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84 Companies |
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113 Products |
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113 Products |
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110 Mechanisms of Action |
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3 Trials |
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2476 News |
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- dexmedetomidine / Generic mfg.
Clinical: Dexmedetomidine Pharmacokinetics-pharmacodynamics in Mechanically Ventilated Children With Single-organ Respiratory Failure (clinicaltrials.gov) - Oct 2, 2011
P3, N=1, Terminated, Sponsor: University Hospital, Ghent
N=48 --> 1
- ||| Trial completion: Postoperative Residual Curarisation at Arrival in the Post-anesthesia Care Unit (clinicaltrials.gov) - Oct 2, 2011
P=N/A, N=625, Completed, Sponsor: Onze Lieve Vrouw Hospital
N=48 --> 1 Recruiting --> Completed
- Trial completion: Identification of Sleep-Disordered Breathing in Children (clinicaltrials.gov) - Oct 2, 2011
P=N/A, N=160, Completed, Sponsor: University of Michigan
Recruiting --> Completed Active, not recruiting --> Completed
- Clinical: The Effect of Reflective Breathing Therapy Compared With Conventional Breathing Therapy in Patients With Chronic Obstructive Pulmonary Disease (COPD) III-IV (clinicaltrials.gov) - Sep 29, 2011
P=N/A, N=24, Completed, Sponsor: Klinikum Berchtesgadener Land der Schön-Kliniken
- | Traumakine (IFN beta-1a) / Faron Pharma, Maruishi Pharma
Trial completion: Safety, Tolerability and Preliminary Efficacy of FP-1201 in ALI and ARDS. Phase I/II (clinicaltrials.gov) - Sep 29, 2011
P1/2, N=37, Completed, Sponsor: Faron Pharmaceuticals Ltd
Active, not recruiting --> Completed Active, not recruiting --> Completed
- |||| Daliresp (roflumilast) / AstraZeneca, Takeda, AbbVie
Enrollment open: Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting ?2-agonist (LABA) and Inhaled Corticosteroid (ICS) (clinicaltrials.gov) - Sep 29, 2011
P4, N=2300, Recruiting, Sponsor: Forest Laboratories
Active, not recruiting --> Completed Not yet recruiting --> Recruiting
- | Belsomra (suvorexant) / Merck (MSD)
Trial completion: Effects of Suvorexant in Participants With Obstructive Sleep Apnea (MK-4305-036) (clinicaltrials.gov) - Sep 29, 2011
P1, N=26, Completed, Sponsor: Merck Sharp & Dohme Corp.
Not yet recruiting --> Recruiting Recruiting --> Completed
- Trial completion: A Phase II Randomized Trial of Fish Oil in Patients With Acute Lung Injury (ALI) (clinicaltrials.gov) - Sep 29, 2011
P2, N=90, Completed, Sponsor: University of Washington
Recruiting --> Completed Active, not recruiting --> Completed
- | azithromycin / Generic mfg.
New P4 trial: AZALEA: AZithromycin Against pLacebo in Exacerbations of Asthma (clinicaltrials.gov) - Sep 28, 2011
P4, N=350, Recruiting, Sponsor: Imperial College London
- ||||| Daliresp (roflumilast) / AstraZeneca, Takeda, AbbVie
New P4 trial: Roflumilast in Chronic Obstructive Pulmonary Disease (COPD) Patients Treated With Fixed Dose Combinations of Long-acting ?2-agonist (LABA) and Inhaled Corticosteroid (ICS) (clinicaltrials.gov) - Sep 28, 2011
P4, N=2300, Recruiting, Sponsor: Forest Laboratories
- acetazolamide / Generic mfg.
Trial termination: Buspirone as a Potential Treatment for Recurrent Central Apnea (clinicaltrials.gov) - Sep 25, 2011
P3, N=28, Terminated, Sponsor: Department of Veterans Affairs
Active, not recruiting --> Completed Recruiting --> Terminated; Patient recruitment and Funding inadequate to finish trial
- | Enrollment open: ASPEN: Surfactant Versus Nasal Continuous Positive Airway Pressure (nCPAP) for Respiratory Distress Syndrome in the Newborn ≥ 35 Weeks of Gestation (clinicaltrials.gov) - Sep 25, 2011
P3, N=152, Recruiting, Sponsor: Centre Hospitalier Universitaire, Amiens
Recruiting --> Terminated; Patient recruitment and Funding inadequate to finish trial Not yet recruiting --> Recruiting
- Trial completion: Activity of Inspiratory Muscles With the Use of Positive Pressure in Patients With Chronic Obstructive Pulmonary Disease (clinicaltrials.gov) - Sep 25, 2011
P=N/A, N=40, Completed, Sponsor: Hospital de Clinicas de Porto Alegre
Not yet recruiting --> Recruiting Recruiting --> Completed
- furosemide / Generic mfg.
New P1/2 trial: Aerosol Inhalation Treatment for Dyspnea (clinicaltrials.gov) - Sep 25, 2011
P1/2, N=24, Recruiting, Sponsor: Beth Israel Deaconess Medical Center
- |||| Valcyte (valganciclovir) / Roche, Mitsubishi Tanabe, Cytovene (ganciclovir) / Roche
Enrollment open: GRAIL: Ganciclovir/Valganciclovir for Prevention of CMV Reactivation in Acute Injury of the Lung and Respiratory Failure (clinicaltrials.gov) - Sep 22, 2011
P2, N=160, Recruiting, Sponsor: Fred Hutchinson Cancer Research Center
Recruiting --> Completed Not yet recruiting --> Recruiting
- | ALT 836 / ImmunityBio
New P1 trial: Effects of TNX-832 (Sunol cH36) in Subjects With Acute Lung Injury/Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Sep 19, 2011
P1, N=18, Completed, Sponsor: Altor Bioscience Corporation
- Trial completion: Neural Control of Non-invasive Ventilation in the Preterm (clinicaltrials.gov) - Sep 19, 2011
P1, N=24, Completed, Sponsor: Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
Not yet recruiting --> Recruiting Recruiting --> Completed
- Curosurf (poractant alfa) / Chiesi
Trial termination: Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants (clinicaltrials.gov) - Sep 18, 2011
P4, N=52, Terminated, Sponsor: Alan Fujii
Recruiting --> Completed Recruiting --> Terminated; Slow recruitment,changes in protocols, larger than anticipated differences
- Curosurf (poractant alfa) / Chiesi
Enrollment change: Curosurf and Survanta Treatment(CAST)of RDS in Very Premature Infants (clinicaltrials.gov) - Sep 18, 2011
P4, N=52, Terminated, Sponsor: Alan Fujii
Recruiting --> Terminated; Slow recruitment,changes in protocols, larger than anticipated differences N=70 --> 52
- Clinical: Long Term (1 Year) Respiratory Sequelae in Children Surviving an Acute Respiratory Distress Syndrome (clinicaltrials.gov) - Sep 15, 2011
P=N/A, N=45, Recruiting, Sponsor: University Hospital, Lille
- Trial termination: Early Rehabilitation of COPD Patients in ICU (clinicaltrials.gov) - Sep 14, 2011
P=N/A, N=240, Terminated, Sponsor: University Hospital, Strasbourg, France
N=70 --> 52 Recruiting --> Terminated
- Enrollment change: Cough Responses to Tussive Agents in Health and Disease (clinicaltrials.gov) - Sep 14, 2011
P=N/A, N=102, Completed, Sponsor: University Hospital of South Manchester NHS Foundation Trust
Recruiting --> Terminated N=150 --> 102
- Trial completion: Cough Responses to Tussive Agents in Health and Disease (clinicaltrials.gov) - Sep 14, 2011
P=N/A, N=102, Completed, Sponsor: University Hospital of South Manchester NHS Foundation Trust
N=150 --> 102 Recruiting --> Completed
- lignocaine / Generic mfg.
Trial completion: Lidocaine: Effect of Lidocaine in Chronic Cough (clinicaltrials.gov) - Sep 14, 2011
P4, N=30, Completed, Sponsor: University Hospital of South Manchester NHS Foundation Trust
Recruiting --> Completed Not yet recruiting --> Completed
- New P1/2 trial: Ascorbic Acid (Vitamin C) Infusion in Human Sepsis (clinicaltrials.gov) - Sep 12, 2011
P1/2, N=24, Completed, Sponsor: Virginia Commonwealth University
- Onbrez (indacaterol) / Novartis
Trial completion: Effect of Indacaterol Maleate in Chronic Obstructive Pulmonary Disease (COPD) on Lung Volume and Related Dyspnea (clinicaltrials.gov) - Sep 7, 2011
P4, N=30, Completed, Sponsor: University of Milan
Not yet recruiting --> Completed Active, not recruiting --> Completed
- Trial completion: SASS: Efficacy of Continuous Positive Airway Pressure in Reducing Oxidative Stress in Individuals With Sleep Apnea (clinicaltrials.gov) - Sep 5, 2011
P=N/A, N=149, Completed, Sponsor: Case Western Reserve University
Active, not recruiting --> Completed Recruiting --> Completed
- |||||||||| New P3 trial: Apnex Clinical Study of the Hypoglossal Nerve Stimulation (HGNS®) System to Treat Obstructive Sleep Apnea (clinicaltrials.gov) - Sep 1, 2011
P3, N=132, Recruiting, Sponsor: Apnex Medical, Inc.
- Trial completion: Three Dimensional Morphology of Upper Respiratory Tract and Mandibular Position on Obstructive Sleep Apnea (clinicaltrials.gov) - Sep 1, 2011
P=N/A, N=20, Completed, Sponsor: National Taiwan University Hospital
Recruiting --> Completed Recruiting --> Completed
- | Humira (adalimumab) / AbbVie
Trial completion: Efficacy and Safety of Adalimumab in Patients With Psoriasis and Obstructive Sleep Apnea (clinicaltrials.gov) - Aug 31, 2011
P4, N=20, Completed, Sponsor: Innovaderm Research Inc.
Recruiting --> Completed Active, not recruiting --> Completed
- acetazolamide / Generic mfg.
New P2 trial: CSRPH: Treatment of Sleep Related Breathing Disorders in Patients With Pulmonary Hypertension (clinicaltrials.gov) - Aug 30, 2011
P2, N=23, Completed, Sponsor: University of Zurich
- Enrollment change: Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology (clinicaltrials.gov) - Aug 24, 2011
P=N/A, N=63, Completed, Sponsor: Children's Mercy Hospital Kansas City
Active, not recruiting --> Completed N=450 --> 63
- Trial completion: SEDA-FIBRO: Broncho-alveolar Lavage Under Noninvasive Ventilation With Propofol TCI in Patient With AHRF (clinicaltrials.gov) - Aug 24, 2011
P3, N=46, Completed, Sponsor: University Hospital, Bordeaux
N=450 --> 63 Recruiting --> Completed
- Trial completion: Genomics, Single Nucleotide Polymorphisms (SNPs), and Clinical Neonatology (clinicaltrials.gov) - Aug 24, 2011
P=N/A, N=63, Completed, Sponsor: Children's Mercy Hospital Kansas City
Recruiting --> Completed Active, not recruiting --> Completed
- Enrollment change: Study of the Usability and Efficacy of a New Pediatric CPAP Mask (clinicaltrials.gov) - Aug 23, 2011
P=N/A, N=6, Completed, Sponsor: ResMed
Active, not recruiting --> Completed N=10 --> 6
- ||| AZD 2423 / AstraZeneca
Enrollment change: Investigation of the Effect of Oral Treatment With 100 mg AZD2423 in Subjects With Mild Chronic Obstructive Pulmonary Disease (COPD) (clinicaltrials.gov) - Aug 23, 2011
P2a, N=71, Completed, Sponsor: AstraZeneca
N=10 --> 6 N=44 --> 71
- Trial completion: Study of the Usability and Efficacy of a New Pediatric CPAP Mask (clinicaltrials.gov) - Aug 23, 2011
P=N/A, N=6, Completed, Sponsor: ResMed
N=44 --> 71 Recruiting --> Completed
- |||| AZD 2423 / AstraZeneca
Trial completion: Investigation of the Effect of Oral Treatment With 100 mg AZD2423 in Subjects With Mild Chronic Obstructive Pulmonary Disease (COPD) (clinicaltrials.gov) - Aug 23, 2011
P2a, N=71, Completed, Sponsor: AstraZeneca
Recruiting --> Completed Active, not recruiting --> Completed
- New P2 trial: Lifestyle Interventions for Seniors With Apnea (clinicaltrials.gov) - Aug 22, 2011
P2, N=20, Recruiting, Sponsor: Johns Hopkins University
- Enrollment closed: Buspirone in Reducing Shortness of Breath in Patients With Cancer (clinicaltrials.gov) - Aug 21, 2011
P=N/A, N=376, Active, not recruiting, Sponsor: University of Rochester
Active, not recruiting --> Completed Completed --> Active, not recruiting
- ||| AZD2115 / Pulmagen Therap, AstraZeneca
Trial completion: AZD2115 Single Ascending Dose Study (clinicaltrials.gov) - Aug 16, 2011
P1, N=96, Completed, Sponsor: AstraZeneca
Completed --> Active, not recruiting Recruiting --> Completed
- Trial completion: Non-invasive Ventilation in Terminally Ill Cancer Patients (clinicaltrials.gov) - Aug 16, 2011
P4, N=200, Completed, Sponsor: Azienda Ospedaliera Universitaria di Bologna Policlinico S. Orsola Malpighi
Recruiting --> Completed Recruiting --> Completed
- Trial termination: Clinical Trial of a Computer-driven Weaning System for Patients Requiring Mechanical Ventilation (clinicaltrials.gov) - Aug 15, 2011
P=N/A, N=33, Terminated, Sponsor: Boston Medical Center
Recruiting --> Completed Enrolling by invitation --> Terminated; Slow recruitment of subjects
- Enrollment change: Clinical Trial of a Computer-driven Weaning System for Patients Requiring Mechanical Ventilation (clinicaltrials.gov) - Aug 15, 2011
P=N/A, N=33, Terminated, Sponsor: Boston Medical Center
Enrolling by invitation --> Terminated; Slow recruitment of subjects N=220 --> 33
- Enrollment open: ST Elevation in Acute Chest Pain; Could Measurement of Lipoprotein-associated Phospholipase A2 (Lp-PLA2) be Helpful to the Clinician? (clinicaltrials.gov) - Aug 15, 2011
P=N/A, N=100, Recruiting, Sponsor: Wolfson Medical Center
N=220 --> 33 Not yet recruiting --> Recruiting
- | acetazolamide / Generic mfg.
New P4 trial: A Trial of Acetazolamide Versus Placebo in Preventing Mountain Sickness During Rapid Ascent (clinicaltrials.gov) - Aug 14, 2011
P4, N=380, Completed, Sponsor: Oxford University Clinical Research Unit, Vietnam
- Trial termination: MAVAS: Acoustic Reflection Method and Work of Breathing (clinicaltrials.gov) - Aug 7, 2011
P=N/A, N=38, Terminated, Sponsor: Assistance Publique - Hôpitaux de Paris
Not yet recruiting --> Recruiting Recruiting --> Terminated; No inclusion
- Trial termination: Nemucough: Evaluation of a Mechanical Device During Acute Respiratory Failure in Patients With Neuromuscular Disorders (clinicaltrials.gov) - Aug 7, 2011
P3, N=14, Terminated, Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting --> Terminated; No inclusion Recruiting --> Terminated; No inclusion
- Enrollment change: MAVAS: Acoustic Reflection Method and Work of Breathing (clinicaltrials.gov) - Aug 7, 2011
P=N/A, N=38, Terminated, Sponsor: Assistance Publique - Hôpitaux de Paris
Recruiting --> Terminated; No inclusion N=120 --> 38
- Enrollment change: Nemucough: Evaluation of a Mechanical Device During Acute Respiratory Failure in Patients With Neuromuscular Disorders (clinicaltrials.gov) - Aug 7, 2011
P3, N=14, Terminated, Sponsor: Assistance Publique - Hôpitaux de Paris
N=120 --> 38 N=110 --> 14