| Emery, Paul |
| Not yet recruiting | 4 | 106 | Europe | Benepali, Etanercept, Sulfasalazine, Methotrexate, Hydroxychloroquine | University of Leeds, Samsung Bioepis Co., Ltd. | Rheumatoid Arthritis | 02/23 | 02/23 | | |
NCT02012764: The CCP Study: Coordinated Programme to Prevent Arthritis - Can We Identify Arthritis at a Pre-clinical Stage ? |
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| Recruiting | N/A | 4000 | Europe | | University of Leeds, AbbVie | Inflammatory Arthritis, Rheumatoid Arthritis | 06/21 | 12/21 | | |
| Coates, Laura C |
NCT03739853: Severe Psoriatic Arthritis - Early intervEntion to Control Disease: the SPEED Trial |
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| Recruiting | 4 | 315 | Europe | Methotrexate, Sulfasalazine, Leflunomide, Adalimumab | University of Oxford | Psoriatic Arthritis | 08/24 | 02/25 | | |
| Completed | N/A | 503 | Europe | Questionnaire | University of Oxford, Amgen | Psoriatic Arthritis | 03/22 | 03/22 | | |
MONITOR, NCT03531073: Multicentre ObservatioNal Initiative in Treat to Target Outcomes in Psoriatic Arthritis |
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| Recruiting | N/A | 500 | Europe | Methotrexate | University of Oxford, National Institute for Health Research, United Kingdom | Psoriatic Arthritis | 08/24 | 02/25 | | |
| Recruiting | N/A | 25000 | Europe | PEST screening questionnaire | University of Oxford, University College Dublin | Psoriatic Arthritis, Psoriasis | 06/26 | 06/26 | | |
| Dye, Louise |
| Completed | N/A | 84 | Europe | Expectancy and gluten | Maastricht University, University of Leeds, Wageningen University | Non-celiac Gluten Sensitivity | 01/22 | 02/22 | | |
| Finlayson, Graham S |
| Completed | N/A | 175 | Europe | Sweetener and sweetness enhancer consumption | University of Leeds, University of Navarra, University of Liverpool, Københavns Universitet, Centre de Recherche en Nutrition Humaine Rhone-Alpe, University of Surrey, Bioatriki Healthcare Group | Eating Behavior | 09/23 | 11/23 | | |
| ANTHONEY, Alan |
| Recruiting | 3 | 800 | Europe | Futibatinib, Ivosidenib, Tibsovo, Zanidatamab, Trastuzumab, Zercepac, Neratinib, Nerlynx, Encorafenib, Braftovi, Binimetinib, Mektovi, Niraparib, Zejula, Cisplatin, Gemcitabine | UNICANCER, Cancer Research UK & UCL Cancer Trials Centre, Belgian Group of Digestive Oncology, National Cancer Institute, France, Cancer Research UK, Taiho Oncology, Inc., Servier, Zymeworks BC Inc., Accord Healthcare, Inc., Pierre Fabre Medicament | Biliary Tract Neoplasms | 06/27 | 06/28 | | |
| Active, not recruiting | 1/2 | 125 | Europe, US | ST101, Temozolomide, Radiation | Sapience Therapeutics | Glioblastoma, Melanoma Stage IV, Breast Cancer, Prostate Cancer, Glioblastoma Multiforme, GBM, Brain Cancer, Metastatic Breast Cancer, Metastatic Melanoma, Metastatic Prostate Cancer, Melanoma Recurrent, Prostate Cancer Metastatic, Recurrent Glioblastoma, Newly Diagnosed Glioblastoma | 12/24 | 12/25 | | |
| Gale, Christopher P |
NCT04657900: Predicting Patient-level New Onset Atrial Fibrillation |
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| Completed | N/A | 140000 | Europe | Observational | University of Leeds, British Heart Foundation | Atrial Fibrillation | 10/23 | 10/23 | | |
| Completed | N/A | 2159663 | Europe | Development of an algorithm | University of Leeds, British Heart Foundation, Clalit Health Services, Ben-Gurion University of the Negev | Atrial Fibrillation, Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases, Pathologic Processes | 10/23 | 10/23 | | |
| Gale, Chris P |
| Active, not recruiting | N/A | 13400 | Europe | Questionnaire | University of Leeds | Cardiovascular Diseases | 03/21 | 11/24 | | |
EMMACE-3X, NCT01955525: Long-term Follow-up of Health Related Quality of Life in Patients With Acute Coronary Syndrome |
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| Not yet recruiting | N/A | 3500 | Europe | | University of Leeds | Acute Coronary Syndrome | 11/23 | 11/23 | | |
OPTIMISE, NCT06444711: OPTIMISation of Cardio-renal-metabolic-pulmonary Disease Guideline Adherence in High Risk Community Dwelling Individuals |
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| Not yet recruiting | N/A | 138 | NA | NICE guidance | University of Leeds | Cardiovascular Diseases, Renal Disease, Metabolic Disease, Pulmonary Disease | 04/25 | 04/45 | | |
| Enrolling by invitation | N/A | 1955 | Europe | Development of an algorithm | University of Leeds, British Heart Foundation, Daiichi Sankyo, The Leeds Teaching Hospitals NHS Trust | Atrial Fibrillation, Heart Diseases, Cardiovascular Diseases | 10/24 | 02/25 | | |
| Enrolling by invitation | N/A | 14000 | Europe | Observational - no intervention given | University of Leeds, Japan Foundation for Aging and Health | Heart Failure | 01/25 | 01/25 | | |
| Recruiting | N/A | 4333 | Canada | Withholding feeds around transfusion, Continued feeds around transfusion | IWK Health Centre, Canadian Institutes of Health Research (CIHR), Imperial College London | Necrotizing Enterocolitis | 12/25 | 12/25 | | |
| Giannoudis, Peter |
NCT03884790: Pre-market Study to Evaluate Safety and Performance of GreenBone Implant (Long Bone Study) |
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| Terminated | N/A | 16 | Europe, RoW | surgical repair of long bone defects | GreenBone Ortho S.p.A. | Bone Substitutes, Bone Defect | 06/23 | 06/23 | | |
| Recruiting | N/A | 135 | Europe | Bone grafting for the treatment of surgically created bone defects or bone defects/voids resulting from traumatic injury to promote healing in the pelvis, upper and lower extremities. | GreenBone Ortho S.p.A. | Surgically Created Bone Defects or Bone Defects/Voids Resulting From Traumatic Injury | 10/27 | 10/27 | | |
| Not yet recruiting | N/A | 100 | NA | In'Oss™ (MBCP® Putty) | Advanced Medical Solutions Ltd. | Orthopedic Disorder, Trauma Injury, Extremity Injury | 03/27 | 03/27 | | |
FROST, NCT03598530: Fracture-Related Outcome Study for Operatively Treated Tibia Shaft Fractures |
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| Active, not recruiting | N/A | 1000 | Europe, US, RoW | Surgery, Operative, Surgical treatment | AO Clinical Investigation and Publishing Documentation, DePuy Synthes | Tibial Fracture, Fracture of the Tibia Type AO/OTA 42 | 03/25 | 12/25 | | |
NCT04112992: An International, Multicenter, Prospective Registry on Post-traumatic Long Bones Defects |
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| Recruiting | N/A | 600 | Europe, US, RoW | Any treatment that is used for a defect of any long bone | AO Innovation Translation Center | Limb Fracture, Bone Loss | 05/28 | 03/29 | | |
NCT05022485: Zimmer® Natural Nail® (ZNN) Bactiguard Tibia Post-Market Clinical Follow-up Study |
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| Recruiting | N/A | 500 | Europe, RoW | ZNN Bactiguard tibia | Zimmer Biomet | Tibial Fractures, Fracture Infection | 07/26 | 07/27 | | |
NCT04074382: FIT Study (Functional Outcomes In Trauma Study) |
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| Active, not recruiting | N/A | 440 | Europe | Online Questionnaires, Qualitative Interviews | The Leeds Teaching Hospitals NHS Trust | Patient Reported Outcome Measures, Recovery of Function, Rehabilitation, Disability Evaluation, Trauma Centers, Trauma Severity Indices, Advanced Trauma Life Support Care, Multiple Trauma/Injuries, Wounds and Injuries, Orthopedic Disorder, Surgery | 09/31 | 09/32 | | |
| Peckham, Daniel |
NCT06166056: A Study to Investigate the Safety, Tolerability, and Pharmacokinetics of Inhaled CHF6333 After Single Doses in Healthy Volunteers and After Single and Repeated Doses in Subjects With Bronchiectasis |
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| Recruiting | 1/2 | 45 | Europe | CHF6333, CHF6333 Placebo | Chiesi Farmaceutici S.p.A. | Bronchiectasis | 06/25 | 06/25 | | |
NCT06122025: Evaluation of Patient Access to People With Cystic Fibrosis (CF) and Healthcare Professionals |
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| Completed | N/A | 102 | Europe | Patient Access | The Leeds Teaching Hospitals NHS Trust, University of Leeds, Cystic Fibrosis Trust, Leeds Beckett University | Cystic Fibrosis | 10/19 | 10/19 | | |
(PCD), NCT06028607: Feasibility of Consumption of Nutritional Supplementation in Primary Ciliary Dyskinesia |
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| Completed | N/A | 15 | Europe | QD-27 | University of Leeds | Primary Ciliary Dyskinesia | 11/21 | 02/22 | | |
| Recruiting | N/A | 1000 | Europe | | Queen's University, Belfast, Cystic Fibrosis Foundation | Covid19, Cystic Fibrosis | 05/24 | 05/24 | | |
| Quirke, Philip |
NCT03986541: AREG, EREG and EGFR: Response to Anti-EGFR Agents in Colorectal Cancer |
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| Completed | N/A | 541 | Europe | Immunohistochemistry | University of Leeds, University of Liverpool, University of Manchester, Newcastle University, University of Nottingham, University of Sheffield | Colorectal Cancer Stage IV | 02/22 | 07/22 | | |
| Li, Lu |
GLORY, NCT04270591: Assessment of Anti-tumor and Safety in Glumetinib in Patients With c-MET-positive Non-Small Cell Lung Cancer |
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| Recruiting | 1/2 | 183 | Japan, US, RoW | Glumetinib, SCC244 | Haihe Biopharma Co., Ltd. | C-Met Exon 14 Mutation | 10/23 | 12/23 | | |
NCT05438329: First-in-human Study of DB-1305/BNT325 for Advanced/Metastatic Solid Tumors |
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| Recruiting | 1/2 | 902 | US, RoW | DB-1305/BNT325, DB-1305/BNT325 for Injection, Pembrolizumab, BNT327 | DualityBio Inc., BioNTech SE | Advanced Solid Tumor | 06/25 | 06/25 | | |
NCT05782881: High Risk Population of Cardiovascular Disease in Hubei Province Screening and Intervention Program |
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| Recruiting | N/A | 16000 | RoW | phone calls and encouraging patients' lifestyle change and medication adherence, Statin, Angiotensin-converting enzyme inhibitor, Angiotensin receptor neprilysin inhibitor, Glucagon-like peptide-1, Sodium-dependent glucose transporters 2 | Wuhan Union Hospital, China, Peking University First Hospital | Cardiovascular Diseases, Diabetes Mellitus, Type 2, Coronary Disease | 12/23 | 12/24 | | |
| Recruiting | N/A | 3000 | RoW | | Beijing Friendship Hospital | Drug-induced Liver Injury | 12/26 | 12/28 | | |
| Bosch, Christine |
NCT06164743: Phase 2: VVN461 Ophthalmic Solution for Post -Operative Ocular Inflammation After Cataract Surgery |
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| Completed | 2 | 91 | US | VVN461 Ophthalmic Solution 1.0%, VVN461 Ophthalmic Solution 0.5%, Vehicle | VivaVision Biotech, Inc | Inflammation | 05/24 | 05/24 | | |
| Pandit, Hermant |
| Active, not recruiting | N/A | 777 | Europe | Zimmer Persona Total Knee System, Primary Knee Replacement, Total Knee Arthroplasty, Total Knee Replacement | Zimmer, GmbH | Severe Knee Pain, Severe Knee Disability, Osteoarthritis, Rheumatoid Arthritis, Traumatic Arthritis, Polyarthritis | 12/27 | 12/27 | | |
| Sourbron, Steven |
| Recruiting | N/A | 134 | Europe | Hepatectomy, Liver resection, PVE or ALPPS | University of Leeds, The Leeds Teaching Hospitals NHS Trust, University of Sheffield | Hepatectomy, Liver Failure, Liver Cancer, Liver Metastases | 03/22 | 06/22 | | |
| Recruiting | N/A | 500 | Europe | MRI (magnetic resonance imaging), US (ultrasound), Sonography, Renal Biopsy, Kidney biopsy, percutaneous renal biopsy, Positron Emission Tomography (PET), PET scan, Microvascular Assessment | University of Leeds, University of Exeter, University Hospital, Bordeaux, University of Bari, University of Turku, Lund University, Swiss Institute of Bioinformatics | Diabetic Kidney Disease | 09/22 | 09/38 | | |
| Thorne, James L |
| Recruiting | N/A | 50 | Europe | Cholesterol Reducing Strawberry Yogurt Drink (Tesco Ltd), Low Fat Strawberry Yogurt Drinks (Morrisons Ltd) | University of Leeds, The Leeds Teaching Hospitals NHS Trust, University of Oslo | Hypercholesterolemia, Breast Cancer, Obesity | 12/21 | 12/21 | | |
| Sivan |
NCT04493775: Smartphone-based Brainwave Entrainment (BWE) Technology in Chronic Pain |
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| Not yet recruiting | N/A | 40 | Europe | Brainwave Entrainment | Helen Locke, University of Leeds | Chronic Pain | 10/23 | 10/24 | | |
| Sivan, Manoj |
| Recruiting | N/A | 7000 | Europe | No drug invervention | University of Leeds, Imperial College London, University of Oxford, University of Exeter, King's College London, University of Manchester, University of Dundee, Leeds Comunity Healthcare NHS Trust, Oxford University Hospitals NHS Trust, Imperial College Healthcare NHS Trust, University Hospitals, Leicester, Birmingham Community Healthcare NHS, NHS Tayside, Newcastle-upon-Tyne Hospitals NHS Trust, University Hospital of Wales | COVID-19 | 12/23 | 12/24 | | |
| Recruiting | N/A | 30 | Europe | Heart Rate Variability Biofeedback (HRV-B) | University of Leeds, University of Manchester, Leeds Comunity Healthcare NHS Trust | COVID-19 | 12/23 | 03/24 | | |
| Recruiting | N/A | 100 | Europe | | University of Leeds, Leeds Comunity Healthcare NHS Trust | COVID-19, Musculoskeletal Pain | 10/24 | 12/24 | | |
| Price, Oliver |
NCT06766175: Impact of Chronic Cough on Activities of Daily Living and Response to Acute High-intensity Exercise |
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| Recruiting | N/A | 129 | Europe | | University of Leeds, Hull York Medical School, Kings College Hospital London, Royal Brompton & Harefield NHS Foundation Trust | Chronic Cough (CC) | 06/26 | 12/26 | | |
NCT05976919: Evaluating Treatable Traits Across the Spectrum of Chronic Obstructive Airways Disease |
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| Recruiting | N/A | 100 | Europe | Pulmonary function testing, Cardiopulmonary exercise testing, Physical activity (daily step count), Dual-energy X-ray absorptiometry (body composition) | University of Leeds, The Leeds Teaching Hospitals NHS Trust | Airway Disease | 07/25 | 07/25 | | |
| Recruiting | N/A | 500 | Europe | | Royal Marsden NHS Foundation Trust, Royal Brompton & Harefield NHS Foundation Trust, Royal Marsden Partners West London Cancer Alliance, Imperial College London, University College London Hospitals, Lewisham and Greenwich NHS Trust, Guy's and St Thomas' NHS Foundation Trust, Epsom and St Helier University Hospitals NHS Trust, King's College Hospital NHS Trust, University College London (UCL) Cancer Institute, Institute of Cancer Research, United Kingdom, Francis Crick Institute, Royal Sussex County Hospital | Lung Cancer | 01/26 | 01/31 | | |
| Astill, Sarah |
| Completed | N/A | 5 | Europe | SCONE | University of Leeds, International Spinal Research Trust | Spinal Cord Injuries | 05/24 | 05/24 | | |
| Capozio, Antonio |
| Completed | N/A | 5 | Europe | SCONE | University of Leeds, International Spinal Research Trust | Spinal Cord Injuries | 05/24 | 05/24 | | |
