| Rivera, Jose Arturo Rodriguez |
| Active, not recruiting | 3 | 417 | US | SB-01 For Injection, Sham Needle | Spine BioPharma, Inc, MCRA | Lumbar Degenerative Disc Disease | 02/25 | 08/25 | | |
| Terminated | 2b | 98 | Europe, Canada, US, RoW | EDP-305 1.5 mg, EDP-305, EDP-305 2 mg, Placebo | Enanta Pharmaceuticals, Inc, Enanta Pharmaceuticals, Inc. | Non-Alcoholic Steatohepatitis | 10/21 | 11/21 | | |
NCT04042844: A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD) |
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| Recruiting | 2 | 99 | US | BRTX-100, Saline | BioRestorative Therapies | Lumbar Disc Disease | 08/24 | 08/25 | | |
| Recruiting | N/A | 264 | Europe | MULTIDOMAIN NUTRITIONAL INTERVENTION: DIET, EXERCISE AND NUTRITIONAL SUPPLEMENTS, NUTRITION TEAM, CONTROL | Spanish Society of Cardiology | Heart Failure | 09/24 | 12/24 | | |
NCT06419855: Study to Evaluate the Effectivity and Safety of BIOSCAFF®H Compared to DuraGen®, in Patients Undergoing Dural Repair |
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| Recruiting | N/A | 86 | RoW | Human collagen matrix graft, Bovine collagen matrix graft | Top Health S.A.P.I DE C.V., CLINICAL RESEARCH PS MEXICO | Cerebrospinal Fluid Leakage | 08/26 | 12/26 | | |
| Langhorst, Meredith |
| Active, not recruiting | 3 | 417 | US | SB-01 For Injection, Sham Needle | Spine BioPharma, Inc, MCRA | Lumbar Degenerative Disc Disease | 02/25 | 08/25 | | |
| Recruiting | N/A | 500 | US | VIA Disc NP | VIVEX Biologics, Inc., Moxie Clinical | Discogenic Pain, Back Pain, Back Pain, Low | 01/27 | 01/27 | | |
RESTORE, NCT04803214: ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation |
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| Active, not recruiting | N/A | 203 | US | ReActiv8 | Mainstay Medical | Chronic Low-back Pain | 09/24 | 01/26 | | |
| Terminated | N/A | 83 | US | VIA Disc NP (HCT/P) | VIVEX Biologics, Inc., Talosix | Discogenic Pain, Back Pain, Back Pain, Low | 03/24 | 03/24 | | |
| Glover, Melanie |
| Active, not recruiting | 3 | 417 | US | SB-01 For Injection, Sham Needle | Spine BioPharma, Inc, MCRA | Lumbar Degenerative Disc Disease | 02/25 | 08/25 | | |
NCT05333211: Ortho-R® for Rotator Cuff Repair Compared With Standard of Care Rotator Cuff Repair Without Ortho-R® |
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| Recruiting | 1/2 | 78 | US | Ortho-R/PRP | ChitogenX Inc, MCRA | Rotator Cuff Tears | 12/23 | 05/24 | | |
MAGIC, NCT05361941: Multicenter Trial of Antibiotic Eluting Graft for Promoting New Bone Growth In/near Infected Bone Cavities |
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| Recruiting | N/A | 204 | US | EP Granules with Tobramycin, empty voids | Elute, Inc. | Periprosthetic Joint Infections | 12/25 | 12/25 | | |
| Recruiting | N/A | 500 | US | VIA Disc NP | VIVEX Biologics, Inc., Moxie Clinical | Discogenic Pain, Back Pain, Back Pain, Low | 01/27 | 01/27 | | |
| Recruiting | N/A | 300 | US | CERAMENT BVF | BONESUPPORT AB | Orthopedic Disorder | 03/25 | 03/25 | | |
RESTORE, NCT04803214: ReActiv8 Stimulation Therapy vs Optimal Medical Management: A Randomized Evaluation |
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| Active, not recruiting | N/A | 203 | US | ReActiv8 | Mainstay Medical | Chronic Low-back Pain | 09/24 | 01/26 | | |
| Recruiting | N/A | 1000 | US | Follow-up schedule: pre-operative baseline up to 24-months post-procedure | Medtronic Spinal and Biologics, Medtronic Bakken Research Center | Spinal Deformity, Spinal Degenerative Disorder, Spinal Fusion Failure, Spinal Trauma, Spinal Tumor Case | 05/31 | 05/31 | | |
| Terminated | N/A | 83 | US | VIA Disc NP (HCT/P) | VIVEX Biologics, Inc., Talosix | Discogenic Pain, Back Pain, Back Pain, Low | 03/24 | 03/24 | | |
| Wood, Emily H |
| Active, not recruiting | 3 | 417 | US | SB-01 For Injection, Sham Needle | Spine BioPharma, Inc, MCRA | Lumbar Degenerative Disc Disease | 02/25 | 08/25 | | |
NCT06156865: Using Neuroimaging and Behavioral Assessments to Understand Late Talking |
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| Recruiting | N/A | 45 | Canada | Intervention to address late talking | University of Toronto, Holland Bloorview Kids Rehabilitation Hospital, Children's Hospital Medical Center, Cincinnati, University of Cincinnati, Georgetown University | Developmental Language Disorder, Language Delay, Language Development | 04/25 | 06/25 | | |
| Guirguis, Robert |
| Active, not recruiting | 3 | 417 | US | SB-01 For Injection, Sham Needle | Spine BioPharma, Inc, MCRA | Lumbar Degenerative Disc Disease | 02/25 | 08/25 | | |
NCT04042844: A Single Dose of BRTX 100 for Patients With Chronic Lumbar Disc Disease (cLDD) |
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| Recruiting | 2 | 99 | US | BRTX-100, Saline | BioRestorative Therapies | Lumbar Disc Disease | 08/24 | 08/25 | | |
| Tandeski, Kendra |
| Active, not recruiting | 3 | 417 | US | SB-01 For Injection, Sham Needle | Spine BioPharma, Inc, MCRA | Lumbar Degenerative Disc Disease | 02/25 | 08/25 | | |
Polaris-AD, NCT05531526: Phase 3, Double-blind, Randomized, Placebo-controlled Trial to Evaluate the Efficacy and Safety of AR1001 in Participants with Early Alzheimer's Disease |
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| Recruiting | 3 | 1150 | Europe, US, RoW | AR1001, Placebo | AriBio Co., Ltd. | Alzheimer Disease | 12/25 | 12/27 | | |
