Sepsis
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 55 Companies   51 Products   51 Products   62 Mechanisms of Action   0 Trials   1119 News 


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  • ||||||||||  Menveo (meningococcal-groups A, C, W-135 and Y oligosaccharide CRM197 conjugate vaccine) / GSK
    Trial completion, Enrollment change, Trial primary completion date:  Understanding the Immune Response to Two Different Meningitis Vaccines (clinicaltrials.gov) -  Nov 9, 2015   
    P4,  N=20, Completed, 
    Active, not recruiting --> Completed | N=15 --> 20 | Trial primary completion date: Dec 2013 --> Apr 2013
  • ||||||||||  Trial completion:  Early-Onset Sepsis Surveillance Study (clinicaltrials.gov) -  Nov 9, 2015   
    P=N/A,  N=615, Completed, 
    Active, not recruiting --> Completed | N=15 --> 20 | Trial primary completion date: Dec 2013 --> Apr 2013 Active, not recruiting --> Completed
  • ||||||||||  Enrollment change, Trial withdrawal, Trial primary completion date:  DAMSEL2: Dose Assessment of Melatonin in Sepsis Trial (clinicaltrials.gov) -  Nov 6, 2015   
    P1/2,  N=0, Withdrawn, 
    Active, not recruiting --> Completed N=50 --> 0 | Active, not recruiting --> Withdrawn | Trial primary completion date: Nov 2016 --> Dec 2014
  • ||||||||||  Trial primary completion date, Surgery:  Optimizing Prevention of Healthcare-Acquired Infections After Cardiac Surgery (HAI)_2 (clinicaltrials.gov) -  Oct 27, 2015   
    P=N/A,  N=330, Recruiting, 
    N=109 --> 59 | Recruiting --> Terminated | Trial primary completion date: Jan 2016 --> Aug 2015; Due to administrative reasons Trial primary completion date: Sep 2015 --> Sep 2016
  • ||||||||||  tigecycline / Generic mfg., acetylcysteine solution / Generic mfg.
    Trial withdrawal:  Treatment of Hemodialysis Catheter-Related Bacteremia (clinicaltrials.gov) -  Oct 23, 2015   
    P2/3,  N=0, Withdrawn, 
    Trial primary completion date: Oct 2014 --> Oct 2015 Not yet recruiting --> Withdrawn
  • ||||||||||  Prezista (darunavir) / J&J, Isentress (raltegravir) / Merck (MSD)
    Enrollment change, Trial termination, Trial primary completion date:  Management of Participants With Low-level Persistent Viremia (ANRS 161 L-VIR) (clinicaltrials.gov) -  Oct 22, 2015   
    P3,  N=4, Terminated, 
    Recruiting --> Active, not recruiting N=120 --> 4 | Recruiting --> Terminated | Trial primary completion date: Mar 2017 --> Sep 2015; Low recruitment of participants for the study
  • ||||||||||  Enrollment closed, Trial initiation date, Trial primary completion date:  EIDECS: End-of-life Decision-making in Patients With Sepsis-related Organ Failure (clinicaltrials.gov) -  Oct 15, 2015   
    P=N/A,  N=180, Active, not recruiting, 
    N=120 --> 4 | Recruiting --> Terminated | Trial primary completion date: Mar 2017 --> Sep 2015; Low recruitment of participants for the study Recruiting --> Active, not recruiting | Initiation date: Dec 2010 --> Aug 2010 | Trial primary completion date: Jun 2014 --> Oct 2014
  • ||||||||||  Leukine (sargramostim) / Partner Therap
    Trial completion, Trial primary completion date:  Does GM-CSF Restore Neutrophil Phagocytosis in Critical Illness? (clinicaltrials.gov) -  Oct 7, 2015   
    P1/2,  N=70, Completed, 
    Recruiting --> Active, not recruiting | Initiation date: Dec 2010 --> Aug 2010 | Trial primary completion date: Jun 2014 --> Oct 2014 Recruiting --> Completed | Trial primary completion date: Apr 2015 --> Jan 2015
  • ||||||||||  Trial completion, Enrollment change:  SIS Multicenter Study of Duration of Antibiotics for Intraabdominal Infection (clinicaltrials.gov) -  Oct 7, 2015   
    P3,  N=518, Completed, 
    Recruiting --> Completed | Trial primary completion date: Apr 2015 --> Jan 2015 Active, not recruiting --> Completed | N=1120 --> 518
  • ||||||||||  Enrollment change, Trial termination, Trial primary completion date:  Studies of Acute Lung Injury (ALI) and Acute Respiratory Distress Syndrome (clinicaltrials.gov) -  Oct 6, 2015   
    P1,  N=28, Terminated, 
    Active, not recruiting --> Completed | N=1120 --> 518 N=40 --> 28 | Active, not recruiting --> Terminated | Trial primary completion date: Dec 2012 --> Sep 2014; Inability to recruit the patients due to the short supply and changed local hospital protocol
  • ||||||||||  tacrolimus intravenous / Generic mfg., mycophenolate mofetil / Generic mfg., sirolimus / Generic mfg.
    Enrollment closed, Enrollment change:  Using mTOR Inhibitors in the Prevention of BK Nephropathy (clinicaltrials.gov) -  Oct 2, 2015   
    P=N/A,  N=41, Active, not recruiting, 
    N=40 --> 28 | Active, not recruiting --> Terminated | Trial primary completion date: Dec 2012 --> Sep 2014; Inability to recruit the patients due to the short supply and changed local hospital protocol Recruiting --> Active, not recruiting | N=60 --> 41
  • ||||||||||  piperacillin sodium/tazobactam sodium / Generic mfg., amikacin sulfate / Generic mfg.
    Trial completion, Trial primary completion date:  AbProM: Role of Antibiotics in Preventing Infection in Babies Born Through Meconium Stained Liquor (clinicaltrials.gov) -  Sep 29, 2015   
    P=N/A,  N=250, Completed, 
    Recruiting --> Active, not recruiting | N=60 --> 41 Recruiting --> Completed | Trial primary completion date: Dec 2012 --> Jan 2011
  • ||||||||||  Trial completion, Trial primary completion date:  A Trial on Different Dosages of Vitamin D in Preterm Infants With Late-onset Sepsis (clinicaltrials.gov) -  Sep 29, 2015   
    P1,  N=50, Completed, 
    Recruiting --> Completed | Trial primary completion date: Dec 2012 --> Jan 2011 Recruiting --> Completed | Trial primary completion date: Apr 2015 --> Aug 2015
  • ||||||||||  Trial primary completion date:  Serial Therapeutic and Antifungal Monitoring Protocol (clinicaltrials.gov) -  Sep 28, 2015   
    P=N/A,  N=60, Recruiting, 
    Recruiting --> Completed | Trial primary completion date: Apr 2015 --> Aug 2015 Trial primary completion date: Apr 2015 --> Jun 2016
  • ||||||||||  vancomycin / Generic mfg.
    Trial primary completion date:  RCT of Continuous Versus Intermittent Infusion of Vancomycin in Neonates (clinicaltrials.gov) -  Sep 25, 2015   
    P=N/A,  N=200, Recruiting, 
    Not yet recruiting --> Recruiting | Initiation date: Mar 2015 --> Sep 2015 | Trial primary completion date: Apr 2016 --> Sep 2016 Trial primary completion date: Sep 2016 --> Sep 2017
  • ||||||||||  Enrollment change, Trial primary completion date:  Early PREdiction of Severe Sepsis I (ExPRES-Sepsis I) Study (clinicaltrials.gov) -  Sep 25, 2015   
    P=N/A,  N=500, Recruiting, 
    Trial primary completion date: Sep 2016 --> Sep 2017 N=200 --> 500 | Trial primary completion date: Jul 2015 --> Dec 2015
  • ||||||||||  Trial completion, Trial primary completion date:  German Lactat Clearance in Severe Sepsis (clinicaltrials.gov) -  Sep 25, 2015   
    P=N/A,  N=300, Completed, 
    N=200 --> 500 | Trial primary completion date: Jul 2015 --> Dec 2015 Recruiting --> Completed | Trial primary completion date: Jan 2014 --> Apr 2015
  • ||||||||||  Biomarker, Trial completion, Enrollment change:  Hypoxia Inducible Factor 1 Alpha as a Novel Biomarker in Septic Shock (clinicaltrials.gov) -  Sep 18, 2015   
    P=N/A,  N=63, Completed, 
    Recruiting --> Completed | Trial primary completion date: Jan 2014 --> Apr 2015 Recruiting --> Completed | N=130 --> 63
  • ||||||||||  Enrollment closed, Trial primary completion date:  Near Infrared Spectroscopy (St02) (clinicaltrials.gov) -  Sep 10, 2015   
    P=N/A,  N=300, Active, not recruiting, 
    Not yet recruiting --> Recruiting | Trial primary completion date: Jun 2015 --> Mar 2016 Recruiting --> Active, not recruiting | Trial primary completion date: Sep 2010 --> Sep 2016
  • ||||||||||  simvastatin / Generic mfg.
    Trial completion, Enrollment change, Trial primary completion date:  Statin Therapy in the Treatment of Sepsis (clinicaltrials.gov) -  Sep 9, 2015   
    P2/3,  N=13, Completed, 
    Recruiting --> Completed Recruiting --> Completed | N=60 --> 13 | Trial primary completion date: Dec 2013 --> Dec 2010
  • ||||||||||  Trial completion:  Thiamine as a Metabolic Resuscitator in Septic Shock (clinicaltrials.gov) -  Sep 8, 2015   
    P1/2,  N=80, Completed, 
    Recruiting --> Completed | N=60 --> 13 | Trial primary completion date: Dec 2013 --> Dec 2010 Recruiting --> Completed
  • ||||||||||  Trial completion, Trial primary completion date:  Ubiquinol (Reduced COQ10) for Patients With Sepsis (clinicaltrials.gov) -  Sep 8, 2015   
    P2,  N=38, Completed, 
    Recruiting --> Completed Recruiting --> Completed | Trial primary completion date: Dec 2013 --> Apr 2014
  • ||||||||||  Trial completion, Enrollment change:  IMproved PREdiction of Severe Sepsis in the Emergency Department (clinicaltrials.gov) -  Sep 3, 2015   
    P=N/A,  N=759, Completed, 
    N=50 --> 0 | Not yet recruiting --> Withdrawn Active, not recruiting --> Completed | N=1000 --> 759
  • ||||||||||  Trial primary completion date:  The Paediatric Refill Study (PRefill) (clinicaltrials.gov) -  Aug 22, 2015   
    P=N/A,  N=135, Recruiting, 
    N=120 --> 80 Trial primary completion date: May 2015 --> Dec 2015
  • ||||||||||  Trial initiation date, Trial primary completion date:  Actigraphy to MEasuRe Intensive Care Unit Activity (clinicaltrials.gov) -  Aug 13, 2015   
    P=N/A,  N=75, Recruiting, 
    Completed --> Terminated; Not participants inclusion Initiation date: Oct 2014 --> Jul 2015 | Trial primary completion date: Sep 2015 --> Dec 2015
  • ||||||||||  Phase classification, Trial initiation date, Trial primary completion date:  Post Marketing Surveillance Study To Observe Safety And Efficacy Of Eraxis® IV (clinicaltrials.gov) -  Aug 13, 2015   
    P=N/A,  N=200, Active, not recruiting, 
    Initiation date: Oct 2014 --> Jul 2015 | Trial primary completion date: Sep 2015 --> Dec 2015 Phase classification: P4 --> P=N/A | Initiation date: Mar 2012 --> Aug 2012 | Trial primary completion date: Jul 2015 --> Feb 2016
  • ||||||||||  fludrocortisone / Generic mfg., hydrocortisone / Generic mfg.
    Trial completion, Trial primary completion date:  APROCCHS: Activated Protein C and Corticosteroids for Human Septic Shock (clinicaltrials.gov) -  Aug 12, 2015   
    P3,  N=1241, Completed, 
    Phase classification: P4 --> P=N/A | Initiation date: Mar 2012 --> Aug 2012 | Trial primary completion date: Jul 2015 --> Feb 2016 Recruiting --> Completed | Trial primary completion date: Dec 2014 --> Jun 2015
  • ||||||||||  Enrollment closed:  SIFT: Speed of Increasing Milk Feeds Trial (clinicaltrials.gov) -  Aug 12, 2015   
    P=N/A,  N=2806, Active, not recruiting, 
    N=128 --> 40 | Active, not recruiting --> Terminated | Trial primary completion date: Aug 2013 --> Apr 2013; Problems implementing the trial Recruiting --> Active, not recruiting