Respiration Disorders
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  • ||||||||||  Trial termination:  Hantavirus Transmission in Households in Chile (clinicaltrials.gov) -  Jan 11, 2024   
    P=N/A,  N=197, Terminated, 
    N=30 --> 50 Completed --> Terminated; This is not a clinical trial and was inadvertently added to the system.
  • ||||||||||  Enrollment change, Trial withdrawal:  Non-Inferiority Trial of Acute HFT Versus nCPAP (clinicaltrials.gov) -  May 3, 2023   
    P=N/A,  N=0, Withdrawn, 
    Completed --> Terminated; This is not a clinical trial and was inadvertently added to the system. N=56 --> 0 | Completed --> Withdrawn
  • ||||||||||  Trial completion:  RCT ATE/ATT: ATT Compared With ATE in OSAS Children (clinicaltrials.gov) -  Mar 10, 2023   
    P=N/A,  N=79, Completed, 
    N=56 --> 0 | Completed --> Withdrawn Unknown status --> Completed
  • ||||||||||  betamethasone / Generic mfg.
    Trial completion, Trial completion date:  Betamethasone and Severity of Hyaline Membrane Disease (clinicaltrials.gov) -  Apr 20, 2019   
    P=N/A,  N=127, Completed, 
    Active, not recruiting --> Completed | Trial completion date: Jun 2018 --> Dec 2018 | Trial primary completion date: Jun 2018 --> Dec 2018 Active, not recruiting --> Completed | Trial completion date: Dec 2017 --> Dec 2018
  • ||||||||||  Trial completion, Enrollment change:  Investigative Headgear With CPAP Mask (clinicaltrials.gov) -  Apr 20, 2019   
    P=N/A,  N=23, Completed, 
    Active, not recruiting --> Completed | Trial completion date: Dec 2017 --> Dec 2018 Enrolling by invitation --> Completed | N=300 --> 23
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date:  SOMMEDREP: Sleep Respiratory Disorders Evaluation in Sickle Cell Disease Children (clinicaltrials.gov) -  Mar 14, 2019   
    P=N/A,  N=62, Completed, 
    Active, not recruiting --> Completed Active, not recruiting --> Completed | Trial completion date: Jan 2019 --> Aug 2018 | Trial primary completion date: Jan 2019 --> Aug 2018
  • ||||||||||  aspirin / Generic mfg.
    Trial completion date, Trial termination, Trial primary completion date:  ASpirin as a Treatment for ARDS (STAR): a Phase 2 Randomised Control Trial (clinicaltrials.gov) -  Mar 13, 2019   
    P2,  N=49, Terminated, 
    Active, not recruiting --> Completed | Trial completion date: Jan 2019 --> Aug 2018 | Trial primary completion date: Jan 2019 --> Aug 2018 Trial completion date: Jul 2017 --> Nov 2018 | Enrolling by invitation --> Terminated | Trial primary completion date: Jul 2017 --> Nov 2018; Slow recruitment
  • ||||||||||  midazolam hydrochloride / Generic mfg.
    Trial completion:  Pilot Study on Pairing Sedation Strategies and Weaning (clinicaltrials.gov) -  Mar 13, 2019   
    P=N/A,  N=90, Completed, 
    Trial completion date: Jul 2017 --> Nov 2018 | Enrolling by invitation --> Terminated | Trial primary completion date: Jul 2017 --> Nov 2018; Slow recruitment Recruiting --> Completed
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date, Surgery:  Randomized Control Trials of Surgery for Pediatric OSA (clinicaltrials.gov) -  Mar 6, 2019   
    P=N/A,  N=143, Completed, 
    Recruiting --> Completed Active, not recruiting --> Completed | Trial completion date: Oct 2026 --> Mar 2019 | Trial primary completion date: Dec 2018 --> Mar 2019
  • ||||||||||  dexamethasone injection / Generic mfg.
    Trial completion, Trial completion date, Trial primary completion date:  DEXA-ARDS: Efficacy Study of Dexamethasone to Treat the Acute Respiratory Distress Syndrome (clinicaltrials.gov) -  Feb 18, 2019   
    P4,  N=277, Completed, 
    Active, not recruiting --> Completed | Trial completion date: Dec 2018 --> Jun 2017 Recruiting --> Completed | Trial completion date: Oct 2018 --> Feb 2019 | Trial primary completion date: Oct 2018 --> Feb 2019
  • ||||||||||  Gastrocrom (cromolyn) / Viatris
    Trial termination:  Cromolyn Detection of Silent Aspiration (clinicaltrials.gov) -  Feb 16, 2019   
    P1,  N=16, Terminated, 
    Recruiting --> Completed | Trial completion date: Oct 2018 --> Feb 2019 | Trial primary completion date: Oct 2018 --> Feb 2019 Recruiting --> Terminated; Difficulty recruiting; Funding ended; interim analysis provided sufficient data for interpretation.
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date:  Fluid Shift on Obstructive and Central Sleep Apnea (clinicaltrials.gov) -  Feb 12, 2019   
    P=N/A,  N=36, Completed, 
    Recruiting --> Terminated; Difficulty recruiting; Funding ended; interim analysis provided sufficient data for interpretation. Recruiting --> Completed | Trial completion date: Jun 2018 --> Feb 2019 | Trial primary completion date: Jun 2018 --> Dec 2018
  • ||||||||||  Enrollment change, Trial withdrawal:  Autologous Umbilical Cord Blood Transfusion for Preterm Neonates (clinicaltrials.gov) -  Feb 12, 2019   
    P1,  N=0, Withdrawn, 
    Recruiting --> Completed | Trial completion date: Jun 2018 --> Feb 2019 | Trial primary completion date: Jun 2018 --> Dec 2018 N=60 --> 0 | Recruiting --> Withdrawn
  • ||||||||||  Trial completion:  Efficacy and Physiology of Nasal High Flow Therapy (clinicaltrials.gov) -  Feb 11, 2019   
    P=N/A,  N=46, Completed, 
    N=60 --> 0 | Recruiting --> Withdrawn Active, not recruiting --> Completed
  • ||||||||||  Trial completion, Trial primary completion date:  Evaluation of Cardiopulmonary Diseases by Ultrasound (clinicaltrials.gov) -  Feb 8, 2019   
    P=N/A,  N=600, Completed, 
    N=20 --> 0 Recruiting --> Completed | Trial primary completion date: Dec 2018 --> May 2018
  • ||||||||||  Phase classification, Enrollment change:  Mild Cognitive Impairment and Obstructive Sleep Apnea (clinicaltrials.gov) -  Jan 29, 2019   
    P=N/A,  N=54, Completed, 
    Recruiting --> Completed | Trial primary completion date: Dec 2018 --> May 2018 Phase classification: P3 --> P=N/A | N=86 --> 54
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date:  SAMSPAP: Sleep Apnea in Multiple Sclerosis Positive Airway Pressure Trial (clinicaltrials.gov) -  Jan 12, 2019   
    P=N/A,  N=49, Completed, 
    Recruiting --> Completed Recruiting --> Completed | Trial completion date: Mar 2019 --> Nov 2018 | Trial primary completion date: Sep 2018 --> Nov 2018
  • ||||||||||  valsartan / Generic mfg.
    Trial completion date, Trial termination:  Intermittent Hypoxia 2: Cardiovascular and Metabolism (clinicaltrials.gov) -  Dec 31, 2018   
    P4,  N=12, Terminated, 
    Recruiting --> Completed | Trial completion date: Mar 2019 --> Nov 2018 | Trial primary completion date: Sep 2018 --> Nov 2018 Trial completion date: Dec 2017 --> Mar 2017 | Active, not recruiting --> Terminated; budget constraints
  • ||||||||||  Trial completion date, Trial primary completion date:  SOMMEDREP: Sleep Respiratory Disorders Evaluation in Sickle Cell Disease Children (clinicaltrials.gov) -  Dec 22, 2018   
    P=N/A,  N=62, Active, not recruiting, 
    Trial completion date: Dec 2017 --> Mar 2017 | Active, not recruiting --> Terminated; budget constraints Trial completion date: Aug 2018 --> Jan 2019 | Trial primary completion date: Aug 2018 --> Jan 2019
  • ||||||||||  Enrollment change, Trial completion date, Trial termination, Trial primary completion date:  Clinical Trial of Nebulized Hypertonic Saline to Attenuate Post-Traumatic Acute Lung Injury (clinicaltrials.gov) -  Dec 20, 2018   
    P1,  N=13, Terminated, 
    Trial completion date: Aug 2018 --> Jan 2019 | Trial primary completion date: Aug 2018 --> Jan 2019 N=20 --> 13 | Trial completion date: May 2021 --> Nov 2018 | Recruiting --> Terminated | Trial primary completion date: May 2021 --> Nov 2018; low enrollment and loss of funding
  • ||||||||||  Enrollment change, Trial completion date, Trial termination, Trial primary completion date:  Lung and Systemic Inflammation in the Critically Ill Patient (clinicaltrials.gov) -  Dec 12, 2018   
    P=N/A,  N=8, Terminated, 
    N=20 --> 13 | Trial completion date: May 2021 --> Nov 2018 | Recruiting --> Terminated | Trial primary completion date: May 2021 --> Nov 2018; low enrollment and loss of funding N=18 --> 8 | Trial completion date: Nov 2017 --> Dec 2018 | Recruiting --> Terminated | Trial primary completion date: Nov 2016 --> Dec 2018; Slow enrollment and therefore not possible to reach the estimated enrollment
  • ||||||||||  Enrollment change, Trial completion date, Trial primary completion date:  Bi-Level Positive Airway Ventilation for Acute Chest Syndrome (clinicaltrials.gov) -  Dec 12, 2018   
    P=N/A,  N=3, Terminated, 
    N=18 --> 8 | Trial completion date: Nov 2017 --> Dec 2018 | Recruiting --> Terminated | Trial primary completion date: Nov 2016 --> Dec 2018; Slow enrollment and therefore not possible to reach the estimated enrollment N=60 --> 3 | Trial completion date: Jul 2014 --> Sep 2016 | Trial primary completion date: Jul 2014 --> Sep 2016
  • ||||||||||  Enrollment change:  Obesity Hypoventilation Syndrome Prevalence Study (clinicaltrials.gov) -  Dec 11, 2018   
    P=N/A,  N=44, Terminated, 
    N=60 --> 3 | Trial completion date: Jul 2014 --> Sep 2016 | Trial primary completion date: Jul 2014 --> Sep 2016 N=200 --> 44
  • ||||||||||  lansoprazole / Generic mfg.
    Enrollment change, Trial withdrawal:  Proton Pump Inhibitor Therapy for Mild to Moderate Obstructive Sleep Apnea (clinicaltrials.gov) -  Dec 10, 2018   
    P=N/A,  N=0, Withdrawn, 
    Active, not recruiting --> Completed | Trial completion date: Apr 2017 --> Jul 2017 N=50 --> 0 | Terminated --> Withdrawn
  • ||||||||||  Enrollment change:  Cycling of Sedative Infusions in Critically Ill Pediatric Patients (clinicaltrials.gov) -  Nov 23, 2018   
    P=N/A,  N=25, Terminated, 
    Active, not recruiting --> Terminated; Halted by the Management Committee after the publication of the ART Trial N=120 --> 25
  • ||||||||||  Enrollment change, Trial completion date, Trial withdrawal, Trial primary completion date:  Anti-MERS-CoV Convalescent Plasma Therapy (clinicaltrials.gov) -  Nov 21, 2018   
    P2,  N=0, Withdrawn, 
    N=200 --> 120 | Trial primary completion date: Jul 2013 --> Dec 2016 N=20 --> 0 | Trial completion date: Jun 2017 --> Nov 2016 | Active, not recruiting --> Withdrawn | Trial primary completion date: May 2017 --> May 2016
  • ||||||||||  Trial completion, Trial completion date, Trial primary completion date:  Impact of CPAP Therapy in Obstructive Sleep Apnea on Parameters of Nocturnal Pulse Wave Analysis (clinicaltrials.gov) -  Oct 30, 2018   
    P=N/A,  N=314, Completed, 
    N=20 --> 0 | Trial completion date: Jun 2017 --> Nov 2016 | Active, not recruiting --> Withdrawn | Trial primary completion date: May 2017 --> May 2016 Recruiting --> Completed | Trial completion date: Dec 2017 --> May 2017 | Trial primary completion date: Dec 2017 --> May 2017
  • ||||||||||  Trial completion, Phase classification, Trial completion date, Trial primary completion date:  ISAACC: Continuous Positive Airway Pressure (CPAP) in Patients With Acute Coronary Syndrome and Obstructive Sleep Apnea (OSA) (clinicaltrials.gov) -  Oct 18, 2018   
    P=N/A,  N=1864, Completed, 
    Recruiting --> Completed | Trial completion date: Dec 2017 --> May 2017 | Trial primary completion date: Dec 2017 --> May 2017 Recruiting --> Completed | Phase classification: P3 --> PN/A | Trial completion date: Apr 2018 --> Sep 2018 | Trial primary completion date: Sep 2017 --> Sep 2018
  • ||||||||||  Enrollment change:  STANDARDS: Stratification of the Acute Respiratory Distress Syndrome (clinicaltrials.gov) -  Oct 13, 2018   
    P=N/A,  N=300, Completed, 
    Recruiting --> Completed | Phase classification: P3 --> PN/A | Trial completion date: Apr 2018 --> Sep 2018 | Trial primary completion date: Sep 2017 --> Sep 2018 N=600 --> 300
  • ||||||||||  aspirin / Generic mfg.
    Enrollment change, Trial termination:  Aspirin Resistance and Sleep Apnea in Type-2 Diabetic Patients (clinicaltrials.gov) -  Oct 12, 2018   
    P=N/A,  N=53, Terminated, 
    N=600 --> 300 N=286 --> 53 | Recruiting --> Terminated; Recommendations changing
  • ||||||||||  Trial completion, Enrollment change:  FOCIS: Frequency of Oral Care Intervention Study (clinicaltrials.gov) -  Sep 21, 2018   
    P=N/A,  N=232, Completed, 
    N=50 --> 0 | Recruiting --> Withdrawn Recruiting --> Completed | N=345 --> 232