| Liu, Yan |
NCT04381143: ASPIrin in Reducing Events in Dialysis ( ASPIRED ) |
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| Recruiting | 4 | 9000 | RoW | Aspirin 100 mg Oral Tablet, Matching Placebo | Guangdong Provincial People's Hospital, The George Institute | CKD (Chronic Kidney Disease) Stage 5D | 09/26 | 12/26 | | |
NCT05102149: Study to Evaluate the Safety and Efficacy of PB-201 in Treatment-naive Patients With Type 2 Diabetes Mellitus |
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| Recruiting | 3 | 672 | RoW | PB-201, Vildagliptin, PB-201 matched placebo, Vildagliptin matched placebo | PegBio Co., Ltd. | Type 2 Diabetes Mellitus (T2DM) | 11/23 | 04/25 | | |
NCT06350890: Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes |
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| Active, not recruiting | 3 | 408 | RoW | HTD1801, berberine ursodeoxycholate, Placebo | HighTide Biopharma Pty Ltd | T2DM (Type 2 Diabetes Mellitus) | 03/25 | 09/25 | | |
Symphony2, NCT06353347: Efficacy and Safety of Berberine Ursodeoxycholate (HTD1801) in Patients With Type 2 Diabetes Inadequately Controlled With Metformin |
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| Active, not recruiting | 3 | 551 | RoW | HTD1801, berberine ursodeoxycholate, Placebo | HighTide Biopharma Pty Ltd | Type 2 Diabetes Mellitus | 03/25 | 12/25 | | |
NCT06775860: ICP-332 in Subjects with Moderate to Severe Atopic Dermatitis |
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| Recruiting | 3 | 552 | RoW | ICP-332 Tablets, ICP-332 Placebo Tablets | Beijing InnoCare Pharma Tech Co., Ltd. | Atopic Dermatitis | 11/26 | 12/26 | | |
NCT06126991: Organ Protective Effect of Cetirizine In Patients With Severe Burns |
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| Recruiting | 1/2 | 32 | RoW | Cetirizine, Midazolam and Fentanyl | Ruijin Hospital | Burns | 12/24 | 12/25 | | |
NCT05232357: Endoscopic Vital Nerve Staining in Gastrointestinal Diseases |
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| Recruiting | 1 | 100 | RoW | Sodium thiosulfate and Methylene blue solution, NaS2O3.5H2O and Methylene blue injection (2ml:20mg) | Affiliated Hospital to Academy of Military Medical Sciences | Gastrointestinal Neoplasms, Abnormality of Enteric Nervous System Morphology | 05/22 | 05/22 | | |
NCT05045911: An Endoscopic Barbed-clips Suturing for Colorectal ESD |
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| Recruiting | N/A | 35 | RoW | Endoscopic Barbed-clips Suturing | Affiliated Hospital to Academy of Military Medical Sciences | Colorectal Neoplasms | 12/21 | 12/21 | | |
NCT05192538: A Novel Endoloop Pre-test to Treat Gastroesophageal Reflux |
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| Recruiting | N/A | 30 | RoW | Endoscopic endoloop pre-test treatment | Affiliated Hospital to Academy of Military Medical Sciences, Beijing 302 Hospital, Beijing Hospital | GERD, Reflux Esophagitis | 04/22 | 05/22 | | |
| Recruiting | N/A | 270 | RoW | Enhanced physical activity intervention, Standard education | Shanghai Jiao Tong University School of Medicine | Overweight and Obesity, Physical Activity | 05/22 | 05/23 | | |
NCT05196243: Multimodal Imaging Based on Pathological and Genomic Characteristics |
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| Recruiting | N/A | 200 | RoW | Patients diagnosed as gastrointestinal mucosal lesions | Affiliated Hospital to Academy of Military Medical Sciences | Mitochondrial DNA Mutation, Endoscopy | 06/22 | 07/24 | | |
NCT05190042: Clinical Study on Continuous Suture of Endoscopic Mucosal Defects |
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| Completed | N/A | 62 | RoW | Cotinuous suture, Clips | Affiliated Hospital to Academy of Military Medical Sciences | Colonic Polyp, Gastrointestinal Neoplasms | 06/22 | 07/22 | | |
NCT05189912: Clinical Study on the Application of a Specimen Retrieving Bag to Reduce the Polyp Fragmentation Rate |
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| Completed | N/A | 204 | RoW | Specimen retrieving bag, Sucking polyps to the instrument channel port | Affiliated Hospital to Academy of Military Medical Sciences | Colonic Polyp | 07/22 | 08/22 | | |
NCT05320497: Transparent Cap-assisted SpyGlass for Biliary Stricture |
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| Recruiting | N/A | 10 | RoW | Transparent cap | Affiliated Hospital to Academy of Military Medical Sciences | Bile Duct Stricture, Endoscopic Retrograde Cholangiopancreatography, Biliary Disease, Biliary Tract Neoplasms | 07/22 | 07/22 | | |
NCT05531396: Agility Training on Physical Performance, Cognitive Function and Brain Activities in Elderly |
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| Not yet recruiting | N/A | 30 | NA | Agility Training, Health Education | National Taiwan University Hospital | Elderly, Healthy | 05/23 | 06/23 | | |
NCT05375123: Reference Range for Tissue Motion Tracking of Mitral Annulus Displacement in Chinese Han Singleton Pregnancies |
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| Recruiting | N/A | 660 | RoW | Ultrasound image acquisition | First Hospital of China Medical University | Pregnancy | 06/23 | 06/24 | | |
NCT05547841: Normal Reference Value for Echocardiography in Chinese Han Pregnancies |
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| Recruiting | N/A | 680 | RoW | Echocardiography acquisition | First Hospital of China Medical University | Pregnancy | 08/23 | 08/24 | | |
Endo-mmfi, NCT06236594: Application of Multimodal Endoscopic Functional Imaging Technology in the Diagnosis of Common Gastrointestinal Diseases |
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| Recruiting | N/A | 100 | RoW | | Beijing 302 Hospital | Gastrointestinal Disease | 12/24 | 12/24 | | |
| Recruiting | N/A | 10 | RoW | Compare color information and mucosal microvascular density | Affiliated Hospital to Academy of Military Medical Sciences | CAG - Chronic Atrophic Gastritis, EGC - Early Gastric Cancer | 12/23 | 12/23 | | |
NCT06285955: Clinical Trial of Metal-Reinforced Teeth Designed for Endoscopic Clips |
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| Completed | N/A | 10 | RoW | | Beijing 302 Hospital | Pilot Study, Clips | 06/24 | 07/24 | | |
NCT06331923: Assessing the Effectiveness of Continuous Glucose Monitoring in Enhancing Surgical Outcomes for Patients with Diabetes |
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| Recruiting | N/A | 10168 | RoW | Continuous glucose monitoring (CGM) device | Beijing Tsinghua Chang Gung Hospital, Peking University International Hospital, Wang Jing Hospital, ZhuHai Hospital, Beijing Hospital, Siyang County Hospital of Traditional Chinese Medicine, Second Hospital of Shanxi Medical University, Henan Provincial Chest Hospital, Fuzhou First Hospital, Pinggu Hospital of Beijing Traditional Chinese Medicine Hospital, The First Affiliated Hospital of Anhui University of Chinese Medicine, The First Affiliated Hospital of Zhengzhou University, Mindong Hospital of Ningde, The Fifth Hospital of Xiamen, People's Hospital of Ningxia Hui Autonomous Region, The First People's Hospital of Changzhou, The Fifth hospital of Deyang, Suzhou Municipal Hospital, Tang-Du Hospital, Yiyang Central Hospital, First Affiliated Hospital of Xinjiang Medical University, Peng Ding Shan Shi Zhong Yi Yi Yuan, Yueyang Central Hospital, The First People's Hospital of Lianyungang, Haimen District Traditional Chinese Medicine Hospital, The 910th Hospital, The Second Affiliated Hospital of Zhejiang Chinese Medical University, Beijing Tiantan Hospital, Affiliated Hospital of Jiangsu University, Liaocheng People's Hospital, Beijing Chao Yang Hospital, Jilin City Hospital of Chemical Industry, Creen Hospital-465, Wuhan Central Hospital, Air Force Military Medical University, China, Shanghai Tong Ren Hospital, Beijing Anzhen Hospital, Emergency General Hospital, Beijing Tongren Hospital, Civil Aviation General Hospital, Peking University Shougang Hospital, The First Affiliated Hospital of Anhui Medical University, Chinese PLA Central Hospital | Comprehensive Complication Index | 10/25 | 12/25 | | |
NCT05476627: Risk Factors and Multiomics Study of Chronic Kidney Disease Caused by Metabolic Diseases |
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| Recruiting | N/A | 200 | RoW | Biomarkers | Peking Union Medical College Hospital | Chronic Kidney Diseases, Hypertension, Diabetes Mellitus, Hyperuricemia, Obesity | 07/25 | 07/27 | | |
NCT05537363: Agility Training and Its Relations in Elderly Adults With and Without MCI |
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| Not yet recruiting | N/A | 240 | NA | Health education, Multicomponent training, Agility training | National Taiwan University Hospital | Elderly Adults, Mild Cognitive Impairment, Healthy | 10/25 | 12/25 | | |
| Recruiting | N/A | 1200 | RoW | Yiqi Fumai Lyophilized Injection(YQFM) | China Academy of Chinese Medical Sciences, National Natural Science Foundation of China | Acute Heart Failure, Complementary Medicine, Chinese Medicine | 11/25 | 11/25 | | |
NCT05457062: Analysis the Vocs in Upper GI Bleeding Patients |
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| Recruiting | N/A | 500 | RoW | | Affiliated Hospital to Academy of Military Medical Sciences | Upper GI Bleeding | 12/22 | 06/23 | | |
NCT05685849: Evaluation of Maternal Fetal Cardiac Structure and Function in Pregnancies With Cardiovascular Disease |
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| Recruiting | N/A | 200 | RoW | Echocardiography | First Hospital of China Medical University | Pregnancy | 01/25 | 01/25 | | |
| Mu, Yiming |
NCT05963022: A Study of Tirzepatide (LY3298176) in Chinese Participants With Type 2 Diabetes (SURPASS-CN-MONO) |
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| Completed | 3 | 168 | RoW | Tirzepatide, LY3298176, Placebo | Eli Lilly and Company | Type 2 Diabetes | 10/24 | 10/24 | | |
ATTAIN-2, NCT05872620: A Study of Orforglipron in Adult Participants With Obesity or Overweight and Type 2 Diabetes |
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| Active, not recruiting | 3 | 1500 | Europe, US, RoW | Orforglipron, LY3502970, Placebo | Eli Lilly and Company | Obesity, Overweight, Type 2 Diabetes | 08/25 | 08/25 | | |
ATTAIN-1, NCT05869903: A Study of Orforglipron (LY3502970) in Adult Participants With Obesity or Overweight With Weight-Related Comorbidities |
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| Active, not recruiting | 3 | 3000 | Europe, Japan, US, RoW | Orforglipron, LY3502970, Placebo | Eli Lilly and Company | Obesity, Overweight, Overweight or Obesity | 07/25 | 07/27 | | |
TRIUMPH-4, NCT05931367: A Study of Retatrutide (LY3437943) Once Weekly in Participants Who Have Obesity or Overweight and Osteoarthritis of the Knee |
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| Active, not recruiting | 3 | 405 | Europe, Canada, US, RoW | Retatrutide, LY3437943, Placebo | Eli Lilly and Company | Obesity, Overweight, Osteo Arthritis Knee | 02/26 | 03/26 | | |
NCT06481085: To Evaluate Efficacy and Safety of HDM1002 Tablets in Adults With Type 2 Diabetes Mellitus |
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| Not yet recruiting | 2 | 318 | RoW | HDM1002 50 mg, HDM1002, HDM1002 100 mg, HDM1002 200 mg, HDM1002 400 mg, HDM1002 200 mg BID, Placebo, Matching placebo for group A to group E | Hangzhou Zhongmei Huadong Pharmaceutical Co., Ltd. | Type 2 Diabetes | 04/25 | 04/25 | | |
NCT06671821: Long-term Efficacy and Safety of HRS-7535 Tablets in Obese Subjects |
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| Not yet recruiting | 2 | 180 | RoW | HRS-7535 | Shandong Suncadia Medicine Co., Ltd. | Chronic Weight Management | 08/25 | 08/25 | | |
| Xu, Jianming |
| Recruiting | 3 | 570 | RoW | KL-140, Placebo | Sichuan Kelun Pharmaceutical Research Institute Co., Ltd. | Metastatic Colorectal Cancer | 12/20 | 12/23 | | |
NCT03236649: The Phase III Study of Icaritin Versus Sorafenib in PD-L1 Positive Advanced Hepatocellular Carcinoma Subjects |
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| Terminated | 3 | 89 | RoW | Icaritin, Sorafenib Tosylate Tablets | Beijing Shenogen Biomedical Co., Ltd, Cancer Institute and Hospital, Chinese Academy of Medical Sciences, Eastern Theater General Hospital,QinHuai District Medical Area, Peking University Cancer Hospital & Institute, Chinese PLA General Hospital, Beijing Hospital, General Hospital of Chinese Armed Police Forces, Guang'anmen Hospital of China Academy of Chinese Medical Sciences, Jinan Central Hospital, Linyi Cancer Hospital, The First Affiliated Hospital of Anhui Medical University, Anhui Provincial Hospital, The First Affiliated Hospital with Nanjing Medical University, The Affiliated Tumor Hospital of Nantong University, Nantong, Jiangsu Province, China, Nanfang Hospital of Southern Medical University, First People's Hospital of Foshan, Affiliated Cancer Hospital & Institute of Guangzhou Medical University, Tianjin Medical University Cancer Institute and Hospital, The Fourth Hospital of Hebei Medical University, Hunan Cancer Hospital, The First Hospital of Jilin University, 307 Hospital of PLA, Fudan University, Henan Cancer Hospital, Jilin Provincial Tumor Hospital, First Affiliated Hospital of Harbin Medical University, First Affiliated Hospital Bengbu Medical College, The First Affiliated Hospital of Soochow University, Tongji Hospital, Beijing YouAn Hospital | Hepatocellular Carcinoma (HCC) | 02/22 | 02/22 | | |
NCT04342910: Study to Evaluate the Efficacy and Safety of Camrelizumab and Apatinib in Patients With GC/GEJC |
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| Recruiting | 3 | 550 | RoW | camrelizumab, SHR-1210, Apatinib Mesylate, Paclitaxel, Irinotecan | Jiangsu HengRui Medicine Co., Ltd. | Gastric Cancer | 04/22 | 09/22 | | |
KL140-â…¢-02-CTP, NCT04835142: Comparison of A140 and Erbitux Combined With mfolfox6 to Evaluate Efficacy and Safety of First-line Treatment for Ras Wild-type mCRC |
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| Completed | 3 | 688 | RoW | Double blind control period A140, KL-140, Open single period A140 | Sichuan Kelun Pharmaceutical Research Institute Co., Ltd. | Metastatic Colorectal Cancer | 03/23 | 01/24 | | |
NCT04415853: Study of Larotinib in Unresectable Advanced or Recurrent Esophageal Cancer |
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| Recruiting | 3 | 416 | RoW | Lerotinib, Z650, Irinotecan/Tegafur, Irinotecan Hydrochloride Injection/Tegafur Gimeracil Oteracil Potassium Capsule | Sunshine Lake Pharma Co., Ltd. | Esophageal Cancer | 08/23 | 11/23 | | |
NCT04409223: Efficacy and Safety of Famitinib Versus Sunitinib in the Treatment of Advanced Gastrointestinal Stromal Tumour Patients After Failure of Imatinib |
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| Terminated | 3 | 185 | RoW | Famitinib capsules, Sunitinib Capsules, Sutent | Jiangsu HengRui Medicine Co., Ltd. | Gastrointestinal Stromal Tumors | 03/22 | 03/22 | | |
NCT06432296: Treatment of Malignant Ascites Caused by Advanced Epithelial Solid Tumors With M701 Bispecific Antibody |
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| Recruiting | 3 | 270 | RoW | M701, paracentesis | Wuhan YZY Biopharma Co., Ltd. | Malignant Ascites | 08/25 | 11/25 | | |
| Active, not recruiting | 3 | 408 | RoW | KN046, placebo | Jiangsu Alphamab Biopharmaceuticals Co., Ltd | Advanced Pancreatic Ductal Adenocarcinoma | 04/24 | 08/24 | | |
NCT05459844: A Study Comparing Treatment With Lutetium[177Lu] Oxodotreotide Injection to Octreotide LAR in Patients With GEP-NETs |
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| Active, not recruiting | 3 | 196 | RoW | Lutetium[177Lu] Oxodotreotide Injection, 177Lu-DOTA0-Tyr3-Octreotate, Octreotide LAR, SANDOSTATIN LAR, Octreotide | Sinotau Pharmaceutical Group | Neuroendocrine Tumors | 12/24 | 12/28 | | |
| Active, not recruiting | 2/3 | 405 | RoW | SCT-I10A, SCT510, Sorafenib 200mg | Sinocelltech Ltd. | Hepatocellular Carcinoma | 04/24 | 09/24 | | |
NCT05427383: KN026 in Combination With Chemotherapy in HER2 Positive Gastric Cancer Subjects Who Have Failed First-line Therapy |
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| Recruiting | 2/3 | 286 | RoW | KN026/Placbo Injection, Paclitaxel Injection, Docetaxel Injection, Irinotecan Injection | Shanghai JMT-Bio Inc. | Stomach Cancer | 11/25 | 11/26 | | |
NCT06266091: Treat Malignant Ascites Caused by Gastrointestinal or Ovarian Cancer With M701 Bispecific Antibody |
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| Active, not recruiting | 2 | 80 | RoW | M701, paracentesis | Wuhan YZY Biopharma Co., Ltd. | Malignant Ascites | 03/24 | 12/24 | | |
NCT04466254: Efficacy and Safety Study of Combination of CPGJ602 and Chemotherapy, in First Line, With Wild KRAS/NRAS/BRAF in Metastatic Colorectal Cancer |
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| Recruiting | 2 | 75 | RoW | CPGJ602, cetuximab | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | Metastatic Colorectal Cancer | 12/21 | 03/22 | | |
NCT06158516: A Study of Surufatinib as Adjuvant Therapy for Pancreatic Neuroendocrine Tumors |
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| Not yet recruiting | 2 | 100 | RoW | Surufatinib, Placebo | Changhai Hospital | Pancreatic Neuroendocrine Tumor | 11/26 | 11/26 | | |
NCT06247956: Study of SHR-8068 Combined With Adebrelimab and Platinum-containing Chemotherapy in the Treatment of Advanced Gastric and Esophageal Cancer |
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| Recruiting | 2 | 240 | RoW | SHR-8068;Adebrelimab;Oxaliplatin;Capecitabine Tablets;Paclitaxel Injection;Cisplatin Injection, Adebrelimab;Oxaliplatin;Capecitabine Tablets;Paclitaxel Injection;Cisplatin Injection | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Gastric Adenocarcinoma and Esophageal Squamous Cell Carcinoma | 06/25 | 12/25 | | |
| Recruiting | 2 | 40 | RoW | AB-106 | AnHeart Therapeutics Inc. | Solid Tumor | 04/24 | 12/26 | | |
SPH5030-201, NCT06434597: A Clinical Study of SPH5030 Tablets in the Treatment of Her2-positive/Mutated Biliary Tract OR Colorectal Cancer Patients. |
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| Recruiting | 2 | 60 | RoW | SPH5030 | Shanghai Pharmaceuticals Holding Co., Ltd | Biliary Tract or Colorectal Cancer With Her2-positive/Mutated | 12/26 | 12/26 | | |
NCT06505395: A Trial to Assess Efficacy, Safety, Pharmacokinetics of Octreotide Subcutaneous Injection in Patients With Gastroentero-pancreatic Neuroendocrine Tumor (GEP-NET) |
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| Recruiting | 2 | 90 | RoW | SYHX2008 injection, Sandostatin LAR@ | CSPC ZhongQi Pharmaceutical Technology Co., Ltd. | Gastrointestinal Neuroendocrine Pancreatic Tumor | 08/27 | 08/28 | | |
NCT04353375: Phase 2 Study of HMPL-453 Tartrate in Advanced Intrahepatic Cholangiocarcinoma |
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| Recruiting | 2 | 128 | RoW | HMPL-453 | Hutchmed | Advanced Intrahepatic Cholangiocarcinoma | 06/25 | 12/25 | | |
NCT05879055: A Study of PM8002 in Combination With Chemotherapy in Patients With NEN |
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| Recruiting | 2 | 60 | RoW | PM8002, FOLFIRI | Biotheus Inc. | Neuroendocrine Neoplasm | 01/27 | 01/28 | | |
NCT06237400: A Study of ZG19018 in Patients With KRAS G12C Mutant Advanced Solid Tumors. |
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| Recruiting | 1/2 | 110 | RoW | ZG19018 | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | KRAS G12C Mutant Advanced Solid Tumors | 05/25 | 05/25 | | |
NCT03888092: Z650 in Advanced Esophageal Squamous Cell Carcinoma With EGFR Over Expression or Gene Amplification |
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| Completed | 1/2 | 81 | RoW | Z650, Larotinib | Sunshine Lake Pharma Co., Ltd. | Esophageal Squamous Cell Carcinoma | 12/22 | 12/22 | | |
| Recruiting | 1/2 | 198 | RoW | AK109+AK104 | Akeso | Advanced Solid Tumor | 12/24 | 12/24 | | |
NCT04699643: FGFR4 Inhibitor EVER4010001 in Combination With PD-1 Inhibitor Pembrolizumab in Patients With Advanced Solid Tumors |
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| Recruiting | 1/2 | 80 | RoW | EVER4010001, Pembrolizumab | EverNov Medicines (Zhuhai Hengqin) Co., Ltd, Medidata Solutions | Advanced Solid Tumors | 06/23 | 06/23 | | |
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NCT06237413: A Study of ZG2001 in Participants With KRAS Mutated Advanced Solid Tumours |
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| Recruiting | 1/2 | 110 | RoW | ZG2001 Tosilate Tablets, ZG2001 | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | Solid Tumor, KRAS Mutation-Related Tumors | 02/26 | 02/26 | | |
ZG005-004, NCT06372626: Study of ZG005 in Combination With Etoposide and Cisplatin in Participants With Advanced Neuroendocrine Carcinoma. |
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| Recruiting | 1/2 | 93 | RoW | ZG005, Etoposide, Cisplatin, Placebo | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | Neuroendocrine Carcinoma | 07/26 | 08/26 | | |
NCT06440057: Dose Escalation Study of ZG006 in Participants With Advanced Small Cell Lung Cancer or Neuroendocrine Carcinoma, Followed by Dose Expansion Study in Participants With Neuroendocrine Carcinoma. |
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| Recruiting | 1/2 | 78 | RoW | ZG006 | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | Neuroendocrine Carcinoma | 05/26 | 07/26 | | |
NCT05173142: HMPL-453 (FGFR Inhibitor) in Combination With Chemotherapy or Anti-PD-1 Antibody in Advanced Solid Tumors |
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| Recruiting | 1/2 | 141 | RoW | HMPL-453, gemcitabine and cisplatin, toripalimab, Docetaxel | Hutchison Medipharma Limited | Solid Tumor | 09/24 | 08/25 | | |
NCT05805956: IMM2902 in Patients With Advanced Solid Tumors Expressing HER2 |
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| Recruiting | 1/2 | 105 | RoW | IMM2902 | ImmuneOnco Biopharmaceuticals (Shanghai) Inc. | Advanced Solid Tumor, Advanced Lung Cancer, Advanced Gastric Carcinoma, Advanced Cholangiocarcinoma | 10/24 | 10/24 | | |
NCT05584800: Study of ZGGS18 in Patients With Advanced Solid Tumors |
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| Recruiting | 1/2 | 222 | RoW | ZGGS18 for Injection | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | Advanced Solid Tumor | 11/25 | 11/25 | | |
NCT02489201: A Study of Donafenib Monotherapy in Advanced Oesophageal Cancer |
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| Terminated | 1b | 19 | RoW | donafenib tosilate tablets, CM4307 | Suzhou Zelgen Biopharmaceuticals Co.,Ltd | Oesophageal Cancer | 10/20 | 10/20 | | |
NCT04501744: A Study of M701 (EpCAM and CD3) in Malignant Ascites |
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| Recruiting | 1 | 42 | RoW | Cohort 1 of M701, Cohort 2 of M701, Cohort 3 of M701, Cohort 4 of M701, Cohort 5 of M701, Cohort 6 of M701, Cohort 7 of M701 | Wuhan YZY Biopharma Co., Ltd. | Malignant Ascites, Cancer | 01/21 | 06/21 | | |
NCT05123209: Safety and Efficacy Evaluation of IM83 CAR-T Cells for Patients With Advanced Liver Tumors |
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| Recruiting | 1 | 12 | RoW | IM83 CAR-T cells, The second-line treatment of liver cancer | Beijing Immunochina Medical Science & Technology Co., Ltd. | Liver Cancer | 08/23 | 08/23 | | |
MIZAR, NCT05417750: A Phase I Study on Autologous Tumor Infiltrating Lymphocytes Injection (GC101 TIL) for the Treatment of Advanced Malignant Solid Tumors |
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| Recruiting | 1 | 60 | RoW | TIL therapy | Shanghai Juncell Therapeutics | Tumor Infiltrating Lymphocytes, Safety, Advanced Solid Tumor, Immunotherapy, Efficacy, Adverse Drug Event | 11/25 | 04/26 | | |
NCT04998422: A Study of HG381 Administered to Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 57 | RoW | HG381, HG381 for Injection | HitGen Inc. | Advanced Solid Tumor | 06/24 | 12/24 | | |
NCT04965077: Treatment of Advanced and Metastatic Solid Tumors With MIL97 |
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| Recruiting | 1 | 62 | RoW | Recombinant Humanized Monoclonal Antibody MIL97 for Injection | Beijing Mabworks Biotech Co., Ltd. | Advanced or Metastatic Solid Tumor | 12/25 | 12/26 | | |
NCT05275062: Clinical Trial to Evaluate the Safety and Efficacy of IM92 CAR-T Cells Therapy in Patients With Advanced Gastric or Pancreatic Adenocarcinoma |
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| Recruiting | 1 | 6 | RoW | IM92 CAR-T cells | Beijing Immunochina Medical Science & Technology Co., Ltd. | Advanced Solid Tumors, Gastric Cancer, Esophagogastric Junction Cancer, Pancreatic Cancer | 03/24 | 05/24 | | |
NCT05382377: NKG2D CAR-T(KD-025) in the Treatment of Advanced NKG2DL+ Solid Tumors |
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| Recruiting | 1 | 18 | RoW | KD-025 | jianming xu, KAEDI | CRC, Solid Tumor | 05/24 | 05/26 | | |
NCT05583201: NKG2D/CLDN18.2 CAR-T(KD-496) in the Treatment of Advanced NKG2DL+/CLDN18.2+ Solid Tumors |
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| Recruiting | 1 | 18 | RoW | KD-496 | jianming xu, KAEDI | Gastric Cancer, Pancreatic Cancer, Solid Tumor | 06/24 | 06/26 | | |
| Recruiting | 1 | 556 | RoW | IBI363 + chemotherapy, IBI363 + Investigator's Choice SOC | Innovent Biologics (Suzhou) Co. Ltd. | Advanced Malignancies | 06/25 | 12/26 | | |
NCT05352542: GPC3-targeting CART Cell in Treatment of Advanced Hepatocellular Carcinoma |
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| Terminated | 1 | 10 | RoW | GPC3 Targeting CART Cells | jianming xu, Nanjing Legend Biotech Co. | Advanced Hepatocellular Carcinoma | 07/24 | 07/24 | | |
NCT05427396: A Phase I Clinical Study of Recombinant Humanized Anti-BTLA Monoclonal Antibody (JS004) Injection Combined With Toripalimab Injection in Patients With Advanced Solid Tumors |
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| Recruiting | 1 | 198 | RoW | JS004, Toripalimab Injection | Shanghai Junshi Bioscience Co., Ltd., Sponsor GmbH | Liver Cancer, Esophageal Squamous Cell Carcinoma, Gastric Adenocarcinoma, Cervical Cancer, MSI-H Colorectal Cancer | 08/24 | 08/25 | | |
NCT05191667: AN0025 and Chemoradiotherapy Combination in Esophageal Cancer |
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| Suspended | 1 | 32 | RoW | AN0025, Paclitaxel, Carboplatin, Radiotherapy | Adlai Nortye Biopharma Co., Ltd. | Esophageal Cancer | 12/24 | 12/25 | | |
| Recruiting | 1 | 37 | RoW | ET0111 | Etern BioPharma (Shanghai) Co., Ltd | Advanced Solid Tumor | 12/24 | 05/25 | | |
| Recruiting | 1 | 60 | RoW | SG1906 | Hangzhou Sumgen Biotech Co., Ltd. | Locally Advanced Unresectable or Metastatic Solid Tumors | 02/25 | 08/25 | | |
| Completed | 1 | 19 | RoW | SHR-A2009 | Suzhou Suncadia Biopharmaceuticals Co., Ltd. | Advanced Solid Tumor | 04/24 | 04/24 | | |
NCT05946226: A Phase I Trial to Evaluate the Safety of IMC002 in Advanced Digestive System Tumors |
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| Recruiting | 1 | 18 | RoW | IMC002 injection, Autologous Claudin 18.2 specific CAR-T cell injection | Suzhou Immunofoco Biotechnology Co., Ltd | Advanced Digestive System Tumor | 12/25 | 12/25 | | |
NCT05192460: Safety and Efficacy of Personalized Neoantigen Vaccine in Advanced Gastric Cancer, Esophageal Cancer and Liver Cancer |
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| Recruiting | N/A | 30 | RoW | neoantigen tumor vaccine with or without PD-1/L1, PGV002 mRNA Vaccine | jianming xu, NeoCura | Gastric Cancer, Esophageal Cancer, Liver Cancer | 12/24 | 06/25 | | |
NCT05940181: A Safety and Efficacy Study of XH001 Combined With Sintilimab Injection in Advanced Solid Tumors |
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| Recruiting | N/A | 9 | RoW | XH001+ sintilimab | jianming xu, NeoCura | Solid Tumor | 05/25 | 12/25 | | |
| Mi, Weidong |
NCT04837170: Safety and Efficacy Evaluation of S (+) - Ketamine in Adults |
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| Not yet recruiting | 4 | 12000 | NA | Conventional therapy + S (+)-Ketamine, Conventional therapy + S-ketamine, Conventional therapy + Esketamine, Conventional therapy, Routine treatment | Chinese PLA General Hospital, Jiangsu Provincial People's Hospital, Beijing Hospital, The Affiliated Hospital of Qingdao University, Renmin Hospital of Wuhan University, First Affiliated Hospital Xi'an Jiaotong University, First Affiliated Hospital, Sun Yat-Sen University, Shengjing Hospital, Southern Medical University, China | Postoperative Pain, Adults, Anesthesia | 06/22 | 06/22 | | |
NCT04947761: Modified Tian Wang Bu Xin Dan Hydrogel Patch in Preventing Postoperative Delirium in Elderly Patients |
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| Recruiting | 4 | 200 | RoW | modified Tian Wang Bu Xin Dan hydrogel patch, modified Cheonwangbosimdan hydrogel patch, placebo patch | Chinese PLA General Hospital | Postoperative Delirium | 12/22 | 12/22 | | |
NCT04834427: Safety and Efficacy Evaluation of S (+) - Ketamine in Children |
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| Enrolling by invitation | 4 | 3000 | RoW | Conventional therapy + S (+)-Ketamine, Conventional therapy + S-ketamine, Conventional therapy + Esketamine, Conventional therapy, Routine treatment | Chinese PLA General Hospital, Southern Medical University, China, Beijing Children's Hospital, Shanghai Children's Medical Center, Hunan Children's Hospital | S-ketamine, Esketamine, Acute Pain, Postoperative Pain, Analgesia, Hyperalgesia, Delirium, Depression, Anxiety, Children | 12/24 | 12/24 | | |
NCT06551259: Effect of Dexmedetomidine on Central Nervous System Complications in Patients Undergoing Cardiac Surgery |
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| Completed | 4 | 200 | NA | Dexmedetomidine, physiological saline | Chinese PLA General Hospital | Randomized Controlled Trial, Dexmedetomidine | 07/24 | 08/24 | | |
| Recruiting | 1 | 64 | RoW | HR18034, subjects will receive HR18034., Naropin, Naropin, 0.5% Injectable Solution | Jiangsu HengRui Medicine Co., Ltd. | Inguinal Hernia Repair | 05/21 | 05/21 | | |
NCT06502912: Association Between Iron Reserves and Perioperative Neurocognitive Disorders |
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| Completed | N/A | 12984 | NA | no intervention | Chinese PLA General Hospital | Perioperative Neurocognitive Disorders | 12/21 | 12/21 | | |
NCT06307717: Effects of Volatile Anaesthetics on Incidence of Postoperative Depression and Anxiety in Elderly Patients |
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| Completed | N/A | 8000 | RoW | volatile anaesthetic (sevoflurane, isoflurane, desflurane), The blank group was without the use of any inhalation anesthetics | Chinese PLA General Hospital, Beijing Tsinghua Changgeng Hospital, Peking University First Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Xiangya Hospital of Central South University, Beijing Anzhen Hospital, Central South University, Peking University People's Hospital, Zhejiang University, Fudan University, Sun Yat-sen University, Wuhan Union Hospital, China, China-Japan Friendship Hospital, The Affiliated Hospital Of Guizhou Medical University, First Affiliated Hospital of Xinjiang Medical University, First Affiliated Hospital of Guangxi Medical University, Taihe Hospital | Cohort Studies | 10/21 | 04/22 | | |
NCT06495840: Postoperative Anxiety and Depression Among Older Chinese Patients |
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| Completed | N/A | 8590 | RoW | no intervention | Chinese PLA General Hospital, Beijing Tiantan Hospital, Peking University First Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Xiangya Hospital of Central South University, Beijing Anzhen Hospital, Central South University, Peking University People's Hospital, Zhejiang University, Fudan University, Sun Yat-sen University, Wuhan Union Hospital, China, China-Japan Friendship Hospital, The Affiliated Hospital Of Guizhou Medical University, First Affiliated Hospital of Xinjiang Medical University, First Affiliated Hospital of Guangxi Medical University, Taihe Hospital, Zhejiang Provincial People's Hospital, Shanghai Zhongshan Hospital | Depression, Anxiety, Elderly Patients, Non-cardiac Surgery | 04/22 | 04/22 | | |
| Completed | N/A | 37230 | RoW | | Weidong Mi | Postoperative Infection, Geriatrics, Prediction | 06/23 | 09/23 | | |
NCT04911530: Perioperative Database of Chinese Elderly Patients |
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| Recruiting | N/A | 10000 | RoW | no intervention | Chinese PLA General Hospital, Beijing Tiantan Hospital, Peking University First Hospital, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Xiangya Hospital of Central South University, Beijing Anzhen Hospital, Central South University, Peking University People's Hospital, Zhejiang University, Fudan University, Sun Yat-sen University, Wuhan Union Hospital, China, China-Japan Friendship Hospital, The Affiliated Hospital Of Guizhou Medical University, First Affiliated Hospital of Xinjiang Medical University, First Affiliated Hospital of Guangxi Medical University, Taihe Hospital, Zhejiang Provincial People's Hospital, Shanghai Zhongshan Hospital | Perioperative Complications, Perioperative/Postoperative Complications, Perioperative Adverse Events | 04/22 | 12/25 | | |
NCT06362408: Effect of Dexmedetomidine on Postoperative Mental Disorders and Long-term Survival in Elderly Patients |
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| Completed | N/A | 6000 | RoW | Dexmedetomidine | Chinese PLA General Hospital, Beijing Tiantan Hospital, First Affiliated Hospital of Guangxi Medical University, The Affiliated Hospital Of Guizhou Medical University, The Affiliated Nanjing Drum Tower Hospital of Nanjing University Medical School, Wuhan Union Hospital, China, Fudan University, Peking University People's Hospital, The First Xiangya Hospital of Central South University, Central South University, China-Japan Friendship Hospital | Cohort Studies | 05/23 | 06/23 | | |
NCT06547281: Machine Learning Prediction of Multiple Infections in Elderly Surgical Patients |
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| Completed | N/A | 42540 | RoW | | Weidong Mi | Postoperative Infection, Geriatrics, Prediction | 12/23 | 03/24 | | |
NCT05742737: Frailty Index as An Indicator Associated With Postoperative Adverse Outcomes In The Older Population |
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| Completed | N/A | 12000 | RoW | Frailty Index | Weidong Mi | Frailty | 04/22 | 04/23 | | |
NCT06756750: Clinical Characteristics and Risk Factors for In-Hospital Mortality in Surgical Patients with Abdominal Sepsis |
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| Completed | N/A | 476 | RoW | | Chinese PLA General Hospital | Sepsis, Glucocorticoid | 12/23 | 05/24 | | |
NCT06608030: Effect of Esketamine on Perioperative Negative Mood in Patients Undergoing Cardiac Valve Surgery |
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| Recruiting | N/A | 142 | RoW | Esketamine, normal saline | Chinese PLA General Hospital, Beijing Tiantan Hospital, The Sixth Medical Center of Chinese PLA General Hospital | Depression, Anxiety, Cardiac Surgery, S-ketamine | 08/25 | 08/25 | | |
NCT05507268: Predictive Nomogram for Postoperative Acute Kidney Injury in Older Patients Undergoing Noncardiac Surgery |
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| Recruiting | N/A | 50000 | RoW | no intervention | Chinese PLA General Hospital | Postoperative Acute Kidney Injury | 12/22 | 12/22 | | |
| Hong, Dai |
NCT04468997: The Study of Drug 601 in Patients With Wet Age-related Macular Degeneration (wAMD) |
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| Recruiting | 1 | 67 | RoW | Drug 601 | Sunshine Guojian Pharmaceutical (Shanghai) Co., Ltd. | Wet Age-related Macular Degeneration | 03/21 | 09/21 | | |
| Mu, Yimin |
NCT05047471: To Improve the Ability of Early Screening and Diagnosis in Patients With Diabetic Nephropathy |
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| Enrolling by invitation | N/A | 10000 | RoW | | Yiming Mu | Diabetic Kidney Disease | 05/23 | 06/23 | | |
| Lui, Dai Hong |
NCT05278507: Comparing Arrow PICC Catheters w/ Arrowga+rd Blue Advanced Protection Performance and Safety to Unprotected PICC's |
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| Recruiting | N/A | 444 | RoW | Arrowga+rd Blue Advance Protection PICC Placement, Sham Comparator PICC placement | Teleflex | Peripherally Inserted Central Catheter | 06/23 | 06/23 | | |
