Sarcoma
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  • ||||||||||  cyclophosphamide / Generic mfg.
    Trial completion, Metastases:  Clinical Study of Metronomic Oral Cyclophosphamide in Patients With Advanced Sarcomas (clinicaltrials.gov) -  Mar 29, 2017   
    P2,  N=24, Completed, 
    SR is the more cost-effective brachytherapy approach in the treatment of STS, and should be considered as healthcare transitions into value-based medicine. Recruiting --> Completed
  • ||||||||||  Avastin (bevacizumab) / Roche
    Trial initiation date:  Optune (clinicaltrials.gov) -  Mar 29, 2017   
    P2,  N=85, Not yet recruiting, 
    The patient experienced a rapid, radiographic response, demonstrating the potential for LOXO-101 to provide benefit for IFS harboring NTRK gene fusions. Initiation date: Oct 2016 --> Apr 2017
  • ||||||||||  sunitinib / Generic mfg., Cabometyx (cabozantinib tablet) / Exelixis, Ipsen
    Enrollment open, Trial initiation date, Trial primary completion date, Stroma:  Ph II CABOGIST in GIST (clinicaltrials.gov) -  Mar 28, 2017   
    P2,  N=50, Recruiting, 
    Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting | Initiation date: May 2016 --> Feb 2017 | Trial primary completion date: Jan 2017 --> Aug 2019
  • ||||||||||  Trial primary completion date:  A Study of Lymphoseek (clinicaltrials.gov) -  Mar 24, 2017   
    P2,  N=32, Recruiting, 
    Active, not recruiting --> Completed Trial primary completion date: Dec 2020 --> Sep 2017
  • ||||||||||  Stivarga (regorafenib) / Bayer, sunitinib / Generic mfg.
    Enrollment closed, Trial primary completion date, Stroma, Metastases:  Phase Ib Study of SUnitinib Alternating With REgorafenib in Patients With Metastatic and/or Unresectable GIST (clinicaltrials.gov) -  Mar 23, 2017   
    P1,  N=35, Active, not recruiting, 
    The authors recommend an individualized approach with careful multidisciplinary decision making, and the patient should be informed about the morbidity of en bloc surgery when considering MPNST resection. Recruiting --> Active, not recruiting | Trial primary completion date: Aug 2017 --> Dec 2016
  • ||||||||||  Mepact (mifamurtide) / Takeda
    Trial completion, Trial primary completion date, Metastases:  A Eurosarc Study of Mifamurtide in Advanced Osteosarcoma (MEMOS) (clinicaltrials.gov) -  Mar 22, 2017   
    P2,  N=8, Completed, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Aug 2017 --> Dec 2016 Active, not recruiting --> Completed | Trial primary completion date: Apr 2017 --> Nov 2016
  • ||||||||||  Enrollment open:  Smartphone Confocal Microscopy for Diagnosing Kaposi's Sarcoma (clinicaltrials.gov) -  Mar 22, 2017   
    P=N/A,  N=500, Recruiting, 
    Active, not recruiting --> Completed | Trial primary completion date: Apr 2017 --> Nov 2016 Not yet recruiting --> Recruiting
  • ||||||||||  Trial completion, Trial primary completion date:  Combination Chemotherapy in Treating Patients With Sarcoma (clinicaltrials.gov) -  Mar 22, 2017   
    P=N/A,  N=120, Completed, 
    Not yet recruiting --> Recruiting Active, not recruiting --> Completed | Trial primary completion date: Sep 2015 --> Oct 2013
  • ||||||||||  Trial primary completion date:  A Study of Lymphoseek (clinicaltrials.gov) -  Mar 22, 2017   
    P2,  N=32, Recruiting, 
    Active, not recruiting --> Completed Trial primary completion date: Jul 2018 --> Dec 2020
  • ||||||||||  Yondelis (trabectedin) / Otsuka, PharmaMar, Valeo Pharma, J&J
    Trial primary completion date, Metastases:  TAUL: Activity of Trabectedin or Gemcitabine + Docetaxel in Uterine Leiomyosarcoma (clinicaltrials.gov) -  Mar 22, 2017   
    P2,  N=168, Active, not recruiting, 
    Trial primary completion date: Jul 2018 --> Dec 2020 Trial primary completion date: Sep 2016 --> Jul 2017
  • ||||||||||  linsitinib (ASP7487) / Sling Therap
    Trial completion, Trial primary completion date, Metastases:  LINES: Eurosarc Trial of Linsitinib in Advanced Ewing Sarcoma (clinicaltrials.gov) -  Mar 22, 2017   
    P2,  N=40, Completed, 
    Trial primary completion date: Sep 2016 --> Jul 2017 Active, not recruiting --> Completed | Trial primary completion date: Nov 2016 --> Jul 2016
  • ||||||||||  Journal:  Management of desmoplastic small round cell tumor. (Pubmed Central) -  Mar 19, 2017   
    With this challenging disease, multidisciplinary therapy, including aggressive surgery, is warranted. This review will address DSRCT biology and treatment options and discuss outcomes.
  • ||||||||||  timolol oral / Generic mfg.
    Journal:  Myeloid Sarcoma in the Orbit. (Pubmed Central) -  Mar 17, 2017   
    [J Pediatr Ophthalmol Strabismus. 2016;53:e64-e68.].
  • ||||||||||  Leukine (sargramostim) / Partner Therap, Unituxin (dinutuximab) / United Therapeutics Corp, Ohara Pharma
    Combination therapy:  Dinutuximab in Combination With Sargramostim in Treating Patients With Recurrent Osteosarcoma (clinicaltrials.gov) -  Mar 14, 2017   
    P2,  N=44, Suspended, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Mar 2017 --> Jan 2018 Recruiting --> Suspended