Sphingolipidoses
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 94 Companies   165 Products   165 Products   42 Mechanisms of Action   2 Trials   1453 News 


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  • ||||||||||  Goofice (elobixibat) / Eisai, Mochida, Ipsen
    Phase classification:  Study of A3309 in Patients With Dyslipidemia (clinicaltrials.gov) -  Mar 7, 2024   
    P2,  N=36, Completed, 
    Phase classification: P1/2 --> P=N/A Phase classification: P2a --> P2
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date:  Stress and Sugar Synergy (clinicaltrials.gov) -  Jan 16, 2019   
    P=N/A,  N=23, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Aug 2014 --> Jan 2018 Active, not recruiting --> Completed | Trial completion date: Dec 2018 --> Dec 2016 | Trial primary completion date: Dec 2018 --> Dec 2016
  • ||||||||||  Trial completion:  Cholic Acid for Hepatic Steatosis in Lipodystrophy (clinicaltrials.gov) -  Jan 16, 2019   
    P2,  N=18, Completed, 
    Active, not recruiting --> Completed | Trial completion date: Dec 2018 --> Dec 2016 | Trial primary completion date: Dec 2018 --> Dec 2016 Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Trial primary completion date:  The CREATE Wellness Study (clinicaltrials.gov) -  Oct 16, 2018   
    P=N/A,  N=647, Completed, 
    Phase classification: P1 --> P1/2 Active, not recruiting --> Completed | Trial primary completion date: Jun 2018 --> Sep 2018
  • ||||||||||  Trial completion, Phase classification, Enrollment change:  Novel Therapies for Metabolic Complications of Lipodystrophies (clinicaltrials.gov) -  Oct 16, 2018   
    P=N/A,  N=4, Completed, 
    Active, not recruiting --> Completed | Trial primary completion date: Jun 2018 --> Sep 2018 Recruiting --> Completed | Phase classification: P2/3 --> PN/A | N=72 --> 4
  • ||||||||||  Trial completion, Phase classification:  Portfolio 5 - Multicentre Dietary Advice on Serum Lipids in Hyperlipidemia (clinicaltrials.gov) -  Oct 16, 2018   
    P=N/A,  N=351, Completed, 
    Recruiting --> Completed | Phase classification: P2/3 --> PN/A | N=72 --> 4 Active, not recruiting --> Completed | Phase classification: P2 --> PN/A
  • ||||||||||  Enrollment change, Trial completion date, Trial primary completion date:  Low Carbohydrate Diet - Effect on Plasma Lipids and Metabolic Markers (clinicaltrials.gov) -  Oct 10, 2018   
    P=N/A,  N=30, Completed, 
    Active, not recruiting --> Completed | Phase classification: P2 --> PN/A N=22 --> 30 | Trial completion date: Nov 2013 --> Sep 2017 | Trial primary completion date: Nov 2013 --> Sep 2017
  • ||||||||||  Galafold (migalastat) / Amicus
    Trial termination, Monotherapy:  Open-Label Phase 3 Long-Term Safety Study of Migalastat (clinicaltrials.gov) -  Oct 2, 2018   
    P3,  N=85, Terminated, 
    Completed --> Terminated; The Sponsor (Amicus Therapeutics) terminated this study for logistical reasons. Completed --> Terminated; Amicus Therapeutics discontinued Study AT1001-041 for logistical reasons.
  • ||||||||||  fenofibrate nanoparticle formulation / Generic mfg.
    Trial completion, Trial completion date, Trial primary completion date, Combination therapy, Monotherapy:  Phase III Study of Rosuvastatin and Fenofibrate Versus Rosuvastatin in Mixed Dyslipidemia (clinicaltrials.gov) -  Aug 24, 2018   
    P3,  N=362, Completed, 
    N=14 --> 9 Not yet recruiting --> Completed | Trial completion date: Mar 2016 --> Jun 2017 | Trial primary completion date: Mar 2016 --> Oct 2016
  • ||||||||||  Trial completion, Enrollment change:  Prolongation of Pregnancy in Preeclampsia by Therapeutic Lipid Apheresis (clinicaltrials.gov) -  Aug 9, 2018   
    P=N/A,  N=6, Completed, 
    Not yet recruiting --> Completed | Trial completion date: Mar 2016 --> Jun 2017 | Trial primary completion date: Mar 2016 --> Oct 2016 Recruiting --> Completed | N=15 --> 6
  • ||||||||||  Livalo (pitavastatin) / Kowa, Eli Lilly
    Trial completion, Trial completion date, Trial initiation date, Trial primary completion date:  SIPHON: to Evaluate the Safety and Efficacy of Pitavastatin in Patients With IFG and Hyperlipidemia (clinicaltrials.gov) -  Mar 8, 2018   
    P4,  N=313, Completed, 
    Active, not recruiting --> Completed Active, not recruiting --> Completed | Trial completion date: Oct 2017 --> May 2017 | Initiation date: Jan 2014 --> Sep 2013 | Trial primary completion date: May 2016 --> May 2017
  • ||||||||||  Trial completion date:  Detecting Dopaminergic Deficits in Individuals At-risk for Parkinsonism (clinicaltrials.gov) -  Mar 3, 2018   
    P=N/A,  N=60, Active, not recruiting, 
    Active, not recruiting --> Completed | Trial completion date: Oct 2017 --> May 2017 | Initiation date: Jan 2014 --> Sep 2013 | Trial primary completion date: May 2016 --> May 2017 Trial completion date: Dec 2017 --> Dec 2018
  • ||||||||||  Trial completion, Enrollment change, Trial completion date, Trial initiation date, Trial primary completion date:  Fabry Screening Study (clinicaltrials.gov) -  Feb 13, 2018   
    P=N/A,  N=2724, Completed, 
    Trial primary completion date: Dec 2017 --> Jun 2017 Suspended --> Completed | N=5000 --> 2724 | Initiation date: Aug 2008 --> Jan 2009 | Trial primary completion date: Dec 2018 --> Apr 2013 | Trial completion date: Jan 2019 --> Dec 2017
  • ||||||||||  Trial completion:  Allogeneic Bone Marrow Transplant for Inherited Metabolic Disorders (clinicaltrials.gov) -  Feb 5, 2018   
    P2,  N=46, Completed, 
    Recruiting --> Active, not recruiting | Trial completion date: Dec 2017 --> Sep 2018 Active, not recruiting --> Completed
  • ||||||||||  atorvastatin / Generic mfg.
    Trial completion, Trial primary completion date:  HDL PROTECT: The HDL Particle Protection Study (clinicaltrials.gov) -  Feb 1, 2018   
    P4,  N=16, Completed, 
    Active, not recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2014 --> May 2017
  • ||||||||||  pegunigalsidase alfa (PRX-102) / Protalix, Chiesi
    Trial completion, Trial primary completion date:  An Extension of a Phase 1/2, Open Label, Dose Ranging Study of PRX-102 in Adult Fabry Patients (clinicaltrials.gov) -  Jan 11, 2018   
    P1/2,  N=18, Completed, 
    Recruiting --> Completed | Trial primary completion date: Dec 2014 --> May 2017 Enrolling by invitation --> Completed | Trial primary completion date: Dec 2016 --> Mar 2016
  • ||||||||||  Enrollment closed, Trial primary completion date:  The CREATE Wellness Study (clinicaltrials.gov) -  Jan 8, 2018   
    P=N/A,  N=588, Active, not recruiting, 
    Active, not recruiting --> Completed Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2017 --> Jun 2018
  • ||||||||||  Trial completion, Enrollment change:  Screening for Fabry Disease in a Pediatric Population at Risk (clinicaltrials.gov) -  Dec 13, 2017   
    P=N/A,  N=1422, Completed, 
    Recruiting --> Active, not recruiting | Trial primary completion date: Dec 2017 --> Jun 2018 Active, not recruiting --> Completed | N=2000 --> 1422
  • ||||||||||  Enrollment change, Trial termination, Adherence:  Is a Smartphone Application Effective as an Oral Medication Adherence Aid (clinicaltrials.gov) -  Nov 20, 2017   
    P1,  N=68, Terminated, 
    Trial primary completion date: Aug 2018 --> Feb 2018 N=228 --> 68 | Recruiting --> Terminated; Study had a minor contingency that could not be resolved with the IRB.
  • ||||||||||  Trial completion:  Soda and Milk Study (clinicaltrials.gov) -  Nov 7, 2017   
    P=N/A,  N=30, Completed, 
    N=228 --> 68 | Recruiting --> Terminated; Study had a minor contingency that could not be resolved with the IRB. Active, not recruiting --> Completed