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94 Companies |
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165 Products |
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165 Products |
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42 Mechanisms of Action |
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2 Trials |
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1453 News |
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- pravastatin / Generic mfg.
Trial primary completion date: OxLDL: Lipid Lowering Agents to Limit Lipid Oxidation and Activation of Clotting System in Nephrotic Syndrome (clinicaltrials.gov) - Mar 8, 2016
P1, N=10, Recruiting, Sponsor: University of North Carolina, Chapel Hill
Trial primary completion date: Dec 2015 --> Dec 2016
- Enrollment closed: WALDI: The Metabolic Effect of Walnuts in Healthy Subjects (clinicaltrials.gov) - Mar 8, 2016
P=N/A, N=180, Active, not recruiting, Sponsor: Ludwig-Maximilians - University of Munich
Trial primary completion date: Dec 2015 --> Dec 2016 Recruiting --> Active, not recruiting
- Trial completion: Comparisons of Two Low-density Lipoprotein Apheresis Systems in Patients With Homozygous Familial Hypercholesterolemia (clinicaltrials.gov) - Mar 8, 2016
P=N/A, N=9, Completed, Sponsor: Laval University
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- ||||||| Galafold (migalastat) / Amicus
Trial completion, Trial primary completion date, Monotherapy: Open-Label Phase 3 Long-Term Safety Study of Migalastat (clinicaltrials.gov) - Mar 1, 2016
P3, N=85, Completed, Sponsor: Amicus Therapeutics
Active, not recruiting --> Completed Active, not recruiting --> Completed | Trial primary completion date: Jul 2016 --> Feb 2016
- | Trial completion: Human Lipoprotein Pathophysiology - Subproject: Genetics of Familial Combined Hyperlipidemia (clinicaltrials.gov) - Feb 27, 2016
P=N/A, N=450, Completed, Sponsor: University of Washington
Active, not recruiting --> Completed | Trial primary completion date: Jul 2016 --> Feb 2016 No longer recruiting --> Completed
- Trial completion: Effect of Age on Glucose and Lipid Metabolism (clinicaltrials.gov) - Feb 21, 2016
P=N/A, N=44, Completed, Sponsor: The University of Texas Health Science Center at San Antonio
No longer recruiting --> Completed Active, not recruiting --> Completed
- | Trial completion: Postprandial Lipemia and Endothelial Function in ACCORD- Ancillary to ACCORD (clinicaltrials.gov) - Feb 16, 2016
P=N/A, N=0, Completed, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Active, not recruiting --> Completed No longer recruiting --> Completed
- Biomarker, Trial primary completion date: Serum Lipid Levels and Other Biomarkers of Cardiovascular Disease in Patients With Psoriasis (clinicaltrials.gov) - Feb 11, 2016
P=N/A, N=200, Recruiting, Sponsor: George Washington University
No longer recruiting --> Completed Trial primary completion date: Nov 2015 --> Mar 2016
- omega-3 ethylester concentrate / Generic mfg.
Enrollment change, Monotherapy: Effects of Lovaza on High Density Lipoprotein (HDL) Composition and Function in Hypertriglyceridemia (clinicaltrials.gov) - Feb 9, 2016
P4, N=0, Withdrawn, Sponsor: University of Utah
Trial primary completion date: Nov 2015 --> Mar 2016 N=26 --> 0
- Biomarker, Enrollment closed: Replacement of Saturated Fat in Dairy on Total Cholesterol (clinicaltrials.gov) - Feb 3, 2016
P=N/A, N=54, Active, not recruiting, Sponsor: University of Reading
N=26 --> 0 Recruiting --> Active, not recruiting
- | Trial completion, HEOR: The Health Outcomes Management and Evaluation (HOME) Study (clinicaltrials.gov) - Feb 3, 2016
P3, N=400, Completed, Sponsor: Emory University
Recruiting --> Active, not recruiting Active, not recruiting --> Completed
- |||| trigonellinamide (TRIA-662) / Cortria
Trial completion: A Pilot Study to Evaluate the Lipid Effects of TRIA-662 (clinicaltrials.gov) - Jan 28, 2016
P2, N=71, Completed, Sponsor: Cortria Corporation
Active, not recruiting --> Completed Active, not recruiting --> Completed
- ||| evacetrapib (LY2484595) / Eli Lilly
Trial completion: A Study of Evacetrapib in Participants With Abnormal Cholesterol (clinicaltrials.gov) - Jan 26, 2016
P1, N=101, Completed, Sponsor: Eli Lilly and Company
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Enrollment change: Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders (clinicaltrials.gov) - Jan 25, 2016
P2, N=46, Active, not recruiting, Sponsor: Masonic Cancer Center, University of Minnesota
Active, not recruiting --> Completed N=66 --> 46
- ||| Trial completion, Adherence: Improving Adherence to Statins Among Minority Populations (clinicaltrials.gov) - Jan 25, 2016
P=N/A, N=779, Completed, Sponsor: University of Miami
N=66 --> 46 Active, not recruiting --> Completed
- simvastatin / Generic mfg., lovastatin / Generic mfg., atorvastatin / Generic mfg.
Enrollment change, Trial withdrawal: Genetic Influence on Statin Pharmacodynamics (clinicaltrials.gov) - Jan 20, 2016
P=N/A, N=0, Withdrawn, Sponsor: Ohio State University
Active, not recruiting --> Completed N=200 --> 0 | Recruiting --> Withdrawn
- Trial primary completion date: Fabry Screening Study (clinicaltrials.gov) - Jan 18, 2016
P=N/A, N=5000, Suspended, Sponsor: Baylor Research Institute
N=200 --> 0 | Recruiting --> Withdrawn Trial primary completion date: Dec 2015 --> Dec 2018
- Trial completion, Enrollment change: Androgenetic Alopecia in Fabry Disease (clinicaltrials.gov) - Jan 15, 2016
P=N/A, N=107, Completed, Sponsor: Baylor Research Institute
Trial primary completion date: Dec 2015 --> Dec 2018 Recruiting --> Completed | N=240 --> 107
- Myalept (metreleptin) / Novelion
Clinical protocol, Enrollment closed, Trial primary completion date: Clinical Protocol to Investigate the Efficacy of Recombinant Human Leptin (Metreleptin) in Nonalcoholic Steatohepatitis (NASH) or Nonalcoholic Fatty Liver Disease (NAFLD) Associated With Lipodystrophy (clinicaltrials.gov) - Jan 11, 2016
P2, N=23, Active, not recruiting, Sponsor: University of Michigan
Recruiting --> Completed | N=240 --> 107 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2015 --> May 2016
- simvastatin / Generic mfg.
Phase classification: Evaluation of the Effects of Simvastatin 40mg (clinicaltrials.gov) - Jan 7, 2016
P4, N=20, Completed, Sponsor: Cardinal Tien Hospital
Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2015 --> May 2016 Phase classification: P3 --> P4
- Trial completion: Effect of Different Types of Carbohydrates Consumed After Exercise on Blood Fat Levels (clinicaltrials.gov) - Jan 6, 2016
P=N/A, N=23, Completed, Sponsor: University of Saskatchewan
Phase classification: P3 --> P4 Active, not recruiting --> Completed
- Trial completion, HEOR: U of A/ U of M Beans and Peas Health Claim Project (clinicaltrials.gov) - Dec 25, 2015
P1/2, N=180, Completed, Sponsor: University of Alberta
Active, not recruiting --> Completed Recruiting --> Completed
- Trial completion, Trial primary completion date, Adherence: Pilot Program to Improve Statin Adherence and Lower Cholesterol in Older Adults (clinicaltrials.gov) - Dec 23, 2015
P1/2, N=43, Completed, Sponsor: University of Missouri-Columbia
Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2011 --> Dec 2013
- Trial completion, Enrollment change, Trial primary completion date, Adherence: The Effect of Synching Prescription Refills on Adherence (clinicaltrials.gov) - Dec 23, 2015
P=N/A, N=691, Completed, Sponsor: University of Pennsylvania
Recruiting --> Completed | Trial primary completion date: Dec 2011 --> Dec 2013 Active, not recruiting --> Completed | N=976 --> 691 | Trial primary completion date: Jan 2015 --> Nov 2015
- | Trial completion: Short-term Behavioral Effects of Cholesterol Therapy in Smith-Lemli-Opitz Syndrome (clinicaltrials.gov) - Dec 22, 2015
P2, N=13, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Active, not recruiting --> Completed | N=976 --> 691 | Trial primary completion date: Jan 2015 --> Nov 2015 Recruiting --> Completed
- ||| Leqvio (inclisiran) / Alnylam, Novartis
Trial completion: A Phase 1 Study of an Investigational Drug, ALN-PCSSC, in Subjects With Elevated Low Density Lipoprotein Cholesterol (LDL-C) (clinicaltrials.gov) - Dec 17, 2015
P1, N=70, Completed, Sponsor: Alnylam Pharmaceuticals
Recruiting --> Completed Active, not recruiting --> Completed
- Enrollment closed: HCIT-MLD: Imaging Study of the White Matter Lesions in Children With Metachromatic Leucodystrophy (clinicaltrials.gov) - Dec 16, 2015
P=N/A, N=29, Active, not recruiting, Sponsor: Assistance Publique - H
Active, not recruiting --> Completed Recruiting --> Active, not recruiting
- ||| Trial completion: CEPHEUSII: CEntralized Pan-Russian Survey of tHE Undertreatment of hypercholeSterolemia II (CEPHEUS II) (clinicaltrials.gov) - Dec 16, 2015
P=N/A, N=2700, Completed, Sponsor: AstraZeneca
Recruiting --> Active, not recruiting Recruiting --> Completed
- Trial termination: Collection of Cerebrospinal Fluid in Healthy Children (clinicaltrials.gov) - Dec 12, 2015
P=N/A, N=32, Terminated, Sponsor: Weill Medical College of Cornell University
Recruiting --> Completed Enrolling by invitation --> Terminated; Study interest shifted
- ||||||| bococizumab (RN316) / Pfizer
Trial completion, Enrollment change: SPIRE-SI: Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects Who Are Intolerant to Statins (clinicaltrials.gov) - Dec 12, 2015
P3, N=184, Completed, Sponsor: Pfizer
Enrolling by invitation --> Terminated; Study interest shifted Active, not recruiting --> Completed | N=150 --> 184
- |||| Kynamro (mipomersen) / Kastle Therap
Trial primary completion date: FOCUS FH: A Study of the Safety and Efficacy of Two Different Regimens of Mipomersen in Patients With Familial Hypercholesterolemia and Inadequately Controlled Low-Density Lipoprotein Cholesterol (clinicaltrials.gov) - Dec 12, 2015
P3, N=300, Active, not recruiting, Sponsor: Genzyme, a Sanofi Company
Active, not recruiting --> Completed | N=150 --> 184 Trial primary completion date: Feb 2015 --> Feb 2016
- ||||||| Cerdelga (eliglustat tartrate) / Sanofi
Trial completion: A Study of Eliglustat Tartrate (Genz-112638) in Patients With Gaucher Disease to Evaluate Once Daily Versus Twice Daily Dosing (EDGE) (clinicaltrials.gov) - Dec 12, 2015
P3, N=171, Completed, Sponsor: Genzyme, a Sanofi Company
Trial primary completion date: Feb 2015 --> Feb 2016 Active, not recruiting --> Completed
- pegunigalsidase alfa (PRX-102) / Protalix, Chiesi
Trial primary completion date: An Extension of a Phase 1/2, Open Label, Dose Ranging Study of PRX-102 in Adult Fabry Patients (clinicaltrials.gov) - Dec 10, 2015
P1/2, N=18, Enrolling by invitation, Sponsor: Protalix
Active, not recruiting --> Completed Trial primary completion date: Jul 2015 --> Dec 2016
- ||| Enrollment change: Portfolio 5 - Multicentre Dietary Advice on Serum Lipids in Hyperlipidemia (clinicaltrials.gov) - Dec 7, 2015
P2, N=351, Active, not recruiting, Sponsor: University of Toronto
Trial primary completion date: Jul 2015 --> Dec 2016 N=220 --> 351
- Trial completion, Trial primary completion date: Trial of Leptin Replacement Therapy in Patients With Lipodystrophy (clinicaltrials.gov) - Dec 7, 2015
P2/3, N=24, Completed, Sponsor: University of Texas Southwestern Medical Center
N=220 --> 351 Active, not recruiting --> Completed | Trial primary completion date: Jul 2011 --> Nov 2014
- Enrollment closed: HeartHealth: Improving Heart Health in Appalachia (clinicaltrials.gov) - Dec 6, 2015
P=N/A, N=330, Active, not recruiting, Sponsor: Debra Moser
Active, not recruiting --> Completed | Trial primary completion date: Jul 2011 --> Nov 2014 Not yet recruiting --> Active, not recruiting
- || Trial primary completion date: The Impact of Artichoke Leaf Extract on Blood Cholesterol: Primary Study (clinicaltrials.gov) - Dec 4, 2015
P=N/A, N=90, Recruiting, Sponsor: University of Mississippi Medical Center
Not yet recruiting --> Active, not recruiting Trial primary completion date: Jul 2015 --> Jul 2017
- | Biomarker, Trial completion: Pharmacogenetics of Hypertriglyceridemia in Hispanics (clinicaltrials.gov) - Dec 3, 2015
P=N/A, N=274, Completed, Sponsor: University of California, Los Angeles
Trial primary completion date: Jul 2015 --> Jul 2017 No longer recruiting --> Completed
- Trial primary completion date: Effects of Almond Intake on Atherogenic Lipoprotein Particles (clinicaltrials.gov) - Nov 28, 2015
P=N/A, N=40, Recruiting, Sponsor: Children's Hospital & Research Center Oakland
No longer recruiting --> Completed Trial primary completion date: Dec 2015 --> Jun 2016
- Trial completion, Enrollment change: Prioritized Clinical Decision Support (CDS) to Reduce Cardiovascular Risk (clinicaltrials.gov) - Nov 27, 2015
P=N/A, N=29950, Completed, Sponsor: HealthPartners Institute
Trial primary completion date: Dec 2015 --> Jun 2016 Active, not recruiting --> Completed | N=60 --> 29950
- ZY T1 / Zydus Lifesci
Enrollment change, Trial termination, Trial primary completion date: A Clinical Study to Evaluate the Safety,Tolerability and PK of ZYT1, Following Oral Administration in Healthy Volunteers (clinicaltrials.gov) - Nov 24, 2015
P1, N=24, Terminated, Sponsor: Cadila Healthcare Limited
Active, not recruiting --> Completed | N=60 --> 29950 N=112 --> 24 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2014 --> Jul 2012; Safety concerns
- |||| bococizumab (RN316) / Pfizer
Trial primary completion date: SPIRE-SI: Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects Who Are Intolerant to Statins (clinicaltrials.gov) - Nov 16, 2015
P3, N=150, Active, not recruiting, Sponsor: Pfizer
N=112 --> 24 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2014 --> Jul 2012; Safety concerns Trial primary completion date: Feb 2015 --> Nov 2015
- Trial primary completion date, Adherence: Is a Smartphone Application Effective as an Oral Medication Adherence Aid (clinicaltrials.gov) - Nov 15, 2015
P0, N=228, Recruiting, Sponsor: University of Arkansas
Trial primary completion date: Feb 2015 --> Nov 2015 Trial primary completion date: Oct 2015 --> Oct 2016
- Trial completion: VEDROP: Study of the Absorption of Vitamin E Water-soluble Form (Pegylated) in the Familial Hypocholesterolemia With Chylomicron Retention (clinicaltrials.gov) - Nov 15, 2015
P3, N=14, Completed, Sponsor: Hospices Civils de Lyon
Trial primary completion date: Oct 2015 --> Oct 2016 Active, not recruiting --> Completed
- | Trial completion, Enrollment change, Trial primary completion date: Effect Of Capros Supplementation On Cardiovascular Disease Risk Factors In Humans (clinicaltrials.gov) - Nov 12, 2015
P=N/A, N=24, Completed, Sponsor: Chandan K Sen
Active, not recruiting --> Completed Active, not recruiting --> Completed | N=30 --> 24 | Trial primary completion date: Dec 2015 --> Jan 2015
- |||||| bococizumab (RN316) / Pfizer
Enrollment open: SPIRE-LDL: Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Hyperlipidemia or Mixed Dyslipidemia at Risk of Cardiovascular Events (clinicaltrials.gov) - Nov 5, 2015
P3, N=1932, Recruiting, Sponsor: Pfizer
Active, not recruiting --> Completed | N=30 --> 24 | Trial primary completion date: Dec 2015 --> Jan 2015 Active, not recruiting --> Recruiting
- |||| bococizumab (RN316) / Pfizer
Trial primary completion date: SPIRE-SI: Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects Who Are Intolerant to Statins (clinicaltrials.gov) - Nov 5, 2015
P3, N=150, Active, not recruiting, Sponsor: Pfizer
Active, not recruiting --> Recruiting Trial primary completion date: Nov 2015 --> Feb 2015
- |||||| bococizumab (RN316) / Pfizer
Enrollment open: SPIRE-LL: Randomized Clinical Trial of Bococizumab (PF-04950615; RN316) in Subjects With Primary Hyperlipidemia or Mixed Dyslipidemia At Risk Of Cardiovascular Events (clinicaltrials.gov) - Nov 5, 2015
P3, N=690, Recruiting, Sponsor: Pfizer
Trial primary completion date: Nov 2015 --> Feb 2015 Active, not recruiting --> Recruiting
- || evacetrapib (LY2484595) / Eli Lilly
Enrollment closed: A Study of Evacetrapib in Participants With Abnormal Cholesterol (clinicaltrials.gov) - Nov 5, 2015
P1, N=101, Active, not recruiting, Sponsor: Eli Lilly and Company
Active, not recruiting --> Recruiting Recruiting --> Active, not recruiting
- ||| Benecol (sitostanol ester) / J&J
Trial completion: Lipid-lowering Effect of a Plant Stanol Ester Supplement Product (clinicaltrials.gov) - Oct 29, 2015
P=N/A, N=103, Completed, Sponsor: Raisio Group
Recruiting --> Active, not recruiting Active, not recruiting --> Completed