Sarcoma MOAs - LARVOL Sigma

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Phase N/A 1 2 3 4 Products	0	18	36	54	72	90	108	126	144	162	180



CD20 inhib




VEGFR inhib




Alkylating agent




CD20 inhib




CTLA4 inhib




mTORC2 inhib




VEGF-A inhib




DNA inhib




PD1 inhib




Tubulin inhib




HDAC2 inhib




c-KIT inhib




PDGFR β inhib




FGFR3 inhib




TIE-2 inhib




HER2 inhib




IL-11 stim




EGFR inhib




Progesterone receptor antag




DNA PK inhib




PI3K inhib




AKT inhib




Apoptosis stim




CDK6 inhib




PARP3 inhib




PIGF inhib




GCR agon




Hedgehog cell-signalling pathway inhib




TLR8 agon




Bcl2 inhib




Bcl2 inhib




Cell death stim




Estrogen receptor antag




HSP90 inhib




IGF-1R inhib




MDM2 inhib




mTOR inhib




BRAF inhib




Dendritic cell activator




IL-2 stim




JAK1 inhib




Serotonin uptake inhib




TNFα inhib




Trk receptor antag




CCR5 receptor antag




Factor X inhib




GM-CSF agon




SMO protein inhib




TRAIL R2 inhib




Apoptosis inhib



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