| Rickels, Michael |
| Active, not recruiting | 2 | 140 | Europe, US, RoW | Ladarixin, allosteric inhibitor of CXCL8 (IL-8), CXCR1 and CXCR2 receptors, Placebo | Dompé Farmaceutici S.p.A, Dompe farmaceutici s.p.a. | Recent Onset type1 Diabetes | 04/24 | 04/26 | | |
NCT04731272: GLP-1 Agonist Therapy in Cystic Fibrosis-Related Glucose Intolerance |
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| Recruiting | 2 | 30 | US | Dulaglutide 0.75Mg/0.5Ml Inj Pen | University of Pennsylvania, Children's Hospital of Philadelphia | Cystic Fibrosis, Pancreatic Insufficiency, Abnormal Glucose Tolerance, Diabetes | 06/26 | 06/27 | | |
| Active, not recruiting | 1 | 11 | US | Phentolamine, Regitine, Propranolol, Inderal, Placebo, Saline, Sodium Chloride Solution | University of Pennsylvania, National Institutes of Health (NIH), National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Type1diabetes, Hypoglycemia, Hypoglycemia Unawareness, Islet Cell Transplantation | 04/19 | 12/24 | | |
NCT01474889: Glucose Counterregulation in Long Standing Type 1 Diabetes |
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| Completed | N/A | 37 | US | RT-CGM, DexCom SEVEN PLUS, Guardian R-T, or FreeStyle Navigator. | University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Hypoglycemia Unawareness, Type 1 Diabetes, Healthy | 05/16 | 03/21 | | |
| Completed | N/A | 10 | US | MiniMed 670G system | University of Pennsylvania, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK) | Type1diabetes, Hypoglycemia Unawareness, Nocturnal Hypoglycemia, Hypoglycemia Night, Hypoglycemia | 05/22 | 10/24 | | |
NCT01851694: Beta-cell Response to Incretin Hormones in Cystic Fibrosis |
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| Recruiting | N/A | 45 | US | GLP-1, GIP, Glucose-dependent insulinotrophic polypeptide | University of Pennsylvania, Children's Hospital of Philadelphia | Cystic Fibrosis, Pancreatic Insufficiency | 12/25 | 12/25 | | |
2IQP, NCT05785832: A Randomized Trial Evaluating Control-IQ Technology in Adults With Type 2 Diabetes |
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| Completed | N/A | 319 | Canada, US | t:slim X2 insulin pump with Control-IQ technology 1.5 and Dexcom G6 CGM, Standard Therapy plus continuous glucose monitoring (CGM) | Tandem Diabetes Care, Inc., Jaeb Center for Health Research | Type 2 Diabetes Treated With Insulin | 09/24 | 09/24 | | |
| Not yet recruiting | N/A | 324 | Europe, US, RoW | Omnipod 5 or Medtronic 780G, My HypoCOMPaSS Education, HARPdoc Education | Milton S. Hershey Medical Center, National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK), University of Minnesota, University of Kentucky, University of Pennsylvania, AdventHealth, University of Leicester, University of Sheffield, University of Melbourne, Jaeb Center for Health Research, University of California, San Diego | Diabetes Mellitus, Type 1 | 06/27 | 12/27 | | |
NCT01852448: Genetics of Insulin and Incretins in Cystic Fibrosis |
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| Recruiting | N/A | 550 | US | Blood or Saliva Sample Collection | Children's Hospital of Philadelphia, University of Pennsylvania | Cystic Fibrosis | 07/25 | 07/25 | | |
| Mastrandrea, Lucy |
NCT02516657: Liraglutide in Adolescents With Type 1 Diabetes |
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| Active, not recruiting | 3 | 5 | US | Liraglutide, Victoza | University at Buffalo | Type 1 Diabetes | 12/23 | 12/24 | | |
| Recruiting | 3 | 300 | Europe, Canada, US, RoW | Tirzepatide, LY3298176, Placebo | Eli Lilly and Company | Obesity, Weight Gain | 05/27 | 06/27 | | |
| Active, not recruiting | 2 | 140 | Europe, US, RoW | Ladarixin, allosteric inhibitor of CXCL8 (IL-8), CXCR1 and CXCR2 receptors, Placebo | Dompé Farmaceutici S.p.A, Dompe farmaceutici s.p.a. | Recent Onset type1 Diabetes | 04/24 | 04/26 | | |
NCT05540132: Slow Digestible Carbohydrates and Exercise in Adolescents with Type 1 Diabetes |
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| Active, not recruiting | N/A | 20 | US | maltodextrin, super starch | State University of New York at Buffalo | Type 1 Diabetes, Hypoglycemia | 10/25 | 06/26 | | |
