| Zhang, Wei |
NCT04504864: Low-dose Aspirin Therapy in Patients With Ischemic Stroke and Microbleeds |
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| Recruiting | 4 | 400 | RoW | low-dose aspirin, conventional-does aspirin | Xijing Hospital, Shaanxi Provincial People's Hospital, The First Affiliated Hospital of Jiaotong University, Tang-Du Hospital, The First Affiliated Hospital of Xi'an Medical University, Xi'an Central Hospital, Xiangyang Central Hospital, Baoji Central Hospital | Ischemic Stroke | 02/22 | 08/22 | | |
| Active, not recruiting | 4 | 130 | RoW | Dexamethasone lipid microsphere plus ropivacaine, ropivacaine plus D-PAL, Ropivacaine alone | Beijing Tiantan Hospital | Pain, Postoperative | 09/23 | 12/23 | | |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease |
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| Recruiting | 4 | 1312 | RoW | GV-971, Placebo | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer's Disease | 06/29 | 12/29 | | |
NCT04504396: Safety and Efficacy of PB-119 in Subjects With Type 2 Diabetes and Not Well-controlled by Metformin Monotherapy |
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| Completed | 3 | 620 | RoW | GLP-1 receptor agonist, Placebo, PB-119 Placebo | PegBio Co., Ltd. | Type 2 Diabetes Mellitus (T2DM) | 09/22 | 05/23 | | |
NCT04683406: A Study of ZSP1273 Tablets in Patients With Acute Uncomplicated Influenza A |
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| Completed | 3 | 750 | RoW | ZSP1273 600 mg, Placebo to Oseltamivir, Oseltamivir(oral), Placebo to ZSP1273 | Guangdong Raynovent Biotech Co., Ltd | Influenza A | 04/23 | 05/23 | | |
NCT06103825: A Twelve-week, Double-blind, Placebo-controlled, Randomized, Parallel-group, Multicenter Study to Evaluate the Efficacy and Safety of Solriamfetol in the Treatment of Excessive Daytime Sleepiness (EDS) in Patients With Obstructive Sleep Apnea (OSA) |
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| Recruiting | 3 | 204 | RoW | Solriamfetol, Placebo | Ignis Therapeutics (Suzhou) Limited | Excessive Daytime Sleepiness Associated With Obstructive Sleep Apnea | 09/24 | 10/24 | | |
| Recruiting | 3 | 1200 | Europe, Canada, Japan, US, RoW | Remternetug, LY3372993, Placebo | Eli Lilly and Company | Alzheimer's Disease | 04/29 | 10/30 | | |
| Recruiting | 3 | 1500 | Europe, RoW | Donanemab, (LY3002813), Placebo | Eli Lilly and Company | Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders | 04/27 | 04/27 | | |
NCT05215379: Neoadjuvant Chemoradiation Therapy Combined With Immunotherapy for MSS Ultra-low Rectal Cancer |
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| Recruiting | 2/3 | 180 | RoW | xintilimab injection, Control | Changhai Hospital | Neoadjuvant Chemoradiation Therapy, Rectal Cancer, Immunotherapy, Microsatellite Instability Low | 10/24 | 04/25 | | |
NCT05811442: Study of 50561 in Patients With Mild or Moderate Alzheimer's Disease |
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| Recruiting | 2a | 60 | RoW | 50561 high dose, 50561 low dose, Placebo | Beijing Joekai Biotechnology LLC | Alzheimer's Disease | 05/24 | 06/24 | | |
NCT03746223: Intravitreal Methotrexate and R2(Rituximab & Lenalidomide) Regimen in Newly-diagnosed Primary Vitreoretinal Lymphoma |
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| Recruiting | 2 | 42 | RoW | Methotrexate, Rituximab, Lenalidomide | Peking Union Medical College Hospital | Primary Intraocular Lymphoma | 11/20 | 10/25 | | |
NCT05229029: RSYR for Fatigue Reduction in Cancer Fatigue Caused by Chemotherapy |
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| Active, not recruiting | 2 | 196 | RoW | TCM Formula, RSYR decoction, Placebo, Placebo dicoction | Peking University Cancer Hospital & Institute | Cancer-related Problem/Condition | 09/23 | 06/24 | | |
NCT04899427: Phase II Study of Orelabrutinib Combined With PD-1 Inhibitor in Relapsed/Refractory Primary Central Nervous System Lymphoma |
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| Recruiting | 2 | 32 | RoW | orelabrutinib, Sintilimab, Tislelizumab | Peking Union Medical College Hospital, Beijing Hospital, Beijing Tongren Hospital, Beijing Luhe Hospital, Shanxi Province Renmin Hospital, Henan Cancer Hospital, Henan Province Renmin Hospital, The Second Affiliated Hospital of Dalian Medical University, The Forth Hospital of Hebei Medical University, The First Hospital of Chinese Medical University, Qilu Hospital of Shandong University, The First Hospital of Zhengzhou University | Primary Central Nervous System Lymphoma | 03/23 | 10/23 | | |
NCT06259526: A Study of the Effectiveness and Safety of JS1-1-01 in Patients With Moderate to Severe Depression |
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| Recruiting | 2 | 260 | RoW | Placebo group, JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 low-dose group, JS1-1-01 pills; JS1-1-01 placebo pills; Duloxetine hydrochloride placebo capsules, JS1-1-01 pills; JS1-1-01 placebo pills, JS1-1-01 high-dose group, JS1-1-01 pills; Duloxetine hydrochloride placebo capsules, Active drug group, JS1-1-01 placebo pills; Duloxetine hydrochloride enteric coated capsule | Tasly Pharmaceutical Group Co., Ltd | Depression | 04/25 | 04/25 | | |
NCT05179213: Azacytidine Plus Chidamide in the Treatment of Relapsed and Refractory Angioimmunoblastic T-cell Lymphoma |
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| Not yet recruiting | 2 | 20 | RoW | Azacitidine, Chidamide | Peking Union Medical College Hospital, Beijing Longfu Hospital | Angioimmunoblastic T-cell Lymphoma | 01/24 | 05/24 | | |
NCT06093841: Relmacabtagene Autoleucel as Second-Line Therapy in Adult Patients With Aggressive B-cell NHL |
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| Not yet recruiting | 2 | 46 | RoW | Relmacabtagene Autoleucel, JWCAR029, Fludarabine, Cyclophosphamide | Shanghai Ming Ju Biotechnology Co., Ltd. | Lymphoma, Large B-Cell, Diffuse, Follicular Lymphoma Grade 3B, High-grade B-cell Lymphoma, Mediastinal B-Cell Diffuse Large Cell Lymphoma | 08/24 | 02/27 | | |
NCT05555901: The Efficacy and Safety of Fruquintinib Plus Chemotherapy as Second-line Treatment in Metastatic Colorectal Cancer |
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| Recruiting | 2 | 116 | RoW | Fruquintinib+ chemotherapy, Bevacizumab+ chemotherapy | Fudan University | Metastatic Colorectal Cancer | 09/25 | 09/25 | | |
NCT02987244: Chidamide Plus CHOEP Combined With Upfront ASCT in Untreated Peripheral T-cell Lymphoma |
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| Recruiting | 1/2 | 100 | RoW | Chidamide, epidaza, Cyclophosphamide, Epirubicin, Vindesine, Etoposide, Prednisone | Peking Union Medical College Hospital, Chinese PLA General Hospital, Peking University First Hospital, Peking University Third Hospital, Peking University Cancer Hospital & Institute, Tianjin Medical University Cancer Institute and Hospital | T Cell Non-Hodgkin's Lymphoma | 03/20 | 03/23 | | |
GLORY, NCT04270591: Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer |
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| Recruiting | 1/2 | 183 | Japan, US, RoW | Glumetinib, SCC244 | Haihe Biopharma Co., Ltd. | C-Met Exon 14 Mutation | 10/23 | 12/23 | | |
NCT05464433: Tislelizumab Combined With Mitoxantrone Hydrochloride Liposome in Extranodal Natural Killer/T Cell Lymphoma |
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| Recruiting | 1/2 | 46 | RoW | Tislelizumab combined with Liposomal mitoxantrone hydrochloride, Maintenance of tislelizumab | Sun Yat-sen University | Extranodal Natural Killer T Cell Lymphoma | 01/24 | 01/25 | | |
| Recruiting | 1/2 | 120 | RoW | Chidamide, HDACi, Fludarabine and cyclophosphamide, FC regimen, Anti-CD19 CAR-T cells, Relma-cel, Axi-cel, Other commercial CAR-T cells, Experimental CAR-T cells | Chinese PLA General Hospital | Non Hodgkin's Lymphoma | 06/24 | 06/25 | | |
NCT06393413: To Explore the Therapeutic Potential of Jiedu Yizhi Formula for Alzheimer 's Disease |
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| Completed | 1 | 62 | RoW | Jiedu Yizhi Formula, Donepezil Hydrochloride Tablets | Changchun University of Chinese Medicine | Ensure the Legality and Compliance of the Testing Process | 12/23 | 04/24 | | |
NCT05240950: Anti-CEA CAR-T Cells to Treat Colorectal Liver Metastases |
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| Recruiting | 1 | 18 | RoW | Anti-CEA CAR-T Cells | Changhai Hospital | Colorectal Cancer, Metastatic Liver Cancer | 12/23 | 12/26 | | |
NCT05577091: Tris-CAR-T Cell Therapy for Recurrent Glioblastoma |
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| Recruiting | 1 | 10 | RoW | Inverse correlated dual-target, truncated IL7Ra modified CAR -expressing autologous T-lymphocytes., Autologous Tris-CAR-T cell. | Beijing Tiantan Hospital, Beijing Neurosurgical Institute, Tasly Pharmaceutical Group Co., Ltd | Recurrent Glioblastoma | 11/24 | 11/32 | | |
NCT06515938: Study on New Strategies for Hepatitis B Virus Immunization |
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| Completed | N/A | 1169 | RoW | 20μg Engerix-B hepatitis B vaccine, 20μg Kangtai hepatitis B vaccine, 60μg Kangtai hepatitis B vaccine, 20μg CHO | Wu Jiang | Vaccine Reaction | 06/14 | 12/15 | | |
NCT05159804: Association Between Carotid Plaque Length and Cardiovascular Events |
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| Active, not recruiting | N/A | 3637 | RoW | | Changhai Hospital, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine | Coronary Arteriosclerosis | 06/21 | 12/30 | | |
| Recruiting | N/A | 630 | Europe, US, RoW | ROX index algorithm | Hospital Universitari Vall d'Hebron Research Institute | Acute Hypoxemic Respiratory Failure | 12/24 | 06/25 | | |
NCT05843487: Association Between Carotid Plaque Length and Cardiovascular Outcomes |
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| Active, not recruiting | N/A | 3000 | RoW | | Changhai Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital | Coronary Artery Disease, Carotid Plaque | 03/22 | 12/30 | | |
NCT03958435: Real-world Retrospective Data Analysis of Adjuvant Therapy for Patients With Stage II-III Colon Cancer After Radical Surgery |
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| Recruiting | N/A | 20000 | RoW | | Second Affiliated Hospital, School of Medicine, Zhejiang University | Stage II Colon Cancer, Stage III Colon Cancer, Adjuvant Therapy | 10/22 | 12/23 | | |
| Recruiting | N/A | 10254 | RoW | | Limeng Chen | Chronic Kidney Diseases, Chronic Kidney Disease-Mineral and Bone Disorder | 12/24 | 12/24 | | |
NCT05485857: Influence of Arrangement of Small Intestine Order on the Recovery of Bowel Function After Laparoscopic Colorectal Surgery |
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| Completed | N/A | 160 | RoW | Arrangement of small intestine order before close the abdomen | Changhai Hospital | Postoperative Complications | 02/23 | 03/23 | | |
NCT05634473: A Study to Evaluate the Sensitivity and Specificity of Inhaled Methacholine in Bronchial Provocation Test |
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| Not yet recruiting | N/A | 280 | RoW | Methacholine Chloride | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Asthma | 02/23 | 06/23 | | |
NCT04853238: Chronic Obstructive Pulmonary Disease (COPD) Maintenance Treatment Patterns in China |
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| Completed | N/A | 1507 | RoW | Prospective observational cohort study | GlaxoSmithKline | Pulmonary Disease, Chronic Obstructive | 11/22 | 02/23 | | |
ZCFZZLXGBDFYHZ, NCT05692258: Acupuncture as an Adjunctive Therapy for Covid-19 Omicron Randomised Controlled Trial in Patients With Moderate/Severe Pneumonia |
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| Recruiting | N/A | 146 | RoW | Acupuncture, basic therapy | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Acupuncture, Covid-19 Omicron, Pulmonary Function | 04/23 | 04/23 | | |
NCT05752097: [18F]AlF-NOTA-FAPI-04 PET/CT in Inflammation and Fibrosis in Renal Diseases |
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| Recruiting | N/A | 30 | RoW | [18F]AlF-NOTA-FAPI-04 PET/CT examination, Renal puncture biopsy | Sichuan Provincial People's Hospital | 18F-FAPI PET/CT Examination, Renal Puncture Biopsy | 08/24 | 11/24 | | |
GJZLBQGNZA, NCT05749354: Clinical Efficacy of Acupuncture on the Liver Meridian in Men With Erectile Dysfunction Reserve |
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| Recruiting | N/A | 159 | RoW | electroacupuncture, acupuncture | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Erectile Dysfunction, Acupuncture Therapy, Median Nerve Disease | 12/23 | 12/23 | | |
PCOS, NCT04984070: Research on Risk Factors and Interventions of Polycystic Ovary Syndrome Complicated With Depression and Anxiety |
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| Recruiting | N/A | 100 | RoW | Oral Contraceptives, Combined, Danie-35, Drospirenone and Ethinylestradiol Tablets (I), Drospirenone and Ethinylestradiol Tablets (Ⅱ), Metformin Pill, Metformin, lifestyle intervention | Fudan University | PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries, Depression, Anxiety | 12/23 | 12/24 | | |
NCT05183425: Patient-derived Organoids Predicts the Clinical Efficiency of Colorectal Liver Metastasis |
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| Recruiting | N/A | 60 | RoW | | Changhai Hospital | Explore the Consistency of Drug Sensitivity Between Primary Colorectal Cancer and Liver Metastases | 12/23 | 12/24 | | |
| Recruiting | N/A | 198 | RoW | electropuncture, acupuncture | The First Affiliated Hospital of Hunan University of Traditional Chinese Medicine | Ovarian Reserve, Acupuncture Therapy, Meridian | 12/23 | 12/23 | | |
NCT05815069: [18F]AlF-NOTA-pentixather PET/CT in Patients With Suspected Primary Hyperaldosteronism |
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| Recruiting | N/A | 20 | RoW | [18F]AlF-NOTA-pentixather PET/CT, pathological examination | Sichuan Provincial People's Hospital | Aldosterone-Producing Adenoma | 01/24 | 06/24 | | |
| Recruiting | N/A | 20 | RoW | Glofitamab | Peking Union Medical College Hospital | DLBCL - Diffuse Large B Cell Lymphoma | 12/27 | 12/28 | | |
NCT06254716: A Study on the Prognosis of Two Different Surgery Methods in Patients With Rectal Endometriosis |
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| Recruiting | N/A | 90 | RoW | disc resection, segmental resection | Fudan University | Gastrointestinal Function, Quality of Life, Pregnancy Outcomes | 12/24 | 12/24 | | |
proOMCRC, NCT04716257: A Prospective, Multi-center, Real-world Study of Ovarian Metastatic Colorectal Cancer Patients |
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| Recruiting | N/A | 400 | RoW | | West China Hospital, Sun Yat-sen University, Cancer Hospital of China Medical University, Liaoning Cancer Hospital & Institute, Changhai Hospital, Naval Medical University | Ovarian Metastasis, Colorectal Cancer | 09/25 | 09/25 | | |
NCT06204497: The Safety and Efficiency of Stent-based Diverting Technique Versus Ileostomy in Rectal Cancer Patients |
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| Recruiting | N/A | 570 | RoW | Stent-based Diverting Technique | Sir Run Run Shaw Hospital | Rectal Neoplasms | 12/24 | 06/25 | | |
VERONICA, NCT05486923: Validity and Reliability Evaluation of the PRO-CTCAE for Adult-type Diffuse Gliomas Patients in Chinese Population |
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| Recruiting | N/A | 450 | RoW | | Huashan Hospital | Glioma, Patient Reported Outcome Measures, Self Report, Adverse Effects | 04/25 | 12/25 | | |
NCT05882552: Tilted Gaze Target Test in the Examination of Children With Superior Oblique Muscle Palsy |
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| Not yet recruiting | N/A | 80 | NA | Tilted Gaze Target Tast, Conventional Examination Methods | Tianjin Eye Hospital | Children With Torticollis | 06/24 | 12/24 | | |
NCT06510127: An AI Model Predicts the Efficacy of Neoadjuvant Chemotherapy for Breast Cancer: a Multicenter, Bidirectional Cohort Study |
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| Enrolling by invitation | N/A | 840 | RoW | | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Jinan University | Breast Cancer | 06/25 | 01/26 | | |
NCT03651986: Diagnostic and Monitoring Significance of ctDNA Methylation Analysis by NGS in Benign and Malignant Pulmonary Nodules |
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| Active, not recruiting | N/A | 10560 | RoW | ctDNA methylation analysis by NGS | AnchorDx Medical Co., Ltd., Xiangya Hospital of Central South University, West China Hospital, Shanghai Zhongshan Hospital, Shanghai Pulmonary Hospital affiliated to Tongji University, First Hospital of China Medical University, Guizhou Provincial People's Hospital, Shanghai Chest Hospital, First Affiliated Hospital, Sun Yat-Sen University, First Affiliated Hospital Xi'an Jiaotong University, Qilu Hospital of Shandong University, Inner Mongolia People's Hospital, The First Affiliated Hospital with Nanjing Medical University, The First Affiliated Hospital of Zhengzhou University, Second Hospital of Jilin University, LanZhou University, Peking University Third Hospital, The First People's Hospital of Yunnan, Shantou Affiliated Hospital of Sun Yat-Sen University, Ruijin Hospital, The Shanghai Jiao Tong University Medical School, Tongji Hospital, The First Affiliated Hospital of Guangzhou Medical University, Xijing Hospital, Air Force Medical University of PLA, Shenzhen People's Hospital, Henan Provincial People's Hospital, Beijing Chao Yang Hospital, Xiamen Second Hospital, The First Affiliated Hospital of Nanchang University | Pulmonary Nodules | 09/24 | 06/25 | | |
NCT05514327: A Study of Ultra-fraction Radiotherapy Bridging CART in R/R DLBCL |
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| Recruiting | N/A | 20 | RoW | ultra-fraction radiotherapy | Peking Union Medical College Hospital | Diffuse Large B Cell Lymphoma, CAR-T, Radiotherapy, Bridging Therapy | 09/24 | 12/24 | | |
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM). |
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| Not yet recruiting | N/A | 1000 | RoW | Continuous Glucose Monitoring System (GX-01S) | Nanjing First Hospital, Nanjing Medical University | Type1 Diabetes Mellitus | 10/26 | 06/27 | | |
NCT04837222: A Study of Brentuximab Vedotin in Adults With CD30-positive Lymphoma |
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| Active, not recruiting | N/A | 1000 | RoW | No Intervention | Takeda | Lymphoma | 06/26 | 06/26 | | |
NCT06723366: Protective Effect of Angong Niuhuang Against Negative Inflammatory Response and Neurologic Dysfunction After Cardiovascular Surgery |
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| Not yet recruiting | N/A | 120 | RoW | Angong Niuhuang Pill (ANP), Control (Standard treatment) | Nanjing Medical University, The First Affiliated Hospital with Nanjing Medical University, Beijing Anzhen Hospital, Capital Medicine University | Cardio-pulmonary Bypass, Cardiovascular Surgery, Cerebral Protection, Brain Injury | 12/25 | 12/25 | | |
NCT05818267: Efficacy and Safety of Regorafenib Maintenance Therapy in Patients With Metastatic Colorectal Cancer (mCRC) |
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| Recruiting | N/A | 30 | RoW | Regorafenib | Wei Zhang | Colorectal Cancer | 03/25 | 11/25 | | |
NCT05282095: Effect of HPV Integration on Prognosis of Young Women With CIN2 in China |
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| Recruiting | N/A | 300 | RoW | Follow up | Fujian Maternity and Child Health Hospital | Cervical Intraepithelial Neoplasia, HPV Infection, Virus Integration, HSIL, High Grade Squamous Intraepithelial Lesions | 12/25 | 05/26 | | |
AIM, NCT05032053: Antithrombotic Drug Use in Patients With Ischemic Stroke and Microbleeds |
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| Recruiting | N/A | 3000 | RoW | Antithrombotic drugs | Xijing Hospital, Ankang Central Hospital, Yan'an University Affiliated Hospital | Ischemic Stroke | 12/25 | 10/26 | | |
LPS-IHH, NCT05569577: An Open Labeled RCT on the Effect of Additional hCG Injection for LPS on Pregnancy Outcomes in IHH Patients |
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| Recruiting | N/A | 46 | RoW | Additional hCG injection, estrogen and dydrogesterone | Fudan University | Luteal Phase Deficiency, Luteal Phase Support, Idiopathic Hypogonadotropic Hypogonadism | 12/25 | 12/25 | | |
NCT05923255: LISH Trial for the Hepatic Flexure and Proximal Transverse Colon Cancer |
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| Recruiting | N/A | 568 | RoW | LISH （Laparoscopic Ileocecal-Sparing Right Hemicolectomy）, TRH（Traditional Laparoscopic Right Hemicolectomy） | Zhejiang University | Hepatic Flexure Colon Cancer, Proximal Transverse Colon Cancer | 05/26 | 05/31 | | |
| Recruiting | N/A | 100000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia | 01/38 | 01/38 | | |
| Recruiting | N/A | 40000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Alzheimer Disease, Familial Alzheimer Disease (FAD) | 01/38 | 01/38 | | |
NCT05409209: Carotid Plaque Length to Predict Cardiovascular Events |
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| Active, not recruiting | N/A | 3000 | RoW | | Changhai Hospital, Putuo Hospital, Shanghai University of Traditional Chinese Medicine, No. 904 Hospital of the PLA Joint Logistics Support Force, Gongli Hospital, Yueyang Hospital, Shanghai University of Traditional Chinese medicine | Coronary Artery Disease | 12/21 | 12/30 | | |
NCT05513664: Real-World Effectiveness of Osimertinib for Patients With Non-Small Cell Lung Cancer |
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| Not yet recruiting | N/A | 80 | RoW | Osimertinib | Shanghai JMT-Bio Inc., CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | Locally Advanced or Metastatic Non-Small Cell Lung Cancer, EGFR Exon20 Insertion Mutations | 06/23 | 08/23 | | |
| Liu, Zheng rong |
NCT05080322: Efficacy and Safety of On-demand and Continuous Administration of Nasal Spray in the Treatment of Allergic Rhinitis |
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| Recruiting | 4 | 150 | RoW | Fluticasone Nasal 50 Mcg/Inh Nasal Spray, Azelastine Nasal 140 Mcg/Inh Nasal Spray, Flixonase,H20140117, AZEP,H20150201, Fluticasone Nasal 50 Mcg/Inh Nasal Spray, Flixonase,H20140117 | Zheng Liu ENT, Wuhan Union Hospital, China, Zhongnan Hospital, The People's Hospital of Hebei Province | Allergic Rhinitis | 12/24 | 01/25 | | |
SAST, NCT04088513: Safety and Efficacy of Aspirin in Stroke Patients With Glucose-6-phosphate Dehydrogenase Deficiency |
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| Recruiting | 4 | 440 | RoW | Aspirin, Acetylsalicylic acid, Clopidogrel, Plavix | First Affiliated Hospital, Sun Yat-Sen University | G6PD Deficiency, Stroke | 12/24 | 12/24 | | |
NCT03431428: Comparison of Short-term Efficacy and Long-term Prognosis for Reduction Surgery and Radical Resection in Almost-cCR Rectal Cancer Patients |
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| Recruiting | 3 | 477 | RoW | transanal surgery, Miles surgery, Preoperative chemoradiotherapy | Zhang Rui | Almost-cCR, Surgery, Rectal Cancer | 01/20 | 12/22 | | |
NCT06200766: A Multicenter, Randomized, Double-blind, Three-arm, Parallel Clinical Endpoint Bioequivalence Study of Monometasone Furoate Nasal Spray in Patients With Seasonal Allergic Rhinitis |
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| Recruiting | 3 | 640 | RoW | Mometasone furoate as a nasal spray | Zheng Liu ENT, Zhejiang Xianju Pharma Tech. Co., Ltd | Seasonal Allergic Rhinitis | 04/24 | 06/24 | | |
NCT06364904: An Phase III Study, Multicenter，Randomized Controlled Trail to Determine the Safety and Efficacy of the Combination of Tislelizumab With Cisplatin and Gemcitabine, With or Without Trilaciclib for Patients With Untreated Unresectable and Metastatic Urothelial Carcinoma. |
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| Not yet recruiting | 3 | 210 | RoW | Tislelizumab, Cisplatin, Gemcitabine and Trilaciclib, Tislelizumab, Cisplatin, Gemcitabine | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Bladder Cancer | 04/27 | 04/29 | | |
NCT05844150: A Study of PM8002 (Anti-PD-L1/VEGF) in Combination With Chemotherapy in Patients With ES-SCLC |
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| Recruiting | 2/3 | 445 | RoW | PM8002, Platinum, Atezolizumab, Etoposide | Biotheus Inc. | SCLC | 06/25 | 12/25 | | |
NCT06315426: A Study of IL4Rα Monoclonal Antibody in Patients With Seasonal Allergic Rhinitis(SAR). |
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| Not yet recruiting | 2 | 90 | NA | GR1802 injection, Placebo | Genrix (Shanghai) Biopharmaceutical Co., Ltd. | Allergic Rhinitis | 10/24 | 12/24 | | |
| Recruiting | 2 | 20 | RoW | zanubrutinib | Xuanwu Hospital, Beijing | Neuromyelitis Optica | 10/24 | 10/24 | | |
NCT06760182: Clinical Trial of TQH2722 Injection in Patients With Seasonal Allergic Rhinitis |
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| Not yet recruiting | 2 | 168 | RoW | TQH2722 injection, TQH2722 Placebo | Shanghai Chia Tai Tianqing Pharmaceutical Technology Development Co., Ltd. | Seasonal Allergic Rhinitis | 06/25 | 08/25 | | |
NCT06364956: Phase Ib/II Trail of Neoadjuvant of Tislelizumab Combined With Palbociclib in Patients With Platinum-refractory Bladder Urothelial Carcinoma |
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| Recruiting | 1/2 | 36 | RoW | Tislelizumab combined with two predefined dose groups of palbociclib, RP2D dose Of Tislelizumab combined with palbociclib was selected for phase II clinical trial. | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Bladder Cancer | 06/25 | 06/26 | | |
NCT05009134: Influences of Allergic Rhinitis and Allergen Immunotherapy on SARS-CoV-2 Vaccination |
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| Recruiting | N/A | 120 | RoW | There is no intervention in this study. | Huazhong University of Science and Technology, National Natural Science Foundation of China | Allergic Rhinitis, Allergen Immunotherapy, SARS-CoV-2 | 03/22 | 04/22 | | |
NCT05983003: Research on Identifying and Treatment Prognosis of Chronic Rhinosinusitis Based on Image and Sequencing Data |
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| Completed | N/A | 3500 | RoW | endoscopic sinus surgery, ESS | Zheng Liu | Chronic Sinusitis, Radiology, Pathology, Surgery, Progression | 04/24 | 04/24 | | |
EMRESSECRS, NCT04852562: The Effect of Modified Radical Endoscopic Sinus Surgery on Eosinopilic Chronic Rhinosinusitus With Nasal Polyps |
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| Recruiting | N/A | 110 | RoW | Modified radical endoscopic sinus surgery, MRESS, functional endoscopic sinus surgery, FESS | Zheng Liu | Chronic Sinusitis, Endoscopic Sinus Surgery, Nasal Polyps | 12/23 | 12/24 | | |
NCT06198894: Steroid-eluting Sinus Stent for Chronic Rhinosinusitis Patients With Uncontrolled Postoperative Symptoms |
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| Recruiting | N/A | 96 | RoW | steroid-eluting sinus stent implant, BISORB bioabsorbable steroid-eluting sinus stent, Systemic glucocorticoids, Medrol, saline irrigations, 0.9% sodium chloride solution, Placebo, Systemic glucocorticoid placebo, sham procedure, In-office bilateral sham procedure of stent placement | Zheng Liu | Chronic Sinusitis | 01/26 | 04/26 | | |
NCT06240104: Monitoring of Heart to Guide Myocardial Injury Patients to Wean From Ventilation |
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| Recruiting | N/A | 200 | RoW | cardiac output index monitor | Peking University People's Hospital | Myocardial Ischaemia During Surgery | 12/25 | 12/25 | | |
NCT06370468: The Epidemiological and Intrinsic Characteristics of Chronic Rhinitis |
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| Recruiting | N/A | 150000 | RoW | Epidemiological investigation | Zheng Liu ENT, Peking Union Medical College, Hainan People's Hospital, Shandong Second Provincial General Hospital, First Affiliated Hospital of Chongqing Medical University, First Affiliated Hospital of Xinjiang Medical University | Chronic Rhinitis | 05/27 | 08/27 | | |
NCT06474923: Multimodal Data-assisted Primary Screening for Allergic Rhinitis Based on Voice Recognition and Face Recognition |
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| Recruiting | N/A | 1500 | RoW | Face image and voice audio | Zheng Liu | Body Image, Speech Sound Disorder | 12/24 | 06/25 | | |
NCT06462417: Efficacy and Safety of Arbidol in the Treatment of Allergic Rhinitis |
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| Not yet recruiting | N/A | 15 | RoW | Arbidol, Arbidol Hydrochloride | Zheng Liu, National Natural Science Foundation of China | Allergic Rhinitis | 06/25 | 06/25 | | |
CATHEDRAL, NCT05134129: Correlation Between Targeted HbA1c Values and Prevention of Recurrent Cardiovascular Events in Type 2 Diabetes After PCI |
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| Recruiting | N/A | 1500 | RoW | | Shanghai 10th People's Hospital | Diabetes Mellitus, Percutaneous Coronary Intervention | 09/24 | 09/24 | | |
NCT05444491: Application of Polygenic Methylation Markers in Postoperative Recurrence Monitoring of Colorectal Cancer |
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| Recruiting | N/A | 1200 | RoW | | Singlera Genomics Inc., Cancer Institute and Hospital, Chinese Academy of Medical Sciences | Colorectal Cancer | 06/25 | 06/25 | | |
| Li, Jianping |
CSPPT2-TT, NCT04974151: China Stroke Primary Prevention Trial 2 for Participants with Hypertension and MTHFR 677 TT Genotype |
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| Recruiting | 4 | 24000 | RoW | Amlodipine besylate, Amlodipine, Amlodipine besylate And Folic Acid, Amlodipine Folic Acid, Anye, 5-methyltetrahydrofolate (5-MTHF), 5-MTHF, Amlodipine placebo, Amlodipine (dummy), Amlodipine folic acid placebo, Amlodipine folic acid (dummy), 5-MTHF Placebos, 5-MTHF (dummy) | Shenzhen Ausa Pharmed Co.,Ltd, Peking University First Hospital, Second Affiliated Hospital of Nanchang University, The First People's Hospital of Lianyungang, The Affiliated Hospital Of Guizhou Medical University, Lianyungang Oriental Hospital, Tengzhou Central People's Hospital, First Affiliated Hospital Bengbu Medical College, H & J CRO International, Inc., Shenzhen Prospective Medical Technology Co., LTD | Hypertension, MTHFR 677 TT Genotype | 06/29 | 06/29 | | |
| Completed | 3 | 226 | Europe, Canada, US, RoW | Bentracimab (PB2452) Infusion | SFJ Pharmaceuticals, Inc. | Hemorrhage, Urgent Surgery, Invasive Procedure | 09/24 | 09/24 | | |
| Recruiting | 3 | 405 | Europe, Canada, US, RoW | Plozasiran Injection, ARO-APOC3, Placebo | Arrowhead Pharmaceuticals | Severe Hypertriglyceridemia | 07/26 | 10/26 | | |
NCT06716970: QR12000 Compound Tablets in Patients with Moderate to Severe Essential Hypertension |
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| Not yet recruiting | 3 | 810 | RoW | QR12000 75mg, QR12000 75mg placebo, QR12000 150mg, QR12000 150mg placebo, Sacubitril/valsartan 200mg, Sacubitril/valsartan 200mg placebo | Wuhan Createrna Science and Technology Co., Ltd | Essential Hypertension | 04/26 | 02/27 | | |
NCT06555640: A Phase II Study to Evaluate the Efficacy and Safety of of DR10624 in Subjects With Severe Hypertriglyceridemia |
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| Recruiting | 2 | 72 | RoW | DR10624 Injection, Placebo | Zhejiang Doer Biologics Co., Ltd. | Severe Hypertriglyceridemia | 08/25 | 10/25 | | |
NCT06048588: YN001 in Healthy Subjects and Patients With Coronary Atherosclerosis |
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| Recruiting | 1/2 | 130 | RoW | YN001, Placebo for YN001, Placebo, rosuvastatin calcium tablets, Crestor® | Beijing Inno Medicine Co., Ltd. | Atherosclerotic Cardiovascular Disease | 12/24 | 04/25 | | |
NCT05509296: Compare the Effectiveness and Safety of Two Different Kinds of Cutting Balloon in Coronary Artery Disease |
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| Completed | N/A | 136 | RoW | SINOMED CBC, cutting balloon catheter, scoring balloon catheter, NSE Coronary Dilatation Catheter, Lacrosse NSE | Sino Medical Sciences Technology Inc., Peking University First Hospital | Coronary Stenosis, Coronary Artery Stenosis, In-stent Restenosis | 11/22 | 11/22 | | |
| Recruiting | N/A | 100 | RoW | Dopamine, Fractional Flow Reserve, Renal, Renal artery stenting | Peking University First Hospital | Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial | 03/25 | 03/25 | | |
FAIR, NCT06447740: Fractional Flow Reserve-guided Stenting Versus Medical Therapy in Atherosclerosis Renal Artery Stenosis |
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| Recruiting | N/A | 200 | RoW | Dopamine, Fractional Flow Reserve, Renal, Renal artery stenting | Peking University First Hospital | Renal Artery Stenosis Atherosclerotic, Secondary Hypertension Renal Arterial | 06/26 | 04/27 | | |
OUFR, NCT06726252: Prospective, Multicenter, Self-controlled Clinical Trial to Validate Optical Ultrasonic Flow Ratio |
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| Recruiting | N/A | 114 | RoW | FFR measurement and intravascular imaging | Harbin Medical University, Peking University Third Hospital, Panovision, Capital Medical University, The Second Affiliated Hospital of Harbin Medical University, The affiliated hospital of Jining medical college, Peking University First Hospital | Fractional Flow Reserve, Coronary Artery Disease | 12/25 | 12/25 | | |
| Not yet recruiting | N/A | 1000 | RoW | SyMapCath I™ catheter and SYMPIONEER S1™ Stimulator/Generator | SyMap Medical (Suzhou), Ltd., Beijing Hisicom Tech Dvpt Inc. | Hypertension, Uncontrolled Hypertension, Resistant Hypertension, Reduce Antihypertensive Drug Burden | 12/28 | 04/29 | | |
NCT05862103: Long-Term Follow-Up in Patients With Acute Myocardial Infarction Cohort |
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| Recruiting | N/A | 15000 | RoW | Treatment Strategies | Yu Bo | Acute Myocardial Infarction, Adverse Event | 08/25 | 12/26 | | |
| Investigator, Principal |
| Completed | 4 | 144 | Europe | Opicapone 50 mg, BIA 9-1067, Placebo | Bial - Portela C S.A., Bial - Portela & Ca, S.A. | Parkinson Disease | 02/24 | 02/24 | | |
NCT04248205: Ketamine for Post-operative Analgesia in Hemorrhoidectomy |
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| Recruiting | 4 | 100 | US | Ketamine | University of Oklahoma | Hemorrhoids | 01/25 | 07/25 | | |
NCT05400369: A Study to Evaluate the Efficacy and Safety of Sitafloxacin in Adult Subjects With Acute Exacerbation of Chronic Obstructive Pulmonary Disease |
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| Completed | 4 | 140 | RoW | Sitafloxacin, Gracevit, Moxifloxacin Hydrochloride, Avelox | Daiichi Sankyo | COPD Exacerbation Acute | 09/24 | 09/24 | | |
TrEAT_TD2, NCT05677282: Single Dose Antibiotic Treatment of Acute Watery Diarrhea, Rifaximin Versus Azithromycin, with Loperamide Adjunct |
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| Recruiting | 4 | 150 | RoW | Rifaximin 550 MG, Azithromycin 500 MG, Loperamide | Henry M. Jackson Foundation for the Advancement of Military Medicine, Infectious Diseases Clinical Research Program, Uniformed Services University of the Health Sciences | Diarrhoea;Acute, Diarrhea Travelers | 09/25 | 12/25 | | |
NCT06397781: Effect of S. Aureus Skin Decolonization on Disease Severity in Atopic Dermatitis Patients |
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| Not yet recruiting | 4 | 100 | US | Skin Cleanser Combination No.1 | Boston Children's Hospital | Atopic Dermatitis | 12/28 | 12/28 | | |
NCT06793358: Use of Remimazolam and Fentanyl for Procedural Sedation in Patients Undergoing Dental Extraction |
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| Not yet recruiting | 4 | 40 | US | fentanyl and Remimazolam | Indiana University, Indiana University Health | Dental Extraction | 01/26 | 03/26 | | |
