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Trial + Data / Events	Status	Ph	N	Region	Interventions	Sponsor	Conditions	Primary compl	Study compl
Trivedi, Palak
FARGO, NCT06286709: FAecal Microbiota Transplantation in primaRy sclerosinG chOlangitis	Recruiting	2	58	Europe	Faecal Microbiota Transplant, FMT Placebo	University of Birmingham, PSC Support, Life Arc	Primary Sclerosing Cholangitis, Inflammatory Bowel Diseases	04/26	07/26
PACIFIC, NCT05525520 / 2021-002526-25: Study to Evaluate EP547 in Subjects With Cholestatic Pruritus Due to Primary Biliary Cholangitis or Primary Sclerosing Cholangitis	Completed	2	62	Europe, Canada, US, RoW	EP547, Placebo	Escient Pharmaceuticals, Inc, Escient Pharmaceuticals, Inc.	Pruritus	07/24	09/24
SPRING, NCT04595825 / 2019-002945-39: CM-101 in PSC Patients -The Study	Active, not recruiting	2	68	Europe, US, RoW	Anti-human CCL24 monoclonal antibody (CM-101), Placebo	ChemomAb Ltd., ChemomAb Ltd	Primary Sclerosing Cholangitis	09/24	09/25
VISTAS, NCT04663308 / 2020-003027-41: A Study to Evaluate Efficacy and Safety of an Investigational Drug Named Volixibat in Patients With Itching Caused by Primary Sclerosing Cholangitis (PSC)	Recruiting	2	200	Europe, Canada, US, RoW	Volixibat, SHP626, Placebo	Mirum Pharmaceuticals, Inc., Mirum Pharmaceuticals, Inc.	Primary Sclerosing Cholangitis	09/25	12/25
PSC-Vanc, NCT05376228: A Systems Biology Approach for Identification of Host and Microbial Mechanisms and Druggable Targets for the Treatment of PSC-IBD	Recruiting	N/A	15	Europe	Oral Vancomycin	University Hospital Birmingham NHS Foundation Trust	Inflammatory Bowel Diseases, Primary Sclerosing Cholangitis	02/23	04/23