Liu, Ling |
NCT04845399: Phase III Expansion Trial for Determining the Safety and Efficacy of Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection in Adolescent and Adult Patients With Hemophilia A |
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| Completed | 3 | 101 | RoW | Recombinant Human Coagulation Factor VIII-Fc Fusion Protein for Injection | Zhengzhou Gensciences Inc, Jiangsu Gensciences lnc. | Hemophilia A | 06/21 | 06/21 | | |
NCT05003570: Efficacy and Safety of Remifentanil for Mechanically Ventilated Patients in ICU |
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| Recruiting | 3 | 138 | RoW | Remifentanil, Remifentanil Hydrochloride for Injection, Fentanyl, Fentanyl Citrate Injection | Southeast University, China | Analgesia | 12/22 | 12/22 | | |
NCT04973670: Protective Effect of Sivelestat Sodium on ARDS in Patients With Sepsis |
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| Recruiting | 3 | 238 | RoW | Sivelestat sodium, Placebo | Southeast University, China | ARDS | 09/23 | 10/23 | | |
SPH3127-301, NCT05359068: Study to Evaluate the Efficacy and Safety of SPH3127 In Patients With Mild-moderate Essential Hypertension |
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| Completed | 3 | 957 | RoW | SPH3127 tablet, Valsartan | Shanghai Pharmaceuticals Holding Co., Ltd | Essential Hypertension | 12/23 | 12/23 | | |
ATNPC, NCT04718701: Anlotinib, Toripalimab and Nab-paclitaxel in Locally Advanced/Metastatic Pancreatic Cancer |
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| Recruiting | 2 | 53 | RoW | Anlotinib+Toripalimab+Nab-paclitaxel, combination therapy | The First Affiliated Hospital with Nanjing Medical University | Pancreatic Neoplasm, Metastatic Pancreatic Cancer, Locally Advanced Pancreatic Adenocarcinoma | 02/23 | 02/23 | | |
NCT06038916: To Evaluate the Safety and Initial Efficacy of STSA-1002 Injection in Patients with Acute Respiratory Distress Syndrome |
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| Recruiting | 1/2 | 60 | RoW | STSA-1002 Injection Placebo, STSA-1002 Injection | Staidson (Beijing) Biopharmaceuticals Co., Ltd | Acute Respiratory Distress Syndrome | 08/25 | 09/26 | | |
NCT06529445: Food Effect and Relative Bioavailability Study of VC004 Capsules in Healthy Adult Subjects |
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| Completed | 1 | 84 | RoW | High Dose VC004 Capsules, Median Dose VC004 Capsules, Low Dose VC004 Capsules | Jiangsu vcare pharmaceutical technology co., LTD | Locally Advanced or Metastatic Solid Tumor Harboring an NTRK Gene Fusion | 08/24 | 08/24 | | |
NCT06619951: A Clinical Trial to Evaluate the Effects of Itraconazole or Rifampicin on the Pharmacokinetics of VC004 Capsules in Healthy Adult Subjects |
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| Completed | 1 | 56 | RoW | VC004 and Itraconazole, VC004 and rifampicin | Jiangsu vcare pharmaceutical technology co., LTD | Locally Advanced or Metastatic Solid Tumor | 10/24 | 10/24 | | |
NCT03842462: NHFOV vs NIPPV vs nCPAP in Preterm Infants With Respiratory Distress Syndrome |
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| Recruiting | N/A | 684 | RoW | nCPAP, NIPPV, NHFOV | Jiulongpo No.1 People's Hospital | Preterm Infant | 05/22 | 05/22 | | |
| Completed | N/A | 57 | RoW | driving pressure guided tidal volume | Southeast University, China | ARDS | 12/22 | 12/22 | | |
| Recruiting | N/A | 210 | RoW | blood mNGS (IDSeqTM Ultra); blood Culture | Southeast University, China, The First Affiliated Hospital with Nanjing Medical University, Northern Jiangsu Province People's Hospital | Sepsis | 12/22 | 12/22 | | |
NCT05372731: Recruitment Maneuver After Bronchoalveolar Lavage in ARDS Patients |
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| Not yet recruiting | N/A | 40 | NA | Recruitment Maneuver | Southeast University, China | Acute Respiratory Distress Syndrome | 12/22 | 12/22 | | |
NCT05219643: Effect of Nava on Weaning Outcome in Patients With Mechanical Ventilation |
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| Recruiting | N/A | 130 | RoW | NAVA, PSV | Southeast University, China, First Affiliated Hospital of Wannan Medical College | ARDS | 12/24 | 02/25 | | |
| Completed | N/A | 10 | RoW | different modes of mechanical ventilation | Southeast University, China | Acute Respiratory Failure | 08/23 | 08/23 | | |
NCT05549882: A Novel Index to Predict the Failure of High-flow Nasal Cannula in Patients With Acute Hypoxemic Respiratory Failure |
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| Recruiting | N/A | 504 | RoW | no intervention | Southeast University, China | Clinical Outcome | 08/23 | 08/23 | | |
NCT05073549: Optimizing Antibiotic Use in Neonatal Intensive Care Units in China |
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| Recruiting | N/A | 10000 | RoW | Collaborative Antimicrobial Stewardship Program (ASP) | Children's Hospital of Fudan University, China Medical Board | Neonates | 09/23 | 12/23 | | |
NCT05989971: The Effect of Continuous Renal Replacement Therapy on the Efficiency of Extracorporeal CO2 Removal |
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| Recruiting | N/A | 10 | RoW | continuous renal replacement therapy | Southeast University, China | Respiratory Failure With Hypercapnia | 12/23 | 12/23 | | |
NCT03345758: Long Term Outcome of Extracorporeal Membrane Oxygenation Patients in China |
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| Recruiting | N/A | 80 | RoW | outcome | Southeast University, China | Long-term Outcome, Extracorporeal Membrane Oxygenation | 12/23 | 12/23 | | |
NCT03763890: Post- End- Expiratory Pressure Affect the Alveolar Heterogeneity in Moderate and Sever ARDS Patients |
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| Recruiting | N/A | 40 | RoW | Post-end-Expiratory pressure | Southeast University, China | Ards | 12/23 | 12/23 | | |
NCT03182023: Long-term Outcome of Patients Treated With Extracorporeal Membrane Oxygenation |
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| Recruiting | N/A | 83 | RoW | | Southeast University, China | Long-term Outcome, Extracorporeal Membrane Oxygenation | 12/23 | 12/23 | | |
NCT05101694: Study on the Correlation Between Alveolar Macrophage-derived Autophagosomes and the Severity of Lung Injury in ARDS |
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| Recruiting | N/A | 60 | RoW | | Southeast University, China | ARDS | 12/23 | 12/23 | | |
NCT06213779: The Burden of Acute Respiratory Failure in Chinese ICUs: a National Cohort Study |
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| Recruiting | N/A | 1500 | RoW | | Southeast University, China | Acute Respiratory Failure, Acute Respiratory Distress Syndrome | 04/24 | 04/25 | | |
| Recruiting | N/A | 45 | RoW | position | Southeast University, China | Acute Respiratory Distress Syndrome, Prone Position, Tidal Volume | 02/25 | 04/25 | | |
NCT06393179: Epidemiology and Treatment Strategy of Open Respiratory Phenotype in Critically Ill Patients |
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| Recruiting | N/A | 60 | RoW | pressure-volume curve with a low-flow insufflation of 5 L/min | Southeast University, China | Mechanical Ventilation Pressure High, Critical Illness | 08/24 | 08/24 | | |
NCT06572280: Non-invasive Phrenic Nerve Stimulation in ARDS Patient |
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| Recruiting | N/A | 10 | RoW | PNS group | Southeast University, China | ARDS, Human, Ventilator-Induced Lung Injury, Diaphragm Injury | 12/24 | 01/25 | | |
NCT05207202: Effect of EIT-guided PEEP Titration on the Prognosis of Patients With Moderate to Severe ARDS |
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| Recruiting | N/A | 376 | RoW | electrical impedance tomography | Southeast University, China | Clinical Outcomes | 12/24 | 12/24 | | |
TRIPOD, NCT06795971: Effects of Face Mask Continuous Positive Airway Pressure vs. Noninvasive Ventilation vs. High-flow Nasal Oxygen on Intubation-free Survival in Acute Hypoxemic Respiratory Failure: The Randomized Clinical Trial |
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| Not yet recruiting | N/A | 1300 | RoW | Continuous Positive Airway Pressure, High-flow nasal oxygen, Non-invasive ventilation | Southeast University, China | Acute Hypoxemic Respiratory Failure, High-Flow Nasal Oxygen Therapy, Noninvasive Ventilation, Continuous Positive Airway Pressure (CPAP) | 10/27 | 12/27 | | |
Liu, Lin |
ERASE, NCT06093191: Tobramycin Inhalation Solution for Pseudomonas Aeruginosa Eradication in Bronchiectasis |
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| Recruiting | 4 | 364 | RoW | Tobramycin Inhalant Product, Inhaled antibiotics, Ciprofloxacin 750 MG, Oral antibiotics, Oral ciprofloxacin placebo, Natural saline inhalation, Inhaled saline | Shanghai Pulmonary Hospital, Shanghai, China | Bronchiectasis Adult, Pseudomonas Aeruginosa Infection | 10/25 | 12/25 | | |
NCT05003245: Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD |
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| Recruiting | 3 | 388 | RoW | HLX04-O,recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection, Lucentis | Shanghai Henlius Biotech | Age Related Macular Degeneration | 08/23 | 03/24 | | |
NCT06708156: The Effectiveness and Safety of Two Low-concentration Atropine Sulfate Eye Drops (0.01%/0.02%) for Delaying the Pediatric Myopia Progression |
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| Recruiting | 3 | 606 | RoW | Atropine sulfate eye drops 0.01%, Atropine sulfate eye drops 0.02%, Placebo eye drops | Oupushifang Pharmaceutical Technology Co., Ltd., Seefunge Pharmaceutical Technology Co., Ltd., AUTEK China Inc. | Myopia, Myopia Progression | 12/26 | 12/27 | | |
NCT04586478: Phase II Clinical Trial of CNCT19 Cell Injection in the Treatment of Relapsed or Refractory Non-Hodgkin's Lymphoma |
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| Recruiting | 2 | 60 | RoW | single dose of CNCT19 | Juventas Cell Therapy Ltd. | Non-Hodgkin's Lymphoma | 12/24 | 09/25 | | |
NCT05807347: Venetoclax Combined With Azacitidine and CAG in Refractory/Relapse Acute Myeloid Leukemia |
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| Recruiting | 2 | 42 | RoW | Venetoclax, Azacitidine, Cytarabine, Aclacinomycin, Granulocyte colony-stimulating factor | Hematology department of the 920th hospital | Refractory/Relapse Acute Myeloid Leukemia | 02/24 | 02/26 | | |
NCT05688696: Evaluate the Efficacy and Safety of Orelabrutinib in Adult Patients With Systemic Lupus Erythematosus |
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| Recruiting | 2 | 186 | RoW | Orelabrutinib (Low Dose), Orelabrutinib (High Dose), Orelabrutinib Placebo | Beijing InnoCare Pharma Tech Co., Ltd. | Systemic Lupus Erythematosus, SLE | 08/25 | 05/26 | | |
| Recruiting | 1/2 | 104 | RoW | Venetoclax in combination with azacitidine and CAG, VA-CAG regimen | Hematology department of the 920th hospital | Acute Myeloid Leukemia | 08/24 | 09/24 | | |
NCT06387082: A Clinical Study of HMPL-506 in Patients With Hematological Malignancies |
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| Recruiting | 1 | 98 | RoW | HMPL-506, Two strengths of HMPL-506 tablets (25 mg and 100 mg) will be used for this clinical study | Hutchmed | Hematological Malignancies | 10/27 | 12/27 | | |
NCT04606433: Phase I Clinical Study of GNC-038 in Patients With Non-Hodgkin's Lymphoma or Acute Lymphoblastic Leukemia |
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| Recruiting | 1 | 41 | RoW | GNC-038 | Sichuan Baili Pharmaceutical Co., Ltd., SystImmune Inc. | Non Hodgkin Lymphoma, Acute Lymphoblastic Leukemia | 06/25 | 11/25 | | |
NCT06702683: The Correlation Between Blood Concentration of Sintilimab and Efficacy and Adverse Reactions in Patients with Advanced Gastric Cancer |
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| Recruiting | N/A | 112 | RoW | | Lin Liu | Gastric Carcinoma, Gastric Neoplasm, Gastric (cardia, Body) Cancer, Gastric Cancer Adenocarcinoma Metastatic | 06/25 | 12/25 | | |
NCT06164821: Clinical Observation of Luspatercept in Treatment of Chinese Adult β-thalassaemia Patients With TD β-thalassemia |
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| Recruiting | N/A | 10 | RoW | luspatercept | Hematology department of the 920th hospital | Effect of Drug | 01/24 | 11/24 | | |
NCT05485103: A Prospective Study of the Effect of Modified Colonoscopy Bowel Preparation Program on Intestinal Cleaning, Examination and Disease in Patients With Inflammatory Bowel Disease |
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| Recruiting | N/A | 144 | RoW | Polyethylene Glycols, glycerin enema, asol | Peking Union Medical College Hospital | Inflammatory Bowel Diseases | 07/24 | 12/24 | | |
NCT05243836: S.T.O.P.® Technology Contact Lenses Versus Dual-focus Contact Lenses for Slowing Down Myopia Progression in Children |
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| Recruiting | N/A | 441 | Europe, RoW | S.T.O.P® F2, S.T.O.P® DT, MiSight® | nthalmic Pty Ltd, Brighten Optix Corporation | Myopia | 01/28 | 01/28 | | |