| MA, Brigette |
NRG-HN007, NCT04458909: Testing the Addition of an Anti-cancer Immune Therapy Drug (Nivolumab) to the Usual Chemotherapy Treatment (Cisplatin or Carboplatin With Gemcitabine) for Recurrent or Metastatic Nasopharyngeal Cancer |
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| Terminated | 3 | 15 | Canada, US, RoW | Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Gemcitabine, dFdC, dFdCyd, Difluorodeoxycytidine, Nivolumab, ABP 206, BMS-936558, CMAB819, MDX-1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar CMAB819, ONO-4538, Opdivo, Questionnaire Administration | National Cancer Institute (NCI), NRG Oncology | Metastatic Nasopharyngeal Carcinoma, Metastatic Nasopharyngeal Keratinizing Squamous Cell Carcinoma, Metastatic Nasopharyngeal Nonkeratinizing Carcinoma, Metastatic Nasopharyngeal Undifferentiated Carcinoma, Nasopharyngeal Nonkeratinizing Carcinoma, Recurrent Nasopharyngeal Carcinoma, Recurrent Nasopharyngeal Keratinizing Squamous Cell Carcinoma, Recurrent Nasopharyngeal Undifferentiated Carcinoma, Stage IV Nasopharyngeal Carcinoma AJCC v8, Stage IVA Nasopharyngeal Carcinoma AJCC v8, Stage IVB Nasopharyngeal Carcinoma AJCC v8 | 08/23 | 08/23 | | |
NCT03997435: FOLFOXIRI With or Without Intensification for Rectal Cancer |
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| Recruiting | 2 | 72 | RoW | Control arm, Experimental arm | CCTU | Rectal Cancer | 12/25 | 12/26 | | |
| Active, not recruiting | 2 | 40 | RoW | neoadjuvant FOLFOXIRI, Capecitabine | Chinese University of Hong Kong | Rectal Cancer | 12/25 | 12/26 | | |
REMAIN, NCT06029270: Testing the Addition of BMS-986016 (Relatlimab) to the Usual Immunotherapy After Initial Treatment for Recurrent or Metastatic Nasopharyngeal Cancer |
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| Recruiting | 2 | 156 | Canada, US, RoW | Biospecimen Collection, Biological Sample Collection, Biospecimen Collected, Specimen Collection, Bone Scan, Bone Scintigraphy, Carboplatin, Blastocarb, Carboplat, Carboplatin Hexal, Carboplatino, Carboplatinum, Carbosin, Carbosol, Carbotec, CBDCA, Displata, Ercar, JM-8, JM8, Nealorin, Novoplatinum, Paraplatin, Paraplatin AQ, Paraplatine, Platinwas, Ribocarbo, Cisplatin, Abiplatin, Blastolem, Briplatin, CDDP, Cis-diammine-dichloroplatinum, Cis-diamminedichloridoplatinum, Cis-diamminedichloro Platinum (II), Cis-diamminedichloroplatinum, Cis-dichloroammine Platinum (II), Cis-platinous Diamine Dichloride, Cis-platinum, Cis-platinum II, Cis-platinum II Diamine Dichloride, Cismaplat, Cisplatina, Cisplatinum, Cisplatyl, Citoplatino, Citosin, Cysplatyna, DDP, Lederplatin, Metaplatin, Neoplatin, Peyrone's Chloride, Peyrone's Salt, Placis, Plastistil, Platamine, Platiblastin, Platiblastin-S, Platinex, Platinol, Platinol- AQ, Platinol-AQ, Platinol-AQ VHA Plus, Platinoxan, Platinum, Platinum Diamminodichloride, Platiran, Platistin, Platosin, Computed Tomography, CAT, CAT Scan, Computed Axial Tomography, Computerized Axial Tomography, Computerized axial tomography (procedure), Computerized Tomography, Computerized Tomography (CT) scan, CT, CT Scan, tomography, Gemcitabine, dFdC, dFdCyd, Difluorodeoxycytidine, Magnetic Resonance Imaging, Magnetic Resonance, Magnetic Resonance Imaging (MRI), Magnetic resonance imaging (procedure), Magnetic Resonance Imaging Scan, Medical Imaging, Magnetic Resonance / Nuclear Magnetic Resonance, MR, MR Imaging, MRI, MRI Scan, MRIs, NMR Imaging, NMRI, Nuclear Magnetic Resonance Imaging, sMRI, Structural MRI, Nivolumab, ABP 206, BCD-263, BMS 936558, BMS-936558, BMS936558, CMAB819, MDX 1106, MDX-1106, MDX1106, NIVO, Nivolumab Biosimilar ABP 206, Nivolumab Biosimilar BCD-263, Nivolumab Biosimilar CMAB819, ONO 4538, ONO-4538, ONO4538, Opdivo, Positron Emission Tomography, Medical Imaging, Positron Emission Tomography, PET, PET Scan, Positron emission tomography (procedure), Positron Emission Tomography Scan, Positron-Emission Tomography, proton magnetic resonance spectroscopic imaging, PT, Relatlimab, BMS 986016, BMS-986016, BMS986016, Immunoglobulin G4, Anti-(human Lymphocyte Activation Gene-3 Protein) (Human Heavy Chain), Disulfide with Human Light Chain, Dimer | National Cancer Institute (NCI) | Metastatic Nasopharyngeal Carcinoma, Recurrent Nasopharyngeal Carcinoma, Stage IV Nasopharyngeal Carcinoma AJCC v8 | 04/29 | 04/29 | | |
| Active, not recruiting | 1/2 | 323 | US, RoW | FLX475, pembrolizumab (KEYTRUDA®) | RAPT Therapeutics, Inc., Merck Sharp & Dohme LLC | Advanced Cancer | 09/24 | 01/25 | | |
| Recruiting | N/A | 200 | RoW | NGS, PDO/PDX establishment | Brigette Ma | Gastrointestinal Cancers | 12/25 | 12/26 | | |
| Chan, Helen SL |
NCT00110110: Combination Chemotherapy and Cyclosporine Followed by Focal Therapy for Bilateral Retinoblastoma |
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| Active, not recruiting | 2 | 71 | Canada, RoW | filgrastim, granulocyte colony-stimulating factor (G-CSF), Carboplatin, Cyclosporine, Etoposide, vincristine sulfate, vincristine, cryosurgery, cryotherapy, laser therapy | The Hospital for Sick Children, Terry Fox Foundation | Retinoblastoma | 04/16 | 12/24 | | |
| Recruiting | N/A | 164 | RoW | mHealth-supported coaching, Conventional Health coaching | Food and Health Bureau, Hong Kong | Heart Disease Risk Factors | 06/24 | 09/24 | | |
NCT05370352: Mobile Chat Messaging for Smoking Relapse Prevention |
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| Active, not recruiting | N/A | 590 | RoW | Standard smoking cessation treatment, Personalised chat messaging, SMS text messaging | The University of Hong Kong, Health and Medical Research Fund, Tung Wah Group of Hospitals Integrated Centre on Smoking Cessation, United Christian Nethersole Community Health Service Smoking Cessation Programme | Smoking Cessation | 03/25 | 09/25 | | |
NCT06008210: A Decision Aid on End-of-life Care for Patients With Advanced COPD and Their Family |
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| Recruiting | N/A | 226 | RoW | Decision Support Intervention, Health Coaching | Food and Health Bureau, Hong Kong, Hospital Authority, Hong Kong | Chronic Obstructive Pulmonary Disease Severe | 05/25 | 05/25 | | |
| WONG, Vincent W |
NCT04241575: Identification of Fatty Liver With Advanced Fibrosis in Type 2 Diabetes Using Simple Fibrosis Scores and Electronic Reminder Messages |
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| Completed | N/A | 1061 | RoW | Simple fibrosis scores and electronic reminder messages | Chinese University of Hong Kong | Fatty Liver, Nonalcoholic, Diabetes Mellitus, Type 2 | 10/22 | 01/23 | | |
NCT05704504: Incorporating Ecological Momentary Assessment and Personalized Telephone Support Into Group-Based Exercise Intervention for Depressive Symptoms |
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| Recruiting | N/A | 60 | RoW | Group-based exercise intervention with EMA and personalized telephone support (SUP), Group-based exercise intervention (EXE) | Chinese University of Hong Kong | Depression | 10/23 | 12/23 | | |
NCT06203548: Monitoring Changes in Hepatic Steatosis Using Continuous Controlled Attenuation Parameter |
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| Recruiting | N/A | 150 | RoW | Lifestyle modification programme | Chinese University of Hong Kong | Fatty Liver | 01/27 | 04/27 | | |
NCT05454761: Multicomponent Lifestyle Intervention for Depression Supported With Digital Health Technologies to Promote Adherence |
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| Recruiting | N/A | 141 | RoW | Group-based Lifestyle Medicine Program | Chinese University of Hong Kong | Depression | 09/24 | 12/24 | | |
NCT06549673: Safety of Discontinuing NSBBs in Cirrhotic Patients With Managed Primary Aetiological Factors |
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| Not yet recruiting | N/A | 375 | NA | | Chinese University of Hong Kong | Portal Hypertension, Cirrhosis, Varices, Esophageal | 12/27 | 12/31 | | |
| Not yet recruiting | N/A | 1800 | Europe, RoW | Digital Pathology FibroNest Phenotypic Fibrosis Composite Score (Ph-FCS) | PharmaNest, Inc, Chinese University of Hong Kong, University of Edinburgh, University of Seville, Imperial College London, Icahn School of Medicine at Mount Sinai, Fundacio Clinic Barcelona, Sorbonne University, Newcastle University | Metabolic Dysfunction-associated Steatotic Liver Disease | 05/25 | 07/25 | | |
NCT03282305: Great China Fatter Liver Consortium (GC_FLC) Study to Assess the Progress of NAFLD/NASH in Chinese |
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| Not yet recruiting | N/A | 5000 | NA | | Great China Fatty Liver Consortium Limited, Chinese University of Hong Kong, Virginia Commonwealth University | Nonalcoholic Fatty Liver, Nonalcoholic Steatohepatitis | 12/28 | 12/29 | | |
| Kwok, Timothy CY |
| Active, not recruiting | 4 | 134 | RoW | Trazodone, Placebo | Chinese University of Hong Kong, Hong Kong University of Science and Technology | Mild Cognitive Impairment, Obstructive Sleep Apnea | 05/25 | 12/25 | | |
NCT04709393: Effects of FRAX+SARC-F Pre-screening on Preventing Fragility Fracture and Fall in Community-dwelling Older Adults |
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| Active, not recruiting | N/A | 2956 | RoW | FRAX+SARC-F questionnaire pre-screening | Chinese University of Hong Kong | Age Related Osteoporosis, Fall | 12/23 | 12/28 | | |
| Active, not recruiting | N/A | 250 | RoW | | Chinese University of Hong Kong, Hong Kong University of Science and Technology | Alzheimer Disease | 11/24 | 12/24 | | |
NCT06573658: Neurophysiological Changes After Perturbation-based Training in Older Adults |
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| Recruiting | N/A | 88 | RoW | Perturbation-based balance training (PBT), Active control (control) | The Hong Kong Polytechnic University | Healthy Subjects, Postural Balance, Falling | 10/25 | 10/26 | | |
NCT05525039: RCT of Combination Effect of Vibration Treatment and HMB Supplementation on Myosteatosis and NMJ Degeneration |
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| Recruiting | N/A | 200 | RoW | Low-magnitude High-frequency Vibration, Vibration Treatment, β-hydroxy β-methylbutyrate (HMB) supplement, Protein supplement | Chinese University of Hong Kong, Abbott | Sarcopenia, Connective Tissue Diseases in Old Age, Musculoskeletal Abnormalities | 10/24 | 04/25 | | |
iLiFE, NCT05694494: Training- and Cost-effectiveness of an Internet-based Lifestyle-integrated Functional Exercise Program |
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| Enrolling by invitation | N/A | 322 | RoW | internet-based Lifestyle-integrated Functional Exercise (iLiFE), upper limb exercise training | Chinese University of Hong Kong | Fall | 11/25 | 11/25 | | |
| Recruiting | N/A | 500 | RoW | | Chinese University of Hong Kong | Alzheimer Disease | 12/27 | 12/27 | | |
| Ko, Fanny WS |
NCT02815761: A Prospective Study Readmission and Mortality of COPD Patients |
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| Recruiting | N/A | 800 | RoW | NO intervention, just observation | Chinese University of Hong Kong | COPD | 12/25 | 12/25 | | |
NCT03272932: Clinical Characteristics of Asthma and COPD Overlap for Patients With Asthma and COPD in Hong Kong |
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| Recruiting | N/A | 1600 | RoW | No intervention | Chinese University of Hong Kong | COPD, Asthma | 12/25 | 12/25 | | |
NCT06196034: Genetic Association With Various Severities, Phenotypes and Endotypes of Asthma. |
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| Recruiting | N/A | 2000 | RoW | No intervention | Chinese University of Hong Kong | Asthma | 01/28 | 01/29 | | |
NCT06778746: Use of Biologics for Severe Asthma in Hong Kong |
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| Recruiting | N/A | 360 | RoW | no interventions, No interventions, this is an observational study | Chinese University of Hong Kong | Asthma | 12/25 | 12/26 | | |
NCT04706988: Relationship of Airway Microbiota, Endotype and Phenotype in Adult Asthma |
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| Recruiting | N/A | 140 | RoW | Treatment of asthma according to GINA guideline | Chinese University of Hong Kong | Asthma | 12/24 | 12/24 | | |
NCT04639791: To Assess the Management of Patients on Global Initiative of Asthma (GINA) Step 4 and 5 Treatment in Hong Kong |
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| Recruiting | N/A | 500 | RoW | No intervention | Chinese University of Hong Kong | Asthma | 12/25 | 12/25 | | |
NCT05825014: Predicting Adverse Outcomes Using Machine Learning of COPD Patients in Hong Kong |
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| Recruiting | N/A | 100000 | RoW | No intervention | Chinese University of Hong Kong | COPD Exacerbation | 04/26 | 04/27 | | |
| Hui, David S |
NCT05228418: Bridging ED to Outpatient AUD Therapy With Naltrexone |
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| Not yet recruiting | 4 | 20 | US | Naltrexone Pill, naltrexone IM 380mg | Albert Einstein Healthcare Network | Alcohol Use Disorder | 12/24 | 07/25 | | |
NCT04188418: Fentanyl Buccal Tablet or Morphine for Exertional Dyspnea in Cancer Patients |
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| Active, not recruiting | 3 | 150 | US | Fentanyl Citrate Buccal Tablet, Fentora, Morphine, Physical Performance Testing, Physical Fitness Testing, Physical Function Testing, Placebo Administration, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Hematopoietic and Lymphoid Cell Neoplasm, Malignant Solid Neoplasm | 08/25 | 08/25 | | |
NCT03901001: Adjunctive Sirolimus and Oseltamivir Versus Oseltamivir Alone for Treatment of Influenza |
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| Recruiting | 3 | 160 | RoW | sirolimus and oseltamivir, Oseltamivir | Chinese University of Hong Kong | Influenza | 10/25 | 12/25 | | |
NCT03900988: Intravenous N-acetylcysteine and Oseltamivir Versus Oseltamivir in Adults Hospitalized With Influenza and Pneumonia |
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| Recruiting | 3 | 160 | RoW | N-acetyl cysteine, 5% Dextrose | Chinese University of Hong Kong | Influenza | 10/25 | 12/25 | | |
R21NR016736, NCT03021486: Haloperidol With or Without Chlorpromazine in Treating Delirium in Patients With Advanced, Metastatic, or Recurrent Cancer |
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| Active, not recruiting | 2/3 | 70 | US | Chlorpromazine, Chlor-PZ, Thorazine, Haloperidol, Haldol, McN-JR-1625, R 1625, R-1625, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI), National Institutes of Health (NIH), National Institute of Nursing Research (NINR) | Advanced Malignant Neoplasm, Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm | 06/21 | 06/25 | | |
NCI-2018-02438, NCT03743649: Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care |
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| Active, not recruiting | 2/3 | 110 | US, RoW | Haloperidol, Haldol, McN-JR-1625, R 1625, R-1625, Lorazepam, Ativan, Placebo, placebo therapy, PLCB, sham therapy, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm | 12/25 | 12/26 | | |
NCT06336642: Structured Personalized Oxygen and Supportive Therapies for Dyspnea in Oncology |
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| Recruiting | 2/3 | 150 | US | SPOT-ON Early Start, SPOT-ON Delayed Start | M.D. Anderson Cancer Center | Dyspnea | 03/30 | 03/32 | | |
NCT05431595: Managing Agitated Delirium with Neuroleptics and Anti-Epileptics As a Neuroleptic Sparing Strategy |
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| Recruiting | 2/3 | 30 | US | Haloperidol, Chlorpromazine, Chlorpromazine hydrochloride, Thorazine®, Valproate, Depakene, Valproate Acid, Placebo | M.D. Anderson Cancer Center, Cancer Prevention Research Institute of Texas | Delirium, Epileptics, Neuroleptics | 02/27 | 02/27 | | |
NCT05766124: Trial of Reduced Alteplase Dose for Parapneumonic Effusion (TRAPPE) |
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| Not yet recruiting | 2/3 | 30 | NA | Tissue Plasminogen Activator, Alteplase | Chinese University of Hong Kong | Pleural Infection | 03/28 | 06/28 | | |
NCT01949662: Haloperidol and Lorazepam for Delirium in Patients With Advanced Cancer |
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| Active, not recruiting | 2 | 93 | US | Lorazepam, Placebo, Haloperidol decanoate, Questionnaires, Surveys | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Advanced Cancers | 08/16 | 01/26 | | |
NCT02357134: High-Flow Oxygen in Reducing Shortness of Breath Caused by Exercise in Patients With Cancer |
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| Active, not recruiting | 2 | 74 | US | Oxygen Therapy, supplemental oxygen therapy, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Respiratory Therapy | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Dyspnea, Malignant Neoplasm | 12/20 | 05/23 | | |
| Active, not recruiting | 2 | 135 | US | Dexamethasone, Aacidexam, Adexone, Aknichthol Dexa, Alba-Dex, Alin, Alin Depot, Alin Oftalmico, Amplidermis, Anemul mono, Auricularum, Auxiloson, Baycadron, Baycuten, Baycuten N, Cortidexason, Cortisumman, Decacort, Decadrol, Decadron, Decadron DP, Decalix, Decameth, Decasone R.p., Dectancyl, Dekacort, Deltafluorene, Deronil, Desamethasone, Desameton, Dexa-Mamallet, Dexa-Rhinosan, Dexa-Scheroson, Dexa-sine, Dexacortal, Dexacortin, Dexafarma, Dexafluorene, Dexalocal, Dexamecortin, Dexameth, Dexamethasone Intensol, Dexamethasonum, Dexamonozon, Dexapos, Dexinoral, Dexone, Dinormon, Fluorodelta, Fortecortin, Gammacorten, Hexadecadrol, Hexadrol, Lokalison-F, Loverine, Methylfluorprednisolone, Millicorten, Mymethasone, Orgadrone, Spersadex, TaperDex, Visumetazone, ZoDex, Placebo, placebo therapy, PLCB, sham therapy, Questionnaire Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Dyspnea, Malignant Neoplasm | 05/21 | 12/25 | | |
NCT02932332: High-Flow Oxygen for Dyspnea in Hospitalized Cancer Patients |
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| Completed | 2 | 26 | US | High-flow Oxygen, HFOx, Low-flow Oxygen, LFOx, High-flow Air, HFAir, Low-flow Air, LFAir | M.D. Anderson Cancer Center | Cancer | 03/23 | 03/23 | | |
| Completed | N/A | 132 | RoW | Observation, no intervention, No intervention | Chinese University of Hong Kong | Asthma | 12/22 | 12/22 | | |
NCT03043378: Chronic Non-Malignant Pain in Cancer Patients at a Supportive Care Clinic |
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| Completed | N/A | 201 | US | Questionnaires, Surveys | M.D. Anderson Cancer Center | Malignant Neoplasms of Independent (Primary) Multiple Sites | 03/23 | 03/23 | | |
NCT05058339: Distress Associated with Coronavirus Disease 2019 and Telehealth on Supportive Care Patients with Advanced Cancer |
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| Completed | N/A | 223 | US | Survey Administration | M.D. Anderson Cancer Center | Advanced Malignant Solid Neoplasm, COVID-19 Infection, Hematopoietic and Lymphoid Cell Neoplasm, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Hematologic Malignancy, Recurrent Malignant Solid Neoplasm | 09/24 | 09/24 | | |
NCT06196034: Genetic Association With Various Severities, Phenotypes and Endotypes of Asthma. |
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| Recruiting | N/A | 2000 | RoW | No intervention | Chinese University of Hong Kong | Asthma | 01/28 | 01/29 | | |
NCT04989556: Technology-Enhanced Palliative Care for Advanced Cancer Patients |
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| Active, not recruiting | N/A | 119 | US | Interview, Palliative Therapy, Comfort Care, PA-Palliative Therapy, palliation, Palliative, Palliative Care, Palliative Treatment, Symptom Management, Symptoms Management, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration | M.D. Anderson Cancer Center | Advanced Malignant Solid Neoplasm | 05/26 | 05/26 | | |
| Enrolling by invitation | N/A | 400 | RoW | Survey | Chinese University of Hong Kong | Pleural Effusion, Tuberculosis, Pleural | 11/24 | 02/25 | | |
NCT04611243: Lung Function, Exercise Capacity, and Serology Responses in Patients With COVID-19 |
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| Recruiting | N/A | 700 | RoW | third dose vaccination with CoronaVac vaccine, third dose vaccination with BionTech vaccine, Vaccination with Coronavac vaccine, Vaccination with BionTech Vaccine | Chinese University of Hong Kong, The University of Hong Kong, Health and Medical Research Fund | Lung Function, Exercise Capacity, Quality of Life, Covid19 | 08/25 | 02/26 | | |
NCT06563167: Detection and Prediction of Clinically Significant Pneumothorax After Image-guided Transthoracic Lung Biopsy |
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| Not yet recruiting | N/A | 330 | RoW | CXR | Chinese University of Hong Kong | Lung Biopsy | 12/24 | 12/25 | | |
| Recruiting | N/A | 62 | RoW | Mycobacterium tuberculosis (MTB) cell-free DNA (cf-DNA), Mycobacterium tuberculosis PCR | Chinese University of Hong Kong | Tuberculosis, Pleural | 09/24 | 09/25 | | |
NCT05095948: Improving Processes of Cancer Care Delivery at a Comprehensive Cancer Center |
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| Not yet recruiting | N/A | 200 | US | Discussion, Discuss, Electronic Health Record Review, Questionnaire Administration | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Metastatic Malignant Solid Neoplasm | 09/26 | 09/26 | | |
NCT06778746: Use of Biologics for Severe Asthma in Hong Kong |
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| Recruiting | N/A | 360 | RoW | no interventions, No interventions, this is an observational study | Chinese University of Hong Kong | Asthma | 12/25 | 12/26 | | |
NCT04706988: Relationship of Airway Microbiota, Endotype and Phenotype in Adult Asthma |
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| Recruiting | N/A | 140 | RoW | Treatment of asthma according to GINA guideline | Chinese University of Hong Kong | Asthma | 12/24 | 12/24 | | |
NCT05351515: Prevalence of Non-alcoholic Fatty Liver Disease Among Non-obese Obstructive Sleep Apnea by Using Transient Elastography |
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| Recruiting | N/A | 1000 | RoW | | Chinese University of Hong Kong | Sleep Apnea, Obstructive, Fatty Liver | 01/25 | 01/25 | | |
NCT06796647: ESAT6/CFP10 Skin Testing for TB Infection in Rheumatologic Patients |
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| Not yet recruiting | N/A | 100 | RoW | ESAT6/CFP10 skin test | Chinese University of Hong Kong | Tuberculosis (TB) | 02/28 | 08/28 | | |
| Not yet recruiting | N/A | 350 | RoW | | Chinese University of Hong Kong | Tuberculosis, Pleural | 02/26 | 02/26 | | |
NCT05569629: Bronchial Washing Beforeand After Endobronchial Biopsy and Bronchial Brushing |
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| Completed | N/A | 118 | RoW | Bronchial washing before endobronchial biopsy and brushing | Chinese University of Hong Kong | Lung Cancer | 10/23 | 06/24 | | |
NCT06722846: Communicating Health Options to Inform Care and Empower Strategic Care Planning (CHOICES): A Multi-layer Randomized Case Vignette Study. |
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| Not yet recruiting | N/A | 400 | US | Randomized Case Vignette Study | M.D. Anderson Cancer Center | Health Options, Strategic Care Planning | 08/26 | 08/28 | | |
NCT04639791: To Assess the Management of Patients on Global Initiative of Asthma (GINA) Step 4 and 5 Treatment in Hong Kong |
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| Recruiting | N/A | 500 | RoW | No intervention | Chinese University of Hong Kong | Asthma | 12/25 | 12/25 | | |
NCT05759117: Prospective Evaluation of Patients With Pleural Effusion |
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| Recruiting | N/A | 1000 | RoW | thoracentesis, chest drain insertion | Chinese University of Hong Kong | Pleural Effusion | 03/26 | 03/26 | | |
NCT05825014: Predicting Adverse Outcomes Using Machine Learning of COPD Patients in Hong Kong |
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| Recruiting | N/A | 100000 | RoW | No intervention | Chinese University of Hong Kong | COPD Exacerbation | 04/26 | 04/27 | | |
NCT05091632: Assessment of Verbal Comprehension and Cognitive Processes in Patients Admitted to the Palliative and Supportive Care Unit |
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| Suspended | N/A | 30 | US | Electroencephalography, EEG, electroencephalogram, Questionnaire Administration | M.D. Anderson Cancer Center | Hematopoietic and Lymphoid Cell Neoplasm, Locally Advanced Malignant Solid Neoplasm, Metastatic Malignant Solid Neoplasm, Recurrent Malignant Solid Neoplasm | 02/27 | 02/27 | | |
| Chan, Juliana CN |
NCT05268237: Safety, Tolerability and Preliminary Efficacy of Sublingual Liraglutide in Patients With Type 2 Diabetes Mellitus |
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| Recruiting | 1/2 | 15 | RoW | Liraglutide, Placebo | Biolingus, Chinese University of Hong Kong | Diabete Type 2 | 05/24 | 07/24 | | |
NCT04441216: Effects of TCM on Beta-cell Function and Insulin Resistance in High Risk Chinese Individuals for T2D (TCM_PDiab_P01) |
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| Recruiting | N/A | 40 | RoW | Rhizoma Coptidis, Radix Astragali and Flos Lonicerae, Rhizoma Coptidis, Radix Astragali and Flos Lonicerae, Ophiopogonis Radix | Chinese University of Hong Kong | Prediabetic State | 06/23 | 06/23 | | |
| Not yet recruiting | N/A | 9000 | RoW | Risk assessment with biogenetic and clinical test to predict diabetes risk, Oral glucose tolerance test (OGTT) and cardiovascular-kidney-metabolic (CKM) risk factors, Medication, Continuous glucose monitoring (CGM) devices and/or weighing scale, Visit to family doctor with nurse education, Joint Asia Diabetes Evaluation (JADE) assessment, Education webinars, workshops and health messages | Juliana CN Chan, Chinese University of Hong Kong, St James' Settlement, Asia Diabetes Foundation | Diabetes, Pre Diabetes, Hypertension, Dyslipidemia, Obesity | 10/27 | 05/28 | | |
NCT04049149: Precision Medicine in Chinese Patients With Young Onset Diabetes |
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| Active, not recruiting | N/A | 884 | RoW | Biogenetic explanation and endocrinologist intensive managment, Usual care management | Chinese University of Hong Kong | Type 2 Diabetes | 12/24 | 12/24 | | |
| Chan, Gary M |
NCT03356652: Electrical Activation Mapping Guided Tailor Made Approach for Cardiac Resynchronization Therapy |
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| Recruiting | N/A | 93 | RoW | Noninvasive electrical dyssynchrony study, Noninvasive electrical activation, Electrical Activation Mapping, Noninvasive mapping system, ECVUE | Chinese University of Hong Kong | Heart Failure | 08/24 | 08/24 | | |
| Lai, Ching Lung |
NCT03546829: Safety Trial of Antimicrobial Therapy and Precision Radiation Therapy in Patients With Oligoprogressive Non-small Cell Lung Cancer |
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| Recruiting | 1 | 10 | US | Vancomycin, Precision hypofractionated radiation | Abramson Cancer Center at Penn Medicine | Early Stage Non-Small Cell Lung Cancer | 12/26 | 12/27 | | |
NCT04598438: Music to Enhance Auditory Encoding in Young Children |
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| Recruiting | N/A | 48 | RoW | Music behavioral early intervention program, Arts and crafts early enhancement program | Chinese University of Hong Kong | Healthy | 10/22 | 03/25 | | |
NCT06318338: Virtual Reality to Promote Relaxation Prior to Simulation |
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| Recruiting | N/A | 25 | US | Virtual Reality Program | Abramson Cancer Center at Penn Medicine | Cancer | 03/25 | 03/25 | | |
| Wong, Wing Hang |
NCT06126185: Open-label Pilot Study Synbiotic Treatment for Autism Spectrum Disorder |
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| Recruiting | N/A | 30 | RoW | 12-week course of synbiotic | Chinese University of Hong Kong | Autism Spectrum Disorder, Anxiety | 12/24 | 07/25 | | |
NCT05927207: Pilot Testing of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD) |
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| Completed | N/A | 30 | RoW | TRIP | Chinese University of Hong Kong | Autism Spectrum Disorder, Parent-Child Relations | 08/24 | 08/24 | | |
NCT05927116: RCT of a Mobile Phone App-based Intervention for Parents of Children With Autism Spectrum Disorder (ASD) |
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| Recruiting | N/A | 700 | RoW | Mobile phone app-based intervention for supporting and empowering parents of children with autism spectrum disorder (ASD), TRIP app for ASD parents | Chinese University of Hong Kong | Autism Spectrum Disorder, Parent-Child Relations | 04/26 | 07/26 | | |
| Yeung, Yat Wah |
| Recruiting | N/A | 400 | RoW | | Chinese University of Hong Kong | Abnormalities Uterine, Vaginal Abnormality | 02/25 | 02/25 | | |
| Li, Jing |
BRAVO, NCT05647915: Effects of Berberine in Reducing Abdominal Visceral Adipose Tissue Among Individuals with Obesity and NAFLD |
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| Completed | 4 | 337 | RoW | Berberine plus lifestyle intervention, Placebo plus lifestyle intervention | China National Center for Cardiovascular Diseases | Obesity, Obesity, Abdominal, NAFLD | 08/24 | 08/24 | | |
NCT06425120: Effect of Xuesaitong Soft Capsules on Major Risk Factors in Patients With Coronary Heart Disease |
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| Not yet recruiting | 4 | 240 | RoW | Xuesaitong Soft Capsule, LixuwangⓇ, Placebo | China National Center for Cardiovascular Diseases | Coronary Heart Disease | 12/24 | 12/24 | | |
NCT04624854: Dual Anti-Platelet Therapy in Patients With Coronary Multi-Vessel Disease (DAPT-MVD) |
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| Active, not recruiting | 4 | 8250 | RoW | Clopidogrel and Aspirin dual-antiplatelet therapy, Aspirin monotherapy | Harbin Medical University, Chinese Society of Cardiology, Lepu Medical Technology (Beijing) Co., Ltd. | Coronary Artery Disease, Myocardial Ischemia, Acute Coronary Syndrome, Heart Diseases, Syndrome Heart Disease, Cardiovascular Diseases, Arteriosclerosis, Arterial Occlusive Diseases, Coronary Disease, Vascular Diseases | 04/25 | 04/25 | | |
NCT05965284: Efficacy and Safety for Telitacicept in the Remission Maintenance Treatment of ANCA-associated Vasculitis (TTCAZAREM) |
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| Recruiting | 4 | 40 | RoW | Azathioprine, Telitacicept, Taiai for commercial name | Chinese SLE Treatment And Research Group | ANCA-associated Vasculitis, Maintenance Therapy | 12/25 | 12/26 | | |
ABCD, NCT05749874: Effects of Berberine on Preventing Cardiovascular Disease and Diabetes Mellitus |
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| Not yet recruiting | 4 | 6500 | RoW | Berberine plus lifestyle intervention, Placebo plus lifestyle intervention | China National Center for Cardiovascular Diseases | PreDiabetes, Abdominal Obesity, Hypertension, Dyslipidemias | 12/26 | 12/26 | | |
NCT05962840: Efficacy and Safety for Rituximab Combined With Telitacicept in the Treatment of ANCA-associated Vasculitis (TTCAAVREM) |
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| Recruiting | 4 | 40 | RoW | Telitacicept, Taiai for commercial name, Placebo of Telitacicept | Chinese SLE Treatment And Research Group, Peking Union Medical College Hospital | ANCA Associated Vasculitis | 12/26 | 12/26 | | |
EHTASEOCCS, NCT03373058: Efficacy of HIPEC in the Treatment of Advanced-Stage Epithelial Ovarian Cancer After Cytoreductive Surgery |
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| Recruiting | 3 | 310 | RoW | Hyperthermic Intraperitoneal Chemotherapy, HIPEC, cytoreductive surgery, CRS, adjuvant chemotherapy, ACT | Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, Third Affiliated Hospital, Sun Yat-Sen University, Henan Provincial People's Hospital, Xiangya Hospital of Central South University, The Third Xiangya Hospital of Central South University, Peking University Cancer Hospital & Institute, Peking University People's Hospital, Cancer Hospital of Guizhou Province, Chinese PLA General Hospital, Hebei Medical University Fourth Hospital, The Second Hospital of Hebei Medical University, West China Second University Hospital, Peking Union Medical College Hospital, First Affiliated Hospital, Sun Yat-Sen University, Henan Cancer Hospital, Tianjin Medical University Cancer Institute and Hospital, The Third Affiliated Hospital of Guangzhou Medical University, Wuhan University, RenJi Hospital, Obstetrics & Gynecology Hospital of Fudan University, Southern Medical University, China, Fourth Affiliated Hospital of Guangxi Medical University, Shandong Cancer Hospital and Institute, Beijing Obstetrics and Gynecology Hospital, Chongqing University Cancer Hospital, Xinqiao Hospital of Chongqing, Wuhan Union Hospital, China, First Affiliated Hospital of Chongqing Medical University, Affiliated Cancer Hospital of Shantou University Medical College | Epithelial Ovarian Cancer, Fallopian Tube Cancer, Primary Peritoneal Carcinoma | 07/21 | 07/23 | | |
| Terminated | 3 | 372 | Europe, US, RoW | Pamrevlumab, FG-3019, Placebo | FibroGen | Idiopathic Pulmonary Fibrosis | 09/23 | 09/23 | | |
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| Active, not recruiting | 3 | 404 | Europe, Canada, Japan, US, RoW | Atrasentan, CHK-01, Atrasentan Hydrochloride, ABT-627, Placebo | Chinook Therapeutics, Inc. | IgA Nephropathy, Immunoglobulin A Nephropathy | 12/26 | 12/26 | | |
SHINY, NCT06157502: Shuxuening Injection in the Treatment With Intravenous Thrombolysis in Patients With Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Shuxuening Injection, Placebo | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 06/25 | 12/26 | | |
TAPIS, NCT06316570: Ticagrelor With Aspirin Dual Antiplatelet Therapy Combined With Intravenous Thrombolysis for Ischemic Stroke |
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| Recruiting | 3 | 1380 | RoW | Early Dual Antiplatelet Therapy, Ticagrelor and Aspirin, Placebo, Placebo of Ticagrelor and Aspirin | Beijing Tiantan Hospital | Ischemic Stroke, Acute | 12/25 | 12/26 | | |
Be-CLEVER, NCT05976152: Effect of Butyphthalide on Cognitive Level Change After Cerebral Vascular Event-a Randomized Control Trial |
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| Recruiting | 3 | 3200 | RoW | dl-3-butylphthalide, DL-3-n-butylphthalide (NBP), dl-3-butylphthalide placebo, NBP placebo | Fudan University | Stroke, Post-stroke Cognitive Impairment (PSCI) | 12/26 | 12/26 | | |
NCT01592968: Stereotactic Radiosurgery or Whole Brain Radiation Therapy in Treating Patients With Newly Diagnosed Non-melanoma Brain Metastases |
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| Active, not recruiting | 3 | 88 | US | Cognitive Assessment, Quality-of-Life Assessment, Quality of Life Assessment, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Whole-Brain Radiotherapy, WBRT, whole-brain radiation therapy | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Metastatic Malignant Neoplasm, Metastatic Malignant Neoplasm in the Brain | 09/25 | 09/25 | | |
NHIPEC, NCT05246020: Efficacy of Neoadjuvant Hyperthermic Intraperitoneal Chemotherapy in Advanced High-grade Serous Ovarian Cancer (the Trial) |
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| Recruiting | 2 | 80 | RoW | HIPEC, intravenous chemotherapy | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Hyperthermic Intraperitoneal Chemotherapy, Neoadjuvant Chemotherapy | 12/22 | 12/24 | | |
NCT02713269: Thermal Ablation and Spine Stereotactic Radiosurgery in Treating Patients with Spine Metastases At Risk for Compressing the Spinal Cord |
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| Active, not recruiting | 2 | 60 | US | Computed Tomography, CAT, CAT Scan, Computerized Axial Tomography, computerized tomography, CT, CT SCAN, tomography, Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery, Thermal Ablation Therapy, thermal ablation | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Malignant Digestive System Neoplasm, Metastatic Head and Neck Carcinoma, Metastatic Kidney Carcinoma, Metastatic Malignant Neoplasm in the Spine, Metastatic Malignant Neoplasm of Unknown Primary, Metastatic Melanoma, Prostate Carcinoma Metastatic in the Bone, Sarcoma, Solid Neoplasm, Spinal Cord Compression, Stage IV Breast Cancer AJCC V6 and V7, Stage IV Lung Non-Small Cell Cancer AJCC V7, Thyroid Gland Carcinoma | 08/25 | 08/25 | | |
NCT06205927: Randomized Study of Carbon Ion Boost in Hypoxic Lesions for Locally Advanced Non-small Cell Lung Cancer |
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| Recruiting | 2 | 77 | RoW | Standard carbon ion beam radiotherapy, Carbon ion beam radiotherapy simultaneously dose boost | Jian Chen | Non-small Cell Lung Cancer | 12/24 | 12/26 | | |
NCT06206278: Evaluation of Infigratinib in Patients With Locally Advanced or Metastatic Gastric Cancer or GEJ Adenocarcinoma |
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| Terminated | 2 | 6 | RoW | Infigratinib, BGJ398, BBP-831 | LianBio LLC | Gastric Cancer, Gastroesophageal Junction Adenocarcinoma | 05/24 | 05/24 | | |
NCT06186726: Clinical Study of Carbon Ion Radiotherapy Combined With Chemotherapy for Thymic Epithelial Tumors |
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| Recruiting | 2 | 48 | RoW | carbon ion radiotherapy | Jian Chen | Carbon Ion Radiotherapy, Thymoma, Thymic Carcinoma, Radiotherapy, Chemotherapy | 12/26 | 12/29 | | |
NCT06311981: Carbon Ion Radiotherapy for Locally Advanced Lung Cancer in Elderly Patients |
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| Recruiting | 2 | 29 | RoW | carbon ion radiotherapy, targeted therapy, single regimen chemotherapy in sequence with radiotherapy | Jian Chen | Non-small Cell Lung Cancer, Older People, Carbon Ion Radiotherapy, Radiotherapy Side Effect | 06/25 | 06/26 | | |
NCT06311955: Clinical Study of Postoperative Carbon Ion Radiotherapy for Thymus Tumor With Residual Tumor |
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| Recruiting | 2 | 48 | RoW | Carbon ion radiotherapy, combined with platinum-based regimen | Jian Chen | Thymic Epithelial Tumor, Radiotherapy Side Effect, Carbon Ion Radiotheray, Heavy Ion Radiotherapy | 02/28 | 02/29 | | |
NCT06311968: The Clinical Study of Post-operative Proton Radiotherapy for Thymus Tumor |
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| Recruiting | 2 | 55 | RoW | Proton radiotherapy, combined platinum based chemotherapy | Jian Chen | Thymus Epithelial Tumor, Proton Radiotherapy, Radiation Toxicity | 02/27 | 02/27 | | |
| Not yet recruiting | 2 | 120 | RoW | Metformin Hydrochloride tablet, Metformin, Placebo | Xuanwu Hospital, Beijing, Institute of Zoology, Chinese Academy of Sciences, Beijing Institute of Genomics, Chinese Academy of Sciences, Merck Serono Co., Ltd., China | Metformin, Aging | 09/26 | 07/28 | | |
| Active, not recruiting | 2 | 49 | US | Quality-of-Life Assessment, Quality of Life Assessment, Questionnaire Administration, Stereotactic Radiosurgery, Stereotactic External Beam Irradiation, stereotactic external-beam radiation therapy, stereotactic radiation therapy, Stereotactic Radiotherapy, stereotaxic radiation therapy, stereotaxic radiosurgery | M.D. Anderson Cancer Center, National Cancer Institute (NCI) | Clinical Stage IV Cutaneous Melanoma AJCC V8, Metastatic Malignant Neoplasm in the Brain, Metastatic Melanoma, Pathologic Stage IV Cutaneous Melanoma AJCC V8 | 08/26 | 08/26 | | |
