Sepsis MOAs - LARVOL Sigma

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Sepsis

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Phase N/A 1 2 3 4 Products	0	2	4	6	8	10	12	14	16	18	20



Immunostimulant




IFNα stim




CD28 inhib




DNA synthesis inhib




Factor IX inhib




Factor X inhib




GCR agon




HMG-CoA reductase inhib




NMDAR antag




Nicotinic receptor agon




PPAR γ agon




Protease inhib




VEGF inhib




VEGF-A inhib




mTOR inhib




5-lipoxygenase activating protein inhib




AKT inhib




Angiogenesis inhib




Bone morphogenetic protein receptor type II mod




CD20-targeted radiotherapeutic antibody




CD28 inhib




CD28 inhib




Calcineurin inhib




Calcium sensitizer




Calcium-binding protein mod




Cardiac specific myosin activator




DGAT inhib




DHODH inhib




DNA polymerase inhib




DNA synthesis inhib




Endotoxin inhib




Enzyme replacement therapy




Fatty acid inhib




GLP-1 receptor agon




GM-CSF agon




GM-CSF agon




HCN channel inhib




HIF-1 inhib




HIF-1 inhib




Hepcidin mod




IL-6 inhib




IL-6 inhib




Immunosuppressant




Ionizing radiation emitter




K+ channel agon




LMWH inhib




LPS inhib




MMP inhib




Na+ channel Nav 1.7 inhib




Natriuretic peptide receptor B agon



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