Washington University in St. Louis
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 88 Trials 
143 Trials

   

Trial + Data / EventsStatusPhNRegionInterventionsSponsorConditionsPrimary complStudy compl
Castro, Mario
NCT04203797 / 2019-002742-20: A Study to Evaluate the Effect of Dupilumab on Exercise Capacity in Adult Patients With Asthma

Completed
4
40
Europe, US
dupilumab, Dupixent®, SAR231893, Matching placebo
Regeneron Pharmaceuticals
Asthma
07/23
07/23
RELIANCE, NCT04069312: Roflumilast or Azithromycin to Prevent COPD Exacerbations

Recruiting
4
1250
US
Roflumilast, Daliresp, Azithromycin, Zithromax
Johns Hopkins University, Patient-Centered Outcomes Research Institute, University of Illinois at Chicago
Chronic Obstructive Pulmonary Disease Severe, Chronic Bronchitis
03/26
05/26
CHINOOK, NCT03953300 / 2018-003391-13: Benralizumab Airway Remodeling Study in Severe Eosinophilic Asthmatics

Recruiting
4
81
Europe, Canada, US
Benralizumab, Placebo
AstraZeneca
Asthma
09/26
09/26
RECOVER-AUTO, NCT06305780: NOMIC Platform Protocol

Recruiting
2
380
US
IVIG + Coordinated Care, IVIG Placebo + Coordinated Care, Ivabradine + Coordinated Care, Ivabradine Placebo + Coordinated Care, IVIG + Usual Care, IVIG Placebo + Usual Care, Ivabradine + Usual Care, Ivabradine Placebo + Usual Care
Kanecia Obie Zimmerman
Long COVID, Long Covid19, Long Covid-19
12/25
03/26
RECOVER-VITAL, NCT05595369: Platform Protocol to Measure the Effects of Antiviral Therapies on Long COVID Symptoms

Active, not recruiting
2
964
US
Experimental: Paxlovid 25 day dosing, Experimental: Paxlovid 15 day dosing, Placebo Comparator: Control
Kanecia Obie Zimmerman
Long COVID, Long Covid19
08/24
03/25
NCT04129931: PrecISE (Precision Interventions for Severe and/or Exacerbation-Prone Asthma) Network Study

Active, not recruiting
2
395
US
MCT, Breathe Better Diet (BBD), Clazakizumab, Anti-interleukin 6 monoclonal antibody, Anti-IL-6 mAb, BMS-945429, ALD518, Broncho-Vaxom, OM-85 BV VEGETAL, Imatinib Mesylate, Gleevec, Zoleta, Glivec, Ziatir, Cavosonstat, N91115, Placebo
University of North Carolina, Chapel Hill, National Heart, Lung, and Blood Institute (NHLBI)
Asthma
12/24
12/24
NCT05707507: Implementation of an Outpatient Parenteral Antimicrobial Therapy Program

Recruiting
N/A
40
RoW
Place of treatment
Hospital Universitario Dr. Jose E. Gonzalez
Outpatient
01/24
01/24
DLP-LHC, NCT06177717: Deep Functional Phenotyping of the ALA Lung Health Cohort

Recruiting
N/A
1000
US
Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI), American Lung Association, University of Vermont
Lung Diseases
07/26
07/26
RheSolve, NCT04677465: Clinical Study of the RheOx Bronchial Rheoplasty System in Treating the Symptoms of Chronic Bronchitis

Active, not recruiting
N/A
270
Europe, US
RheOx Bronchial Rheoplasty, Sham Procedure
Gala Therapeutics, Inc.
Chronic Bronchitis
05/24
10/25
NCT04543461: American Lung Association (ALA) Lung Health Cohort

Recruiting
N/A
4000
US
Johns Hopkins University, National Heart, Lung, and Blood Institute (NHLBI), American Lung Association, Stanford University
Lung Diseases
09/26
09/26
NCT05172024: Understanding the Long-term Impact of COVID-19 in Adults (RECOVER)

Active, not recruiting
N/A
15178
US
NYU Langone Health, National Heart, Lung, and Blood Institute (NHLBI)
SARS-CoV2 Infection
04/25
05/25
NCT01606826: Severe Asthma Research Program

Active, not recruiting
N/A
1100
US
Milton S. Hershey Medical Center, National Heart, Lung, and Blood Institute (NHLBI)
Asthma
06/26
12/26
Perlmutter, Joel
vUHDRS, NCT05748288: Development of the Virtual Unified Huntington's Disease Rating Scale

Completed
N/A
60
US
Huntington Study Group
Huntington Disease
05/23
05/23
NCT06084533: CS1P1 PET Studies of Neuroinflammation in Parkinson Disease

Enrolling by invitation
N/A
80
US
[11C]-CS1P1
Washington University School of Medicine
Parkinson Disease
02/29
02/29
NCT02763683: Investigations of Dementia in Parkinson Disease

Recruiting
N/A
320
US
PiB and VAT
Washington University School of Medicine, National Institutes of Health (NIH), National Institute of Neurological Disorders and Stroke (NINDS), National Institute on Aging (NIA)
Parkinsons
03/30
03/30
NCT01052350: PET Imaging in Parkinson Disease Dementia

Active, not recruiting
N/A
320
US
Washington University School of Medicine
Parkinson's Disease
07/30
07/30
NCT01574053: Enroll -HD: A Prospective Registry Study in a Global Huntington's Disease Cohort

Recruiting
N/A
35000
Europe, Canada, US, RoW
CHDI Foundation, Inc.
Huntington's Disease
01/62
01/62
Avidan, Michael S
TECTONICS, NCT03923699: Telemedicine Control Tower for the Operating Room: Navigating Information, Care and Safety

Completed
3
79560
US
Anesthesia Control Tower monitoring
Washington University School of Medicine, National Institute of Nursing Research (NINR)
Surgery, Surgery--Complications, Perioperative/Postoperative Complications
01/23
01/23
THRIVE, NCT05346588: Feasibility Trial

Completed
3
300
US
Anesthetic technique Propofol TIVA, Propofol TIVA, Anesthetic technique inhaled agent, Inhaled agent
Washington University School of Medicine, University of Michigan, University of Pennsylvania, Stanford University, Patient-Centered Outcomes Research Institute
Surgery--Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia Emergence Delirium, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Nausea, Postoperative, Anesthesia Morbidity, Depression, Sleep Disorders, Circadian Rhythm
04/23
06/23
ENGAGES, NCT02692300: EEG Guidance of Anesthesia (-CANADA)

Completed
N/A
1225
Canada
EEG-Guided Group
University of Manitoba, Queen's University, University of Washington, University of Toronto, Université de Montréal
Post-operative Delirium
02/22
02/23
RCT Pilot, NCT06732921: Recovery Control Tower Feasibility Pilot

Recruiting
N/A
8500
US
Alertwatch - Recovery Control Tower
Washington University School of Medicine
Elective Surgery
12/24
09/25
NCT04877535: Pilot Study for Postoperative Machine Learning

Recruiting
N/A
360
US
ML-based report card
Washington University School of Medicine, National Center for Advancing Translational Sciences (NCATS)
Surgery--Complications
03/24
07/24
NCT05575128: Behavioral Activation and Medication Optimization In Older Adults Undergoing Cardiac Procedures

Recruiting
N/A
100
US
Behavioral activation, Medication optimzation, Care as usual
Washington University School of Medicine, National Institute of Mental Health (NIMH)
Cardiac Surgery, Older Adults, Depression, Anxiety
11/24
03/25
NCT05685511: Behavioral Activation and Medication Optimization For Improving Perioperative Mental Health In Older Adults Undergoing Oncologic Surgery

Recruiting
N/A
110
US
Behavioral Activation, Medication Optimization
Washington University School of Medicine, National Institute of Mental Health (NIMH)
Older Adults, Anxiety, Depression, Major Surgical Resection of a Thoracic Malignancy, Major Surgical Resection of an Abdominal Malignancy
05/25
05/25
CPMH, NCT05697835: Perioperative Mental Health in Orthopedic Surgery

Recruiting
N/A
100
US
Behavioral activation, Medication optimzation, Care as usual
Washington University School of Medicine, National Institute of Mental Health (NIMH)
Orthopedic Surgery, Older Adults, Depression, Anxiety
02/26
02/26
THRIVE, NCT05991453: Trajectories of Recovery After Intravenous Propofol Versus Inhaled VolatilE Anesthesia Trial

Recruiting
N/A
12500
US
Anesthetic technique Propofol TIVA, Propofol TIVA, Anesthetic technique inhaled agent, Inhaled agent
Washington University School of Medicine, Patient-Centered Outcomes Research Institute, University of Michigan
Surgery-Complications, Anesthesia Complication, Anesthesia Awareness, Anesthesia, Surgery, Quality of Life, Pain, Postoperative, Anesthesia Morbidity
07/27
07/28
Wilfley, Denise E
iAIM EDU, NCT04162847: Harnessing Mobile Technology to Reduce Mental Health Disorders in College Populations

Completed
N/A
6256
US
SilverCloud Health Intervention
Washington University School of Medicine, National Institute of Mental Health (NIMH), Palo Alto University, University of Michigan, Penn State University
Anxiety Disorders, Depressive Disorder, Eating Disorders
12/23
12/23
NCT05499676: Helping HAND: Healing Anorexia Nervosa Digitally

Active, not recruiting
N/A
90
US
SilverCloud Health Mobile Intervention, Social Networking Intervention: Facebook
Washington University School of Medicine, National Institute of Mental Health (NIMH)
Anorexia Nervosa
03/25
03/25
NCT05410574: Family-Based Behavioral Treatment for Childhood Survivors of Acute Lymphoblastic Leukemia

Terminated
N/A
17
US
Family-based Behavioral Weight Loss Treatment, FBT
Washington University School of Medicine
Acute Lymphoblastic Leukemia
07/23
03/24
TEAM UP, NCT03843424: Treatment Efforts Addressing Child Weight Management by Unifying Patients, Parents & Providers

Completed
N/A
1460
US
eSOC program, FBT program
Washington University School of Medicine, Patient-Centered Outcomes Research Institute, Blue Cross and Blue Shield of Louisiana, American Academy of Pediatrics, Pennington Biomedical Research Center, Louisiana Healthcare Connections, Nationwide Children s Hospital in Columbus, Ohio, University of Rochester
Obesity, Childhood, Pediatric Obesity, Childhood Obesity, Adolescent Obesity, Overweight, Overweight and Obesity, Overweight or Obesity, Overweight Adolescents, Weight Gain, Overnutrition, Body Weight, Body Weight Changes, Nutrition Disorders
06/24
07/24
RYSE, NCT05212155: Family-based Behavioral Treatment for Childhood Obesity

Active, not recruiting
N/A
108
US
family-based behavioral treatment (FBT)
Washington University School of Medicine, Centers for Disease Control and Prevention, Children's Mercy Hospital Kansas City, Freeman Health System
Obesity, Childhood
10/24
12/24
FBT 2, NCT06728800: Leveraging Interactive Digital Technology to Increase Access to Family-Based Behavioral Treatment for Childhood Obesity

Not yet recruiting
N/A
140
US
FBT 2.0, Information-and-referral
3-C Institute for Social Development, Washington University School of Medicine, University at Buffalo
Childhood Obesity
06/26
06/26
Zoberi, Imran
SWIFT RT, NCT06559540: Ultra-Hypofractionated vs. Hypofractionated Radiation for Node-Positive Breast Cancer

Recruiting
2
220
US
Hypofractionated radiation, RT, Ultra-hypofractionated breast/chest wall and regional nodal radiation, SWIFT RT
Washington University School of Medicine
Node-positive Breast Cancer
04/34
04/34
NCT03921008: Induction Paclitaxel Followed by Concurrent Paclitaxel and Radiation Therapy for Cutaneous Angiosarcoma

Recruiting
1/2
19
US
Paclitaxel, Taxol, Radiation therapy, Research blood draw
Washington University School of Medicine
Cutaneous Angiosarcoma
08/28
08/28
NCT02076074: Single Fraction High-Gradient Partial Breast Irradiation in Treating Patients With Low-Risk Stage 0-I Breast Cancer

Completed
N/A
50
US
accelerated partial breast irradiation, APBI
Washington University School of Medicine
Breast Neoplasms
05/23
05/23
NCT04354064: Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Recruiting
N/A
100
US
Washington University School of Medicine, Roche Sequencing Solutions, The Foundation for Barnes-Jewish Hospital, National Center for Advancing Translational Sciences (NCATS), Radiological Society of North America, Skandalaris, The V Foundation for Cancer Research, National Institute of General Medical Sciences (NIGMS)
Healthy Volunteer, Prostate Cancer, Head and Neck Cancer, Esophageal Cancer, Genitourinary Cancer, Sarcoma, Breast Cancer, Colon Cancer, Gastrointestinal Cancer, Solid Tumor Cancer, Lung Cancer, Skin Cancer, Melanoma
12/25
12/25
NCT03612648: Three Fraction Accelerated Partial Breast Irradiation as the Sole Method of Radiation Therapy for Low-risk Stage 0 and I Breast Carcinoma

Active, not recruiting
N/A
77
US
Three Fraction Accelerated Partial Breast Irradiation, TRI-APBI, Partial mastectomy
Washington University School of Medicine
Breast Carcinoma, Breast Cancer
03/26
03/26
BreaStBRT, NCT04849871: Single Fraction Accelerated Partial Breast Irradiation vs. Five Fraction Accelerated Partial Breast Irradiation for Low-risk Stage 0 and I Breast Carcinoma

Active, not recruiting
N/A
134
US
External Beam Accelerated Partial Breast Irradiation, APBI
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital
Breast Carcinoma, Breast Cancer, Stage 0 Breast Cancer, Stage I Breast Cancer
07/29
07/29
COOL-IT, NCT05505643: Cryoablation vs Lumpectomy in T1 Breast Cancers

Recruiting
N/A
256
US
Endocare SlimLine Cryoprobe, Lumpectomy
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital, Varian Medical Systems
Breast Cancer, Breast Neoplasm
04/34
04/34
Semenkovich, Clay F
COMP-SR, NCT02122666: Composition & Function of Sarcoplasmic Reticulum in Persons With the Metabolic Syndrome

Completed
N/A
27
US
muscle biopsy
Washington University School of Medicine
Metabolic Syndrome
02/24
02/24
Peterson, Linda
iNIX-HF, NCT05562167: The Inorganic Nitrate and eXercise Performance in Heart Failure

Recruiting
2
75
US
KNO3, Potassium nitrate, Placebo
Washington University School of Medicine
Heart Failure
01/28
01/28
NCT02797184: Inorganic NItrate and EXercise Performance in Heart Failure (iNIX-HF): Dose Response

Active, not recruiting
1/2
42
US
KNO3, potassium nitrate, saltpeter
Washington University School of Medicine
Heart Failure
10/21
12/25
NCT01682356: Dietary Nitrate for Heart Failure

Completed
1/2
17
US
Beetroot juice, Beet It
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital
Heart Failure, Hypertension, Pulmonary
07/23
07/23
NCT05521984: Targeting Pediatric Brain Tumors and Relapsed/Refractory Solid Tumors With Sodium Glucose Cotransporter 2 Inhibitors (SGLT2i)

Recruiting
1
20
US
Dapagliflozin, Carmustine, Topotecan, Cyclophosphamide
Washington University School of Medicine, Children's Discovery Institute
Pediatric Brain Tumor, Pediatric Solid Tumor
08/26
11/26
NCT04887935: Neoadjuvant SGLT2 Inhibition in High-Risk Localized Prostate Cancer

Recruiting
1
24
US
Dapagliflozin, Farxiga
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital
Prostate Cancer, Cancer of Prostate
08/26
08/26
DRTC, NCT01067209: Reversal of Obese/Diabetic Cardiomyopathy After Gastric Bypass Surgery

Completed
N/A
18
US
Washington University School of Medicine
Cardiomyopathy
02/13
02/13
NCT02987049: Intensive Cardiac Rehabilitation (ICR): Tolerability and Effectiveness

Enrolling by invitation
N/A
500
NA
Washington University School of Medicine
Cardiac Disease
12/24
12/24
NCT04072393: Cardiac Rehabilitation for Patients Receiving Radiation Therapy for Thoracic Cancers

Terminated
N/A
24
US
Home-based cardiac rehabilitation
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital
Lung Cancer, Esophageal Cancer, Thoracic Cancer, Hodgkin Lymphoma, Hodgkin Disease, Non-hodgkin Lymphoma, Sarcoma, Thymoma, Breast Cancer
05/24
05/24
NCT00776035: Sex and Obesity: Effects on Heart Failure Study

Completed
N/A
19
US
PET (Positron Emission Tomography), PET scan, Echocardiogram, Echo, ^15O-water, 1-^11C-palmitate, 1-^11C-glucose
Washington University School of Medicine, The Foundation for Barnes-Jewish Hospital
Obesity, Heart Failure
04/11
04/11
NCT01372397: Reversal of Obesity Cardiomyopathy

Completed
N/A
27
US
Washington University School of Medicine
Cardiomyopathy
04/12
04/12
NCT06404047: RECOVER-ENERGIZE Platform Protocol

Recruiting
N/A
660
US
Personalized Cardiopulmonary Rehabilitation, Structured Pacing, Education, Usual Care
Duke University, National Heart, Lung, and Blood Institute (NHLBI)
Long COVID, Long Covid19, Long Covid-19
10/25
01/26
Tine, Brian Van
NCT06422806: Measuring if Immunotherapy Plus Chemotherapy is Better Than Chemotherapy Alone for Patients With Aggressive Poorly Differentiated Sarcomas

Recruiting
3
180
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Diagnostic Imaging, Medical Imaging, Doxorubicin, Adriablastin, Hydroxydaunomycin, Hydroxyl Daunorubicin, Hydroxyldaunorubicin, Echocardiography, EC, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNV Scan, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Pembrolizumab, BCD-201, GME 751, GME751, Keytruda, Lambrolizumab, MK 3475, MK-3475, MK3475, Pembrolizumab Biosimilar BCD-201, Pembrolizumab Biosimilar GME751, Pembrolizumab Biosimilar QL2107, Pembrolizumab Biosimilar RPH-075, QL2107, RPH 075, RPH-075, RPH075, SCH 900475, SCH-900475, SCH900475
National Cancer Institute (NCI)
Metastatic Undifferentiated Pleomorphic Sarcoma, Stage III Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Stage IV Soft Tissue Sarcoma of the Trunk and Extremities AJCC v8, Unresectable Undifferentiated Pleomorphic Sarcoma
06/26
06/26
ARGSARC, NCT05712694: Study of ADI-PEG 20 or Placebo Plus Gem and Doc in Previously Treated Subjects with Leiomyosarcoma

Recruiting
3
300
Canada, US, RoW
ADI PEG20, Pegargiminase, Placebo
Polaris Group
Soft Tissue Sarcoma
12/27
12/27
SUNRISELMS, NCT05269355 / 2022-000073-12: A Study of Unesbulin in Participants With Advanced Leiomyosarcoma (LMS)

Active, not recruiting
2/3
360
Europe, Canada, US, RoW
Unesbulin, PTC596, Dacarbazine, DTIC, Placebo
PTC Therapeutics, PTC Therapeutics, Inc.
Leiomyosarcoma
06/24
06/24
RINGSIDE, NCT04871282 / 2020-005833-34: A Study of AL102 in Patients With Progressing Desmoid Tumors

Active, not recruiting
2/3
192
Europe, US, RoW
AL102, Placebo
Immunome, Inc.
Desmoid, Desmoid Tumor
10/25
10/26
NCT05432791: Testing Olaparib and Temozolomide Versus the Usual Treatment for Uterine Leiomyosarcoma After Chemotherapy Has Stopped Working

Active, not recruiting
2/3
190
US
Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Scan, Bone Scintigraphy, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Multigated Acquisition Scan, Blood Pool Scan, Equilibrium Radionuclide Angiography, Gated Blood Pool Imaging, Gated Heart Pool Scan, MUGA, MUGA Scan, Multi-Gated Acquisition Scan, Radionuclide Ventriculogram Scan, Radionuclide Ventriculography, RNV Scan, RNVG, SYMA Scanning, Synchronized Multigated Acquisition Scanning, Olaparib, AZD 2281, AZD-2281, AZD2281, KU 0059436, KU-0059436, KU0059436, Lynparza, Olanib, Olaparix, PARP Inhibitor AZD2281, Pazopanib, GW786034, Temozolomide, CCRG-81045, Gliotem, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temizole, Temodal, Temodar, Temomedac, TMZ, Trabectedin, Ecteinascidin, Ecteinascidin 743, ET 743, ET-743, ET743, Yondelis, Transthoracic Echocardiography, TTE
National Cancer Institute (NCI)
Locally Advanced Uterine Corpus Leiomyosarcoma, Metastatic Uterine Corpus Leiomyosarcoma, Stage III Uterine Corpus Leiomyosarcoma AJCC v8, Stage IV Uterine Corpus Leiomyosarcoma AJCC v8, Unresectable Uterine Corpus Leiomyosarcoma
03/30
03/30
NCT03233698: Atezolizumab in Treating Patients With Newly Diagnosed and Metastatic Alveolar Soft Part Sarcoma That Cannot Be Removed by Surgery

Recruiting
2
26
US
Atezolizumab, Laboratory Biomarker Analysis, Pharmacological Study
National Cancer Institute (NCI)
Metastatic Alveolar Soft Part Sarcoma
12/18
12/18
NCI protocol 10250, NCT03880019: A Phase II Clinical Trial Evaluating the Combination of Olaparib and Temozolomide for the Treatment of Advanced Uterine Leiomyosarcoma

Active, not recruiting
2
23
US
Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Core Biopsy, BIOPSY, CORE, CNB, Core Needle, Core Needle Biopsy, Needle Biopsy, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Olaparib, AZD 2281, AZD-2281, AZD2281, KU 0059436, KU-0059436, KU0059436, Lynparza, Olanib, Olaparix, PARP Inhibitor AZD2281, Temozolomide, CCRG-81045, Gliotem, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temizole, Temodal, Temodar, Temomedac, TMZ
National Cancer Institute (NCI)
Stage III Uterine Corpus Leiomyosarcoma AJCC v8, Stage IV Uterine Corpus Leiomyosarcoma AJCC v8, Uterine Corpus Leiomyosarcoma
08/20
09/25
SPEARHEAD-1, NCT04044768 / 2019-000589-39: Spearhead 1 Study in Subjects With Advanced Synovial Sarcoma or Myxoid/Round Cell Liposarcoma

Oct 2022 - Jun 2023: BLA submission for treatment of synovial sarcoma
Checkmark Data from cohort 1 of SPEARHEAD-1 trial for synovial sarcoma or myxoid round cell liposarcoma
Nov 2022 - Nov 2022: Data from cohort 1 of SPEARHEAD-1 trial for synovial sarcoma or myxoid round cell liposarcoma
Checkmark Pooled analysis data from trials for sarcoma at AACR 2022
Jun 2022 - Jun 2022: Pooled analysis data from trials for sarcoma at AACR 2022
More
Active, not recruiting
2
52
Europe, Canada, US
afamitresgene autoleucel (previously ADP-A2M4)
Adaptimmune, Adaptimmune LLC
Synovial Sarcoma, Myxoid Liposarcoma
08/21
04/38
NCT02584309: Doxorubicin With Upfront Dexrazoxane for the Treatment of Advanced or Metastatic Soft Tissue Sarcoma

Completed
2
73
US
Dexrazoxane, Zinecard®, Totect®, Doxorubicin, Adriamycin, Hydroxydaunomycin Hydrochloride, Hydroxydoxorubicin Hydrochloride, Rubex
Washington University School of Medicine
Sarcoma, Soft Tissue, Soft Tissue Sarcoma, Undifferentiated Pleomorphic Sarcoma, Leiomyosarcoma, Liposarcoma, Synovial Sarcoma, Myxofibrosarcoma, Angiosarcoma, Fibrosarcoma, Malignant Peripheral Nerve Sheath Tumor, Epithelioid Sarcoma
07/22
07/22
NCT04200443: Cabozantinib and Temozolomide for the Treatment of Unresectable or Metastatic Leiomyosarcoma or Other Soft Tissue Sarcoma

Active, not recruiting
2
72
US
Cabozantinib, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Temozolomide, CCRG-81045, Imidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide, 3, 4-dihydro-3-methyl-4-oxo-, M & B 39831, M and B 39831, Methazolastone, RP-46161, SCH 52365, Temcad, Temodal, Temodar, Temomedac, TMZ
City of Hope Medical Center, National Cancer Institute (NCI)
Metastatic Leiomyosarcoma, Metastatic Soft Tissue Sarcoma, Stage III Uterine Corpus Leiomyosarcoma AJCC v8, Stage IIIA Uterine Corpus Leiomyosarcoma AJCC v8, Stage IIIB Uterine Corpus Leiomyosarcoma AJCC v8, Stage IIIC Uterine Corpus Leiomyosarcoma AJCC v8, Stage IV Uterine Corpus Leiomyosarcoma AJCC v8, Stage IVA Uterine Corpus Leiomyosarcoma AJCC v8, Stage IVB Uterine Corpus Leiomyosarcoma AJCC v8, Unresectable Leiomyosarcoma, Unresectable Soft Tissue Sarcoma
04/25
04/25
SURPASS-2, NCT04752358 / 2020-005802-24: ADP-A2M4CD8 in HLA-A2+ Subjects With MAGE-A4 Positive Esophageal or Esophagogastric Junction Cancers

Terminated
2
3
Europe, Canada, US
Autologous genetically modified ADP-A2M4CD8 cells
Adaptimmune, ICON plc
Esophageal Cancer, Esophagogastric Junction Cancer
06/23
12/23
NCT04595747: Testing the Anti-cancer Drug, Rogaratinib (BAY 1163877), for Treatment of Advanced Sarcoma With Alteration in Fibroblast Growth Factor Receptor (FGFR 1-4), and in Patients With SDH-deficient Gastrointestinal Stromal Tumor (GIST)

Active, not recruiting
2
48
US
Biopsy, BIOPSY_TYPE, Bx, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Rogaratinib, BAY-1163877, BAY1163877
National Cancer Institute (NCI)
Locally Advanced Gastrointestinal Stromal Tumor, Locally Advanced Sarcoma, Metastatic Gastrointestinal Stromal Tumor, Metastatic Sarcoma, Stage III Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8, Stage III Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal Gastrointestinal Stromal Tumor AJCC v8, Stage IV Gastric and Omental Gastrointestinal Stromal Tumor AJCC v8, Stage IV Small Intestinal, Esophageal, Colorectal, Mesenteric, and Peritoneal Gastrointestinal Stromal Tumor AJCC v8
01/25
01/25
ChonDRAgon, NCT04950075: Study of INBRX-109 in Conventional Chondrosarcoma

Recruiting
2
201
Europe, US, RoW
INBRX-109, Placebo
Inhibrx Biosciences, Inc
Conventional Chondrosarcoma
09/25
12/26
NCT04551430: Cabozantinib Combined With PD-1 and CTLA-4 Inhibition in Metastatic Soft Tissue Sarcoma

Active, not recruiting
2
105
US
Cabozantinib, Nivolumab, Opdivo, Ipilimumab, Yervoy
Washington University School of Medicine, Exelixis, Bristol-Myers Squibb
Metastatic Soft-tissue Sarcoma
06/24
06/30
NCT04040205: Abemaciclib for Bone and Soft Tissue Sarcoma With Cyclin-Dependent Kinase (CDK) Pathway Alteration

Recruiting
2
44
US
Abemaciclib, Verzenio
Medical College of Wisconsin
Chondrosarcoma, Osteosarcoma, Soft Tissue Sarcoma
06/25
06/26
PRECISION 1, NCT05103358: Phase 2 Basket Trial of Nab-sirolimus in Patients With Malignant Solid Tumors With Pathogenic Alterations in TSC1/TSC2 Genes

Active, not recruiting
2
120
US, RoW
nab-sirolimus, ABI-009
Aadi Bioscience, Inc.
Tumor, Tumor, Solid, Metastasis, Metastatic Cancer, Cancer, Cancer Metastatic, Tumors, Neoplasms, Neoplasm Metastasis, Solid Tumor, Advanced Solid Tumor, Advanced Cancer, Malignant Solid Tumor, Malignant Solid Neoplasm, Malignant Neoplasm, Malignant Tumor, TSC, TSC1, TSC2, Metastatic Solid Tumor, Metastatic Neoplasm
12/24
12/25
ZIABC011078, NCT03141684: Testing Atezolizumab Alone or Atezolizumab Plus Bevacizumab in People With Advanced Alveolar Soft Part Sarcoma

Hourglass Oct 2024 - Dec 2024 : Regulatory approval for alveolar soft part sarcoma
Active, not recruiting
2
63
US
Atezolizumab, MPDL 3280A, MPDL 328OA, MPDL-3280A, MPDL3280A, MPDL328OA, RG 7446, RG-7446, RG7446, RO 5541267, RO-5541267, RO5541267, Tecentriq, Bevacizumab, ABP 215, ABP-215, ABP215, Alymsys, Anti-VEGF, Anti-VEGF Humanized Monoclonal Antibody, Anti-VEGF Monoclonal Antibody SIBP04, Anti-VEGF rhuMAb, Avastin, Avzivi, Aybintio, BAT 1706, BAT-1706, BAT1706, BAT1706 Biosimilar, Bevacizumab awwb, Bevacizumab Biosimilar ABP 215, Bevacizumab Biosimilar BAT1706, Bevacizumab Biosimilar BEVZ92, Bevacizumab Biosimilar BI 695502, Bevacizumab Biosimilar CBT 124, Bevacizumab Biosimilar CT-P16, Bevacizumab Biosimilar FKB238, Bevacizumab Biosimilar GB-222, Bevacizumab Biosimilar HD204, Bevacizumab Biosimilar HLX04, Bevacizumab Biosimilar IBI305, Bevacizumab Biosimilar LY01008, Bevacizumab Biosimilar MB02, Bevacizumab Biosimilar MIL60, Bevacizumab Biosimilar Mvasi, Bevacizumab Biosimilar MYL-1402O, Bevacizumab Biosimilar QL 1101, Bevacizumab Biosimilar QL1101, Bevacizumab Biosimilar RPH-001, Bevacizumab Biosimilar SCT501, Bevacizumab Biosimilar Zirabev, Bevacizumab-adcd, Bevacizumab-awwb, Bevacizumab-aybi, Bevacizumab-bvzr, Bevacizumab-equi, Bevacizumab-maly, Bevacizumab-onbe, Bevacizumab-tnjn, BP102, BP102 Biosimilar, CT P16, CT-P16, CTP16, Equidacent, FKB 238, FKB-238, FKB238, HD204, Immunoglobulin G1 (Human-Mouse Monoclonal rhuMab-VEGF Gamma-Chain Anti-Human Vascular Endothelial Growth Factor), Disulfide With Human-Mouse Monoclonal rhuMab-VEGF Light Chain, Dimer, MB 02, MB-02, MB02, Mvasi, MYL-1402O, Onbevzi, Oyavas, PF 06439535, PF-06439535, PF06439535, QL1101, Recombinant Humanized Anti-VEGF Monoclonal Antibody, rhuMab-VEGF, SCT501, SIBP 04, SIBP-04, SIBP04, Vegzelma, Zirabev, Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography
National Cancer Institute (NCI)
Metastatic Alveolar Soft Part Sarcoma, Unresectable Alveolar Soft Part Sarcoma
10/25
10/25
NCT05440786 / 2021-004734-11: CAMPFIRE: A Study of Abemaciclib (LY2835219) in Participants With Ewing's Sarcoma

Recruiting
2
45
Europe, Japan, US, RoW
Abemaciclib, LY2835219, Irinotecan, Temozolomide
Eli Lilly and Company
Sarcoma, Ewing, Neoplasm Metastasis
02/27
09/28
NCT02584647: PLX3397 Plus Sirolimus in Unresectable Sarcoma and Malignant Peripheral Nerve Sheath Tumors

Active, not recruiting
1/2
43
US
PLX3397, No other name, Sirolimus, Rapamune
Gulam Manji, Daiichi Sankyo
Sarcoma, Malignant Peripheral Nerve Sheath Tumors
07/23
06/24
Keynote MK-3475-B66, NCT03611868: A Study of APG-115 in as a Monotherapy or Combination With Pembrolizumab in Patients With Metastatic Melanomas or Advanced Solid Tumors

Recruiting
1/2
230
US, RoW
Phase 1b: APG-115+pembrolizumab, KEYTRUDA®
Ascentage Pharma Group Inc., Merck Sharp & Dohme LLC
Unresectable or Metastatic Melanoma or Advanced Solid Tumors, Melanoma, Uveal Melanoma, P53 Mutation, MDM2 Gene Mutation, Cutaneous Melanoma, Mucosal Melanoma, Malignant Peripheral Nerve Sheath Tumors (MPNST)
12/24
03/25
NCT04892017: A Phase 1/2 Study of DCC-3116 in Patients With RAS/MAPK Pathway Mutant Solid Tumors

Recruiting
1/2
144
US
DCC-3116, Trametinib, Binimetinib, Sotorasib
Deciphera Pharmaceuticals, LLC
Non-Small Cell Lung Cancer, Advanced Solid Tumor, Metastatic Solid Tumor
08/27
08/28
NCT04887298: Study of Liposomal Annamycin for the Treatment of Subjects with Soft-Tissue Sarcomas (STS) with Pulmonary Metastases

Completed
1/2
36
US
Liposomal Annamycin (L-Annamycin)
Moleculin Biotech, Inc.
Sarcoma,Soft Tissue, Pulmonary Metastasis
09/22
08/24
NCT06077877: A Study to Investigate the Safety, Tolerability, Pharmacokinetics (PK), and Preliminary Anticancer Activity of GSK4524101 Alone or With Niraparib in Participants With Solid Tumors

Recruiting
1/2
135
Canada, US
GSK4524101, Niraparib
GlaxoSmithKline
Neoplasms
12/27
11/29
NCT05588648: Study to Assess Safety and Efficacy of Vactosertib in Adolescents and Adults With Recurrent, Refractory or Progressive Osteosarcoma

Recruiting
1/2
48
US, RoW
Vactosertib, TEW-7197
MedPacto, Inc.
Osteosarcoma
07/25
11/25
NCT05813327: Neoadjuvant ADI-PEG 20 + Ifosfamide + Radiotherapy in Soft Tissue Sarcoma

Recruiting
1/2
35
US
ADI PEG20, PEGylated arginine deiminase, Ifosfamide, ifex, Radiotherapy, Mesna, sodium 2-mercaptoethane sulfonate
Washington University School of Medicine, Polaris Group
Soft Tissue Sarcoma, Sts, Sarcoma,Soft Tissue
01/26
01/28
NCT03921008: Induction Paclitaxel Followed by Concurrent Paclitaxel and Radiation Therapy for Cutaneous Angiosarcoma

Recruiting
1/2
19
US
Paclitaxel, Taxol, Radiation therapy, Research blood draw
Washington University School of Medicine
Cutaneous Angiosarcoma
08/28
08/28
CFT1946-1101, NCT05668585: A Study to Characterize the Safety, Tolerability, and Preliminary Efficacy of CFT1946 as Monotherapy and Combination Therapy in Subjects With BRAF V600 Mutant Solid Tumors

Recruiting
1/2
206
Europe, US
CFT1946, Trametinib, Cetuximab
C4 Therapeutics, Inc.
Solid Tumors, Melanoma, NSCLC, CRC, ATC
03/27
04/27
NCT05616624: ADI-PEG 20 in Combination With Gemcitabine and Docetaxel After Progression on Frontline Therapy in Non-small Cell and Small Cell Lung Cancers

Recruiting
1/2
114
US
ADI-PEG 20, PEGylated arginine deiminase, Gemcitabine, Gemzar, Docetaxel, Taxotere
Washington University School of Medicine, Polaris Group
Non Small Cell Lung Cancer, Non-small Cell Lung Cancer, Small-cell Lung Cancer, Small Cell Lung Carcinoma
12/27
12/32
TRIDENT-1, NCT03093116 / 2016-003616-13: A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements

Hourglass Jan 2025 - Jan 2025 : Approval in EU for adv ROS1+ve NSCLC, adv NTRK+ve solid tumors
Hourglass Jan 2023 - Dec 2023 : Data readout from P1/2 TRIDENT-1 trial for ROS1 NSCLC and NTRK+ solid tumors
Jan 2023 - Dec 2023: Approval in US for 2L NSCLC
Hourglass Jul 2023 - Dec 2023 : Approval for ROS1+ NSCLC
Checkmark Top line data across ROS1-positive TKI-naïve and TKI-pretreated NSCLC cohorts in TRIDENT-1 trial
More
Recruiting
1/2
500
Europe, Canada, Japan, US, RoW
Oral repotrectinib (TPX-0005), repotrectinib
Turning Point Therapeutics, Inc., Zai Lab (Shanghai) Co., Ltd.
Locally Advanced Solid Tumors, Metastatic Solid Tumors
02/28
02/28
SALA-002-EW16, NCT03600649: Clinical Trial of SP-2577 (Seclidemstat) in Patients With Relapsed or Refractory Ewing or Ewing-related Sarcomas

Active, not recruiting
1
50
US
Seclidemstat, LSD1 Inhibitor, SP-2577, Cyclophosphamide, Topotecan
Salarius Pharmaceuticals, LLC, National Pediatric Cancer Foundation
Ewing Sarcoma, Myxoid Liposarcoma, Sarcoma,Soft Tissue, Desmoplastic Small Round Cell Tumor, Extraskeletal Myxoid Chondrosarcoma, Angiomatoid Fibrous Histiocytoma, Clear Cell Sarcoma, Primary Pulmonary Myxoid Sarcoma, Myoepithelial Tumor, Sclerosing Epithelioid Fibrosarcoma, Fibromyxoid Tumor
09/25
12/25
SURPASS, NCT04044859: ADP-A2M4CD8 as Monotherapy or in Combination With Either Nivolumab or Pembrolizumab in HLA-A2+ Subjects With MAGE-A4 Positive Tumors

Checkmark Results from SURPASS trial for MAGE-4 positive tumors
Sep 2022 - Sep 2022: Results from SURPASS trial for MAGE-4 positive tumors
Checkmark Clinical response data from SURPASS trial for solid tumors at CTOS 2019
Nov 2019 - Nov 2019: Clinical response data from SURPASS trial for solid tumors at CTOS 2019
Recruiting
1
120
Europe, Canada, US
Autologous genetically modified ADP-A2M4CD8 cells alone or in combination with nivolumab every four weeks or pembrolizumab every 6 weeks
Adaptimmune, ICON plc
Endometrial Cancer, Esophageal Cancer, Esophagogastric Junction (EGJ), Gastric (Stomach) Cancer, Head and Neck Cancer, Melanoma, Ovarian Cancer, Non-small Cell Lung (NSCLC), Urothelial Cancer
12/25
04/37
NCT03761095: A Study of Unesbulin (PTC596) in Combination With Dacarbazine in Participants With Advanced Leiomyosarcoma (LMS)

Completed
1
41
US
Unesbulin, PTC596, Dacarbazine, DTIC
PTC Therapeutics
Leiomyosarcoma
02/24
02/24
CFT8634-1101, NCT05355753: A Study to Assess the Safety and Tolerability of CFT8634 in Locally Advanced or Metastatic SMARCB1-Perturbed Cancers, Including Synovial Sarcoma and SMARCB1-Null Tumors

Terminated
1
49
US
CFT8634
C4 Therapeutics, Inc.
Synovial Sarcoma, Soft Tissue Sarcoma
12/23
12/23
INDP-D101, NCT05651022: DECOY20 Study in Patients with Advanced Solid Tumors

Recruiting
1
120
US
Decoy20
Indaptus Therapeutics, Inc, Translational Drug Development
Solid Tumor, Adult
06/27
09/27
MT-6402-001, NCT04795713: Study of MT-6402 in Subjects With Advanced Solid Cancer That Expresses PD-L1

Terminated
1
64
US
MT-6402
Molecular Templates, Inc.
Advanced Solid Tumor, Non-small Cell Lung Cancer, Squamous Cell Carcinoma of Head and Neck
10/24
10/24
NCT03391778 / 2018-004888-31: Adoptive Cell Therapy Long-term Follow-up (LTFU) Study

Recruiting
1
250
Europe, Canada, US, RoW
ADP adoptive cell therapy
Adaptimmune
Neoplasms
04/32
04/32
NCT04354064: Circulating Tumor DNA (ctDNA) for Early Treatment Response Assessment of Solid Tumors

Recruiting
N/A
100
US
Washington University School of Medicine, Roche Sequencing Solutions, The Foundation for Barnes-Jewish Hospital, National Center for Advancing Translational Sciences (NCATS), Radiological Society of North America, Skandalaris, The V Foundation for Cancer Research, National Institute of General Medical Sciences (NIGMS)
Healthy Volunteer, Prostate Cancer, Head and Neck Cancer, Esophageal Cancer, Genitourinary Cancer, Sarcoma, Breast Cancer, Colon Cancer, Gastrointestinal Cancer, Solid Tumor Cancer, Lung Cancer, Skin Cancer, Melanoma
12/25
12/25
NCT03141021: Multi-Institutional Registry for Malignant Peripheral Nerve Sheath Tumors

Recruiting
N/A
1050
Europe, Canada, Japan, US, RoW
Washington University School of Medicine, Boston's Children Hospital
Malignant Peripheral Nerve Sheath Tumors
04/53
04/53
Bateman, Randall
DIAN-TU, NCT06384573: Amyloid Removal Trial (ART) in Dominantly Inherited Alzheimer's Disease

Recruiting
3
65
Europe, US, RoW
lecanemab, BAN2401
Washington University School of Medicine, Alzheimer's Association, Eisai Inc.
Alzheimer's Disease, Dementia, Alzheimer's Disease, Familial
11/29
11/29
DIAN-TU, NCT06424236: Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia: A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation

Terminated
2/3
73
Europe, US, RoW
Gantenerumab, RO4909832
Washington University School of Medicine, Hoffmann-La Roche, Alzheimer's Association, National Institute on Aging (NIA)
Alzheimers Disease, Dementia, Alzheimers Disease, Familial
10/23
11/23
DIAN-TU, NCT05269394: Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation

Active, not recruiting
2/3
197
Europe, Canada, Japan, US, RoW
E2814, Lecanemab, BAN2401, Matching Placebo (E2814)
Washington University School of Medicine, Alzheimer's Association, National Institute on Aging (NIA), Accelerating Medicines Partnership (AMP), Eisai Inc.
Alzheimers Disease, Dementia, Alzheimers Disease, Familial
04/28
07/28
DIAN-TU, NCT01760005 / 2013-000307-17: Dominantly Inherited Alzheimer Network Trial: An Opportunity to Prevent Dementia. A Study of Potential Disease Modifying Treatments in Individuals at Risk for or With a Type of Early Onset Alzheimer's Disease Caused by a Genetic Mutation. Master Protocol -001

Checkmark From DIAN-TU trial
Feb 2020 - Feb 2020: From DIAN-TU trial
Checkmark Top-line data from DIAN-TU trial in rare inherited form of Alzheimer's disease
Feb 2020 - Feb 2020: Top-line data from DIAN-TU trial in rare inherited form of Alzheimer's disease
Checkmark DIAN TU: N=210
More
Recruiting
2/3
490
Europe, Canada, Japan, US, RoW
Gantenerumab, RO4909832, Solanezumab, LY2062430, Matching Placebo (Gantenerumab), Matching Placebo (Solanezumab), E2814, Lecanemab, BAN2401, Matching Placebo (E2814)
Washington University School of Medicine, Eli Lilly and Company, Hoffmann-La Roche, Alzheimer's Association, National Institute on Aging (NIA), Avid Radiopharmaceuticals, Accelerating Medicines Partnership (AMP), Eisai Inc., Janssen, LP
Alzheimers Disease, Dementia, Alzheimers Disease, Familial
04/28
07/28
NCT03938870: CNS Tau Kinetics in Healthy Aging and Alzheimer's Disease

Completed
N/A
96
US
L-Leucine 13C6
Washington University School of Medicine, BrightFocus Foundation, National Institutes of Health (NIH)
Alzheimer's Disease, Brain Diseases, Central Nervous System Diseases, Delirium, Dementia, Amnestic, Cognitive Disorders, Dementia, Mental Disorders, Nervous System Diseases, Neurodegenerative Diseases, Tauopathies
07/23
07/23
SEABIRD, NCT03899844: Study to Evaluate Amyloid in Blood and Imaging Related to Dementia

Completed
N/A
1122
US
Blood collection, PiB PET/MRI, and cognitive testing
Washington University School of Medicine
Alzheimer Disease, Alzheimer Dementia
01/24
01/24
DIAN, NCT00869817: Dominantly Inherited Alzheimer Network

Recruiting
N/A
700
Europe, Canada, Japan, US, RoW
Washington University School of Medicine, National Institute on Aging (NIA)
Alzheimer's Disease
07/25
07/25
SUNBIRD, NCT06547099: Study to Understand Novel Biomarkers in Researching Dementia

Enrolling by invitation
N/A
1800
US
Clinical tau PET, Clinical amyloid test, Research blood collection, Cognitive assessments
Washington University School of Medicine, National Institute on Aging (NIA)
Alzheimer Disease, Mild Cognitive Impairment, Dementia
12/28
12/28
Kreuter, Matthew W
NCT03194958: Helping Poor Smokers Quit

Completed
N/A
1944
US
Specialized Quitline, Basic Needs Navigator
Washington University School of Medicine, National Institutes of Health (NIH), National Cancer Institute (NCI)
Smoking Cessation, Smoking, Tobacco, Smoking, Cigarette, Smoking, Pipe, Smoking (Tobacco) Addiction, Smoking, Tobacco Use, Tobacco Dependence, Tobacco Use Cessation, Tobacco Smoking, Tobacco; Use, Rehabilitation, Nicotine Dependence, Nicotine Use Disorder, Nicotine Dependence, Cigarettes, Nicotine Dependence Tobacco Product
07/22
07/22
NCT04311983: Interventions to Help More Low-income Smokers Quit

Completed
N/A
1973
US
Tobacco Quitline, Smoke Free Home
Washington University School of Medicine, National Cancer Institute (NCI)
Tobacco Use Cessation, Smoking Behaviors, Health Disparity
09/23
09/23
NCT04427839: Expanding Population-level Interventions to Help More Low-income Smokers Quit

Recruiting
N/A
1980
US
Tobacco Quitline, Smoke Free Homes
Washington University School of Medicine, National Cancer Institute (NCI)
Tobacco Use Cessation, Smoking Behaviors, Health Disparity
06/24
06/25
 

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