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6 Companies |
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10 Products |
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10 Products |
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13 Mechanisms of Action |
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0 Trials |
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280 News |
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- | Trial termination: BIODOP-T1: Early Placental Insufficiency Screening (clinicaltrials.gov) - May 16, 2023
P=N/A, N=226, Terminated, Sponsor: University Hospital, Tours
Completed --> Terminated; Shortness inclusions of patients
- | aspirin / Generic mfg.
Trial termination: PROVAS: Prevention of Preeclampsia With Aspirin in Recipients of Donated Oocytes. (clinicaltrials.gov) - Apr 26, 2019
P3, N=81, Terminated, Sponsor: Instituto de Investigacion Sanitaria La Fe
Completed --> Terminated; Shortness inclusions of patients Suspended --> Terminated; Halted prematurely due to low recruitment rate.
- | irbesartan / Generic mfg.
Trial completion date, Trial suspension, Trial primary completion date: Preeclampsia: A Marker for Future Cardiovascular Risk in Women (clinicaltrials.gov) - Jan 17, 2019
P=N/A, N=150, Suspended, Sponsor: Brigham and Women's Hospital
Suspended --> Terminated; Halted prematurely due to low recruitment rate. Trial completion date: Jun 2018 --> Jul 2019 | Recruiting --> Suspended | Trial primary completion date: Jun 2018 --> Jul 2017
- | Trial completion, Trial completion date: Free DNA and Nucleosome Concentrations in Pathological Pregnancies (clinicaltrials.gov) - Jan 11, 2019
P=N/A, N=137, Completed, Sponsor: Centre Hospitalier Universitaire de N?mes
Trial completion date: Jun 2018 --> Jul 2019 | Recruiting --> Suspended | Trial primary completion date: Jun 2018 --> Jul 2017 Active, not recruiting --> Completed | Trial completion date: Jun 2019 --> Dec 2018
- | NN1213 / Novo Nordisk
Trial completion: Accuracy Assessment of an Automatic Blood Pressure Measurement Device in Pregnant Women (clinicaltrials.gov) - Dec 20, 2018
P=N/A, N=43, Completed, Sponsor: William Marsh Rice University
Active, not recruiting --> Completed | Trial completion date: Jun 2019 --> Dec 2018 Active, not recruiting --> Completed
- | Trial completion date, Trial primary completion date: Free DNA and Nucleosome Concentrations in Pathological Pregnancies (clinicaltrials.gov) - Nov 26, 2018
P=N/A, N=180, Active, not recruiting, Sponsor: Centre Hospitalier Universitaire de N?mes
Active, not recruiting --> Completed Trial completion date: Dec 2018 --> Jun 2019 | Trial primary completion date: Jul 2018 --> Dec 2018
- | NN1213 / Novo Nordisk
Trial completion, Trial completion date: Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy (clinicaltrials.gov) - Nov 8, 2018
P4, N=894, Completed, Sponsor: Gynuity Health Projects
Trial completion date: Dec 2018 --> Jun 2019 | Trial primary completion date: Jul 2018 --> Dec 2018 Recruiting --> Completed | Trial completion date: Sep 2017 --> Dec 2017
- | hydralazine hydrochloride / Generic mfg., labetalol / Generic mfg.
Phase classification: Randomized Controlled Trial of Labetalol Versus Hydralazine for Severe Hypertension in Obstetric Patients. (clinicaltrials.gov) - Oct 26, 2018
P2, N=190, Completed, Sponsor: Dow University of Health Sciences
Recruiting --> Completed | Trial completion date: Sep 2017 --> Dec 2017 Phase classification: P2/3 --> P2
- | Trial completion, Phase classification: Effect of Micronutrients and Exercise During Pregnancy on Factors Related With Non-Transmissible Chronic Diseases (clinicaltrials.gov) - Oct 15, 2018
P=N/A, N=320, Completed, Sponsor: Universidad del Valle, Colombia
Phase classification: P2/3 --> P2 Not yet recruiting --> Completed | Phase classification: P2/3 --> PN/A
- | Trial completion, Enrollment change: Study of the Role of Tissular Maternofetal Alloimmunization in Placentation Pathologies (clinicaltrials.gov) - Aug 13, 2018
P=N/A, N=83, Completed, Sponsor: University Hospital, Limoges
Not yet recruiting --> Completed | Phase classification: P2/3 --> PN/A Recruiting --> Completed | N=150 --> 83
- | NN1213 / Novo Nordisk
Trial completion, Enrollment change: Prolongation of Pregnancy in Preeclampsia by Therapeutic Lipid Apheresis (clinicaltrials.gov) - Aug 9, 2018
P=N/A, N=6, Completed, Sponsor: Karl Winkler
Recruiting --> Completed | N=150 --> 83 Recruiting --> Completed | N=15 --> 6
- | aspirin / Generic mfg.
Trial termination: EPAPP: Early Prevention of Preeclampsia Study (clinicaltrials.gov) - Jul 3, 2018
P=N/A, N=104, Terminated, Sponsor: Washington University School of Medicine
Recruiting --> Completed | N=15 --> 6 Completed --> Terminated; Terminated after Aspirin was recommended by the USPTF to Prevent Preeclampsia.
- | Enrollment change, Trial termination: Endothelial Progenitor Cells in Umbilical Cord Blood in Preeclampsia and IUGR (clinicaltrials.gov) - Jun 15, 2018
P=N/A, N=11, Terminated, Sponsor: Medical University of South Carolina
Completed --> Terminated; Terminated after Aspirin was recommended by the USPTF to Prevent Preeclampsia. N=30 --> 11 | Not yet recruiting --> Terminated
- | Trial completion, Enrollment change: Alterations in the Plasma Proteome of Early-Onset Severe Preeclampsia (clinicaltrials.gov) - Jun 2, 2018
P=N/A, N=316, Completed, Sponsor: Medical University of South Carolina
N=30 --> 11 | Not yet recruiting --> Terminated Recruiting --> Completed | N=150 --> 316
- | benazepril / Generic mfg.
Trial completion, Trial completion date: RPPEC: Post-preeclampsia Renal Project: Study of Nephroprotection in Women Having Suffered Preeclampsia (clinicaltrials.gov) - May 1, 2018
P3, N=120, Completed, Sponsor: University Hospital, Geneva
Recruiting --> Completed | N=150 --> 316 Recruiting --> Completed | Trial completion date: Jun 2017 --> Mar 2018
- | aspirin / Generic mfg.
Enrollment change, Trial completion date, Trial suspension, Trial primary completion date: PROVAS: Prevention of Preeclampsia With Aspirin in Recipients of Donated Oocytes. (clinicaltrials.gov) - Mar 7, 2018
P3, N=81, Suspended, Sponsor: Instituto de Investigacion Sanitaria La Fe
Recruiting --> Completed | Trial completion date: Jun 2017 --> Mar 2018 N=372 --> 81 | Trial completion date: Dec 2017 --> May 2018 | Recruiting --> Suspended | Trial primary completion date: Aug 2017 --> May 2018
- | Enrollment change: Minimally-invasive Assessment of Cardiac Output in Severe Preeclampsia (clinicaltrials.gov) - Feb 6, 2018
P=N/A, N=0, Withdrawn, Sponsor: Samuel Lunenfeld Research Institute, Mount Sinai Hospital
N=372 --> 81 | Trial completion date: Dec 2017 --> May 2018 | Recruiting --> Suspended | Trial primary completion date: Aug 2017 --> May 2018 N=12 --> 0
- | Trial withdrawal, Compliance: A Comparison of Compliance Between Clonidine Patch and Methyldopa for the Treatment of Chronic Hypertension in Pregnancy (clinicaltrials.gov) - Jan 30, 2018
P=N/A, N=0, Withdrawn, Sponsor: Afshan B. Hameed, M.D.
N=12 --> 0 Terminated --> Withdrawn
- | thyroxine / Generic mfg.
Trial completion, Phase classification, Enrollment change, Trial primary completion date: Selenium Supplementation in Pregnancy (clinicaltrials.gov) - Jan 30, 2018
P=N/A, N=56, Completed, Sponsor: University of Roma La Sapienza
Terminated --> Withdrawn Recruiting --> Completed | Phase classification: P4 --> PN/A | N=150 --> 56 | Trial primary completion date: May 2015 --> Jun 2017
- | Enrollment closed: Free DNA and Nucleosome Concentrations in Pathological Pregnancies (clinicaltrials.gov) - Jan 26, 2018
P=N/A, N=180, Active, not recruiting, Sponsor: Centre Hospitalier Universitaire de N?mes
Recruiting --> Completed | Phase classification: P4 --> PN/A | N=150 --> 56 | Trial primary completion date: May 2015 --> Jun 2017 Recruiting --> Active, not recruiting
- | irbesartan / Generic mfg.
Trial primary completion date: Preeclampsia: A Marker for Future Cardiovascular Risk in Women (clinicaltrials.gov) - Jan 23, 2018
P=N/A, N=150, Recruiting, Sponsor: Brigham and Women's Hospital
Recruiting --> Active, not recruiting Trial primary completion date: Jun 2017 --> Jun 2018
- | Trial completion, Trial initiation date, Trial primary completion date: Restless Leg Syndrome and Severe Preeclampsia (clinicaltrials.gov) - Jan 4, 2018
P=N/A, N=310, Completed, Sponsor: Saint Thomas Hospital, Panama
Trial primary completion date: Jun 2017 --> Jun 2018 Recruiting --> Completed | Initiation date: Aug 2014 --> Aug 2017 | Trial primary completion date: Jul 2015 --> Nov 2017
- | Trial completion, Enrollment change: PLAC1 in Reproduction (clinicaltrials.gov) - Oct 26, 2017
P=N/A, N=500, Completed, Sponsor: University of South Florida
Recruiting --> Completed | Initiation date: Aug 2014 --> Aug 2017 | Trial primary completion date: Jul 2015 --> Nov 2017 Recruiting --> Completed | N=1000 --> 500
- | Trial completion: ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes (clinicaltrials.gov) - Oct 2, 2017
P=N/A, N=3442, Completed, Sponsor: Queen Mary University of London
Recruiting --> Completed | N=1000 --> 500 Active, not recruiting --> Completed
- Atenativ (human antithrombin III) / Octapharma
Trial withdrawal, Trial primary completion date: Atenativ Effect on Uterine Blood Flow and Preeclampsia (clinicaltrials.gov) - Sep 26, 2017
P4, N=0, Withdrawn, Sponsor: Vastra Gotaland Region
Active, not recruiting --> Completed Recruiting --> Withdrawn | Trial primary completion date: Dec 2017 --> May 2017
- | Enrollment change, Trial withdrawal: The Involvement of Eukaryotic Translation Initiation Factor 4E (eIF4E) in Human Placental Implantation and in the Pathological Pregnancies: Preeclampsia and IUGR (clinicaltrials.gov) - Sep 13, 2017
P=N/A, N=0, Withdrawn, Sponsor: Meir Medical Center
Recruiting --> Withdrawn | Trial primary completion date: Dec 2017 --> May 2017 N=120 --> 0 | Not yet recruiting --> Withdrawn
- | Biomarker, Trial completion, Trial primary completion date, Adverse events: Placental Growth and Adverse Pregnancy Outcomes (clinicaltrials.gov) - Jul 18, 2017
P=N/A, N=1043, Completed, Sponsor: University of Pennsylvania
N=120 --> 0 | Not yet recruiting --> Withdrawn Active, not recruiting --> Completed | Trial primary completion date: Oct 2016 --> Jun 2016
- || nifedipine immediate release / Generic mfg., labetalol / Generic mfg.
Trial primary completion date: Oral Antihypertensive Regimens for Management of Hypertension in Pregnancy (clinicaltrials.gov) - Jul 11, 2017
P4, N=894, Recruiting, Sponsor: Gynuity Health Projects
Active, not recruiting --> Completed | Trial primary completion date: Oct 2016 --> Jun 2016 Trial primary completion date: Jun 2017 --> Sep 2017
- | aspirin / Generic mfg.
Trial completion, Enrollment change: EPAPP: Early Prevention of Preeclampsia Study (clinicaltrials.gov) - Jun 7, 2017
P=N/A, N=104, Completed, Sponsor: Washington University School of Medicine
Trial primary completion date: Jun 2017 --> Sep 2017 Active, not recruiting --> Completed | N=684 --> 104
- | aspirin / Generic mfg.
Trial primary completion date: PROVAS: Prevention of Preeclampsia With Aspirin in Recipients of Donated Oocytes. (clinicaltrials.gov) - Jun 7, 2017
P3, N=372, Recruiting, Sponsor: Instituto de Investigacion Sanitaria La Fe
Active, not recruiting --> Completed | N=684 --> 104 Trial primary completion date: Dec 2017 --> Aug 2017
- | Enrollment change, Trial termination, Trial primary completion date: Health Improvement After Pregnancy (HIP) Program Randomized Control Trial (clinicaltrials.gov) - Apr 7, 2017
P=N/A, N=43, Terminated, Sponsor: Queen's University
Trial primary completion date: Dec 2017 --> Aug 2017 N=96 --> 43 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2017 --> Apr 2016; Poor retention and recruitment,changes need to be made to the program
- | Trial completion, Trial initiation date, Trial primary completion date: Placental Protein 13 Serum Endoglin and Uterine Doppler Indeces as Predictors of Pre-eclampsia (clinicaltrials.gov) - Mar 21, 2017
P=N/A, N=50, Completed, Sponsor: Cairo University
N=96 --> 43 | Active, not recruiting --> Terminated | Trial primary completion date: Jan 2017 --> Apr 2016; Poor retention and recruitment,changes need to be made to the program Recruiting --> Completed | Initiation date: Jan 2013 --> Jan 2015 | Trial primary completion date: May 2015 --> Dec 2016
- Phase classification: RAAPID-II: Removal of Anti-Angiogenic Proteins in Preeclampsia Before Delivery (clinicaltrials.gov) - Mar 15, 2017
P1b, N=11, Completed, Sponsor: Massachusetts General Hospital
Recruiting --> Completed | Initiation date: Jan 2013 --> Jan 2015 | Trial primary completion date: May 2015 --> Dec 2016 Phase classification: P1/2 --> P1b
- | aspirin / Generic mfg.
Trial completion: PERASTUN: Prevention of Pre-eclampsia and SGA by Low-Dose Aspirin in Nulliparous Women With Abnormal First-trimester Uterine Artery Dopplers (clinicaltrials.gov) - Feb 24, 2017
P4, N=1106, Completed, Sponsor: University Hospital, Tours
Phase classification: P1/2 --> P1b Active, not recruiting --> Completed
- ||||||| ATryn (antithrombin) / LFB SA, Knight Therap
Trial completion: PRESERVE-1: Pharmacokinetics, Safety and Efficacy Study of Recombinant Antithrombin Versus Placebo in Preterm Preeclampsia (clinicaltrials.gov) - Feb 9, 2017
P3, N=120, Completed, Sponsor: rEVO Biologics
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial completion, Enrollment change, Trial primary completion date: A Modernized Approach to Prenatal Care in Low Risk Women (clinicaltrials.gov) - Feb 6, 2017
P=N/A, N=4, Completed, Sponsor: Massachusetts General Hospital
Active, not recruiting --> Completed Not yet recruiting --> Completed | N=80 --> 4 | Trial primary completion date: Jul 2013 --> Apr 2014
- | Trial completion: MAG-PP: Magnesium Sulfate in Pregnancy and Postpartum (clinicaltrials.gov) - Feb 1, 2017
P2/3, N=280, Completed, Sponsor: Complejo Hospitalario Dr. Arnulfo Arias Madrid
Not yet recruiting --> Completed | N=80 --> 4 | Trial primary completion date: Jul 2013 --> Apr 2014 Recruiting --> Completed
- remifentanil / Generic mfg., dexmedetomidine / Generic mfg.
Intubation: Dexmedetomidine vs. Remifentanil for Pre-eclampsia During Caesarean Delivery (clinicaltrials.gov) - Jan 23, 2017
P2, N=50, Completed, Sponsor: Mansoura University
Recruiting --> Completed Recruiting --> Completed | N=36 --> 50 | Trial primary completion date: Feb 2016 --> Dec 2016
- Trial primary completion date: ESTEEM - Effect of Simple, Targeted Diet in Pregnant Women With Metabolic Risk Factors on Pregnancy Outcomes (clinicaltrials.gov) - Jan 17, 2017
P=N/A, N=3442, Active, not recruiting, Sponsor: Queen Mary University of London
Recruiting --> Completed | N=36 --> 50 | Trial primary completion date: Feb 2016 --> Dec 2016 Trial primary completion date: Aug 2016 --> Nov 2016
- labetalol / Generic mfg.
Enrollment change, Trial withdrawal, Trial primary completion date: LAMPET: Labetalol Versus Magnesium Sulfate (MgSO4) for the Prevention of Eclampsia Trial (clinicaltrials.gov) - Jan 13, 2017
P2/3, N=0, Withdrawn, Sponsor: Baylor College of Medicine
Trial primary completion date: Aug 2016 --> Nov 2016 N=8000 --> 0 | Suspended --> Withdrawn | Trial primary completion date: Jun 2020 --> Jan 2017
- irbesartan / Generic mfg.
Trial primary completion date: Preeclampsia: A Marker for Future Cardiovascular Risk in Women (clinicaltrials.gov) - Dec 28, 2016
P=N/A, N=150, Recruiting, Sponsor: Brigham and Women's Hospital
N=8000 --> 0 | Suspended --> Withdrawn | Trial primary completion date: Jun 2020 --> Jan 2017 Trial primary completion date: Sep 2016 --> Jun 2017
- | enoxaparin sodium / Generic mfg.
Trial completion: HOPPE: Low Weight Heparin prOphylaxis for Placental-Mediated Complications of PrEgnancy (clinicaltrials.gov) - Dec 21, 2016
P3, N=361, Completed, Sponsor: Hospital Universitari Vall d'Hebron Research Institute
Trial primary completion date: Sep 2016 --> Jun 2017 Active, not recruiting --> Completed
- aspirin / Generic mfg.
Trial completion: Effect of Low Dose Aspirin on Birthweight in Twins: The GAP Trial. (clinicaltrials.gov) - Dec 14, 2016
P2, N=50, Completed, Sponsor: Centre Hospitalier Universitaire de Qu
Active, not recruiting --> Completed Active, not recruiting --> Completed
- Trial completion: SNAP-HT: Self-management of Postnatal Anti-hypertensive Treatment: a Trial Development Pilot Study (clinicaltrials.gov) - Nov 30, 2016
P=N/A, N=101, Completed, Sponsor: University of Oxford
Active, not recruiting --> Completed Active, not recruiting --> Completed
- aspirin / Generic mfg.
Biomarker, Trial completion: ASPRE: Combined Multi-marker Screening and Treatment With Aspirin for Pre-eclampsia Prevention (clinicaltrials.gov) - Nov 9, 2016
P3, N=2, Completed, Sponsor: Rabin Medical Center
Active, not recruiting --> Completed Active, not recruiting --> Completed
- progesterone / Generic mfg.
Enrollment change, Trial withdrawal: Progesterone for First Trimester Vaginal Bleeding (clinicaltrials.gov) - Oct 26, 2016
P=N/A, N=0, Withdrawn, Sponsor: Soroka University Medical Center
Active, not recruiting --> Completed N=200 --> 0 | Not yet recruiting --> Withdrawn
- Enrollment change, Trial termination: CPAP in Preeclampsia (clinicaltrials.gov) - Oct 26, 2016
P=N/A, N=5, Terminated, Sponsor: University of Sydney
N=200 --> 0 | Not yet recruiting --> Withdrawn N=30 --> 5 | Recruiting --> Terminated; Poor recruitment
- Trial completion, Enrollment change: A Study of Cerebral-circulatory Response to Intravenous Antihypertensive Treatment in Women With Serious Preeclampsia (clinicaltrials.gov) - Oct 17, 2016
P4, N=8, Completed, Sponsor: Oslo University Hospital
N=30 --> 5 | Recruiting --> Terminated; Poor recruitment Recruiting --> Completed | N=50 --> 8
- Trial completion: Hemodynamic Measurements in Women With Serious Preeclampsia (clinicaltrials.gov) - Oct 17, 2016
P4, N=68, Completed, Sponsor: Oslo University Hospital
Recruiting --> Completed | N=50 --> 8 Recruiting --> Completed
- Trial primary completion date: Health Improvement After Pregnancy (HIP) Program Randomized Control Trial (clinicaltrials.gov) - Oct 11, 2016
P=N/A, N=96, Active, not recruiting, Sponsor: Queen's University
Recruiting --> Completed Trial primary completion date: Apr 2016 --> Jan 2017