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21 Companies |
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19 Products |
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24 Mechanisms of Action |
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0 Trials |
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452 News |
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- Trial completion date: Intensive Nutrition in Acute Respiratory Distress Syndrome (ARDS): A Clinical Trial (INTACT) (clinicaltrials.gov) - Apr 14, 2014
P=N/A, N=78, Completed, Sponsor: University of Illinois at Chicago
Trial completion date: Jun 2014 --> Jun 2013
- Enrollment change: Intensive Nutrition in Acute Respiratory Distress Syndrome (ARDS): A Clinical Trial (INTACT) (clinicaltrials.gov) - Apr 14, 2014
P=N/A, N=78, Completed, Sponsor: University of Illinois at Chicago
Trial completion date: Jun 2014 --> Jun 2013 N=200 --> 78
- Trial completion: Intensive Nutrition in Acute Respiratory Distress Syndrome (ARDS): A Clinical Trial (INTACT) (clinicaltrials.gov) - Apr 14, 2014
P=N/A, N=78, Completed, Sponsor: University of Illinois at Chicago
N=200 --> 78 Recruiting --> Completed
- ||||| H.P. Acthar Gel (repository corticotropin injection) / Mallinckrodt
New P2 trial: Safety and Efficacy Study of Acthar in Subjects With ARDS (clinicaltrials.gov) - Apr 13, 2014
P2, N=210, Not yet recruiting, Sponsor: Questcor Pharmaceuticals, Inc.
- ||| Clinical: RINO: Impact of Nasal High-flow vs Venturi Mask Oxygen Therapy on Weaning Outcome: a Multicenter, Randomized, Controlled Trial (clinicaltrials.gov) - Apr 6, 2014
P=N/A, N=500, Not yet recruiting, Sponsor: Catholic University of the Sacred Heart
- Trial completion: Effect of Volume and Type of Fluid on Postoperative Incidence of Respiratory Complications and Outcome (CRC-Study) (clinicaltrials.gov) - Apr 1, 2014
P=N/A, N=104000, Completed, Sponsor: Massachusetts General Hospital
Recruiting --> Completed Not yet recruiting --> Completed
- | New P2 trial, Stroma: Human Mesenchymal Stromal Cells For Acute Respiratory Distress Syndrome (START) (clinicaltrials.gov) - Mar 25, 2014
P2, N=60, Not yet recruiting, Sponsor: Michael A. Matthay
- Trial completion: TPG in HFO: Transpulmonary Pressure Gradients in High Frequency Oscillation (clinicaltrials.gov) - Mar 13, 2014
P=N/A, N=7, Completed, Sponsor: University of British Columbia
Not yet recruiting --> Completed Recruiting --> Completed
- Trial completion: Australia and New Zealand Adult Extracorporeal Membrane Oxygenation (ECMO) Audit 2005 (clinicaltrials.gov) - Mar 5, 2014
P=N/A, N=0, Completed, Sponsor: Bayside Health
Recruiting --> Completed Recruiting --> Completed
- Biomarker, Enrollment closed: Acute Lung Injury Ventilator Evaluation (ALIVE) (clinicaltrials.gov) - Mar 4, 2014
P=N/A, N=100, Active, not recruiting, Sponsor: University of Wisconsin, Madison
Recruiting --> Completed Recruiting --> Active, not recruiting
- ||| Enrollment open: OPTINIV: Pilot Study of High-flow Humidified Nasal Oxygen During Breaks From Noninvasive Ventilation (clinicaltrials.gov) - Feb 17, 2014
P=N/A, N=70, Recruiting, Sponsor: Tufts Medical Center
Recruiting --> Active, not recruiting Not yet recruiting --> Recruiting
- Enrollment open: Large Observational Study to UNderstand the Global Impact of Severe Acute Respiratory FailurE (clinicaltrials.gov) - Feb 17, 2014
P=N/A, N=1000, Recruiting, Sponsor: European Society of Intensive Care Medicine
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- rocuronium / Generic mfg.
Clinical: Supported Ventilation in ARDS Patients (clinicaltrials.gov) - Feb 13, 2014
P=N/A, N=12, Recruiting, Sponsor: University Medical Center Nijmegen
- Trial completion: EDDRA-Repro: Reproductibility of TM-mode Ultrasound Diaphragm Measures in Patients With Acute Respiratory Distress in the ER (clinicaltrials.gov) - Jan 29, 2014
P=N/A, N=26, Completed, Sponsor: Centre Hospitalier Universitaire de Nīmes
Not yet recruiting --> Recruiting Recruiting --> Completed
- Trial initiation date: Cross-section Survey of Mechanical Ventilation and Acute Respiratory Distress Syndrome in China (clinicaltrials.gov) - Jan 23, 2014
P=N/A, N=1000, Recruiting, Sponsor: Southeast University, China
Recruiting --> Completed Initiation date: Sep 2012 --> Jan 2014
- Enrollment open: Cross-section Survey of Mechanical Ventilation and Acute Respiratory Distress Syndrome in China (clinicaltrials.gov) - Jan 23, 2014
P=N/A, N=1000, Recruiting, Sponsor: Southeast University, China
Initiation date: Sep 2012 --> Jan 2014 Not yet recruiting --> Recruiting
- Trial completion, Surgery: BIPAP Vision Versus OPTIFLOW System Comparison in Acute Respiratory Failure After Cardio Thoracic Surgery (clinicaltrials.gov) - Jan 22, 2014
P=N/A, N=830, Completed, Sponsor: Centre Chirurgical Marie Lannelongue
Not yet recruiting --> Recruiting Recruiting --> Completed
- | Trial completion: Noninvasive Continuous Positive Airway Pressure (NCPAP) in Children (clinicaltrials.gov) - Jan 20, 2014
P3, N=60, Completed, Sponsor: Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
Recruiting --> Completed Recruiting --> Completed
- midazolam hydrochloride / Generic mfg.
Enrollment change: PISA: Pharmacologic Impact on Sedation Assessments (clinicaltrials.gov) - Jan 16, 2014
P=N/A, N=175, Completed, Sponsor: Children's Hospital of Philadelphia
Recruiting --> Completed N=500 --> 175
- midazolam hydrochloride / Generic mfg.
Trial completion: PISA: Pharmacologic Impact on Sedation Assessments (clinicaltrials.gov) - Jan 16, 2014
P=N/A, N=175, Completed, Sponsor: Children's Hospital of Philadelphia
N=500 --> 175 Recruiting --> Completed
- simvastatin / Generic mfg.
Trial withdrawal: Simvastatin Effect on the Incidence of Acute Lung Injury/Adult Respiratory Distress Syndrome (ALI/ARDS) (clinicaltrials.gov) - Jan 5, 2014
P=N/A, N=0, Withdrawn, Sponsor: University of Oklahoma
Recruiting --> Completed Terminated --> Withdrawn
- New P1 trial: Automatic Administration of Oxygen During Respiratory Distress (clinicaltrials.gov) - Jan 2, 2014
P1, N=140, Recruiting, Sponsor: University Hospital, Brest
- New P1 trial: Physiological Study of Low-frequency HFO/HFO-TGI and High-frequency HFO (clinicaltrials.gov) - Jan 1, 2014
P1, N=16, Recruiting, Sponsor: University of Athens
- Trial completion: Helmet Continuous Positive Airway Pressure (CPAP) Versus Oxygen Venturi in Severe Acute Respiratory Failure in Pneumonia (clinicaltrials.gov) - Dec 30, 2013
P=N/A, N=81, Completed, Sponsor: University of Milan
Terminated --> Withdrawn Recruiting --> Completed
- Enbrel (etanercept) / Pfizer, Amgen
Enrollment change: Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant (clinicaltrials.gov) - Dec 26, 2013
P2, N=34, Completed, Sponsor: University of Michigan Cancer Center
Recruiting --> Completed N=25 --> 34
- Enbrel (etanercept) / Pfizer, Amgen
Trial completion: Study of Enbrel (Etanercept) for the Treatment Sub-Acute Pulmonary Dysfunction After Allogeneic Stem Cell Transplant (clinicaltrials.gov) - Dec 26, 2013
P2, N=34, Completed, Sponsor: University of Michigan Cancer Center
N=25 --> 34 Active, not recruiting --> Completed
- | Trial completion: PROPPR: Pragmatic, Randomized Optimal Platelet and Plasma Ratios (clinicaltrials.gov) - Dec 18, 2013
P3, N=680, Completed, Sponsor: The University of Texas Health Science Center, Houston
Active, not recruiting --> Completed Recruiting --> Completed
- Turnobi (L-citrulline intravenous) / Asklepion Pharma
Enrollment open: Citrulline in Severe Sepsis (clinicaltrials.gov) - Dec 15, 2013
P2, N=75, Recruiting, Sponsor: Vanderbilt University
Recruiting --> Completed Not yet recruiting --> Recruiting
- Trial termination: High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Dec 11, 2013
P2/3, N=42, Terminated, Sponsor: University of Athens
Not yet recruiting --> Recruiting Active, not recruiting --> Terminated; Low rate of enrollment, in conjunction with inability of continuation of funding
- Enrollment change: High Frequency Oscillatory Ventilation for Acute Respiratory Distress Syndrome (ARDS) (clinicaltrials.gov) - Dec 11, 2013
P2/3, N=42, Terminated, Sponsor: University of Athens
Active, not recruiting --> Terminated; Low rate of enrollment, in conjunction with inability of continuation of funding N=204 --> 42
- | Enrollment change: Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury (clinicaltrials.gov) - Dec 8, 2013
P2/3, N=63, Completed, Sponsor: Beth Israel Deaconess Medical Center
N=204 --> 42 N=200 --> 63
- | Trial completion: Mechanical Ventilation, Directed by Esophageal Pressure Measurements, in Patients With Acute Lung Injury (clinicaltrials.gov) - Dec 8, 2013
P2/3, N=63, Completed, Sponsor: Beth Israel Deaconess Medical Center
N=200 --> 63 Active, not recruiting --> Completed
- Trial initiation date: PRoVENT: Practice of Ventilation in Critically Ill Patients Without ARDS (clinicaltrials.gov) - Nov 26, 2013
P=N/A, N=1000, Not yet recruiting, Sponsor: Marcus J Schultz
Active, not recruiting --> Completed Initiation date: Jan 2014 --> Apr 2014
- Enrollment change: PRoVENT: Practice of Ventilation in Critically Ill Patients Without ARDS (clinicaltrials.gov) - Nov 26, 2013
P=N/A, N=1000, Not yet recruiting, Sponsor: Marcus J Schultz
Initiation date: Jan 2014 --> Apr 2014 N=800 --> 1000
- Trial suspension: CEASE: Comparative Evaluation of Albumin and Starch Effects in Acute Lung Injury (ALI) (clinicaltrials.gov) - Nov 20, 2013
P3, N=60, Suspended, Sponsor: Emory University
N=800 --> 1000 Recruiting --> Suspended
- Enrollment change: AMFAS: Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis (clinicaltrials.gov) - Nov 20, 2013
P=N/A, N=80, Active, not recruiting, Sponsor: Emory University
Recruiting --> Suspended N=100 --> 80
- Enrollment closed: AMFAS: Study of the Function of Cells Involved in Inflammation in the Lungs of Those With Acute Lung Injury and Sepsis (clinicaltrials.gov) - Nov 20, 2013
P=N/A, N=80, Active, not recruiting, Sponsor: Emory University
N=100 --> 80 Recruiting --> Active, not recruiting
- Enrollment change, Surgery: LAS VEGAS: Local Assessment of Ventilatory Management During General Anesthesia for Surgery (clinicaltrials.gov) - Nov 19, 2013
P=N/A, N=10690, Completed, Sponsor: European Society of Anaesthesiology
Recruiting --> Active, not recruiting N=4800 --> 10690
- Trial completion, Surgery: LAS VEGAS: Local Assessment of Ventilatory Management During General Anesthesia for Surgery (clinicaltrials.gov) - Nov 19, 2013
P=N/A, N=10690, Completed, Sponsor: European Society of Anaesthesiology
N=4800 --> 10690 Recruiting --> Completed
- Enrollment open: Intensive Care - GLObal Study on Severe Acute Respiratory Infection (clinicaltrials.gov) - Nov 13, 2013
P=N/A, N=4000, Recruiting, Sponsor: European Society of Intensive Care Medicine
Recruiting --> Completed Not yet recruiting --> Recruiting
- Biomarker, Enrollment open: IFRA2: Validation of the Percentage of Alveolar Fibrocyte as Biomarker During ARDS (clinicaltrials.gov) - Nov 11, 2013
P=N/A, N=84, Recruiting, Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting --> Recruiting Not yet recruiting --> Recruiting
- Trial termination: Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet (clinicaltrials.gov) - Nov 3, 2013
P=N/A, N=23, Terminated, Sponsor: University of Parma
Not yet recruiting --> Recruiting Recruiting --> Terminated; Failed to reach expected enrollment by anticipated dates.
- Enrollment change: Continuous Positive Airway Pressure (CPAP) Ventilation Using a Novel Full-Face Mask Versus Conventional Helmet (clinicaltrials.gov) - Nov 3, 2013
P=N/A, N=23, Terminated, Sponsor: University of Parma
Recruiting --> Terminated; Failed to reach expected enrollment by anticipated dates. N=50 --> 23
- TNKASE (tenecteplase) / Roche, Boehringer Ingelheim
Trial withdrawal: Treatment of Acute Respiratory Distress Syndrome With Tenecteplase: A Dose Escalation Pilot Study (clinicaltrials.gov) - Nov 3, 2013
P1, N=0, Withdrawn, Sponsor: Medical Center of Central Georgia
N=50 --> 23 Recruiting --> Withdrawn
- TNKASE (tenecteplase) / Roche, Boehringer Ingelheim
Enrollment change: Treatment of Acute Respiratory Distress Syndrome With Tenecteplase: A Dose Escalation Pilot Study (clinicaltrials.gov) - Nov 3, 2013
P1, N=0, Withdrawn, Sponsor: Medical Center of Central Georgia
Recruiting --> Withdrawn N=20 --> 0
- rosuvastatin / Generic mfg.
Trial termination: SAILS: Statins for Acutely Injured Lungs From Sepsis (clinicaltrials.gov) - Oct 17, 2013
P3, N=745, Terminated, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
N=20 --> 0 Recruiting --> Terminated; stopped for futility
- rosuvastatin / Generic mfg.
Enrollment change: SAILS: Statins for Acutely Injured Lungs From Sepsis (clinicaltrials.gov) - Oct 17, 2013
P3, N=745, Terminated, Sponsor: National Heart, Lung, and Blood Institute (NHLBI)
Recruiting --> Terminated; stopped for futility N=1000 --> 745
- Trial termination: OPTI O2: Evaluation of Oxygen Therapy Delivery Systems in Hypoxemic Acute Respiratory Failure (clinicaltrials.gov) - Oct 3, 2013
P=N/A, N=16, Terminated, Sponsor: Nantes University Hospital
N=1000 --> 745 Recruiting --> Terminated; Difficulty of recruitment
- Enrollment change: OPTI O2: Evaluation of Oxygen Therapy Delivery Systems in Hypoxemic Acute Respiratory Failure (clinicaltrials.gov) - Oct 3, 2013
P=N/A, N=16, Terminated, Sponsor: Nantes University Hospital
Recruiting --> Terminated; Difficulty of recruitment N=24 --> 16
- Trial completion, Metastases: Diffuse Acute Respiratory Distress Syndrome (ARDS), Recruitment Maneuver, and sRAGE (DAMAGE Study) (clinicaltrials.gov) - Sep 30, 2013
P4, N=24, Completed, Sponsor: University Hospital, Clermont-Ferrand
N=24 --> 16 Recruiting --> Completed