Chan, Piu |
NCT06147713: Vibrotactile Foot Device for Freezing of Gait in Parkinson's Disease |
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| Recruiting | N/A | 200 | RoW | Vibrotactile foot device (Smart shoe) | Xuanwu Hospital, Beijing | Parkinson Disease, Freezing of Gait | 11/24 | 11/24 | | |
Zhang, Yan |
NCT05291650: Ultrasound-guided Injection of Glucocorticoid Into Infrapatellar Fat Pad in Patients With Knee Osteoarthritis |
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| Completed | 4 | 60 | RoW | Glucocorticoids, Saline, Hyaluronic acid | Zhujiang Hospital | Osteoarthritis, Knee | 09/23 | 12/23 | | |
NCT04790305: Effect of Huaier Granule on Adjuvant Treatment for High-risk Early-stage Triple-negative Breast Cancer |
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| Recruiting | 4 | 1072 | RoW | Huaier Granule, Z20000109(NMPA Approval Number) | Fudan University, LinkDoc Technology (Beijing) Co. Ltd., Huazhong University of Science and Technology | Carcinoma Breast, Triple-negative Breast Cancer, Invasive Ductal Carcinoma, Breast | 12/27 | 07/28 | | |
ETER701, NCT04234607: A Study of TQB2450 or Placebo Combined With Anlotinib, Etoposide and Carboplatin Versus Etoposide and Carboplatin in Subjects With Extensive Small Cell Lung Cancer |
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| Not yet recruiting | 3 | 738 | RoW | TQB2450, Anlotinib, Etoposide, Carboplatin, TQB2450(blank), Anlotinib(blank) | Chia Tai Tianqing Pharmaceutical Group Co., Ltd. | Extensive Small Cell Lung Cancer | 12/22 | 12/22 | | |
| Active, not recruiting | 3 | 453 | Europe, US, RoW | MRTX849, adagrasib, KRAZATI, Docetaxel, Taxotere | Mirati Therapeutics Inc., Mirati Therapeutics, Inc. | Metastatic Non Small Cell Lung Cancer, Advanced Non Small Cell Lung Cancer | 12/23 | 12/24 | | |
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NCT05181137 / 2021-001940-86: A Phase 3 Study to Investigate the Efficacy and Safety of SHR0302 With Moderately to Severely Active Ulcerative Colitis |
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| Recruiting | 3 | 368 | Europe, US, RoW | SHR0302, Placebo | Reistone Biopharma Company Limited, Reistone Biopharma Company Limited | Ulcerative Colitis | 10/24 | 03/25 | | |
SUNRAY-01, NCT06119581: A Study of First-Line Olomorasib (LY3537982) and Pembrolizumab With or Without Chemotherapy in Patients With Advanced KRAS G12C-Mutant Non-small Cell Lung Cancer |
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| Recruiting | 3 | 1016 | Europe, Canada, Japan, US, RoW | LY3537982, Olomorasib, Pembrolizumab, Placebo, Cisplatin, Carboplatin, Pemetrexed | Eli Lilly and Company, Loxo Oncology, Inc. | Carcinoma, Non-Small-Cell Lung, Neoplasm Metastasis | 10/26 | 10/29 | | |
NCT02159820: Lower Dose Decitabine (DAC)-Primed TC (Carboplatin-Paclitaxel) Regimen in Ovary Cancer |
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| Recruiting | 2/3 | 500 | RoW | Decitabine (DTC Arm), Paclitaxel and Carboplatin (TC Arm) | Chinese PLA General Hospital | Primary Malignant Neoplasm of Ovary, FIGO Stages II to IV | 06/24 | 06/24 | | |
EVEREST, NCT06531161: EleVation carE: a Randomized Controlled Trial on the Prevention of Acute Mountain Sickness With Suxiao Jiuxin Pill |
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| Not yet recruiting | 2/3 | 168 | NA | Suxiao Jiuxin Pill, Placebo | Peking University First Hospital, Tibet Autonomous Region Hospital of Traditional Tibetan Medicine | Acute Mountain Sickness | 09/24 | 09/25 | | |
NCT03989336: A Study of the Pan-immunotherapy in Patients With Relapsed/Refractory Ovarian Cancer |
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| Completed | 2 | 84 | RoW | Manganese Chloride, nab-paclitaxel, Paclitaxel For Injection (Albumin Bound), Platinum chemotherapy, Sintilimab, anti-PD-1 antibody; PD-1 inhibitor | Chinese PLA General Hospital | Ovarian Cancer | 05/22 | 12/23 | | |
NCT03250962: SHR-1210 Alone or in Combination With Decitabine in Relapsed or Refractory Hodgkin Lymphoma |
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| Recruiting | 2 | 280 | RoW | SHR-1210, Decitabine | Chinese PLA General Hospital | Hodgkin Lymphoma | 07/22 | 03/25 | | |
LEAD, NCT05092412: Low-dose Radiotherapy Combined With Durvalumab, Chemotherapy(EP) in the Treatment of ES-SCLC |
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| Active, not recruiting | 2 | 30 | RoW | Low-dose radiotherapy, Durvalumab, Etoposide, and cisplatin/carboplatin | You Lu, AstraZeneca | Lung Cancer, Extensive-stage Small-cell Lung Cancer, Durvalumab | 02/23 | 06/25 | | |
| Recruiting | 2 | 30 | RoW | Polatuzumab Vedotin, Rituximab, Lenalidomide | Yan Zhang, MD, Peking University Third Hospital, Peking University First Hospital, Chinese PLA General Hospital | Diffuse Large B Cell Lymphoma | 10/25 | 10/27 | | |
PUMCH-NHL-013, NCT05390749: Sequential Treatment With RO-MTX After Pomalidomide, Orelabrutinib, Rituximab (POR) in Newly-diagnosed PCNSL |
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| Recruiting | 2 | 50 | RoW | Orelabrutinib, Pomalidomide, Rituximab, Methotrexate | Peking Union Medical College Hospital, Beijing Tiantan Hospital, Sanbo Brain Hospital Capital Medical University | Primary Central Nervous System Lymphoma | 04/24 | 04/26 | | |
NCT06632262: A Phase 2 Clinical Study of ABSK061 and ABSK043 |
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| Not yet recruiting | 2 | 202 | RoW | ABSK061 + ABSK043, ABSK061+ABSK043 in combination with CAPOX | Abbisko Therapeutics Co, Ltd | HER2-Gastric/Gastroesophageal Junction Cancer, Urothelial Carcinoma, Non-Small Cell Lung Cancer, Solid Tumors | 11/29 | 06/30 | | |
FOCUS-C, NCT05334277: Furmonertinib Monotherapy and Combination Therapy in Advanced EGFR Mutant NSCLC With Uncleared ctDNA |
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| Recruiting | 2 | 280 | RoW | Furmonertinib, AST2818, Furmonertinib/Pemetrexed/Carboplatin, Furmonertinib/Pemetrexed/Carboplatin/Bevacizumab | Sun Yat-sen University, Allist Pharmaceuticals, Inc., GeneCast Biotechnology Co., Ltd. | Non-small Cell Lung Cancer | 02/25 | 02/28 | | |
IMM01-04, NCT05833984: Safety and Efficacy of IMM01 Plus Tislelizumab in Patients With Advanced Solid Tumors and Lymphomas |
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| Recruiting | 1b/2 | 309 | RoW | IMM01, SIRPα Fc, Tislelizumab | ImmuneOnco Biopharmaceuticals (Shanghai) Inc. | Solid Tumor, Classic Hodgkin Lymphoma | 02/24 | 11/24 | | |
NCT03989310: An Open-label, Phase I/II Study of the Pan-immunotherapy in Patients With Local Advanced/Metastatic Pancreatic Cancer |
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| Recruiting | 1/2 | 50 | RoW | Manganese Chloride, nab-paclitaxel, Paclitaxel For Injection (Albumin Bound), Gemcitabine, anti-PD-1 antibody, Anti-PD-1 monoclonal antibody; PD-1 inhibitor | Chinese PLA General Hospital | Pancreatic Cancer | 05/21 | 03/22 | | |
NCT04588324: Study of SHR2150 (TLR7 Agonist) in Combination With Chemotherapy Plus PD-1 or CD47 Antibody in Subjects With Unresectable/ Metastatic Solid Tumors |
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| Recruiting | 1/2 | 50 | RoW | SHR2150, Anti-Cancer Agent | Chinese PLA General Hospital | Solid Tumor | 11/21 | 11/22 | | |
NCT04873440: An Open-label, Phase I/II Study of Manganese Plus Radiotherapy in Patients With Metastatic Solid Tumors or Lymphoma |
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| Recruiting | 1/2 | 10 | RoW | Manganese Chloride, Mn2+, Radiotherapy, Chemo-immunotherapy | Chinese PLA General Hospital | Solid Tumor, Lymphoma | 05/22 | 05/23 | | |
REMLA, NCT04120350: R2-MTX With Lenalidomide Maintenance in Newly-diagnosed PCNSL:a Multicenter Phase Ib/II Stuty |
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| Recruiting | 1/2 | 47 | RoW | Methotrexate, Rituximab, Lenalidomide | Peking Union Medical College Hospital, Beijing Tiantan Hospital, Xuanwu Hospital, Beijing, Peking University Third Hospital, Beijing Hospital, Peking University First Hospital, Chinese PLA General Hospital | Primary Central Nervous System Lymphoma | 08/22 | 08/24 | | |
NCT05867771: A Study of PM1022 in Patients With Advanced Tumors |
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| Recruiting | 1/2 | 200 | RoW | PM1022 | Biotheus Inc. | Advanced Tumors | 04/24 | 04/25 | | |
NCT05416775: Phase Ib/II Study of SHR-8068 Injection in the Treatment of Advanced Non-small Cell Lung Cancer |
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| Recruiting | 1/2 | 168 | RoW | SHR-8068;Adebrelimab, SHR-8068;adebrelimab and platinum-based chemotherapy, Adebrelimab;platinum-based chemotherapy | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Non-small Cell Lung Cancer | 06/26 | 06/26 | | |
NCT05245916: IBI397 or Combination Therapies in Patients With Advanced Malignancies |
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| Withdrawn | 1a/1b | 30 | RoW | IBI397, IBI397+Sintilimab, IBI397+Rituximab | Innovent Biologics (Suzhou) Co. Ltd. | Advanced Malignancies | 08/23 | 08/23 | | |
NCT06271928: A Multicenter Clinical Study of Yijing Keli in the Treatment of Ovarian Aging |
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| Recruiting | 1 | 100 | RoW | Yijing Keli | Tongji Hospital | Ovarian Aging | 01/24 | 01/25 | | |
NCT04487093: Clinical Study of Neoantigen Vaccine Combined With Targeted Drugs in the Treatment of Non-small Cell Lung Cancer |
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| Recruiting | 1 | 20 | RoW | neoantigen vaccine + EGFR-TKI, neoantigen vaccine + anti-angioge | First Hospital of Shijiazhuang City, Tianjin Hengjia Biotechnology Development co., LTD | Non Small Cell Lung Cancer | 05/22 | 12/22 | | |
NCT06256783: A Clinical Study of Baozhu Keli in the Treatment of Ovarian Aging |
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| Recruiting | 1 | 100 | RoW | Baozhu Keli | Tongji Hospital | Ovarian Aging | 01/24 | 01/25 | | |
| Recruiting | 1 | 132 | Japan, RoW | SHR-A2009 | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Solid Tumors | 12/23 | 12/24 | | |
NCT05508334: A Study to Assess the Safety and Tolerability of RC88 for Patients with Advanced Solid Tumours |
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| Active, not recruiting | 1 | 81 | RoW | RC88, The injectable RC88 | RemeGen Co., Ltd. | Advanced Solid Tumours | 06/25 | 12/25 | | |
| Recruiting | 1 | 156 | US, RoW | CS5001 | CStone Pharmaceuticals | Advanced Solid Tumor, Advanced Lymphoma | 03/25 | 06/25 | | |
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NCT06384352: A Phase I Study to Evaluate the Safety,Tolerability, Pharmacokinetics, and Efficacy of YL211 in Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 155 | Canada, US, RoW | YL211 | MediLink Therapeutics (Suzhou) Co., Ltd., Hoffmann-La Roche | Advanced Solid Tumors | 04/27 | 04/29 | | |
| Completed | N/A | 70 | RoW | Plasma exchange (PE), intravenous immunmoglobulin (IVIG), intravenous methylprednisolone (IVMP) | Xuanwu Hospital, Beijing | Autoimmune Encephalitis | 12/22 | 09/24 | | |
NCT03703284: Molecular Mechanisms of Malignant Cerebral Edema After LHI |
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| Recruiting | N/A | 120 | RoW | Treatments to reduce intracranial pressure | Xuanwu Hospital, Beijing | Cerebral Edema | 12/22 | 06/23 | | |
UltraFuture I, NCT05498740: Post-marketing Study in Femoral Popliteal Artery of Drug Coated Balloon Used for Treatment of Lower Limb Ischemia |
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| Recruiting | N/A | 200 | RoW | Drug eluting Balloon | Zhejiang Zylox Medical Device Co., Ltd. | Peripheral Arterial Disease (PAD) | 12/22 | 12/24 | | |
NCT05447572: FIT Combining FC for Predicting MH and Histology Remission in UC |
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| Recruiting | N/A | 300 | RoW | FIT + FC | Shandong University | Ulcerative Colitis, Histology Remission, Fecal Calprotetin, FIT, Mucosal Healing | 12/22 | 12/23 | | |
NCT04361357: The Effects of Enteral Whey Protein Supplement on Serum Albumin Level in Acute Critically Ill Neurological Patients |
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| Recruiting | N/A | 116 | RoW | whey protein | Xuanwu Hospital, Beijing | Nutrition Disorders, Neurologic Disorder | 12/22 | 12/22 | | |
NCT05840861: Using 18F-FPEB PET to Identify mGLUR5 Availability in Affective Disorders |
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| Recruiting | N/A | 59 | RoW | Vortioxetine, Quetiapine | Central South University | Major Depressive Disorder, Bipolar Disorder | 08/23 | 09/23 | | |
DELTA, NCT05608655: DKutting Balloon Versus Chocolate Balloon to Treat Femoral and Popliteal Artery Stenosis |
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| Completed | N/A | 188 | RoW | DKutting LL balloon, Chocolate balloon | DK Medical Technology (Suzhou) Co., Ltd. | Femoral Artery Stenosis, Popliteal Artery Stenosis | 01/24 | 02/24 | | |
BIATICH, NCT05593380: The Effect of BIA Monitoring of Brain Edema on the Neurological Prognosis of Supratentorial Massive ICH |
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| Recruiting | N/A | 190 | RoW | Parenchymal Intracranial pressure monitor, Integra Life Sciences Camino Intracranial Monitor, Treatment based on clinical and imaging observations | Xiangya Hospital of Central South University | Cerebral Hemorrhage, Hypertensive, Intracranial Hypertension, Monitoring, Critical Care, Treatment Outcome, Invasive Intracranial Pressure Monitoring, Large-volume Cerebral Hemorrhage | 12/24 | 03/25 | | |
NCT06130319: Correlation of Disease Management and Quality of Life in Patients With Chronic Heart Failure and Their Family Caregivers |
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| Recruiting | N/A | 278 | RoW | | Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University | Chronic Heart Failure | 06/24 | 06/24 | | |
| Not yet recruiting | N/A | 768 | RoW | early pancreatic stent placement (EPSP), late pancreatic stent placement (EPSP) | The First Affiliated Hospital of Anhui Medical University, First Affiliated Hospital Bengbu Medical College, Anqing Municipal Hospital, First Affiliated Hospital of Wannan Medical College, Tongcheng People's Hospital of Anhui province, Fuyang people's hospital | Cholangiopancreatography, Endoscopic Rretrograde, Post-ERCP Pancreatitis | 03/26 | 03/26 | | |
NCT06452173: Risk Prediction Model for Cerebrovascular Events in Carotid Artery Stenosis |
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| Enrolling by invitation | N/A | 300 | RoW | Plasma, carotid high-resolution magnetic resonance imaging | Beijing Tiantan Hospital, Beijing Neurosurgical Institute | Carotid Stenosis | 10/26 | 12/26 | | |
NCT06606509: The Survey of Treatment and Metabolic Status of Type 1 Diabetes Mellitus (T1DM). |
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| Not yet recruiting | N/A | 1000 | RoW | Continuous Glucose Monitoring System (GX-01S) | Nanjing First Hospital, Nanjing Medical University | Type1 Diabetes Mellitus | 10/26 | 06/27 | | |
NCT05454397: A Study on the Status of Nutritional Risk Screening and Nutritional Therapy in Neurology Hospitalized Stroke Patients |
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| Recruiting | N/A | 2000 | RoW | Observational study, no intervention | Nanfang Hospital of Southern Medical University, First Affiliated Hospital of Fujian Medical University, Yantai Yuhuangding Hospital, The First Hospital of Jilin University, Qilu Hospital of Shandong University, ZHEJIANG PROVINCE XIAOSHAN HOSPITAL, The First People's Hospital of Wenling, Ganzhou People's Hospital, Affiliated Hospital of Jining Medical hospital, Henan Provincial People's Hospital, Zhongda Hospital Southeast University, The Second Affiliated Hospital of Harbin Medical University, The First people's Hospital of Kunshan, The 2nd Affiliated Hospital of Wenzhou Medical University, THE FIRST PEOPLE'S HOSPITAL OF JIASHAN, The First Affiliated Hospital of Xi'an Jiaotong University Medical College, Fujian Province Zhangzhou Hospital, People's Hospital of Chongqing, Nanjing Zijin Hospital, Hangzhou Red Cross Hospital, Wenzhou Hospital of Chinese Medicine, Kaifeng Central Hospital, First Affiliated Hospital of Guangxi Medical University, Zhongshan Hospital of Xiamen University, Xi'an Encephalopathy of Traditional Chinese Medicine Hospital, 903 Hospital of the Chinese People's Liberation Army Joint Logistics and Security Forces, Xiangya Hospital of Central South University, Second Affiliated Hospital of Suzhou University, Tongji Hospital, The Affiliated Hospital o fQingdao University, The First Affiliated Hospital of Anhui Medical University, Yancheng Third People's Hospital, Linyi People's Hospital, Dongfang Hospital of Beijing University of Chinese Medicine, Affiliated Hospital of Qingdao University | Acute Stroke | 10/22 | 10/23 | | |
Ji, Xunming |
NCT05965687: Normobaric Hyperoxia Combined With Intravenous Thrombolysis for Acute Ischemic Stroke (OPENS-3) |
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| Recruiting | 3 | 1230 | RoW | Normobaric Hyperoxia, Nasal oxygen, Intravenous thrombolysis(rt-PA) | Ji Xunming,MD,PhD, Beijing Friendship Hospital, Beijing Shijitan Hospital, Capital Medical University, Beijing Tongren Hospital, People's Hospital of Beijing Daxing District, Tianjin Huanhu Hospital, Guizhou Provincial People's Hospital, Shandong Provincial Hospital, The First Affiliated Hospital of Soochow University, The First Affiliated Hospital of Zhengzhou University, The Affiliated Hospital of Xuzhou Medical University, Jining First People's Hospital, Linyi People's Hospital, Nanyang Central Hospital, Rizhao People's Hospital, Zhumadian Central Hospital, Second Affiliated Hospital of Nanchang University, Affiliated Hospital of Nantong University, The Second Hospital of Anhui Medical University, Changsha Central Hospital, Jiujiang University Affiliated Hospital, Liaocheng People's Hospital, Chengde Central Hospital, The First Affiliated Hospital of Anhui Medical University, Jiangxi Provincial People's Hopital | Acute Ischemic Stroke | 08/24 | 10/24 | | |
RECAST-MT, NCT06559241: Remote Ischemic Conditioning for Acute Ischemic Stroke Treated with Mechanical Thrombectomy() |
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| Recruiting | 3 | 2105 | RoW | 14-day remote ischemic conditioning, 14-day RIC, 30-day remote ischemic conditioning, 30-day RIC, Endovascular thrombectomy, EVT, Best medical management | Capital Medical University | Acute Ischemic Stroke, Anterior Circulation Brain Infarction | 11/26 | 02/27 | | |
NCT05965193: Normobaric Hyperoxia Combined With Intravenous Thrombolysis for Acute Ischemic Stroke:Longterm Outcome (OPENS-3L) |
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| Recruiting | 3 | 1230 | RoW | Normobaric Hyperoxia, Nasal oxygen, Intravenous thrombolysis(rt-PA) | Ji Xunming,MD,PhD, Beijing Friendship Hospital, Beijing Shijitan Hospital, Capital Medical University, Beijing Tongren Hospital, People's Hospital of Beijing Daxing District, Tianjin Huanhu Hospital, Guizhou Provincial People's Hospital, Shandong Provincial Hospital, The First Affiliated Hospital of Soochow University, The First Affiliated Hospital of Zhengzhou University, The Affiliated Hospital of Xuzhou Medical University, Jining First People's Hospital, Linyi People's Hospital, Nanyang Central Hospital, Rizhao People's Hospital, Zhumadian Central Hospital, Second Affiliated Hospital of Nanchang University, Affiliated Hospital of Nantong University, The Second Hospital of Anhui Medical University, Changsha Central Hospital | Acute Ischemic Stroke | 08/25 | 10/25 | | |
| Recruiting | 2/3 | 98 | RoW | Statin | Capital Medical University | Intracerebral Hemorrhage, Statins | 06/24 | 11/24 | | |
IRIS, NCT06238024: Effect of Interleukin-6 Receptor Inhibition in Patients With Ischemic Stroke Undergoing Endovascular Treatment |
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| Completed | 2/3 | 108 | RoW | Tocilizumab, NaCl 0.9% 100ml | Suzhou Municipal Hospital of Anhui Province, Xuanwu Hospital, Beijing | Interleukin-6, Ischemic Stroke, Endovascular Treatment | 06/24 | 09/24 | | |
| Recruiting | 2 | 100 | RoW | NBO | Capital Medical University | Acute Stroke, Ischemic Stroke, Acute | 07/22 | 10/22 | | |
| Completed | 2 | 282 | RoW | Normobaric Hyperoxia, NBO, Sham Normobaric Hyperoxia, Sham NBO, Endovascular Thrombectomy, EVT | Capital Medical University, Tianjin Huanhu Hospital, Shengli Oilfield Hospital, Beijing Fengtai You'anmen Hospital, Jiujiang University Affiliated Hospital, Zhangzhou Municipal Hospital of Fujian Province, Baotou Central Hospital, Luoyang Central Hospital, Nanyang Central Hospital, Qingdao Central Hospital, The Third People's Hospital of Jinan, Rizhao People's Hospital, Anyang People's Hospital, Shanghai 10th People's Hospital, Dalian Municipal Central Hospital, Zhoukou Central Hospital, Nanshi Hospital of Nanyang, The second Nanning People's Hospital, Zhumadian Central Hospital, Taizhou Hospital, Second Affiliated Hospital of Nanchang University | Stroke, Acute, Neuroprotection | 05/23 | 05/23 | | |
| Recruiting | 1 | 32 | RoW | chlorpromazine and promethazine, C+P, lytic cocktail, Placebo group, Control group, endovascular thrombectomy, rt-PA, Intravenous thrombolysis | Capital Medical University, Linyi People's Hospital | Acute Ischemic Stroke | 01/25 | 02/25 | | |
RE-HIBER, NCT04554797: Regional Hypothermia in Combination With Endovascular Thrombectomy in Acute Ischemic Stroke |
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| Recruiting | N/A | 60 | RoW | Regional Hypothermia | Capital Medical University | Stroke, Neuroprotection, Hypothermia | 12/20 | 03/21 | | |
RIC-PMD, NCT03546309: Safety and Efficacy of RIC in Pediatric Moyamoya Disease Patients Treated With Revascularization Therapy |
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| Recruiting | N/A | 42 | RoW | RIC group, Medication group | Capital Medical University, The Fifth Medical Center of the Chinese People's Liberation Army (PLA) General Hospital | Moyamoya Disease, Pediatric | 12/24 | 02/25 | | |
| Not yet recruiting | N/A | 40 | NA | remote ischemic conditioning | Capital Medical University | 2,3-Bisphosphoglycerate | 03/21 | 03/21 | | |
NCT02737189: Basilar Artery Occlusion Chinese Endovascular Trial |
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| Completed | N/A | 217 | RoW | Mechanical embolectomy, Medical Treatment | Xuanwu Hospital, Beijing, Zhangzhou Municipal Hospital of Fujian Province, The First People's Hospital of Changzhou, Xinqiao Hospital of Chongqing, Changhai Hospital, Baotou Central Hospital, The 904 Hospital of PLA, Linyi People's Hospital, The 985 Hospital of PLA, Taiyuan, Shanxi, The First Affiliated Hospital with Nanjing Medical University, Tianjin TEDA Hospital, Liaocheng People's Hospital, Luoyang Central Hospital, Subei People's Hospital of Jiangsu Province, PLA 148 Hospital, Zibo, Shandong, Hebei General Hospital, Shengli Oilfield Hospital, Shenzhen Bao'an District People's Hospital, The First Hospital of Jilin University, Henan Provincial People's Hospital, Peking University Binhai Hospital, Beijing Tiantan Hospital, The Military General Hospital of Beijing, PLA, The First Affiliated Hospital of Shanxi Medical University, Beijing Luhe Hospital, Affiliated Hospital of Nantong University, The Affiliated Hospital Of Guizhou Medical University, Nanning Second People's Hospital, Chongqing Three Gorges Central Hospital, The First Affiliated Hospital of Dalian Medical University, The Fifth Central Hospital of Tianjin,TianJin, Yantaishan Hospital, Nanyang Central Hospital, Second Affiliated Hospital of Soochow University, Tianjin Huanhu Hospital, The Affiliated Hospital of Northwest University, Xi'an NO.3 Hospital | Basilar Artery Occlusion, Ischemic Stroke, Cerebrovascular Disorders | 09/21 | 06/22 | | |
| Recruiting | N/A | 60 | RoW | Automatic ischemic conditioning treatment instrument, Regular treatment | Capital Medical University | Cerebral Small Vessel Diseases | 12/21 | 12/21 | | |
NCT05207475: Safety and Efficacy of Remote Ischemic Conditioning on Cerebral Amyloid Angiopathy. (RIC-CAA) |
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| Recruiting | N/A | 30 | RoW | Remote ischemic conditioning | Capital Medical University | Cerebral Amyloid Angiopathy | 01/22 | 01/22 | | |
RIC-CAAH, NCT04757597: Remote Ischemic Conditioning for Cerebral Amyloid Angiopathy-related Intracerebral Hemorrhage |
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| Recruiting | N/A | 30 | RoW | Remote ischemic conditioning | Capital Medical University, Wangjing Hospital, China Academy of Chinese Medical Sciences, Bejing Fengtai You'anmen Hospital | Intracerebral Hemorrhage Lobar, Cerebral Amyloid Angiopathy | 03/22 | 06/22 | | |
NCT04470492: Study on Prevention and Treatment of Atherosclerotic Cerebral Occlusive Disease With Remote Ischemic Conditioning |
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| Not yet recruiting | N/A | 700 | NA | Doctormate®+Medical Management, Medical Management | Ji Xunming,MD,PhD | Cerebral Atherosclerosis | 08/22 | 12/22 | | |
NCT05291585: The Dedicated Venous Sinus Thrombectomy Stent for Endovascular Treatment of Cerebral Venous Sinus Thrombosis. |
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| Completed | N/A | 60 | RoW | the dedicated venous sinus thrombectomy stent, balloon catheter thrombectomy | Ji Xunming,MD,PhD | Cerebral Venous Sinus Thrombosis | 03/23 | 07/23 | | |
NCT05263531: Remote Ischemic Conditioning for Motor Recovery After Acute Ischemic Stroke |
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| Recruiting | N/A | 20 | RoW | remote ischemic conditioning | Ji Xunming,MD,PhD | Ischemic Stroke | 12/22 | 01/23 | | |
NCT05426707: Remote Ischemic Conditioning for the Treatment of Resistant Hypertension |
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| Not yet recruiting | N/A | 40 | NA | RIC, Sham-RIC | Ji Xunming,MD,PhD | Resistant Hypertension | 02/23 | 03/23 | | |
| Recruiting | N/A | 1000 | RoW | the level of biomarker in bood | Ji Xunming,MD,PhD | Ischemic Stroke | 03/23 | 12/25 | | |
NCT05448248: Multicenter Registry Study Of Cerebral Venous Thrombosis In China (RETAIN-CH) |
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| Completed | N/A | 3276 | RoW | | Capital Medical University, Brain Hospital of Hunan Provincial, The First Affiliated Hospital of Zhengzhou University, The Affiliated Hospital of Xuzhou Medical University, Guizhou Provincial People's Hospital | Cerebral Vein Thrombosis, Cerebral Venous Sinus Thrombosis | 12/23 | 12/23 | | |
NCT05342714: Remote Ischemic Conditioning for Chronic Cerebral Artery Occlusion |
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| Recruiting | N/A | 30 | RoW | Remote ischemic conditioning | Capital Medical University | Cerebral Artery Occlusion | 03/23 | 03/23 | | |
NCT05733338: The Effects of Intermittent Hypoxia on Acute Hypoxic Injury |
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| Recruiting | N/A | 100 | RoW | Intermittent Hypoxia, Sham Intermittent Hypoxia | Capital Medical University | Acute Mountain Sickness | 04/23 | 04/23 | | |
NCT05760950: A Cohort Study of Patients With Intracranial Hemorrhage |
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| Recruiting | N/A | 300 | RoW | Routine clinical treatment | Capital Medical University | Intracerebral Hemorrhage | 05/23 | 06/23 | | |
NCT05413837: Anatomical Variation of Cerebral Venous Sinus in Healthy Individuals |
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| Recruiting | N/A | 40 | RoW | anotomy and variation of venous sinus, the level of biomarker in bood | Capital Medical University | Venous Sinus Thrombosis, Cranial | 08/23 | 08/23 | | |
NCT05128422: Normobaric Hyperoxia Combined With Endovascular Treatment for Acute Ischemic Stroke |
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| Completed | N/A | 120 | RoW | Normobaric oxygen therapy | Capital Medical University | Stroke, Endovascular Treatment, Neuroprotection | 10/23 | 10/23 | | |
| Not yet recruiting | N/A | 136 | RoW | Remote ischemic conditioning (RIC), Sham remote ischemic conditioning (Sham-RIC) | Ji Xunming,MD,PhD | Acute Ischemic Stroke | 12/23 | 12/23 | | |
NCT05820165: Brain Imaging in Cerebral Venous Outflow Disturbance |
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| Recruiting | N/A | 80 | RoW | high-resolution 3D-T1, diffusion tensor imaging (DTI), resting-state functional magnetic resonance imaging (rs-fMRI), arterial spin labeling (ASL) perfusion magnetic resonance imaging (MRI), susceptibility-weighted images (SWIs) | Capital Medical University | Abnormal Cerebral Venous Sinus Morphology, Internal Jugular Vein Stenosis, Image | 12/23 | 12/24 | | |
NCT06584318: Exploratory Study of Intermittent Hypoxia Intervention on Colorectal Cancer |
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| Recruiting | N/A | 20 | RoW | Intermittent hypoxia intervention | Capital Medical University | Colorectal Cancer | 03/25 | 04/25 | | |
NBOL, NCT05039697: Normobaric Hyperoxia Combined With Endovascular Therapy in Patients With Stroke Within 6 Hours of Onset:Longterm Outcome |
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| Recruiting | N/A | 280 | RoW | oxygen | Capital Medical University | Stroke, Acute, Hypoxia-Ischemia, Brain, ENDOVASCULAR TREATMENT | 04/24 | 04/24 | | |
| Recruiting | N/A | 309 | RoW | Mechanical thrombectomy | Capital Medical University | Acute Ischemic Stroke, Basilar Artery Occlusion | 06/26 | 06/26 | | |
NCT05781880: Normobaric Hyperoxia Stabilizing Ischemic Penumbra |
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| Recruiting | N/A | 78 | RoW | Oxygen 100%, Normobaric hyperoxia | Ji Xunming,MD,PhD | Acute Ischemic Stroke | 11/24 | 12/24 | | |
MIRACLE-S, NCT06688162: Minimally Invasive Soft Channel Brain Haemorrhage Evacuation for Acute Basal Ganglia Haemorrhage--Small Hemorrhage Evacuation |
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| Not yet recruiting | N/A | 750 | NA | Usual Care, Minimally Invasive Soft Channel Brain Haemorrhage Evacuation (scMIS) | Capital Medical University, Fudan University, Linyi People's Hospital | Intracerebral Hemorrhage | 11/26 | 12/26 | | |
MIRACLE-L, NCT06688201: Minimally Invasive Soft Channel Brain Haemorrhage Evacuation for Acute Basal Ganglia Haemorrhage-- Large Hemorrhage Evacuation |
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| Recruiting | N/A | 550 | RoW | Other neurosurgical techniques, Minimally Invasive Soft Channel Brain Haemorrhage Evacuation | Capital Medical University, Linyi People's Hospital, Fudan University | Intracerebral Hemorrhage | 11/26 | 12/26 | | |
RICA-2, NCT05982015: Efficacy Study II on Remote Ischemic Conditioning for the Prevention of Stroke-Associated Pneumonia |
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| Completed | N/A | 1651 | RoW | Remote ischemic conditioning, Sham remote ischemic conditioning | Capital Medical University | Stroke | 09/24 | 12/24 | | |
| Not yet recruiting | N/A | 3000 | NA | | Capital Medical University, Beijing Municipal Science & Technology Commission | Cerebral Venous Sinus Thrombosis, Deep Cerebral Vein Thrombosis, Cortical Vein Thrombosis | 05/28 | 05/29 | | |
| Not yet recruiting | N/A | 1000 | RoW | | Capital Medical University | Intracranial Stenosis | 06/22 | 07/22 | | |
| Recruiting | N/A | 500 | RoW | Endovascular Treatment | Capital Medical University | Acute Ischemic Stroke | 12/22 | 06/23 | | |
Jia, Jianping |
NCT05908695: An Efficacy and Safety Study of Sodium Oligomannate (GV-971) for the Treatment of Alzheimer's Disease |
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| Recruiting | 4 | 1312 | RoW | GV-971, Placebo | Green Valley (Shanghai) Pharmaceuticals Co., Ltd. | Alzheimer's Disease | 06/29 | 12/29 | | |
NCT03789760: The Clinical Trial of Chinese Herbal Medicine (SaiLuoTong) Capsule |
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| Completed | 3 | 493 | RoW | SaiLuoTong capsule, The effects of SaiLuoTong capsule on VaD, placebo | Shineway Pharmaceutical Co.,Ltd | Vascular Dementia | 03/24 | 05/24 | | |
NCT03804229: Efficacy and Safety of Butylphthalide Soft Capsule for the Treatment of Vascular Dementia |
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| Active, not recruiting | 3 | 707 | RoW | Butylphthalide soft capsule, The effects of Butylphthalide soft capsule on VaD, Placebo soft capsule, Placebo | Capital Medical University, CSPC-NBP Pharmaceutical Co., Ltd. | Vascular Dementia | 10/24 | 02/25 | | |
| Recruiting | 3 | 1500 | Europe, RoW | Donanemab, (LY3002813), Placebo | Eli Lilly and Company | Alzheimer Disease, Dementia, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases, Tauopathies, Neurodegenerative Diseases, Neurocognitive Disorders, Mental Disorders | 04/27 | 04/27 | | |
NCT05811442: Study of 50561 in Patients With Mild or Moderate Alzheimer's Disease |
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| Recruiting | 2a | 60 | RoW | 50561 high dose, 50561 low dose, Placebo | Beijing Joekai Biotechnology LLC | Alzheimer's Disease | 05/24 | 06/24 | | |
NCT05269173: Efficacy and Safety of Flos Gossypii Flavonoids Tablet in the Treatment of Alzheimer's Disease |
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| Completed | 2 | 240 | RoW | Flos gossypii flavonoids tablet | Capital Medical University, Xinjiang Uygur Pharmaceutical Co., Ltd. | Alzheimer Disease | 08/24 | 11/24 | | |
NCT05670912: Efficacy and Safety of Wei Li Bai Capsules in the Treatment of Alzheimer's Disease |
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| Terminated | 2 | 105 | RoW | Wei Li Bai capsules, Placebo Comparator of Wei Li Bai capsules | Capital Medical University, China-Japan Friendship Hospital, Beijing Friendship Hospital | Alzheimer Disease | 11/24 | 11/24 | | |
NCT04850053: Detection of Alzheimer's Disease (AD)-Related Seeds for AD Diagnosis |
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| Recruiting | N/A | 1500 | RoW | | Capital Medical University, Shandong Provincial Hospital, Xiangya Hospital of Central South University, Zhejiang Provincial People's Hospital, Beijing Geriatric Hospital, Kaifeng Central Hospital, The First Affiliated Hospital of Chongqing Medical Universty, Huashan Hospital, First Affiliated Hospital Xi'an Jiaotong University, West China Hospital, Henan Provincial People's Hospital | Alzheimer's Disease | 12/24 | 12/24 | | |
| Recruiting | N/A | 300 | RoW | Ketogenic diet, placebo | Capital Medical University, West China Hospital, The First Affiliated Hospital of Zhengzhou University, Tianjin Huanhu Hospital, Shandong Provincial Hospital, Peking University Third Hospital, Shanghai Mental Health Center, Beijing Tiantan Hospital, Xiangya Hospital of Central South University, First Affiliated Hospital of Chongqing Medical University, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Sichuan Provincial People's Hospital, Brain Hospital Affiliated to Guangzhou Medical University, Sir Run Run Shaw Hospital, Zhejiang University | Alzheimer Disease | 05/25 | 05/25 | | |
NCT04575337: Study on Biomarkers for Early Diagnosis of Alzheimer's Disease |
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| Recruiting | N/A | 6000 | RoW | | Capital Medical University | Alzheimer Disease | 06/25 | 06/25 | | |
NCT05020106: The Diagnostic Cut-off Value of Core Biomarkers of Alzheimer's Disease |
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| Recruiting | N/A | 3200 | RoW | | Capital Medical University, Shandong Provincial Hospital, Second Affiliated Hospital, School of Medicine, Zhejiang University, Xiangya Hospital of Central South University, Huashan Hospital, The First Hospital of Jilin University | Alzheimer's Disease | 09/25 | 09/25 | | |
| Recruiting | N/A | 100000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Hunan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, Wuhan University Zhongnan Hospital, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Mild Cognitive Impairment(MCI), Alzheimer Disease, Late Onset, Familial Alzheimer Disease (FAD), Vascular Dementia (VaD), Normal Control, Non-Alzheimer Degenerative Dementia | 01/38 | 01/38 | | |
| Recruiting | N/A | 40000 | RoW | | Capital Medical University, Beijing Tiantan Hospital, Beijing Chao Yang Hospital, Fu Xing Hospital, Capital Medical University, Peking Union Medical College Hospital, Peking University First Hospital, Peking University Third Hospital, Chinese PLA General Hospital, China-Japan Friendship Hospital, Beijing Geriatric Hospital, The First Affiliated Hospital of Dalian Medical University, Fujian Medical University Union Hospital, Guangzhou Psychiatric Hospital, Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, Handan Central Hospital, Hebei General Hospital, First Hospital of Shijiazhuang City, Tangshan Worker's Hospital, Henan Provincial People's Hospital, Kaifeng Central Hospital, People's Hospital of Zhengzhou University, First Affiliated Hospital of Harbin Medical University, Tongji Hospital, People's Hospital Affiliated Hubei Medical University, Wuhan University Zhongnan Hospital, The Third Xiangya Hospital of Central South University, Xiangya Hospital of Central South University, The First Hospital of Jilin University, China-Japan Union Hospital, Jilin University, Subei People's Hospital of Jiangsu, Nantong University Affiliated Hospital, Mineral General Hospital, Xuzhou, Jiangxi Provincial People's Hopital, Anshan Central Hospital, The Affiliated Zhongshan Hospital of Dalian University, First Hospital of China Medical University, Baotou Central Hospital, General Hospital of Ningxia Medical University, The People's Hospital of Ningxia, The Affiliated Hospital of Qingdao University, The 960th Hospital of PLA, Qilu Hospital of Shandong University, Qilu Hospital of Shandong University (Qingdao), Shandong Provincial Hospital, Qingdao Municipal Hospital, The First Affiliated Hospital of Shanxi Medical University, Tang-Du Hospital, First Affiliated Hospital Xi'an Jiaotong University, Ruijin Hospital, RenJi Hospital, Shanghai Changzheng Hospital, Affiliated Hospital of North Sichuan Medical College, Tianjin Huanhu Hospital, Tianjin Medical University General Hospital, Traditional Chinese Medicine Hospital of Xinjiang Autonomous Region, Ningbo Medical Center Lihuili Hospital, First Affiliated Hospital of Wenzhou Medical University, First Affiliated Hospital of Zhejiang University, Shao Yifu Hospital of Zhejiang Medical University, Zhejiang Provincial People's Hospital, Daping Hospital and the Research Institute of Surgery of the Third Military Medical University, The Second Affiliated Hospital of Chongqing Medical University, The First Affiliated Hospital of Anhui Medical University, People's Hospital of Chongqing, Dongfang Hospital Beijing University of Chinese Medicine, Zigong No.1 Peoples Hospital | Alzheimer Disease, Familial Alzheimer Disease (FAD) | 01/38 | 01/38 | | |
Zhang, Yi |
NCT04771689: Buprenorphine/Naloxone Micro-Dosing for Postoperative Pain Management in Opioid-Tolerant Patients |
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| Not yet recruiting | 4 | 60 | US | Buprenorphine/Naloxone, Suboxone | Massachusetts General Hospital | Post-operative Pain | 12/22 | 12/22 | | |
| Recruiting | 4 | 20 | RoW | PCSK9 inhibitor (Alirocumab)plus standard medications, standard medications | Shanghai Tong Ren Hospital | Early PCSK9 Inhibitor on Ventricular Remodling | 12/24 | 06/25 | | |
NCT05292404: Impact of Early PCSK9 Inhibitor Treatment on Heart After Acute Myocardium Infarction |
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| Recruiting | 4 | 160 | RoW | alirocumab, conventional treatment | Shanghai Tong Ren Hospital, China Cardiovascular Association | Acute Myocardial Infarction | 06/25 | 12/25 | | |
NCT05003245: Compare the Efficacy and Safety of HLX04-O With Ranibizumab in Subjects With wAMD |
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| Recruiting | 3 | 388 | RoW | HLX04-O,recombinant anti-vascular endothelial growth factor (VEGF) humanized monoclonal antibody ophthalmic injection, Lucentis | Shanghai Henlius Biotech | Age Related Macular Degeneration | 08/23 | 03/24 | | |
nAMD, NCT05461339: TAB014 Compared to Lucentis® in Patients with Neovascular Age-related Macular Degeneration |
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| Active, not recruiting | 3 | 488 | RoW | TAB014 Monoclonal Antibody Injection, TAB014, Ranibizumab Injection [Lucentis], Lucentis | TOT Biopharm Co., Ltd., Zhaoke (Guangzhou) Ophthalmology Pharmaceutical Ltd. | Neovascular Age-related Macular Degeneration | 09/24 | 02/25 | | |