Association with the MYC Oncogene |
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| Recruiting | 1/2 | 190 | US, RoW | OTX-2002, Tyrosine kinase inhibitor One, Tyrosine kinase inhibitor Two, Checkpoint Inhibitor, Immune | Omega Therapeutics | Hepatocellular Carcinoma, Solid Tumor, Hepatocellular Carcinoma Non-resectable, Hepatocellular Carcinoma Recurrent, Hepatocellular Cancer, Liver Cancer, Liver, Cancer Of, Non-Resectable | 06/25 | 12/28 | | |
| Completed | 1/2 | 132 | Europe, US, RoW | CAB-ROR2-ADC, BA3021, PD-1 inhibitor | BioAtla, Inc., BioAtla Inc. | Non Small Cell Lung Cancer, Triple Negative Breast Cancer, Melanoma, Head and Neck Cancer | 12/24 | 12/24 | | |
| Recruiting | 1/2 | 500 | Europe, Canada, Japan, US, RoW | Oral repotrectinib (TPX-0005), repotrectinib | Turning Point Therapeutics, Inc., Zai Lab (Shanghai) Co., Ltd. | Locally Advanced Solid Tumors, Metastatic Solid Tumors | 02/28 | 02/28 | | |
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NCT05226468: An Early Phase Study of NEI-01 in Patients With Solid Tumors or Acute Myeloid Leukemia |
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| Active, not recruiting | 1 | 24 | RoW | NEI-01 | New Epsilon Innovation Limited | Advanced Solid Tumor, Relapsed AML, Refractory AML | 01/24 | 07/24 | | |
| Terminated | 1 | 29 | Europe, US, RoW | PBI-200 | Pyramid Biosciences, Pyramid Biosciences, Inc., Pyramid Biosciences | Solid Tumor, Adult, Brain Tumor, Primary, Desmoplastic Small Round Cell Tumor | 07/23 | 07/23 | | |
| Hung, Ivan FN |
NCT04143451: Intradermal Influenza Vaccine With Topical Imiquimod in Elderly and Chronic Illness Patients |
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| Recruiting | 3 | 4000 | RoW | Vaxigrip tetra, Fluzone high-dose, Aldara 5% Topical Cream, Aqueous cream BP | The University of Hong Kong | Influenza | 09/22 | 03/23 | | |
NCT05382871: Sequential Immunization of Two Doses of Inactivated COVID-19 Vaccine (Omicron) in Vaccinated Population Aged 18 Years and Above |
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| Active, not recruiting | 3 | 1804 | RoW | BIBP Omicron Inactivated COVID-19 vaccine (Vero Cell), WIBP Omicron Inactivated COVID-19 vaccine (Vero Cell), COVID-19 Vaccine (Vero Cell), Inactivated | China National Biotec Group Company Limited, Beijing Institute of Biological Products Co Ltd., Wuhan Institute of Biological Products Co., Ltd, The University of Hong Kong | COVID-19 | 07/23 | 03/24 | | |
NCT04900415: Olfactory and Neurosensory Rehabilitation in COVID-19-related Olfactory Dysfunction |
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| Recruiting | 2 | 25 | RoW | Vitamin A, Electronic portable aromatic rehabilitation (EPAR) diffuser | Ivan FN Hung MD, Pamela Youde Nethersole Eastern Hospital | Coronavirus Disease 2019 | 03/21 | 06/21 | | |
NCT04465695: Dual Therapy With Interferon Beta-1b and Clofazimine for COVID-19 |
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| Recruiting | 2 | 81 | RoW | Interferon beta-1b, Clofazimine | The University of Hong Kong | COVID-19 | 06/21 | 09/21 | | |
| Recruiting | 2 | 100 | RoW | Interferon beta-1b, Remdesivir | The University of Hong Kong | Covid19 | 07/21 | 09/21 | | |
| Recruiting | 2 | 96 | RoW | Interferon beta-1b, Ribavirin | The University of Hong Kong, Hospital Authority, Hong Kong | Covid19 | 07/22 | 08/22 | | |
NCT05736913: Intradermal COVID-19 Vaccination in the Immunocompromised |
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| Recruiting | 2 | 130 | RoW | ID BNT162b2 vaccine, IM BNT162b2 vaccine | The University of Hong Kong | COVID-19 | 03/23 | 06/23 | | |
NCT05200741: To Evaluate Safety & Immunogenicity of DelNS1-2019-nCoV-RBD-OPT1 for COVID-19 in Healthy Adults Received 2 Doses of BNT162b2 |
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| Recruiting | 2 | 150 | RoW | DelNS1-2019-nCoV-RBD-OPT1, Matching placebo | The University of Hong Kong | Covid19 | 02/24 | 02/24 | | |
NCT05102643: A Study to Evaluate Safety & Immunogenicity of SARS-CoV-2 DNA Vaccine Delivered Intramuscularly Followed by Electroporation for COVID-19 |
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| Recruiting | 1 | 30 | RoW | SARS-CoV-2 DNA Vaccine, Matching placebo | The University of Hong Kong, Immuno Cure 3 Limited | Covid19 | 06/22 | 12/22 | | |
NCT04809389: A Study to Evaluate Safety and Immunogenicity of DelNS1-nCoV-RBD LAIV for COVID-19 |
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| Active, not recruiting | 1 | 115 | RoW | DelNS1-nCoV-RBD LAIV, Matching placebo | The University of Hong Kong | Covid19 | 09/22 | 09/22 | | |
| To, Kelvin |
NCT04143451: Intradermal Influenza Vaccine With Topical Imiquimod in Elderly and Chronic Illness Patients |
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| Recruiting | 3 | 4000 | RoW | Vaxigrip tetra, Fluzone high-dose, Aldara 5% Topical Cream, Aqueous cream BP | The University of Hong Kong | Influenza | 09/22 | 03/23 | | |
| Recruiting | 2 | 96 | RoW | Interferon beta-1b, Ribavirin | The University of Hong Kong, Hospital Authority, Hong Kong | Covid19 | 07/22 | 08/22 | | |
| Foo, Dominic CC |
NCT04568226: The Effect of Metacognition-based, Manualized Intervention on Fear of Cancer Recurrence |
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| Completed | N/A | 177 | RoW | ConquerFear Intervention, Active control: Basic Cancer Care | The University of Hong Kong, Research Grants Council, Hong Kong | Fear of Cancer Recurrence | 09/23 | 02/24 | | |
NCT06207006: E-intervention on Subclinical Fear of Cancer Recurrence |
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| Recruiting | N/A | 48 | RoW | eConquerFear-HK, Basic Cancer Care | The University of Hong Kong, Health and Medical Research Fund | Cancer, Psychooncology, Fear of Cancer Recurrence | 06/25 | 09/25 | | |
NCT05534386: A Self-management Based Survivorship Intervention for Chinese Cancer Survivors |
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| Recruiting | N/A | 366 | RoW | Cancer survivorship care intervention, Step-up targeted personalized intervention, First stage control intervention, Second stage control intervention | The University of Hong Kong | Physical Symptom Distress, Weight Management, Neoplasms | 12/25 | 12/26 | | |
NCT05949996: Evaluation of a Program for Routine Implementation of Symptom Distress Screening and Referral in Cancer Care |
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| Recruiting | N/A | 2772 | RoW | A nurse-led symptom distress screening program | The University of Hong Kong, Health and Medical Research Fund | Neoplasms | 09/25 | 09/25 | | |
NCT05679518: Managing Fear of Cancer Progression Metacognition-based Vs Supportive-expressive Based Approaches |
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| Recruiting | N/A | 261 | RoW | ConquerFear intervention, CALM intervention, Basic Cancer Care | The University of Hong Kong, Research Grants Council, Hong Kong | Advanced or Metastatic Cancer, Fear of Cancer Progression, Metacognition-based Intervention, Supportive-expressive Based Intervention, Psychooncology | 12/25 | 06/26 | | |
| Leung, Anskar |
NCT03135054: Combination of Quizartinib and Omacetaxine Mepesuccinate for AML Carrying FLT3-ITD |
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| Active, not recruiting | 2 | 40 | RoW | Quizartinib, AC220, Omacetaxine Mepesuccinate Injection, homoharringtonine | The University of Hong Kong | AML, FLT3-ITD Mutation | 10/20 | 10/21 | | |
NCT03080766: The Use of Decitabine as Induction Therapy for Acute Myeloid Leukemia With Complex and/or Monosomal Karyotype |
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| Recruiting | 2 | 20 | RoW | Decitabine, Dacogen | The University of Hong Kong, Janssen, LP | Acute Myeloid Leukemia, Complex Karyotype | 09/21 | 12/21 | | |
TWT-202, NCT04730258: A Study of CFI-400945 With or Without Azacitidine in Patients With AML, MDS or CMML |
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| Recruiting | 1/2 | 72 | Canada, US, RoW | CFI-400945, CFI-400945 fumarate, 945, 400945, Azacitidine | Treadwell Therapeutics, Inc | Acute Myeloid Leukemia, Myelodysplastic Syndromes, Chronic Myelomonocytic Leukemia, AML, MDS, CMML | 01/26 | 01/26 | | |
| Siu, David Chung-Wah |
| Active, not recruiting | 4 | 30 | RoW | Dapagliflozin | The University of Hong Kong | Type2 Diabetes, Heart Failure With Reduced Ejection Fraction | 03/21 | 09/21 | | |
NCT04045093: Dabigatran for Mitral Stenosis Atrial Fibrillation |
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| Recruiting | 4 | 370 | RoW | Dabigatran etexilate, Pradaxa, Warfarin | The University of Hong Kong | Atrial Fibrillation, Mitral Stenosis | 09/26 | 09/27 | | |
| Terminated | 1/2 | 5 | RoW | YQ23, Matching placebo | New Beta Innovation Limited | Critical Limb Ischemia | 08/23 | 08/23 | | |
NCT05043649: Camsirubicin + Pegfilgrastim to Determine MTD in ASTS |
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| Terminated | 1 | 14 | US | Camsirubicin | Monopar Therapeutics | Advanced Soft-tissue Sarcoma | 10/23 | 05/24 | | |
| Recruiting | N/A | 1800 | RoW | | The University of Hong Kong | Connective Tissue Diseases, Systemic Sclerosis, Systemic Lupus Erythematosus | 08/23 | 12/23 | | |
| Center, Call |
NCT06487364: Determination of the Minimal Detectable Change of the Parkinson's Disease Questionnaire-8 |
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| Recruiting | N/A | 39 | RoW | Rehabilitation | Emre Şenocak | Parkinson Disease | 01/25 | 01/25 | | |
NCT06482502: Validity of the 6-Minute Pegboard and Ring Test in Parkinson's Patients |
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| Recruiting | N/A | 34 | RoW | | Emre Şenocak | Parkinson Disease | 12/24 | 12/24 | | |
| Recruiting | N/A | 30 | RoW | Walking and Remembering Test | Emre Şenocak | Healthy Individuals | 01/25 | 01/25 | | |
| Siu, Chung-Wah David |
| Active, not recruiting | N/A | 876 | RoW | Home-based remote heart failure management, Home-based physiological parameter recording only | The University of Hong Kong, Chinese University of Hong Kong, Novartis Pharmaceuticals, Biofourmis Singapore Pte Ltd. | Heart Failure With Reduced Ejection Fraction | 04/23 | 04/23 | | |
HUA-TUO, NCT04523649: Home-Based SolUtion for Remote Atrial Fibrillation Screening to PrevenT RecUrrence StrOke ( AF Trial) |
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| Not yet recruiting | N/A | 1740 | NA | Remote atrial fibrillation screening with handheld single lead ECG recorder | The University of Hong Kong | Stroke, Cardiovascular | 12/24 | 12/25 | | |
| Not yet recruiting | N/A | 344 | RoW | Remote integrated post-MI management system, Holter monitoring system HC3A250 (BISA Technologies (Hong Kong) Limited, Hong Kong SAR, China), Single-lead electrocardiogram (ECG) recorder (Comfit Healthcare Devices Limited, Hong Kong SAR, China) | The University of Hong Kong | Myocardial Infarction | 06/25 | 06/26 | | |
| Chow, Wing Sun |
NCT05102149: Study to Evaluate the Safety and Efficacy of PB-201 in Treatment-naive Patients With Type 2 Diabetes Mellitus |
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| Recruiting | 3 | 672 | RoW | PB-201, Vildagliptin, PB-201 matched placebo, Vildagliptin matched placebo | PegBio Co., Ltd. | Type 2 Diabetes Mellitus (T2DM) | 11/23 | 04/25 | | |
NCT06528132: Social Worker-led Mindfulness-based Intervention for Older People |
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| Recruiting | N/A | 207 | RoW | Mindfulness-based intervention (MBI) (enhanced with peer supporters), Experimental: social worker-led MBI (without peer supporters) | The University of Hong Kong, The Hong Kong Jockey Club Charities Trust, Christian Family Service Centre, The Mental Health Association of Hong Kong, The Salvation Army, Hong Kong and Macau Command, Haven of Hope Hospital, Hong Kong Sheng Kung Hui, Tung Wah Group of Hospitals, Aberdeen Kai-fong Welfare Association, Hong Kong Society for the Aged, The Neighbourhood Advice-Action Council | Depressive Symptoms | 03/26 | 03/26 | | |
