| Leftheriotis, Georges PN |
| Recruiting | N/A | 99 | Europe | study treatment PPI, Placebo comparator | Centre Hospitalier Universitaire de Nice | Pseudoxanthoma Elasticum | 12/26 | 09/27 | | |
| Gagnadoux, Frédéric |
| Recruiting | 4 | 378 | Europe | pirfenidone and nintedanib, pirfenidone or nintedanib | Hospices Civils de Lyon, Ministry of Health | Progressive Idiopathic Pulmonary Fibrosis | 01/26 | 01/26 | | |
| Recruiting | 3 | 86 | Europe | bosentan, placebo | University Hospital, Grenoble | Ischemic Optic Neuropathy | 12/23 | 12/25 | | |
BEconneCTD-ILD, NCT06572384: A Study of the Efficacy and Safety of Belimumab in Adults With Interstitial Lung Disease Associated With Connective Tissue Disease |
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| Recruiting | 3 | 440 | Europe, Japan, US, RoW | Belimumab, BENLYSTA, GSK1550188, Placebo | GlaxoSmithKline | Lung Diseases, Interstitial | 10/28 | 12/28 | | |
AKAPI, NCT06585020: Amikacin Liposome Inhalation Suspension for Treatment of Mycobacterium Xenopi Pulmonary Infection |
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| Not yet recruiting | 2 | 190 | Europe | Arikayce, standard treatment | Centre Hospitalier Universitaire, Amiens, University Hospital, Angers, Hospital Avicenne, University Hospital, Bordeaux, University Hospital, Brest, CH Compiègne, Créteil Hospital, Centre Hospitalier Universitaire Dijon, University Hospital, Grenoble, Centre Hospitalier le Mans, Hôpital de la Croix-Rousse, APHM - Nord, Hôpital Saint Joseph, CH Mulhouse, CH Orléans, Tenon Hospital, Paris, Hôpital Necker-Enfants Malades, CH PERPIGNAN, Poitiers University Hospital, CH Pontoise, CHU de Reims, Rennes University Hospital, CHU de Rouen - Accueil, Central Hospital Saint Quentin, IHU Strasbourg, University Hospital, Tours, CH Abbeville, CH Cannes | Mycobacterium; Xenopi, Lung Diseases | 08/26 | 08/27 | | |
SLEEPCONNECT, NCT04054180: Multimodal Remote Monitoring and Integrated Educational Program in OSA Patients Initiating Continuous Positive Airway Pressure (CPAP): |
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| Terminated | N/A | 41 | Europe | CPAP associated with connected devices: blood pressure monitor , scales and activity monitor | University Hospital, Grenoble, SEFAM MEDICAL (Villiers les Nancy, France) | Obstructive Sleep Apnea Syndrome | 01/24 | 02/24 | | |
EXODYS, NCT04459182: Circulating Exosomes and Endothelial Dysfunction in Patients With Obstructive Sleep Apneas Hypopneas Syndrome |
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| Completed | N/A | 99 | Europe | ENDOPAT | University Hospital, Angers | Endothelial Dysfunction | 07/23 | 07/23 | | |
SUNSAS, NCT05057975: Validation of an Integrated Digital Solution (SUNrise®) Versus Polysomnography for Obstructive Sleep Apnea Diagnosis |
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| Completed | N/A | 848 | Europe | Sunrise, polysomnography | Sunrise, ICUREsearch | Obstructive Sleep Apnea | 10/24 | 10/24 | | |
NCT02346305: Cohort of Respiratory Failure Patients Treated for the First Time With Non-Invasive Ventilation at Home |
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| Recruiting | N/A | 3000 | Europe | Non-invasive ventilation | Association Nationale pour les Traitements A Domicile, les Innovations et la Recherche | Respiratory Insufficiency | 12/24 | 12/24 | | |
RAMBO, NCT05015153: Impact on Quality of Life with Pulmonary RehAbilitation After Pulmonary EMBOlism: Study |
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| Recruiting | N/A | 112 | Europe | Pulmonary rehabilitation (PR) | University Hospital, Brest | Pulmonary Embolism, Quality of Life and Dyspnea | 12/26 | 02/28 | | |
PANTHERA, NCT05461417: Long-term Efficacy, Tolerance and Compliance of Panthera D-SAD® Mandibular Advancement Orthosis in Sleep Apnea |
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| Active, not recruiting | N/A | 337 | Europe | D-SAD | Panthera Dental Inc., AXONAL | Sleep Apnea, Obstructive | 05/29 | 05/29 | | |
| Recruiting | N/A | 400 | Europe | CPAP, MAD | ResMed | OSA | 10/22 | 10/26 | | |
| Abraham, Pierre |
| Recruiting | N/A | 300 | Europe | transcutaneous oxygen pressure recording at rest | University Hospital, Angers | Critical Limb Ischemia | 10/22 | 10/22 | | |
| Completed | N/A | 100 | Europe | MyotonPRO | University Hospital, Angers | Compartment Syndrome | 03/23 | 03/23 | | |
| Recruiting | N/A | 1000 | Europe | Ultrasound, angiography, questionnaires, Transcutaneous oximetry, plethysmography, Electromyogram, Standard X-Ray | University Hospital, Angers | Thoracic Outlet Syndrome | 12/25 | 12/25 | | |
| Recruiting | N/A | 30 | Europe | exercise oximetry, thallium scintigraphy | University Hospital, Angers | Peripheral Arterial Disease | 06/21 | 06/21 | | |
| Baufreton, Christophe |
| Recruiting | N/A | 5000 | Europe | | Medtronic Cardiac Surgery | Cardiovascular Diseases | 12/25 | 12/25 | | |
| Mercat, Alain |
DE-RISK WF, NCT04696406: Multicenter, Multinational, Clinical Trial of the Performance of RESPINOR DXT to Identify Patients at Increased Risk of Weaning Failure |
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| Completed | N/A | 193 | Europe | RESPINOR DXT | Respinor AS, The Research Council of Norway | Respiratory Failure | 03/22 | 04/22 | | |
OWED, NCT02539732: Prediction of Outcome of Weaning From Mechanical Ventilation Using the Electrical Activity of the Diaphragm |
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| Recruiting | N/A | 110 | Europe, Canada | | Unity Health Toronto | Respiratory Insufficiency | 12/21 | 12/21 | | |
| Recruiting | N/A | 300 | Europe, Canada, RoW | | Unity Health Toronto | ARDS, Acute Hypoxemic Respiratory Failure | 08/22 | 08/22 | | |
PROMIZING, NCT02447692: Proportional Assist Ventilation for Minimizing the Duration of Mechanical Ventilation: The Study |
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| Completed | N/A | 575 | Europe, Canada, RoW | PSV ventilation strategy, PAV+ ventilation strategy | Lawson Health Research Institute, Canadian Institutes of Health Research (CIHR), Medtronic, Canadian Critical Care Trials Group | Critically Ill, Acute Respiratory Failure | 07/24 | 07/24 | | |
| Active, not recruiting | N/A | 17 | Europe | ECCO2R | Assistance Publique - Hôpitaux de Paris, Ministry of Health, France, Xenios AG | COPD Acute Exacerbation | 05/24 | 03/25 | | |
TGV-MOA, NCT06119516: Transpulmonary Pressure - Guided Mechanical Ventilation in Morbidly Obese ARDS Patients: a Feasibility Study. |
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| Recruiting | N/A | 40 | Europe | Esophageal pressure-guided strategy, | Assistance Publique - Hôpitaux de Paris, Ministry of Health, France | ARDS, Human, Obesity, Morbid | 04/26 | 07/26 | | |
| Kouatchet, Achille |
COTRIVAP, NCT05696093: Efficacy of Cotrimoxazole as a De-escalation Treatment of Ventilator-Associated Pneumonia in Intensive Care Unit |
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| Recruiting | 3 | 628 | Europe | cotrimoxazole, standard antibiotic therapy | Assistance Publique - Hôpitaux de Paris | Ventilator Associated Pneumonia | 10/26 | 12/26 | | |
| Calès, Paul |
NCT04615091: Non-invasive Methods and Surgical Risk Stratification in Cirrhotics Undergoing Elective Extrahepatic Surgery |
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| Recruiting | N/A | 250 | Europe, Canada, US, RoW | | Azienda Ospedaliera Universitaria Integrata Verona | Advanced Chronic Liver Disease, Surgery--Complications | 10/21 | 08/22 | | |
| Pellier, Isabelle |
CAALL-F01, NCT02716233: A French Protocol for the Treatment of Acute Lymphoblastic Leukemia (ALL) in Children and Adolescents |
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| Recruiting | 3 | 1578 | Europe | pegaspargase 1250 IU/m2 x 2, ONCASPAR 1250 IU/m2 x 2, pegaspargase 2500 IU/m2 x 1, ONCASPAR 2500 IU/m2 x 1 | Assistance Publique - Hôpitaux de Paris, Shire | Acute Lymphoblastic Leukemia | 04/26 | 04/26 | | |
| Recruiting | 2/3 | 225 | Europe | Melphalan or Melphalan + Topotecan, Alkeran, Topotecan Accord; Topotecan Hospira chemotherapy, etoposide, carboplatin and vincristine or local ophthalmological treatment without IV chemotherapy, etoposide, carboplatin and vincristine chemotherapy, Carboplatin administered on Day 1, platinum-based chemotherapy, Thermotherapy (local treatment), Thermotherapy after carboplatin administered on Day 1, Cryotherapy (local treatment), Iodine-125 plaques (local treatment), Intravitreal Melphalan chemotherapy injections (local treatment) | Institut Curie, Fondation Rothschild Paris | Retinoblastoma | 01/35 | 01/36 | | |
| Active, not recruiting | 2 | 133 | Europe | VP16, carboplatin, etoposide, vepesid, chemotherapy, Melphalan, Alkeran, chemotherapy, VP16, carboplatin, vincristin, etoposide, vepesid, leurocristine, Oncovin, chemotherapy, Carboplatin + laser day 1 (chemothermotherapy), Carbo-laser, platinum-based chemotherapy, Laser (local treatment), Laser diode, cryoapplication (local treatment), I125 radioactive plaques (local treatment), intravitreal Melphalan (local treatment) | Institut Curie, Fondation Rothschild Paris | Retinoblastoma, Children, Retinal Neoplasm | 01/23 | 09/35 | | |
| Recruiting | 2 | 185 | Europe | Observation, Low risk group, Etoposide, Intermediate risk sub group 1, Vincristine, Intermediate risk sub group 2, Orbital irradiation, High risk group, Carboplatin, Cyclophosphamide, Thiotepa, Cytapheresis, Peripheral bood stem cell transplantation | Institut Curie | Retinoblastoma | 03/30 | 09/30 | | |
| Recruiting | 1/2 | 455 | Europe | Ribociclib, Kisqali, LEE011, Topotecan, Hycamtin, Temozolomide, Temodar, Everolimus, Afinitor, votubia, Adavosertib, AZD1775, Carboplatin, Paraplatin, Olaparib, Lynparza, Irinotecan, Camptosar, CPT-11, Vistusertib, AZD2014, Nivolumab, Opdivo, Cyclophosphamide, Cytoxan, Selumetinib, Koselugo, Enasidenib, Idhifa, Lirilumab, BMS-986015, Fadraciclib, CYC065, Cytarabine, Arabinosylcytosine, Cytosar-U, Dexamethasone, Decadron, Dexasone, Diodex, Hexadrol, Maxidex, Ceralasertib, AZD6738, Futibatinib, Tas-120, Capmatinib, Tabrecta, INC280, Avelumab, BAVENCIO, Peposertib | Gustave Roussy, Cancer Campus, Grand Paris, National Cancer Institute, France | Pediatric Cancer | 02/31 | 02/31 | | |
CURALASE01, NCT04596410: Photobiomodulation Protocols in the Analgesia of Chemotherapy-induced Oral Mucositis in Children |
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| Recruiting | N/A | 406 | Europe | LLLT applied every other day, LLLT applied daily | University Hospital, Toulouse | Mucositis Oral | 01/24 | 02/24 | | |
| Not yet recruiting | N/A | 50 | Europe | Sampling bone tissue and blood | Rennes University Hospital | Leukemia, Lymphoblastic, Acute, Pediatric | 02/35 | 06/35 | | |
| Recruiting | N/A | 300 | Europe, RoW | Collection of blood sample or saliva, Collection of a tumor sample taken before the participation of the patient in study, Collection of blood sample if tumor sample is not available | University Hospital, Angers | Predisposition, Genetic, Cancer Childhood, Development Delay | 02/25 | 08/25 | | |
| Active, not recruiting | N/A | 2093 | Europe, RoW | Hydroxycarbamide, Siklos, Hydroxyurea | Theravia, International Clinical Trials Association | Sickle Cell Disease | 08/25 | 08/25 | | |
MICCHADO, NCT03496402: Biological Characterisation of High Risk CHildhood Cancer in Children, Adolescents and Young Adults |
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| Active, not recruiting | N/A | 600 | Europe | Sampling on blood, bone marrow and cerebrospinal fluid | Institut Curie | Neuroblastoma, Rhabdomyosarcoma, Ewing Sarcoma Family of Tumors, Osteosarcoma, Leukemia, Central Nervous System Tumor | 04/27 | 08/27 | | |
| Recruiting | N/A | 3500 | Europe | data collection | University Hospital, Bordeaux | Immune Thrombocytopenia, Autoimmune Hemolytic Anemia, Evans Syndrome | 12/29 | 12/29 | | |
ALARM3, NCT05772559: Acute Myeloid Leukemia At Initial Diagnosis and/or Relapse in Children, Teenagers and Young Adults: Molecular Profiling, Multidrug Testing and MSC Interaction Studies |
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| Recruiting | N/A | 500 | Europe | Collection of blood sample of bone marrow (cohort 1), Collection of blood sample of bone marrow (cohort 2 and 3) | Assistance Publique - Hôpitaux de Paris | Acute Myeloid Leukemia, Genetic Predisposition to Disease | 05/33 | 05/33 | | |
| Lasocki, Sigismond |
| Active, not recruiting | 3 | 42 | Europe | Erythropoietin, Placebo | University Hospital, Angers | Anemia, Intensive Care | 09/22 | 12/22 | | |
| Recruiting | 3 | 360 | Europe | Milrinone 1 Mg/mL Solution for Injection, Corotrope, Saline solution for injection, Sodium Chloride 0.9% | University Hospital, Angers | Vasospasm | 08/23 | 02/24 | | |
HAP-DEX, NCT06269900: Dexamethasone for Treating Severe Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype |
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| Recruiting | 3 | 450 | Europe | Dexamethasone, Placebo | Nantes University Hospital | Hospital Acquired Pneumonia | 03/26 | 08/26 | | |
| Not yet recruiting | 3 | 1218 | Europe | direct IV injection, combination of Ketamine and Propofol | Nantes University Hospital | Rapid Sequence Induction | 03/27 | 04/27 | | |
PROPHYLOXITIN, NCT05755789: Intermittent Cefoxitin Administration Versus Loading Bolus Followed by Continuous Infusion for the Prevention of Surgical Site Infection in Colorectal Surgery |
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| Recruiting | 3 | 2000 | Europe | Loading bolus of cefoxitin, Intermittent cefoxitin, Continuous infusion of placebo, Continuous infusion of cefoxitin, Intermittent placebo | Poitiers University Hospital | Antibiotic Prophylaxis, Colorectal Surgery | 05/25 | 06/25 | | |
| Completed | 3 | 700 | Europe | Inhaled sedation with sevoflurane, intravenous sedation with propofol | University Hospital, Clermont-Ferrand | Acute Respiratory Distress Syndrome | 10/23 | 10/24 | | |
TREAT-HAP, NCT05914584: "Baricitinib for Treating Hospital-acquired Pneumonia in Critically Ill Patients With a Proinflammatory Phenotype. |
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| Not yet recruiting | 3 | 450 | Europe | Baricitinib 4 MG | Nantes University Hospital | Hospital-acquired Pneumonia | 08/25 | 12/25 | | |
MICAREA, NCT06150326: Medical Honey for Wound Treatment in Intensive Care. (MICARéa) Randomized, Controlled, Single-center Pilot Study. |
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| Not yet recruiting | 2/3 | 60 | NA | medical honey Activon® 25g Tube, medical honey, standard of care, recommendation of HAS ( french administration) | University Hospital, Angers | Wound Heal, Critical Illness | 01/26 | 04/26 | | |
| Not yet recruiting | N/A | 5000 | Europe | questionnaire filling | Centre Hospitalier Universitaire de NÄ«mes | Critical Illness, Covid19, Stress Disorders, Post-Traumatic | 09/22 | 09/22 | | |
GOAL, NCT03461900: Guided Fluid-balance Optimization With Mini-fluid chALlenge During Septic Shock |
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| Completed | N/A | 535 | Europe | Minifluid challenge, Usual practice | University Hospital, Brest | Septic Shock | 08/23 | 01/24 | | |
IRON KID, NCT03231085: Comparison of the Rate of Preoperative Haemoglobin After Administration of Epoetin Alpha Associated With an Oral Medical Supplementation Versus Intravenous Before Surgery of Craniosynostosis at the Child |
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| Completed | N/A | 100 | Europe | Ferrous fumarate or ferrostrane, Intravenous ferric carboxymaltose. | University Hospital, Montpellier | Craniosynostosis | 04/24 | 10/24 | | |
| Not yet recruiting | N/A | 150 | NA | non invasive hemoglobin measure | University Hospital, Angers | Anemia | 01/26 | 01/26 | | |
| Not yet recruiting | N/A | 160 | NA | | University Hospital, Angers | Anemia | 12/25 | 12/26 | | |
CRIC, NCT06019897: Impact of Tubing Colonization on the Incidence of Central Venous Catheter Infection |
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| Not yet recruiting | N/A | 200 | NA | | University Hospital, Angers | Catheter-Related Infections, Catheter Complications, Catheter Infection, Catheter-related Bloodstream Infection, Catheter Related Complication | 11/24 | 01/25 | | |
HOMI-LUNG-HAP, NCT06602934: Long-term Alterations of Host-microbiome Interactions and Cardiovascular and Respiratory Diseases Progression After Pneumonia |
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| Recruiting | N/A | 300 | Europe | Blood samples, Oropharyngeal swabs, Calcium score (CT scan), ECG, Cardiopulmonary exercise test, spirometry, plethysmography, pulmonary absorption of carbon monoxide in a single inspiration, and 6-minute walk test | Nantes University Hospital | Hospital Acquired Pneumonia (HAP), Cardiovascular and Respiratory Disease | 01/29 | 05/29 | | |
| Recruiting | N/A | 702 | Europe | No ventilation with face mask, Ventilation with face mask | Nantes University Hospital | Morbid Obesity, Ventilation Therapy; Complications | 09/25 | 09/25 | | |
| Recruiting | N/A | 770 | Europe | High flow Oxygenation, Standard oxygen | University Hospital, Brest | Chest Trauma, High Flow Oxygenation | 02/26 | 02/26 | | |
| Recruiting | N/A | 660 | Europe | Extubation readiness clinical score, Standard of care | University Hospital, Clermont-Ferrand, AZUREA Network (www.azurea.org), ANARLF Network, Direction Générale de l'Offre de Soin (DGOS) | Mechanical Ventilator Weaning, Acute Brain Injury, Altered Level of Consciousness, Mechanical Ventilation, Airway Control | 02/27 | 10/27 | | |
ATLANREA, NCT02714387: Non Traumatic Neuro-Vascular Diseases Critical Complications : a Prospective Cohort Study |
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| Recruiting | N/A | 5000 | Europe | Collection of medical data | Nantes University Hospital | Non Traumatic Acute Brain Injury | 01/50 | 01/50 | | |
NCT02426255: Post Traumatic Critical Complications: a Prospective Cohort Study (ATLANREA) |
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| Recruiting | N/A | 5000 | Europe | Collection of medical data from ICU patients | Nantes University Hospital | Severe Trauma (With or Without Traumatic Brain Injury) | 01/50 | 01/50 | | |
| URBAN, Thierry |
| Recruiting | 2 | 550 | Europe | Durvalumab | UNICANCER, AstraZeneca | Small Cell Lung Carcinoma | 01/27 | 03/29 | | |
| Active, not recruiting | N/A | 413 | Europe | Quality of Life Questionnaire-Core 30 (QLQ-C30), Quality of Life Questionnaire-Lung Cancer 13 (QLQ-LC13), 5-level EuroQoL EQ5D (EQ5D-5L) | Groupe Francais De Pneumo-Cancerologie, AstraZeneca | Non-Small Cell Lung Cancer | 06/27 | 06/27 | | |
| Prunier, Fabrice |
| Recruiting | 3 | 340 | Europe, RoW | Vitamin K antagonist, Direct oral anticoagulant | Centre Hospitalier Universitaire de Nīmes | Intracardiac Thrombus, STEMI, Heart Failure | 04/25 | 04/25 | | |
| Piquilloud, Lise |
| Completed | N/A | 40 | Europe | ASV ventilation | University of Lausanne Hospitals | Mechanical Ventilation | 12/23 | 12/23 | | |
| PRIOU, Pascaline |
| Recruiting | 3 | 86 | Europe | bosentan, placebo | University Hospital, Grenoble | Ischemic Optic Neuropathy | 12/23 | 12/25 | | |
| Recruiting | N/A | 160 | Europe | SIMEOX | Physio-Assist, Icadom | Pulmonary Cystic Fibrosis | 12/24 | 06/25 | | |
DIAPASOM, NCT06457451: Impact of a Coordinated Dietetic-adapted Physical Activity Program on the Percentage of Lean Body Mass in Adults With Cystic Fibrosis Treated With Elexacaftor-Tezacaftor-Ivacaftor: Multicentre Randomised Controlled Trial |
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| Recruiting | N/A | 100 | Europe | DIAPASOM program | University Hospital, Tours, Fondation Ildys | Cystic Fibrosis | 11/27 | 11/27 | | |
| Trzepizur, Wojciech |
NCT05960175: Impact of Patient Involvement in Alerts Management of Telemonitoring CPAP |
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| Recruiting | N/A | 530 | Europe | New telemonitoring approach using 2 connected devices : Scanwatch connected watch + Asten&masanté application | Asten Sante, Slb Pharma, Nouvéal, Withings | OSA | 01/25 | 10/25 | | |
ORTAP, NCT05939934: Impact of the Mandibular Advancement Device on Sleep Apnea During CPAP Withdrawal |
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| Not yet recruiting | N/A | 40 | Europe | Mandibular advancement device treatment | University Hospital, Angers | Sleep Apnea, Obstructive, Endothelial Dysfunction | 11/25 | 11/25 | | |
| Recruiting | N/A | 300 | Europe | | University Hospital, Angers | Sleep Apnea, Obstructive | 02/26 | 02/26 | | |
| COUTANT, Régis |
| Recruiting | N/A | 70 | Europe | psychological evaluation | University Hospital, Angers, University of Angers, Angers | Turner Syndrome, Isolated Growth Hormone Deficiency, Cognitive Functions, Social Cognition, Pediatrics | 12/25 | 12/25 | | |
APATDIAGNOSIS, NCT06283797: Efficacy of Automated Insulin Therapy Early Initiated After Diagnosis on Blood Glucose Control in Children and Adolescents with Type 1 Diabetes |
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| Recruiting | N/A | 112 | Europe | OmniPod 5, Dexcom G6, PAID questionnaires | University Hospital, Montpellier, Hopital Universitaire Robert-Debre, University Hospital, Tours, University Hospital, Angers, University of Virginia | Diabetes | 06/26 | 06/27 | | |
| Not yet recruiting | N/A | 155 | Europe | Measure of Basal Copeptin level, Measure of arginine-stimulated copeptin, IRM, Water reduction at home | Assistance Publique Hopitaux De Marseille | Primary Polydipsia, Central Diabetes Insipidus, Nephrogenic Diabetes Insipidus | 03/28 | 05/28 | | |
| MARTIN, Ludovic |
| Not yet recruiting | N/A | 140 | Europe | Questionnaire on congenital birthmarks | University Hospital, Angers | Body Representation, Congenital Skin Disorder, Feelings | 11/23 | 06/24 | | |
| Recruiting | N/A | 99 | Europe | study treatment PPI, Placebo comparator | Centre Hospitalier Universitaire de Nice | Pseudoxanthoma Elasticum | 12/26 | 09/27 | | |
| Not yet recruiting | N/A | 650 | NA | Pseudoxanthoma Elasticum | University Hospital, Angers | Pseudoxanthoma Elasticum | 01/31 | 01/31 | | |
| Recruiting | N/A | 9000 | Europe | | University Hospital, Lille | Adnexal Tumor of Skin, Merkel Cell Carcinoma, Advanced Basal Cell Carcinoma Requiring Systemic Treatment | 12/25 | 12/25 | | |
NCT01034969: Firazyr® Patient Registry (Icatibant Outcome Survey - IOS) |
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| Completed | N/A | 1761 | Europe, RoW | | Shire, Takeda Development Center Americas, Inc. | Hereditary Angioedema (HAE) | 05/24 | 05/24 | | |
| ILLOUZ, Frédéric |
LENVOS, NCT03732495: Study of the Efficacy of Lenvatinib Combined With Denosumab in the Treatment of Patients With Predominant Bone Metastatic Radioiodine Refractory Differentiated Thyroid Carcinomas |
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| Recruiting | 2 | 35 | Europe | Lenvatinib + Denosumab | Centre Leon Berard | Thyroid Cancer Metastatic | 12/22 | 01/23 | | |
| RODIEN, Patrice |
| Active, not recruiting | 3 | 291 | Europe, Canada, Japan, US, RoW | Selpercatinib, LY3527723, LOXO-292, Cabozantinib, Vandetanib | Loxo Oncology, Inc., Eli Lilly and Company | Medullary Thyroid Cancer | 05/23 | 02/26 | | |
| Active, not recruiting | 3 | 154 | Europe, Canada, US, RoW | Veligrotug (VRDN-001) Phase 1/2 MAD (HV and TED), VRDN-001 Phase 3 Cohort (THRIVE), VRDN-001 Placebo | Viridian Therapeutics, Inc., Viridian Therapeutics, Inc. | Thyroid Eye Disease | 07/24 | 03/25 | | |
INTERMEDIATE, NCT04290663: Systematic Radioiodine Administration Versus Decision of Radioiodine Treatment Guided by a Post-operative Work-up |
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| Recruiting | 3 | 476 | Europe | Systematic RAI-treatment, Decision of RAI-treatment guided by a post-operative assessment | Centre Francois Baclesse, French cancer Institute INCa | Thyroid Cancer, Intermediate Risk | 02/31 | 02/33 | | |
LENVOS, NCT03732495: Study of the Efficacy of Lenvatinib Combined With Denosumab in the Treatment of Patients With Predominant Bone Metastatic Radioiodine Refractory Differentiated Thyroid Carcinomas |
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| Recruiting | 2 | 35 | Europe | Lenvatinib + Denosumab | Centre Leon Berard | Thyroid Cancer Metastatic | 12/22 | 01/23 | | |
| Recruiting | N/A | 2000 | Europe | | Institut National de la Santé Et de la Recherche Médicale, France | Silver Russell Syndrome, Beckwith-Wiedemann Syndrome, Transient Neonatal Diabetes Mellitus, Angelman Syndrome, Prader-Willi Syndrome, Temple Syndrome, Kagami-Ogata Syndrome, Pseudohypoparathyroidism, Familial Precocious Puberty | 03/32 | 03/32 | | |
| Podevin, Guillaume |
PedDiaVen, NCT04862494: Diaphragmatic Eventration in Children : Evaluation of Care Strategies and Results in the French Cohort. |
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| Not yet recruiting | N/A | 100 | NA | clinical surveillance, diaphragmatic plication | University Hospital, Angers | Diaphragmatic Eventration | 12/21 | 06/22 | | |
| Oberti, Frédéric |
ProPILARifax, NCT03069131: Two Strategies of Primary Prophylaxis of Spontaneous Bacterial Peritonitis in Severe Cirrhotic Patients With Ascites |
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| Completed | 3 | 160 | Europe | Rifaximin, Placebo | Centre Hospitalier Universitaire de Besancon, Alfasigma S.p.A., LC2 PHARMA | Cirrhosis, Ascites, Peritonitis | 06/22 | 03/23 | | |
AB-LATE02, NCT04727307: Neoadjuvant Atezo, Adjuvant Atezo + Beva Combined With RF Ablation of Small HCC: a Multicenter Randomized Phase II Trial |
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| Recruiting | 2 | 202 | Europe | Atezolizumab (neoadjuvant), Tecentriq, Percutaneous Radiofrequency, Bevacizumab (adjuvant), Avastin 400 mg in 16 ml Injection, Avastin 100 mg in 4 ml Injection, Atezolizumab (adjuvant) | University Hospital, Montpellier | Hepatocellular Carcinoma | 02/26 | 02/31 | | |
| Recruiting | 2 | 100 | Europe, US | TheraSphere Y-90 glass microsphere therapy, Durvalumab (Imfinzi) immunotherapy, Tremelimumab immunotherapy | Boston Scientific Corporation, Biocompatibles UK Ltd | Hepatocellular Carcinoma | 06/27 | 06/27 | | |
| Recruiting | 2 | 50 | Europe | Tislelizumab, BGB-A317 | UNICANCER, BeiGene Switzerland GmbH | Hepatocellular Carcinoma by BCLC Stage | 11/27 | 04/28 | | |
ARIAPUMP, NCT03506893: Medical-economic Evaluation of the Care of Refractory Ascites by Implantation of Alfapump® Device in Cirrhotic Patients |
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| Recruiting | N/A | 90 | Europe | Alphapump, Ascites puncture | University Hospital, Grenoble | Ascites, Paracentesis, Cirrhosis | 12/22 | 12/25 | | |
| Completed | N/A | 104 | Europe | Transjugular Portosytemic Shunt (TIPS), glue obliteration | Centre Hospitalier Universitaire de Besancon | Bleeding Gastric Varices, Cirrhosis | 03/23 | 02/24 | | |
| GOHIER, Philippe |
| Recruiting | 3 | 86 | Europe | bosentan, placebo | University Hospital, Grenoble | Ischemic Optic Neuropathy | 12/23 | 12/25 | | |
| VENARA, Aurélien |
| Not yet recruiting | N/A | 540 | NA | collection of data | University Hospital, Angers | Obstetric Trauma, Anal Sphincter Injury, Anal Incontinence | 06/22 | 07/22 | | |
| Recruiting | N/A | 100 | Europe | ultrasonography | University Hospital, Angers | Postoperative Ileus | 08/22 | 09/22 | | |
| Completed | N/A | 50 | Europe | Enhanced recovery program | University Hospital, Angers | Small Bowel Obstruction, Surgery | 11/22 | 12/22 | | |
GRECCAR-9, NCT02841293: Cost-utility of Two Strategies of Perineal Reconstruction After Abdominoperineal Resection for Anorectal Carcinoma |
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| Recruiting | N/A | 140 | Europe | Biological mesh, Primary perineal wound closure | University Hospital, Toulouse | Abdominoperineal Resection | 02/24 | 02/24 | | |
RADIOLIGA, NCT06170736: Radiofrequency Ablation vs Doppler-guided Haemorrhoidal Artery Ligation in the Treatment of Haemorrhoidal Disease |
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| Recruiting | N/A | 168 | Europe | Doppler-Guided Haemorrhoidal Artery Ligation, Radiofrequency ablation | Centre Hospitalier Departemental Vendee | Haemorrhoids, Internal Haemorrhoids, Grade II/III Haemorrhoids | 01/26 | 09/28 | | |
Colo-SENSIUM, NCT05610995: Feasibility Study of Early Return-home After Colorectal Surgery Using a SENSIUM® Vital Parameter Monitoring Device |
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| Recruiting | N/A | 88 | Europe | SENSIUM Patch | University Hospital, Grenoble | Premature Exit After Colorectal Surgery | 06/24 | 12/24 | | |
FLATQUAL, NCT06675097: Assessment of the Impact of Intestinal Gas Emission Quality on the Postoperative Course After Abdominal Surgery |
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| Not yet recruiting | N/A | 200 | Europe | | University Hospital, Angers | Postoperative Complication, Recovery, Physiological | 02/26 | 10/26 | | |
PILO, NCT06378918: Comparison of the Effectiveness of the Simple Puncture Compared to the Incision of an Abscess on the PiLOnidal Sinus |
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| Not yet recruiting | N/A | 134 | Europe | puncture, aspiration, incision of the abscess, gold standard | University Hospital, Angers | Pilonidal Cyst | 09/25 | 09/27 | | |
| Recruiting | N/A | 630 | Europe | Standard support, Early surgery proposed according to the radiological score | University Hospital, Angers, Direction Générale de l'Offre de Soins | Small Bowel Obstruction | 01/27 | 01/28 | | |
| Gascoin, Géraldine |
| Recruiting | N/A | 200 | Europe | questionary, Daily continuous recording of radiofrequency exposure levels, Follow-up of daily infants clinical parameters, recording of cerebral (EEG), autonomic nervous (ECG) activity | Centre Hospitalier Universitaire, Amiens, University Hospital, Brest, CHU LYON, University Hospital, Strasbourg, France, University Hospital, Toulouse | Preterm Newborn | 09/26 | 10/26 | | |
PoPPY, NCT04827225: Assessment of the Mental State of Parents of Premature Children and Impact on Neurodevelopment of the Child |
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| Recruiting | N/A | 300 | Europe | questionnaires | University Hospital, Angers | Parent-Child Relations | 04/24 | 08/26 | | |
